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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for STAT5A

Z-value: 0.82

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
ENSG00000126561.18 STAT5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg38_v1_chr17_+_42288464_422885430.801.6e-06Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_120100688 4.51 ENST00000652264.1
notch receptor 2
chr2_+_151357583 3.61 ENST00000243347.5
TNF alpha induced protein 6
chr19_+_10271093 3.46 ENST00000423829.2
ENST00000588645.1
ENST00000264832.8
intercellular adhesion molecule 1
chr2_+_102355750 3.43 ENST00000233957.7
interleukin 18 receptor 1
chr2_+_102355881 3.37 ENST00000409599.5
interleukin 18 receptor 1
chr15_+_67166019 2.94 ENST00000537194.6
SMAD family member 3
chr10_-_48604952 2.65 ENST00000417912.6
Rho GTPase activating protein 22
chr1_-_153549238 2.54 ENST00000368713.8
S100 calcium binding protein A3
chr15_+_67138001 2.45 ENST00000439724.7
SMAD family member 3
chr4_-_76036060 2.40 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr14_+_22070548 2.40 ENST00000390450.3
T cell receptor alpha variable 22
chr3_+_122680802 2.39 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr11_-_102798148 2.25 ENST00000315274.7
matrix metallopeptidase 1
chr8_+_85245451 2.21 ENST00000321764.4
carbonic anhydrase 13
chr10_-_5977589 2.21 ENST00000620345.4
ENST00000397251.7
ENST00000397248.6
ENST00000622442.4
ENST00000620865.4
interleukin 15 receptor subunit alpha
chr13_-_42992165 2.20 ENST00000398762.7
ENST00000313640.11
ENST00000313624.12
epithelial stromal interaction 1
chr4_+_141636611 2.17 ENST00000514653.5
interleukin 15
chr10_-_5977535 2.14 ENST00000379977.8
interleukin 15 receptor subunit alpha
chr1_-_153549120 2.14 ENST00000368712.1
S100 calcium binding protein A3
chr1_-_173050931 2.13 ENST00000404377.5
TNF superfamily member 18
chr4_+_141636923 2.09 ENST00000529613.5
interleukin 15
chr21_+_41420515 2.08 ENST00000398600.6
ENST00000679626.1
MX dynamin like GTPase 1
chr21_-_44240840 2.07 ENST00000344330.8
ENST00000407780.7
ENST00000400379.7
ENST00000400377.3
inducible T cell costimulator ligand
chr1_-_40862354 1.94 ENST00000372638.4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr10_-_48605032 1.91 ENST00000249601.9
Rho GTPase activating protein 22
chr1_-_120051714 1.77 ENST00000579475.7
notch receptor 2
chr17_+_43006740 1.56 ENST00000438323.2
ENST00000415816.7
interferon induced protein 35
chr1_-_7940825 1.54 ENST00000377507.8
TNF receptor superfamily member 9
chr17_+_79025612 1.53 ENST00000392445.6
C1q and TNF related 1
chr6_+_4889992 1.47 ENST00000343762.5
chromodomain Y like
chr3_-_158732442 1.46 ENST00000479756.1
ENST00000237696.10
retinoic acid receptor responder 1
chr14_+_21990357 1.40 ENST00000390444.1
T cell receptor alpha variable 16
chr6_+_4706133 1.39 ENST00000328908.9
chromodomain Y like
chr17_+_42289213 1.37 ENST00000677301.1
signal transducer and activator of transcription 5A
chr3_-_64687613 1.34 ENST00000295903.8
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr19_+_56595279 1.30 ENST00000328070.10
ENST00000599599.7
ENST00000650950.1
zinc finger protein 71
ZIM2 antisense RNA 1
chr22_+_31248402 1.30 ENST00000333611.8
ENST00000340552.4
LIM domain kinase 2
chr1_-_89022827 1.30 ENST00000370481.9
ENST00000564665.1
guanylate binding protein 3
chr6_+_127577168 1.30 ENST00000329722.8
chromosome 6 open reading frame 58
chr22_+_31212207 1.29 ENST00000406516.5
ENST00000331728.9
LIM domain kinase 2
chr11_-_8810635 1.27 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr12_-_116881062 1.23 ENST00000550505.5
harakiri, BCL2 interacting protein
chr12_+_133080875 1.22 ENST00000412146.6
ENST00000544426.5
ENST00000355557.7
ENST00000319849.7
ENST00000440550.6
zinc finger protein 140
chr1_+_17580474 1.22 ENST00000375415.5
Rho guanine nucleotide exchange factor 10 like
chr6_+_144150492 1.19 ENST00000367568.5
syntaxin 11
chr14_-_91244669 1.15 ENST00000650645.1
G protein-coupled receptor 68
chr6_-_137219028 1.13 ENST00000647124.1
ENST00000642390.1
ENST00000645753.1
ENST00000646036.1
ENST00000646898.1
ENST00000644894.1
interferon gamma receptor 1
chr10_-_5977492 1.13 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr6_+_36676455 1.12 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr19_-_55160668 1.11 ENST00000588076.1
dynein axonemal assembly factor 3
chr8_-_47738153 1.09 ENST00000408965.4
CCAAT enhancer binding protein delta
chr16_-_11587450 1.06 ENST00000571688.5
lipopolysaccharide induced TNF factor
chr7_+_6104881 1.06 ENST00000306177.9
ENST00000465073.6
ubiquitin specific peptidase 42
chr18_+_58149314 1.05 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr17_+_42288464 1.04 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr2_+_108378176 1.03 ENST00000409309.3
sulfotransferase family 1C member 4
chr2_+_108377947 1.03 ENST00000272452.7
sulfotransferase family 1C member 4
chr15_+_63122561 1.00 ENST00000557972.1
lactamase beta
chr16_-_75464364 0.99 ENST00000569540.5
ENST00000566594.1
transmembrane protein 170A
novel TMEM170A-CFDP1 readthrough protein
chr19_+_10086787 0.99 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr11_+_94128834 0.97 ENST00000227638.8
ENST00000436171.2
pannexin 1
chr11_-_106022209 0.96 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr2_+_32628026 0.95 ENST00000448773.5
ENST00000317907.9
tetratricopeptide repeat domain 27
chr7_-_22356914 0.94 ENST00000344041.10
Rap guanine nucleotide exchange factor 5
chr9_+_100427254 0.94 ENST00000374885.5
Myb/SANT DNA binding domain containing 3
chr14_+_21070273 0.93 ENST00000555038.5
ENST00000298694.9
Rho guanine nucleotide exchange factor 40
chr10_+_113679159 0.92 ENST00000621345.4
ENST00000429617.5
ENST00000369331.8
caspase 7
chr16_+_50696999 0.92 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr6_+_36676489 0.92 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr6_-_30687200 0.88 ENST00000399199.7
protein phosphatase 1 regulatory subunit 18
chr18_-_47035621 0.87 ENST00000332567.6
elongin A2
chr11_+_69641146 0.87 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr8_-_118111806 0.86 ENST00000378204.7
exostosin glycosyltransferase 1
chr20_+_59676661 0.86 ENST00000355648.8
phosphatase and actin regulator 3
chr15_+_66453418 0.84 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chr1_+_206635573 0.84 ENST00000367108.7
dual specificity tyrosine phosphorylation regulated kinase 3
chr6_-_30686624 0.83 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr6_-_30684744 0.83 ENST00000615892.4
protein phosphatase 1 regulatory subunit 18
chr16_+_57619942 0.83 ENST00000568908.5
ENST00000568909.5
ENST00000566778.5
ENST00000561988.5
adhesion G protein-coupled receptor G1
chr15_+_63121818 0.82 ENST00000413507.3
lactamase beta
chr18_-_5396265 0.81 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr4_-_2756288 0.80 ENST00000510267.5
ENST00000315423.12
ENST00000503235.1
TNFAIP3 interacting protein 2
chr10_+_113679523 0.80 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr9_+_100427379 0.79 ENST00000622639.4
ENST00000374886.7
Myb/SANT DNA binding domain containing 3
chr2_+_102311502 0.79 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr3_-_187745460 0.76 ENST00000406870.7
BCL6 transcription repressor
chr6_+_36678699 0.76 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
cyclin dependent kinase inhibitor 1A
chr22_-_50085414 0.75 ENST00000311597.10
modulator of VRAC current 1
chr19_-_55738374 0.75 ENST00000590200.1
ENST00000332836.7
NLR family pyrin domain containing 9
chr5_+_150508110 0.75 ENST00000261797.7
N-deacetylase and N-sulfotransferase 1
chr10_+_102132994 0.74 ENST00000413464.6
ENST00000278070.7
PPARG related coactivator 1
chr14_-_91244508 0.74 ENST00000535815.5
ENST00000529102.1
G protein-coupled receptor 68
chr12_-_88580459 0.73 ENST00000552044.1
ENST00000644744.1
ENST00000357116.4
KIT ligand
chr17_+_79034185 0.73 ENST00000581774.5
C1q and TNF related 1
chr8_+_27771942 0.73 ENST00000523566.5
establishment of sister chromatid cohesion N-acetyltransferase 2
chr11_+_59144767 0.73 ENST00000527629.6
ENST00000361723.7
ENST00000531408.6
ENST00000420244.6
FAM111 trypsin like peptidase A
chr10_+_113679839 0.73 ENST00000369318.8
ENST00000369315.5
caspase 7
chr19_+_10086305 0.72 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr22_-_50085331 0.70 ENST00000395876.6
modulator of VRAC current 1
chr4_-_184474518 0.70 ENST00000393593.8
interferon regulatory factor 2
chr14_-_77423517 0.70 ENST00000555603.1
NADP dependent oxidoreductase domain containing 1
chr11_+_102347312 0.70 ENST00000621637.1
ENST00000613397.4
baculoviral IAP repeat containing 2
chr8_+_103298836 0.69 ENST00000523739.5
ENST00000358755.5
frizzled class receptor 6
chr17_-_35880350 0.69 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr5_-_115626161 0.69 ENST00000282382.8
TMED7-TICAM2 readthrough
chr5_+_121961955 0.68 ENST00000339397.5
serum response factor binding protein 1
chr18_-_77127935 0.67 ENST00000581878.5
myelin basic protein
chrX_+_150693360 0.67 ENST00000370390.7
ENST00000490316.6
ENST00000542156.5
ENST00000445323.7
myotubularin related protein 1
chr3_+_190615308 0.66 ENST00000412080.1
interleukin 1 receptor accessory protein
chr22_-_31107517 0.65 ENST00000400299.6
ENST00000611680.1
selenoprotein M
chr1_-_237004440 0.64 ENST00000464121.3
metallothionein 1H like 1
chr17_+_41105332 0.64 ENST00000391415.1
ENST00000617453.1
keratin associated protein 4-9
chr7_-_93226449 0.64 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr10_+_112283399 0.64 ENST00000643850.1
ENST00000646139.2
ENST00000645243.1
tectorin beta
chr19_+_42220283 0.63 ENST00000301215.8
ENST00000597945.1
zinc finger protein 526
chr21_+_33230375 0.61 ENST00000447980.1
interferon alpha and beta receptor subunit 2
chr15_-_38564635 0.61 ENST00000450598.6
ENST00000559830.5
ENST00000558164.5
ENST00000539159.5
ENST00000310803.10
RAS guanyl releasing protein 1
chr22_+_35648438 0.61 ENST00000409652.5
apolipoprotein L6
chr14_-_24429665 0.60 ENST00000267406.11
cerebellin 3 precursor
chr3_-_15333152 0.59 ENST00000426925.5
SH3 domain binding protein 5
chr10_+_88990531 0.59 ENST00000355740.7
Fas cell surface death receptor
chr19_+_43984167 0.59 ENST00000611002.4
ENST00000270014.7
ENST00000591532.5
ENST00000407951.6
ENST00000590615.5
ENST00000586454.1
zinc finger protein 155
chr10_+_88990736 0.58 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor
chr4_-_6070162 0.58 ENST00000636216.1
ENST00000637373.2
novel protein
janus kinase and microtubule interacting protein 1
chr15_+_63121852 0.58 ENST00000261893.9
lactamase beta
chr22_-_18024513 0.58 ENST00000441493.7
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr12_-_10998304 0.58 ENST00000538986.2
taste 2 receptor member 20
chr22_-_32255344 0.57 ENST00000266086.6
solute carrier family 5 member 4
chr6_-_57221402 0.56 ENST00000317483.4
RAB23, member RAS oncogene family
chr21_+_33324954 0.56 ENST00000270139.8
ENST00000442071.2
ENST00000652513.1
ENST00000652601.1
interferon alpha and beta receptor subunit 1
chr6_-_158819355 0.56 ENST00000367075.4
ezrin
chr6_+_108656346 0.56 ENST00000540898.1
forkhead box O3
chr4_+_168832005 0.55 ENST00000393726.7
ENST00000507735.6
palladin, cytoskeletal associated protein
chr10_+_88990621 0.55 ENST00000352159.8
Fas cell surface death receptor
chr22_+_24607638 0.55 ENST00000432867.5
gamma-glutamyltransferase 1
chr20_+_2814981 0.54 ENST00000603872.2
ENST00000380589.4
chromosome 20 open reading frame 141
chr1_-_146144804 0.54 ENST00000583866.9
ENST00000617010.2
NBPF member 10
chr10_-_84241538 0.53 ENST00000372105.4
leucine rich repeat, Ig-like and transmembrane domains 1
chr1_-_201469151 0.53 ENST00000367311.5
ENST00000367309.1
pleckstrin homology like domain family A member 3
chr22_+_20774092 0.53 ENST00000215727.10
serpin family D member 1
chr2_+_100974849 0.53 ENST00000450763.1
neuronal PAS domain protein 2
chr7_-_74254362 0.53 ENST00000352131.7
ENST00000055077.8
ENST00000621097.4
replication factor C subunit 2
chr17_+_34255274 0.52 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2
chr21_+_33230073 0.52 ENST00000342101.7
ENST00000413881.5
ENST00000443073.5
interferon alpha and beta receptor subunit 2
chr6_-_32816910 0.52 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr12_+_22046183 0.51 ENST00000229329.7
cytidine monophosphate N-acetylneuraminic acid synthetase
chr5_-_139482173 0.50 ENST00000652271.1
stimulator of interferon response cGAMP interactor 1
chr9_+_122159886 0.50 ENST00000373764.8
ENST00000536616.5
MORN repeat containing 5
chr14_+_67241278 0.50 ENST00000676464.1
membrane palmitoylated protein 5
chr19_-_57578872 0.49 ENST00000196489.4
zinc finger protein 416
chr3_+_77039836 0.49 ENST00000461745.5
roundabout guidance receptor 2
chr12_+_71664352 0.49 ENST00000547843.1
THAP domain containing 2
chrX_-_11427725 0.49 ENST00000380736.5
Rho GTPase activating protein 6
chr1_+_244352627 0.48 ENST00000366537.5
ENST00000308105.5
chromosome 1 open reading frame 100
chr11_-_133845495 0.48 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr22_-_30246739 0.47 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr20_-_44651683 0.47 ENST00000537820.1
ENST00000372874.9
adenosine deaminase
chr4_+_168497044 0.47 ENST00000505667.6
palladin, cytoskeletal associated protein
chr3_-_108222362 0.47 ENST00000492106.1
intraflagellar transport 57
chr17_+_34270213 0.45 ENST00000378569.2
ENST00000394627.5
ENST00000394630.3
C-C motif chemokine ligand 7
chr19_+_33374312 0.45 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr21_-_36079382 0.45 ENST00000399201.5
SET domain containing 4
chr2_+_130611440 0.44 ENST00000409602.2
POTE ankyrin domain family member J
chr4_+_168497066 0.44 ENST00000261509.10
palladin, cytoskeletal associated protein
chr11_-_62841809 0.44 ENST00000525239.5
ENST00000538098.2
WD repeat domain 74
chr11_-_105035113 0.44 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr20_-_1329131 0.44 ENST00000360779.4
syndecan binding protein 2
chr2_+_102187015 0.43 ENST00000441515.3
ENST00000264257.7
interleukin 1 receptor like 2
chr8_-_23854796 0.43 ENST00000290271.7
stanniocalcin 1
chr11_-_36510232 0.43 ENST00000348124.5
ENST00000526995.6
TNF receptor associated factor 6
chr19_-_6737234 0.42 ENST00000430424.8
ENST00000597298.5
G protein-coupled receptor 108
chr15_+_67254825 0.42 ENST00000629425.2
IQ motif containing H
chr11_+_117200188 0.42 ENST00000529792.5
transgelin
chr7_+_112423137 0.42 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr13_-_94596145 0.42 ENST00000261296.7
TDP-glucose 4,6-dehydratase
chr10_+_21534315 0.41 ENST00000377091.7
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr21_+_33229883 0.41 ENST00000382264.7
ENST00000342136.9
ENST00000404220.7
interferon alpha and beta receptor subunit 2
chr22_-_35622521 0.41 ENST00000419229.1
ENST00000406324.5
myoglobin
chr6_+_30163541 0.41 ENST00000376694.9
tripartite motif containing 15
chr12_+_55818033 0.40 ENST00000552672.5
ENST00000243045.10
ENST00000550836.1
ORMDL sphingolipid biosynthesis regulator 2
chr20_+_23350755 0.40 ENST00000254998.3
nuclear transport factor 2 like export factor 1
chr6_-_33580229 0.40 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BCL2 antagonist/killer 1
chr7_+_157337520 0.40 ENST00000412557.5
ENST00000453383.5
DnaJ heat shock protein family (Hsp40) member B6
chr10_-_27154365 0.39 ENST00000396296.7
ENST00000376016.8
ENST00000491542.6
ENST00000613434.4
YME1 like 1 ATPase
chr3_+_112333147 0.39 ENST00000473539.5
ENST00000315711.12
ENST00000383681.7
CD200 molecule
chr6_+_30163188 0.39 ENST00000619857.4
tripartite motif containing 15
chr2_-_144430934 0.39 ENST00000638087.1
ENST00000638007.1
zinc finger E-box binding homeobox 2
chr5_-_116536458 0.38 ENST00000510263.5
semaphorin 6A
chr11_-_48983826 0.38 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr11_-_117824734 0.38 ENST00000292079.7
FXYD domain containing ion transport regulator 2
chr22_-_36201800 0.38 ENST00000683024.1
apolipoprotein L4
chr17_+_7583828 0.38 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr14_+_67240713 0.38 ENST00000677382.1
membrane palmitoylated protein 5
chr11_+_73647549 0.38 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr4_+_145619371 0.37 ENST00000649156.2
ENST00000648388.1
metabolism of cobalamin associated A
chr5_-_60488055 0.37 ENST00000505507.6
ENST00000515835.2
ENST00000502484.6
phosphodiesterase 4D
chr12_+_10505890 0.37 ENST00000538173.1
eukaryotic translation initiation factor 2 subunit gamma B
chr1_+_171485520 0.37 ENST00000647382.2
ENST00000392078.7
ENST00000367742.7
ENST00000338920.8
proline rich coiled-coil 2C
chr22_+_18150162 0.37 ENST00000215794.8
ubiquitin specific peptidase 18
chr5_-_24644968 0.36 ENST00000264463.8
cadherin 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0045062 extrathymic T cell selection(GO:0045062)
0.9 7.6 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.9 5.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.7 3.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.5 2.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.5 1.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 6.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 2.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 1.6 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.3 2.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 2.8 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.3 2.4 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3 0.8 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.7 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 0.9 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 2.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 1.7 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 1.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.6 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 1.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 1.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.6 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.2 0.6 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.5 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501) negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 0.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.2 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 0.8 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.8 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.4 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.1 0.4 GO:0002339 B cell selection(GO:0002339)
0.1 0.8 GO:0008218 bioluminescence(GO:0008218)
0.1 2.5 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 1.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.3 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 1.7 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.7 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.3 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.4 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.6 GO:0032252 secretory granule localization(GO:0032252)
0.1 1.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.5 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.7 GO:0010269 response to selenium ion(GO:0010269)
0.1 1.2 GO:0070141 response to UV-A(GO:0070141)
0.1 2.9 GO:0030728 ovulation(GO:0030728)
0.1 0.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 1.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.7 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.3 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) response to cyclosporin A(GO:1905237)
0.1 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.9 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.3 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 2.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.7 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.1 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 3.3 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0046968 peptide antigen transport(GO:0046968)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.4 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.8 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 2.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.2 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.4 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.2 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.6 GO:0015816 glycine transport(GO:0015816)
0.0 1.6 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0071042 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0005999 xylulose biosynthetic process(GO:0005999)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 1.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 2.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.1 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.3 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.4 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.6 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.7 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0060631 regulation of meiosis I(GO:0060631)
0.0 0.1 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:1902563 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.0 0.3 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.4 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.2 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.2 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.8 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 1.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.0 GO:0035732 nitric oxide storage(GO:0035732)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:1990737 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.0 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.0 GO:0002876 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 1.4 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.3 GO:0002715 regulation of natural killer cell mediated immunity(GO:0002715)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.0 0.0 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.1 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.0 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0048023 regulation of melanin biosynthetic process(GO:0048021) positive regulation of melanin biosynthetic process(GO:0048023) regulation of secondary metabolite biosynthetic process(GO:1900376) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.6 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0060068 vagina development(GO:0060068)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.6 2.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 0.6 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 0.6 GO:1990423 RZZ complex(GO:1990423)
0.1 0.7 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.6 GO:0044393 microspike(GO:0044393)
0.1 1.1 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.6 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.5 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.1 0.9 GO:0070449 elongin complex(GO:0070449)
0.1 1.6 GO:0001741 XY body(GO:0001741)
0.1 0.2 GO:0071754 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.2 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.0 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.3 GO:0032010 phagolysosome(GO:0032010)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.0 3.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 2.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 2.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.2 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.0 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.9 5.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.7 6.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.6 2.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.5 2.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 2.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.3 0.3 GO:0032396 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.3 1.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 0.9 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3 1.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 0.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 1.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.4 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.3 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 2.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 3.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.5 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.1 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 1.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.2 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 1.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 1.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 2.5 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 4.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 2.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 3.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 2.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 5.0 GO:0005125 cytokine activity(GO:0005125)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.0 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 3.2 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 8.5 PID IL23 PATHWAY IL23-mediated signaling events
0.1 5.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 6.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 3.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 17.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 6.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.7 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 3.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 4.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions