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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for STAT6

Z-value: 0.55

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
STAT6
ENSG00000166888.12 STAT6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg38_v1_chr12_-_57110284_57110340,
hg38_v1_chr12_-_57129001_57129100		0.592.0e-03Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_40862354 1.91 ENST00000372638.4
CITED4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr11_-_128587551 1.62 ENST00000392668.8
ETS1
ETS proto-oncogene 1, transcription factor
chr5_+_119356011 1.38 ENST00000504771.3
ENST00000415806.2
TNFAIP8
TNF alpha induced protein 8
chr1_-_120100688 1.12 ENST00000652264.1
NOTCH2
notch receptor 2
chr6_-_32853618 0.93 ENST00000354258.5
TAP1
transporter 1, ATP binding cassette subfamily B member
chr6_-_32853813 0.92 ENST00000643049.2
TAP1
transporter 1, ATP binding cassette subfamily B member
chr4_-_115113822 0.78 ENST00000613194.4
NDST4
N-deacetylase and N-sulfotransferase 4
chr6_+_137867241 0.78 ENST00000612899.5
ENST00000420009.5
TNFAIP3
TNF alpha induced protein 3
chr6_+_32854179 0.69 ENST00000374859.3
PSMB9
proteasome 20S subunit beta 9
chr1_+_159437845 0.67 ENST00000642080.1
OR10J1
olfactory receptor family 10 subfamily J member 1
chr11_-_68213577 0.61 ENST00000402789.5
ENST00000402185.6
ENST00000458496.1
KMT5B
lysine methyltransferase 5B
chr14_-_24609660 0.60 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
GZMH
granzyme H
chr1_-_205422050 0.57 ENST00000367153.9
LEMD1
LEM domain containing 1
chr5_+_35856883 0.55 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr17_+_34255274 0.54 ENST00000580907.5
ENST00000225831.4
CCL2
C-C motif chemokine ligand 2
chr8_+_103298836 0.54 ENST00000523739.5
ENST00000358755.5
FZD6
frizzled class receptor 6
chr15_+_84981981 0.50 ENST00000339708.9
PDE8A
phosphodiesterase 8A
chr8_+_122781621 0.50 ENST00000314393.6
ZHX2
zinc fingers and homeoboxes 2
chr2_-_203535253 0.49 ENST00000457812.5
ENST00000319170.10
ENST00000630330.2
ENST00000308091.8
ENST00000453034.5
ENST00000420371.2
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr2_-_119366757 0.47 ENST00000414534.1
C2orf76
chromosome 2 open reading frame 76
chr12_-_6342066 0.47 ENST00000162749.7
ENST00000440083.6
TNFRSF1A
TNF receptor superfamily member 1A
chr15_+_66453418 0.47 ENST00000566326.1
MAP2K1
mitogen-activated protein kinase kinase 1
chr6_+_26440472 0.46 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
BTN3A3
butyrophilin subfamily 3 member A3
chr5_-_141958174 0.43 ENST00000231484.4
PCDH12
protocadherin 12
chr2_-_119366682 0.43 ENST00000409877.5
ENST00000409523.1
ENST00000409466.6
C2orf76
chromosome 2 open reading frame 76
chr15_+_84981834 0.42 ENST00000394553.6
PDE8A
phosphodiesterase 8A
chr3_+_41194741 0.41 ENST00000643541.1
ENST00000426215.5
ENST00000645210.1
ENST00000646381.1
ENST00000405570.6
ENST00000642248.1
ENST00000433400.6
CTNNB1
catenin beta 1
chr2_-_119366807 0.41 ENST00000334816.12
C2orf76
chromosome 2 open reading frame 76
chr12_-_51009264 0.40 ENST00000545993.7
SLC11A2
solute carrier family 11 member 2
chr5_-_147081428 0.39 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr4_+_95051671 0.37 ENST00000440890.7
BMPR1B
bone morphogenetic protein receptor type 1B
chr6_-_11232658 0.37 ENST00000379433.5
ENST00000379446.10
ENST00000620854.4
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr20_-_18497218 0.37 ENST00000337227.9
RBBP9
RB binding protein 9, serine hydrolase
chr15_-_100341899 0.35 ENST00000568565.2
ENST00000268070.9
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif 17
chr17_-_41350824 0.33 ENST00000007735.4
KRT33A
keratin 33A
chr14_+_22052503 0.33 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr3_+_141402322 0.31 ENST00000510338.5
ENST00000504673.5
ZBTB38
zinc finger and BTB domain containing 38
chr18_+_58196736 0.31 ENST00000675221.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr4_+_54100161 0.31 ENST00000326902.7
ENST00000503800.1
GSX2
GS homeobox 2
chr1_+_26432803 0.30 ENST00000430232.5
DHDDS
dehydrodolichyl diphosphate synthase subunit
chr11_+_73647549 0.28 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
PLEKHB1
pleckstrin homology domain containing B1
chr17_-_39778213 0.28 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3
chr10_+_100347225 0.28 ENST00000370355.3
SCD
stearoyl-CoA desaturase
chr4_+_72031902 0.27 ENST00000344413.6
ENST00000308744.12
NPFFR2
neuropeptide FF receptor 2
chrX_-_135764444 0.27 ENST00000597510.6
CT45A3
cancer/testis antigen family 45 member A3
chr16_-_74421756 0.26 ENST00000617101.4
CLEC18B
C-type lectin domain family 18 member B
chr6_-_24877262 0.26 ENST00000378023.8
ENST00000540914.5
RIPOR2
RHO family interacting cell polarization regulator 2
chr11_+_112961402 0.25 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
NCAM1
neural cell adhesion molecule 1
chr14_+_21918161 0.24 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr2_+_27537380 0.24 ENST00000447166.2
C2orf16
chromosome 2 open reading frame 16
chr16_-_67660694 0.24 ENST00000219251.13
ENST00000620338.4
ACD
ACD shelterin complex subunit and telomerase recruitment factor
chr2_+_68734861 0.23 ENST00000467265.5
ARHGAP25
Rho GTPase activating protein 25
chr13_-_51845169 0.23 ENST00000627246.3
ENST00000629372.3
TMEM272
transmembrane protein 272
chr11_-_60952134 0.23 ENST00000679573.1
ENST00000681882.1
ENST00000681951.1
ENST00000227880.8
SLC15A3
solute carrier family 15 member 3
chr17_+_7558296 0.23 ENST00000438470.5
ENST00000436057.5
TNFSF13
TNF superfamily member 13
chr5_-_147081462 0.23 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr12_+_12611839 0.22 ENST00000228865.3
CREBL2
cAMP responsive element binding protein like 2
chr16_-_74421392 0.22 ENST00000339953.9
ENST00000620745.1
ENST00000682950.1
CLEC18B
C-type lectin domain family 18 member B
chr4_-_46390039 0.22 ENST00000540012.5
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr2_+_119366924 0.21 ENST00000535757.5
ENST00000535617.5
ENST00000627093.2
ENST00000355857.8
ENST00000409094.5
ENST00000542275.5
ENST00000311521.8
DBI
diazepam binding inhibitor, acyl-CoA binding protein
chr17_+_36103819 0.21 ENST00000615863.2
ENST00000621626.1
CCL4
C-C motif chemokine ligand 4
chr11_-_60952559 0.21 ENST00000538739.2
SLC15A3
solute carrier family 15 member 3
chr19_-_42442938 0.21 ENST00000601181.6
CXCL17
C-X-C motif chemokine ligand 17
chr6_-_27912396 0.21 ENST00000303324.4
OR2B2
olfactory receptor family 2 subfamily B member 2
chr19_-_54100792 0.20 ENST00000391761.5
ENST00000356532.7
ENST00000616447.4
ENST00000359649.8
ENST00000358375.8
ENST00000391760.1
ENST00000351806.8
OSCAR
osteoclast associated Ig-like receptor
chr7_+_139133744 0.20 ENST00000430935.5
ENST00000495038.5
ENST00000474035.6
ENST00000478836.6
ENST00000464848.5
ENST00000343187.8
TTC26
tetratricopeptide repeat domain 26
chr2_-_174597728 0.20 ENST00000409891.5
ENST00000410117.5
WIPF1
WAS/WASL interacting protein family member 1
chr2_-_202870761 0.20 ENST00000420558.5
ENST00000418208.5
ICA1L
islet cell autoantigen 1 like
chr16_+_69950705 0.20 ENST00000615430.4
CLEC18A
C-type lectin domain family 18 member A
chr8_+_96493803 0.20 ENST00000518385.5
ENST00000302190.9
SDC2
syndecan 2
chr11_+_112961480 0.19 ENST00000621850.4
NCAM1
neural cell adhesion molecule 1
chr16_+_69950907 0.19 ENST00000393701.6
ENST00000568461.5
CLEC18A
C-type lectin domain family 18 member A
chr17_-_8867639 0.18 ENST00000619866.5
PIK3R6
phosphoinositide-3-kinase regulatory subunit 6
chr12_-_81758641 0.18 ENST00000552948.5
ENST00000548586.5
PPFIA2
PTPRF interacting protein alpha 2
chr2_+_68734773 0.18 ENST00000409202.8
ARHGAP25
Rho GTPase activating protein 25
chr11_+_65314853 0.18 ENST00000279249.3
CDC42EP2
CDC42 effector protein 2
chr8_+_39934955 0.18 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr6_-_27893175 0.17 ENST00000359611.4
H2AC17
H2A clustered histone 17
chr6_-_41286665 0.17 ENST00000589614.5
ENST00000244709.9
ENST00000334475.10
ENST00000591620.1
TREM1
triggering receptor expressed on myeloid cells 1
chr7_+_23598144 0.17 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr9_+_36572854 0.17 ENST00000543751.5
ENST00000536860.5
ENST00000541717.4
ENST00000536329.5
ENST00000536987.5
ENST00000298048.7
ENST00000495529.5
ENST00000545008.5
MELK
maternal embryonic leucine zipper kinase
chr1_-_153312919 0.17 ENST00000683862.1
PGLYRP3
peptidoglycan recognition protein 3
chr1_-_100178215 0.16 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
LRRC39
leucine rich repeat containing 39
chr4_-_120066777 0.16 ENST00000296509.11
MAD2L1
mitotic arrest deficient 2 like 1
chr7_-_75772172 0.16 ENST00000005180.9
CCL26
C-C motif chemokine ligand 26
chr17_+_38925168 0.16 ENST00000583195.2
LINC00672
long intergenic non-protein coding RNA 672
chr1_+_42153399 0.16 ENST00000372581.2
GUCA2B
guanylate cyclase activator 2B
chr11_-_60952067 0.16 ENST00000681275.1
SLC15A3
solute carrier family 15 member 3
chr4_-_10684749 0.15 ENST00000226951.11
CLNK
cytokine dependent hematopoietic cell linker
chr16_+_69951180 0.15 ENST00000288040.10
ENST00000449317.6
CLEC18A
C-type lectin domain family 18 member A
chrX_-_103064164 0.15 ENST00000372728.4
BEX1
brain expressed X-linked 1
chr9_-_132079856 0.15 ENST00000651555.1
ENST00000651950.1
ENST00000357028.6
ENST00000474263.1
ENST00000292035.10
MED27
mediator complex subunit 27
chr17_+_7558712 0.15 ENST00000338784.9
ENST00000625791.2
TNFSF13
TNF superfamily member 13
chr5_-_84384871 0.15 ENST00000296591.10
EDIL3
EGF like repeats and discoidin domains 3
chr11_+_112961247 0.14 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
NCAM1
neural cell adhesion molecule 1
chr1_+_213989691 0.14 ENST00000607425.1
PROX1
prospero homeobox 1
chr17_+_7558465 0.14 ENST00000349228.8
TNFSF13
TNF superfamily member 13
chr16_+_70173783 0.14 ENST00000541793.7
ENST00000314151.12
ENST00000565806.5
ENST00000569347.6
ENST00000536907.2
CLEC18C
C-type lectin domain family 18 member C
chr15_-_29822077 0.14 ENST00000677774.1
TJP1
tight junction protein 1
chr14_+_67720842 0.14 ENST00000267502.3
RDH12
retinol dehydrogenase 12
chr17_+_7558774 0.14 ENST00000396545.4
TNFSF13
TNF superfamily member 13
chr2_-_152175715 0.14 ENST00000263904.5
STAM2
signal transducing adaptor molecule 2
chr6_+_10555787 0.13 ENST00000316170.9
GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr12_-_81758665 0.13 ENST00000549325.5
ENST00000550584.6
PPFIA2
PTPRF interacting protein alpha 2
chr8_+_10095704 0.13 ENST00000382490.9
MSRA
methionine sulfoxide reductase A
chr8_+_10095551 0.13 ENST00000522907.5
ENST00000528246.5
MSRA
methionine sulfoxide reductase A
chr12_-_9999176 0.13 ENST00000298527.10
ENST00000348658.4
CLEC1B
C-type lectin domain family 1 member B
chr7_+_129375643 0.12 ENST00000490911.5
AHCYL2
adenosylhomocysteinase like 2
chr17_-_17836973 0.12 ENST00000261646.11
ENST00000355815.8
SREBF1
sterol regulatory element binding transcription factor 1
chr1_-_203229660 0.12 ENST00000255427.7
ENST00000367229.6
CHIT1
chitinase 1
chr1_+_149782671 0.11 ENST00000444948.5
ENST00000369168.5
FCGR1A
Fc fragment of IgG receptor Ia
chr5_-_74866958 0.11 ENST00000389156.9
FAM169A
family with sequence similarity 169 member A
chr13_+_48653921 0.11 ENST00000682523.1
CYSLTR2
cysteinyl leukotriene receptor 2
chr19_-_7702139 0.11 ENST00000346664.9
FCER2
Fc fragment of IgE receptor II
chr19_-_7702124 0.11 ENST00000597921.6
FCER2
Fc fragment of IgE receptor II
chr13_+_50015438 0.11 ENST00000312942.2
KCNRG
potassium channel regulator
chr13_+_50015254 0.11 ENST00000360473.8
KCNRG
potassium channel regulator
chr3_-_185938006 0.11 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
TRA2B
transformer 2 beta homolog
chr7_-_77199808 0.11 ENST00000248598.6
FGL2
fibrinogen like 2
chr15_-_29822028 0.10 ENST00000545208.6
TJP1
tight junction protein 1
chr13_+_73054969 0.10 ENST00000539231.5
KLF5
Kruppel like factor 5
chr2_-_201451446 0.10 ENST00000332624.8
ENST00000430254.1
TRAK2
trafficking kinesin protein 2
chr6_+_83512501 0.10 ENST00000369700.4
PRSS35
serine protease 35
chr10_-_59362584 0.10 ENST00000618427.4
ENST00000611933.4
FAM13C
family with sequence similarity 13 member C
chr10_-_59362460 0.10 ENST00000422313.6
ENST00000435852.6
ENST00000614220.4
ENST00000618804.5
ENST00000621119.4
FAM13C
family with sequence similarity 13 member C
chr1_-_241519701 0.10 ENST00000366560.4
ENST00000683521.1
FH
fumarate hydratase
chr17_+_7558258 0.09 ENST00000483039.5
ENST00000380535.8
ENST00000396542.5
TNFSF13
TNF superfamily member 13
chr9_-_133121228 0.09 ENST00000372050.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr1_-_153348825 0.09 ENST00000368739.3
ENST00000359650.10
PGLYRP4
peptidoglycan recognition protein 4
chr3_-_57199938 0.09 ENST00000473921.2
ENST00000295934.8
HESX1
HESX homeobox 1
chr16_-_67719300 0.09 ENST00000602279.2
ENST00000268797.12
ENST00000602855.2
ENST00000602377.1
GFOD2
glucose-fructose oxidoreductase domain containing 2
chr1_+_174447944 0.09 ENST00000367685.5
GPR52
G protein-coupled receptor 52
chr2_-_133568393 0.09 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCKAP5
NCK associated protein 5
chr2_-_26478032 0.09 ENST00000338581.10
ENST00000402415.8
OTOF
otoferlin
chr8_-_116874746 0.09 ENST00000297338.7
RAD21
RAD21 cohesin complex component
chr17_-_36534883 0.09 ENST00000620640.4
MYO19
myosin XIX
chr17_+_29941605 0.09 ENST00000394835.7
EFCAB5
EF-hand calcium binding domain 5
chr12_-_81759307 0.09 ENST00000547623.5
ENST00000549396.6
PPFIA2
PTPRF interacting protein alpha 2
chr17_+_36211055 0.08 ENST00000617405.5
ENST00000617416.4
ENST00000613173.4
ENST00000620732.4
ENST00000620098.4
ENST00000620576.4
ENST00000620055.4
ENST00000610565.4
ENST00000620250.1
CCL4L2
C-C motif chemokine ligand 4 like 2
chr4_+_183099244 0.08 ENST00000403733.8
WWC2
WW and C2 domain containing 2
chr1_-_160646958 0.08 ENST00000538290.2
SLAMF1
signaling lymphocytic activation molecule family member 1
chr17_-_36534841 0.08 ENST00000614623.5
ENST00000621344.4
MYO19
myosin XIX
chr6_+_30557287 0.08 ENST00000376560.8
PRR3
proline rich 3
chr2_-_26478113 0.08 ENST00000339598.8
OTOF
otoferlin
chrX_+_136169833 0.08 ENST00000628032.2
FHL1
four and a half LIM domains 1
chr7_+_55365317 0.08 ENST00000254770.3
LANCL2
LanC like 2
chr4_+_165378998 0.08 ENST00000402744.9
CPE
carboxypeptidase E
chr11_-_59212869 0.07 ENST00000361050.4
MPEG1
macrophage expressed 1
chr2_-_202871433 0.07 ENST00000457524.5
ENST00000421334.1
ENST00000617388.4
ICA1L
islet cell autoantigen 1 like
chr2_-_189179754 0.07 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chrX_-_139832235 0.07 ENST00000327569.7
ENST00000361648.6
ATP11C
ATPase phospholipid transporting 11C
chr5_+_150671588 0.07 ENST00000523553.1
MYOZ3
myozenin 3
chr4_+_6693870 0.07 ENST00000296370.4
S100P
S100 calcium binding protein P
chr22_-_29061831 0.07 ENST00000216071.5
C22orf31
chromosome 22 open reading frame 31
chr5_+_127649018 0.07 ENST00000379445.7
CTXN3
cortexin 3
chr17_+_36210924 0.07 ENST00000615418.4
CCL4L2
C-C motif chemokine ligand 4 like 2
chr15_+_78873723 0.07 ENST00000559690.5
ENST00000559158.5
MORF4L1
mortality factor 4 like 1
chr12_-_32755876 0.07 ENST00000324868.13
YARS2
tyrosyl-tRNA synthetase 2
chr18_+_13277351 0.06 ENST00000679091.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr15_+_91100194 0.06 ENST00000394232.6
SV2B
synaptic vesicle glycoprotein 2B
chr12_+_51888217 0.06 ENST00000340970.8
ANKRD33
ankyrin repeat domain 33
chr12_+_8992029 0.06 ENST00000543895.1
KLRG1
killer cell lectin like receptor G1
chr1_+_202462730 0.06 ENST00000290419.9
ENST00000491336.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr12_+_51888083 0.06 ENST00000301190.11
ANKRD33
ankyrin repeat domain 33
chr6_+_30557274 0.06 ENST00000376557.3
PRR3
proline rich 3
chr7_-_139716980 0.06 ENST00000342645.7
HIPK2
homeodomain interacting protein kinase 2
chr8_-_81447428 0.06 ENST00000256103.3
ENST00000519260.1
PMP2
peripheral myelin protein 2
chr8_-_30912998 0.06 ENST00000643185.2
TEX15
testis expressed 15, meiosis and synapsis associated
chr1_-_8026283 0.06 ENST00000474874.5
ENST00000469499.5
ENST00000377482.10
ERRFI1
ERBB receptor feedback inhibitor 1
chr1_-_201946469 0.06 ENST00000367288.5
LMOD1
leiomodin 1
chr1_+_34166883 0.05 ENST00000373374.7
C1orf94
chromosome 1 open reading frame 94
chrX_+_136169891 0.05 ENST00000449474.5
FHL1
four and a half LIM domains 1
chr17_+_7481332 0.05 ENST00000412468.3
SLC35G6
solute carrier family 35 member G6
chr5_+_139273752 0.05 ENST00000509990.5
ENST00000506147.5
ENST00000512107.5
MATR3
matrin 3
chr18_-_26865689 0.05 ENST00000675739.1
ENST00000383168.9
ENST00000672981.2
ENST00000578776.1
AQP4
aquaporin 4
chr17_-_3298360 0.05 ENST00000323404.2
OR3A1
olfactory receptor family 3 subfamily A member 1
chr4_-_46993520 0.05 ENST00000264318.4
GABRA4
gamma-aminobutyric acid type A receptor subunit alpha4
chrX_+_136169664 0.05 ENST00000456445.5
FHL1
four and a half LIM domains 1
chr2_-_60550900 0.05 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr11_+_70078291 0.05 ENST00000355303.9
ANO1
anoctamin 1
chr14_-_37172553 0.05 ENST00000331299.6
SLC25A21
solute carrier family 25 member 21
chr2_-_202870862 0.05 ENST00000454326.5
ENST00000432273.5
ENST00000450143.5
ENST00000411681.5
ICA1L
islet cell autoantigen 1 like
chr9_-_70869076 0.04 ENST00000677594.1
TRPM3
transient receptor potential cation channel subfamily M member 3
chr15_+_64094060 0.04 ENST00000560829.5
SNX1
sorting nexin 1
chr20_+_59676661 0.04 ENST00000355648.8
PHACTR3
phosphatase and actin regulator 3
chr4_-_46390273 0.04 ENST00000515082.5
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr1_-_160647287 0.04 ENST00000235739.6
SLAMF1
signaling lymphocytic activation molecule family member 1
chr16_+_30064462 0.03 ENST00000412304.6
ALDOA
aldolase, fructose-bisphosphate A
chr3_+_35641421 0.03 ENST00000449196.5
ARPP21
cAMP regulated phosphoprotein 21
chr6_+_31571957 0.03 ENST00000454783.5
LTA
lymphotoxin alpha
chr15_+_34345865 0.03 ENST00000333756.4
NUTM1
NUT midline carcinoma family member 1
chr3_-_98517096 0.03 ENST00000513873.1
CLDND1
claudin domain containing 1
chr11_+_8019193 0.03 ENST00000534099.5
TUB
TUB bipartite transcription factor
chr4_-_46390100 0.03 ENST00000381620.9
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr2_+_113127588 0.03 ENST00000409930.4
IL1RN
interleukin 1 receptor antagonist
chr2_-_151971750 0.02 ENST00000636598.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr18_-_26865732 0.02 ENST00000672188.1
AQP4
aquaporin 4
chr15_+_24954912 0.02 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
SNRPN
SNURF
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr10_-_95693893 0.02 ENST00000371209.5
ENST00000680144.1
ENST00000430368.6
ENST00000371217.10
TCTN3
tectonic family member 3
chr5_+_7396099 0.02 ENST00000338316.9
ADCY2
adenylate cyclase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 0.8 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 0.5 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 1.6 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.5 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.3 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.4 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.5 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 1.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.8 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.1 0.4 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.3 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:2000979 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.3 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.9 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.0 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0042825 TAP complex(GO:0042825)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.5 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440) MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.6 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.4 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.5 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.3 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism