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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TBX15_MGA

Z-value: 0.95

Motif logo

Transcription factors associated with TBX15_MGA

Gene Symbol Gene ID Gene Info
ENSG00000092607.15 TBX15
ENSG00000174197.17 MGA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX15hg38_v1_chr1_-_118989504_118989556,
hg38_v1_chr1_-_118988301_118988348
-0.096.5e-01Click!
MGAhg38_v1_chr15_+_41621134_41621258-0.077.5e-01Click!

Activity profile of TBX15_MGA motif

Sorted Z-values of TBX15_MGA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_159745186 4.89 ENST00000537657.5
superoxide dismutase 2
chr2_+_227813834 4.87 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr5_+_114362043 4.76 ENST00000673685.1
potassium calcium-activated channel subfamily N member 2
chr5_+_114362286 4.72 ENST00000610748.4
ENST00000264773.7
potassium calcium-activated channel subfamily N member 2
chr1_-_205321737 4.67 ENST00000367157.6
NUAK family kinase 2
chr17_+_79025612 4.29 ENST00000392445.6
C1q and TNF related 1
chr5_+_55024250 2.99 ENST00000231009.3
granzyme K
chr2_+_102355881 2.89 ENST00000409599.5
interleukin 18 receptor 1
chr2_+_102355750 2.79 ENST00000233957.7
interleukin 18 receptor 1
chr9_-_120914549 2.49 ENST00000546084.5
TNF receptor associated factor 1
chr6_+_36678699 2.23 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
cyclin dependent kinase inhibitor 1A
chr2_+_201129318 2.18 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr11_+_18455822 2.05 ENST00000615355.4
ENST00000396213.7
ENST00000280706.3
lactate dehydrogenase A like 6A
chr1_+_165827574 1.97 ENST00000367879.9
uridine-cytidine kinase 2
chr1_-_182672232 1.95 ENST00000508450.5
regulator of G protein signaling 8
chr21_+_36135071 1.86 ENST00000290354.6
carbonyl reductase 3
chr2_+_201129483 1.72 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr17_-_20467535 1.53 ENST00000324290.5
ENST00000423676.8
galectin 9B
chr2_+_202073282 1.44 ENST00000459709.5
KIAA2012
chr15_+_67067780 1.43 ENST00000679624.1
SMAD family member 3
chr13_-_29595670 1.43 ENST00000380752.10
solute carrier family 7 member 1
chr16_-_81077078 1.43 ENST00000565253.1
ENST00000378611.8
ENST00000299578.10
chromosome 16 open reading frame 46
chr2_+_202073249 1.42 ENST00000498697.3
KIAA2012
chr14_-_65102468 1.39 ENST00000555932.5
ENST00000284165.10
ENST00000358402.8
ENST00000246163.2
ENST00000358664.9
ENST00000556979.5
ENST00000555667.5
ENST00000557746.5
ENST00000556443.5
ENST00000618858.4
ENST00000557277.5
ENST00000556892.5
MYC associated factor X
chr5_-_124744513 1.37 ENST00000504926.5
zinc finger protein 608
chr11_-_86068929 1.36 ENST00000630913.2
phosphatidylinositol binding clathrin assembly protein
chr11_-_126062782 1.36 ENST00000531738.6
cell adhesion associated, oncogene regulated
chr17_-_41149823 1.33 ENST00000343246.6
keratin associated protein 4-5
chr10_-_97771954 1.30 ENST00000266066.4
secreted frizzled related protein 5
chr12_-_49707220 1.29 ENST00000550488.5
formin like 3
chr12_-_49707368 1.27 ENST00000352151.9
ENST00000335154.10
formin like 3
chr15_+_60004305 1.24 ENST00000396057.6
forkhead box B1
chr4_+_8580387 1.22 ENST00000382487.5
G protein-coupled receptor 78
chr1_+_28259473 1.17 ENST00000253063.4
sestrin 2
chr6_+_45422564 1.17 ENST00000625924.1
RUNX family transcription factor 2
chr20_+_46029206 1.16 ENST00000243964.7
solute carrier family 12 member 5
chr17_-_41060109 1.15 ENST00000391418.3
keratin associated protein 2-3
chr6_+_45422485 1.14 ENST00000359524.7
RUNX family transcription factor 2
chr11_+_61680373 1.11 ENST00000257215.10
diacylglycerol lipase alpha
chr19_+_38899680 1.09 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr1_+_26410809 1.07 ENST00000254231.4
ENST00000326279.11
lin-28 homolog A
chr20_+_46029165 1.07 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
solute carrier family 12 member 5
chr11_-_16356538 1.06 ENST00000683767.1
SRY-box transcription factor 6
chr14_+_94612383 1.05 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr10_-_90921079 1.04 ENST00000371697.4
ankyrin repeat domain 1
chrX_+_103607906 1.04 ENST00000243286.7
ENST00000372627.10
transcription elongation factor A like 3
chr1_-_26306576 1.04 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr4_-_170003738 1.03 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr7_-_80919017 1.01 ENST00000265361.8
semaphorin 3C
chr17_-_10549694 1.00 ENST00000622564.4
myosin heavy chain 2
chr3_-_108058361 0.99 ENST00000398258.7
CD47 molecule
chr11_-_615570 0.99 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr19_-_7926106 0.98 ENST00000318978.6
cortexin 1
chr9_+_99821876 0.96 ENST00000395097.7
nuclear receptor subfamily 4 group A member 3
chr4_-_145938473 0.96 ENST00000513320.5
zinc finger protein 827
chrX_+_70423031 0.95 ENST00000453994.6
ENST00000538649.5
ENST00000536730.5
glycerophosphodiester phosphodiesterase domain containing 2
chr12_-_48957365 0.94 ENST00000398092.4
ENST00000539611.1
novel protein
ADP ribosylation factor 3
chr19_-_1863497 0.94 ENST00000617223.1
ENST00000250916.6
Kruppel like factor 16
chrX_+_70423301 0.92 ENST00000374382.4
glycerophosphodiester phosphodiesterase domain containing 2
chr17_-_10549612 0.91 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr7_-_105679089 0.91 ENST00000477775.5
ataxin 7 like 1
chr17_+_27631148 0.90 ENST00000313648.10
ENST00000395473.7
ENST00000577392.5
ENST00000584661.5
galectin 9
chr17_-_7329266 0.89 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr4_+_139301478 0.88 ENST00000296543.10
ENST00000398947.1
N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr2_+_209771814 0.87 ENST00000673951.1
ENST00000673920.1
unc-80 homolog, NALCN channel complex subunit
chr17_-_10549652 0.87 ENST00000245503.10
myosin heavy chain 2
chr11_-_6481304 0.86 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr11_-_85719111 0.84 ENST00000529581.5
ENST00000533577.1
synaptotagmin like 2
chr6_+_82364234 0.84 ENST00000543496.3
trophoblast glycoprotein
chr11_-_85719160 0.83 ENST00000389958.7
ENST00000527794.5
synaptotagmin like 2
chr11_-_6481350 0.82 ENST00000423813.6
ENST00000614314.4
ADP ribosylation factor interacting protein 2
chr8_+_122781621 0.81 ENST00000314393.6
zinc fingers and homeoboxes 2
chr16_+_57186281 0.81 ENST00000564435.5
ENST00000562959.1
ENST00000568505.6
ENST00000394420.9
ENST00000537866.5
ring finger and SPRY domain containing 1
chr12_-_48957445 0.80 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ADP ribosylation factor 3
chr11_-_85719045 0.79 ENST00000533057.6
ENST00000533892.5
synaptotagmin like 2
chr1_-_225941212 0.79 ENST00000366820.10
left-right determination factor 2
chr10_+_110005804 0.76 ENST00000360162.7
adducin 3
chr5_-_173328407 0.76 ENST00000265087.9
stanniocalcin 2
chr14_+_54567612 0.76 ENST00000251091.9
ENST00000392067.7
ENST00000631086.2
sterile alpha motif domain containing 4A
chr12_-_26125023 0.75 ENST00000242728.5
basic helix-loop-helix family member e41
chr3_+_128051610 0.74 ENST00000464451.5
SEC61 translocon subunit alpha 1
chr14_+_54567100 0.74 ENST00000554335.6
sterile alpha motif domain containing 4A
chr1_-_225941383 0.74 ENST00000420304.6
left-right determination factor 2
chr11_-_64935882 0.73 ENST00000532246.1
ENST00000279168.7
glycoprotein hormone subunit alpha 2
chr2_+_153871909 0.73 ENST00000392825.8
ENST00000434213.1
polypeptide N-acetylgalactosaminyltransferase 13
chr6_+_30327259 0.73 ENST00000376659.9
ENST00000428555.1
tripartite motif containing 39
chr1_-_153070840 0.73 ENST00000368755.2
small proline rich protein 2B
chrX_+_16786421 0.72 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chrX_+_123184153 0.72 ENST00000616590.4
glutamate ionotropic receptor AMPA type subunit 3
chr3_-_197297523 0.72 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr2_+_209771972 0.71 ENST00000439458.5
ENST00000272845.10
unc-80 homolog, NALCN channel complex subunit
chr3_+_41194741 0.70 ENST00000643541.1
ENST00000426215.5
ENST00000645210.1
ENST00000646381.1
ENST00000405570.6
ENST00000642248.1
ENST00000433400.6
catenin beta 1
chr7_-_72966953 0.70 ENST00000395244.5
tripartite motif containing 74
chr2_-_2326378 0.69 ENST00000647618.1
myelin transcription factor 1 like
chr2_-_175005357 0.69 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr6_+_30326835 0.69 ENST00000440271.5
ENST00000376656.8
ENST00000396551.7
ENST00000428728.5
ENST00000396548.5
ENST00000428404.5
tripartite motif containing 39
chr7_-_44140372 0.68 ENST00000446581.5
myosin light chain 7
chr1_+_13061158 0.67 ENST00000681473.1
heterogeneous nuclear ribonucleoprotein C like 3
chr11_-_67508091 0.67 ENST00000531506.1
cyclin dependent kinase 2 associated protein 2
chr13_+_112894328 0.66 ENST00000375608.7
MCF.2 cell line derived transforming sequence like
chr1_-_13165631 0.66 ENST00000323770.8
heterogeneous nuclear ribonucleoprotein C like 4
chr9_-_133149334 0.65 ENST00000393160.7
ral guanine nucleotide dissociation stimulator
chr19_-_6416773 0.65 ENST00000595223.5
KH-type splicing regulatory protein
chr19_-_13906062 0.64 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr2_-_151971750 0.64 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chrX_+_71223216 0.63 ENST00000361726.7
gap junction protein beta 1
chr5_+_75511756 0.63 ENST00000241436.8
DNA polymerase kappa
chr9_+_99821846 0.63 ENST00000338488.8
ENST00000618101.4
nuclear receptor subfamily 4 group A member 3
chr15_-_58065734 0.63 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr15_-_58065703 0.63 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr11_-_67508152 0.62 ENST00000301488.8
cyclin dependent kinase 2 associated protein 2
chr19_-_45245386 0.62 ENST00000413988.3
exocyst complex component 3 like 2
chr17_+_44847905 0.61 ENST00000587021.1
HIG1 hypoxia inducible domain family member 1B
chr17_+_1716513 0.61 ENST00000455636.5
ENST00000468539.5
ENST00000437219.6
ENST00000309182.9
ENST00000446363.5
WD repeat domain 81
chr3_+_4493471 0.61 ENST00000544951.6
ENST00000650294.1
inositol 1,4,5-trisphosphate receptor type 1
chr4_-_145938422 0.60 ENST00000656985.1
ENST00000652097.1
ENST00000503462.3
ENST00000379448.9
ENST00000513840.2
zinc finger protein 827
chr12_-_48999363 0.59 ENST00000421952.3
dendrin
chr15_-_58065870 0.59 ENST00000537372.5
aldehyde dehydrogenase 1 family member A2
chr9_+_136952896 0.58 ENST00000371632.7
lipocalin 12
chr2_+_170715317 0.58 ENST00000375281.4
Sp5 transcription factor
chr3_-_190120881 0.58 ENST00000319332.10
prolyl 3-hydroxylase 2
chr3_+_9649433 0.57 ENST00000353332.9
ENST00000420925.5
ENST00000296003.9
ENST00000351233.9
myotubularin related protein 14
chr8_+_55102448 0.57 ENST00000622811.1
XK related 4
chr1_-_11847772 0.56 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr17_+_7307579 0.56 ENST00000572815.5
eukaryotic translation initiation factor 5A
chr9_+_34990250 0.55 ENST00000454002.6
ENST00000545841.5
DnaJ heat shock protein family (Hsp40) member B5
chr4_+_87650277 0.55 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr2_+_43637247 0.54 ENST00000282406.9
pleckstrin homology, MyTH4 and FERM domain containing H2
chr3_-_39154558 0.54 ENST00000514182.1
cysteine and serine rich nuclear protein 1
chr1_+_38991239 0.53 ENST00000432648.8
ENST00000446189.6
ENST00000372984.8
akirin 1
chr16_+_2537997 0.53 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr2_-_74465162 0.53 ENST00000649854.1
ENST00000650523.1
ENST00000649601.1
ENST00000448666.7
ENST00000409065.5
ENST00000414701.1
ENST00000452063.7
ENST00000649075.1
ENST00000648810.1
ENST00000462443.2
mannosyl-oligosaccharide glucosidase
chr5_+_141430499 0.52 ENST00000252085.4
protocadherin gamma subfamily A, 12
chr5_-_160852200 0.52 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr17_-_56833889 0.52 ENST00000397861.7
chromosome 17 open reading frame 67
chr17_+_44847874 0.52 ENST00000253410.3
HIG1 hypoxia inducible domain family member 1B
chr11_-_83682414 0.52 ENST00000404783.7
discs large MAGUK scaffold protein 2
chr12_-_113136224 0.52 ENST00000546530.5
ENST00000261729.9
RAS protein activator like 1
chr12_+_54549586 0.51 ENST00000243052.8
phosphodiesterase 1B
chr11_-_62984690 0.51 ENST00000421062.2
ENST00000458333.6
solute carrier family 22 member 6
chr3_+_4493340 0.51 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
inositol 1,4,5-trisphosphate receptor type 1
chr16_-_30010972 0.51 ENST00000565273.5
ENST00000567332.6
ENST00000350119.9
double C2 domain alpha
chr19_-_37906646 0.51 ENST00000303868.5
WD repeat domain 87
chr9_-_70414657 0.51 ENST00000377126.4
Kruppel like factor 9
chr12_-_113135710 0.50 ENST00000446861.7
RAS protein activator like 1
chr16_+_31033513 0.50 ENST00000313843.8
syntaxin 4
chr1_+_172659095 0.50 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr2_+_37196475 0.50 ENST00000397064.6
ENST00000402297.6
ENST00000406711.5
ENST00000392061.6
ENST00000397226.2
CEBPZ opposite strand
chr4_+_25234003 0.50 ENST00000264864.8
phosphatidylinositol 4-kinase type 2 beta
chr6_+_7541612 0.49 ENST00000418664.2
desmoplakin
chr11_-_86068743 0.49 ENST00000356360.9
phosphatidylinositol binding clathrin assembly protein
chr6_+_7541662 0.49 ENST00000379802.8
desmoplakin
chr10_-_6062290 0.49 ENST00000256876.10
ENST00000379954.5
interleukin 2 receptor subunit alpha
chr17_+_48107549 0.48 ENST00000580219.5
ENST00000452859.6
ENST00000393405.6
sorting nexin 11
chr11_-_69704013 0.48 ENST00000294312.4
fibroblast growth factor 19
chr12_-_116276759 0.48 ENST00000548743.2
mediator complex subunit 13L
chr17_+_48107743 0.48 ENST00000359238.7
ENST00000582104.5
ENST00000584335.5
sorting nexin 11
chr19_-_51024211 0.48 ENST00000593681.5
kallikrein related peptidase 11
chr17_-_79950828 0.48 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr1_-_112704921 0.48 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr11_+_73647549 0.48 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr14_+_50560137 0.48 ENST00000358385.12
atlastin GTPase 1
chr15_-_82647503 0.47 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr3_-_187745460 0.47 ENST00000406870.7
BCL6 transcription repressor
chr11_-_57237183 0.47 ENST00000606794.1
apelin receptor
chr1_+_151612001 0.47 ENST00000642376.1
ENST00000368843.8
ENST00000458013.7
sorting nexin 27
chr11_-_75351686 0.47 ENST00000360025.7
arrestin beta 1
chr8_+_737595 0.47 ENST00000637795.2
DLG associated protein 2
chr1_+_179591876 0.46 ENST00000294848.12
tudor domain containing 5
chr1_-_150808251 0.45 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr6_-_31652358 0.45 ENST00000456622.5
ENST00000435080.5
ENST00000375976.8
ENST00000441054.5
BAG cochaperone 6
chr6_-_62286161 0.45 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr1_-_226186673 0.44 ENST00000366812.6
acyl-CoA binding domain containing 3
chr12_-_213338 0.44 ENST00000424061.6
solute carrier family 6 member 12
chr5_-_116536458 0.44 ENST00000510263.5
semaphorin 6A
chr8_+_32647080 0.44 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr2_-_216860042 0.43 ENST00000236979.2
transition protein 1
chr2_-_135985568 0.43 ENST00000264161.9
aspartyl-tRNA synthetase 1
chr8_+_31640358 0.43 ENST00000523534.5
neuregulin 1
chr6_+_43771960 0.42 ENST00000230480.10
vascular endothelial growth factor A
chr12_-_62192762 0.41 ENST00000416284.8
TAFA chemokine like family member 2
chr1_+_179591819 0.41 ENST00000444136.6
tudor domain containing 5
chr19_+_3762665 0.40 ENST00000330133.5
mitochondrial ribosomal protein L54
chr4_-_185535498 0.40 ENST00000284767.12
ENST00000284771.7
ENST00000284770.10
ENST00000620787.5
ENST00000629667.2
PDZ and LIM domain 3
chr20_+_836052 0.40 ENST00000246100.3
family with sequence similarity 110 member A
chr16_+_30650728 0.40 ENST00000568754.5
proline rich 14
chr19_+_49119531 0.40 ENST00000334186.9
PTPRF interacting protein alpha 3
chr12_-_213656 0.40 ENST00000359674.8
solute carrier family 6 member 12
chr2_-_152099155 0.39 ENST00000637309.1
calcium voltage-gated channel auxiliary subunit beta 4
chrX_-_11427725 0.39 ENST00000380736.5
Rho GTPase activating protein 6
chr6_+_31946086 0.39 ENST00000425368.7
complement factor B
chr3_-_71493500 0.39 ENST00000648380.1
ENST00000650295.1
forkhead box P1
chr21_-_41508065 0.39 ENST00000398585.7
ENST00000424093.6
transmembrane serine protease 2
chr10_+_46375721 0.39 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
novel transcript
annexin A8 like 1
chr3_-_66500973 0.39 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr1_-_11848345 0.39 ENST00000376476.1
natriuretic peptide A
chrX_-_133415478 0.39 ENST00000370828.4
glypican 4
chr11_+_86800507 0.39 ENST00000533902.2
serine protease 23
chr15_+_84980440 0.38 ENST00000310298.8
ENST00000557957.5
phosphodiesterase 8A
chr19_-_37906588 0.38 ENST00000447313.7
WD repeat domain 87

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.0 4.9 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.7 5.7 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.7 9.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.6 4.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.5 2.0 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.5 2.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.4 1.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.4 1.6 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.4 1.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 1.9 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.4 3.9 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 1.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.3 0.9 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.3 0.9 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.3 0.9 GO:0007309 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.3 1.4 GO:1903826 arginine transmembrane transport(GO:1903826)
0.3 1.1 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.3 2.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 1.9 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 1.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 2.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 1.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 1.2 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.2 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 1.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 1.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 1.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 2.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 1.0 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 1.0 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 2.8 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.7 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 1.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.6 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.1 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.4 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.7 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 2.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.5 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.4 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.3 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.3 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.3 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.2 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662) cardiac cell fate determination(GO:0060913)
0.1 1.1 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 1.4 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 1.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.5 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 4.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.6 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.3 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.8 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.6 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 1.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.5 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.2 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.1 0.3 GO:0035803 egg coat formation(GO:0035803)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.1 0.2 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.7 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 1.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.5 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 1.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 1.0 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.9 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0044256 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.7 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.5 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.4 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.1 GO:1903823 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 2.5 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.3 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.2 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.4 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 1.6 GO:0048678 response to axon injury(GO:0048678)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:0071420 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.5 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.4 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.5 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.0 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.5 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 2.5 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.0 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.3 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0040031 snRNA modification(GO:0040031)
0.0 0.3 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.6 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.8 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.5 GO:0008038 neuron recognition(GO:0008038)
0.0 0.4 GO:0097435 fibril organization(GO:0097435)
0.0 0.0 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 2.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 1.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 3.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 1.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.1 1.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 0.7 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:1990742 microvesicle(GO:1990742)
0.1 0.9 GO:0071546 pi-body(GO:0071546)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.1 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 2.1 GO:0042629 mast cell granule(GO:0042629)
0.1 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 2.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 10.0 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.2 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 4.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.5 GO:0071203 WASH complex(GO:0071203)
0.0 0.9 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.3 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.3 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.6 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.6 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0042008 interleukin-18 receptor activity(GO:0042008)
1.6 4.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.9 9.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 1.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.5 4.9 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 2.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 1.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 2.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 1.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 1.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.7 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.2 1.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 2.0 GO:0004849 uridine kinase activity(GO:0004849)
0.2 2.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.9 GO:0048030 disaccharide binding(GO:0048030)
0.1 1.2 GO:0070728 leucine binding(GO:0070728)
0.1 0.6 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 2.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 3.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.4 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 2.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 2.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.4 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 2.9 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.4 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.5 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 1.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 1.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.6 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 1.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 3.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.9 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 4.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 4.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 4.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 4.4 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.5 ST GAQ PATHWAY G alpha q Pathway
0.1 2.9 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.7 PID ARF 3PATHWAY Arf1 pathway
0.1 2.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 4.4 PID FOXO PATHWAY FoxO family signaling
0.0 2.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 4.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 7.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 5.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.3 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 9.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 1.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 2.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.6 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C