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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TBX21_TBR1

Z-value: 0.60

Motif logo

Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
ENSG00000073861.3 TBX21
ENSG00000136535.15 TBR1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBR1hg38_v1_chr2_+_161416273_161416325-0.116.2e-01Click!
TBX21hg38_v1_chr17_+_47733228_47733242-0.048.6e-01Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_156332694 1.61 ENST00000424077.1
ENST00000426264.5
ENST00000421709.1
ENST00000339562.9
nuclear receptor subfamily 4 group A member 2
chr1_+_28259473 0.90 ENST00000253063.4
sestrin 2
chr11_-_27722021 0.89 ENST00000314915.6
brain derived neurotrophic factor
chr1_+_78620432 0.81 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
interferon induced protein 44 like
chr4_-_74038681 0.81 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr12_+_12785652 0.74 ENST00000356591.5
apolipoprotein L domain containing 1
chr1_+_78620722 0.74 ENST00000679848.1
interferon induced protein 44 like
chr19_+_13151975 0.73 ENST00000588173.1
immediate early response 2
chr7_+_27242796 0.70 ENST00000496902.7
even-skipped homeobox 1
chrX_+_140091415 0.69 ENST00000453380.2
novel protein (LOC389895)
chr14_+_75278820 0.66 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr22_+_40045451 0.66 ENST00000402203.5
trinucleotide repeat containing adaptor 6B
chr1_-_205321737 0.61 ENST00000367157.6
NUAK family kinase 2
chr15_+_60004305 0.58 ENST00000396057.6
forkhead box B1
chr6_+_168017873 0.57 ENST00000351261.4
ENST00000354419.6
kinesin family member 25
chr6_-_13487593 0.57 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr2_+_209771814 0.56 ENST00000673951.1
ENST00000673920.1
unc-80 homolog, NALCN channel complex subunit
chr6_-_30617232 0.53 ENST00000376511.7
protein phosphatase 1 regulatory subunit 10
chr2_+_209771972 0.53 ENST00000439458.5
ENST00000272845.10
unc-80 homolog, NALCN channel complex subunit
chr19_-_13102848 0.51 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr14_+_75280078 0.51 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr1_+_145927105 0.51 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr5_+_98769273 0.51 ENST00000308234.11
repulsive guidance molecule BMP co-receptor b
chr12_+_130953898 0.49 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr19_-_45245386 0.49 ENST00000413988.3
exocyst complex component 3 like 2
chr7_-_100168602 0.48 ENST00000423751.2
ENST00000360039.9
galactose-3-O-sulfotransferase 4
chr21_+_29130630 0.48 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr3_-_39154558 0.46 ENST00000514182.1
cysteine and serine rich nuclear protein 1
chr4_+_73869385 0.43 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr21_-_14546351 0.43 ENST00000619120.4
SAM domain, SH3 domain and nuclear localization signals 1
chr5_+_55024250 0.42 ENST00000231009.3
granzyme K
chr20_-_32657362 0.42 ENST00000360785.6
chromosome 20 open reading frame 203
chr4_+_8580387 0.41 ENST00000382487.5
G protein-coupled receptor 78
chr21_-_14546297 0.41 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr17_-_7329266 0.40 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr11_+_64306227 0.40 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr12_-_90955172 0.39 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr1_-_163202835 0.39 ENST00000527988.1
ENST00000531476.1
ENST00000530507.5
ENST00000313961.10
regulator of G protein signaling 5
chr15_+_40569290 0.39 ENST00000315616.12
ENST00000559271.1
ENST00000616318.1
RNA pseudouridine synthase domain containing 2
chr10_+_116545907 0.38 ENST00000369221.2
pancreatic lipase
chr4_+_123396785 0.37 ENST00000505319.5
ENST00000651917.1
ENST00000610581.4
ENST00000339241.1
sprouty RTK signaling antagonist 1
chr21_-_30497160 0.36 ENST00000334058.3
keratin associated protein 19-4
chr12_-_7872902 0.36 ENST00000431042.7
solute carrier family 2 member 14
chr3_-_61251376 0.36 ENST00000476844.5
ENST00000488467.5
ENST00000492590.6
ENST00000468189.5
fragile histidine triad diadenosine triphosphatase
chr5_-_35938572 0.35 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr10_+_92691813 0.34 ENST00000472590.6
hematopoietically expressed homeobox
chr1_+_182789765 0.34 ENST00000367555.5
ENST00000367553.6
N-acetylneuraminate pyruvate lyase
chr11_+_112961480 0.33 ENST00000621850.4
neural cell adhesion molecule 1
chr17_+_27471999 0.32 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
kinase suppressor of ras 1
chr17_+_42798779 0.32 ENST00000585355.5
cyclin N-terminal domain containing 1
chrX_-_129654946 0.32 ENST00000429967.3
apelin
chr5_+_134525649 0.32 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr3_-_129688691 0.31 ENST00000432054.6
transmembrane and coiled-coil domain family 1
chr5_+_150660841 0.30 ENST00000297130.4
myozenin 3
chr19_+_38289138 0.30 ENST00000590738.1
ENST00000587519.4
ENST00000591889.2
serine peptidase inhibitor, Kunitz type 2
novel protein
chr12_-_7872802 0.29 ENST00000535344.5
ENST00000543909.5
solute carrier family 2 member 14
chr15_+_89776326 0.28 ENST00000341735.5
mesoderm posterior bHLH transcription factor 2
chr12_-_7872843 0.28 ENST00000340749.9
ENST00000535295.5
ENST00000539234.5
solute carrier family 2 member 14
chr7_-_27095972 0.28 ENST00000355633.5
ENST00000643460.2
homeobox A1
chr11_-_111879425 0.27 ENST00000622211.4
novel protein
chr20_+_31605280 0.27 ENST00000376105.4
ENST00000376112.4
inhibitor of DNA binding 1, HLH protein
chr2_+_143129379 0.27 ENST00000295095.11
Rho GTPase activating protein 15
chr16_+_30201057 0.26 ENST00000569485.5
sulfotransferase family 1A member 3
chr1_+_147541491 0.26 ENST00000683836.1
ENST00000234739.8
BCL9 transcription coactivator
chr7_-_36724380 0.25 ENST00000617267.4
acyloxyacyl hydrolase
chr12_-_52367478 0.25 ENST00000257901.7
keratin 85
chr5_+_75511756 0.25 ENST00000241436.8
DNA polymerase kappa
chr11_-_28108109 0.25 ENST00000263181.7
kinesin family member 18A
chr16_+_69106219 0.25 ENST00000219322.7
hyaluronan synthase 3
chr5_+_35856883 0.24 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr22_-_17221841 0.24 ENST00000449907.7
ENST00000441548.1
ENST00000399839.5
adenosine deaminase 2
chr5_+_176238365 0.24 ENST00000341199.10
ENST00000430704.6
ENST00000443967.5
ENST00000429602.7
SUMO interacting motifs containing 1
chr16_-_20669855 0.23 ENST00000524149.5
acyl-CoA synthetase medium chain family member 1
chr5_+_150661243 0.23 ENST00000517768.6
myozenin 3
chr1_-_154859841 0.23 ENST00000361147.8
potassium calcium-activated channel subfamily N member 3
chr7_+_100429823 0.23 ENST00000310512.4
methylphosphate capping enzyme
chr10_-_22714531 0.22 ENST00000376573.9
phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
chr7_-_36724543 0.22 ENST00000612871.4
acyloxyacyl hydrolase
chr6_-_22302826 0.22 ENST00000651245.1
prolactin
chr16_+_11965193 0.22 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr15_+_47184076 0.22 ENST00000558014.5
semaphorin 6D
chr7_+_143316105 0.22 ENST00000343257.7
ENST00000650516.1
chloride voltage-gated channel 1
chr17_-_8163522 0.22 ENST00000404970.3
vesicle associated membrane protein 2
chr12_-_52703522 0.22 ENST00000341809.8
keratin 77
chr20_-_1557679 0.21 ENST00000381621.5
ENST00000381623.4
signal regulatory protein delta
chr19_-_43198079 0.21 ENST00000597374.5
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr12_+_109052564 0.21 ENST00000257548.10
ENST00000536723.5
ENST00000536393.5
ubiquitin specific peptidase 30
chr1_-_26306576 0.21 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr17_-_56833889 0.20 ENST00000397861.7
chromosome 17 open reading frame 67
chr11_+_73950985 0.20 ENST00000339764.6
DnaJ heat shock protein family (Hsp40) member B13
chr1_+_172659095 0.20 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr19_+_48019726 0.20 ENST00000593413.1
epididymal sperm binding protein 1
chr10_+_92691897 0.20 ENST00000492654.3
hematopoietically expressed homeobox
chr17_+_44847874 0.20 ENST00000253410.3
HIG1 hypoxia inducible domain family member 1B
chrX_-_19670983 0.20 ENST00000379716.5
SH3 domain containing kinase binding protein 1
chr4_+_185209577 0.20 ENST00000652585.1
sorting nexin 25
chr1_-_51990679 0.20 ENST00000371655.4
RAB3B, member RAS oncogene family
chr16_-_4345904 0.19 ENST00000571941.5
presequence translocase associated motor 16
chr7_-_36724457 0.19 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr15_+_63504511 0.19 ENST00000540797.5
ubiquitin specific peptidase 3
chr15_-_82647336 0.19 ENST00000617522.4
ENST00000684509.1
cytoplasmic polyadenylation element binding protein 1
chr17_+_36103819 0.19 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr2_+_232456146 0.19 ENST00000295463.4
alkaline phosphatase, intestinal
chr22_+_18110305 0.19 ENST00000680175.1
ENST00000426208.5
tubulin alpha 8
chrX_-_111410420 0.18 ENST00000371993.7
ENST00000680476.1
doublecortin
chr14_+_77116562 0.18 ENST00000557408.5
transmembrane protein 63C
chr17_+_44847905 0.18 ENST00000587021.1
HIG1 hypoxia inducible domain family member 1B
chr2_+_153871909 0.18 ENST00000392825.8
ENST00000434213.1
polypeptide N-acetylgalactosaminyltransferase 13
chr15_+_63504583 0.18 ENST00000380324.8
ENST00000561442.5
ENST00000560070.5
ubiquitin specific peptidase 3
chr16_-_30534819 0.17 ENST00000395094.3
zinc finger protein 747
chr2_-_218166951 0.17 ENST00000295683.3
C-X-C motif chemokine receptor 1
chr2_-_150487658 0.17 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr2_+_218382265 0.17 ENST00000233202.11
solute carrier family 11 member 1
chr22_-_40819324 0.17 ENST00000435456.7
ENST00000434185.1
ENST00000544408.5
solute carrier family 25 member 17
chr14_+_20999255 0.17 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr17_+_42798881 0.17 ENST00000588527.5
cyclin N-terminal domain containing 1
chr17_-_61928005 0.17 ENST00000444766.7
integrator complex subunit 2
chr17_+_42798857 0.17 ENST00000588408.6
cyclin N-terminal domain containing 1
chr17_-_61927968 0.17 ENST00000646954.1
ENST00000251334.7
ENST00000647009.1
integrator complex subunit 2
chr17_-_2711633 0.16 ENST00000435359.5
clustered mitochondria homolog
chr11_+_62665305 0.16 ENST00000532971.2
citrate synthase lysine methyltransferase
chr9_+_136658854 0.16 ENST00000371699.5
EGF like domain multiple 7
chr8_-_92095215 0.16 ENST00000360348.6
ENST00000520428.5
ENST00000518992.5
ENST00000520556.5
ENST00000518317.5
ENST00000521319.5
ENST00000521375.5
ENST00000518449.5
ENST00000613886.4
RUNX1 partner transcriptional co-repressor 1
chr8_-_98942557 0.16 ENST00000523601.5
serine/threonine kinase 3
chr7_-_44140372 0.16 ENST00000446581.5
myosin light chain 7
chr1_+_184386978 0.16 ENST00000235307.7
chromosome 1 open reading frame 21
chr12_+_57460127 0.16 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr6_-_32192845 0.16 ENST00000487761.5
G protein signaling modulator 3
chr6_+_167325071 0.16 ENST00000649884.1
ENST00000239587.10
tubulin tyrosine ligase like 2
chr11_+_112961402 0.16 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
neural cell adhesion molecule 1
chr14_+_23258485 0.16 ENST00000399905.5
ENST00000470456.1
ring finger protein 212B
chr12_+_57459782 0.16 ENST00000228682.7
GLI family zinc finger 1
chr14_-_75980993 0.15 ENST00000556285.1
transforming growth factor beta 3
chr2_+_241188509 0.15 ENST00000674324.1
ENST00000274979.12
anoctamin 7
chr5_-_138178599 0.15 ENST00000454473.5
ENST00000418329.5
ENST00000254900.10
ENST00000230901.9
ENST00000402931.5
ENST00000411594.6
ENST00000430331.1
bromodomain containing 8
chr7_+_27242700 0.15 ENST00000222761.7
even-skipped homeobox 1
chr1_-_11847772 0.15 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr6_+_30345131 0.15 ENST00000433076.6
ENST00000442966.7
ENST00000428040.6
ENST00000436442.2
ribonuclease P/MRP subunit p21
chr12_-_52291515 0.15 ENST00000615839.1
ENST00000327741.9
keratin 81
chr3_-_100993448 0.15 ENST00000495063.6
ENST00000486770.7
ENST00000530539.2
ABI family member 3 binding protein
chr1_+_150364136 0.15 ENST00000369068.5
regulation of nuclear pre-mRNA domain containing 2
chr11_+_28108248 0.15 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr17_-_41149823 0.15 ENST00000343246.6
keratin associated protein 4-5
chr20_-_45515612 0.15 ENST00000217428.7
serine peptidase inhibitor, Kunitz type 3
chr12_-_76486061 0.15 ENST00000548341.5
oxysterol binding protein like 8
chr19_+_12751789 0.14 ENST00000553030.6
bestrophin 2
chr10_+_7818497 0.14 ENST00000344293.6
TATA-box binding protein associated factor 3
chrX_+_110002635 0.14 ENST00000372072.7
transmembrane protein 164
chr15_-_43266857 0.14 ENST00000349114.8
ENST00000220420.10
transglutaminase 5
chr20_-_290364 0.14 ENST00000382369.9
chromosome 20 open reading frame 96
chr7_+_69967464 0.14 ENST00000664521.1
activator of transcription and developmental regulator AUTS2
chr19_+_45864318 0.14 ENST00000302177.3
forkhead box A3
chr1_+_200027605 0.14 ENST00000236914.7
nuclear receptor subfamily 5 group A member 2
chr9_-_136746006 0.14 ENST00000476567.1
lipocalin 6
chr8_-_42768781 0.14 ENST00000276410.7
cholinergic receptor nicotinic alpha 6 subunit
chr8_-_42768602 0.13 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr14_+_63761836 0.13 ENST00000674003.1
spectrin repeat containing nuclear envelope protein 2
chr5_-_71067601 0.13 ENST00000274400.9
ENST00000521602.2
ENST00000330280.11
ENST00000517900.5
general transcription factor IIH subunit 2
chr2_+_170715317 0.13 ENST00000375281.4
Sp5 transcription factor
chr15_-_72231583 0.13 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr11_-_236326 0.13 ENST00000525237.1
ENST00000382743.9
ENST00000532956.5
ENST00000525319.5
ENST00000524564.5
sirtuin 3
chr1_-_11848345 0.13 ENST00000376476.1
natriuretic peptide A
chr9_+_122519141 0.13 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr1_-_120176450 0.13 ENST00000578049.4
SEC22 homolog B, vesicle trafficking protein
chr5_-_75511596 0.13 ENST00000643158.1
ENST00000261415.12
ENST00000646713.1
ENST00000643773.1
ENST00000645866.1
ENST00000644072.2
ENST00000643780.2
ENST00000645483.1
ENST00000642556.1
ENST00000646511.1
ceramide transporter 1
chr6_+_36678699 0.13 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
cyclin dependent kinase inhibitor 1A
chr1_+_15736251 0.13 ENST00000294454.6
solute carrier family 25 member 34
chr1_+_26787926 0.13 ENST00000674202.1
ENST00000674222.1
phosphatidylinositol glycan anchor biosynthesis class V
chr19_+_12751672 0.13 ENST00000549706.5
bestrophin 2
chr17_+_6756035 0.12 ENST00000361842.8
ENST00000574907.5
XIAP associated factor 1
chr11_+_119149029 0.12 ENST00000619701.5
ATP binding cassette subfamily G member 4
chr6_-_52840843 0.12 ENST00000370989.6
glutathione S-transferase alpha 5
chr12_+_64780465 0.12 ENST00000542120.6
TBC1 domain family member 30
chr20_-_38033424 0.12 ENST00000373447.8
ENST00000373448.6
TELO2 interacting protein 1
chr6_+_43182165 0.12 ENST00000372647.6
ENST00000252050.9
cullin 9
chr11_+_6239068 0.12 ENST00000379936.3
cyclic nucleotide gated channel subunit alpha 4
chr16_-_75248190 0.12 ENST00000542031.6
BCAR1 scaffold protein, Cas family member
chr7_-_20786879 0.12 ENST00000418710.3
ENST00000617581.4
ENST00000361443.4
Sp8 transcription factor
chr6_-_84227596 0.12 ENST00000257766.8
centrosomal protein 162
chrX_-_101291325 0.12 ENST00000356784.2
TATA-box binding protein associated factor 7 like
chr19_-_344786 0.11 ENST00000264819.7
MIER family member 2
chr2_-_85668172 0.11 ENST00000428225.5
ENST00000519937.7
surfactant protein B
chr6_-_84227634 0.11 ENST00000617909.1
ENST00000403245.8
centrosomal protein 162
chr7_+_111091006 0.11 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr7_-_138701352 0.11 ENST00000421622.5
ENST00000674285.1
SVOP like
chr22_+_30607145 0.11 ENST00000405742.7
transcobalamin 2
chr16_+_88706458 0.11 ENST00000312060.9
ENST00000453996.7
ENST00000567949.5
ENST00000564921.1
cytosolic thiouridylase subunit 2
chr17_-_10026265 0.11 ENST00000437099.6
ENST00000396115.6
growth arrest specific 7
chr2_+_60881553 0.11 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chrX_+_152759218 0.11 ENST00000599845.3
ENST00000638835.1
CSAG family member 3
chr8_+_22570944 0.11 ENST00000517962.1
sorbin and SH3 domain containing 3
chr20_-_290717 0.11 ENST00000360321.7
ENST00000400269.4
chromosome 20 open reading frame 96
chr19_-_50025936 0.11 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr19_+_37371152 0.11 ENST00000483919.5
ENST00000588911.5
ENST00000587349.1
zinc finger protein 527
chr2_+_1414382 0.11 ENST00000423320.5
ENST00000346956.7
ENST00000382198.5
thyroid peroxidase
chr17_-_39401593 0.11 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
F-box and leucine rich repeat protein 20
chr15_-_89751292 0.11 ENST00000300057.4
mesoderm posterior bHLH transcription factor 1
chr2_+_60881515 0.11 ENST00000295025.12
REL proto-oncogene, NF-kB subunit
chr16_+_6019071 0.11 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr10_+_112375196 0.11 ENST00000393081.6
acyl-CoA synthetase long chain family member 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 0.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 0.9 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.3 0.9 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 0.6 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 0.5 GO:0061011 hepatic duct development(GO:0061011)
0.1 0.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 1.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.6 GO:0007412 axon target recognition(GO:0007412)
0.1 0.2 GO:0040031 snRNA modification(GO:0040031)
0.1 0.3 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.3 GO:0060032 notochord regression(GO:0060032)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.1 0.2 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac cell fate determination(GO:0060913) negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.5 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.7 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0010931 macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 1.0 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.1 GO:1902617 response to fluoride(GO:1902617)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515) midbrain morphogenesis(GO:1904693)
0.0 0.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.0 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.7 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.7 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.0 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.0 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0035976 AP1 complex(GO:0035976)
0.1 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.5 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.9 GO:0070728 leucine binding(GO:0070728)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.0 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules