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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TBX4

Z-value: 0.48

Motif logo

Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
ENSG00000121075.11 TBX4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg38_v1_chr17_+_61452378_61452437-0.331.1e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_61203496 2.15 ENST00000663597.1
nuclear factor I A
chr4_-_185810894 1.79 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr11_-_33892010 1.04 ENST00000257818.3
LIM domain only 2
chr1_+_145927105 0.95 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr4_+_185209577 0.90 ENST00000652585.1
sorting nexin 25
chr4_-_101347327 0.84 ENST00000394853.8
protein phosphatase 3 catalytic subunit alpha
chr4_-_101347492 0.81 ENST00000394854.8
protein phosphatase 3 catalytic subunit alpha
chr11_-_33869816 0.80 ENST00000395833.7
LIM domain only 2
chr3_+_134795248 0.77 ENST00000398015.8
EPH receptor B1
chr4_-_101347471 0.76 ENST00000323055.10
ENST00000512215.5
protein phosphatase 3 catalytic subunit alpha
chr6_-_13487593 0.74 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr9_-_72953047 0.73 ENST00000297785.8
ENST00000376939.5
aldehyde dehydrogenase 1 family member A1
chr2_+_60881553 0.64 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chr8_+_94895763 0.64 ENST00000523378.5
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr2_+_60881515 0.62 ENST00000295025.12
REL proto-oncogene, NF-kB subunit
chr5_+_69492767 0.61 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
occludin
chr11_-_27722021 0.59 ENST00000314915.6
brain derived neurotrophic factor
chr2_-_156332694 0.52 ENST00000424077.1
ENST00000426264.5
ENST00000421709.1
ENST00000339562.9
nuclear receptor subfamily 4 group A member 2
chr10_+_93073873 0.49 ENST00000224356.5
cytochrome P450 family 26 subfamily A member 1
chr17_+_37489882 0.48 ENST00000617516.5
dual specificity phosphatase 14
chrX_-_134796256 0.47 ENST00000486347.5
PABIR family member 2
chr1_+_26787926 0.44 ENST00000674202.1
ENST00000674222.1
phosphatidylinositol glycan anchor biosynthesis class V
chr12_-_7695752 0.42 ENST00000329913.4
growth differentiation factor 3
chr7_+_107580215 0.41 ENST00000465919.5
ENST00000005259.9
ENST00000445771.6
ENST00000479917.5
ENST00000421217.5
ENST00000457837.5
B cell receptor associated protein 29
chr19_+_35031263 0.40 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr17_-_39401593 0.40 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
F-box and leucine rich repeat protein 20
chr4_-_113761441 0.38 ENST00000394524.7
calcium/calmodulin dependent protein kinase II delta
chr4_-_113761724 0.38 ENST00000511664.6
calcium/calmodulin dependent protein kinase II delta
chr7_-_120857124 0.37 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr3_+_134795277 0.37 ENST00000647596.1
EPH receptor B1
chr10_+_44911316 0.35 ENST00000544540.5
ENST00000389583.5
transmembrane protein 72
chr2_+_62705866 0.35 ENST00000263991.9
EH domain binding protein 1
chr19_-_46023046 0.32 ENST00000008938.5
peptidoglycan recognition protein 1
chr4_-_113761927 0.32 ENST00000296402.9
calcium/calmodulin dependent protein kinase II delta
chr1_+_26787667 0.31 ENST00000674335.1
phosphatidylinositol glycan anchor biosynthesis class V
chr2_+_62705644 0.31 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EH domain binding protein 1
chr13_+_114281577 0.29 ENST00000375299.8
ENST00000492270.1
ENST00000351487.5
UPF3A regulator of nonsense mediated mRNA decay
chr1_+_26788166 0.29 ENST00000374145.6
ENST00000431541.6
ENST00000674273.1
phosphatidylinositol glycan anchor biosynthesis class V
chr11_-_18322122 0.28 ENST00000349215.8
ENST00000396253.7
ENST00000438420.6
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
chr12_+_103930600 0.28 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chrX_-_19670983 0.27 ENST00000379716.5
SH3 domain containing kinase binding protein 1
chr2_-_197675578 0.27 ENST00000295049.9
raftlin family member 2
chr21_+_29130630 0.26 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr17_-_45425620 0.26 ENST00000376922.6
Rho GTPase activating protein 27
chr17_-_49677976 0.25 ENST00000665825.1
ENST00000508805.5
ENST00000515508.6
ENST00000451526.6
ENST00000507970.5
speckle type BTB/POZ protein
chr8_+_102551583 0.25 ENST00000285402.4
outer dense fiber of sperm tails 1
chr22_+_40045451 0.25 ENST00000402203.5
trinucleotide repeat containing adaptor 6B
chr7_+_107580454 0.25 ENST00000379117.6
ENST00000473124.1
B cell receptor associated protein 29
chr11_-_111879425 0.24 ENST00000622211.4
novel protein
chr8_-_98942557 0.24 ENST00000523601.5
serine/threonine kinase 3
chr11_-_114400417 0.24 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr7_+_27242700 0.24 ENST00000222761.7
even-skipped homeobox 1
chrX_+_123961696 0.23 ENST00000371145.8
ENST00000371157.7
ENST00000371144.7
stromal antigen 2
chr16_+_69105636 0.23 ENST00000569188.6
hyaluronan synthase 3
chr15_+_41621134 0.23 ENST00000566718.6
MAX dimerization protein MGA
chr2_+_102473219 0.23 ENST00000295269.5
solute carrier family 9 member A4
chr12_-_89630552 0.22 ENST00000393164.6
ATPase plasma membrane Ca2+ transporting 1
chrX_+_124346525 0.22 ENST00000360027.4
SH2 domain containing 1A
chr11_+_111878926 0.22 ENST00000528125.5
chromosome 11 open reading frame 1
chr4_-_139301204 0.22 ENST00000505036.5
ENST00000539002.5
ENST00000544855.5
NADH:ubiquinone oxidoreductase subunit C1
chr5_-_75511596 0.22 ENST00000643158.1
ENST00000261415.12
ENST00000646713.1
ENST00000643773.1
ENST00000645866.1
ENST00000644072.2
ENST00000643780.2
ENST00000645483.1
ENST00000642556.1
ENST00000646511.1
ceramide transporter 1
chr18_-_55401751 0.21 ENST00000537856.7
transcription factor 4
chr10_+_7818497 0.20 ENST00000344293.6
TATA-box binding protein associated factor 3
chr4_-_145938775 0.20 ENST00000508784.6
zinc finger protein 827
chr3_+_63819368 0.20 ENST00000616659.1
chromosome 3 open reading frame 49
chr1_+_154405326 0.20 ENST00000368485.8
interleukin 6 receptor
chr8_+_55102448 0.20 ENST00000622811.1
XK related 4
chr3_+_63819341 0.20 ENST00000647022.1
chromosome 3 open reading frame 49
chr20_+_11917859 0.20 ENST00000618296.4
ENST00000378226.7
BTB domain containing 3
chr2_-_199457931 0.20 ENST00000417098.6
SATB homeobox 2
chr14_+_22875136 0.19 ENST00000551466.1
LDL receptor related protein 10
chr3_-_49422429 0.19 ENST00000637682.1
ENST00000427987.6
ENST00000636199.1
ENST00000638063.1
ENST00000636865.1
ENST00000458307.6
ENST00000273588.9
ENST00000635808.1
ENST00000636522.1
ENST00000636597.1
ENST00000538581.6
ENST00000395338.7
ENST00000462048.2
aminomethyltransferase
chr17_-_41047267 0.19 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr16_+_67562453 0.19 ENST00000646076.1
CCCTC-binding factor
chr5_+_134525649 0.19 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chrX_+_124346571 0.18 ENST00000477673.2
SH2 domain containing 1A
chr12_-_52703522 0.18 ENST00000341809.8
keratin 77
chr16_+_85611401 0.18 ENST00000405402.6
Gse1 coiled-coil protein
chr14_+_20999255 0.18 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr15_-_89751292 0.17 ENST00000300057.4
mesoderm posterior bHLH transcription factor 1
chr12_+_21372899 0.17 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr17_-_78360066 0.17 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chr5_-_75511213 0.16 ENST00000644445.1
ENST00000646302.1
ENST00000644912.1
ENST00000642809.1
ENST00000644377.1
ceramide transporter 1
chr16_+_67562514 0.16 ENST00000264010.10
ENST00000401394.6
ENST00000646771.1
CCCTC-binding factor
chr19_+_38789198 0.16 ENST00000314980.5
galectin 7B
chr5_+_75511756 0.16 ENST00000241436.8
DNA polymerase kappa
chr12_+_57460127 0.16 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr7_-_127392687 0.16 ENST00000393313.5
ENST00000619291.4
ENST00000265827.8
ENST00000434602.5
zinc finger protein 800
chr11_+_18322253 0.15 ENST00000453096.6
general transcription factor IIH subunit 1
chr15_+_41621492 0.15 ENST00000570161.6
MAX dimerization protein MGA
chr1_+_15736251 0.15 ENST00000294454.6
solute carrier family 25 member 34
chr12_+_113185702 0.15 ENST00000548278.2
RBPJ interacting and tubulin associated 1
chr17_+_27471999 0.15 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
kinase suppressor of ras 1
chr12_-_90955172 0.14 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr17_-_27893339 0.14 ENST00000460380.6
ENST00000379102.8
ENST00000508862.5
ENST00000582441.1
LYR motif containing 9
novel protein
chr11_+_122838492 0.14 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr17_-_63896568 0.14 ENST00000610991.1
ENST00000316193.13
ENST00000329882.8
chorionic somatomammotropin hormone 1
chr11_+_18322541 0.13 ENST00000534641.5
ENST00000265963.9
ENST00000525831.5
general transcription factor IIH subunit 1
chr2_+_209771972 0.13 ENST00000439458.5
ENST00000272845.10
unc-80 homolog, NALCN channel complex subunit
chr8_-_94895195 0.13 ENST00000308108.9
ENST00000396133.7
cyclin E2
chr1_+_154405193 0.13 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr12_+_103930332 0.12 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
heat shock protein 90 beta family member 1
chr11_+_111879482 0.12 ENST00000260276.8
ENST00000530214.5
ENST00000530799.5
chromosome 11 open reading frame 1
chr2_-_85668172 0.12 ENST00000428225.5
ENST00000519937.7
surfactant protein B
chr1_-_1074303 0.12 ENST00000453464.3
ring finger protein 223
chr7_-_27102669 0.12 ENST00000222718.7
homeobox A2
chr21_+_25734948 0.12 ENST00000400075.4
GA binding protein transcription factor subunit alpha
chr1_-_145927447 0.12 ENST00000632555.1
ENST00000369307.4
ENST00000583313.7
RNA binding motif protein 8A
chr12_+_50057548 0.12 ENST00000228468.8
ENST00000447966.7
acid sensing ion channel subunit 1
chr1_-_44017296 0.11 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
solute carrier family 6 member 9
chr5_+_57174016 0.11 ENST00000514387.6
ENST00000506184.7
GC-rich promoter binding protein 1
chr3_+_52777580 0.11 ENST00000273283.7
inter-alpha-trypsin inhibitor heavy chain 1
chrX_+_110002635 0.11 ENST00000372072.7
transmembrane protein 164
chr2_-_37231549 0.10 ENST00000234170.10
CCAAT enhancer binding protein zeta
chr7_+_69967464 0.10 ENST00000664521.1
activator of transcription and developmental regulator AUTS2
chr12_-_102478539 0.10 ENST00000424202.6
insulin like growth factor 1
chr1_-_225889143 0.09 ENST00000272134.5
left-right determination factor 1
chr12_-_110742929 0.09 ENST00000340766.9
protein phosphatase 1 catalytic subunit gamma
chr12_-_110742839 0.09 ENST00000551676.5
ENST00000550991.5
ENST00000335007.10
protein phosphatase 1 catalytic subunit gamma
chr2_+_209771814 0.09 ENST00000673951.1
ENST00000673920.1
unc-80 homolog, NALCN channel complex subunit
chr2_-_110534010 0.09 ENST00000437167.1
RANBP2 like and GRIP domain containing 6
chr21_-_25734887 0.08 ENST00000400094.5
ENST00000284971.8
ATP synthase peripheral stalk subunit F6
chr17_-_63873676 0.08 ENST00000613718.3
ENST00000392886.7
ENST00000345366.8
ENST00000336844.9
ENST00000560142.5
chorionic somatomammotropin hormone 2
chr2_+_37231633 0.08 ENST00000002125.9
ENST00000336237.10
ENST00000431821.5
NADH:ubiquinone oxidoreductase complex assembly factor 7
chr20_+_46029165 0.08 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
solute carrier family 12 member 5
chr21_-_25735026 0.08 ENST00000400099.5
ENST00000457143.6
ATP synthase peripheral stalk subunit F6
chr12_+_65279092 0.08 ENST00000646299.1
methionine sulfoxide reductase B3
chr5_+_57173948 0.08 ENST00000424459.7
GC-rich promoter binding protein 1
chr12_+_65278643 0.07 ENST00000355192.8
ENST00000308259.10
ENST00000540804.5
ENST00000535664.5
ENST00000541189.5
methionine sulfoxide reductase B3
chrX_+_124346544 0.07 ENST00000371139.9
SH2 domain containing 1A
chr12_+_65278919 0.06 ENST00000538045.5
ENST00000642411.1
ENST00000535239.5
ENST00000614640.4
methionine sulfoxide reductase B3
chr7_+_27242796 0.06 ENST00000496902.7
even-skipped homeobox 1
chr20_+_2536573 0.06 ENST00000358864.2
transmembrane channel like 2
chr14_+_75280078 0.06 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr11_-_119101814 0.06 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr9_+_4662281 0.06 ENST00000381883.5
phospholipid phosphatase 6
chr20_+_46029206 0.06 ENST00000243964.7
solute carrier family 12 member 5
chr2_-_61471062 0.06 ENST00000398571.7
ubiquitin specific peptidase 34
chr7_-_72336995 0.06 ENST00000329008.9
calneuron 1
chr14_+_52730154 0.05 ENST00000354586.5
ENST00000442123.6
serine/threonine/tyrosine interacting protein
chr12_+_48818478 0.05 ENST00000547818.5
ENST00000301050.7
ENST00000547392.5
calcium voltage-gated channel auxiliary subunit beta 3
chr10_-_75109085 0.04 ENST00000607131.5
dual specificity phosphatase 13
chr11_-_7796942 0.04 ENST00000329434.3
olfactory receptor family 5 subfamily P member 2
chr2_-_40453438 0.04 ENST00000455476.5
solute carrier family 8 member A1
chr11_-_129192291 0.04 ENST00000682385.1
Rho GTPase activating protein 32
chr11_-_129192198 0.04 ENST00000310343.13
Rho GTPase activating protein 32
chr12_+_18738102 0.04 ENST00000317658.5
capping actin protein of muscle Z-line subunit alpha 3
chr5_+_75512058 0.04 ENST00000514296.5
DNA polymerase kappa
chr5_-_34043205 0.04 ENST00000382065.8
ENST00000231338.7
C1q and TNF related 3
chr14_+_75278820 0.03 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr3_+_142596385 0.03 ENST00000457734.7
ENST00000483373.5
ENST00000475296.5
ENST00000495744.5
ENST00000476044.5
ENST00000461644.5
ENST00000464320.5
plastin 1
chr13_-_35855627 0.03 ENST00000379893.5
doublecortin like kinase 1
chr15_-_82647503 0.03 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr9_-_72365198 0.03 ENST00000376962.10
ENST00000376960.8
zinc finger AN1-type containing 5
chr6_+_39792298 0.03 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr13_-_35855758 0.02 ENST00000615680.4
doublecortin like kinase 1
chr12_+_48818763 0.02 ENST00000548279.5
ENST00000547230.5
calcium voltage-gated channel auxiliary subunit beta 3
chr14_+_90398159 0.02 ENST00000544280.6
calmodulin 1
chr17_+_59893046 0.02 ENST00000393021.7
ENST00000225577.9
ENST00000443572.6
ENST00000406116.7
ribosomal protein S6 kinase B1
chr8_+_86098901 0.02 ENST00000285393.4
ATPase H+ transporting V0 subunit d2
chr11_+_64306227 0.02 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr15_-_82647336 0.02 ENST00000617522.4
ENST00000684509.1
cytoplasmic polyadenylation element binding protein 1
chrM_+_10055 0.01 ENST00000361227.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
chr17_-_63918817 0.01 ENST00000458650.6
ENST00000351388.8
ENST00000342364.8
ENST00000617086.1
ENST00000323322.10
ENST00000392824.8
growth hormone 1
chorionic somatomammotropin hormone like 1
chr3_+_63819293 0.01 ENST00000295896.13
chromosome 3 open reading frame 49
chr5_-_60945008 0.01 ENST00000683052.1
ENST00000675229.1
ENST00000265038.10
ENST00000676185.1
ENST00000682217.1
ENST00000439176.6
ENST00000675042.2
ERCC excision repair 8, CSA ubiquitin ligase complex subunit
chr2_+_218607914 0.01 ENST00000417849.5
phospholipase C delta 4
chr15_-_82806054 0.00 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr1_+_206507520 0.00 ENST00000579436.7
Ras association domain family member 5
chr4_-_185535498 0.00 ENST00000284767.12
ENST00000284771.7
ENST00000284770.10
ENST00000620787.5
ENST00000629667.2
PDZ and LIM domain 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.4 1.1 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.2 0.6 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.2 0.5 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.5 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0051714 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.7 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.2 GO:0060913 cardiac cell fate determination(GO:0060913)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.4 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 1.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 1.1 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0060032 notochord regression(GO:0060032)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.6 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 1.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 2.1 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.6 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.0 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 1.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.3 2.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 1.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.9 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 2.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 2.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo