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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TBX5

Z-value: 0.65

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Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
ENSG00000089225.20 TBX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX5hg38_v1_chr12_-_114406133_1144061500.135.5e-01Click!

Activity profile of TBX5 motif

Sorted Z-values of TBX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_12616762 1.47 ENST00000464917.5
dehydrogenase/reductase 3
chr15_+_88638947 1.39 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr11_-_72674394 1.32 ENST00000418754.6
ENST00000334456.10
ENST00000542969.2
phosphodiesterase 2A
chr15_+_88639009 1.26 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr15_-_55289756 1.22 ENST00000336787.6
RAB27A, member RAS oncogene family
chr8_+_32548303 1.11 ENST00000650967.1
neuregulin 1
chr11_-_126062782 1.07 ENST00000531738.6
cell adhesion associated, oncogene regulated
chr1_-_153549238 1.00 ENST00000368713.8
S100 calcium binding protein A3
chr2_-_162318129 0.98 ENST00000679938.1
interferon induced with helicase C domain 1
chr17_+_79024142 0.94 ENST00000579760.6
ENST00000339142.6
C1q and TNF related 1
chr17_+_79024243 0.93 ENST00000311661.4
C1q and TNF related 1
chr8_+_32548210 0.92 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr21_+_42219123 0.88 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr2_-_2326378 0.88 ENST00000647618.1
myelin transcription factor 1 like
chr21_+_42219111 0.88 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr1_-_120051714 0.74 ENST00000579475.7
notch receptor 2
chr17_+_79025612 0.72 ENST00000392445.6
C1q and TNF related 1
chr2_-_175005357 0.70 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr5_+_114362043 0.70 ENST00000673685.1
potassium calcium-activated channel subfamily N member 2
chr5_+_114362286 0.69 ENST00000610748.4
ENST00000264773.7
potassium calcium-activated channel subfamily N member 2
chr21_+_42513834 0.68 ENST00000352133.3
solute carrier family 37 member 1
chr10_+_13100075 0.64 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr17_+_17042433 0.62 ENST00000651222.2
myosin phosphatase Rho interacting protein
chr16_+_56989479 0.62 ENST00000262510.10
NLR family CARD domain containing 5
chr8_+_122781621 0.61 ENST00000314393.6
zinc fingers and homeoboxes 2
chr11_-_16356538 0.61 ENST00000683767.1
SRY-box transcription factor 6
chr11_+_35176611 0.55 ENST00000279452.10
CD44 molecule (Indian blood group)
chr7_-_80919017 0.55 ENST00000265361.8
semaphorin 3C
chr17_+_76376581 0.54 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr2_+_240625237 0.52 ENST00000407714.1
G protein-coupled receptor 35
chr15_-_58065703 0.49 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr11_+_35176696 0.48 ENST00000528455.5
CD44 molecule (Indian blood group)
chr15_-_58065734 0.48 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr2_-_168913277 0.47 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr5_-_67196791 0.46 ENST00000256447.5
CD180 molecule
chr13_+_24270681 0.46 ENST00000343003.10
ENST00000399949.6
spermatogenesis associated 13
chr16_+_2537997 0.46 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr15_-_58065870 0.46 ENST00000537372.5
aldehyde dehydrogenase 1 family member A2
chrX_-_11665908 0.46 ENST00000337414.9
Rho GTPase activating protein 6
chrX_-_11427725 0.45 ENST00000380736.5
Rho GTPase activating protein 6
chr5_+_55024250 0.44 ENST00000231009.3
granzyme K
chrX_-_84502442 0.43 ENST00000297977.9
ENST00000506585.6
ENST00000373177.3
ENST00000449553.2
highly divergent homeobox
chr10_+_58269132 0.43 ENST00000333926.6
CDGSH iron sulfur domain 1
chr1_-_10982037 0.41 ENST00000377004.8
chromosome 1 open reading frame 127
chr19_-_38617912 0.41 ENST00000591517.5
mitogen-activated protein kinase kinase kinase kinase 1
chr9_+_137230757 0.41 ENST00000673865.1
ENST00000538474.5
ENST00000673835.1
ENST00000673953.1
ENST00000361134.2
solute carrier family 34 member 3
chr4_+_139301478 0.40 ENST00000296543.10
ENST00000398947.1
N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr1_-_72282457 0.40 ENST00000357731.10
neuronal growth regulator 1
chr2_-_144516154 0.39 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr19_-_54360949 0.39 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr1_+_26410809 0.39 ENST00000254231.4
ENST00000326279.11
lin-28 homolog A
chr19_-_38617928 0.39 ENST00000396857.7
ENST00000586296.5
mitogen-activated protein kinase kinase kinase kinase 1
chr11_+_35176575 0.38 ENST00000526000.6
CD44 molecule (Indian blood group)
chr19_+_7669080 0.38 ENST00000629642.1
resistin
chr14_+_22281097 0.38 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr6_+_45422564 0.38 ENST00000625924.1
RUNX family transcription factor 2
chr3_-_183162726 0.37 ENST00000265598.8
lysosomal associated membrane protein 3
chr11_+_35176639 0.37 ENST00000527889.6
CD44 molecule (Indian blood group)
chr16_-_69351778 0.36 ENST00000288025.4
transmembrane p24 trafficking protein 6
chr19_+_35138993 0.35 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr8_+_32548267 0.35 ENST00000356819.7
neuregulin 1
chr16_+_2988256 0.35 ENST00000573315.2
long intergenic non-protein coding RNA 514
chr7_-_27095972 0.35 ENST00000355633.5
ENST00000643460.2
homeobox A1
chr10_-_101229449 0.34 ENST00000370193.4
ladybird homeobox 1
chr6_+_45422485 0.34 ENST00000359524.7
RUNX family transcription factor 2
chr11_-_45907265 0.33 ENST00000449465.2
chromosome 11 open reading frame 94
chr22_-_31489528 0.33 ENST00000397525.5
eukaryotic translation initiation factor 4E nuclear import factor 1
chr6_+_30327259 0.32 ENST00000376659.9
ENST00000428555.1
tripartite motif containing 39
chr17_+_36103819 0.32 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr4_+_8580387 0.32 ENST00000382487.5
G protein-coupled receptor 78
chr2_+_68734773 0.32 ENST00000409202.8
Rho GTPase activating protein 25
chr19_-_47231191 0.32 ENST00000439096.3
BCL2 binding component 3
chr1_-_156816841 0.32 ENST00000368199.8
ENST00000392306.2
SH2 domain containing 2A
chr3_-_39192584 0.31 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr1_-_19923617 0.31 ENST00000375116.3
phospholipase A2 group IIE
chr4_+_80197493 0.30 ENST00000415738.3
PR/SET domain 8
chr2_+_68734861 0.30 ENST00000467265.5
Rho GTPase activating protein 25
chr1_-_156816738 0.29 ENST00000368198.7
SH2 domain containing 2A
chr3_-_134029914 0.29 ENST00000493729.5
ENST00000310926.11
solute carrier organic anion transporter family member 2A1
chr14_+_24310170 0.29 ENST00000530080.1
leukotriene B4 receptor 2
chr8_+_31639291 0.28 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr14_-_50830479 0.28 ENST00000382043.8
ninein
chr6_+_30326835 0.28 ENST00000440271.5
ENST00000376656.8
ENST00000396551.7
ENST00000428728.5
ENST00000396548.5
ENST00000428404.5
tripartite motif containing 39
chr7_-_76626127 0.28 ENST00000454397.1
POM121 and ZP3 fusion
chr11_-_123654581 0.28 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr3_-_24165548 0.28 ENST00000280696.9
thyroid hormone receptor beta
chr8_+_31639222 0.28 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr20_+_836052 0.27 ENST00000246100.3
family with sequence similarity 110 member A
chr2_+_209771972 0.27 ENST00000439458.5
ENST00000272845.10
unc-80 homolog, NALCN channel complex subunit
chr2_+_209771814 0.27 ENST00000673951.1
ENST00000673920.1
unc-80 homolog, NALCN channel complex subunit
chr14_+_21057822 0.27 ENST00000308227.2
ribonuclease A family member 8
chr12_+_107318395 0.27 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr17_-_35089212 0.27 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr8_+_1858750 0.26 ENST00000398560.2
Rho guanine nucleotide exchange factor 10
chr18_+_61333424 0.26 ENST00000262717.9
cadherin 20
chrX_+_70423031 0.26 ENST00000453994.6
ENST00000538649.5
ENST00000536730.5
glycerophosphodiester phosphodiesterase domain containing 2
chr2_+_201129318 0.26 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr1_-_150010675 0.25 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chrX_+_70423301 0.25 ENST00000374382.4
glycerophosphodiester phosphodiesterase domain containing 2
chr12_+_18738102 0.25 ENST00000317658.5
capping actin protein of muscle Z-line subunit alpha 3
chr7_+_97005538 0.25 ENST00000518156.3
distal-less homeobox 6
chr20_+_49982969 0.25 ENST00000244050.3
snail family transcriptional repressor 1
chr1_-_206921867 0.25 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr15_+_41621492 0.25 ENST00000570161.6
MAX dimerization protein MGA
chr16_-_50681328 0.25 ENST00000300590.7
sorting nexin 20
chr11_-_34513785 0.25 ENST00000257832.7
ENST00000429939.6
E74 like ETS transcription factor 5
chr11_-_41459592 0.25 ENST00000528697.6
ENST00000530763.5
leucine rich repeat containing 4C
chr4_-_156971769 0.24 ENST00000502773.6
platelet derived growth factor C
chr18_+_34493289 0.24 ENST00000682923.1
ENST00000596745.5
ENST00000283365.14
ENST00000315456.10
ENST00000598774.6
ENST00000684266.1
ENST00000683092.1
ENST00000683379.1
ENST00000684359.1
dystrobrevin alpha
chr15_+_36702009 0.24 ENST00000562489.1
CDAN1 interacting nuclease 1
chr11_+_131911396 0.24 ENST00000425719.6
ENST00000374784.5
neurotrimin
chr3_+_9649433 0.24 ENST00000353332.9
ENST00000420925.5
ENST00000296003.9
ENST00000351233.9
myotubularin related protein 14
chr17_+_3207539 0.24 ENST00000641322.1
ENST00000641732.2
olfactory receptor family 1 subfamily A member 1
chr16_-_4345904 0.24 ENST00000571941.5
presequence translocase associated motor 16
chr17_-_76537699 0.24 ENST00000293230.10
cytoglobin
chr17_+_58192723 0.23 ENST00000225371.6
eosinophil peroxidase
chr6_+_34236865 0.23 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
high mobility group AT-hook 1
chr12_-_52834307 0.23 ENST00000330553.6
keratin 79
chr5_+_140107777 0.23 ENST00000505703.2
ENST00000651386.1
purine rich element binding protein A
chr9_+_4662281 0.23 ENST00000381883.5
phospholipid phosphatase 6
chr18_+_34493428 0.22 ENST00000682483.1
dystrobrevin alpha
chrX_-_133415478 0.22 ENST00000370828.4
glypican 4
chr19_+_38304105 0.22 ENST00000588605.5
ENST00000301246.10
chromosome 19 open reading frame 33
chr20_+_31819302 0.22 ENST00000375994.6
myosin light chain kinase 2
chrX_+_96684712 0.22 ENST00000373049.8
diaphanous related formin 2
chrX_-_103832204 0.22 ENST00000674363.1
ENST00000674162.1
ENST00000674338.1
ENST00000674274.1
ENST00000674271.1
ENST00000674265.1
ENST00000674212.1
ENST00000674255.1
ENST00000674342.1
ENST00000674430.1
ENST00000243298.3
novel transcript
RAB9B, member RAS oncogene family
chr19_+_1000419 0.22 ENST00000234389.3
glutamate ionotropic receptor NMDA type subunit 3B
chr6_+_25652201 0.22 ENST00000612225.4
ENST00000377961.3
secretagogin, EF-hand calcium binding protein
chr1_+_148889403 0.22 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
phosphodiesterase 4D interacting protein
chr16_+_57186281 0.22 ENST00000564435.5
ENST00000562959.1
ENST00000568505.6
ENST00000394420.9
ENST00000537866.5
ring finger and SPRY domain containing 1
chr12_-_116276759 0.22 ENST00000548743.2
mediator complex subunit 13L
chr18_+_34493386 0.22 ENST00000679936.1
dystrobrevin alpha
chr5_+_141489150 0.22 ENST00000610789.1
protocadherin gamma subfamily C, 5
chr2_-_223837484 0.21 ENST00000446015.6
ENST00000409375.1
adaptor related protein complex 1 subunit sigma 3
chr6_+_25652272 0.21 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr12_+_30926716 0.21 ENST00000546076.6
ENST00000535215.5
ENST00000261177.10
tetraspanin 11
chr17_-_7394514 0.21 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chr20_+_31819348 0.21 ENST00000375985.5
myosin light chain kinase 2
chr2_-_118014035 0.21 ENST00000376300.7
coiled-coil domain containing 93
chr15_+_41621134 0.20 ENST00000566718.6
MAX dimerization protein MGA
chr1_+_202462730 0.20 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chr14_-_23408265 0.20 ENST00000405093.9
myosin heavy chain 6
chr15_+_81296913 0.20 ENST00000394652.6
interleukin 16
chr5_+_83471668 0.20 ENST00000342785.8
ENST00000343200.9
versican
chr17_-_7208325 0.20 ENST00000650120.1
ENST00000648760.1
discs large MAGUK scaffold protein 4
chr1_-_41918666 0.20 ENST00000372584.5
HIVEP zinc finger 3
chr15_+_88803468 0.20 ENST00000558207.5
aggrecan
chrX_+_103607906 0.20 ENST00000243286.7
ENST00000372627.10
transcription elongation factor A like 3
chr17_-_7394240 0.20 ENST00000576362.5
ENST00000571078.5
phospholipid scramblase 3
chr1_-_205455954 0.20 ENST00000495594.2
ENST00000629624.2
LEM domain containing 1
bladder cancer associated transcript 1
chr6_-_46015812 0.20 ENST00000544153.3
ENST00000339561.12
chloride intracellular channel 5
chr1_-_241357085 0.19 ENST00000366564.5
regulator of G protein signaling 7
chr2_-_118014125 0.19 ENST00000319432.9
coiled-coil domain containing 93
chr11_-_74949114 0.19 ENST00000527087.5
X-ray radiation resistance associated 1
chr19_+_35748549 0.19 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr1_+_46671821 0.19 ENST00000334122.5
ENST00000415500.1
testis expressed 38
chr19_-_10309783 0.19 ENST00000403352.1
ENST00000403903.7
zinc finger GATA like protein 1
chr1_-_183653307 0.19 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr22_-_21629991 0.18 ENST00000292778.11
ENST00000398873.4
YdjC chitooligosaccharide deacetylase homolog
chr2_+_120346130 0.18 ENST00000295228.4
inhibin subunit beta B
chr17_-_3916455 0.18 ENST00000225538.4
purinergic receptor P2X 1
chr11_-_95910665 0.18 ENST00000674610.1
ENST00000675660.1
myotubularin related protein 2
chr12_+_56118241 0.18 ENST00000551790.5
ENST00000552345.1
ENST00000257940.7
ENST00000551880.1
extended synaptotagmin 1
zinc finger CCCH-type containing 10
chr12_+_1629197 0.18 ENST00000397196.7
Wnt family member 5B
chrX_+_96684638 0.18 ENST00000355827.8
ENST00000373061.7
diaphanous related formin 2
chr12_-_102478539 0.18 ENST00000424202.6
insulin like growth factor 1
chr1_-_241357225 0.18 ENST00000366565.5
regulator of G protein signaling 7
chr1_-_241357171 0.18 ENST00000440928.6
regulator of G protein signaling 7
chr8_+_103819244 0.17 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr12_-_52434363 0.17 ENST00000252245.6
keratin 75
chr17_+_32487686 0.17 ENST00000584792.5
cyclin dependent kinase 5 regulatory subunit 1
chr19_+_48364361 0.17 ENST00000344846.7
synaptogyrin 4
chr12_-_120904337 0.17 ENST00000353487.7
signal peptide peptidase like 3
chr11_-_74949079 0.17 ENST00000528219.5
ENST00000684022.1
ENST00000531852.5
X-ray radiation resistance associated 1
chr11_+_450255 0.17 ENST00000308020.6
phosphatidylserine synthase 2
chr12_+_53252085 0.17 ENST00000329548.5
major facilitator superfamily domain containing 5
chr17_+_55266216 0.17 ENST00000573945.5
HLF transcription factor, PAR bZIP family member
chr11_-_40293102 0.17 ENST00000527150.5
leucine rich repeat containing 4C
chr3_+_167735704 0.17 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr1_-_1959974 0.16 ENST00000642590.1
cilia and flagella associated protein 74
chr17_-_15566276 0.16 ENST00000630868.1
CMT1A duplicated region transcript 1
chr2_-_24972032 0.16 ENST00000534855.5
DnaJ heat shock protein family (Hsp40) member C27
chr1_-_37034492 0.16 ENST00000373091.8
glutamate ionotropic receptor kainate type subunit 3
chr5_+_132673983 0.16 ENST00000622422.1
ENST00000231449.7
ENST00000350025.2
interleukin 4
chr11_-_74949142 0.16 ENST00000321448.12
ENST00000340360.10
X-ray radiation resistance associated 1
chr11_-_132943671 0.16 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr3_-_182985926 0.16 ENST00000487822.5
ENST00000460412.6
ENST00000469954.5
defective in cullin neddylation 1 domain containing 1
chr11_-_45917867 0.16 ENST00000378750.10
peroxisomal biogenesis factor 16
chr17_+_9162935 0.16 ENST00000436734.1
netrin 1
chr8_+_17027230 0.16 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr11_-_45918014 0.16 ENST00000525192.5
peroxisomal biogenesis factor 16
chr9_+_122375286 0.16 ENST00000373698.7
prostaglandin-endoperoxide synthase 1
chr19_-_49441508 0.16 ENST00000221485.8
solute carrier family 17 member 7
chr19_+_41443130 0.16 ENST00000378187.3
glutamate rich 4
chr5_+_126423122 0.16 ENST00000515200.5
GRAM domain containing 2B
chr12_-_48957365 0.16 ENST00000398092.4
ENST00000539611.1
novel protein
ADP ribosylation factor 3
chr12_+_104064520 0.16 ENST00000229330.9
host cell factor C2
chr2_-_223837553 0.16 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr5_-_115180037 0.16 ENST00000514154.1
ENST00000282369.7
tripartite motif containing 36
chr12_-_18738006 0.16 ENST00000266505.12
ENST00000543242.5
ENST00000539072.5
ENST00000541966.5
ENST00000648272.1
phospholipase C zeta 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 1.8 GO:0009720 detection of hormone stimulus(GO:0009720)
0.4 2.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 1.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 2.9 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.2 1.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 1.0 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 1.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.8 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.5 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.1 0.6 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.5 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.5 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.6 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 1.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.7 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.3 GO:0035803 egg coat formation(GO:0035803)
0.1 0.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.2 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.4 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.2 GO:0007314 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 1.0 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.3 GO:0019255 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.2 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.2 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.0 GO:1903937 response to acrylamide(GO:1903937)
0.0 0.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.6 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.5 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:0030221 basophil differentiation(GO:0030221)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.6 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.0 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150) negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.7 GO:0010165 response to X-ray(GO:0010165)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0038042 positive regulation of protein kinase A signaling(GO:0010739) dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.9 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 2.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 1.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.7 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 2.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.1 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.7 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.5 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 1.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 2.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.0 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling