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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TCF21

Z-value: 0.70

Motif logo

Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
ENSG00000118526.7 TCF21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg38_v1_chr6_+_133889105_133889120-0.154.6e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_224947030 4.29 ENST00000409592.7
dedicator of cytokinesis 10
chr6_-_159745186 3.61 ENST00000537657.5
superoxide dismutase 2
chr12_-_104958268 2.97 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr9_-_120926752 2.52 ENST00000373887.8
TNF receptor associated factor 1
chr12_+_77830886 2.27 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr5_-_170389349 1.74 ENST00000274629.9
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr1_-_150765735 1.64 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr18_+_24155938 1.56 ENST00000582229.1
calcium binding tyrosine phosphorylation regulated
chr1_+_78649818 1.53 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr22_-_50526337 1.49 ENST00000651490.1
ENST00000543927.6
thymidine phosphorylase
synthesis of cytochrome C oxidase 2
chr1_-_173207322 1.48 ENST00000281834.4
TNF superfamily member 4
chr22_-_50526130 1.47 ENST00000535425.5
ENST00000638598.2
synthesis of cytochrome C oxidase 2
chr17_+_79034185 1.27 ENST00000581774.5
C1q and TNF related 1
chr5_+_136028979 1.16 ENST00000442011.7
transforming growth factor beta induced
chr2_+_230416156 1.14 ENST00000427101.6
SP100 nuclear antigen
chr1_-_201469151 1.12 ENST00000367311.5
ENST00000367309.1
pleckstrin homology like domain family A member 3
chr2_+_230416239 1.04 ENST00000409824.5
ENST00000409341.5
ENST00000409112.5
SP100 nuclear antigen
chr5_+_50666917 1.03 ENST00000514342.6
poly(ADP-ribose) polymerase family member 8
chr6_-_27867581 1.01 ENST00000331442.5
H1.5 linker histone, cluster member
chr10_-_133357975 1.00 ENST00000447176.5
fucose mutarotase
chr10_-_133357674 1.00 ENST00000368551.1
fucose mutarotase
chr4_+_95051671 1.00 ENST00000440890.7
bone morphogenetic protein receptor type 1B
chr2_+_230416190 0.99 ENST00000340126.9
ENST00000432979.5
SP100 nuclear antigen
chr12_+_112125531 0.96 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr5_+_14143322 0.96 ENST00000344204.9
trio Rho guanine nucleotide exchange factor
chr5_-_59276109 0.95 ENST00000503258.5
phosphodiesterase 4D
chr1_+_212565334 0.94 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr1_+_155135344 0.93 ENST00000484157.5
solute carrier family 50 member 1
chrX_-_11427725 0.93 ENST00000380736.5
Rho GTPase activating protein 6
chr1_+_23743462 0.93 ENST00000609199.1
elongin A
chr5_-_151093566 0.89 ENST00000521001.1
TNFAIP3 interacting protein 1
chr18_+_58221535 0.88 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr5_+_50666950 0.86 ENST00000513738.5
ENST00000503665.5
ENST00000514067.6
ENST00000503046.5
poly(ADP-ribose) polymerase family member 8
chr6_+_31587185 0.83 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
leukocyte specific transcript 1
chr8_+_66043413 0.78 ENST00000522619.1
DnaJ heat shock protein family (Hsp40) member C5 beta
chr11_+_33039561 0.75 ENST00000334274.9
t-complex 11 like 1
chr9_+_116153783 0.74 ENST00000328252.4
pappalysin 1
chr7_-_41703062 0.74 ENST00000242208.5
inhibin subunit beta A
chr11_+_33039996 0.73 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr6_+_31587002 0.72 ENST00000376090.6
leukocyte specific transcript 1
chr11_+_122655712 0.70 ENST00000284273.6
ubiquitin associated and SH3 domain containing B
chr22_-_30246739 0.70 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr1_+_171185293 0.70 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr15_-_72231583 0.69 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr3_+_152835122 0.69 ENST00000305097.6
purinergic receptor P2Y1
chr3_+_184230373 0.69 ENST00000426955.6
von Willebrand factor A domain containing 5B2
chr7_-_22193728 0.66 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr1_+_172452885 0.65 ENST00000367725.4
chromosome 1 open reading frame 105
chr5_-_16936231 0.64 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr2_+_102104563 0.64 ENST00000409589.5
ENST00000409329.5
interleukin 1 receptor type 1
chr2_-_121736911 0.61 ENST00000451734.1
nucleolar protein interacting with the FHA domain of MKI67
chr10_+_88664439 0.61 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
lipase F, gastric type
chr16_+_56669807 0.58 ENST00000332374.5
metallothionein 1H
chr11_-_68213828 0.57 ENST00000405515.5
lysine methyltransferase 5B
chr1_-_30757767 0.57 ENST00000294507.4
lysosomal protein transmembrane 5
chr1_+_1033987 0.56 ENST00000651234.1
ENST00000652369.1
agrin
chr6_+_31587268 0.54 ENST00000396101.7
ENST00000490742.5
leukocyte specific transcript 1
chr22_+_21015027 0.49 ENST00000413302.6
ENST00000401443.5
purinergic receptor P2X 6
chr11_+_75151095 0.49 ENST00000289575.10
ENST00000525650.5
ENST00000454962.6
solute carrier organic anion transporter family member 2B1
chr11_+_59142811 0.49 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr16_+_56936654 0.48 ENST00000563911.5
homocysteine inducible ER protein with ubiquitin like domain 1
chr16_-_5097742 0.48 ENST00000587133.1
ENST00000458008.8
ENST00000427587.9
eukaryotic elongation factor 2 lysine methyltransferase
chr14_-_52791462 0.48 ENST00000650397.1
ENST00000554230.5
glucosamine-phosphate N-acetyltransferase 1
chr2_-_135047432 0.48 ENST00000392915.7
ENST00000637841.1
ENST00000414343.1
mitogen-activated protein kinase kinase kinase 19
chr18_+_59139864 0.47 ENST00000509791.7
ENST00000587834.6
ENST00000588875.2
SEC11 homolog C, signal peptidase complex subunit
chr22_+_37675629 0.47 ENST00000215909.10
galectin 1
chr6_-_28923932 0.47 ENST00000377199.4
ENST00000377194.7
tripartite motif containing 27
chr2_-_121736863 0.46 ENST00000285814.9
nucleolar protein interacting with the FHA domain of MKI67
chr1_-_167553745 0.46 ENST00000370509.5
cellular repressor of E1A stimulated genes 1
chr6_-_30690968 0.46 ENST00000376420.9
ENST00000376421.7
nurim
chr7_-_76627240 0.46 ENST00000275569.8
ENST00000310842.9
POM121 and ZP3 fusion
chr3_+_113947901 0.44 ENST00000330212.7
ENST00000498275.5
zinc finger DHHC-type palmitoyltransferase 23
chr14_-_81436447 0.44 ENST00000649389.1
ENST00000557055.5
stonin 2
chr17_+_7558712 0.44 ENST00000338784.9
ENST00000625791.2
TNF superfamily member 13
chr12_-_10723307 0.43 ENST00000279550.11
ENST00000228251.9
Y-box binding protein 3
chr17_+_7558774 0.43 ENST00000396545.4
TNF superfamily member 13
chr3_-_127590707 0.43 ENST00000296210.11
ENST00000355552.8
transmembrane protein adipocyte associated 1
chr10_-_122845850 0.42 ENST00000392790.6
CUB and zona pellucida like domains 1
chr8_+_143213192 0.42 ENST00000622500.2
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr19_-_4535221 0.42 ENST00000381848.7
ENST00000586133.1
perilipin 5
chr3_+_52211442 0.42 ENST00000459884.1
5'-aminolevulinate synthase 1
chr7_-_76626127 0.41 ENST00000454397.1
POM121 and ZP3 fusion
chr4_-_4542034 0.41 ENST00000306200.7
syntaxin 18
chr1_+_11736120 0.41 ENST00000400895.6
ENST00000314340.10
ENST00000376629.8
ENST00000376627.6
ENST00000452018.6
ENST00000510878.1
angiotensin II receptor associated protein
chr8_-_20183090 0.41 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr1_-_150697128 0.40 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chr17_+_4583998 0.40 ENST00000338859.8
smoothelin like 2
chr2_+_6877768 0.40 ENST00000382040.4
radical S-adenosyl methionine domain containing 2
chr16_-_81220370 0.40 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chr2_+_232697362 0.40 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr18_-_49849827 0.39 ENST00000592688.1
myosin VB
chr20_+_836052 0.39 ENST00000246100.3
family with sequence similarity 110 member A
chrX_-_109625161 0.39 ENST00000372101.3
potassium voltage-gated channel subfamily E regulatory subunit 5
chr9_+_122375286 0.39 ENST00000373698.7
prostaglandin-endoperoxide synthase 1
chr1_+_11736068 0.39 ENST00000376637.7
angiotensin II receptor associated protein
chr20_-_46689412 0.39 ENST00000372102.3
ENST00000372114.4
TP53 regulating kinase
chr8_-_20183127 0.38 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr19_+_11541125 0.38 ENST00000587087.5
calponin 1
chr4_-_46909206 0.38 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr11_-_615570 0.37 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr3_+_142723999 0.37 ENST00000476941.6
ENST00000273482.10
transient receptor potential cation channel subfamily C member 1
chr6_+_30617825 0.36 ENST00000259873.5
mitochondrial ribosomal protein S18B
chr13_+_50909983 0.36 ENST00000643682.1
ENST00000642721.1
ENST00000616907.2
ribonuclease H2 subunit B
chr15_+_89243945 0.36 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FA complementation group I
chr18_+_57352541 0.36 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr11_-_74949114 0.36 ENST00000527087.5
X-ray radiation resistance associated 1
chr19_-_633500 0.36 ENST00000588649.7
RNA polymerase mitochondrial
chr11_-_102625332 0.36 ENST00000260228.3
matrix metallopeptidase 20
chr8_+_25459190 0.35 ENST00000380665.3
ENST00000330560.8
cell division cycle associated 2
chr22_-_22508702 0.35 ENST00000626650.3
zinc finger protein 280B
chr1_-_205422050 0.35 ENST00000367153.9
LEM domain containing 1
chr6_-_35797313 0.34 ENST00000259938.7
ENST00000616014.3
colipase
chr11_+_34105582 0.34 ENST00000531159.6
ENST00000257829.8
N-acetyltransferase 10
chr14_-_44961889 0.34 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
kelch like family member 28
chr19_+_46298382 0.34 ENST00000244303.10
ENST00000533145.5
ENST00000472815.5
hypoxia inducible factor 3 subunit alpha
chr10_+_96832252 0.34 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
ligand dependent nuclear receptor corepressor
chr7_+_100101632 0.34 ENST00000359593.9
adaptor related protein complex 4 subunit mu 1
chr20_-_1329131 0.33 ENST00000360779.4
syndecan binding protein 2
chr7_+_100101556 0.32 ENST00000438383.5
ENST00000429084.5
ENST00000439416.5
adaptor related protein complex 4 subunit mu 1
chr6_+_54083423 0.32 ENST00000460844.6
ENST00000370876.6
muscular LMNA interacting protein
chr12_-_6851245 0.32 ENST00000540683.1
ENST00000229265.10
ENST00000535406.5
ENST00000422785.7
ENST00000538862.7
cell division cycle associated 3
chr17_-_41149823 0.31 ENST00000343246.6
keratin associated protein 4-5
chr10_+_35126923 0.31 ENST00000374726.7
cAMP responsive element modulator
chr11_+_2382460 0.31 ENST00000492627.5
CD81 molecule
chr5_-_170389634 0.31 ENST00000521859.1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr17_-_7394514 0.31 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chr17_+_6444441 0.31 ENST00000250056.12
ENST00000571373.5
ENST00000570337.6
ENST00000572595.6
ENST00000572447.6
ENST00000576056.5
PICALM interacting mitotic regulator
chr11_+_65386611 0.31 ENST00000531296.1
ENST00000533782.5
ENST00000355991.9
ENST00000317568.10
ENST00000416776.6
ENST00000526201.1
FERM domain containing 8
chr1_-_230869564 0.31 ENST00000470540.5
chromosome 1 open reading frame 198
chr13_-_49936486 0.31 ENST00000378195.6
SPRY domain containing 7
chrX_+_70290077 0.30 ENST00000374403.4
kinesin family member 4A
chr3_+_167735704 0.30 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr2_-_55049184 0.30 ENST00000357376.7
reticulon 4
chr6_-_39229465 0.29 ENST00000359534.4
potassium two pore domain channel subfamily K member 5
chr11_-_30016945 0.29 ENST00000328224.7
potassium voltage-gated channel subfamily A member 4
chr7_+_142800957 0.29 ENST00000466254.1
T cell receptor beta constant 2
chr22_+_49853801 0.29 ENST00000216268.6
zinc finger BED-type containing 4
chr11_+_59142728 0.29 ENST00000528737.5
FAM111 trypsin like peptidase A
chr11_-_74949142 0.28 ENST00000321448.12
ENST00000340360.10
X-ray radiation resistance associated 1
chr9_+_34646589 0.28 ENST00000450095.6
galactose-1-phosphate uridylyltransferase
chr17_+_2593628 0.28 ENST00000397195.10
platelet activating factor acetylhydrolase 1b regulatory subunit 1
chr11_-_74949079 0.28 ENST00000528219.5
ENST00000684022.1
ENST00000531852.5
X-ray radiation resistance associated 1
chr19_-_50719761 0.28 ENST00000293441.6
SH3 and multiple ankyrin repeat domains 1
chr5_-_892533 0.27 ENST00000483173.5
bromodomain containing 9
chr19_-_4867649 0.27 ENST00000592528.5
ENST00000589494.1
ENST00000221957.9
perilipin 3
chr19_-_45076465 0.27 ENST00000303809.7
zinc finger protein 296
chr3_-_124934735 0.27 ENST00000478191.1
ENST00000616727.4
mucin 13, cell surface associated
chr9_+_34646654 0.27 ENST00000378842.8
galactose-1-phosphate uridylyltransferase
chr16_+_30372291 0.27 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr5_+_177304571 0.27 ENST00000503853.1
PRELI domain containing 1
chr13_-_49936298 0.27 ENST00000613924.1
ENST00000361840.8
SPRY domain containing 7
chr18_+_158513 0.27 ENST00000400266.7
ENST00000580410.5
ENST00000261601.8
ENST00000383589.6
ubiquitin specific peptidase 14
chr19_-_4867678 0.27 ENST00000585479.5
perilipin 3
chr2_-_218671975 0.27 ENST00000295704.7
ring finger protein 25
chr6_-_73452253 0.27 ENST00000370318.5
ENST00000370315.4
cyclic GMP-AMP synthase
chr2_-_213151590 0.26 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr4_+_8182066 0.26 ENST00000508641.2
SH3 domain and tetratricopeptide repeats 1
chr11_-_796185 0.26 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr1_+_153628393 0.26 ENST00000368696.3
ENST00000292169.6
ENST00000436839.1
S100 calcium binding protein A1
chr4_-_46909235 0.26 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr17_-_7394800 0.26 ENST00000574401.5
phospholipid scramblase 3
chr10_-_50885619 0.26 ENST00000373997.8
APOBEC1 complementation factor
chr3_+_3799424 0.26 ENST00000319331.4
leucine rich repeat neuronal 1
chr6_-_11382247 0.26 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr2_-_17800195 0.26 ENST00000402989.5
ENST00000428868.1
structural maintenance of chromosomes 6
chr6_-_25830557 0.26 ENST00000468082.1
solute carrier family 17 member 1
chr17_+_41249687 0.26 ENST00000334109.3
keratin associated protein 9-4
chrX_+_104566193 0.26 ENST00000372582.6
interleukin 1 receptor accessory protein like 2
chr1_-_165445220 0.25 ENST00000619224.1
retinoid X receptor gamma
chr19_-_45322867 0.25 ENST00000221476.4
creatine kinase, M-type
chr16_+_1972035 0.25 ENST00000568546.6
ENST00000615855.4
transducin beta like 3
chr4_+_37891060 0.25 ENST00000261439.9
ENST00000508802.5
ENST00000402522.1
TBC1 domain family member 1
chr19_+_6531018 0.25 ENST00000245817.5
TNF superfamily member 9
chr11_-_615921 0.25 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr1_-_15944348 0.25 ENST00000444358.1
zinc finger and BTB domain containing 17
chr2_+_68157877 0.24 ENST00000263657.7
partner of NOB1 homolog
chr8_+_38728186 0.24 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chr15_-_76012390 0.24 ENST00000394907.8
neuregulin 4
chr15_-_42457513 0.24 ENST00000565611.5
ENST00000263805.8
zinc finger protein 106
chr17_-_39927549 0.23 ENST00000579695.5
ENST00000304046.7
ORMDL sphingolipid biosynthesis regulator 3
chr1_-_165445088 0.23 ENST00000359842.10
retinoid X receptor gamma
chr20_-_3682218 0.23 ENST00000379861.8
ADAM metallopeptidase domain 33
chr4_-_20984011 0.23 ENST00000382149.9
potassium voltage-gated channel interacting protein 4
chr10_-_50885656 0.23 ENST00000374001.6
ENST00000395489.6
ENST00000282641.6
ENST00000395495.5
ENST00000373995.7
ENST00000414883.1
APOBEC1 complementation factor
chr2_+_64453969 0.23 ENST00000464281.5
galectin like
chr17_-_15260752 0.23 ENST00000676329.1
ENST00000675551.1
ENST00000644020.1
ENST00000674947.1
peripheral myelin protein 22
chr11_-_5301946 0.23 ENST00000380224.2
olfactory receptor family 51 subfamily B member 4
chr22_+_20917398 0.22 ENST00000354336.8
CRK like proto-oncogene, adaptor protein
chr17_-_81683659 0.22 ENST00000574938.5
ENST00000570561.5
ENST00000573392.5
ENST00000576135.5
ENST00000573715.2
ADP ribosylation factor like GTPase 16
chr2_+_118088432 0.22 ENST00000245787.9
insulin induced gene 2
chr1_+_21977014 0.22 ENST00000337107.11
chymotrypsin like elastase 3B
chr13_-_103066411 0.22 ENST00000245312.5
solute carrier family 10 member 2
chr10_-_26860975 0.22 ENST00000376166.5
ENST00000346832.10
ENST00000376138.7
ENST00000536334.5
ENST00000490841.6
ENST00000376137.8
abl interactor 1
chr1_-_160711803 0.22 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48 molecule
chr12_+_113221429 0.22 ENST00000551096.5
ENST00000551099.5
ENST00000552897.5
ENST00000550785.5
ENST00000549279.1
ENST00000335509.11
two pore segment channel 1
chr11_+_74949241 0.22 ENST00000610881.4
ENST00000530257.5
ENST00000526361.1
ENST00000532972.5
ENST00000263672.11
signal peptidase complex subunit 2
chr19_-_45076504 0.21 ENST00000622376.1
zinc finger protein 296
chr15_+_65045377 0.21 ENST00000334287.3
solute carrier family 51 subunit beta
chr17_-_4263847 0.21 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr2_+_29115367 0.21 ENST00000320081.10
CAP-Gly domain containing linker protein family member 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.6 3.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.5 1.6 GO:0034769 basement membrane disassembly(GO:0034769)
0.5 1.5 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 2.0 GO:1903413 cellular response to bile acid(GO:1903413)
0.3 0.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 0.9 GO:0042946 glucoside transport(GO:0042946) glycoside transport(GO:1901656)
0.3 0.9 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 4.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.7 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 0.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 0.6 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 0.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 1.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.9 GO:0035803 egg coat formation(GO:0035803)
0.1 1.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 3.0 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 3.0 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 0.8 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 1.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 2.0 GO:0060180 female mating behavior(GO:0060180)
0.1 0.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.4 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0032439 endosome localization(GO:0032439)
0.1 0.7 GO:0032962 negative regulation of norepinephrine secretion(GO:0010700) regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.4 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.5 GO:0035900 response to isolation stress(GO:0035900)
0.1 0.5 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.4 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.2 GO:0071283 regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283)
0.1 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.3 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.2 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 1.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.3 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.5 GO:1903071 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.3 GO:0050893 sensory processing(GO:0050893)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.7 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.7 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 1.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 2.5 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.7 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.7 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.9 GO:0010165 response to X-ray(GO:0010165)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 1.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.5 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.2 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0097229 sperm end piece(GO:0097229)
0.3 0.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.7 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 3.2 GO:0030870 Mre11 complex(GO:0030870)
0.2 1.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.5 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.8 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.9 GO:0070449 elongin complex(GO:0070449)
0.1 1.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 2.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.6 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 3.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.0 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030686 90S preribosome(GO:0030686)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0016154 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.4 3.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 2.0 GO:0042806 fucose binding(GO:0042806)
0.3 0.9 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.3 3.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 0.8 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 1.5 GO:0004645 phosphorylase activity(GO:0004645)
0.2 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 3.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.9 GO:0035473 lipase binding(GO:0035473)
0.1 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.8 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.5 GO:0030395 lactose binding(GO:0030395)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 0.9 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.7 GO:0031685 G-protein coupled adenosine receptor activity(GO:0001609) adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.7 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 2.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 1.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 1.6 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.9 PID FOXO PATHWAY FoxO family signaling
0.0 2.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 3.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 2.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 4.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters