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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TCF7L1

Z-value: 0.73

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
ENSG00000152284.5 TCF7L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg38_v1_chr2_+_85133376_851334740.154.8e-01Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr13_-_71867192 1.72 ENST00000611519.4
ENST00000620444.4
ENST00000613252.5
dachshund family transcription factor 1
chr4_-_185956348 1.48 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr1_+_99646025 1.29 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr1_+_60865259 1.19 ENST00000371191.5
nuclear factor I A
chr2_-_207166818 0.94 ENST00000423015.5
Kruppel like factor 7
chr16_-_46831043 0.91 ENST00000565112.1
chromosome 16 open reading frame 87
chr2_+_69013170 0.85 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr2_+_227813834 0.74 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr14_+_23377136 0.67 ENST00000382809.2
CKLF like MARVEL transmembrane domain containing 5
chr2_-_207167220 0.66 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chrX_+_72069659 0.62 ENST00000631375.1
NHS like 2
chr5_+_175861628 0.62 ENST00000509837.5
complexin 2
chr10_+_123135938 0.60 ENST00000357878.7
H6 family homeobox 3
chr3_-_15797930 0.60 ENST00000683139.1
ankyrin repeat domain 28
chr3_-_65622073 0.58 ENST00000621418.4
ENST00000611645.4
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr9_+_125748175 0.57 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr2_+_11539833 0.57 ENST00000263834.9
growth regulating estrogen receptor binding 1
chr15_+_62066975 0.56 ENST00000355522.5
C2 calcium dependent domain containing 4A
chrX_-_40097403 0.55 ENST00000397354.7
BCL6 corepressor
chr20_+_57391388 0.54 ENST00000356208.10
ENST00000440234.6
RNA binding motif protein 38
chr14_+_20768393 0.53 ENST00000326783.4
epididymal protein 3B
chr10_+_69802424 0.52 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
collagen type XIII alpha 1 chain
chr5_+_171419635 0.51 ENST00000274625.6
fibroblast growth factor 18
chr2_+_69013282 0.48 ENST00000409829.7
ANTXR cell adhesion molecule 1
chr10_-_86957582 0.46 ENST00000372027.10
multimerin 2
chr10_+_69801874 0.46 ENST00000357811.8
collagen type XIII alpha 1 chain
chr20_+_32010429 0.45 ENST00000452892.3
ENST00000262659.12
CCM2 like scaffold protein
chr14_+_74763308 0.45 ENST00000325680.12
ENST00000552421.5
YLP motif containing 1
chr6_-_11778781 0.44 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr15_+_81000913 0.43 ENST00000267984.4
talin rod domain containing 1
chr13_+_31945826 0.42 ENST00000647500.1
FRY microtubule binding protein
chr10_+_52314272 0.42 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr1_-_93614091 0.41 ENST00000370247.7
BCAR3 adaptor protein, NSP family member
chr11_-_62707413 0.41 ENST00000360796.10
ENST00000449636.6
BSCL2 lipid droplet biogenesis associated, seipin
chr2_+_69013379 0.41 ENST00000409349.7
ANTXR cell adhesion molecule 1
chr17_+_82458174 0.40 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr2_+_69013414 0.39 ENST00000681816.1
ENST00000482235.2
ANTXR cell adhesion molecule 1
chr2_+_15940537 0.39 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr10_+_69801892 0.39 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr1_+_100351698 0.38 ENST00000644676.1
cell division cycle 14A
chr10_+_113553039 0.38 ENST00000351270.4
hyaluronan binding protein 2
chr17_+_82458649 0.37 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
nuclear prelamin A recognition factor
chr10_-_14572123 0.37 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
family with sequence similarity 107 member B
chr1_+_81800368 0.37 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr19_-_47545261 0.36 ENST00000595558.1
ENST00000263351.9
zinc finger protein 541
chr11_-_89491320 0.36 ENST00000534731.5
ENST00000527626.5
ENST00000525196.5
ENST00000263317.9
NADPH oxidase 4
chr12_+_55931148 0.35 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
diacylglycerol kinase alpha
chr9_+_113463697 0.35 ENST00000317613.10
regulator of G protein signaling 3
chr11_-_62707581 0.35 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2 lipid droplet biogenesis associated, seipin
chr3_+_137764296 0.34 ENST00000306087.3
SRY-box transcription factor 14
chr4_-_156970903 0.34 ENST00000422544.2
platelet derived growth factor C
chr11_-_88175432 0.34 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38, member RAS oncogene family
chr7_-_140176970 0.34 ENST00000397560.7
lysine demethylase 7A
chr19_-_11339573 0.33 ENST00000222120.8
RAB3D, member RAS oncogene family
chr17_+_82458733 0.33 ENST00000309794.16
ENST00000577410.2
nuclear prelamin A recognition factor
chr16_-_4800470 0.32 ENST00000592019.1
ENST00000586153.1
rogdi atypical leucine zipper
chr8_-_143973520 0.32 ENST00000356346.7
plectin
chr10_-_24952573 0.32 ENST00000376378.5
ENST00000376376.3
ENST00000320152.11
phosphoribosyl transferase domain containing 1
chr3_+_124094663 0.31 ENST00000460856.5
ENST00000240874.7
kalirin RhoGEF kinase
chr17_+_74432079 0.30 ENST00000392627.7
ENST00000392628.7
ENST00000582473.2
G protein-coupled receptor class C group 5 member C
chrX_-_100928903 0.30 ENST00000372956.3
XK related X-linked
chr6_-_32178080 0.30 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr14_-_34875348 0.27 ENST00000360310.6
bromodomain adjacent to zinc finger domain 1A
chr20_+_18813777 0.27 ENST00000377428.4
SCP2 sterol binding domain containing 1
chr14_-_34874887 0.27 ENST00000382422.6
bromodomain adjacent to zinc finger domain 1A
chr2_+_69013337 0.27 ENST00000463335.2
ANTXR cell adhesion molecule 1
chr10_+_7703340 0.26 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr17_-_7394800 0.26 ENST00000574401.5
phospholipid scramblase 3
chr22_-_38084093 0.26 ENST00000681075.1
solute carrier family 16 member 8
chr5_-_176537361 0.26 ENST00000274811.9
ring finger protein 44
chr8_-_33567118 0.26 ENST00000256257.2
ring finger protein 122
chr16_-_46831134 0.26 ENST00000394806.6
ENST00000285697.9
chromosome 16 open reading frame 87
chr7_+_116210501 0.25 ENST00000455989.1
ENST00000358204.9
testin LIM domain protein
chr17_-_7394514 0.25 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chr7_+_116672187 0.25 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr12_+_8914464 0.25 ENST00000544916.6
polyhomeotic homolog 1
chr18_+_3450036 0.24 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGFB induced factor homeobox 1
chr17_-_7394240 0.24 ENST00000576362.5
ENST00000571078.5
phospholipid scramblase 3
chr14_-_73027077 0.24 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr7_-_151814636 0.23 ENST00000652047.1
ENST00000650858.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr14_+_105474781 0.23 ENST00000550577.5
ENST00000538259.2
ENST00000329146.9
cysteine rich protein 2
chr15_-_55588337 0.23 ENST00000563719.4
pygopus family PHD finger 1
chr1_+_182839338 0.22 ENST00000367549.4
DExH-box helicase 9
chr14_-_73027117 0.22 ENST00000318876.9
zinc finger FYVE-type containing 1
chr7_-_151814668 0.22 ENST00000651764.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr3_+_52779916 0.21 ENST00000537050.5
inter-alpha-trypsin inhibitor heavy chain 1
chr18_+_32190015 0.21 ENST00000581447.1
meprin A subunit beta
chr18_+_32190033 0.21 ENST00000269202.11
meprin A subunit beta
chr3_-_126056786 0.21 ENST00000383598.6
solute carrier family 41 member 3
chr10_+_22316445 0.21 ENST00000448361.5
COMM domain containing 3
chr12_+_53097656 0.21 ENST00000301464.4
insulin like growth factor binding protein 6
chr15_-_82046119 0.20 ENST00000558133.1
mex-3 RNA binding family member B
chr10_+_7703300 0.20 ENST00000358415.9
inter-alpha-trypsin inhibitor heavy chain 2
chr20_+_62817023 0.20 ENST00000649368.1
collagen type IX alpha 3 chain
chr3_+_138348592 0.19 ENST00000621127.4
ENST00000494949.5
muscle RAS oncogene homolog
chr6_+_108559742 0.19 ENST00000343882.10
forkhead box O3
chr20_-_17531366 0.19 ENST00000377873.8
beaded filament structural protein 1
chr10_+_22316375 0.19 ENST00000376836.8
ENST00000456711.5
ENST00000444869.5
ENST00000475460.6
ENST00000602390.5
ENST00000489125.2
COMM domain containing 3
COMMD3-BMI1 readthrough
chr7_+_80646305 0.19 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr15_-_82045998 0.18 ENST00000329713.5
mex-3 RNA binding family member B
chr8_+_119067239 0.18 ENST00000332843.3
collectin subfamily member 10
chr13_+_39038347 0.18 ENST00000379599.6
ENST00000379600.8
NHL repeat containing 3
chr5_+_67004618 0.18 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chrX_+_101391202 0.18 ENST00000471855.1
ribosomal protein L36a
chr4_-_5893075 0.18 ENST00000324989.12
collapsin response mediator protein 1
chr13_+_39038292 0.18 ENST00000470258.5
NHL repeat containing 3
chr9_-_120926752 0.18 ENST00000373887.8
TNF receptor associated factor 1
chr17_+_77451244 0.18 ENST00000591088.5
septin 9
chr19_+_10960955 0.17 ENST00000642628.1
ENST00000643296.1
ENST00000647230.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr5_-_115180037 0.17 ENST00000514154.1
ENST00000282369.7
tripartite motif containing 36
chrX_+_101390976 0.17 ENST00000392994.7
ribosomal protein L36a
chrX_+_101391000 0.17 ENST00000553110.8
ENST00000409338.5
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr2_+_233712905 0.17 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr19_+_10960976 0.17 ENST00000646510.1
ENST00000429416.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr10_-_102432565 0.17 ENST00000369937.5
CUE domain containing 2
chr9_-_35650902 0.17 ENST00000259608.8
ENST00000618781.1
signaling threshold regulating transmembrane adaptor 1
chr15_-_78811415 0.16 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr5_+_66828762 0.16 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr14_-_23155302 0.16 ENST00000529705.6
solute carrier family 7 member 8
chr2_+_178320228 0.16 ENST00000315022.2
oxysterol binding protein like 6
chr11_-_65614195 0.16 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr6_-_11779606 0.16 ENST00000506810.1
androgen dependent TFPI regulating protein
chr12_+_32107296 0.16 ENST00000551086.1
BICD cargo adaptor 1
chrX_+_101390824 0.16 ENST00000427805.6
ENST00000614077.4
ribosomal protein L36a
chr17_+_32486975 0.16 ENST00000313401.4
cyclin dependent kinase 5 regulatory subunit 1
chr1_-_6419903 0.16 ENST00000377836.8
ENST00000487437.5
ENST00000489730.1
ENST00000377834.8
hes family bHLH transcription factor 2
chr12_+_8914525 0.16 ENST00000543824.5
polyhomeotic homolog 1
chr9_-_72365198 0.15 ENST00000376962.10
ENST00000376960.8
zinc finger AN1-type containing 5
chr5_-_59039454 0.15 ENST00000358923.10
phosphodiesterase 4D
chr16_-_15643024 0.15 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr8_+_32721823 0.15 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr16_-_18801424 0.15 ENST00000546206.6
ENST00000562819.5
ENST00000304414.12
ENST00000562234.2
ENST00000567078.2
ADP ribosylation factor like GTPase 6 interacting protein 1
novel protein
chr9_+_100427254 0.15 ENST00000374885.5
Myb/SANT DNA binding domain containing 3
chr18_+_3449817 0.15 ENST00000407501.6
TGFB induced factor homeobox 1
chrX_+_136147465 0.15 ENST00000651929.2
four and a half LIM domains 1
chr6_+_154995258 0.15 ENST00000682666.1
TIAM Rac1 associated GEF 2
chr19_+_10960917 0.15 ENST00000643549.1
ENST00000642726.1
ENST00000646484.1
ENST00000644737.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr17_-_40937641 0.15 ENST00000209718.8
keratin 23
chr8_-_42501224 0.14 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr20_-_675793 0.14 ENST00000488788.2
ENST00000246104.7
novel protein
scratch family transcriptional repressor 2
chr8_-_94896660 0.14 ENST00000520509.5
cyclin E2
chr7_+_100733576 0.14 ENST00000613979.5
ENST00000620596.4
zonadhesin
chr10_+_11164961 0.13 ENST00000399850.7
ENST00000417956.6
CUGBP Elav-like family member 2
chr15_-_64703199 0.13 ENST00000559753.1
ENST00000560258.6
ENST00000559912.2
ENST00000326005.10
ornithine decarboxylase antizyme 2
chrX_-_136880715 0.13 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr17_+_37491464 0.13 ENST00000613659.1
dual specificity phosphatase 14
chr9_-_72364504 0.13 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chrX_+_126819720 0.13 ENST00000371125.4
proline rich 32
chr2_-_80304274 0.12 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
leucine rich repeat transmembrane neuronal 1
chr17_-_40937445 0.12 ENST00000436344.7
ENST00000485751.1
keratin 23
chr15_-_101252040 0.12 ENST00000254190.4
chondroitin sulfate synthase 1
chr14_-_20454741 0.12 ENST00000206542.9
ENST00000553640.3
O-sialoglycoprotein endopeptidase
chr7_+_80646436 0.12 ENST00000419819.2
CD36 molecule
chr1_-_242449478 0.12 ENST00000427495.5
phospholipase D family member 5
chr17_+_50548041 0.12 ENST00000634597.1
spermatogenesis associated 20
chr14_+_75280078 0.12 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chrX_-_154371210 0.12 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr17_+_59220446 0.12 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr14_-_22982258 0.11 ENST00000555074.1
ENST00000361265.8
novel protein
ajuba LIM protein
chr6_-_89217339 0.11 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr14_+_20455185 0.11 ENST00000555414.5
ENST00000553681.5
apurinic/apyrimidinic endodeoxyribonuclease 1
chr3_+_141387801 0.11 ENST00000514251.5
zinc finger and BTB domain containing 38
chr6_+_95577465 0.11 ENST00000369293.6
ENST00000683151.1
ENST00000358812.9
mannosidase endo-alpha
chr7_+_116672357 0.11 ENST00000456159.1
MET proto-oncogene, receptor tyrosine kinase
chr15_-_89221558 0.11 ENST00000268125.10
retinaldehyde binding protein 1
chr13_+_23570370 0.11 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr14_+_20745880 0.11 ENST00000326842.3
epididymal protein 3A
chr17_+_59155726 0.11 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chrX_+_136147556 0.11 ENST00000651089.1
ENST00000420362.5
four and a half LIM domains 1
chr8_+_30095649 0.11 ENST00000518192.5
leptin receptor overlapping transcript like 1
chr12_+_70366277 0.10 ENST00000258111.5
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr19_-_48363914 0.10 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chr9_-_27005659 0.10 ENST00000380055.6
leucine rich repeat containing 19
chr1_+_35883189 0.10 ENST00000674304.1
ENST00000373204.6
ENST00000674426.1
argonaute RISC component 1
chr10_+_113126670 0.10 ENST00000369389.6
transcription factor 7 like 2
chr13_+_75760362 0.10 ENST00000534657.5
LIM domain 7
chr14_-_22982544 0.10 ENST00000262713.7
ajuba LIM protein
chr13_+_75760659 0.10 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr1_-_42958836 0.10 ENST00000372500.4
ENST00000674765.1
ENST00000460369.3
ENST00000426263.10
solute carrier family 2 member 1
chr1_+_154272589 0.09 ENST00000457918.6
ENST00000483970.6
ENST00000328703.12
ENST00000435087.1
ENST00000532105.1
HCLS1 associated protein X-1
chr17_+_47522931 0.09 ENST00000525007.5
ENST00000530173.6
aminopeptidase puromycin sensitive
chr3_+_141368497 0.09 ENST00000321464.7
zinc finger and BTB domain containing 38
chr8_+_30095400 0.09 ENST00000321250.13
ENST00000518001.1
ENST00000520682.5
ENST00000442880.6
ENST00000523116.5
leptin receptor overlapping transcript like 1
chr2_+_176129680 0.09 ENST00000429017.2
ENST00000313173.6
homeobox D8
chr19_-_48364034 0.09 ENST00000435956.7
transmembrane protein 143
chr9_+_136327526 0.09 ENST00000440944.6
G protein signaling modulator 1
chr17_+_59565598 0.08 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr7_-_19773569 0.08 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
transmembrane protein 196
chr13_+_75760431 0.08 ENST00000321797.12
LIM domain 7
chr7_+_129188622 0.08 ENST00000249373.8
smoothened, frizzled class receptor
chr1_+_109548567 0.08 ENST00000369851.7
G protein subunit alpha i3
chr4_+_112231748 0.08 ENST00000274000.10
ENST00000309703.10
adaptor related protein complex 1 associated regulatory protein
chr7_-_106285898 0.08 ENST00000424768.2
ENST00000681255.1
nicotinamide phosphoribosyltransferase
chr20_-_13990609 0.08 ENST00000284951.10
ENST00000378072.5
SEL1L2 adaptor subunit of ERAD E3 ligase
chr20_-_46089905 0.07 ENST00000372291.3
ENST00000290231.11
nuclear receptor coactivator 5
chr12_-_48570046 0.07 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr2_-_17800195 0.07 ENST00000402989.5
ENST00000428868.1
structural maintenance of chromosomes 6
chr13_+_75636311 0.07 ENST00000377499.9
ENST00000377534.8
LIM domain 7
chr5_-_149551381 0.07 ENST00000670598.1
ENST00000657001.1
ENST00000515768.6
ENST00000261798.10
ENST00000377843.8
casein kinase 1 alpha 1
chr2_+_26848424 0.07 ENST00000431402.5
ENST00000614712.4
ENST00000434719.1
dihydropyrimidinase like 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 0.7 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.4 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.6 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.6 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.5 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.2 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.2 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.5 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 1.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.0 1.2 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:1903634 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.0 0.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.4 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.0 GO:0015744 succinate transport(GO:0015744) sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) succinate transmembrane transport(GO:0071422)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 0.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.3 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 2.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines