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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TCF7L2

Z-value: 0.64

Motif logo

Transcription factors associated with TCF7L2

Gene Symbol Gene ID Gene Info
ENSG00000148737.17 TCF7L2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L2hg38_v1_chr10_+_112950757_112950916-0.321.2e-01Click!

Activity profile of TCF7L2 motif

Sorted Z-values of TCF7L2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_99646025 3.64 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr13_-_71867192 3.05 ENST00000611519.4
ENST00000620444.4
ENST00000613252.5
dachshund family transcription factor 1
chr1_+_60865259 2.13 ENST00000371191.5
nuclear factor I A
chr13_+_31945826 2.07 ENST00000647500.1
FRY microtubule binding protein
chr7_-_27174253 1.88 ENST00000613671.1
homeobox A10
chr7_-_27174274 1.88 ENST00000283921.5
homeobox A10
chr7_-_27180230 1.59 ENST00000396344.4
homeobox A10
chrX_-_63785510 1.54 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr17_-_69141878 1.50 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr13_-_71866769 1.46 ENST00000619232.1
dachshund family transcription factor 1
chr11_+_7576408 1.45 ENST00000533792.5
PPFIA binding protein 2
chr3_-_15797930 1.43 ENST00000683139.1
ankyrin repeat domain 28
chr10_+_123135938 1.39 ENST00000357878.7
H6 family homeobox 3
chr2_+_69013170 1.16 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr7_+_94394886 1.05 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr1_+_162381703 0.97 ENST00000458626.4
chromosome 1 open reading frame 226
chr8_+_30095400 0.91 ENST00000321250.13
ENST00000518001.1
ENST00000520682.5
ENST00000442880.6
ENST00000523116.5
leptin receptor overlapping transcript like 1
chr4_+_30720348 0.88 ENST00000361762.3
protocadherin 7
chr8_+_30095649 0.81 ENST00000518192.5
leptin receptor overlapping transcript like 1
chrX_-_10620534 0.74 ENST00000317552.9
midline 1
chrX_-_10620419 0.74 ENST00000380782.6
midline 1
chr10_+_52314272 0.73 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr18_+_6729698 0.72 ENST00000383472.9
Rho GTPase activating protein 28
chr1_-_110390989 0.72 ENST00000369779.9
ENST00000472422.6
solute carrier family 16 member 4
chr4_-_74099187 0.70 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr1_-_110391041 0.69 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr1_-_162023826 0.64 ENST00000294794.8
olfactomedin like 2B
chr9_+_125748175 0.63 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr22_-_32464440 0.63 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr10_-_14572123 0.61 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
family with sequence similarity 107 member B
chr13_+_75760362 0.61 ENST00000534657.5
LIM domain 7
chr16_+_29808125 0.60 ENST00000568282.1
MYC associated zinc finger protein
chr5_+_175861628 0.60 ENST00000509837.5
complexin 2
chr20_-_17531366 0.60 ENST00000377873.8
beaded filament structural protein 1
chr7_+_27242796 0.59 ENST00000496902.7
even-skipped homeobox 1
chr16_+_29808051 0.58 ENST00000568544.5
ENST00000569978.1
MYC associated zinc finger protein
chr7_-_148884266 0.58 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr1_+_77918128 0.56 ENST00000342754.5
nexilin F-actin binding protein
chr5_-_149551381 0.55 ENST00000670598.1
ENST00000657001.1
ENST00000515768.6
ENST00000261798.10
ENST00000377843.8
casein kinase 1 alpha 1
chr5_-_135954962 0.55 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr2_+_200440649 0.54 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr4_+_169660062 0.53 ENST00000507875.5
ENST00000613795.4
chloride voltage-gated channel 3
chr12_+_8914525 0.53 ENST00000543824.5
polyhomeotic homolog 1
chr22_+_19962537 0.52 ENST00000449653.5
catechol-O-methyltransferase
chr7_-_148884159 0.51 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr11_-_40294089 0.50 ENST00000278198.2
leucine rich repeat containing 4C
chr1_-_109393197 0.50 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr18_+_48539112 0.49 ENST00000382998.8
cap binding complex dependent translation initiation factor
chr8_-_17002327 0.49 ENST00000180166.6
fibroblast growth factor 20
chr5_-_149551168 0.49 ENST00000515748.2
ENST00000606719.6
casein kinase 1 alpha 1
chrX_+_153494970 0.48 ENST00000331595.9
ENST00000431891.1
biglycan
chr2_-_55419821 0.46 ENST00000644630.1
ENST00000471947.2
ENST00000436346.7
ENST00000642200.1
ENST00000413716.7
ENST00000263630.13
ENST00000645072.1
coiled-coil domain containing 88A
chr7_+_80646305 0.46 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr18_+_48539017 0.46 ENST00000256413.8
cap binding complex dependent translation initiation factor
chr12_+_8914464 0.45 ENST00000544916.6
polyhomeotic homolog 1
chr12_-_12338674 0.45 ENST00000545735.1
MANSC domain containing 1
chr7_-_80512041 0.45 ENST00000398291.4
G protein subunit alpha transducin 3
chr18_-_55321640 0.43 ENST00000637169.2
transcription factor 4
chr10_-_86957582 0.43 ENST00000372027.10
multimerin 2
chr2_-_55419565 0.43 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
coiled-coil domain containing 88A
chr11_-_95232514 0.42 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr2_+_172821575 0.42 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr1_-_93614091 0.42 ENST00000370247.7
BCAR3 adaptor protein, NSP family member
chr2_+_172860038 0.42 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr4_-_145938775 0.41 ENST00000508784.6
zinc finger protein 827
chr11_+_45922640 0.41 ENST00000401752.6
ENST00000325468.9
LARGE xylosyl- and glucuronyltransferase 2
chr6_-_112254485 0.40 ENST00000521398.5
ENST00000424408.6
ENST00000243219.7
laminin subunit alpha 4
chrX_-_32155462 0.40 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr13_+_75760659 0.39 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr14_-_80959484 0.39 ENST00000555529.5
ENST00000556042.5
ENST00000556981.5
centrosomal protein 128
chr1_+_147541491 0.38 ENST00000683836.1
ENST00000234739.8
BCL9 transcription coactivator
chr13_+_75760431 0.38 ENST00000321797.12
LIM domain 7
chr6_-_112254555 0.37 ENST00000230538.12
ENST00000389463.9
ENST00000368638.5
ENST00000431543.6
ENST00000453937.2
laminin subunit alpha 4
chr12_-_52385649 0.37 ENST00000257951.3
keratin 84
chr12_-_48570046 0.36 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr7_+_100015572 0.36 ENST00000535170.5
zinc finger with KRAB and SCAN domains 1
chr11_-_62707581 0.35 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2 lipid droplet biogenesis associated, seipin
chr18_+_32190015 0.34 ENST00000581447.1
meprin A subunit beta
chr15_+_57219411 0.34 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
transcription factor 12
chr6_-_112254647 0.34 ENST00000455073.1
ENST00000522006.5
ENST00000519932.5
laminin subunit alpha 4
chrX_+_54809060 0.34 ENST00000396224.1
MAGE family member D2
chr17_+_77451244 0.34 ENST00000591088.5
septin 9
chr18_+_32190033 0.33 ENST00000269202.11
meprin A subunit beta
chr6_-_32178080 0.32 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr17_-_65561640 0.32 ENST00000618960.4
ENST00000307078.10
axin 2
chr3_+_183635605 0.31 ENST00000493074.1
ENST00000437402.5
ENST00000454495.6
ENST00000473045.5
ENST00000468101.5
ENST00000427201.2
ENST00000482138.1
ENST00000454652.6
ENST00000242810.11
kelch like family member 24
chr7_+_27242700 0.31 ENST00000222761.7
even-skipped homeobox 1
chr1_-_39901996 0.30 ENST00000397332.2
MYCL proto-oncogene, bHLH transcription factor
chr2_-_69961624 0.30 ENST00000320256.6
aspartic peptidase retroviral like 1
chr5_+_58583068 0.29 ENST00000282878.6
RAB3C, member RAS oncogene family
chr1_+_222928415 0.29 ENST00000284476.7
dispatched RND transporter family member 1
chr19_+_49581304 0.28 ENST00000246794.10
proline rich and Gla domain 2
chr15_-_89751292 0.28 ENST00000300057.4
mesoderm posterior bHLH transcription factor 1
chr5_+_161850597 0.27 ENST00000634335.1
ENST00000635880.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr14_+_74763308 0.27 ENST00000325680.12
ENST00000552421.5
YLP motif containing 1
chr11_-_62707413 0.27 ENST00000360796.10
ENST00000449636.6
BSCL2 lipid droplet biogenesis associated, seipin
chr17_+_81712236 0.27 ENST00000545862.5
ENST00000350690.10
ENST00000331531.9
solute carrier family 25 member 10
chr18_-_55321986 0.26 ENST00000570287.6
transcription factor 4
chr2_+_48568981 0.26 ENST00000394754.5
STON1-GTF2A1L readthrough
chr11_-_6006946 0.25 ENST00000641156.1
ENST00000641835.1
olfactory receptor family 56 subfamily A member 4
chr12_+_70366277 0.25 ENST00000258111.5
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr7_+_100015588 0.25 ENST00000324306.11
ENST00000426572.5
zinc finger with KRAB and SCAN domains 1
chr14_+_22766522 0.25 ENST00000285848.9
ENST00000612549.6
ENST00000431881.6
ENST00000412791.5
ENST00000358043.5
OXA1L mitochondrial inner membrane protein
chrX_-_100928903 0.24 ENST00000372956.3
XK related X-linked
chrX_+_47078380 0.24 ENST00000352078.8
regucalcin
chr3_-_134374439 0.24 ENST00000513145.1
ENST00000249883.10
ENST00000422605.6
angiomotin like 2
chr2_+_233712905 0.24 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr10_+_99782628 0.24 ENST00000648689.1
ENST00000647814.1
ATP binding cassette subfamily C member 2
chr6_+_155216637 0.23 ENST00000275246.11
TIAM Rac1 associated GEF 2
chrX_+_47078434 0.23 ENST00000397180.6
regucalcin
chr2_-_55917699 0.23 ENST00000634374.1
EGF containing fibulin extracellular matrix protein 1
chr4_-_68349750 0.22 ENST00000579690.5
YTH domain containing 1
chr19_+_1266653 0.22 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr1_+_16004228 0.22 ENST00000329454.2
steroid receptor associated and regulated protein
chr16_+_53208438 0.22 ENST00000565442.1
chromodomain helicase DNA binding protein 9
chr9_-_4741176 0.22 ENST00000381809.8
adenylate kinase 3
chr7_+_80646436 0.21 ENST00000419819.2
CD36 molecule
chr9_-_15510289 0.21 ENST00000397519.6
PC4 and SFRS1 interacting protein 1
chr17_+_70104848 0.21 ENST00000392670.5
potassium inwardly rectifying channel subfamily J member 16
chr17_-_40100569 0.21 ENST00000246672.4
nuclear receptor subfamily 1 group D member 1
chr10_-_102419934 0.20 ENST00000406432.5
pleckstrin and Sec7 domain containing
chr6_-_28252246 0.19 ENST00000377294.3
zinc finger with KRAB and SCAN domains 4
chr6_-_166167832 0.19 ENST00000366876.7
T-box transcription factor T
chrX_+_41447322 0.19 ENST00000378220.2
ENST00000342595.2
nyctalopin
chr14_+_20768393 0.19 ENST00000326783.4
epididymal protein 3B
chr5_+_55160161 0.18 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr2_+_69013379 0.18 ENST00000409349.7
ANTXR cell adhesion molecule 1
chrX_+_47078330 0.18 ENST00000457380.5
regucalcin
chr4_+_77157189 0.18 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr11_+_111878926 0.18 ENST00000528125.5
chromosome 11 open reading frame 1
chr2_+_69013282 0.17 ENST00000409829.7
ANTXR cell adhesion molecule 1
chr1_-_53838276 0.16 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr5_+_102865805 0.16 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr10_-_102419693 0.16 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr1_+_180230257 0.16 ENST00000263726.4
LIM homeobox 4
chr7_+_114416286 0.16 ENST00000635534.1
forkhead box P2
chr2_+_203936755 0.15 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr3_-_42410558 0.15 ENST00000441172.1
ENST00000287748.8
lysozyme like 4
chr5_-_157575767 0.15 ENST00000257527.9
ADAM metallopeptidase domain 19
chr13_-_35855627 0.15 ENST00000379893.5
doublecortin like kinase 1
chr14_-_63318933 0.15 ENST00000621500.2
glycoprotein hormone subunit beta 5
chr16_+_19211157 0.14 ENST00000568433.1
synaptotagmin 17
chr22_-_33572227 0.13 ENST00000674780.1
LARGE xylosyl- and glucuronyltransferase 1
chrX_+_106920393 0.13 ENST00000336803.2
claudin 2
chr16_-_73048104 0.13 ENST00000268489.10
zinc finger homeobox 3
chr16_+_72054477 0.12 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr7_-_151814668 0.12 ENST00000651764.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr1_+_154272589 0.12 ENST00000457918.6
ENST00000483970.6
ENST00000328703.12
ENST00000435087.1
ENST00000532105.1
HCLS1 associated protein X-1
chr2_+_201071984 0.12 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr18_+_10454584 0.11 ENST00000355285.10
APC down-regulated 1
chr10_-_103917657 0.11 ENST00000369764.1
STN1 subunit of CST complex
chr14_+_21797272 0.10 ENST00000390430.2
T cell receptor alpha variable 8-1
chr17_+_36492202 0.10 ENST00000612494.4
ENST00000622013.1
zinc finger HIT-type containing 3
chr14_+_32329341 0.09 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr10_-_102432565 0.09 ENST00000369937.5
CUE domain containing 2
chrX_+_101390976 0.09 ENST00000392994.7
ribosomal protein L36a
chr1_-_32336224 0.09 ENST00000329421.8
MARCKS like 1
chr6_-_34248989 0.09 ENST00000481533.5
ENST00000468145.1
ENST00000476320.6
ENST00000394990.8
small integral membrane protein 29
chr17_+_44004604 0.08 ENST00000293404.8
ENST00000589767.1
N-acetylglutamate synthase
chrX_+_101391202 0.08 ENST00000471855.1
ribosomal protein L36a
chr4_+_112860912 0.08 ENST00000671951.1
ankyrin 2
chr11_-_41459592 0.08 ENST00000528697.6
ENST00000530763.5
leucine rich repeat containing 4C
chr7_-_151814636 0.08 ENST00000652047.1
ENST00000650858.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr3_+_141368497 0.08 ENST00000321464.7
zinc finger and BTB domain containing 38
chrX_+_101391000 0.08 ENST00000553110.8
ENST00000409338.5
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr17_-_39864304 0.07 ENST00000346872.8
IKAROS family zinc finger 3
chr7_+_150379316 0.07 ENST00000483664.5
ENST00000329630.10
novel transcript
zinc finger protein 775
chr4_+_112860981 0.07 ENST00000671704.1
ankyrin 2
chr7_+_69598465 0.07 ENST00000342771.10
activator of transcription and developmental regulator AUTS2
chr19_-_51082883 0.07 ENST00000650543.2
kallikrein related peptidase 14
chr2_-_71130214 0.07 ENST00000494660.6
ENST00000244217.6
ENST00000486135.1
methylmalonyl-CoA epimerase
chr3_+_174859315 0.07 ENST00000454872.6
N-acetylated alpha-linked acidic dipeptidase like 2
chr19_-_58519751 0.07 ENST00000600990.1
ENST00000594051.6
zinc finger and BTB domain containing 45
chr4_+_112861053 0.06 ENST00000672221.1
ankyrin 2
chr6_+_35737028 0.06 ENST00000373869.7
ENST00000373866.4
armadillo repeat containing 12
chr7_-_149028452 0.06 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr9_+_123033660 0.05 ENST00000616002.3
G protein-coupled receptor 21
chr17_-_41489907 0.05 ENST00000328119.11
keratin 36
chrX_+_47145200 0.05 ENST00000377604.8
RNA binding motif protein 10
chr19_-_58519554 0.05 ENST00000354590.7
ENST00000596739.1
zinc finger and BTB domain containing 45
chr6_+_35737078 0.05 ENST00000288065.6
armadillo repeat containing 12
chr13_-_35855758 0.05 ENST00000615680.4
doublecortin like kinase 1
chr15_-_93089192 0.05 ENST00000329082.11
repulsive guidance molecule BMP co-receptor a
chr17_-_49230728 0.04 ENST00000503902.1
ENST00000512250.1
ENST00000413580.5
ENST00000511066.5
phosphoethanolamine/phosphocholine phosphatase 1
chr14_+_92652468 0.04 ENST00000556418.1
Ras and Rab interactor 3
chr6_-_34249102 0.04 ENST00000636500.1
small integral membrane protein 29
chr7_-_149028651 0.04 ENST00000286091.9
protein disulfide isomerase family A member 4
chr20_-_57265738 0.04 ENST00000433911.1
bone morphogenetic protein 7
chr14_+_74348440 0.04 ENST00000256362.5
vertebrae development associated
chr20_+_59300402 0.04 ENST00000311585.11
ENST00000371028.6
endothelin 3
chrX_+_101390824 0.03 ENST00000427805.6
ENST00000614077.4
ribosomal protein L36a
chr8_-_94208548 0.03 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
cadherin 17
chr7_+_111091006 0.03 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr17_-_42018488 0.03 ENST00000589773.5
ENST00000674214.1
DnaJ heat shock protein family (Hsp40) member C7
chrX_-_40097403 0.03 ENST00000397354.7
BCL6 corepressor
chr19_-_39433703 0.03 ENST00000602153.5
ribosomal protein S16
chr4_-_108762964 0.03 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ethanolamine-phosphate phospho-lyase
chr7_+_111091119 0.02 ENST00000308478.10
leucine rich repeat neuronal 3
chr22_+_40951364 0.02 ENST00000216225.9
ring-box 1
chrX_-_123733023 0.02 ENST00000245838.13
ENST00000355725.8
THO complex 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.5 4.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 1.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.3 0.9 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 1.3 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.3 1.0 GO:0042662 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of mesodermal cell fate specification(GO:0042662)
0.2 1.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 0.6 GO:1903631 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.1 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 5.3 GO:0060065 uterus development(GO:0060065)
0.1 1.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.4 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.6 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.5 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 0.5 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.2 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.1 0.7 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 2.1 GO:0072189 ureter development(GO:0072189)
0.1 1.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.2 GO:0060086 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.3 GO:0015744 succinate transport(GO:0015744) sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) succinate transmembrane transport(GO:0071422)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.2 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.4 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 1.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 1.0 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.0 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 1.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0046051 UTP metabolic process(GO:0046051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.1 GO:0045120 pronucleus(GO:0045120)
0.1 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.1 GO:0005605 basal lamina(GO:0005605)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005816 spindle pole body(GO:0005816)
0.0 4.5 GO:0043197 dendritic spine(GO:0043197)
0.0 9.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.5 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 0.6 GO:0004341 gluconolactonase activity(GO:0004341)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 1.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 3.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity(GO:0004952)
0.0 1.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation