Project
Inflammatory response time course, HUVEC (Wada, 2009)
Navigation
Downloads
Results for TEAD3_TEAD1
Z-value: 2.30
Motif logo
Transcription factors associated with TEAD3_TEAD1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TEAD1 | hg38_v1_chr11_+_12674397_12674442 | 0.84 | 1.5e-07 | Click! |
| TEAD3 | hg38_v1_chr6_-_35497042_35497117 | 0.08 | 7.1e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TEAD3_TEAD1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 29.0 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.4 | 21.9 | GO:0000305 | response to oxygen radical(GO:0000305) |
| 1.9 | 20.6 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.6 | 16.0 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 15.5 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 5.1 | 15.3 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 1.0 | 15.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 14.4 | GO:0007286 | spermatid development(GO:0007286) |
| 3.2 | 12.8 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 0.3 | 12.1 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 29.4 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 23.4 | GO:0030018 | Z disc(GO:0030018) |
| 0.8 | 20.6 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 19.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 2.5 | 15.3 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 15.0 | GO:0000922 | spindle pole(GO:0000922) |
| 0.4 | 14.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.4 | 11.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.2 | 11.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 8.3 | GO:0000139 | Golgi membrane(GO:0000139) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 48.3 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.9 | 28.1 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 1.4 | 21.9 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.0 | 20.5 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.6 | 15.3 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 14.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.2 | 11.8 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 9.9 | GO:0003779 | actin binding(GO:0003779) |
| 1.5 | 9.0 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 1.4 | 8.3 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 40.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.2 | 25.9 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 10.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 10.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 7.3 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 6.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 6.5 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 6.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 6.0 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 5.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 19.6 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.7 | 14.8 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.2 | 11.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 9.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 8.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.2 | 8.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 7.2 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 6.8 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 6.2 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.2 | 6.1 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |