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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TEAD4

Z-value: 0.66

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Transcription factors associated with TEAD4

Gene Symbol Gene ID Gene Info
TEAD4
ENSG00000197905.10 TEAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD4hg38_v1_chr12_+_2959296_2959431,
hg38_v1_chr12_+_2959870_2959953		0.019.5e-01Click!

Activity profile of TEAD4 motif

Sorted Z-values of TEAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_227813834 2.55 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr4_-_158159657 1.24 ENST00000590648.5
GASK1B
golgi associated kinase 1B
chr12_-_9760893 1.22 ENST00000228434.7
ENST00000536709.1
CD69
CD69 molecule
chr4_+_94489030 0.93 ENST00000510099.5
PDLIM5
PDZ and LIM domain 5
chr17_+_34255274 0.81 ENST00000580907.5
ENST00000225831.4
CCL2
C-C motif chemokine ligand 2
chr2_-_136118142 0.79 ENST00000241393.4
CXCR4
C-X-C motif chemokine receptor 4
chr2_-_234497035 0.77 ENST00000390645.2
ENST00000339728.6
ARL4C
ADP ribosylation factor like GTPase 4C
chr14_+_75605462 0.74 ENST00000539311.5
FLVCR2
FLVCR heme transporter 2
chr2_+_200440649 0.73 ENST00000366118.2
SPATS2L
spermatogenesis associated serine rich 2 like
chr7_-_22194709 0.70 ENST00000458533.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr7_-_36985060 0.69 ENST00000396040.6
ELMO1
engulfment and cell motility 1
chr3_+_101827982 0.69 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr11_-_128587551 0.68 ENST00000392668.8
ETS1
ETS proto-oncogene 1, transcription factor
chr4_+_41612702 0.67 ENST00000509277.5
LIMCH1
LIM and calponin homology domains 1
chr4_+_41612892 0.60 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr3_-_185821092 0.59 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr2_+_151357583 0.55 ENST00000243347.5
TNFAIP6
TNF alpha induced protein 6
chr5_-_32312913 0.55 ENST00000280285.9
ENST00000382142.8
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr10_-_49762276 0.50 ENST00000374103.9
OGDHL
oxoglutarate dehydrogenase L
chr10_-_49762335 0.48 ENST00000419399.4
ENST00000432695.2
OGDHL
oxoglutarate dehydrogenase L
chr11_-_118925916 0.47 ENST00000683865.1
BCL9L
BCL9 like
chr12_-_24903014 0.46 ENST00000539282.5
BCAT1
branched chain amino acid transaminase 1
chr6_-_159726871 0.45 ENST00000535561.5
SOD2
superoxide dismutase 2
chr7_+_77538027 0.44 ENST00000433369.6
ENST00000415482.6
PTPN12
protein tyrosine phosphatase non-receptor type 12
chr9_+_72577369 0.43 ENST00000651183.1
TMC1
transmembrane channel like 1
chr1_+_65992389 0.43 ENST00000423207.6
PDE4B
phosphodiesterase 4B
chr10_+_84452208 0.41 ENST00000480006.1
CCSER2
coiled-coil serine rich protein 2
chr8_+_22367526 0.40 ENST00000289952.9
ENST00000524285.1
SLC39A14
solute carrier family 39 member 14
chr9_+_128566741 0.39 ENST00000630866.1
SPTAN1
spectrin alpha, non-erythrocytic 1
chr15_-_68820861 0.38 ENST00000560303.1
ENST00000465139.6
ANP32A
acidic nuclear phosphoprotein 32 family member A
chr3_+_112086335 0.36 ENST00000431717.6
ENST00000480282.5
C3orf52
chromosome 3 open reading frame 52
chr4_-_88231322 0.36 ENST00000515655.5
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group)
chr14_+_30577752 0.35 ENST00000547532.5
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr8_+_106447918 0.35 ENST00000442977.6
OXR1
oxidation resistance 1
chr7_-_82443715 0.35 ENST00000356253.9
ENST00000423588.1
CACNA2D1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr9_+_113594118 0.34 ENST00000620489.1
RGS3
regulator of G protein signaling 3
chrX_+_21374288 0.34 ENST00000642359.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr2_-_187554473 0.34 ENST00000453013.5
ENST00000417013.5
TFPI
tissue factor pathway inhibitor
chr9_-_127847117 0.32 ENST00000480266.5
ENG
endoglin
chr4_+_185395979 0.30 ENST00000507753.1
ANKRD37
ankyrin repeat domain 37
chr11_+_102347312 0.29 ENST00000621637.1
ENST00000613397.4
BIRC2
baculoviral IAP repeat containing 2
chr17_-_18682262 0.29 ENST00000454745.2
ENST00000395675.7
FOXO3B
forkhead box O3B
chr6_-_117573571 0.29 ENST00000467125.1
ENSG00000282218.1
novel protein, GOPC-ROS1 readthrough
chr6_-_41071825 0.29 ENST00000468811.5
OARD1
O-acyl-ADP-ribose deacylase 1
chr17_+_42458844 0.29 ENST00000393829.6
ENST00000537728.5
ENST00000343619.9
ENST00000264649.10
ENST00000585525.5
ENST00000544137.5
ENST00000589727.5
ENST00000587824.5
ATP6V0A1
ATPase H+ transporting V0 subunit a1
chr5_+_139308095 0.29 ENST00000515833.2
MATR3
matrin 3
chr1_+_154257071 0.28 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2 like
chr8_-_23854796 0.28 ENST00000290271.7
STC1
stanniocalcin 1
chr5_-_95081482 0.27 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr22_-_50085414 0.27 ENST00000311597.10
MLC1
modulator of VRAC current 1
chr2_+_237858874 0.26 ENST00000404910.6
RAMP1
receptor activity modifying protein 1
chr2_+_108288869 0.26 ENST00000251481.11
ENST00000438339.5
ENST00000409880.5
ENST00000437390.6
SULT1C2
sulfotransferase family 1C member 2
chr10_-_73651013 0.26 ENST00000372873.8
SYNPO2L
synaptopodin 2 like
chr22_-_50085331 0.26 ENST00000395876.6
MLC1
modulator of VRAC current 1
chr1_-_154956086 0.26 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBXIP1
PBX homeobox interacting protein 1
chr11_-_118264282 0.26 ENST00000278937.7
MPZL2
myelin protein zero like 2
chr3_-_18424533 0.25 ENST00000417717.6
SATB1
SATB homeobox 1
chr3_-_71132099 0.24 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
FOXP1
forkhead box P1
chr6_-_42722590 0.24 ENST00000230381.7
PRPH2
peripherin 2
chr17_-_68955332 0.24 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ABCA8
ATP binding cassette subfamily A member 8
chr3_-_197260369 0.24 ENST00000658155.1
ENST00000453607.5
DLG1
discs large MAGUK scaffold protein 1
chr1_+_241532370 0.23 ENST00000366559.9
ENST00000366557.8
KMO
kynurenine 3-monooxygenase
chrX_+_21374608 0.23 ENST00000644295.1
ENST00000645074.1
ENST00000645791.1
ENST00000643220.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr4_-_185810894 0.22 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
SORBS2
sorbin and SH3 domain containing 2
chr6_-_52840843 0.22 ENST00000370989.6
GSTA5
glutathione S-transferase alpha 5
chr6_-_46325641 0.21 ENST00000330430.10
ENST00000405162.2
RCAN2
regulator of calcineurin 2
chr1_+_89633086 0.21 ENST00000370454.9
LRRC8C
leucine rich repeat containing 8 VRAC subunit C
chr17_-_40937641 0.21 ENST00000209718.8
KRT23
keratin 23
chr2_-_231125032 0.21 ENST00000258400.4
HTR2B
5-hydroxytryptamine receptor 2B
chr4_+_95091462 0.21 ENST00000264568.8
BMPR1B
bone morphogenetic protein receptor type 1B
chr20_+_44531817 0.20 ENST00000372889.5
ENST00000372887.5
PKIG
cAMP-dependent protein kinase inhibitor gamma
chr8_+_66493514 0.20 ENST00000521495.5
VXN
vexin
chr3_-_71130963 0.20 ENST00000649695.2
FOXP1
forkhead box P1
chr4_-_109801978 0.19 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
CFI
ENSG00000285330.1
complement factor I
novel protein
chr13_-_37105664 0.19 ENST00000379800.4
CSNK1A1L
casein kinase 1 alpha 1 like
chr6_-_132659178 0.19 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr18_+_6834473 0.19 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
ARHGAP28
Rho GTPase activating protein 28
chr7_+_77538059 0.19 ENST00000435495.6
PTPN12
protein tyrosine phosphatase non-receptor type 12
chr4_-_144140712 0.19 ENST00000641688.3
GYPA
glycophorin A (MNS blood group)
chr6_+_112236806 0.19 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4-AS1
ENSG00000281613.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chr15_-_70702273 0.18 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_+_18262730 0.18 ENST00000675017.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr4_-_144140725 0.18 ENST00000360771.8
GYPA
glycophorin A (MNS blood group)
chr2_-_196068812 0.18 ENST00000410072.5
ENST00000312428.11
DNAH7
dynein axonemal heavy chain 7
chr3_-_71130557 0.18 ENST00000497355.7
FOXP1
forkhead box P1
chr12_-_57826295 0.18 ENST00000549039.5
CTDSP2
CTD small phosphatase 2
chr2_+_190927649 0.17 ENST00000409428.5
ENST00000409215.5
GLS
glutaminase
chr15_+_59438149 0.17 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
FAM81A
family with sequence similarity 81 member A
chr7_+_54542393 0.17 ENST00000404951.5
VSTM2A
V-set and transmembrane domain containing 2A
chr6_+_159726998 0.17 ENST00000614346.4
WTAP
WT1 associated protein
chr12_-_91178520 0.17 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
DCN
decorin
chr17_+_81395469 0.17 ENST00000584436.7
BAHCC1
BAH domain and coiled-coil containing 1
chr16_-_20669855 0.16 ENST00000524149.5
ACSM1
acyl-CoA synthetase medium chain family member 1
chr3_-_71130892 0.16 ENST00000491238.7
ENST00000674446.1
FOXP1
forkhead box P1
chr14_+_21797272 0.16 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr17_+_81395449 0.16 ENST00000675386.2
BAHCC1
BAH domain and coiled-coil containing 1
chr18_+_58195390 0.16 ENST00000456173.6
ENST00000676226.1
ENST00000675865.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr1_+_160796157 0.16 ENST00000263285.11
ENST00000368039.2
LY9
lymphocyte antigen 9
chr18_-_3219961 0.15 ENST00000356443.9
MYOM1
myomesin 1
chrX_+_37780049 0.15 ENST00000378588.5
CYBB
cytochrome b-245 beta chain
chr8_-_69833338 0.15 ENST00000524945.5
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr7_+_54542362 0.15 ENST00000402613.4
VSTM2A
V-set and transmembrane domain containing 2A
chr7_+_54542300 0.15 ENST00000302287.7
ENST00000407838.7
VSTM2A
V-set and transmembrane domain containing 2A
chr17_-_40937445 0.14 ENST00000436344.7
ENST00000485751.1
KRT23
keratin 23
chr6_-_166168700 0.14 ENST00000366871.7
TBXT
T-box transcription factor T
chr16_-_29862890 0.14 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr18_-_55422306 0.14 ENST00000566777.5
ENST00000626584.2
TCF4
transcription factor 4
chr3_+_14675128 0.14 ENST00000435614.5
ENST00000253697.8
ENST00000412910.1
C3orf20
chromosome 3 open reading frame 20
chrX_+_21374434 0.14 ENST00000279451.9
ENST00000645245.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr6_-_166168612 0.14 ENST00000296946.6
TBXT
T-box transcription factor T
chr2_-_157327699 0.13 ENST00000397283.6
ERMN
ermin
chr1_-_225999312 0.13 ENST00000272091.8
SDE2
SDE2 telomere maintenance homolog
chr2_-_60553558 0.13 ENST00000642439.1
ENST00000356842.9
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr2_-_160200310 0.13 ENST00000620391.4
ITGB6
integrin subunit beta 6
chr15_+_99566066 0.12 ENST00000557942.5
MEF2A
myocyte enhancer factor 2A
chr20_+_35226676 0.12 ENST00000246186.8
MMP24
matrix metallopeptidase 24
chr7_-_47948448 0.12 ENST00000289672.7
PKD1L1
polycystin 1 like 1, transient receptor potential channel interacting
chr3_-_112638097 0.12 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr12_-_122526929 0.12 ENST00000331738.12
ENST00000528279.1
ENST00000344591.8
ENST00000526560.6
RSRC2
arginine and serine rich coiled-coil 2
chr11_-_55936400 0.12 ENST00000301532.3
OR5I1
olfactory receptor family 5 subfamily I member 1
chr12_-_21604840 0.12 ENST00000261195.3
GYS2
glycogen synthase 2
chr3_-_71360753 0.12 ENST00000648783.1
FOXP1
forkhead box P1
chr20_+_5750437 0.12 ENST00000445603.1
ENST00000442185.1
SHLD1
shieldin complex subunit 1
chr5_+_173889337 0.12 ENST00000520867.5
ENST00000334035.9
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr4_-_39032343 0.12 ENST00000381938.4
TMEM156
transmembrane protein 156
chr9_+_122510802 0.12 ENST00000335302.5
OR1J2
olfactory receptor family 1 subfamily J member 2
chr19_+_35139440 0.12 ENST00000455515.6
FXYD1
FXYD domain containing ion transport regulator 1
chr12_+_32107296 0.12 ENST00000551086.1
BICD1
BICD cargo adaptor 1
chr15_+_99565950 0.12 ENST00000557785.5
ENST00000558049.5
ENST00000449277.6
MEF2A
myocyte enhancer factor 2A
chr15_+_99565921 0.12 ENST00000558812.5
ENST00000338042.10
MEF2A
myocyte enhancer factor 2A
chr21_+_46286623 0.12 ENST00000397691.1
YBEY
ybeY metalloendoribonuclease
chr3_+_138348823 0.12 ENST00000475711.5
ENST00000464896.5
MRAS
muscle RAS oncogene homolog
chr6_+_108848387 0.11 ENST00000368972.7
ENST00000392644.9
ARMC2
armadillo repeat containing 2
chr19_+_35139724 0.11 ENST00000588715.5
ENST00000588607.5
FXYD1
FXYD domain containing ion transport regulator 1
chr2_-_187554351 0.11 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
TFPI
tissue factor pathway inhibitor
chr1_-_11848345 0.11 ENST00000376476.1
NPPA
natriuretic peptide A
chr2_-_160200251 0.11 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
ITGB6
integrin subunit beta 6
chr1_+_241532121 0.10 ENST00000366558.7
KMO
kynurenine 3-monooxygenase
chr12_-_54258275 0.10 ENST00000552562.1
CBX5
chromobox 5
chr18_+_58341038 0.10 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr6_+_31655888 0.10 ENST00000375916.4
APOM
apolipoprotein M
chr6_+_31670379 0.10 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 family member G5B
chr3_+_130560334 0.09 ENST00000358511.10
COL6A6
collagen type VI alpha 6 chain
chr7_-_108240049 0.09 ENST00000379022.8
NRCAM
neuronal cell adhesion molecule
chr5_-_180072086 0.09 ENST00000261947.4
RNF130
ring finger protein 130
chr11_+_62242232 0.09 ENST00000244926.4
SCGB1D2
secretoglobin family 1D member 2
chrX_-_54998530 0.09 ENST00000545676.5
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_+_15684284 0.09 ENST00000375799.8
ENST00000375793.2
PLEKHM2
pleckstrin homology and RUN domain containing M2
chr19_+_10013468 0.09 ENST00000591589.3
RDH8
retinol dehydrogenase 8
chr5_+_54455661 0.09 ENST00000302005.3
HSPB3
heat shock protein family B (small) member 3
chr21_-_46285608 0.09 ENST00000291688.6
MCM3AP
minichromosome maintenance complex component 3 associated protein
chr17_+_17782108 0.08 ENST00000395774.1
RAI1
retinoic acid induced 1
chr6_-_87702221 0.08 ENST00000257787.6
AKIRIN2
akirin 2
chrX_+_21374357 0.08 ENST00000643841.1
ENST00000379510.5
ENST00000425654.7
ENST00000644798.1
ENST00000543067.6
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chrX_+_80420466 0.08 ENST00000308293.5
TENT5D
terminal nucleotidyltransferase 5D
chr19_+_35138993 0.08 ENST00000612146.4
ENST00000589209.5
FXYD1
FXYD domain containing ion transport regulator 1
chr12_-_91146195 0.07 ENST00000548218.1
DCN
decorin
chr3_-_11643871 0.07 ENST00000430365.7
VGLL4
vestigial like family member 4
chr11_+_46936710 0.07 ENST00000378618.6
ENST00000278460.12
ENST00000395460.6
ENST00000378615.7
C11orf49
chromosome 11 open reading frame 49
chr11_+_6845683 0.07 ENST00000299454.5
OR10A5
olfactory receptor family 10 subfamily A member 5
chr3_-_177197248 0.07 ENST00000427349.5
ENST00000352800.10
TBL1XR1
TBL1X receptor 1
chr14_-_106803221 0.07 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr8_-_27258386 0.07 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
STMN4
stathmin 4
chr13_-_44437214 0.07 ENST00000622051.1
TSC22D1
TSC22 domain family member 1
chr10_+_15032193 0.06 ENST00000428897.5
ENST00000413672.5
OLAH
oleoyl-ACP hydrolase
chr9_+_68356899 0.06 ENST00000396392.5
PGM5
phosphoglucomutase 5
chr6_-_152168349 0.06 ENST00000539504.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr20_+_5750381 0.06 ENST00000378979.8
ENST00000303142.11
SHLD1
shieldin complex subunit 1
chr1_+_43269974 0.06 ENST00000439858.6
TMEM125
transmembrane protein 125
chr4_+_122239965 0.06 ENST00000446180.5
KIAA1109
KIAA1109
chr2_-_160200289 0.06 ENST00000409872.1
ITGB6
integrin subunit beta 6
chr6_-_152168291 0.06 ENST00000354674.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr20_-_13990609 0.06 ENST00000284951.10
ENST00000378072.5
SEL1L2
SEL1L2 adaptor subunit of ERAD E3 ligase
chr11_+_126327863 0.06 ENST00000648516.1
DCPS
decapping enzyme, scavenger
chr1_-_212847649 0.06 ENST00000332912.3
SPATA45
spermatogenesis associated 45
chr21_-_38498415 0.06 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chr1_+_43270007 0.05 ENST00000432792.6
TMEM125
transmembrane protein 125
chr3_-_15798184 0.05 ENST00000624145.3
ANKRD28
ankyrin repeat domain 28
chr12_-_39619782 0.05 ENST00000308666.4
ABCD2
ATP binding cassette subfamily D member 2
chr10_+_27532521 0.05 ENST00000683924.1
RAB18
RAB18, member RAS oncogene family
chr6_-_76072654 0.05 ENST00000369950.8
ENST00000611179.4
ENST00000369963.5
IMPG1
interphotoreceptor matrix proteoglycan 1
chr12_+_10307950 0.05 ENST00000543420.5
ENST00000543777.5
KLRD1
killer cell lectin like receptor D1
chr17_+_40062956 0.05 ENST00000450525.7
THRA
thyroid hormone receptor alpha
chr7_-_93148345 0.05 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
SAMD9L
sterile alpha motif domain containing 9 like
chr7_+_148133684 0.05 ENST00000628930.2
CNTNAP2
contactin associated protein 2
chr6_+_31670167 0.05 ENST00000375864.4
LY6G5B
lymphocyte antigen 6 family member G5B
chr10_+_62049211 0.05 ENST00000309334.5
ARID5B
AT-rich interaction domain 5B
chr1_+_43530847 0.05 ENST00000617451.4
ENST00000359947.9
ENST00000438120.5
PTPRF
protein tyrosine phosphatase receptor type F
chr9_+_68356603 0.05 ENST00000396396.6
PGM5
phosphoglucomutase 5
chr1_+_40738834 0.05 ENST00000525290.5
ENST00000530965.5
ENST00000416859.6
ENST00000308733.9
NFYC
nuclear transcription factor Y subunit gamma
chr9_-_71121596 0.05 ENST00000377110.9
ENST00000377111.8
ENST00000677713.2
TRPM3
transient receptor potential cation channel subfamily M member 3
chr12_+_80099535 0.05 ENST00000646859.1
ENST00000547103.7
OTOGL
otogelin like
chr10_+_24239181 0.05 ENST00000438429.5
KIAA1217
KIAA1217
chr8_-_27258414 0.05 ENST00000523048.5
STMN4
stathmin 4
chr3_+_186570663 0.04 ENST00000265028.8
DNAJB11
DnaJ heat shock protein family (Hsp40) member B11
chr11_-_84273188 0.04 ENST00000330014.11
ENST00000418306.6
ENST00000531015.5
DLG2
discs large MAGUK scaffold protein 2
chr11_+_9575496 0.04 ENST00000681684.1
WEE1
WEE1 G2 checkpoint kinase
chr8_+_42271289 0.04 ENST00000520810.6
ENST00000520835.7
IKBKB
inhibitor of nuclear factor kappa B kinase subunit beta
chr8_+_66493556 0.04 ENST00000305454.8
ENST00000522977.5
ENST00000480005.1
VXN
vexin
chr16_+_32995048 0.04 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 0.8 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.5 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.1 0.3 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.3 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.1 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.8 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.7 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.3 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0010513 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 1.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.3 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.0 GO:1903347 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 1.2 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072563 endothelial microparticle(GO:0072563)
0.1 1.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.3 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.3 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0005534 galactose binding(GO:0005534)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 3.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules