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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TFAP2B

Z-value: 1.15

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.13 TFAP2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg38_v1_chr6_+_50818857_508188770.395.1e-02Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_64206663 2.06 ENST00000544997.5
ENST00000345728.10
ENST00000279227.9
fermitin family member 3
chr3_-_158732442 2.06 ENST00000479756.1
ENST00000237696.10
retinoic acid receptor responder 1
chr22_-_35622521 1.69 ENST00000419229.1
ENST00000406324.5
myoglobin
chr11_+_69641146 1.67 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr9_+_114155526 1.58 ENST00000356083.8
collagen type XXVII alpha 1 chain
chr5_+_132073782 1.53 ENST00000296871.4
colony stimulating factor 2
chr1_+_65147830 1.53 ENST00000395334.6
adenylate kinase 4
chr1_+_65148169 1.45 ENST00000327299.8
adenylate kinase 4
chr11_-_7673485 1.36 ENST00000299498.11
cytochrome b5 reductase 2
chr11_-_7674206 1.35 ENST00000533558.5
ENST00000527542.5
cytochrome b5 reductase 2
chr21_+_42219123 1.33 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr1_+_65147514 1.32 ENST00000545314.5
adenylate kinase 4
chr21_+_42219111 1.31 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr6_-_159693262 1.29 ENST00000337404.8
superoxide dismutase 2
chr3_+_72888031 1.28 ENST00000389617.9
glucoside xylosyltransferase 2
chr16_-_67936808 1.24 ENST00000358514.9
proteasome 20S subunit beta 10
chr6_-_138107412 1.23 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr13_-_80341100 1.23 ENST00000377104.4
sprouty RTK signaling antagonist 2
chr17_-_74872961 1.22 ENST00000581530.5
ENST00000420580.6
ENST00000413947.6
ENST00000581219.1
ENST00000582944.5
ENST00000293195.10
ENST00000583917.5
ENST00000442102.6
ferredoxin reductase
chr5_-_151224069 1.19 ENST00000355417.7
coiled-coil domain containing 69
chr3_-_185499022 1.08 ENST00000421852.6
transmembrane protein 41A
chr19_+_42220283 1.07 ENST00000301215.8
ENST00000597945.1
zinc finger protein 526
chr4_+_1721470 1.05 ENST00000612220.5
ENST00000313288.9
transforming acidic coiled-coil containing protein 3
chr1_-_48776811 1.04 ENST00000371833.4
BEN domain containing 5
chr1_-_212699817 1.04 ENST00000243440.2
basic leucine zipper ATF-like transcription factor 3
chr15_+_58771280 1.02 ENST00000559228.6
ENST00000450403.3
MINDY lysine 48 deubiquitinase 2
chr1_+_169106681 0.97 ENST00000367815.9
ATPase Na+/K+ transporting subunit beta 1
chr3_-_108090971 0.94 ENST00000355354.13
ENST00000361309.6
CD47 molecule
chr5_+_98769273 0.94 ENST00000308234.11
repulsive guidance molecule BMP co-receptor b
chr8_+_38901218 0.93 ENST00000521746.5
ENST00000616927.4
pleckstrin homology domain containing A2
chr7_-_27130182 0.93 ENST00000511914.1
homeobox A4
chr4_-_184826030 0.92 ENST00000507295.5
ENST00000504900.5
ENST00000454703.6
acyl-CoA synthetase long chain family member 1
chr4_-_184825960 0.90 ENST00000281455.7
acyl-CoA synthetase long chain family member 1
chr19_-_55149193 0.90 ENST00000587758.5
ENST00000588981.6
ENST00000356783.9
ENST00000291901.12
ENST00000588426.5
ENST00000536926.5
ENST00000588147.5
troponin T1, slow skeletal type
chr16_+_88706458 0.87 ENST00000312060.9
ENST00000453996.7
ENST00000567949.5
ENST00000564921.1
cytosolic thiouridylase subunit 2
chr17_+_48908397 0.87 ENST00000360943.10
ubiquitin conjugating enzyme E2 Z
chr3_-_185498964 0.86 ENST00000296254.3
transmembrane protein 41A
chr7_-_100468063 0.85 ENST00000423266.5
ENST00000456330.1
TSC22 domain family member 4
chr19_+_14072754 0.85 ENST00000587086.2
MISP family member 3
chr22_+_21632751 0.83 ENST00000292779.4
coiled-coil domain containing 116
chr1_+_15153698 0.83 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
transmembrane protein 51
chr3_+_141231770 0.82 ENST00000286353.9
ENST00000502783.5
ENST00000393010.6
ENST00000514680.5
2-phosphoxylose phosphatase 1
chr10_+_69318831 0.81 ENST00000359426.7
hexokinase 1
chr19_+_14433284 0.79 ENST00000242783.11
protein kinase N1
chr19_-_1863497 0.78 ENST00000617223.1
ENST00000250916.6
Kruppel like factor 16
chr14_-_91253925 0.76 ENST00000531499.2
G protein-coupled receptor 68
chr19_+_16661121 0.76 ENST00000187762.7
ENST00000599479.1
transmembrane protein 38A
chr16_-_30526758 0.75 ENST00000562803.1
zinc finger protein 768
chr6_-_159693228 0.74 ENST00000367054.6
ENST00000367055.8
ENST00000538183.7
ENST00000444946.6
ENST00000452684.2
superoxide dismutase 2
chr5_+_150601060 0.74 ENST00000394243.5
synaptopodin
chr12_+_68610858 0.73 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B, member of RAS oncogene family
chrX_-_109625161 0.73 ENST00000372101.3
potassium voltage-gated channel subfamily E regulatory subunit 5
chr20_-_56525925 0.73 ENST00000243913.8
glucosaminyl (N-acetyl) transferase family member 7
chr6_+_127118657 0.72 ENST00000356698.9
R-spondin 3
chr16_+_23678863 0.71 ENST00000300093.9
polo like kinase 1
chr1_+_155208690 0.70 ENST00000368376.8
metaxin 1
chr10_-_47384261 0.69 ENST00000591025.1
ENST00000585316.3
zinc finger protein 488
chr12_-_89525444 0.69 ENST00000549035.1
ENST00000393179.8
POC1 centriolar protein B
chr1_+_45803576 0.68 ENST00000361297.7
microtubule associated serine/threonine kinase 2
chr1_-_22143088 0.68 ENST00000290167.11
Wnt family member 4
chr1_+_155208727 0.67 ENST00000316721.8
metaxin 1
chr20_+_9069076 0.66 ENST00000378473.9
phospholipase C beta 4
chr12_+_108515262 0.65 ENST00000552695.6
ENST00000552758.1
ENST00000361549.2
FIC domain protein adenylyltransferase
chr22_+_18529042 0.65 ENST00000613577.4
transmembrane protein 191B
chr17_-_63700100 0.65 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIM domain containing 2
chr5_+_149141817 0.64 ENST00000504238.5
actin binding LIM protein family member 3
chrX_+_49171889 0.64 ENST00000376327.6
proteolipid protein 2
chr11_+_59172116 0.64 ENST00000227451.4
deltex E3 ubiquitin ligase 4
chr1_+_156114700 0.63 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
lamin A/C
chrX_+_132023294 0.63 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chrX_+_9465011 0.63 ENST00000645353.2
transducin beta like 1 X-linked
chr5_+_149141483 0.63 ENST00000326685.11
ENST00000309868.12
actin binding LIM protein family member 3
chr8_-_141001217 0.62 ENST00000522684.5
ENST00000524357.5
ENST00000521332.5
ENST00000524040.5
ENST00000519881.5
ENST00000520045.5
protein tyrosine kinase 2
chr5_+_149141573 0.62 ENST00000506113.5
actin binding LIM protein family member 3
chr12_-_89526011 0.62 ENST00000313546.8
POC1 centriolar protein B
chr10_+_113709261 0.61 ENST00000672138.1
ENST00000452490.3
caspase 7
chr8_+_133191060 0.61 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
cellular communication network factor 4
chrX_-_15335407 0.60 ENST00000635543.1
ENST00000542278.6
ENST00000482148.6
ENST00000333590.6
ENST00000637296.1
ENST00000634582.1
ENST00000634640.1
phosphatidylinositol glycan anchor biosynthesis class A
chr19_+_10718114 0.60 ENST00000408974.8
dynamin 2
chr20_+_44885679 0.59 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chr3_-_150763093 0.59 ENST00000312960.4
siah E3 ubiquitin protein ligase 2
chr11_-_6481304 0.59 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr6_+_159727561 0.59 ENST00000631126.2
ENST00000337387.4
WT1 associated protein
chr1_+_155209213 0.59 ENST00000609421.1
metaxin 1
chr5_-_157575741 0.57 ENST00000517905.1
ADAM metallopeptidase domain 19
chr1_+_107141022 0.57 ENST00000370067.5
ENST00000370068.6
netrin G1
chr1_-_42456006 0.57 ENST00000372565.8
zinc finger MYND-type containing 12
chr16_+_31074390 0.57 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
zinc finger protein 646
chr16_-_30526518 0.56 ENST00000380412.7
zinc finger protein 768
chr1_+_26111139 0.56 ENST00000619836.4
ENST00000444713.5
PDLIM1 interacting kinase 1 like
chr1_+_156114251 0.56 ENST00000361308.9
lamin A/C
chr21_-_30813270 0.56 ENST00000329621.6
keratin associated protein 8-1
chr6_+_33621313 0.56 ENST00000605930.3
inositol 1,4,5-trisphosphate receptor type 3
chr11_-_6481350 0.56 ENST00000423813.6
ENST00000614314.4
ADP ribosylation factor interacting protein 2
chr14_+_93927358 0.55 ENST00000557000.2
family with sequence similarity 181 member A
chr17_-_38749806 0.55 ENST00000616199.4
polycomb group ring finger 2
chr10_-_98030612 0.55 ENST00000370597.8
cartilage acidic protein 1
chr8_+_31640358 0.54 ENST00000523534.5
neuregulin 1
chr5_+_177303768 0.54 ENST00000303204.9
ENST00000503216.5
PRELI domain containing 1
chr19_+_35154914 0.54 ENST00000423817.7
FXYD domain containing ion transport regulator 5
chr19_+_35154715 0.53 ENST00000392218.6
ENST00000543307.5
ENST00000392219.7
ENST00000541435.6
ENST00000590686.5
ENST00000342879.7
ENST00000588699.5
FXYD domain containing ion transport regulator 5
chr22_+_31082860 0.53 ENST00000619644.4
smoothelin
chr12_+_6199715 0.52 ENST00000382518.6
ENST00000642746.1
ENST00000538834.6
CD9 molecule
chr6_-_30687200 0.52 ENST00000399199.7
protein phosphatase 1 regulatory subunit 18
chr10_+_18400562 0.51 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr5_-_177303675 0.51 ENST00000393611.6
ENST00000303270.6
ENST00000303251.11
RAB24, member RAS oncogene family
chr14_+_75428011 0.50 ENST00000651602.1
ENST00000559060.5
Jun dimerization protein 2
chr19_+_35138993 0.50 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr8_+_737595 0.49 ENST00000637795.2
DLG associated protein 2
chr1_+_149899561 0.48 ENST00000369152.6
bolA family member 1
chr20_-_64107546 0.47 ENST00000684052.1
neuropeptides B and W receptor 2
chr19_+_37907200 0.47 ENST00000222345.11
signal induced proliferation associated 1 like 3
chr4_-_168318770 0.47 ENST00000680771.1
ENST00000514995.2
DExD/H-box helicase 60
chr5_+_172641241 0.47 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr17_+_42682470 0.46 ENST00000264638.9
contactin associated protein 1
chr1_+_206507520 0.46 ENST00000579436.7
Ras association domain family member 5
chr14_+_104801082 0.46 ENST00000342537.8
zinc finger and BTB domain containing 42
chr22_-_18024513 0.45 ENST00000441493.7
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr11_+_24496988 0.45 ENST00000336930.11
leucine zipper protein 2
chr1_-_237004440 0.45 ENST00000464121.3
metallothionein 1H like 1
chr12_+_113057687 0.45 ENST00000257600.3
deltex E3 ubiquitin ligase 1
chrX_+_49171918 0.45 ENST00000376322.7
proteolipid protein 2
chr6_+_20403679 0.45 ENST00000535432.2
E2F transcription factor 3
chr4_-_168318743 0.44 ENST00000393743.8
DExD/H-box helicase 60
chr1_-_40317266 0.44 ENST00000372736.3
ENST00000372748.8
collagen type IX alpha 2 chain
chr1_+_1512137 0.44 ENST00000378756.8
ENST00000378755.9
ATPase family AAA domain containing 3A
chr11_+_24497155 0.44 ENST00000529015.5
ENST00000533227.5
leucine zipper protein 2
chr1_+_206507546 0.43 ENST00000580449.5
ENST00000581503.6
Ras association domain family member 5
chr1_-_23424618 0.43 ENST00000476978.2
transcription elongation factor A3
chr6_-_30686624 0.42 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr11_+_131911396 0.42 ENST00000425719.6
ENST00000374784.5
neurotrimin
chr14_-_88323238 0.42 ENST00000319231.10
potassium two pore domain channel subfamily K member 10
chrX_+_153334146 0.41 ENST00000370249.3
ENST00000650114.2
ENST00000370251.3
zinc finger protein 275
chr12_-_30754927 0.41 ENST00000541765.5
ENST00000537108.5
caprin family member 2
chr21_+_44300038 0.41 ENST00000349048.9
ENST00000628044.1
phosphofructokinase, liver type
chr11_+_10305065 0.40 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
adrenomedullin
chr20_-_52191751 0.40 ENST00000346617.8
ENST00000371515.8
ENST00000371518.6
ENST00000216923.5
ZFP64 zinc finger protein
chr11_-_68213577 0.40 ENST00000402789.5
ENST00000402185.6
ENST00000458496.1
lysine methyltransferase 5B
chr8_+_22604632 0.40 ENST00000308511.8
ENST00000523801.5
ENST00000521301.5
cell cycle and apoptosis regulator 2
chr2_+_101252867 0.40 ENST00000289382.8
CCR4-NOT transcription complex subunit 11
chr3_-_167734915 0.40 ENST00000497056.6
ENST00000473645.6
programmed cell death 10
chr16_-_50681328 0.39 ENST00000300590.7
sorting nexin 20
chr9_-_136205122 0.39 ENST00000371748.10
LIM homeobox 3
chr11_-_66317037 0.39 ENST00000311330.4
CD248 molecule
chr16_-_89816607 0.39 ENST00000563673.5
ENST00000568369.5
ENST00000389301.8
ENST00000534992.5
ENST00000389302.7
ENST00000543736.5
FA complementation group A
chr17_-_65560296 0.39 ENST00000585045.1
ENST00000611991.1
axin 2
chr8_+_22605018 0.39 ENST00000389279.7
cell cycle and apoptosis regulator 2
chr11_-_57324907 0.39 ENST00000358252.8
tankyrase 1 binding protein 1
chr11_+_117328085 0.38 ENST00000527609.5
ENST00000533570.1
centrosomal protein 164
chr19_+_2867327 0.38 ENST00000586426.5
ENST00000307635.3
zinc finger protein 556
chr12_+_110468803 0.38 ENST00000377673.10
family with sequence similarity 216 member A
chr14_-_24081986 0.38 ENST00000560550.1
neural retina leucine zipper
chr1_-_155033778 0.37 ENST00000368424.4
DC-STAMP domain containing 2
chr7_-_16421524 0.37 ENST00000407010.7
CDP-L-ribitol pyrophosphorylase A
chrX_+_30653359 0.37 ENST00000378943.7
ENST00000378946.7
ENST00000427190.6
glycerol kinase
chrX_+_30653478 0.37 ENST00000378945.7
ENST00000378941.4
glycerol kinase
chr14_-_24081928 0.37 ENST00000396995.1
neural retina leucine zipper
chr5_+_150190035 0.36 ENST00000230671.7
ENST00000524041.1
solute carrier family 6 member 7
chr19_-_10339610 0.36 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr7_-_103989649 0.36 ENST00000428762.6
reelin
chr9_+_137255277 0.35 ENST00000343053.6
negative elongation factor complex member B
chr11_-_68213828 0.35 ENST00000405515.5
lysine methyltransferase 5B
chr20_+_46118300 0.35 ENST00000372285.8
ENST00000372276.7
CD40 molecule
chr1_+_7784411 0.35 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr17_+_1724540 0.35 ENST00000419248.5
ENST00000418841.5
ENST00000409644.6
WD repeat domain 81
chr17_-_75261586 0.34 ENST00000580799.2
ENST00000538886.5
ENST00000537686.6
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr3_-_167734832 0.34 ENST00000464360.5
ENST00000492139.5
ENST00000471885.5
ENST00000392750.7
ENST00000470131.5
programmed cell death 10
chr1_-_26960413 0.34 ENST00000320567.6
keratinocyte differentiation factor 1
chr1_-_26960369 0.34 ENST00000616918.1
keratinocyte differentiation factor 1
chr1_+_19644284 0.34 ENST00000375136.8
NBL1, DAN family BMP antagonist
chr14_-_93788475 0.34 ENST00000393140.6
proline rich membrane anchor 1
chr19_+_7395112 0.34 ENST00000319670.14
Rho/Rac guanine nucleotide exchange factor 18
chr22_-_40636689 0.34 ENST00000402042.7
ENST00000355630.10
myocardin related transcription factor A
chr7_+_2354810 0.34 ENST00000360876.9
ENST00000413917.5
ENST00000397011.2
eukaryotic translation initiation factor 3 subunit B
chr15_+_75903870 0.34 ENST00000453211.6
ENST00000308275.8
F-box protein 22
chr20_+_63696643 0.34 ENST00000369996.3
TNF receptor superfamily member 6b
chr19_+_7395166 0.34 ENST00000594665.2
ENST00000617428.4
Rho/Rac guanine nucleotide exchange factor 18
chr11_-_120138104 0.33 ENST00000341846.10
tripartite motif containing 29
chrX_+_96684712 0.33 ENST00000373049.8
diaphanous related formin 2
chr22_+_46296850 0.33 ENST00000454366.2
G2 and S-phase expressed 1
chr2_+_44168866 0.33 ENST00000282412.9
ENST00000409432.7
ENST00000378551.6
ENST00000345249.8
protein phosphatase, Mg2+/Mn2+ dependent 1B
chr1_-_44031446 0.33 ENST00000372310.8
ENST00000466926.1
solute carrier family 6 member 9
chr10_+_113679523 0.33 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr17_-_73311980 0.33 ENST00000439510.2
ENST00000581014.1
ENST00000335793.4
ENST00000579611.1
CDC42 effector protein 4
chr11_+_117327829 0.33 ENST00000533153.5
ENST00000278935.8
ENST00000525416.5
centrosomal protein 164
chr2_+_240625237 0.33 ENST00000407714.1
G protein-coupled receptor 35
chr8_+_133191029 0.32 ENST00000250160.11
cellular communication network factor 4
chr10_+_113679839 0.32 ENST00000369318.8
ENST00000369315.5
caspase 7
chr19_-_6424802 0.32 ENST00000600480.2
KH-type splicing regulatory protein
chr11_+_2444986 0.32 ENST00000155840.12
potassium voltage-gated channel subfamily Q member 1
chr14_+_79279906 0.32 ENST00000428277.6
neurexin 3
chr10_+_131900999 0.32 ENST00000455566.6
protein phosphatase 2 regulatory subunit Bdelta
chr22_+_46150590 0.31 ENST00000262735.9
ENST00000420804.5
peroxisome proliferator activated receptor alpha
chr22_-_38088915 0.31 ENST00000428572.1
BAR/IMD domain containing adaptor protein 2 like 2
chr16_-_1351798 0.31 ENST00000007390.3
TSR3 ribosome maturation factor
chr1_+_172659095 0.31 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr14_-_23010122 0.31 ENST00000397377.5
ENST00000397379.7
ENST00000341470.8
ENST00000555998.5
ENST00000299088.11
ENST00000397376.6
ENST00000553675.5
ENST00000553931.5
ENST00000555575.5
ENST00000553958.5
ENST00000555098.5
ENST00000556419.5
ENST00000553606.5
ENST00000554179.5
ENST00000397382.8
chromosome 14 open reading frame 93
chr12_+_6970904 0.31 ENST00000599672.6
ENST00000539196.2
EMG1 N1-specific pseudouridine methyltransferase
chr15_-_62060371 0.31 ENST00000644861.2
ENST00000645819.1
ENST00000395898.3
vacuolar protein sorting 13 homolog C
chrX_+_7147819 0.31 ENST00000660000.2
steroid sulfatase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0009720 detection of hormone stimulus(GO:0009720)
0.4 2.0 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.4 1.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.3 4.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.3 1.0 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 2.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 1.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.3 1.6 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.2 GO:0060437 lung growth(GO:0060437)
0.2 0.7 GO:0090031 positive regulation of dermatome development(GO:0061184) renal vesicle induction(GO:0072034) positive regulation of steroid hormone biosynthetic process(GO:0090031) regulation of testosterone biosynthetic process(GO:2000224)
0.2 0.9 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 1.9 GO:0034201 response to oleic acid(GO:0034201)
0.2 0.6 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.2 1.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 0.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 2.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2 0.6 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.2 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 0.9 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.5 GO:0048817 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.2 1.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 0.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.4 GO:0036233 glycine import(GO:0036233)
0.1 0.7 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.7 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.4 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.8 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.6 GO:0033590 response to cobalamin(GO:0033590)
0.1 0.7 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 1.7 GO:0070141 response to UV-A(GO:0070141)
0.1 0.3 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 1.2 GO:0002934 desmosome organization(GO:0002934)
0.1 0.7 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.8 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.7 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.6 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.7 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.7 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.5 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.6 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.5 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.8 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.2 GO:0035498 carnosine metabolic process(GO:0035498)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.2 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.1 0.4 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0018963 phthalate metabolic process(GO:0018963)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.2 GO:0003193 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.5 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.2 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.2 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 0.2 GO:0072299 metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.1 0.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 1.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.5 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.8 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.1 GO:1900161 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.9 GO:0008228 opsonization(GO:0008228)
0.0 0.5 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 2.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:0071504 cellular response to heparin(GO:0071504)
0.0 1.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 1.2 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.5 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 1.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.3 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) dopamine catabolic process(GO:0042420) catecholamine catabolic process(GO:0042424)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.1 GO:0061341 cell migration involved in kidney development(GO:0035787) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.6 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.5 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 1.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.3 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 1.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.4 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0044609 DBIRD complex(GO:0044609)
0.2 0.7 GO:0097444 spine apparatus(GO:0097444)
0.2 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.6 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.2 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0032021 NELF complex(GO:0032021)
0.1 1.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.6 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.8 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.2 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 1.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 6.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 7.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.7 2.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 2.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 2.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.0 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.2 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.7 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.8 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.9 GO:0031014 troponin T binding(GO:0031014)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.2 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.0 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.2 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.6 PID ARF 3PATHWAY Arf1 pathway
0.0 2.6 PID ATR PATHWAY ATR signaling pathway
0.0 2.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.5 PID AURORA A PATHWAY Aurora A signaling
0.0 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)