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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TFAP2E

Z-value: 0.41

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Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
TFAP2E
ENSG00000116819.9 TFAP2E

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Ehg38_v1_chr1_+_35573308_35573319-0.404.9e-02Click!

Activity profile of TFAP2E motif

Sorted Z-values of TFAP2E motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_74834113 1.01 ENST00000290573.7
HK2
hexokinase 2
chr11_+_64206663 0.63 ENST00000544997.5
ENST00000345728.10
ENST00000279227.9
FERMT3
fermitin family member 3
chr11_-_61295289 0.45 ENST00000335613.10
VWCE
von Willebrand factor C and EGF domains
chr6_+_7107597 0.43 ENST00000379933.7
ENST00000491191.5
ENST00000471433.5
RREB1
ras responsive element binding protein 1
chr19_+_45001430 0.43 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB
RELB proto-oncogene, NF-kB subunit
chr3_+_105367212 0.38 ENST00000472644.6
ALCAM
activated leukocyte cell adhesion molecule
chr19_+_38304105 0.32 ENST00000588605.5
ENST00000301246.10
C19orf33
chromosome 19 open reading frame 33
chr11_-_35419098 0.31 ENST00000606205.6
ENST00000645303.1
SLC1A2
solute carrier family 1 member 2
chr11_-_35419462 0.31 ENST00000643522.1
SLC1A2
solute carrier family 1 member 2
chr10_-_131981948 0.31 ENST00000633835.1
BNIP3
BCL2 interacting protein 3
chr11_+_82901698 0.30 ENST00000524921.5
ENST00000528759.5
ENST00000525361.5
ENST00000532764.5
ENST00000532589.5
ENST00000533655.6
ENST00000525388.5
DDIAS
DNA damage induced apoptosis suppressor
chr3_+_53161120 0.30 ENST00000394729.6
ENST00000330452.8
ENST00000652449.1
PRKCD
protein kinase C delta
chr19_+_4969105 0.29 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
KDM4B
lysine demethylase 4B
chr11_-_35419213 0.29 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
SLC1A2
solute carrier family 1 member 2
chr19_+_43576800 0.28 ENST00000612042.4
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr3_-_48088800 0.28 ENST00000423088.5
MAP4
microtubule associated protein 4
chr19_-_35490456 0.27 ENST00000338897.4
ENST00000484218.6
KRTDAP
keratinocyte differentiation associated protein
chr17_+_39667964 0.27 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr11_+_118607579 0.25 ENST00000530708.4
PHLDB1
pleckstrin homology like domain family B member 1
chr6_+_31586680 0.25 ENST00000339530.8
LST1
leukocyte specific transcript 1
chr6_+_7107941 0.25 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
RREB1
ras responsive element binding protein 1
chr17_+_39668447 0.25 ENST00000269582.3
ENST00000581428.1
PNMT
phenylethanolamine N-methyltransferase
chr10_+_98134622 0.24 ENST00000370584.7
R3HCC1L
R3H domain and coiled-coil containing 1 like
chr6_+_42564060 0.24 ENST00000372903.6
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr10_+_98134642 0.23 ENST00000298999.8
R3HCC1L
R3H domain and coiled-coil containing 1 like
chr11_-_66289007 0.23 ENST00000431556.6
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr11_-_35420017 0.23 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
SLC1A2
solute carrier family 1 member 2
chr16_+_56589521 0.22 ENST00000200691.5
ENST00000570176.1
MT3
metallothionein 3
chrX_+_49171889 0.22 ENST00000376327.6
PLP2
proteolipid protein 2
chr1_+_8945858 0.22 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
CA6
carbonic anhydrase 6
chr6_+_31586835 0.22 ENST00000211921.11
LST1
leukocyte specific transcript 1
chr11_-_66289125 0.20 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr17_-_33293247 0.20 ENST00000225823.7
ASIC2
acid sensing ion channel subunit 2
chr19_+_48954850 0.20 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BAX
BCL2 associated X, apoptosis regulator
chr6_-_29633056 0.20 ENST00000377016.8
GABBR1
gamma-aminobutyric acid type B receptor subunit 1
chrX_+_132023294 0.20 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
STK26
serine/threonine kinase 26
chr6_+_31586859 0.19 ENST00000433492.5
LST1
leukocyte specific transcript 1
chr11_-_35419542 0.19 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
SLC1A2
solute carrier family 1 member 2
chr6_-_29633171 0.19 ENST00000377034.9
GABBR1
gamma-aminobutyric acid type B receptor subunit 1
chr7_-_23014074 0.18 ENST00000409763.1
ENST00000679826.1
ENST00000409923.5
ENST00000681766.1
FAM126A
family with sequence similarity 126 member A
chr20_+_24469623 0.18 ENST00000376862.4
SYNDIG1
synapse differentiation inducing 1
chr11_-_77411883 0.18 ENST00000528203.5
ENST00000528592.5
ENST00000528633.1
ENST00000529248.5
PAK1
p21 (RAC1) activated kinase 1
chrX_+_49171918 0.18 ENST00000376322.7
PLP2
proteolipid protein 2
chr7_-_23014099 0.17 ENST00000432176.7
ENST00000440481.6
FAM126A
family with sequence similarity 126 member A
chr1_-_40862354 0.17 ENST00000372638.4
CITED4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr3_-_48088824 0.17 ENST00000439356.2
ENST00000395734.7
ENST00000426837.6
MAP4
microtubule associated protein 4
chr10_-_110918934 0.16 ENST00000605742.5
BBIP1
BBSome interacting protein 1
chr5_-_151924824 0.16 ENST00000455880.2
GLRA1
glycine receptor alpha 1
chr7_-_140924699 0.16 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr17_+_30831944 0.16 ENST00000321990.5
ATAD5
ATPase family AAA domain containing 5
chr5_-_151924846 0.15 ENST00000274576.9
GLRA1
glycine receptor alpha 1
chr10_-_77637902 0.15 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr1_+_213989691 0.15 ENST00000607425.1
PROX1
prospero homeobox 1
chr7_-_45088888 0.15 ENST00000490531.3
NACAD
NAC alpha domain containing
chr7_+_148590760 0.15 ENST00000307003.3
C7orf33
chromosome 7 open reading frame 33
chr13_-_26760741 0.15 ENST00000405846.5
GPR12
G protein-coupled receptor 12
chr9_+_4985227 0.15 ENST00000381652.4
JAK2
Janus kinase 2
chr5_+_134648772 0.14 ENST00000398844.7
ENST00000322887.8
SEC24A
SEC24 homolog A, COPII coat complex component
chr3_+_156142962 0.14 ENST00000471742.5
KCNAB1
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr6_+_13272709 0.14 ENST00000379335.8
PHACTR1
phosphatase and actin regulator 1
chr17_+_3723889 0.14 ENST00000325418.5
HASPIN
histone H3 associated protein kinase
chr7_+_35800932 0.14 ENST00000635172.1
ENST00000399034.7
ENST00000350320.10
ENST00000435235.6
ENST00000672279.1
ENST00000634600.1
ENST00000635047.1
SEPTIN7
septin 7
chr10_-_110919146 0.14 ENST00000652396.1
ENST00000423273.5
ENST00000436562.1
ENST00000651952.1
ENST00000448814.7
ENST00000652400.1
ENST00000447005.5
ENST00000454061.5
BBIP1
BBSome interacting protein 1
chrX_-_49079702 0.13 ENST00000636049.1
ENST00000474053.6
ENST00000635003.1
WDR45
WD repeat domain 45
chr11_+_47215032 0.13 ENST00000622090.4
ENST00000378600.7
ENST00000378603.7
DDB2
damage specific DNA binding protein 2
chr22_-_45977154 0.13 ENST00000339464.9
WNT7B
Wnt family member 7B
chr7_+_100867379 0.13 ENST00000200457.9
ENST00000619988.4
TRIP6
thyroid hormone receptor interactor 6
chr11_+_118607598 0.13 ENST00000600882.6
ENST00000356063.9
PHLDB1
pleckstrin homology like domain family B member 1
chr20_+_2840694 0.13 ENST00000380469.7
ENST00000380445.8
ENST00000453689.5
ENST00000417508.1
VPS16
VPS16 core subunit of CORVET and HOPS complexes
chr19_-_38773432 0.13 ENST00000599035.1
ENST00000378626.5
LGALS7
galectin 7
chr4_+_6909775 0.12 ENST00000409757.9
TBC1D14
TBC1 domain family member 14
chr2_+_231708511 0.12 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
PTMA
prothymosin alpha
chr12_-_56630293 0.12 ENST00000546695.5
ENST00000549884.6
BAZ2A
bromodomain adjacent to zinc finger domain 2A
chr13_+_99981775 0.12 ENST00000376335.8
ZIC2
Zic family member 2
chr22_+_31212207 0.12 ENST00000406516.5
ENST00000331728.9
LIMK2
LIM domain kinase 2
chr1_+_150149819 0.12 ENST00000369124.5
PLEKHO1
pleckstrin homology domain containing O1
chr6_-_18264475 0.11 ENST00000515742.2
ENST00000651624.1
ENST00000507591.2
ENST00000652689.1
ENST00000244776.11
ENST00000503715.5
DEK
DEK proto-oncogene
chr4_+_6909444 0.10 ENST00000448507.5
TBC1D14
TBC1 domain family member 14
chrX_-_124963768 0.10 ENST00000371130.7
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr7_-_140924900 0.10 ENST00000646891.1
ENST00000644969.2
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr6_+_42563981 0.10 ENST00000372899.6
ENST00000372901.2
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_201377652 0.10 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
TNNT2
troponin T2, cardiac type
chr8_+_25184758 0.10 ENST00000481100.5
DOCK5
dedicator of cytokinesis 5
chr8_+_17922837 0.10 ENST00000325083.12
PCM1
pericentriolar material 1
chr16_-_75433391 0.10 ENST00000566254.1
ENST00000283882.4
CFDP1
craniofacial development protein 1
chr9_-_15307181 0.09 ENST00000506891.1
ENST00000512701.6
ENST00000380850.8
ENST00000297615.9
TTC39B
tetratricopeptide repeat domain 39B
chr1_-_85048437 0.09 ENST00000341115.8
ENST00000370587.5
ENST00000370589.7
MCOLN3
mucolipin TRP cation channel 3
chr16_+_89948697 0.09 ENST00000567999.5
ENST00000610455.4
ENST00000617948.4
ENST00000566079.5
ENST00000566820.5
ENST00000562578.5
ENST00000563594.6
ENST00000561741.5
ENST00000268676.11
ENST00000562986.5
ENST00000569453.5
ENST00000567884.5
ENST00000569061.5
ENST00000418391.6
ENST00000561959.5
ENST00000567874.5
ENST00000570182.5
ENST00000563795.1
DEF8
differentially expressed in FDCP 8 homolog
chr1_-_11691646 0.09 ENST00000235310.7
MAD2L2
mitotic arrest deficient 2 like 2
chr1_-_11691608 0.09 ENST00000376667.7
MAD2L2
mitotic arrest deficient 2 like 2
chr17_-_76726753 0.09 ENST00000617192.4
JMJD6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr3_+_49554436 0.09 ENST00000296452.5
BSN
bassoon presynaptic cytomatrix protein
chr14_-_25050111 0.08 ENST00000323944.9
STXBP6
syntaxin binding protein 6
chrX_+_116436599 0.08 ENST00000598581.3
SLC6A14
solute carrier family 6 member 14
chr14_-_25049889 0.07 ENST00000419632.6
ENST00000396700.5
STXBP6
syntaxin binding protein 6
chr14_+_103385450 0.07 ENST00000416682.6
MARK3
microtubule affinity regulating kinase 3
chr22_+_31248402 0.07 ENST00000333611.8
ENST00000340552.4
LIMK2
LIM domain kinase 2
chr14_+_103385506 0.07 ENST00000303622.13
MARK3
microtubule affinity regulating kinase 3
chr14_+_20745880 0.07 ENST00000326842.3
EDDM3A
epididymal protein 3A
chrX_+_41085436 0.07 ENST00000324545.9
ENST00000378308.7
USP9X
ubiquitin specific peptidase 9 X-linked
chr7_+_130070518 0.06 ENST00000335420.10
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr1_-_114511160 0.06 ENST00000369543.6
ENST00000358465.7
TRIM33
tripartite motif containing 33
chr18_-_76495191 0.06 ENST00000443185.7
ZNF516
zinc finger protein 516
chr1_-_113812254 0.06 ENST00000616024.4
ENST00000615321.1
RSBN1
round spermatid basic protein 1
chr7_-_100468063 0.05 ENST00000423266.5
ENST00000456330.1
TSC22D4
TSC22 domain family member 4
chr14_+_103385374 0.05 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
MARK3
microtubule affinity regulating kinase 3
chr10_-_77638369 0.05 ENST00000372443.6
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr9_-_109320949 0.05 ENST00000374557.4
EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr2_-_37324826 0.05 ENST00000234179.8
PRKD3
protein kinase D3
chr17_+_76074772 0.05 ENST00000329003.4
GALR2
galanin receptor 2
chr4_+_153466324 0.05 ENST00000409663.7
ENST00000409959.8
TMEM131L
transmembrane 131 like
chr20_+_6767678 0.05 ENST00000378827.5
BMP2
bone morphogenetic protein 2
chr2_+_74514442 0.05 ENST00000233638.8
TLX2
T cell leukemia homeobox 2
chr17_-_35089212 0.05 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr8_+_17922974 0.04 ENST00000517730.5
ENST00000518537.5
ENST00000523055.5
ENST00000519253.5
PCM1
pericentriolar material 1
chr1_+_228208054 0.04 ENST00000284548.16
ENST00000422127.5
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr8_+_124450806 0.04 ENST00000328599.4
TRMT12
tRNA methyltransferase 12 homolog
chrX_+_106802660 0.04 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1D8B
TBC1 domain family member 8B
chr1_-_113812448 0.04 ENST00000612242.4
ENST00000261441.9
RSBN1
round spermatid basic protein 1
chr3_-_55487295 0.04 ENST00000264634.9
WNT5A
Wnt family member 5A
chr12_-_31324129 0.04 ENST00000454658.6
SINHCAF
SIN3-HDAC complex associated factor
chr4_-_81471855 0.04 ENST00000436139.6
ENST00000613784.1
RASGEF1B
RasGEF domain family member 1B
chr17_-_68601357 0.04 ENST00000592554.2
FAM20A
FAM20A golgi associated secretory pathway pseudokinase
chr17_-_44915486 0.03 ENST00000638281.1
ENST00000588316.1
ENST00000588735.3
ENST00000639277.1
ENST00000253408.11
ENST00000435360.8
ENST00000586793.6
ENST00000588037.1
ENST00000592320.6
GFAP
glial fibrillary acidic protein
chr3_+_4493442 0.03 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr5_-_176610104 0.03 ENST00000303991.5
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr2_-_23927107 0.03 ENST00000238789.10
ATAD2B
ATPase family AAA domain containing 2B
chr11_-_47848539 0.03 ENST00000526870.1
NUP160
nucleoporin 160
chr6_-_87702221 0.03 ENST00000257787.6
AKIRIN2
akirin 2
chr7_+_151085858 0.02 ENST00000463381.5
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr11_+_116829898 0.02 ENST00000227667.8
ENST00000375345.3
APOC3
apolipoprotein C3
chr19_+_35704540 0.02 ENST00000392197.7
ENST00000426659.6
ZBTB32
zinc finger and BTB domain containing 32
chr12_+_67269328 0.02 ENST00000545606.6
CAND1
cullin associated and neddylation dissociated 1
chr4_-_81471898 0.02 ENST00000335927.11
ENST00000264400.7
ENST00000504863.1
RASGEF1B
RasGEF domain family member 1B
chr14_+_24368020 0.02 ENST00000554050.5
ENST00000554903.1
ENST00000250373.9
ENST00000554779.1
ENST00000553708.5
NFATC4
nuclear factor of activated T cells 4
chr9_+_125261788 0.02 ENST00000461379.5
ENST00000297933.11
ENST00000394084.5
ENST00000394105.6
ENST00000470056.5
ENST00000394083.6
ENST00000495955.5
ENST00000467750.5
GAPVD1
GTPase activating protein and VPS9 domains 1
chr3_+_4493340 0.02 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr1_-_43368039 0.02 ENST00000413844.3
ELOVL1
ELOVL fatty acid elongase 1
chr2_+_218859794 0.01 ENST00000233948.4
WNT6
Wnt family member 6
chr5_+_138753412 0.01 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
CTNNA1
catenin alpha 1
chr16_-_381935 0.01 ENST00000431232.7
ENST00000250930.7
PGAP6
post-glycosylphosphatidylinositol attachment to proteins 6
chr9_+_130265773 0.01 ENST00000624552.3
HMCN2
hemicentin 2
chr9_+_130265745 0.01 ENST00000683500.1
HMCN2
hemicentin 2
chr7_+_29194757 0.01 ENST00000222792.11
CHN2
chimerin 2
chr3_+_42654470 0.01 ENST00000680014.1
ZBTB47
zinc finger and BTB domain containing 47
chr11_-_35419899 0.01 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
SLC1A2
solute carrier family 1 member 2
chr11_-_71252492 0.01 ENST00000601538.6
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr19_+_8390316 0.01 ENST00000328024.11
ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr1_+_152970646 0.01 ENST00000328051.3
SPRR4
small proline rich protein 4
chr10_+_91220603 0.00 ENST00000336126.6
PCGF5
polycomb group ring finger 5
chr19_-_43465596 0.00 ENST00000244333.4
LYPD3
LY6/PLAUR domain containing 3
chr1_+_22563460 0.00 ENST00000166244.8
ENST00000374644.8
EPHA8
EPH receptor A8
chr2_-_240892007 0.00 ENST00000402775.6
ENST00000307486.12
MAB21L4
mab-21 like 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 1.0 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 0.5 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 0.3 GO:2000753 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.1 1.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:2000296 lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:1902512 B cell selection(GO:0002339) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.6 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.1 GO:1902724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.0 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.0 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0044691 tooth eruption(GO:0044691)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0033746 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN