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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TFCP2L1

Z-value: 0.82

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Transcription factors associated with TFCP2L1

Gene Symbol Gene ID Gene Info
TFCP2L1
ENSG00000115112.8 TFCP2L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2L1hg38_v1_chr2_-_121285194_1212852090.252.3e-01Click!

Activity profile of TFCP2L1 motif

Sorted Z-values of TFCP2L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2L1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_19712823 2.69 ENST00000396085.6
ENST00000349880.9
NAV2
neuron navigator 2
chr6_-_31582415 2.07 ENST00000429299.3
ENST00000446745.2
LTB
lymphotoxin beta
chr8_+_53851786 1.74 ENST00000297313.8
ENST00000344277.10
RGS20
regulator of G protein signaling 20
chr2_-_10448318 1.73 ENST00000234111.9
ODC1
ornithine decarboxylase 1
chr15_-_35085295 1.62 ENST00000528386.4
NANOGP8
Nanog homeobox retrogene P8
chr16_-_65121930 1.41 ENST00000566827.5
ENST00000394156.7
ENST00000268603.9
ENST00000562998.1
CDH11
cadherin 11
chr1_+_205256189 1.40 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr14_+_96204679 1.33 ENST00000542454.2
ENST00000539359.1
ENST00000554311.2
ENST00000553811.1
BDKRB2
ENSG00000258691.1
bradykinin receptor B2
novel protein
chr19_-_4338786 1.28 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
STAP2
signal transducing adaptor family member 2
chr7_+_151341764 1.26 ENST00000413040.7
ENST00000470229.6
ENST00000568733.6
NUB1
negative regulator of ubiquitin like proteins 1
chr1_+_205257180 1.24 ENST00000330675.12
TMCC2
transmembrane and coiled-coil domain family 2
chr21_-_15064934 1.14 ENST00000400199.5
ENST00000400202.5
ENST00000318948.7
NRIP1
nuclear receptor interacting protein 1
chr7_+_66205325 1.12 ENST00000304842.6
ENST00000649664.1
TPST1
tyrosylprotein sulfotransferase 1
chr16_-_11587162 1.09 ENST00000570904.5
ENST00000574701.5
LITAF
lipopolysaccharide induced TNF factor
chr22_-_37427433 1.06 ENST00000452946.1
ENST00000402918.7
ELFN2
ELFN2
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr12_-_48004496 1.00 ENST00000337299.7
COL2A1
collagen type II alpha 1 chain
chr1_-_111200633 0.97 ENST00000357640.9
DENND2D
DENN domain containing 2D
chr3_+_173584433 0.96 ENST00000361589.8
NLGN1
neuroligin 1
chr6_+_31587185 0.96 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
LST1
leukocyte specific transcript 1
chr14_+_32077068 0.94 ENST00000396582.6
ARHGAP5
Rho GTPase activating protein 5
chr10_-_73625951 0.91 ENST00000433394.1
ENST00000422491.7
USP54
ubiquitin specific peptidase 54
chr12_-_121274510 0.80 ENST00000392474.6
CAMKK2
calcium/calmodulin dependent protein kinase kinase 2
chr9_+_88991440 0.77 ENST00000358157.3
S1PR3
sphingosine-1-phosphate receptor 3
chr20_+_56629296 0.73 ENST00000201031.3
TFAP2C
transcription factor AP-2 gamma
chr10_-_119536533 0.72 ENST00000392865.5
RGS10
regulator of G protein signaling 10
chr16_+_84294853 0.72 ENST00000219454.10
WFDC1
WAP four-disulfide core domain 1
chr3_-_49929800 0.71 ENST00000455683.6
MON1A
MON1 homolog A, secretory trafficking associated
chr16_+_84294823 0.70 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr2_+_46941199 0.70 ENST00000319190.11
ENST00000394850.6
TTC7A
tetratricopeptide repeat domain 7A
chr19_-_12140315 0.64 ENST00000418866.1
ENST00000600335.5
ENST00000334213.10
ZNF20
zinc finger protein 20
chr14_+_32077280 0.64 ENST00000432921.5
ENST00000345122.8
ENST00000433497.5
ARHGAP5
Rho GTPase activating protein 5
chr1_-_201115372 0.62 ENST00000458416.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr11_+_96389985 0.58 ENST00000332349.5
JRKL
JRK like
chr3_-_50340933 0.58 ENST00000616212.4
RASSF1
Ras association domain family member 1
chr11_+_62881686 0.58 ENST00000536981.6
ENST00000539891.6
SLC3A2
solute carrier family 3 member 2
chr3_-_50340804 0.56 ENST00000359365.9
ENST00000357043.6
RASSF1
Ras association domain family member 1
chr20_-_44651683 0.56 ENST00000537820.1
ENST00000372874.9
ADA
adenosine deaminase
chr10_+_122163426 0.56 ENST00000360561.7
TACC2
transforming acidic coiled-coil containing protein 2
chr1_-_161550591 0.56 ENST00000367967.7
ENST00000436743.6
ENST00000442336.1
FCGR3A
Fc fragment of IgG receptor IIIa
chr10_+_122163590 0.55 ENST00000368999.5
TACC2
transforming acidic coiled-coil containing protein 2
chr7_-_113086150 0.54 ENST00000449591.2
GPR85
G protein-coupled receptor 85
chr10_+_122163672 0.53 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr19_+_35139440 0.52 ENST00000455515.6
FXYD1
FXYD domain containing ion transport regulator 1
chr1_-_225941212 0.52 ENST00000366820.10
LEFTY2
left-right determination factor 2
chr19_+_35138993 0.52 ENST00000612146.4
ENST00000589209.5
FXYD1
FXYD domain containing ion transport regulator 1
chr17_+_7355123 0.52 ENST00000389982.8
ENST00000576060.6
ENST00000330767.4
TMEM95
transmembrane protein 95
chr9_-_128067310 0.52 ENST00000373078.5
NAIF1
nuclear apoptosis inducing factor 1
chr3_+_38039199 0.51 ENST00000346219.7
ENST00000308059.11
DLEC1
DLEC1 cilia and flagella associated protein
chr5_-_161546970 0.51 ENST00000675303.1
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr5_-_161546671 0.50 ENST00000517547.5
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr1_-_225941383 0.48 ENST00000420304.6
LEFTY2
left-right determination factor 2
chr1_-_153565535 0.48 ENST00000368707.5
S100A2
S100 calcium binding protein A2
chr21_+_42653585 0.48 ENST00000291539.11
PDE9A
phosphodiesterase 9A
chr10_-_122845850 0.48 ENST00000392790.6
CUZD1
CUB and zona pellucida like domains 1
chr20_-_49913693 0.48 ENST00000422556.1
SPATA2
spermatogenesis associated 2
chr2_+_11746576 0.48 ENST00000256720.6
ENST00000674199.1
ENST00000441684.5
ENST00000423495.1
LPIN1
lipin 1
chr17_-_1492660 0.48 ENST00000648651.1
MYO1C
myosin IC
chr7_-_100158679 0.47 ENST00000456769.5
ENST00000316937.8
TRAPPC14
trafficking protein particle complex 14
chr18_+_58362467 0.45 ENST00000675101.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr12_-_120904337 0.45 ENST00000353487.7
SPPL3
signal peptide peptidase like 3
chr1_-_161549793 0.44 ENST00000443193.6
FCGR3A
Fc fragment of IgG receptor IIIa
chr22_+_21015027 0.44 ENST00000413302.6
ENST00000401443.5
P2RX6
purinergic receptor P2X 6
chr3_+_63967738 0.44 ENST00000484332.1
ATXN7
ataxin 7
chr11_-_57322197 0.43 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1
chr19_+_41219235 0.43 ENST00000359092.7
AXL
AXL receptor tyrosine kinase
chr14_+_58637934 0.43 ENST00000395153.8
DACT1
dishevelled binding antagonist of beta catenin 1
chr17_-_76027212 0.42 ENST00000586740.1
EVPL
envoplakin
chrX_+_137566119 0.42 ENST00000287538.10
ZIC3
Zic family member 3
chr5_-_143403297 0.42 ENST00000415690.6
NR3C1
nuclear receptor subfamily 3 group C member 1
chr22_-_22508702 0.42 ENST00000626650.3
ZNF280B
zinc finger protein 280B
chr4_-_173530219 0.42 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr7_-_113086815 0.42 ENST00000424100.2
GPR85
G protein-coupled receptor 85
chr1_-_161549892 0.42 ENST00000426740.7
FCGR3A
Fc fragment of IgG receptor IIIa
chr22_-_38088915 0.41 ENST00000428572.1
BAIAP2L2
BAR/IMD domain containing adaptor protein 2 like 2
chr2_+_240625237 0.41 ENST00000407714.1
GPR35
G protein-coupled receptor 35
chr2_+_71068636 0.40 ENST00000244204.11
ENST00000533981.5
NAGK
N-acetylglucosamine kinase
chr5_-_59356962 0.40 ENST00000405755.6
PDE4D
phosphodiesterase 4D
chr2_+_71068603 0.39 ENST00000443938.6
NAGK
N-acetylglucosamine kinase
chr12_-_52652207 0.38 ENST00000309680.4
KRT2
keratin 2
chr19_+_35138778 0.37 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD1
ENSG00000221857.7
FXYD domain containing ion transport regulator 1
novel transcript
chr14_-_68979076 0.37 ENST00000538545.6
ENST00000684639.1
ACTN1
actinin alpha 1
chr12_-_57772087 0.37 ENST00000324871.12
ENST00000257848.7
METTL1
methyltransferase like 1
chr2_+_202073282 0.37 ENST00000459709.5
KIAA2012
KIAA2012
chr12_-_119803383 0.36 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
CIT
citron rho-interacting serine/threonine kinase
chr14_-_68937942 0.36 ENST00000684182.1
ACTN1
actinin alpha 1
chr12_-_53232182 0.36 ENST00000425354.7
ENST00000546717.1
ENST00000394426.5
RARG
retinoic acid receptor gamma
chr1_-_204359885 0.36 ENST00000414478.1
ENST00000272203.8
PLEKHA6
pleckstrin homology domain containing A6
chr14_-_68979251 0.36 ENST00000438964.6
ENST00000679147.1
ACTN1
actinin alpha 1
chr6_+_150683593 0.35 ENST00000644968.1
PLEKHG1
pleckstrin homology and RhoGEF domain containing G1
chr3_-_50503597 0.35 ENST00000266039.7
ENST00000424201.7
CACNA2D2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
chr22_+_25199856 0.35 ENST00000215855.7
ENST00000404334.1
CRYBB3
crystallin beta B3
chr3_-_52409783 0.35 ENST00000470173.1
ENST00000296288.9
ENST00000460680.6
BAP1
BRCA1 associated protein 1
chr6_-_31112566 0.35 ENST00000259870.4
C6orf15
chromosome 6 open reading frame 15
chr2_+_202073249 0.34 ENST00000498697.3
KIAA2012
KIAA2012
chr1_-_207032749 0.34 ENST00000359470.6
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr17_-_82648428 0.34 ENST00000392325.9
WDR45B
WD repeat domain 45B
chr5_-_179806830 0.34 ENST00000292591.12
MGAT4B
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
chrX_+_70455093 0.33 ENST00000542398.1
DLG3
discs large MAGUK scaffold protein 3
chr17_-_28951285 0.33 ENST00000577226.5
PHF12
PHD finger protein 12
chr12_+_57772648 0.33 ENST00000333012.5
EEF1AKMT3
EEF1A lysine methyltransferase 3
chr8_-_27992624 0.32 ENST00000524352.5
SCARA5
scavenger receptor class A member 5
chr8_+_54457927 0.32 ENST00000297316.5
SOX17
SRY-box transcription factor 17
chr1_+_193059587 0.32 ENST00000400968.7
ENST00000415442.2
ENST00000506303.1
RO60
Ro60, Y RNA binding protein
chr12_+_7789393 0.31 ENST00000229307.9
NANOG
Nanog homeobox
chr19_+_38930916 0.31 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr22_+_20131781 0.31 ENST00000334554.12
ENST00000320602.11
ENST00000405930.3
ZDHHC8
zinc finger DHHC-type palmitoyltransferase 8
chr15_+_60004305 0.31 ENST00000396057.6
FOXB1
forkhead box B1
chr11_-_86069043 0.31 ENST00000532317.5
ENST00000528256.1
ENST00000393346.8
ENST00000526033.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr19_-_6481769 0.30 ENST00000381480.7
ENST00000543576.5
ENST00000590173.5
DENND1C
DENN domain containing 1C
chr22_-_42857194 0.30 ENST00000437119.6
ENST00000454099.5
ENST00000263245.10
ARFGAP3
ADP ribosylation factor GTPase activating protein 3
chr12_+_57772587 0.29 ENST00000300209.13
EEF1AKMT3
EEF1A lysine methyltransferase 3
chr3_-_48188356 0.29 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
CDC25A
cell division cycle 25A
chr2_+_11724333 0.29 ENST00000425416.6
ENST00000396097.5
LPIN1
lipin 1
chr12_+_52079700 0.29 ENST00000546390.2
SMIM41
small integral membrane protein 41
chr12_-_110445540 0.28 ENST00000547365.1
ARPC3
actin related protein 2/3 complex subunit 3
chr5_-_141618914 0.28 ENST00000518047.5
DIAPH1
diaphanous related formin 1
chr3_-_122416035 0.28 ENST00000330689.6
WDR5B
WD repeat domain 5B
chr11_-_78188588 0.28 ENST00000526208.5
ENST00000529350.1
ENST00000530018.5
ENST00000528776.1
ENST00000340067.4
KCTD21
potassium channel tetramerization domain containing 21
chr1_+_193059448 0.28 ENST00000432079.5
RO60
Ro60, Y RNA binding protein
chr15_+_89690804 0.28 ENST00000268130.12
ENST00000560294.5
ENST00000558000.1
WDR93
WD repeat domain 93
chr12_+_123633739 0.28 ENST00000618160.4
GTF2H3
general transcription factor IIH subunit 3
chr2_-_20012661 0.28 ENST00000421259.2
ENST00000407540.8
MATN3
matrilin 3
chr19_+_41219177 0.28 ENST00000301178.9
AXL
AXL receptor tyrosine kinase
chr19_-_12551426 0.27 ENST00000416136.1
ENST00000339282.12
ENST00000596193.1
ENST00000428311.1
ZNF564
ENSG00000196826.7
zinc finger protein 564
novel zinc finger protein
chr19_-_12294819 0.27 ENST00000355684.6
ENST00000356109.10
ZNF44
zinc finger protein 44
chr11_+_100687279 0.27 ENST00000298815.13
ARHGAP42
Rho GTPase activating protein 42
chr1_-_156248038 0.27 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
PAQR6
progestin and adipoQ receptor family member 6
chr18_-_48950960 0.27 ENST00000262158.8
SMAD7
SMAD family member 7
chr18_+_23949847 0.26 ENST00000588004.1
LAMA3
laminin subunit alpha 3
chr7_-_122995700 0.26 ENST00000249284.3
TAS2R16
taste 2 receptor member 16
chr2_+_231781669 0.26 ENST00000410024.5
ENST00000611614.4
ENST00000409295.5
ENST00000409091.5
COPS7B
COP9 signalosome subunit 7B
chr11_+_111245725 0.26 ENST00000280325.7
C11orf53
chromosome 11 open reading frame 53
chr5_-_161546708 0.26 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr11_-_128867268 0.26 ENST00000392665.6
ENST00000392666.6
KCNJ1
potassium inwardly rectifying channel subfamily J member 1
chr17_-_1628341 0.26 ENST00000571650.5
SLC43A2
solute carrier family 43 member 2
chr1_+_151540299 0.26 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
TUFT1
tuftelin 1
chr1_+_110150480 0.25 ENST00000331565.5
SLC6A17
solute carrier family 6 member 17
chr11_-_128867364 0.25 ENST00000440599.6
ENST00000324036.7
KCNJ1
potassium inwardly rectifying channel subfamily J member 1
chr5_-_141619049 0.25 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
DIAPH1
diaphanous related formin 1
chr5_+_176238365 0.25 ENST00000341199.10
ENST00000430704.6
ENST00000443967.5
ENST00000429602.7
SIMC1
SUMO interacting motifs containing 1
chr12_+_123633819 0.25 ENST00000539994.5
ENST00000538845.5
ENST00000228955.11
ENST00000543341.7
ENST00000536375.5
GTF2H3
general transcription factor IIH subunit 3
chr1_+_26863140 0.25 ENST00000339276.6
SFN
stratifin
chr5_-_141618957 0.25 ENST00000389054.8
DIAPH1
diaphanous related formin 1
chr8_-_131040211 0.24 ENST00000377928.7
ADCY8
adenylate cyclase 8
chr16_-_81096163 0.24 ENST00000566566.2
ENST00000569885.6
ENST00000561801.2
ENST00000639689.1
ENST00000638948.1
ENST00000564536.2
ENST00000638192.1
ENST00000640345.1
GCSH
ENSG00000260643.2
ENSG00000284512.1
glycine cleavage system protein H
novel protein
novel protein
chr3_-_50567711 0.23 ENST00000357203.8
C3orf18
chromosome 3 open reading frame 18
chr1_-_156248013 0.23 ENST00000368270.2
PAQR6
progestin and adipoQ receptor family member 6
chr1_+_116111395 0.23 ENST00000684484.1
ENST00000369500.4
MAB21L3
mab-21 like 3
chr5_+_96663010 0.23 ENST00000506811.5
ENST00000514055.5
ENST00000508608.6
CAST
calpastatin
chr3_-_50567646 0.23 ENST00000426034.5
ENST00000441239.5
C3orf18
chromosome 3 open reading frame 18
chr3_+_184362991 0.23 ENST00000430783.5
POLR2H
RNA polymerase II, I and III subunit H
chr1_+_204870831 0.23 ENST00000404076.5
ENST00000539706.6
NFASC
neurofascin
chr7_+_151956379 0.23 ENST00000431418.6
GALNTL5
polypeptide N-acetylgalactosaminyltransferase like 5
chr5_-_177311882 0.22 ENST00000513169.1
ENST00000423571.6
ENST00000502529.1
ENST00000427908.6
MXD3
MAX dimerization protein 3
chr10_-_70785371 0.22 ENST00000456372.4
ENST00000299290.5
TBATA
thymus, brain and testes associated
chr11_-_119423162 0.22 ENST00000284240.10
ENST00000524970.5
THY1
Thy-1 cell surface antigen
chr7_+_151956440 0.22 ENST00000392800.7
ENST00000616416.4
GALNTL5
polypeptide N-acetylgalactosaminyltransferase like 5
chr19_+_18612848 0.22 ENST00000262817.8
TMEM59L
transmembrane protein 59 like
chr8_-_131040890 0.22 ENST00000286355.10
ADCY8
adenylate cyclase 8
chr9_+_68780029 0.21 ENST00000394264.7
PABIR1
PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1
chr7_-_140479476 0.21 ENST00000443720.6
ENST00000255977.7
MKRN1
makorin ring finger protein 1
chr12_+_53097656 0.21 ENST00000301464.4
IGFBP6
insulin like growth factor binding protein 6
chr2_+_233251694 0.21 ENST00000417017.5
ENST00000392020.8
ENST00000392018.1
ATG16L1
autophagy related 16 like 1
chr12_-_48004467 0.21 ENST00000380518.8
COL2A1
collagen type II alpha 1 chain
chr2_+_233251571 0.21 ENST00000347464.9
ENST00000444735.5
ENST00000373525.9
ENST00000392017.9
ENST00000419681.5
ATG16L1
autophagy related 16 like 1
chr5_-_140557414 0.21 ENST00000336283.9
SRA1
steroid receptor RNA activator 1
chr17_-_28951443 0.20 ENST00000268756.7
ENST00000332830.9
ENST00000584685.1
PHF12
PHD finger protein 12
chr22_+_31160171 0.20 ENST00000326132.11
ENST00000426256.6
ENST00000266252.8
RNF185
ring finger protein 185
chr1_-_161132423 0.20 ENST00000458050.6
DEDD
death effector domain containing
chr11_+_78188871 0.20 ENST00000528910.5
ENST00000529308.6
USP35
ubiquitin specific peptidase 35
chr19_-_4065732 0.20 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr22_+_22734577 0.19 ENST00000390310.3
IGLV2-18
immunoglobulin lambda variable 2-18
chr12_+_14419136 0.19 ENST00000545769.1
ENST00000428217.6
ENST00000396279.2
ENST00000542514.5
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr20_+_45406035 0.19 ENST00000372723.7
ENST00000372722.7
DBNDD2
dysbindin domain containing 2
chr6_-_18155053 0.19 ENST00000309983.5
TPMT
thiopurine S-methyltransferase
chr4_-_56435581 0.19 ENST00000264220.6
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr8_-_143986425 0.19 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
PARP10
poly(ADP-ribose) polymerase family member 10
chr13_-_36131286 0.19 ENST00000255448.8
ENST00000379892.4
DCLK1
doublecortin like kinase 1
chrX_-_50200988 0.19 ENST00000358526.7
AKAP4
A-kinase anchoring protein 4
chr16_+_30699155 0.19 ENST00000262518.9
SRCAP
Snf2 related CREBBP activator protein
chr5_-_140043069 0.18 ENST00000289409.8
ENST00000358522.7
ENST00000289422.11
ENST00000541337.5
ENST00000361474.6
NRG2
neuregulin 2
chr8_+_116766497 0.18 ENST00000517814.1
ENST00000309822.7
ENST00000517820.1
UTP23
UTP23 small subunit processome component
chr22_-_38755458 0.18 ENST00000405510.5
ENST00000433561.5
SUN2
Sad1 and UNC84 domain containing 2
chr5_+_163437569 0.18 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
CCNG1
cyclin G1
chr7_+_43926419 0.18 ENST00000222402.8
ENST00000446008.5
UBE2D4
ubiquitin conjugating enzyme E2 D4 (putative)
chr10_-_126388455 0.18 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM12
ADAM metallopeptidase domain 12
chr7_-_128405930 0.18 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
IMPDH1
inosine monophosphate dehydrogenase 1
chrX_-_107717054 0.18 ENST00000503515.1
ENST00000372397.6
TSC22D3
TSC22 domain family member 3
chr16_+_22008083 0.17 ENST00000542527.7
ENST00000569656.5
ENST00000562695.1
MOSMO
modulator of smoothened
chr9_+_85941121 0.17 ENST00000361671.10
NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit
chr20_+_13221257 0.17 ENST00000262487.5
ISM1
isthmin 1
chr4_-_173334385 0.17 ENST00000446922.6
HMGB2
high mobility group box 2
chr17_+_16415553 0.17 ENST00000338560.12
TRPV2
transient receptor potential cation channel subfamily V member 2
chr19_+_23117018 0.17 ENST00000597761.7
ZNF730
zinc finger protein 730
chr11_-_33161461 0.17 ENST00000323959.9
ENST00000431742.2
ENST00000524827.6
CSTF3
cleavage stimulation factor subunit 3
chr16_+_89508367 0.17 ENST00000643649.1
ENST00000643307.1
ENST00000566371.6
ENST00000645897.1
ENST00000644781.1
ENST00000645063.1
ENST00000645818.2
ENST00000646716.1
ENST00000268704.7
ENST00000341316.6
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin
chr5_+_150671588 0.17 ENST00000523553.1
MYOZ3
myozenin 3
chr1_-_161038907 0.17 ENST00000318289.14
ENST00000368023.7
ENST00000423014.3
ENST00000368024.5
TSTD1
thiosulfate sulfurtransferase like domain containing 1
chr1_+_50106265 0.16 ENST00000357083.8
ELAVL4
ELAV like RNA binding protein 4
chr4_+_82430563 0.16 ENST00000273920.8
ENOPH1
enolase-phosphatase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.4 1.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 1.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.3 0.3 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.2 1.0 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 1.4 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 2.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.6 GO:0070256 germinal center B cell differentiation(GO:0002314) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) xanthine metabolic process(GO:0046110) negative regulation of mucus secretion(GO:0070256)
0.1 0.8 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.8 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.8 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.3 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828) cardiac cell fate determination(GO:0060913)
0.1 0.9 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.7 GO:0048549 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.4 GO:0061032 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.1 1.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 2.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.2 GO:0060174 limb bud formation(GO:0060174)
0.1 0.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.4 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.5 GO:1902962 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.2 GO:1902232 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0015820 leucine transport(GO:0015820)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 2.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.2 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 1.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0097694 regulation of telomere maintenance via semi-conservative replication(GO:0032213) negative regulation of telomere maintenance via semi-conservative replication(GO:0032214) establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.0 1.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:1904349 positive regulation of eating behavior(GO:1904000) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770)
0.0 0.3 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0043366 beta selection(GO:0043366)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:1990086 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 1.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:0045654 DNA topological change(GO:0006265) positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.3 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.4 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.1 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.9 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.5 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 3.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.7 GO:0033643 host cell part(GO:0033643)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 1.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 0.8 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 1.7 GO:0019864 IgG binding(GO:0019864)
0.1 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.2 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 1.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 2.0 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.0 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 2.5 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects