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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TGIF1

Z-value: 0.66

Motif logo

Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.22 TGIF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg38_v1_chr18_+_3449413_3449619-0.213.1e-01Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_+_70169516 2.20 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr1_+_99646025 2.12 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr7_+_30911845 1.80 ENST00000652696.1
ENST00000311813.11
aquaporin 1 (Colton blood group)
chr18_+_44697118 1.76 ENST00000677077.1
SET binding protein 1
chr15_-_70702273 1.67 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr15_+_57376497 1.62 ENST00000281282.6
cingulin like 1
chr4_+_42397473 1.56 ENST00000319234.5
shisa family member 3
chr2_+_33134620 1.19 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr2_+_33134579 1.18 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr3_-_18424533 1.18 ENST00000417717.6
SATB homeobox 1
chr9_-_130043154 1.09 ENST00000355681.3
ENST00000446176.7
ENST00000443566.6
ENST00000420781.5
formin binding protein 1
chr2_+_172821575 1.07 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr20_-_40689228 1.06 ENST00000373313.3
MAF bZIP transcription factor B
chr14_-_105168753 1.02 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr2_+_172860038 1.02 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr17_-_55732074 1.01 ENST00000575734.5
transmembrane protein 100
chr21_+_44573724 0.97 ENST00000622352.3
ENST00000400374.4
ENST00000616689.2
keratin associated protein 10-4
chr3_+_37975773 0.83 ENST00000436654.1
CTD small phosphatase like
chr9_+_34652167 0.83 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr8_-_92017637 0.80 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr6_-_13487593 0.80 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr14_+_76761453 0.78 ENST00000167106.9
vasohibin 1
chr8_-_6563044 0.73 ENST00000338312.10
angiopoietin 2
chr17_-_67996428 0.73 ENST00000580729.3
chromosome 17 open reading frame 58
chr8_-_6563238 0.72 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr14_+_61529005 0.71 ENST00000556347.1
novel protein
chr8_-_6563409 0.70 ENST00000325203.9
angiopoietin 2
chr4_-_113761724 0.69 ENST00000511664.6
calcium/calmodulin dependent protein kinase II delta
chr4_-_113761441 0.68 ENST00000394524.7
calcium/calmodulin dependent protein kinase II delta
chr11_-_65557740 0.67 ENST00000526927.5
latent transforming growth factor beta binding protein 3
chr9_+_2159672 0.66 ENST00000634343.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_-_68955332 0.66 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr3_-_122793772 0.64 ENST00000306103.3
HSPB1 associated protein 1
chr12_-_25195074 0.64 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr3_-_15798184 0.63 ENST00000624145.3
ankyrin repeat domain 28
chr21_-_34615103 0.61 ENST00000313806.9
regulator of calcineurin 1
chr8_-_29263063 0.60 ENST00000524189.6
kinesin family member 13B
chr6_-_83709019 0.59 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
synaptosome associated protein 91
chr18_-_55302613 0.59 ENST00000561831.7
transcription factor 4
chr9_-_97697297 0.58 ENST00000375128.5
XPA, DNA damage recognition and repair factor
chr2_+_135586250 0.57 ENST00000410054.5
ENST00000628915.2
R3H domain containing 1
chr6_-_83709141 0.57 ENST00000521743.5
synaptosome associated protein 91
chr4_-_88284747 0.57 ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr9_+_131190119 0.55 ENST00000483497.6
nucleoporin 214
chr2_+_33436304 0.54 ENST00000402538.7
RAS guanyl releasing protein 3
chrX_+_9786420 0.54 ENST00000380913.8
shroom family member 2
chr11_+_87037915 0.53 ENST00000526733.5
ENST00000305494.6
ENST00000532959.5
transmembrane protein 135
chr14_-_95516616 0.53 ENST00000682763.1
spectrin repeat containing nuclear envelope family member 3
chr1_+_66533575 0.53 ENST00000684751.1
ENST00000683291.1
ENST00000682054.1
ENST00000435165.3
ENST00000684539.1
ENST00000681971.1
ENST00000682476.1
ENST00000684168.1
ENST00000371039.5
SH3GL interacting endocytic adaptor 1
chr3_-_15797930 0.52 ENST00000683139.1
ankyrin repeat domain 28
chr9_+_2159850 0.52 ENST00000416751.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_63204436 0.51 ENST00000316754.8
ras homolog family member J
chrX_+_102712438 0.51 ENST00000486814.2
ENST00000535209.6
ENST00000543253.6
ENST00000332262.10
ENST00000483720.6
G protein-coupled receptor associated sorting protein 2
chr3_+_45026296 0.51 ENST00000296130.5
C-type lectin domain family 3 member B
chr16_-_67183948 0.50 ENST00000561621.5
ENST00000563902.2
ENST00000290881.11
KIAA0895 like
chr5_-_95284535 0.50 ENST00000515393.5
multiple C2 and transmembrane domain containing 1
chr9_+_128098304 0.50 ENST00000373064.9
solute carrier family 25 member 25
chr17_-_73092657 0.48 ENST00000580557.5
ENST00000579732.5
ENST00000578620.1
ENST00000542342.6
ENST00000255559.7
ENST00000579018.5
solute carrier family 39 member 11
chr20_+_36214373 0.48 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chr7_-_132576493 0.48 ENST00000321063.8
plexin A4
chr20_+_43945677 0.47 ENST00000358131.5
TOX high mobility group box family member 2
chr8_+_11809135 0.46 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr21_-_44592505 0.46 ENST00000400368.1
keratin associated protein 10-6
chr11_-_63768762 0.46 ENST00000433688.2
chromosome 11 open reading frame 95
chr6_+_18387326 0.45 ENST00000259939.4
ring finger protein 144B
chr6_-_10414985 0.45 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr1_-_230978796 0.45 ENST00000522821.5
ENST00000366662.8
ENST00000366661.9
ENST00000522399.1
tetratricopeptide repeat domain 13
chr17_+_4498866 0.44 ENST00000329078.8
sphingolipid transporter 2
chr6_-_10415043 0.44 ENST00000379613.10
transcription factor AP-2 alpha
chr5_-_78985288 0.43 ENST00000264914.10
arylsulfatase B
chr2_+_233060295 0.43 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr3_-_56775657 0.43 ENST00000413728.6
Rho guanine nucleotide exchange factor 3
chr8_-_81483226 0.43 ENST00000256104.5
fatty acid binding protein 4
chr19_-_39335999 0.41 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr17_-_81911128 0.41 ENST00000573927.5
ENST00000331285.7
ENST00000572157.1
phosphate cytidylyltransferase 2, ethanolamine
chr10_+_92848461 0.39 ENST00000443748.6
ENST00000371543.5
ENST00000260762.10
exocyst complex component 6
chr3_-_101513175 0.39 ENST00000394091.5
ENST00000394094.6
ENST00000394095.7
ENST00000348610.3
ENST00000314261.11
SUMO specific peptidase 7
chr14_+_23988884 0.39 ENST00000558753.5
ENST00000537912.5
dehydrogenase/reductase 4 like 2
chr8_+_22589240 0.38 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr16_-_57186053 0.38 ENST00000565760.5
ENST00000570184.1
ENST00000562324.5
proteasome activator subunit 3 interacting protein 1
chr17_-_35795592 0.38 ENST00000615136.4
ENST00000605424.6
ENST00000612672.1
matrix metallopeptidase 28
chr6_+_25652272 0.37 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr1_+_6555301 0.37 ENST00000333172.11
ENST00000351136.7
taste 1 receptor member 1
chr10_-_48274567 0.37 ENST00000636244.1
ENST00000374201.8
FERM and PDZ domain containing 2
chr3_+_63911929 0.36 ENST00000487717.5
ataxin 7
chrX_+_136205982 0.36 ENST00000628568.1
four and a half LIM domains 1
chr20_-_51802433 0.36 ENST00000395997.3
spalt like transcription factor 4
chr8_-_41665200 0.36 ENST00000335651.6
ankyrin 1
chr19_+_48469354 0.36 ENST00000452733.7
ENST00000641098.1
cytohesin 2
chrX_-_135296024 0.35 ENST00000370764.1
zinc finger protein 75D
chr7_-_94655993 0.35 ENST00000647110.1
ENST00000647048.1
ENST00000643020.1
ENST00000644682.1
ENST00000646119.1
ENST00000646265.1
ENST00000645445.1
ENST00000647334.1
ENST00000645262.1
ENST00000428696.7
ENST00000647096.1
ENST00000642394.1
ENST00000645725.1
ENST00000647351.1
ENST00000646943.1
ENST00000648936.2
ENST00000642707.1
ENST00000645109.1
ENST00000646489.1
ENST00000642933.1
ENST00000643128.1
ENST00000445866.7
ENST00000645101.1
ENST00000644116.1
ENST00000642441.1
ENST00000646879.1
ENST00000647018.1
sarcoglycan epsilon
chr3_+_43286512 0.34 ENST00000454177.5
ENST00000429705.6
ENST00000296088.12
ENST00000437827.1
SNF related kinase
chr3_+_112562059 0.34 ENST00000261034.6
solute carrier family 35 member A5
chr9_-_16728165 0.34 ENST00000603713.5
ENST00000603313.5
basonuclin 2
chr2_+_24491860 0.33 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr1_+_228208024 0.33 ENST00000570156.7
ENST00000680850.1
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr7_+_92057602 0.33 ENST00000491695.2
A-kinase anchoring protein 9
chr9_-_16727980 0.32 ENST00000418777.5
ENST00000468187.6
basonuclin 2
chr3_+_112562030 0.32 ENST00000468642.5
ENST00000492406.6
solute carrier family 35 member A5
chr7_-_148883474 0.32 ENST00000476773.5
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_-_76692181 0.32 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr12_+_15322257 0.31 ENST00000674316.1
protein tyrosine phosphatase receptor type O
chr22_-_37486357 0.30 ENST00000356998.8
ENST00000416983.7
ENST00000424765.2
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_150067668 0.30 ENST00000611412.4
ENST00000644510.2
ENST00000643611.1
vacuolar protein sorting 45 homolog
chr1_+_150067820 0.30 ENST00000419023.3
ENST00000644526.1
vacuolar protein sorting 45 homolog
chr7_-_80512041 0.29 ENST00000398291.4
G protein subunit alpha transducin 3
chr1_-_151006795 0.29 ENST00000312210.9
ENST00000683666.1
MINDY lysine 48 deubiquitinase 1
chr19_+_48872412 0.29 ENST00000200453.6
protein phosphatase 1 regulatory subunit 15A
chr1_-_151006471 0.29 ENST00000493834.2
MINDY lysine 48 deubiquitinase 1
chr2_-_196926670 0.29 ENST00000354764.9
post-GPI attachment to proteins inositol deacylase 1
chr11_+_111977300 0.28 ENST00000615255.1
DIX domain containing 1
chr3_-_27722699 0.28 ENST00000461503.2
eomesodermin
chr12_+_15322529 0.28 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr17_-_81911200 0.28 ENST00000570391.5
phosphate cytidylyltransferase 2, ethanolamine
chr1_-_151006404 0.28 ENST00000622754.4
MINDY lysine 48 deubiquitinase 1
chr14_+_38207893 0.27 ENST00000267377.3
somatostatin receptor 1
chr2_+_201116143 0.27 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr12_+_19440578 0.27 ENST00000360995.8
AE binding protein 2
chr4_+_127965394 0.27 ENST00000645843.2
ENST00000388795.9
abhydrolase domain containing 18
chr17_-_3513768 0.26 ENST00000570318.1
ENST00000541913.5
spermatogenesis associated 22
chr10_+_84245038 0.26 ENST00000650682.1
ENST00000358110.7
ENST00000651237.1
ENST00000652122.1
ENST00000652092.2
ENST00000359452.9
ENST00000483744.6
retinal G protein coupled receptor
chr15_-_42548763 0.26 ENST00000563454.5
ENST00000397130.8
ENST00000570160.1
ENST00000323443.6
leucine rich repeat containing 57
chr22_-_49825900 0.26 ENST00000404034.5
bromodomain containing 1
chr2_-_200864561 0.26 ENST00000434813.3
CDC like kinase 1
chr11_+_842807 0.26 ENST00000397411.6
tetraspanin 4
chr14_+_92513766 0.25 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
Ras and Rab interactor 3
chr3_-_184017863 0.25 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr17_+_28042839 0.25 ENST00000582037.2
nemo like kinase
chr2_+_201116238 0.25 ENST00000342795.9
CASP8 and FADD like apoptosis regulator
chr9_+_113444725 0.25 ENST00000374140.6
regulator of G protein signaling 3
chr9_-_35812238 0.25 ENST00000396638.7
ENST00000340291.6
sperm associated antigen 8
chr12_+_25195252 0.25 ENST00000555711.6
ENST00000554266.6
ENST00000556351.6
ENST00000556927.6
ENST00000556402.6
ENST00000553788.6
electron transfer flavoprotein regulatory factor 1
chr17_+_76738012 0.25 ENST00000590514.5
major facilitator superfamily domain containing 11
chr11_+_111976902 0.25 ENST00000614104.4
DIX domain containing 1
chr2_-_200864643 0.24 ENST00000321356.9
CDC like kinase 1
chr12_+_101594849 0.24 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chrX_+_130339886 0.24 ENST00000543953.5
ENST00000612248.4
ENST00000424447.5
ENST00000545805.6
solute carrier family 25 member 14
chr2_-_200864670 0.24 ENST00000621181.4
CDC like kinase 1
chrX_+_130339941 0.24 ENST00000218197.9
solute carrier family 25 member 14
chr6_+_17600273 0.24 ENST00000259963.4
family with sequence similarity 8 member A1
chr1_+_150067279 0.24 ENST00000643970.1
ENST00000535106.5
ENST00000369128.9
vacuolar protein sorting 45 homolog
chr11_+_6390439 0.24 ENST00000530395.1
ENST00000342245.9
ENST00000527275.5
sphingomyelin phosphodiesterase 1
chr10_-_3785179 0.24 ENST00000469435.1
Kruppel like factor 6
chr10_-_96357155 0.23 ENST00000536387.5
oligodendrocytic myelin paranodal and inner loop protein
chr4_-_148444674 0.23 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr16_+_69105636 0.23 ENST00000569188.6
hyaluronan synthase 3
chr11_+_46295126 0.23 ENST00000534787.1
cAMP responsive element binding protein 3 like 1
chr2_-_55917699 0.23 ENST00000634374.1
EGF containing fibulin extracellular matrix protein 1
chr11_+_104036624 0.23 ENST00000302259.5
DNA damage inducible 1 homolog 1
chr6_+_29306626 0.22 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr7_+_95772506 0.22 ENST00000537881.5
ENST00000447467.6
ENST00000524053.5
ENST00000324972.10
ENST00000630942.2
ENST00000437599.5
ENST00000359388.8
ENST00000413338.5
dynein cytoplasmic 1 intermediate chain 1
chrX_-_100731504 0.22 ENST00000372989.5
ENST00000276141.10
synaptotagmin like 4
chr4_+_127965267 0.22 ENST00000398965.5
abhydrolase domain containing 18
chr7_+_120951116 0.22 ENST00000431467.1
inhibitor of growth family member 3
chr14_-_21526312 0.22 ENST00000537235.2
spalt like transcription factor 2
chr12_-_75209701 0.22 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr11_+_842928 0.22 ENST00000397408.5
tetraspanin 4
chr3_-_129161034 0.22 ENST00000418265.1
ENST00000393292.7
ENST00000273541.12
ENST00000393295.8
ISY1-RAB43 readthrough
ISY1 splicing factor homolog
chr17_+_28319149 0.21 ENST00000226230.8
ENST00000583381.5
ENST00000582113.1
ENST00000582384.1
transmembrane protein 97
chr6_-_53510445 0.21 ENST00000509541.5
glutamate-cysteine ligase catalytic subunit
chr11_-_6405405 0.21 ENST00000608645.5
ENST00000618005.4
ENST00000610474.4
ENST00000608394.5
ENST00000529519.5
amyloid beta precursor protein binding family B member 1
chr6_-_33746848 0.21 ENST00000634274.1
ENST00000293756.5
ENST00000451316.6
inositol hexakisphosphate kinase 3
chr1_+_152970646 0.21 ENST00000328051.3
small proline rich protein 4
chr4_-_127965133 0.21 ENST00000641558.1
ENST00000641590.1
ENST00000641503.1
ENST00000641482.1
ENST00000641743.1
ENST00000641369.1
ENST00000641949.1
ENST00000641695.1
ENST00000641509.1
ENST00000641243.1
ENST00000641686.2
ENST00000641690.1
ENST00000641228.1
ENST00000642042.1
major facilitator superfamily domain containing 8
chr4_+_107989880 0.21 ENST00000309522.8
ENST00000403312.6
ENST00000638559.1
ENST00000682373.1
hydroxyacyl-CoA dehydrogenase
chr20_+_44401397 0.21 ENST00000682427.1
ENST00000681977.1
ENST00000684136.1
ENST00000684046.1
ENST00000684476.1
ENST00000619550.5
ENST00000682169.1
hepatocyte nuclear factor 4 alpha
chr10_-_11532275 0.21 ENST00000277575.5
USP6 N-terminal like
chr4_+_127965361 0.21 ENST00000444616.5
abhydrolase domain containing 18
chr2_-_241150264 0.21 ENST00000405260.5
PAS domain containing serine/threonine kinase
chr19_+_39268394 0.20 ENST00000331982.6
interferon lambda 2
chr12_+_40224956 0.20 ENST00000298910.12
ENST00000343742.6
leucine rich repeat kinase 2
chr15_-_65792283 0.20 ENST00000443035.8
ENST00000564674.5
DENN domain containing 4A
chr14_+_99684283 0.20 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr3_-_3179674 0.20 ENST00000424814.5
ENST00000450014.1
ENST00000231948.9
ENST00000432408.6
ENST00000639284.1
cereblon
chr3_+_52794768 0.20 ENST00000621946.4
ENST00000416872.6
ENST00000449956.2
inter-alpha-trypsin inhibitor heavy chain 3
chr12_-_14961256 0.20 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr17_-_41572052 0.20 ENST00000588431.1
ENST00000246662.9
keratin 9
chr20_+_4686320 0.20 ENST00000430350.2
prion protein
chr19_-_20039492 0.20 ENST00000397165.7
zinc finger protein 682
chr17_-_74546082 0.20 ENST00000330793.2
CD300c molecule
chr4_+_107989714 0.20 ENST00000505878.4
ENST00000603302.5
ENST00000638621.1
hydroxyacyl-CoA dehydrogenase
chr19_-_20039443 0.20 ENST00000595736.1
ENST00000593468.5
ENST00000596019.5
zinc finger protein 682
chr4_-_127965204 0.19 ENST00000513559.6
ENST00000641186.1
ENST00000641393.1
major facilitator superfamily domain containing 8
chr10_-_30059510 0.19 ENST00000375377.2
junctional cadherin 5 associated
chr4_+_185209577 0.19 ENST00000652585.1
sorting nexin 25
chr11_+_842824 0.19 ENST00000397396.5
ENST00000397397.7
tetraspanin 4
chr1_-_16018005 0.19 ENST00000406363.2
ENST00000411503.5
ENST00000311890.14
ENST00000487046.1
heat shock protein family B (small) member 7
chr20_-_51802509 0.19 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr1_+_13389632 0.19 ENST00000376098.4
PRAME family member 17
chr19_+_41397803 0.19 ENST00000269980.7
ENST00000542943.5
ENST00000457836.6
branched chain keto acid dehydrogenase E1 subunit alpha
chr20_+_36573458 0.18 ENST00000373874.6
TGFB induced factor homeobox 2
chr6_-_118710065 0.18 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chr15_+_75043263 0.18 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr11_-_73976952 0.18 ENST00000545212.1
uncoupling protein 2
chr19_-_20039205 0.18 ENST00000358523.9
ENST00000397162.5
ENST00000601100.5
zinc finger protein 682
chr6_+_24775413 0.18 ENST00000378054.6
ENST00000620958.4
ENST00000476555.5
geminin DNA replication inhibitor
chr2_+_37084486 0.18 ENST00000281932.6
ENST00000674370.2
G-patch domain containing 11
chr11_-_842508 0.18 ENST00000322028.5
RNA polymerase II, I and III subunit L
chr17_-_59155235 0.18 ENST00000581068.5
spindle and kinetochore associated complex subunit 2
chr9_+_72628020 0.18 ENST00000646619.1
transmembrane channel like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.6 1.8 GO:0033326 nitric oxide transport(GO:0030185) cerebrospinal fluid secretion(GO:0033326) cellular response to mercury ion(GO:0071288) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.6 2.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 2.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.1 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 0.8 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.7 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 0.9 GO:0003409 optic cup structural organization(GO:0003409)
0.2 0.6 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 0.5 GO:0061580 colon epithelial cell migration(GO:0061580)
0.2 1.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 0.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.5 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.4 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.7 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 1.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.7 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.0 GO:0009912 auditory receptor cell fate commitment(GO:0009912) gamma-delta T cell differentiation(GO:0042492) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.3 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.2 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.2 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.5 GO:0015866 ADP transport(GO:0015866)
0.0 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.4 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.4 GO:0055091 ornithine metabolic process(GO:0006591) phospholipid homeostasis(GO:0055091)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.7 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.0 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0032094 response to food(GO:0032094)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:2000078 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 1.4 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:0010157 response to chlorate(GO:0010157)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.5 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 0.5 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 2.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.6 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0071438 intercellular canaliculus(GO:0046581) invadopodium membrane(GO:0071438)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.7 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0050436 microfibril binding(GO:0050436)
0.4 1.8 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.7 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.9 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.5 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 2.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.4 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 2.1 GO:0031432 titin binding(GO:0031432)
0.1 0.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.2 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 1.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0043208 fucose binding(GO:0042806) glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 1.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 2.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1