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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TLX1_NFIC

Z-value: 1.24

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Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
TLX1
ENSG00000107807.13 TLX1
NFIC
ENSG00000141905.19 NFIC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIChg38_v1_chr19_+_3359563_33596830.232.6e-01Click!
TLX1hg38_v1_chr10_+_101131284_1011313210.019.5e-01Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_78620432 12.92 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
IFI44L
interferon induced protein 44 like
chr1_+_78620722 11.17 ENST00000679848.1
IFI44L
interferon induced protein 44 like
chr15_+_88638947 5.62 ENST00000559876.2
ISG20
interferon stimulated exonuclease gene 20
chr17_+_76376581 5.01 ENST00000591651.5
ENST00000545180.5
SPHK1
sphingosine kinase 1
chr17_+_79034185 4.89 ENST00000581774.5
C1QTNF1
C1q and TNF related 1
chr15_+_88639009 4.78 ENST00000306072.10
ISG20
interferon stimulated exonuclease gene 20
chr1_+_109910485 4.49 ENST00000525659.5
CSF1
colony stimulating factor 1
chr8_-_79767462 4.20 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr6_-_31582415 4.07 ENST00000429299.3
ENST00000446745.2
LTB
lymphotoxin beta
chr1_+_109910840 4.03 ENST00000329608.11
ENST00000488198.5
CSF1
colony stimulating factor 1
chr7_+_143381907 3.89 ENST00000392910.6
ZYX
zyxin
chr8_-_79767843 3.73 ENST00000337919.9
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr3_-_98901656 3.62 ENST00000326840.11
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr7_+_143381561 3.51 ENST00000354434.8
ZYX
zyxin
chr1_+_100719734 3.50 ENST00000370119.8
ENST00000294728.7
ENST00000347652.6
ENST00000370115.1
VCAM1
vascular cell adhesion molecule 1
chr1_+_109910986 3.47 ENST00000369801.1
CSF1
colony stimulating factor 1
chr1_-_173050931 3.42 ENST00000404377.5
TNFSF18
TNF superfamily member 18
chr11_-_128587551 3.40 ENST00000392668.8
ETS1
ETS proto-oncogene 1, transcription factor
chr6_+_137871208 3.29 ENST00000614035.4
ENST00000621150.3
ENST00000619035.4
ENST00000615468.4
ENST00000620204.3
TNFAIP3
TNF alpha induced protein 3
chr2_+_102104563 3.14 ENST00000409589.5
ENST00000409329.5
IL1R1
interleukin 1 receptor type 1
chr15_-_72231583 2.95 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
PKM
pyruvate kinase M1/2
chr15_+_70936487 2.89 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr15_-_72231113 2.87 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
PKM
pyruvate kinase M1/2
chr21_-_36480060 2.73 ENST00000399137.5
CLDN14
claudin 14
chr1_-_173205543 2.48 ENST00000367718.5
TNFSF4
TNF superfamily member 4
chr6_-_43627302 2.20 ENST00000307114.11
GTPBP2
GTP binding protein 2
chr19_+_10286971 2.18 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr11_-_57322197 2.16 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1
chr14_+_73237493 2.14 ENST00000340738.9
ENST00000644200.2
PAPLN
papilin, proteoglycan like sulfated glycoprotein
chr12_+_65824475 2.12 ENST00000403681.7
HMGA2
high mobility group AT-hook 2
chr5_+_114362286 2.10 ENST00000610748.4
ENST00000264773.7
KCNN2
potassium calcium-activated channel subfamily N member 2
chr19_+_10286944 2.09 ENST00000380770.5
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr7_+_116524984 2.02 ENST00000614113.5
ENST00000393470.1
CAV1
caveolin 1
chr7_-_81770122 2.00 ENST00000423064.7
HGF
hepatocyte growth factor
chr1_+_112674416 1.96 ENST00000413052.6
ENST00000369645.5
MOV10
Mov10 RISC complex RNA helicase
chr1_-_201023694 1.91 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
KIF21B
kinesin family member 21B
chr17_-_50397472 1.87 ENST00000576448.1
ENST00000225972.8
LRRC59
leucine rich repeat containing 59
chr2_+_26848199 1.85 ENST00000401478.5
DPYSL5
dihydropyrimidinase like 5
chr1_+_112674722 1.80 ENST00000357443.2
MOV10
Mov10 RISC complex RNA helicase
chr20_+_59835853 1.78 ENST00000492611.5
PHACTR3
phosphatase and actin regulator 3
chr15_+_45635017 1.77 ENST00000260324.12
SQOR
sulfide quinone oxidoreductase
chr1_+_112674649 1.73 ENST00000369644.5
MOV10
Mov10 RISC complex RNA helicase
chr20_+_59676661 1.71 ENST00000355648.8
PHACTR3
phosphatase and actin regulator 3
chr16_+_57619942 1.66 ENST00000568908.5
ENST00000568909.5
ENST00000566778.5
ENST00000561988.5
ADGRG1
adhesion G protein-coupled receptor G1
chr9_-_127724873 1.66 ENST00000419060.5
PTRH1
peptidyl-tRNA hydrolase 1 homolog
chr4_-_119628007 1.65 ENST00000420633.1
ENST00000394439.5
PDE5A
phosphodiesterase 5A
chr3_+_63967738 1.56 ENST00000484332.1
ATXN7
ataxin 7
chr19_+_15673069 1.53 ENST00000550308.6
ENST00000551607.5
CYP4F12
cytochrome P450 family 4 subfamily F member 12
chr5_-_139482285 1.47 ENST00000652110.1
STING1
stimulator of interferon response cGAMP interactor 1
chr2_-_37671633 1.44 ENST00000295324.4
CDC42EP3
CDC42 effector protein 3
chr17_-_43833137 1.38 ENST00000398389.9
MPP3
membrane palmitoylated protein 3
chr5_-_139482341 1.38 ENST00000651699.1
STING1
stimulator of interferon response cGAMP interactor 1
chr11_-_111766359 1.38 ENST00000341980.10
ENST00000311129.9
ENST00000393055.6
ENST00000426998.6
ENST00000527614.6
PPP2R1B
protein phosphatase 2 scaffold subunit Abeta
chr1_-_94927079 1.37 ENST00000370206.9
ENST00000394202.8
CNN3
calponin 3
chr5_-_139482173 1.36 ENST00000652271.1
STING1
stimulator of interferon response cGAMP interactor 1
chr22_-_36817001 1.29 ENST00000406910.6
ENST00000417718.7
PVALB
parvalbumin
chr1_+_38991239 1.29 ENST00000432648.8
ENST00000446189.6
ENST00000372984.8
AKIRIN1
akirin 1
chr1_+_179293760 1.27 ENST00000367619.8
SOAT1
sterol O-acyltransferase 1
chr1_+_179293714 1.27 ENST00000540564.5
ENST00000539888.5
SOAT1
sterol O-acyltransferase 1
chr1_-_31798755 1.25 ENST00000452755.6
SPOCD1
SPOC domain containing 1
chr19_-_43656616 1.24 ENST00000593447.5
PLAUR
plasminogen activator, urokinase receptor
chr7_+_116525028 1.22 ENST00000341049.7
CAV1
caveolin 1
chr6_-_53148822 1.22 ENST00000259803.8
GCM1
glial cells missing transcription factor 1
chr17_+_7558296 1.21 ENST00000438470.5
ENST00000436057.5
TNFSF13
TNF superfamily member 13
chr19_-_40882226 1.19 ENST00000301146.9
CYP2A7
cytochrome P450 family 2 subfamily A member 7
chr2_+_26848093 1.16 ENST00000288699.11
DPYSL5
dihydropyrimidinase like 5
chr20_-_45891200 1.16 ENST00000372518.5
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr15_-_68432151 1.16 ENST00000423218.6
ENST00000315757.9
ITGA11
integrin subunit alpha 11
chr8_+_105318428 1.13 ENST00000407775.7
ZFPM2
zinc finger protein, FOG family member 2
chr4_+_139301478 1.11 ENST00000296543.10
ENST00000398947.1
NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr17_+_7440738 1.09 ENST00000575398.5
ENST00000575082.5
FGF11
fibroblast growth factor 11
chr19_+_46303599 1.08 ENST00000300862.7
HIF3A
hypoxia inducible factor 3 subunit alpha
chr8_+_119416427 1.06 ENST00000259526.4
CCN3
cellular communication network factor 3
chr16_-_46763237 1.06 ENST00000536476.5
MYLK3
myosin light chain kinase 3
chr7_+_86644829 1.06 ENST00000439827.1
ENST00000421579.1
GRM3
glutamate metabotropic receptor 3
chr2_-_37672178 1.05 ENST00000457889.1
CDC42EP3
CDC42 effector protein 3
chr11_+_62190212 1.04 ENST00000306238.3
SCGB1D1
secretoglobin family 1D member 1
chr16_+_57628507 1.02 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
ADGRG1
adhesion G protein-coupled receptor G1
chr19_-_6737565 1.01 ENST00000601716.1
ENST00000264080.11
GPR108
G protein-coupled receptor 108
chr20_+_62667803 1.00 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family member 4A1
chr9_+_133534697 0.98 ENST00000651351.2
ADAMTSL2
ADAMTS like 2
chr11_-_30586272 0.97 ENST00000448418.6
MPPED2
metallophosphoesterase domain containing 2
chr1_+_156126160 0.97 ENST00000448611.6
ENST00000368297.5
LMNA
lamin A/C
chr2_+_233388146 0.95 ENST00000409813.7
DGKD
diacylglycerol kinase delta
chr11_-_30586866 0.94 ENST00000528686.2
MPPED2
metallophosphoesterase domain containing 2
chr11_-_35419462 0.93 ENST00000643522.1
SLC1A2
solute carrier family 1 member 2
chr16_-_69351778 0.92 ENST00000288025.4
TMED6
transmembrane p24 trafficking protein 6
chr1_+_78649818 0.92 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr12_-_108632073 0.89 ENST00000228463.6
SELPLG
selectin P ligand
chr11_-_64996963 0.88 ENST00000301887.9
ENST00000534177.1
BATF2
basic leucine zipper ATF-like transcription factor 2
chr11_-_35419213 0.88 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
SLC1A2
solute carrier family 1 member 2
chr5_-_116536458 0.86 ENST00000510263.5
SEMA6A
semaphorin 6A
chr12_+_65824403 0.86 ENST00000393578.7
ENST00000425208.6
ENST00000536545.5
ENST00000354636.7
HMGA2
high mobility group AT-hook 2
chr9_+_133534807 0.86 ENST00000393060.1
ADAMTSL2
ADAMTS like 2
chr11_-_35420050 0.85 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
SLC1A2
solute carrier family 1 member 2
chr3_-_58627596 0.85 ENST00000474531.5
ENST00000465970.1
FAM107A
family with sequence similarity 107 member A
chr16_+_30650728 0.84 ENST00000568754.5
PRR14
proline rich 14
chr22_-_36817510 0.84 ENST00000443735.1
PVALB
parvalbumin
chr11_+_5389377 0.83 ENST00000328611.5
OR51M1
olfactory receptor family 51 subfamily M member 1
chr11_+_72227881 0.82 ENST00000538751.5
ENST00000541756.5
INPPL1
inositol polyphosphate phosphatase like 1
chr4_-_119627631 0.82 ENST00000264805.9
PDE5A
phosphodiesterase 5A
chr11_-_35419899 0.82 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
SLC1A2
solute carrier family 1 member 2
chr5_+_52787899 0.81 ENST00000274311.3
ENST00000282588.7
PELO
ITGA1
pelota mRNA surveillance and ribosome rescue factor
integrin subunit alpha 1
chr9_+_35673917 0.80 ENST00000617161.1
ENST00000378357.9
CA9
carbonic anhydrase 9
chr12_-_52814106 0.79 ENST00000551956.2
KRT4
keratin 4
chr3_-_58627567 0.77 ENST00000649301.1
FAM107A
family with sequence similarity 107 member A
chrX_+_47078330 0.77 ENST00000457380.5
RGN
regucalcin
chr7_+_128715385 0.76 ENST00000315184.9
FAM71F1
family with sequence similarity 71 member F1
chr5_+_68292562 0.76 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr11_-_35420017 0.75 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
SLC1A2
solute carrier family 1 member 2
chr11_-_10693740 0.75 ENST00000423302.7
IRAG1
inositol 1,4,5-triphosphate receptor associated 1
chr11_+_18396266 0.74 ENST00000540430.5
ENST00000379412.9
LDHA
lactate dehydrogenase A
chr19_+_11541125 0.73 ENST00000587087.5
CNN1
calponin 1
chr3_-_191282383 0.72 ENST00000427544.6
UTS2B
urotensin 2B
chr1_+_156126525 0.71 ENST00000504687.6
ENST00000473598.6
LMNA
lamin A/C
chr1_-_112704921 0.70 ENST00000414971.1
ENST00000534717.5
RHOC
ras homolog family member C
chr11_-_10693955 0.70 ENST00000547195.5
IRAG1
inositol 1,4,5-triphosphate receptor associated 1
chr11_-_10693616 0.70 ENST00000541483.5
IRAG1
inositol 1,4,5-triphosphate receptor associated 1
chrX_-_84502442 0.70 ENST00000297977.9
ENST00000506585.6
ENST00000373177.3
ENST00000449553.2
HDX
highly divergent homeobox
chr12_+_111034136 0.69 ENST00000261726.11
CUX2
cut like homeobox 2
chr2_+_26848424 0.68 ENST00000431402.5
ENST00000614712.4
ENST00000434719.1
DPYSL5
dihydropyrimidinase like 5
chr6_+_135181361 0.68 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB
MYB proto-oncogene, transcription factor
chr7_+_150368189 0.68 ENST00000519397.1
ENST00000479668.5
REPIN1
replication initiator 1
chr17_+_7308339 0.68 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr22_+_24607638 0.67 ENST00000432867.5
GGT1
gamma-glutamyltransferase 1
chr2_+_6877768 0.66 ENST00000382040.4
RSAD2
radical S-adenosyl methionine domain containing 2
chr3_-_12158901 0.66 ENST00000287814.5
TIMP4
TIMP metallopeptidase inhibitor 4
chr8_-_42207557 0.66 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
PLAT
plasminogen activator, tissue type
chr1_-_27490045 0.65 ENST00000536657.1
WASF2
WASP family member 2
chr8_-_42207667 0.65 ENST00000352041.7
ENST00000679151.1
ENST00000679300.1
PLAT
plasminogen activator, tissue type
chr19_+_49361783 0.65 ENST00000594268.1
DKKL1
dickkopf like acrosomal protein 1
chr17_-_75878542 0.65 ENST00000254816.6
TRIM47
tripartite motif containing 47
chr6_+_36954729 0.64 ENST00000373674.4
PI16
peptidase inhibitor 16
chr22_-_30564889 0.63 ENST00000401975.5
ENST00000428682.5
ENST00000423299.5
GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_+_122779707 0.63 ENST00000368444.8
ENST00000356535.4
FABP7
fatty acid binding protein 7
chr3_+_48223479 0.62 ENST00000652295.2
CAMP
cathelicidin antimicrobial peptide
chr12_+_100473951 0.61 ENST00000648861.1
ENST00000546380.1
NR1H4
nuclear receptor subfamily 1 group H member 4
chr11_-_30586344 0.61 ENST00000358117.10
MPPED2
metallophosphoesterase domain containing 2
chr11_+_75151095 0.59 ENST00000289575.10
ENST00000525650.5
ENST00000454962.6
SLCO2B1
solute carrier organic anion transporter family member 2B1
chr16_+_23755015 0.59 ENST00000300113.3
CHP2
calcineurin like EF-hand protein 2
chr12_+_57128656 0.59 ENST00000338962.8
LRP1
LDL receptor related protein 1
chr12_+_57128475 0.58 ENST00000243077.8
ENST00000553277.5
LRP1
LDL receptor related protein 1
chr1_-_153565535 0.58 ENST00000368707.5
S100A2
S100 calcium binding protein A2
chr11_-_85686123 0.57 ENST00000316398.5
CCDC89
coiled-coil domain containing 89
chr2_+_184598520 0.57 ENST00000302277.7
ZNF804A
zinc finger protein 804A
chr1_+_172452885 0.57 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr17_-_69327091 0.56 ENST00000592568.1
ENST00000392676.8
ABCA5
ATP binding cassette subfamily A member 5
chr1_+_100538131 0.56 ENST00000315033.5
GPR88
G protein-coupled receptor 88
chrX_+_47078434 0.56 ENST00000397180.6
RGN
regucalcin
chr3_-_155854375 0.56 ENST00000643144.2
ENST00000359479.7
ENST00000646424.1
SLC33A1
solute carrier family 33 member 1
chr3_+_48223325 0.56 ENST00000296435.2
CAMP
cathelicidin antimicrobial peptide
chr1_-_243255170 0.55 ENST00000366542.6
CEP170
centrosomal protein 170
chr1_+_224183262 0.55 ENST00000391877.3
DEGS1
delta 4-desaturase, sphingolipid 1
chr17_+_7558712 0.54 ENST00000338784.9
ENST00000625791.2
TNFSF13
TNF superfamily member 13
chr2_-_74507664 0.54 ENST00000233630.11
PCGF1
polycomb group ring finger 1
chr18_-_77017042 0.53 ENST00000359645.7
ENST00000397875.7
ENST00000397869.7
ENST00000578193.5
ENST00000578873.5
ENST00000397866.8
ENST00000528160.1
ENST00000527041.1
ENST00000526111.5
ENST00000397865.9
ENST00000382582.7
MBP
myelin basic protein
chr5_-_1886938 0.53 ENST00000613726.4
IRX4
iroquois homeobox 4
chr2_+_112055557 0.53 ENST00000650799.1
ENST00000452614.5
TMEM87B
transmembrane protein 87B
chr1_-_229434086 0.53 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
ACTA1
actin alpha 1, skeletal muscle
chr20_-_52105644 0.53 ENST00000371523.8
ZFP64
ZFP64 zinc finger protein
chrX_+_47078380 0.51 ENST00000352078.8
RGN
regucalcin
chr14_-_65102468 0.51 ENST00000555932.5
ENST00000284165.10
ENST00000358402.8
ENST00000246163.2
ENST00000358664.9
ENST00000556979.5
ENST00000555667.5
ENST00000557746.5
ENST00000556443.5
ENST00000618858.4
ENST00000557277.5
ENST00000556892.5
MAX
MYC associated factor X
chr13_+_112968496 0.50 ENST00000397030.5
MCF2L
MCF.2 cell line derived transforming sequence like
chr11_+_125592826 0.50 ENST00000529196.5
ENST00000392708.9
ENST00000649491.1
ENST00000531491.5
STT3A
STT3 oligosaccharyltransferase complex catalytic subunit A
chr1_-_202161575 0.50 ENST00000309017.7
ENST00000477554.5
ENST00000492451.1
PTPN7
protein tyrosine phosphatase non-receptor type 7
chrX_+_154886355 0.49 ENST00000610495.2
F8A1
coagulation factor VIII associated 1
chrX_-_155458620 0.48 ENST00000622749.2
F8A3
coagulation factor VIII associated 3
chr19_+_46298382 0.48 ENST00000244303.10
ENST00000533145.5
ENST00000472815.5
HIF3A
hypoxia inducible factor 3 subunit alpha
chr9_-_25678375 0.47 ENST00000358022.6
TUSC1
tumor suppressor candidate 1
chr19_+_1491140 0.47 ENST00000233596.8
ENST00000395479.10
REEP6
receptor accessory protein 6
chrX_+_155382095 0.47 ENST00000369505.5
F8A2
coagulation factor VIII associated 2
chr7_-_5423826 0.47 ENST00000430969.6
TNRC18
trinucleotide repeat containing 18
chr1_-_242449478 0.46 ENST00000427495.5
PLD5
phospholipase D family member 5
chr1_-_219928551 0.46 ENST00000366926.4
SLC30A10
solute carrier family 30 member 10
chr1_+_240014319 0.46 ENST00000447095.5
FMN2
formin 2
chr11_-_67508091 0.46 ENST00000531506.1
CDK2AP2
cyclin dependent kinase 2 associated protein 2
chr17_+_59565598 0.46 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DHX40
DEAH-box helicase 40
chr2_-_172102893 0.45 ENST00000234198.9
ENST00000466293.2
DLX2
distal-less homeobox 2
chr1_-_243255320 0.45 ENST00000366544.5
ENST00000366543.5
CEP170
centrosomal protein 170
chr9_+_99821876 0.45 ENST00000395097.7
NR4A3
nuclear receptor subfamily 4 group A member 3
chr14_-_75980993 0.45 ENST00000556285.1
TGFB3
transforming growth factor beta 3
chr19_-_35757009 0.45 ENST00000587965.1
ENST00000004982.6
HSPB6
heat shock protein family B (small) member 6
chr5_+_141475928 0.45 ENST00000611950.1
ENST00000308177.5
ENST00000617641.4
ENST00000621008.1
ENST00000617222.4
PCDHGC3
protocadherin gamma subfamily C, 3
chr2_+_68774782 0.44 ENST00000409030.7
ENST00000409220.5
ARHGAP25
Rho GTPase activating protein 25
chr3_-_52452828 0.44 ENST00000496590.1
TNNC1
troponin C1, slow skeletal and cardiac type
chr19_-_7699466 0.44 ENST00000360067.8
FCER2
Fc fragment of IgE receptor II
chr2_+_218323148 0.43 ENST00000258362.7
PNKD
PNKD metallo-beta-lactamase domain containing
chr4_+_54100161 0.43 ENST00000326902.7
ENST00000503800.1
GSX2
GS homeobox 2
chr9_-_16705062 0.43 ENST00000471301.3
BNC2
basonuclin 2
chr8_-_10655137 0.42 ENST00000382483.4
RP1L1
RP1 like 1
chr16_-_67481131 0.42 ENST00000290949.8
ATP6V0D1
ATPase H+ transporting V0 subunit d1
chr12_-_52367478 0.42 ENST00000257901.7
KRT85
keratin 85
chr12_+_100473708 0.41 ENST00000548884.5
ENST00000392986.8
NR1H4
nuclear receptor subfamily 1 group H member 4
chr17_+_7558465 0.41 ENST00000349228.8
TNFSF13
TNF superfamily member 13
chr1_-_235328147 0.41 ENST00000264183.9
ENST00000418304.1
ENST00000349213.7
ARID4B
AT-rich interaction domain 4B
chr8_-_22156741 0.41 ENST00000424267.6
LGI3
leucine rich repeat LGI family member 3
chr11_+_68008542 0.41 ENST00000614849.4
ALDH3B1
aldehyde dehydrogenase 3 family member B1
chrX_+_145817798 0.41 ENST00000335565.6
SLITRK2
SLIT and NTRK like family member 2
chr2_+_227472132 0.40 ENST00000409979.6
ENST00000310078.13
AGFG1
ArfGAP with FG repeats 1
chr6_-_17706748 0.40 ENST00000613258.4
ENST00000537253.5
NUP153
nucleoporin 153

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.4 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
2.6 7.9 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
2.6 10.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.7 5.0 GO:0046521 sphingoid catabolic process(GO:0046521)
1.1 3.3 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
1.0 3.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.9 3.4 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.8 2.5 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.8 3.2 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.7 3.0 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.7 4.9 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.6 5.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 2.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.5 3.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.5 5.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.5 1.8 GO:1903633 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.5 4.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.4 1.8 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.4 1.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.4 1.5 GO:0003095 pressure natriuresis(GO:0003095)
0.4 1.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.4 2.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.4 1.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.3 3.4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.3 2.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 2.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.3 4.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.3 1.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.3 1.0 GO:0038185 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.3 0.8 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.2 0.7 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.9 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.2 2.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 0.5 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.2 0.9 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 2.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.2 0.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 0.5 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.1 2.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.7 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.1 2.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.6 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.4 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 1.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 1.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.7 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.4 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 1.3 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.1 0.6 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:0051182 coenzyme transport(GO:0051182)
0.1 3.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.7 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 1.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.9 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.5 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 1.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 1.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.2 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.1 2.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.3 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.2 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.4 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 9.7 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 1.0 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.7 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 17.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.7 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0072180 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.7 GO:0007614 short-term memory(GO:0007614)
0.0 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:2000393 negative regulation of ruffle assembly(GO:1900028) negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.6 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0035787 cell migration involved in kidney development(GO:0035787)
0.0 0.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.6 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704) progesterone metabolic process(GO:0042448)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.3 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.4 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.0 GO:0060694 regulation of cholesterol transporter activity(GO:0060694)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.3 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 2.4 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.4 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 3.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891) sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.2 3.5 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.8 0.8 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.3 2.7 GO:0097451 glial limiting end-foot(GO:0097451)
0.3 3.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 1.2 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.2 3.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 0.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 1.7 GO:0005638 lamin filament(GO:0005638)
0.1 1.1 GO:0031415 NatA complex(GO:0031415)
0.1 9.9 GO:0015030 Cajal body(GO:0015030)
0.1 1.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 4.6 GO:0030673 axolemma(GO:0030673)
0.1 2.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 9.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 4.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 5.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 4.9 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 2.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 2.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 2.9 GO:0043197 dendritic spine(GO:0043197)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0008859 exoribonuclease II activity(GO:0008859)
2.0 7.9 GO:0035939 microsatellite binding(GO:0035939)
1.8 12.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.5 5.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 2.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.8 2.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.8 3.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.8 3.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.7 3.0 GO:0035501 MH1 domain binding(GO:0035501)
0.7 5.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 1.8 GO:0004341 gluconolactonase activity(GO:0004341)
0.4 1.8 GO:0050436 microfibril binding(GO:0050436)
0.4 1.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.3 3.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 4.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.2 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.3 2.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 1.0 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 2.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.7 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
0.2 1.4 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.2 1.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 2.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 9.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 0.5 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 3.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.4 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 1.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.3 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 3.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 2.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 0.3 GO:0015265 urea channel activity(GO:0015265)
0.1 4.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.6 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 2.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 7.6 GO:0005518 collagen binding(GO:0005518)
0.1 28.4 GO:0005525 GTP binding(GO:0005525)
0.1 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 5.7 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 3.6 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.6 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 10.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 8.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 2.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 5.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 8.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 3.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.1 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 12.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 5.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 8.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 10.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 3.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 7.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 3.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 2.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 4.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG