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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TLX2

Z-value: 1.01

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Transcription factors associated with TLX2

Gene Symbol Gene ID Gene Info
ENSG00000115297.11 TLX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TLX2hg38_v1_chr2_+_74513441_74513559,
hg38_v1_chr2_+_74514442_74514494
-0.203.3e-01Click!

Activity profile of TLX2 motif

Sorted Z-values of TLX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_57372465 6.62 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr16_+_57372481 6.61 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr1_-_169734064 6.08 ENST00000333360.12
selectin E
chr6_-_31582415 4.21 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr5_+_132073782 4.15 ENST00000296871.4
colony stimulating factor 2
chr6_-_142945028 4.00 ENST00000012134.7
HIVEP zinc finger 2
chr6_-_142945160 3.96 ENST00000367603.8
HIVEP zinc finger 2
chr19_+_676385 2.63 ENST00000166139.9
follistatin like 3
chr3_-_71305986 2.49 ENST00000647614.1
forkhead box P1
chr16_-_11587162 2.45 ENST00000570904.5
ENST00000574701.5
lipopolysaccharide induced TNF factor
chr2_-_224947030 1.92 ENST00000409592.7
dedicator of cytokinesis 10
chr12_-_89524734 1.78 ENST00000529983.3
polypeptide N-acetylgalactosaminyltransferase 4
chr14_+_103123452 1.75 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr16_-_11586903 1.65 ENST00000571459.5
ENST00000570798.5
ENST00000622633.5
ENST00000572255.5
ENST00000574763.5
ENST00000574703.5
ENST00000571277.1
lipopolysaccharide induced TNF factor
chr21_+_42219123 1.63 ENST00000398449.8
ATP binding cassette subfamily G member 1
chr21_+_42219111 1.60 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr16_-_11586941 1.48 ENST00000571976.1
ENST00000413364.6
lipopolysaccharide induced TNF factor
chr3_-_108090971 1.43 ENST00000355354.13
ENST00000361309.6
CD47 molecule
chr1_-_120100688 1.42 ENST00000652264.1
notch receptor 2
chr2_+_102311502 1.34 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr5_-_16916400 1.34 ENST00000513882.5
myosin X
chr21_-_37267511 1.24 ENST00000398998.1
VPS26 endosomal protein sorting factor C
chr15_-_50119215 1.18 ENST00000284509.11
ENST00000674213.1
ATPase phospholipid transporting 8B4 (putative)
chr1_+_169106681 1.17 ENST00000367815.9
ATPase Na+/K+ transporting subunit beta 1
chr2_+_111120906 1.12 ENST00000337565.9
ENST00000357757.6
ENST00000308659.12
ENST00000393256.8
ENST00000610735.4
ENST00000615946.4
ENST00000619294.4
ENST00000620862.4
ENST00000621302.4
ENST00000622509.4
ENST00000622612.4
BCL2 like 11
chr3_-_183162726 1.10 ENST00000265598.8
lysosomal associated membrane protein 3
chr12_-_42589592 1.10 ENST00000552108.6
ENST00000547113.1
ENST00000640646.1
prickle planar cell polarity protein 1
chr12_-_57129001 1.09 ENST00000556155.5
signal transducer and activator of transcription 6
chr16_+_56336805 1.03 ENST00000564727.2
G protein subunit alpha o1
chr2_-_203535253 1.02 ENST00000457812.5
ENST00000319170.10
ENST00000630330.2
ENST00000308091.8
ENST00000453034.5
ENST00000420371.2
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr8_-_90645512 0.98 ENST00000422900.1
transmembrane protein 64
chr6_+_106098933 0.96 ENST00000369089.3
PR/SET domain 1
chr2_+_218568865 0.96 ENST00000295701.9
CCR4-NOT transcription complex subunit 9
chr8_-_104589241 0.94 ENST00000276654.10
LDL receptor related protein 12
chr5_+_126423363 0.93 ENST00000285689.8
GRAM domain containing 2B
chr17_+_68512878 0.93 ENST00000585981.5
ENST00000589480.5
ENST00000585815.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr10_-_58267868 0.93 ENST00000373935.4
inositol polyphosphate multikinase
chr2_+_149330506 0.92 ENST00000334166.9
LY6/PLAUR domain containing 6
chr1_-_116570974 0.89 ENST00000369489.10
ENST00000457047.6
ENST00000369487.3
CD58 molecule
chr8_-_104588998 0.88 ENST00000424843.6
LDL receptor related protein 12
chr7_+_45157784 0.85 ENST00000242249.8
ENST00000496212.5
ENST00000481345.1
receptor activity modifying protein 3
chr7_+_155298561 0.81 ENST00000476756.1
insulin induced gene 1
chr3_+_4979428 0.78 ENST00000256495.4
basic helix-loop-helix family member e40
chr1_-_44843240 0.77 ENST00000372192.4
patched 2
chr6_+_158017048 0.77 ENST00000638626.1
synaptojanin 2
chr10_-_119872754 0.76 ENST00000360003.7
minichromosome maintenance complex binding protein
chr10_-_119872832 0.76 ENST00000369077.4
minichromosome maintenance complex binding protein
chr2_+_218568558 0.71 ENST00000627282.2
ENST00000542068.5
CCR4-NOT transcription complex subunit 9
chr2_-_46941710 0.70 ENST00000409207.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr11_+_35139162 0.70 ENST00000415148.6
ENST00000263398.11
ENST00000428726.8
ENST00000526669.6
ENST00000433892.6
ENST00000525211.6
ENST00000278386.10
ENST00000434472.6
ENST00000352818.8
ENST00000442151.6
CD44 molecule (Indian blood group)
chr9_-_127715602 0.70 ENST00000456267.5
ENST00000414832.2
peptidyl-tRNA hydrolase 1 homolog
chr19_+_35745590 0.70 ENST00000591949.1
presenilin enhancer, gamma-secretase subunit
chr18_+_58195390 0.70 ENST00000456173.6
ENST00000676226.1
ENST00000675865.1
NEDD4 like E3 ubiquitin protein ligase
chr19_-_12722547 0.69 ENST00000592287.5
transportin 2
chr19_+_35745613 0.69 ENST00000222266.2
ENST00000587708.7
presenilin enhancer, gamma-secretase subunit
chr6_-_43528867 0.68 ENST00000455285.2
exportin 5
chr1_-_161309961 0.68 ENST00000533357.5
ENST00000672602.2
ENST00000526189.3
myelin protein zero
chr20_+_2814981 0.68 ENST00000603872.2
ENST00000380589.4
chromosome 20 open reading frame 141
chr11_-_57322197 0.68 ENST00000532437.1
tankyrase 1 binding protein 1
chr8_+_119416427 0.67 ENST00000259526.4
cellular communication network factor 3
chr5_+_131264043 0.67 ENST00000505065.2
ENST00000503291.5
ENST00000360515.7
CDC42 small effector 2
chr1_+_154257071 0.66 ENST00000428595.1
ubiquitin associated protein 2 like
chr3_-_71306012 0.66 ENST00000649431.1
ENST00000610810.5
forkhead box P1
chr20_+_46118300 0.63 ENST00000372285.8
ENST00000372276.7
CD40 molecule
chr12_+_116910935 0.61 ENST00000652555.1
ENST00000455858.2
F-box and WD repeat domain containing 8
chr1_+_15847698 0.61 ENST00000375759.8
spen family transcriptional repressor
chr10_-_43396831 0.60 ENST00000443950.6
heterogeneous nuclear ribonucleoprotein F
chr20_+_46118277 0.60 ENST00000620709.4
CD40 molecule
chr4_+_168631597 0.60 ENST00000504519.5
ENST00000512127.5
palladin, cytoskeletal associated protein
chr5_+_131264008 0.59 ENST00000395246.5
CDC42 small effector 2
chr12_-_76559569 0.59 ENST00000551927.5
oxysterol binding protein like 8
chr10_-_49762276 0.58 ENST00000374103.9
oxoglutarate dehydrogenase L
chr21_-_15064934 0.57 ENST00000400199.5
ENST00000400202.5
ENST00000318948.7
nuclear receptor interacting protein 1
chr2_-_69387130 0.57 ENST00000674438.1
glutamine--fructose-6-phosphate transaminase 1
chr16_+_56336767 0.56 ENST00000640469.1
G protein subunit alpha o1
chr10_-_49762335 0.55 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr2_+_218568809 0.54 ENST00000273064.11
CCR4-NOT transcription complex subunit 9
chr2_-_175005357 0.54 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr12_-_213338 0.54 ENST00000424061.6
solute carrier family 6 member 12
chr19_+_43576800 0.52 ENST00000612042.4
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr5_+_178113519 0.51 ENST00000274605.6
NEDD4 binding protein 3
chr5_+_134648772 0.50 ENST00000398844.7
ENST00000322887.8
SEC24 homolog A, COPII coat complex component
chr19_+_46601237 0.50 ENST00000597743.5
calmodulin 3
chr15_-_38564635 0.50 ENST00000450598.6
ENST00000559830.5
ENST00000558164.5
ENST00000539159.5
ENST00000310803.10
RAS guanyl releasing protein 1
chr7_+_112423137 0.49 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr18_-_26091175 0.49 ENST00000579061.5
ENST00000542420.6
SS18 subunit of BAF chromatin remodeling complex
chr18_+_31498168 0.49 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr14_-_21269392 0.48 ENST00000554891.5
ENST00000555883.5
ENST00000553753.5
ENST00000555914.5
ENST00000557336.1
ENST00000555215.5
ENST00000556628.5
ENST00000555137.5
ENST00000556226.5
ENST00000555309.5
ENST00000556142.5
ENST00000554969.5
ENST00000554455.5
ENST00000556513.5
ENST00000557201.5
ENST00000420743.6
ENST00000557768.1
ENST00000553300.6
ENST00000554383.5
ENST00000554539.5
heterogeneous nuclear ribonucleoprotein C
chr12_-_47725558 0.48 ENST00000229003.7
endonuclease, poly(U) specific
chr12_-_76559733 0.48 ENST00000547540.5
oxysterol binding protein like 8
chr17_+_44847874 0.48 ENST00000253410.3
HIG1 hypoxia inducible domain family member 1B
chr6_-_138107412 0.48 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr12_-_76559672 0.48 ENST00000549570.5
oxysterol binding protein like 8
chr9_+_136952896 0.48 ENST00000371632.7
lipocalin 12
chr3_-_71581829 0.48 ENST00000649610.1
forkhead box P1
chr2_-_196592671 0.48 ENST00000260983.8
ENST00000644030.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr15_+_89088417 0.48 ENST00000569550.5
ENST00000565066.5
ENST00000565973.5
ENST00000352732.10
abhydrolase domain containing 2, acylglycerol lipase
chr7_+_101085464 0.47 ENST00000306085.11
ENST00000412507.1
tripartite motif containing 56
chr14_-_21269451 0.47 ENST00000336053.10
heterogeneous nuclear ribonucleoprotein C
chr8_+_31640358 0.47 ENST00000523534.5
neuregulin 1
chr3_+_46370854 0.46 ENST00000292303.4
C-C motif chemokine receptor 5
chr2_+_10044175 0.46 ENST00000440320.5
ENST00000535335.1
Kruppel like factor 11
chr12_-_51346679 0.46 ENST00000293636.2
chymotrypsin like elastase 1
chr12_-_47725483 0.46 ENST00000422538.8
endonuclease, poly(U) specific
chr2_-_287320 0.45 ENST00000401503.5
ALK and LTK ligand 2
chr5_+_134115563 0.44 ENST00000517851.5
ENST00000521639.5
ENST00000522375.5
ENST00000378560.8
ENST00000520958.5
ENST00000518915.5
ENST00000395023.5
transcription factor 7
chr1_+_119507203 0.43 ENST00000369413.8
ENST00000528909.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr8_+_41578176 0.42 ENST00000396987.7
ENST00000519853.5
glycerol-3-phosphate acyltransferase 4
chr19_+_15049469 0.42 ENST00000427043.4
caspase 14
chr1_+_23959797 0.42 ENST00000374468.1
ENST00000334351.8
proline rich nuclear receptor coactivator 2
chr7_+_31687208 0.42 ENST00000409146.3
ENST00000342032.8
protein phosphatase 1 regulatory subunit 17
chr3_+_122077776 0.42 ENST00000264468.9
CD86 molecule
chr5_-_147782518 0.41 ENST00000507386.5
janus kinase and microtubule interacting protein 2
chr1_+_50109817 0.41 ENST00000652353.1
ENST00000371821.6
ENST00000652274.1
ELAV like RNA binding protein 4
chr11_+_57667747 0.41 ENST00000527985.5
zinc finger DHHC-type palmitoyltransferase 5
chr20_-_46406559 0.40 ENST00000372176.5
engulfment and cell motility 2
chr18_-_26090584 0.40 ENST00000415083.7
SS18 subunit of BAF chromatin remodeling complex
chr20_-_46406582 0.40 ENST00000450812.5
ENST00000290246.11
ENST00000396391.5
engulfment and cell motility 2
chr6_+_110982028 0.40 ENST00000441448.7
ribosome production factor 2 homolog
chr6_+_116370938 0.40 ENST00000644252.3
ENST00000646710.1
ENST00000359564.3
dermatan sulfate epimerase
chr9_-_72364504 0.40 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chr12_-_70788914 0.39 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr1_-_153544997 0.38 ENST00000368715.5
S100 calcium binding protein A4
chr17_+_82237134 0.38 ENST00000583025.1
solute carrier family 16 member 3
chr5_-_150700910 0.38 ENST00000521464.1
ENST00000518917.5
ENST00000447771.6
ENST00000199814.9
RNA binding motif protein 22
chr7_-_44141285 0.38 ENST00000458240.5
ENST00000223364.7
myosin light chain 7
chr12_+_112791933 0.38 ENST00000551052.5
ENST00000415485.7
rabphilin 3A
chr1_+_50109620 0.38 ENST00000371819.1
ELAV like RNA binding protein 4
chr6_-_33314055 0.38 ENST00000434618.7
TAP binding protein
chr8_+_62248933 0.37 ENST00000523211.5
ENST00000524201.1
sodium/potassium transporting ATPase interacting 3
chr3_+_38496329 0.37 ENST00000287675.10
ENST00000630638.1
ENST00000422077.6
exo/endonuclease G
chr3_-_112975018 0.37 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr3_-_71581540 0.37 ENST00000650068.1
forkhead box P1
chr2_+_169066994 0.37 ENST00000357546.6
ENST00000432060.6
dehydrogenase/reductase 9
chr8_-_81112055 0.37 ENST00000220597.4
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr4_+_39044995 0.36 ENST00000261425.7
ENST00000508137.6
kelch like family member 5
chr11_-_107858777 0.36 ENST00000525815.6
solute carrier family 35 member F2
chr17_-_7393404 0.36 ENST00000575434.4
phospholipid scramblase 3
chr7_+_54542393 0.35 ENST00000404951.5
V-set and transmembrane domain containing 2A
chr3_+_122055355 0.35 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr12_+_50400809 0.35 ENST00000293618.12
ENST00000429001.7
ENST00000398473.7
ENST00000548174.5
ENST00000548697.5
ENST00000548993.5
ENST00000614335.4
ENST00000522085.5
ENST00000615080.4
ENST00000518444.5
ENST00000551886.5
ENST00000523389.5
ENST00000518561.5
ENST00000347328.9
ENST00000550260.1
La ribonucleoprotein 4
chr11_+_111245725 0.34 ENST00000280325.7
chromosome 11 open reading frame 53
chr20_-_62926469 0.34 ENST00000354665.8
ENST00000370368.5
ENST00000395340.5
ENST00000395343.6
death inducer-obliterator 1
chr10_+_35126923 0.34 ENST00000374726.7
cAMP responsive element modulator
chr6_+_75749272 0.34 ENST00000653423.1
myosin VI
chr3_+_119173515 0.34 ENST00000497685.5
uroplakin 1B
chr16_-_70801131 0.33 ENST00000261776.10
VAC14 component of PIKFYVE complex
chr6_+_26440472 0.33 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr11_-_83682414 0.33 ENST00000404783.7
discs large MAGUK scaffold protein 2
chr14_-_56805648 0.33 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chr7_+_75915148 0.33 ENST00000461988.6
ENST00000421059.1
ENST00000394893.5
ENST00000412521.5
ENST00000414186.5
cytochrome p450 oxidoreductase
chr17_+_44847905 0.33 ENST00000587021.1
HIG1 hypoxia inducible domain family member 1B
chr1_-_159925496 0.33 ENST00000368097.9
transgelin 2
chr8_+_90940517 0.33 ENST00000521366.1
N-terminal EF-hand calcium binding protein 1
chr2_+_10043524 0.33 ENST00000305883.6
Kruppel like factor 11
chr11_-_3797490 0.33 ENST00000397004.8
ENST00000397007.8
ENST00000532475.1
ENST00000324932.12
nucleoporin 98 and 96 precursor
chr19_+_38930916 0.33 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
mitochondrial ribosomal protein S12
chr3_+_122077850 0.32 ENST00000482356.5
ENST00000393627.6
CD86 molecule
chr19_+_46601296 0.32 ENST00000598871.5
ENST00000291295.14
ENST00000594523.5
calmodulin 3
chr10_+_110005804 0.32 ENST00000360162.7
adducin 3
chr5_-_147782681 0.32 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
janus kinase and microtubule interacting protein 2
chr10_+_122271292 0.32 ENST00000260723.6
BTB domain containing 16
chr7_+_121873152 0.32 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
protein tyrosine phosphatase receptor type Z1
chr20_-_1393074 0.32 ENST00000614856.2
ENST00000678408.1
ENST00000618612.5
ENST00000439640.5
ENST00000381719.8
ENST00000677533.1
FKBP prolyl isomerase 1A
chr7_-_131556602 0.32 ENST00000322985.9
ENST00000378555.8
podocalyxin like
chr1_+_207454230 0.32 ENST00000367058.7
ENST00000367059.3
ENST00000367057.8
complement C3d receptor 2
chr18_+_57435366 0.32 ENST00000491143.3
one cut homeobox 2
chr1_+_205504592 0.31 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chr14_-_24242320 0.31 ENST00000557921.2
TERF1 interacting nuclear factor 2
chr21_-_37267300 0.31 ENST00000309117.11
ENST00000476950.5
ENST00000399001.5
VPS26 endosomal protein sorting factor C
chr5_+_96662046 0.31 ENST00000338252.7
ENST00000508830.5
calpastatin
chr6_+_83853576 0.30 ENST00000369687.2
ripply transcriptional repressor 2
chr1_-_74198132 0.30 ENST00000370911.7
ENST00000370909.6
ENST00000354431.9
leucine rich repeats and IQ motif containing 3
chr20_-_1393045 0.30 ENST00000400137.9
ENST00000381715.4
FKBP prolyl isomerase 1A
chr12_-_50283472 0.30 ENST00000551691.5
ENST00000394943.7
ENST00000341247.8
LIM domain and actin binding 1
chr7_+_121873089 0.30 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr10_+_35127295 0.30 ENST00000489321.5
ENST00000427847.6
ENST00000374728.7
ENST00000345491.7
ENST00000487132.5
cAMP responsive element modulator
chr17_-_19386785 0.30 ENST00000497081.6
microfibril associated protein 4
chr19_-_12722350 0.30 ENST00000356861.9
transportin 2
chr11_-_117824734 0.30 ENST00000292079.7
FXYD domain containing ion transport regulator 2
chr10_-_72215903 0.30 ENST00000526751.5
ENST00000672774.1
ENST00000394919.5
ENST00000394915.7
activating signal cointegrator 1 complex subunit 1
chr19_-_51646800 0.29 ENST00000599649.5
ENST00000429354.3
ENST00000360844.6
sialic acid binding Ig like lectin 5
sialic acid binding Ig like lectin 14
chr9_+_113463697 0.29 ENST00000317613.10
regulator of G protein signaling 3
chr5_+_149271848 0.29 ENST00000296721.9
actin filament associated protein 1 like 1
chr11_+_13962676 0.29 ENST00000576479.4
spondin 1
chr2_-_223837484 0.29 ENST00000446015.6
ENST00000409375.1
adaptor related protein complex 1 subunit sigma 3
chr7_+_54542362 0.28 ENST00000402613.4
V-set and transmembrane domain containing 2A
chr11_+_64291285 0.28 ENST00000422670.7
ENST00000538767.1
potassium two pore domain channel subfamily K member 4
chr12_+_57128656 0.28 ENST00000338962.8
LDL receptor related protein 1
chr20_-_63254429 0.28 ENST00000370316.8
sodium/potassium transporting ATPase interacting 4
chr14_+_93927259 0.28 ENST00000556222.1
ENST00000554404.1
family with sequence similarity 181 member A
chr1_-_183653307 0.28 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr7_-_22500152 0.28 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr1_-_1658988 0.28 ENST00000341832.11
ENST00000407249.7
ENST00000340677.9
ENST00000626918.2
ENST00000629289.2
ENST00000629312.2
cyclin dependent kinase 11B
chr16_+_66366675 0.28 ENST00000341529.8
ENST00000649567.1
cadherin 5
chr1_-_153057504 0.27 ENST00000392653.3
small proline rich protein 2A
chr22_+_50486784 0.27 ENST00000395733.7
myo-inositol oxygenase
chr20_+_45221362 0.27 ENST00000372769.4
semenogelin 2
chr10_+_35127162 0.27 ENST00000354759.7
cAMP responsive element modulator
chr10_-_72216267 0.27 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
activating signal cointegrator 1 complex subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
1.1 3.2 GO:0009720 detection of hormone stimulus(GO:0009720)
0.8 4.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.5 4.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.4 2.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 1.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.4 1.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.4 1.1 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 1.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.3 1.2 GO:0033590 response to cobalamin(GO:0033590)
0.3 1.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 0.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 6.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 4.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.7 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.2 1.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 1.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 3.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.5 GO:0007518 myoblast fate determination(GO:0007518)
0.2 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.2 0.6 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.2 0.5 GO:0060309 elastin catabolic process(GO:0060309)
0.1 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 2.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.6 GO:0070378 positive regulation of ERK5 cascade(GO:0070378)
0.1 5.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.4 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.1 1.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 1.8 GO:0051601 exocyst localization(GO:0051601)
0.1 0.2 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.1 0.3 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.4 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.3 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.1 0.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.5 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.5 GO:0003164 His-Purkinje system development(GO:0003164)
0.1 0.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.4 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.8 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 1.4 GO:0008228 opsonization(GO:0008228)
0.1 0.4 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 1.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 1.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.5 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.2 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 0.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.3 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.9 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.0 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0044805 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) response to fluoride(GO:1902617)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 1.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.6 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.6 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.8 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0090131 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.5 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.1 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.1 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 1.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 1.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.6 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.0 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-4 production(GO:0032713)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.4 1.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 0.7 GO:0042565 RNA nuclear export complex(GO:0042565)
0.2 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 2.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 1.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.2 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.6 GO:0072534 perineuronal net(GO:0072534)
0.1 1.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.8 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.4 GO:0032433 filopodium tip(GO:0032433)
0.1 8.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.8 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 3.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 19.0 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.7 GO:0005771 multivesicular body(GO:0005771)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 2.3 GO:0043197 dendritic spine(GO:0043197)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0089701 U2AF(GO:0089701)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.5 6.0 GO:0033691 sialic acid binding(GO:0033691)
0.5 1.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 12.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 0.7 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.2 0.9 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 0.7 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 1.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 3.2 GO:0048185 activin binding(GO:0048185)
0.2 0.8 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 1.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.6 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.6 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.1 1.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.1 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.3 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 5.6 GO:0050699 WW domain binding(GO:0050699)
0.1 1.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 4.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.8 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.3 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 1.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 4.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.0 1.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.0 1.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0043125 ErbB-2 class receptor binding(GO:0005176) ErbB-3 class receptor binding(GO:0043125)
0.0 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 3.3 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 1.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 14.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 5.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 2.8 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 3.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 4.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 3.7 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)