Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for TP53

Z-value: 0.58

Motif logo

Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
ENSG00000141510.18 TP53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg38_v1_chr17_-_7687427_76875380.262.1e-01Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr5_-_132490750 1.13 ENST00000437654.6
ENST00000245414.9
ENST00000680139.1
ENST00000680352.1
ENST00000679440.1
ENST00000680903.1
interferon regulatory factor 1
chr6_+_36676489 1.05 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr6_+_36676455 1.05 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr16_+_57372481 0.86 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr16_+_57372465 0.85 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr12_+_22625357 0.71 ENST00000545979.2
ethanolamine kinase 1
chr8_-_23164020 0.64 ENST00000312584.4
TNF receptor superfamily member 10d
chr18_+_59899988 0.58 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr19_+_507487 0.57 ENST00000359315.6
tubulin polyglutamylase complex subunit 1
chr8_-_23069012 0.56 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr6_-_30742203 0.53 ENST00000416018.5
ENST00000445853.5
ENST00000413165.5
ENST00000418160.5
flotillin 1
chr5_+_10564064 0.49 ENST00000296657.7
ankyrin repeat domain 33B
chr10_+_129467178 0.48 ENST00000306010.8
ENST00000651593.1
O-6-methylguanine-DNA methyltransferase
chr19_-_47232649 0.47 ENST00000449228.5
ENST00000300880.11
ENST00000341983.8
BCL2 binding component 3
chr2_-_234497035 0.46 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr16_-_4614876 0.46 ENST00000591401.5
ENST00000283474.12
ENST00000591897.5
UBA like domain containing 1
chr5_+_122311740 0.44 ENST00000506272.5
ENST00000508681.5
ENST00000509154.6
synuclein alpha interacting protein
chr8_-_10730498 0.44 ENST00000304501.2
SRY-box transcription factor 7
chr8_+_23102913 0.41 ENST00000356864.4
TNF receptor superfamily member 10c
chr16_+_57619942 0.41 ENST00000568908.5
ENST00000568909.5
ENST00000566778.5
ENST00000561988.5
adhesion G protein-coupled receptor G1
chr5_+_122312229 0.41 ENST00000261368.13
synuclein alpha interacting protein
chr5_+_122312164 0.40 ENST00000514497.6
ENST00000261367.11
synuclein alpha interacting protein
chr16_+_57620077 0.40 ENST00000567835.5
ENST00000569372.5
ENST00000563548.5
ENST00000562003.5
adhesion G protein-coupled receptor G1
chr15_+_88621290 0.37 ENST00000332810.4
ENST00000559528.1
apoptosis enhancing nuclease
chr7_+_154305256 0.37 ENST00000619756.4
dipeptidyl peptidase like 6
chr1_-_17011891 0.37 ENST00000341676.9
ENST00000326735.13
ENST00000452699.5
ATPase cation transporting 13A2
chr17_+_78214186 0.35 ENST00000301633.8
ENST00000350051.8
ENST00000374948.6
ENST00000590449.1
baculoviral IAP repeat containing 5
chr7_+_48088596 0.34 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr20_+_35172046 0.34 ENST00000216968.5
protein C receptor
chr9_+_136952256 0.34 ENST00000371633.8
lipocalin 12
chr20_-_5119945 0.34 ENST00000379143.10
proliferating cell nuclear antigen
chr8_+_42338454 0.34 ENST00000532157.5
ENST00000520008.5
DNA polymerase beta
chrX_+_152917830 0.33 ENST00000318529.12
zinc finger protein 185 with LIM domain
chr11_-_44950839 0.33 ENST00000395648.7
ENST00000531928.6
tumor protein p53 inducible protein 11
chr9_+_136952896 0.32 ENST00000371632.7
lipocalin 12
chr3_+_32106612 0.31 ENST00000282541.10
ENST00000425459.5
ENST00000431009.1
glycerol-3-phosphate dehydrogenase 1 like
chr17_+_76376581 0.30 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr1_-_54406385 0.30 ENST00000610401.5
single stranded DNA binding protein 3
chr2_-_288056 0.30 ENST00000403610.9
ALK and LTK ligand 2
chr20_+_44355692 0.29 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr12_-_6342020 0.29 ENST00000540022.5
ENST00000536194.1
TNF receptor superfamily member 1A
chr9_-_133121148 0.28 ENST00000372047.7
ral guanine nucleotide dissociation stimulator
chr4_-_10116324 0.27 ENST00000508079.1
WD repeat domain 1
chr1_-_156741067 0.27 ENST00000361531.6
ENST00000412846.5
mitochondrial ribosomal protein L24
chr19_+_35371290 0.27 ENST00000597214.1
G protein-coupled receptor 42
chr11_-_73598183 0.26 ENST00000064778.8
family with sequence similarity 168 member A
chr17_+_78214286 0.26 ENST00000592734.5
ENST00000587746.5
baculoviral IAP repeat containing 5
chr1_+_156082563 0.26 ENST00000368301.6
lamin A/C
chr10_+_88990736 0.25 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor
chr19_+_48954850 0.25 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BCL2 associated X, apoptosis regulator
chr1_-_156741124 0.25 ENST00000368211.8
mitochondrial ribosomal protein L24
chr11_+_65111845 0.25 ENST00000526809.5
ENST00000524986.5
ENST00000534371.5
ENST00000279263.14
ENST00000525385.5
ENST00000345348.9
ENST00000531321.5
ENST00000529414.5
ENST00000526085.5
ENST00000530750.5
transmembrane 7 superfamily member 2
chr19_-_42242526 0.25 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr6_-_30744537 0.25 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr7_+_101127095 0.25 ENST00000223095.5
serpin family E member 1
chr9_-_133121228 0.25 ENST00000372050.8
ral guanine nucleotide dissociation stimulator
chr11_-_73598067 0.23 ENST00000450446.6
ENST00000356467.5
family with sequence similarity 168 member A
chr9_-_135961310 0.23 ENST00000371756.4
UBA domain containing 1
chr1_-_53945567 0.22 ENST00000371378.6
heat shock protein family B (small) member 11
chr10_-_125158704 0.22 ENST00000531469.5
C-terminal binding protein 2
chr11_-_75306688 0.22 ENST00000532525.1
arrestin beta 1
chr1_-_53945584 0.22 ENST00000371377.3
heat shock protein family B (small) member 11
chr17_+_20579724 0.22 ENST00000661883.1
ENST00000399044.1
CMT1A duplicated region transcript 15 like 2
chr11_-_73982830 0.22 ENST00000536983.5
ENST00000663595.2
ENST00000310473.9
uncoupling protein 2
chr20_-_23826721 0.21 ENST00000304725.3
cystatin SA
chr12_-_54648356 0.20 ENST00000293371.11
ENST00000456047.2
dermcidin
chr16_+_77722502 0.20 ENST00000564085.5
ENST00000268533.9
ENST00000568787.5
ENST00000437314.3
ENST00000563839.1
nudix hydrolase 7
chr16_+_2029636 0.19 ENST00000561844.5
SLC9A3 regulator 2
chr22_+_19718390 0.19 ENST00000383045.7
ENST00000438754.6
septin 5
chr2_-_25982471 0.19 ENST00000264712.8
kinesin family member 3C
chr16_-_67966793 0.18 ENST00000541864.6
solute carrier family 12 member 4
chr19_-_8698705 0.18 ENST00000612068.1
actin like 9
chr1_-_54053394 0.18 ENST00000452421.5
ENST00000420738.5
ENST00000440019.5
transmembrane protein 59
chr16_+_77722473 0.18 ENST00000613075.4
nudix hydrolase 7
chr3_-_42875871 0.18 ENST00000316161.6
ENST00000437102.1
cytochrome P450 family 8 subfamily B member 1
chr14_+_50533026 0.17 ENST00000441560.6
atlastin GTPase 1
chr20_+_4148779 0.17 ENST00000621355.4
ENST00000339123.10
ENST00000278795.7
ENST00000305958.9
ENST00000346595.6
spermine oxidase
chr1_+_202416826 0.17 ENST00000466968.1
protein phosphatase 1 regulatory subunit 12B
chr4_+_6269869 0.17 ENST00000506362.2
wolframin ER transmembrane glycoprotein
chr7_+_73328152 0.17 ENST00000252037.5
ENST00000431982.6
FKBP prolyl isomerase family member 6 (inactive)
chr1_-_201469151 0.17 ENST00000367311.5
ENST00000367309.1
pleckstrin homology like domain family A member 3
chr7_-_100168602 0.16 ENST00000423751.2
ENST00000360039.9
galactose-3-O-sulfotransferase 4
chr7_+_73328177 0.16 ENST00000442793.5
ENST00000413573.6
FKBP prolyl isomerase family member 6 (inactive)
chr1_-_1307861 0.16 ENST00000354700.10
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr19_-_5791155 0.16 ENST00000309061.12
dihydrouridine synthase 3 like
chr5_-_95961830 0.16 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr16_+_142725 0.15 ENST00000652335.1
hemoglobin subunit zeta
chr1_-_6393339 0.15 ENST00000608083.5
acyl-CoA thioesterase 7
chr6_-_132714045 0.15 ENST00000367928.5
vanin 1
chr8_-_142777174 0.15 ENST00000652477.1
ENST00000614491.1
ENST00000613110.4
Ly6/neurotoxin 1
chr14_-_106235582 0.15 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr20_-_23637947 0.15 ENST00000376925.8
cystatin C
chr14_-_103522696 0.15 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr2_-_241508630 0.15 ENST00000403346.7
ENST00000535007.5
serine/threonine kinase 25
chr11_+_61950063 0.15 ENST00000534553.5
bestrophin 1
chr7_-_44885446 0.15 ENST00000395699.5
purine rich element binding protein B
chr19_-_55179390 0.15 ENST00000590851.5
synaptotagmin 5
chr10_+_132186937 0.14 ENST00000338492.9
dihydropyrimidinase like 4
chr12_-_6342066 0.14 ENST00000162749.7
ENST00000440083.6
TNF receptor superfamily member 1A
chr1_-_54053461 0.14 ENST00000371341.5
transmembrane protein 59
chr3_-_39281663 0.14 ENST00000358309.3
C-X3-C motif chemokine receptor 1
chr11_-_65859282 0.14 ENST00000526975.1
ENST00000531413.5
ENST00000525451.6
cofilin 1
chr15_-_42094560 0.14 ENST00000290472.4
phospholipase A2 group IVD
chr20_+_58692767 0.13 ENST00000356091.11
aminopeptidase like 1
chr19_+_55488404 0.13 ENST00000594321.5
ENST00000389623.11
scavenger receptor cysteine rich family member with 5 domains
chr18_-_31042808 0.13 ENST00000434452.5
desmocollin 3
chr2_+_168456215 0.13 ENST00000392687.4
ENST00000305747.11
ceramide synthase 6
chr10_+_90871946 0.13 ENST00000413330.5
ENST00000371703.8
ENST00000277882.7
ribonuclease P/MRP subunit p30
chr1_-_160862880 0.13 ENST00000368034.9
CD244 molecule
chr12_+_12813316 0.13 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DEAD-box helicase 47
chrX_+_71254781 0.12 ENST00000677446.1
non-POU domain containing octamer binding
chr11_-_47378527 0.12 ENST00000378538.8
Spi-1 proto-oncogene
chr1_+_107139996 0.12 ENST00000370073.6
ENST00000370074.8
netrin G1
chr2_-_241617464 0.12 ENST00000402545.5
ENST00000402136.5
THAP domain containing 4
chr9_-_127122623 0.12 ENST00000373417.1
ENST00000373425.8
angiopoietin like 2
chr1_-_45339995 0.12 ENST00000488731.6
ENST00000435155.1
mutY DNA glycosylase
chr1_-_45340381 0.12 ENST00000412971.5
ENST00000372110.7
ENST00000372098.7
ENST00000672818.3
ENST00000529984.5
ENST00000372115.7
mutY DNA glycosylase
chr2_-_241508568 0.11 ENST00000426941.1
ENST00000316586.9
ENST00000405585.5
ENST00000420551.1
ENST00000429279.5
ENST00000442307.5
serine/threonine kinase 25
chr3_+_44338452 0.11 ENST00000396078.7
T cell activation inhibitor, mitochondrial
chr10_+_11742361 0.11 ENST00000379215.9
ENST00000420401.5
enoyl-CoA hydratase domain containing 3
chr1_-_3611470 0.11 ENST00000356575.9
multiple EGF like domains 6
chr4_-_55125585 0.11 ENST00000263923.5
kinase insert domain receptor
chr20_+_49812697 0.11 ENST00000417961.5
solute carrier family 9 member A8
chr22_+_46674593 0.11 ENST00000408031.1
GRAM domain containing 4
chr4_+_677922 0.11 ENST00000400159.6
myosin light chain 5
chr1_+_113905156 0.11 ENST00000650596.1
DNA cross-link repair 1B
chr20_+_49812818 0.11 ENST00000361573.3
solute carrier family 9 member A8
chr5_-_176610104 0.11 ENST00000303991.5
G protein regulated inducer of neurite outgrowth 1
chr15_-_63156774 0.11 ENST00000462430.5
ribosomal protein S27 like
chr2_-_241508547 0.11 ENST00000405883.7
serine/threonine kinase 25
chr20_+_32358303 0.11 ENST00000651418.1
ENST00000375687.10
ENST00000542461.5
ENST00000613218.4
ENST00000646367.1
ENST00000620121.4
ASXL transcriptional regulator 1
chr19_-_42217667 0.11 ENST00000336034.8
ENST00000596251.6
ENST00000598200.1
ENST00000598727.5
death effector domain containing 2
chr20_-_1393074 0.11 ENST00000614856.2
ENST00000678408.1
ENST00000618612.5
ENST00000439640.5
ENST00000381719.8
ENST00000677533.1
FKBP prolyl isomerase 1A
chr8_-_23225061 0.11 ENST00000613472.1
ENST00000221132.8
TNF receptor superfamily member 10a
chr8_-_12194067 0.10 ENST00000524571.6
ENST00000533852.6
ENST00000533513.1
ENST00000448228.6
ENST00000534520.5
family with sequence similarity 86 member B1
chr3_+_44338119 0.10 ENST00000383746.7
ENST00000417237.5
T cell activation inhibitor, mitochondrial
chr1_-_2526585 0.10 ENST00000378466.9
ENST00000435556.8
pantothenate kinase 4 (inactive)
chr11_-_3057386 0.10 ENST00000529772.5
ENST00000278224.13
ENST00000380525.9
cysteinyl-tRNA synthetase 1
chr14_-_74612226 0.10 ENST00000261978.9
latent transforming growth factor beta binding protein 2
chr1_-_45340080 0.10 ENST00000354383.10
ENST00000355498.6
ENST00000531105.5
mutY DNA glycosylase
chr11_-_47378391 0.10 ENST00000227163.8
Spi-1 proto-oncogene
chr11_-_65540610 0.10 ENST00000532661.5
latent transforming growth factor beta binding protein 3
chr16_+_2496032 0.10 ENST00000564543.1
novel protein
chr4_+_51843063 0.10 ENST00000381441.7
ENST00000334635.10
defective in cullin neddylation 1 domain containing 4
chr19_-_14117729 0.10 ENST00000590853.5
ENST00000308677.9
protein kinase cAMP-activated catalytic subunit alpha
chr5_-_113488415 0.09 ENST00000408903.7
MCC regulator of WNT signaling pathway
chr3_+_184176778 0.09 ENST00000439647.5
adaptor related protein complex 2 subunit mu 1
chr17_-_1516621 0.09 ENST00000574561.1
inositol polyphosphate-5-phosphatase K
chr19_-_51646800 0.09 ENST00000599649.5
ENST00000429354.3
ENST00000360844.6
sialic acid binding Ig like lectin 5
sialic acid binding Ig like lectin 14
chr5_+_163437569 0.09 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
cyclin G1
chr17_-_47841173 0.09 ENST00000584123.5
ENST00000578323.1
ENST00000290216.14
ENST00000407215.7
secernin 2
chr16_-_31094727 0.09 ENST00000300851.10
ENST00000394975.3
vitamin K epoxide reductase complex subunit 1
chr9_+_36136416 0.09 ENST00000396613.7
GLI pathogenesis related 2
chr20_-_34955635 0.09 ENST00000644793.1
ENST00000642498.1
ENST00000646735.1
ENST00000644608.1
ENST00000651619.1
glutathione synthetase
chr16_-_31094890 0.09 ENST00000532364.1
ENST00000529564.1
ENST00000319788.11
ENST00000354895.4
novel protein, VKORC1 and PRSS53 readthrough
vitamin K epoxide reductase complex subunit 1
chr5_+_177134159 0.09 ENST00000511258.5
ENST00000347982.8
nuclear receptor binding SET domain protein 1
chr11_+_65879791 0.09 ENST00000528419.6
ENST00000307886.8
ENST00000526034.2
ENST00000679584.1
ENST00000680443.1
ENST00000680670.1
cathepsin W
chr17_-_74859863 0.09 ENST00000293190.10
glutamate ionotropic receptor NMDA type subunit 2C
chr16_-_14694308 0.09 ENST00000438167.8
phospholipase A2 group X
chr12_-_57237090 0.09 ENST00000556732.1
NDUFA4 mitochondrial complex associated like 2
chr11_-_129192198 0.08 ENST00000310343.13
Rho GTPase activating protein 32
chr1_-_209652329 0.08 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chr18_-_36828771 0.08 ENST00000589049.5
ENST00000587129.5
ENST00000590842.5
tubulin polyglutamylase complex subunit 2
chr16_-_31094549 0.08 ENST00000394971.7
vitamin K epoxide reductase complex subunit 1
chr17_-_1516601 0.08 ENST00000421807.7
ENST00000477910.5
ENST00000575172.5
inositol polyphosphate-5-phosphatase K
chr7_+_157139195 0.08 ENST00000389103.4
ubiquitin protein ligase E3C
chr15_+_84817346 0.08 ENST00000258888.6
alpha kinase 3
chr11_-_129192291 0.08 ENST00000682385.1
Rho GTPase activating protein 32
chr17_-_1516699 0.08 ENST00000320345.10
ENST00000406424.8
inositol polyphosphate-5-phosphatase K
chr1_+_54053573 0.08 ENST00000234827.6
transcription elongation factor A N-terminal and central domain containing 2
chr4_+_55346349 0.08 ENST00000505210.1
steroid 5 alpha-reductase 3
chr20_-_1393045 0.08 ENST00000400137.9
ENST00000381715.4
FKBP prolyl isomerase 1A
chr11_+_65181687 0.08 ENST00000527739.5
ENST00000526966.5
ENST00000533129.5
ENST00000524773.5
calpain 1
chr18_-_36829154 0.08 ENST00000614939.4
ENST00000610723.4
tubulin polyglutamylase complex subunit 2
chr4_+_185426234 0.08 ENST00000511138.5
ENST00000511581.5
ENST00000378850.5
chromosome 4 open reading frame 47
chr22_-_36529136 0.08 ENST00000216190.13
ENST00000455547.5
eukaryotic translation initiation factor 3 subunit D
chr1_-_12618198 0.08 ENST00000616661.5
dehydrogenase/reductase 3
chr4_+_2536630 0.08 ENST00000637812.2
family with sequence similarity 193 member A
chr14_+_24232921 0.08 ENST00000557854.5
ENST00000399440.7
ENST00000559104.5
ENST00000456667.7
guanosine monophosphate reductase 2
chr22_-_20320009 0.07 ENST00000405465.3
ENST00000248879.8
DiGeorge syndrome critical region gene 6 like
chr3_+_184176949 0.07 ENST00000432591.5
ENST00000431779.5
ENST00000621863.4
adaptor related protein complex 2 subunit mu 1
chr7_+_129434424 0.07 ENST00000249344.7
ENST00000435494.2
striatin interacting protein 2
chr12_+_108562579 0.07 ENST00000311893.14
ENST00000535729.5
ENST00000431221.6
ENST00000547005.5
ENST00000392807.8
ENST00000539593.1
iron-sulfur cluster assembly enzyme
chr16_-_18433412 0.07 ENST00000620440.4
NODAL modulator 2
chr11_-_2139382 0.07 ENST00000416167.7
insulin like growth factor 2
chr19_+_827823 0.07 ENST00000233997.4
azurocidin 1
chr1_-_156082412 0.07 ENST00000532414.3
mex-3 RNA binding family member A
chr14_-_36521149 0.07 ENST00000518149.5
NK2 homeobox 1
chr22_-_36528897 0.07 ENST00000405442.5
ENST00000402116.2
eukaryotic translation initiation factor 3 subunit D
chr7_-_38349972 0.07 ENST00000390344.2
T cell receptor gamma variable 5
chr11_+_64306227 0.06 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr22_-_22559073 0.06 ENST00000420709.5
ENST00000398741.5
PRAME nuclear receptor transcriptional regulator
chr10_-_71851313 0.06 ENST00000394934.4
ENST00000610929.3
prosaposin
chr2_-_241508318 0.06 ENST00000439101.5
ENST00000424537.5
ENST00000401869.5
ENST00000436402.5
serine/threonine kinase 25
chr17_-_41525326 0.06 ENST00000593096.1
keratin 19
chr4_-_10116724 0.06 ENST00000502702.5
WD repeat domain 1
chr11_+_65181194 0.06 ENST00000533820.5
calpain 1
chrX_-_66639022 0.06 ENST00000374719.8
ectodysplasin A2 receptor
chr10_-_47484081 0.06 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
annexin A8
chr1_-_248859067 0.06 ENST00000496231.1
ENST00000306601.9
ENST00000366471.7
zinc finger protein 692

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.3 1.3 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 2.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 0.5 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.4 GO:0034034 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.3 GO:0046108 uridine metabolic process(GO:0046108)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.5 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.3 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1 0.3 GO:0002339 B cell selection(GO:0002339) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.3 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0070378 positive regulation of ERK5 cascade(GO:0070378)
0.1 0.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.3 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.4 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.2 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.1 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.3 GO:0045007 depurination(GO:0045007)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.9 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.6 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 1.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.4 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) Golgi reassembly(GO:0090168)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238) negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:2000400 pantothenate metabolic process(GO:0015939) positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.4 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.1 0.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:1990357 terminal web(GO:1990357)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0045569 TRAIL binding(GO:0045569)
0.4 2.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.3 GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.4 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0009008 S-methyltransferase activity(GO:0008172) DNA-methyltransferase activity(GO:0009008)
0.1 0.3 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 1.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis