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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for TP63

Z-value: 0.59

Motif logo

Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
ENSG00000073282.14 TP63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg38_v1_chr3_+_189631373_1896315160.349.3e-02Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_57620077 1.67 ENST00000567835.5
ENST00000569372.5
ENST00000563548.5
ENST00000562003.5
adhesion G protein-coupled receptor G1
chr16_+_57619942 1.59 ENST00000568908.5
ENST00000568909.5
ENST00000566778.5
ENST00000561988.5
adhesion G protein-coupled receptor G1
chr18_+_59899988 1.17 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr1_-_209651291 1.02 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr10_+_88990736 1.02 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor
chr6_+_36676489 1.00 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr6_+_36676455 0.99 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chrX_+_152917830 0.81 ENST00000318529.12
zinc finger protein 185 with LIM domain
chrX_-_9765839 0.76 ENST00000467482.6
G protein-coupled receptor 143
chr3_+_53168687 0.59 ENST00000650940.1
ENST00000654719.1
protein kinase C delta
chr14_+_51489112 0.56 ENST00000356218.8
FERM domain containing 6
chr5_+_10564064 0.55 ENST00000296657.7
ankyrin repeat domain 33B
chr6_-_109009498 0.55 ENST00000356644.7
sestrin 1
chr19_+_41219177 0.55 ENST00000301178.9
AXL receptor tyrosine kinase
chrX_+_9912434 0.51 ENST00000418909.6
shroom family member 2
chr15_-_72231583 0.50 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr1_-_150765735 0.49 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr14_-_91244669 0.48 ENST00000650645.1
G protein-coupled receptor 68
chr6_-_100881281 0.48 ENST00000369143.2
ENST00000369162.7
ENST00000324723.10
ENST00000522650.5
activating signal cointegrator 1 complex subunit 3
chr1_+_37692506 0.45 ENST00000373055.6
cell division cycle associated 8
chr11_+_18412292 0.45 ENST00000541669.6
ENST00000280704.8
lactate dehydrogenase C
chr1_+_37692463 0.44 ENST00000327331.2
cell division cycle associated 8
chr19_+_43533384 0.44 ENST00000601282.1
zinc finger protein 575
chr19_+_18386150 0.43 ENST00000252809.3
growth differentiation factor 15
chr17_+_28335571 0.42 ENST00000544907.6
TNF alpha induced protein 1
chr17_+_28335718 0.42 ENST00000226225.7
TNF alpha induced protein 1
chr11_-_78139258 0.41 ENST00000530910.6
ENST00000681417.1
ENST00000681225.1
ENST00000681765.1
ENST00000525870.6
ENST00000530608.6
ENST00000532306.6
ENST00000376156.7
ENST00000681699.1
ENST00000681221.1
ENST00000679444.1
ENST00000680829.1
ENST00000680761.1
ENST00000680256.1
ENST00000525783.6
ENST00000529139.6
ENST00000680580.1
ENST00000526849.6
ENST00000680399.1
ENST00000527099.2
ENST00000681489.1
ENST00000299626.10
ENST00000679497.1
ENST00000680101.1
ENST00000532440.6
ENST00000530454.6
ENST00000525761.3
ENST00000681575.1
ENST00000679559.1
ENST00000680398.1
ENST00000615266.5
ENST00000680643.1
ALG8 alpha-1,3-glucosyltransferase
chr12_+_6494087 0.41 ENST00000382457.8
ENST00000315579.10
non-SMC condensin I complex subunit D2
chr15_-_63157464 0.41 ENST00000330964.10
ENST00000635699.1
ENST00000439025.1
ribosomal protein S27 like
chr19_-_15125095 0.40 ENST00000600984.5
ilvB acetolactate synthase like
chr14_+_24310170 0.38 ENST00000530080.1
leukotriene B4 receptor 2
chr1_-_120054225 0.38 ENST00000602566.6
notch receptor 2
chr19_+_48993864 0.35 ENST00000595090.6
RuvB like AAA ATPase 2
chr4_-_174522315 0.34 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr17_-_4187106 0.33 ENST00000574736.1
ankyrin repeat and FYVE domain containing 1
chr19_+_35358460 0.32 ENST00000327809.5
free fatty acid receptor 3
chr19_+_48321454 0.32 ENST00000599704.5
epithelial membrane protein 3
chr5_+_163437569 0.32 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
cyclin G1
chr1_+_113905290 0.32 ENST00000650450.2
DNA cross-link repair 1B
chr1_+_3690654 0.32 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
tumor protein p73
chr19_+_35371290 0.31 ENST00000597214.1
G protein-coupled receptor 42
chr19_+_15049469 0.31 ENST00000427043.4
caspase 14
chr12_-_14961610 0.31 ENST00000542276.1
Rho GDP dissociation inhibitor beta
chr3_-_191282383 0.31 ENST00000427544.6
urotensin 2B
chr5_-_156963222 0.31 ENST00000407087.4
ENST00000274532.7
T cell immunoglobulin and mucin domain containing 4
chr3_+_44799187 0.30 ENST00000425755.5
kinesin family member 15
chr12_+_68809002 0.30 ENST00000539479.6
ENST00000393415.7
ENST00000523991.5
ENST00000543323.5
ENST00000393416.7
MDM2 proto-oncogene
chr19_+_35358821 0.30 ENST00000594310.1
free fatty acid receptor 3
chr1_-_230745574 0.29 ENST00000681269.1
angiotensinogen
chr22_+_38982341 0.28 ENST00000407298.7
ENST00000333467.4
apolipoprotein B mRNA editing enzyme catalytic subunit 3B
chr19_+_35370929 0.28 ENST00000454971.2
G protein-coupled receptor 42
chr12_-_14961559 0.28 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr22_+_38982370 0.28 ENST00000402182.7
apolipoprotein B mRNA editing enzyme catalytic subunit 3B
chr3_-_14178569 0.27 ENST00000285021.12
XPC complex subunit, DNA damage recognition and repair factor
chr15_-_42094560 0.27 ENST00000290472.4
phospholipase A2 group IVD
chr19_+_43576800 0.26 ENST00000612042.4
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr11_-_111911759 0.25 ENST00000650687.2
crystallin alpha B
chr15_-_88913362 0.25 ENST00000558029.5
ENST00000268150.13
ENST00000542878.5
ENST00000268151.11
ENST00000566497.5
milk fat globule EGF and factor V/VIII domain containing
chr19_-_47231191 0.25 ENST00000439096.3
BCL2 binding component 3
chr11_-_72721908 0.24 ENST00000426523.5
ENST00000429686.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr15_-_63156774 0.24 ENST00000462430.5
ribosomal protein S27 like
chr14_+_22168387 0.24 ENST00000557168.1
T cell receptor alpha variable 30
chr22_+_39014249 0.23 ENST00000361441.5
apolipoprotein B mRNA editing enzyme catalytic subunit 3C
chr8_-_23069012 0.23 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr3_+_138347648 0.22 ENST00000614350.4
ENST00000289104.8
muscle RAS oncogene homolog
chrX_-_154409246 0.22 ENST00000369807.6
deoxyribonuclease 1 like 1
chr11_+_76782250 0.22 ENST00000533752.1
ENST00000612930.1
tsukushi, small leucine rich proteoglycan
chr1_-_150765785 0.22 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr8_-_143840940 0.21 ENST00000442628.7
nuclear receptor binding protein 2
chr19_+_4007714 0.21 ENST00000262971.3
protein inhibitor of activated STAT 4
chr11_-_72722302 0.20 ENST00000334211.12
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr22_-_36529136 0.20 ENST00000216190.13
ENST00000455547.5
eukaryotic translation initiation factor 3 subunit D
chr12_+_108562579 0.20 ENST00000311893.14
ENST00000535729.5
ENST00000431221.6
ENST00000547005.5
ENST00000392807.8
ENST00000539593.1
iron-sulfur cluster assembly enzyme
chr22_-_36528897 0.19 ENST00000405442.5
ENST00000402116.2
eukaryotic translation initiation factor 3 subunit D
chr1_-_205850125 0.19 ENST00000367136.5
peptidase M20 domain containing 1
chr16_+_283157 0.19 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
protein disulfide isomerase family A member 2
chr20_+_836052 0.19 ENST00000246100.3
family with sequence similarity 110 member A
chr21_-_25607474 0.18 ENST00000352957.9
ENST00000419219.1
ENST00000307301.11
mitochondrial ribosomal protein L39
chr1_-_118185157 0.18 ENST00000336338.10
sperm associated antigen 17
chr1_+_42153399 0.18 ENST00000372581.2
guanylate cyclase activator 2B
chr10_-_80289647 0.18 ENST00000372213.8
methionine adenosyltransferase 1A
chr11_+_125887661 0.18 ENST00000425380.7
ENST00000526028.1
HYLS1 centriolar and ciliogenesis associated
chr3_+_19148500 0.17 ENST00000328405.7
potassium voltage-gated channel subfamily H member 8
chr12_-_54648356 0.17 ENST00000293371.11
ENST00000456047.2
dermcidin
chr17_-_74712911 0.17 ENST00000326165.11
ENST00000583937.5
ENST00000301573.13
ENST00000469092.5
CD300 molecule like family member f
chr5_+_175478551 0.17 ENST00000321442.10
ENST00000502393.5
ENST00000506963.1
sideroflexin 1
chr12_-_52493250 0.17 ENST00000330722.7
keratin 6A
chr2_+_109129199 0.16 ENST00000309415.8
SH3 domain containing ring finger 3
chrX_-_130110679 0.16 ENST00000335997.11
E74 like ETS transcription factor 4
chr17_-_63881842 0.16 ENST00000449787.6
ENST00000456543.6
ENST00000622506.4
ENST00000332800.7
ENST00000423893.7
growth hormone 2
chr21_-_17612842 0.16 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chr17_-_44385332 0.16 ENST00000648408.1
integrin subunit alpha 2b
chr21_-_26090035 0.16 ENST00000448850.5
amyloid beta precursor protein
chr15_+_90717321 0.16 ENST00000355112.8
ENST00000681142.1
ENST00000648453.1
ENST00000560509.5
BLM RecQ like helicase
chr12_+_119178953 0.16 ENST00000674542.1
heat shock protein family B (small) member 8
chr17_+_7650916 0.16 ENST00000250111.9
ATPase Na+/K+ transporting subunit beta 2
chrX_-_132218124 0.16 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr12_+_119178920 0.16 ENST00000281938.7
heat shock protein family B (small) member 8
chr8_-_97277890 0.15 ENST00000322128.5
TSPY like 5
chr9_-_136050502 0.15 ENST00000371753.5
NACC family member 2
chr17_+_21376321 0.15 ENST00000583088.6
potassium inwardly rectifying channel subfamily J member 12
chrX_-_130110479 0.15 ENST00000308167.10
E74 like ETS transcription factor 4
chr1_-_220089818 0.15 ENST00000498791.6
ENST00000480959.6
3'(2'), 5'-bisphosphate nucleotidase 1
chr4_-_10116779 0.15 ENST00000499869.7
WD repeat domain 1
chr19_+_507487 0.15 ENST00000359315.6
tubulin polyglutamylase complex subunit 1
chr17_+_4715438 0.15 ENST00000571206.1
arrestin beta 2
chr12_-_88580459 0.14 ENST00000552044.1
ENST00000644744.1
ENST00000357116.4
KIT ligand
chr19_-_57578872 0.14 ENST00000196489.4
zinc finger protein 416
chr20_-_54173976 0.14 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr1_-_32817311 0.14 ENST00000373477.9
ENST00000675785.1
tyrosyl-tRNA synthetase 1
chr5_-_136193143 0.14 ENST00000607574.2
small integral membrane protein 32
chr6_+_106098933 0.14 ENST00000369089.3
PR/SET domain 1
chr20_-_44651683 0.14 ENST00000537820.1
ENST00000372874.9
adenosine deaminase
chr16_-_70695593 0.14 ENST00000567648.1
VAC14 component of PIKFYVE complex
chr8_-_23225061 0.14 ENST00000613472.1
ENST00000221132.8
TNF receptor superfamily member 10a
chr12_-_14961256 0.14 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr6_+_158312459 0.14 ENST00000367097.8
TUB like protein 4
chrX_+_150980504 0.14 ENST00000419110.5
high mobility group box 3
chr7_+_142939343 0.14 ENST00000458732.1
ENST00000409607.5
LLLL and CFNLAS motif containing 1
chr2_-_201642653 0.14 ENST00000621467.4
transmembrane protein 237
chr5_+_73565734 0.13 ENST00000543251.5
ENST00000509005.5
ENST00000296792.9
ENST00000508686.1
ENST00000508491.1
UTP15 small subunit processome component
chr2_+_46941199 0.13 ENST00000319190.11
ENST00000394850.6
tetratricopeptide repeat domain 7A
chr19_-_46784905 0.13 ENST00000594991.5
solute carrier family 1 member 5
chr3_-_9952337 0.13 ENST00000411976.2
ENST00000412055.6
proline rich transmembrane protein 3
chr10_+_11017863 0.13 ENST00000633077.1
ENST00000542579.5
ENST00000632065.1
CUGBP Elav-like family member 2
chrX_+_154379203 0.13 ENST00000369835.3
ENST00000369842.9
emerin
chr3_+_69866217 0.13 ENST00000314589.10
melanocyte inducing transcription factor
chr1_+_17249088 0.13 ENST00000375460.3
peptidyl arginine deiminase 3
chr9_+_116687295 0.13 ENST00000450136.2
ENST00000373983.2
ENST00000411410.1
tripartite motif containing 32
chr16_-_67966793 0.13 ENST00000541864.6
solute carrier family 12 member 4
chr16_+_88803776 0.13 ENST00000301019.9
chromatin licensing and DNA replication factor 1
chr15_-_89690775 0.13 ENST00000559170.1
peroxisomal biogenesis factor 11 alpha
chr11_-_64996963 0.13 ENST00000301887.9
ENST00000534177.1
basic leucine zipper ATF-like transcription factor 2
chrX_-_154374623 0.12 ENST00000369850.10
filamin A
chr18_+_23453275 0.12 ENST00000581585.5
ENST00000339486.8
ENST00000577501.5
RIO kinase 3
chr11_-_8168987 0.12 ENST00000425599.6
ENST00000531450.1
ENST00000309737.11
ENST00000419822.2
ENST00000335425.7
ENST00000343202.8
RIC3 acetylcholine receptor chaperone
chr5_+_180899077 0.12 ENST00000231229.8
ENST00000400707.7
butyrophilin like 8
chr1_+_11980181 0.12 ENST00000444836.5
ENST00000674817.1
ENST00000675053.1
ENST00000675817.1
ENST00000675298.1
ENST00000676369.1
ENST00000412236.2
ENST00000675530.1
ENST00000674548.1
ENST00000674658.1
ENST00000674910.1
ENST00000675231.1
mitofusin 2
chr10_-_74163 0.12 ENST00000564130.2
tubulin beta 8 class VIII
chr14_+_39233908 0.12 ENST00000280082.4
MIA SH3 domain ER export factor 2
chr17_-_74859863 0.12 ENST00000293190.10
glutamate ionotropic receptor NMDA type subunit 2C
chr5_-_132737518 0.12 ENST00000403231.6
ENST00000378735.5
ENST00000618515.4
ENST00000378746.8
kinesin family member 3A
chr8_-_116766255 0.12 ENST00000276682.8
eukaryotic translation initiation factor 3 subunit H
chr6_+_150683593 0.12 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr21_+_42893280 0.11 ENST00000354250.7
NADH:ubiquinone oxidoreductase subunit V3
chr6_+_31666802 0.11 ENST00000617558.2
novel protein
chr21_-_33915762 0.11 ENST00000290299.7
ATP synthase peripheral stalk subunit OSCP
chr19_-_46784733 0.11 ENST00000593713.1
ENST00000598022.1
ENST00000434726.6
solute carrier family 1 member 5
chr17_+_51153551 0.11 ENST00000393196.8
ENST00000336097.7
ENST00000480143.5
ENST00000511355.5
ENST00000393193.6
ENST00000376392.10
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
chr19_-_46413548 0.11 ENST00000307522.5
coiled-coil domain containing 8
chr15_-_89690634 0.11 ENST00000561257.1
peroxisomal biogenesis factor 11 alpha
chr6_+_121435595 0.11 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr4_-_86453075 0.10 ENST00000641384.1
ENST00000642009.1
ENST00000641274.1
ENST00000641629.1
ENST00000641718.1
ENST00000641782.1
ENST00000511328.5
ENST00000503911.5
ENST00000641862.1
ENST00000640445.1
ENST00000641675.1
ENST00000361569.8
ENST00000639989.2
ENST00000641120.1
ENST00000642023.1
ENST00000641902.1
ENST00000641016.1
ENST00000509464.7
ENST00000638946.2
ENST00000395160.9
ENST00000512017.7
ENST00000639972.2
mitogen-activated protein kinase 10
chr6_+_133889105 0.10 ENST00000367882.5
transcription factor 21
chr21_+_42893265 0.10 ENST00000340344.4
NADH:ubiquinone oxidoreductase subunit V3
chr22_-_42614911 0.10 ENST00000617178.4
ENST00000348657.6
ENST00000451060.6
DNA polymerase delta interacting protein 3
chr12_-_122227449 0.10 ENST00000650715.1
diablo IAP-binding mitochondrial protein
chr6_-_42142604 0.10 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr9_-_133739920 0.10 ENST00000371872.8
ENST00000298628.6
sarcosine dehydrogenase
chr2_+_68157877 0.10 ENST00000263657.7
partner of NOB1 homolog
chr19_-_17264718 0.10 ENST00000431146.6
ENST00000594190.5
USH1 protein network component harmonin binding protein 1
chrX_-_153446051 0.10 ENST00000370231.3
three prime repair exonuclease 2
chr10_-_87863533 0.10 ENST00000445946.5
killin, p53 regulated DNA replication inhibitor
chr2_-_33599269 0.10 ENST00000431950.1
ENST00000403368.1
ENST00000238823.13
family with sequence similarity 98 member A
chr8_-_48921419 0.10 ENST00000020945.4
snail family transcriptional repressor 2
chr22_+_35648438 0.10 ENST00000409652.5
apolipoprotein L6
chr20_+_18467382 0.10 ENST00000377603.5
RNA polymerase III subunit F
chr2_-_46941710 0.10 ENST00000409207.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr1_-_157552455 0.10 ENST00000368190.7
ENST00000368189.3
Fc receptor like 5
chr1_+_116373233 0.10 ENST00000295598.10
ATPase Na+/K+ transporting subunit alpha 1
chrX_-_139642518 0.10 ENST00000370573.8
ENST00000338585.6
MCF.2 cell line derived transforming sequence
chr19_-_3500625 0.10 ENST00000672935.1
deoxyhypusine hydroxylase
chr3_+_111911604 0.09 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr17_+_19648915 0.09 ENST00000672567.1
ENST00000672709.1
aldehyde dehydrogenase 3 family member A2
chr2_+_197500371 0.09 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr2_+_100562941 0.09 ENST00000264254.11
phosducin like 3
chr12_-_122227491 0.09 ENST00000475784.1
ENST00000645606.1
novel protein
chr2_+_68974573 0.09 ENST00000673932.3
ENST00000377938.4
gastrokine 1
chr11_+_64306227 0.09 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr22_-_42614871 0.09 ENST00000252115.10
DNA polymerase delta interacting protein 3
chr9_-_116687205 0.09 ENST00000288520.9
ENST00000358637.4
ENST00000341734.8
astrotactin 2
chr12_-_14843517 0.09 ENST00000228936.6
ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
chr11_-_1309604 0.09 ENST00000525159.5
ENST00000527938.5
ENST00000530541.1
ENST00000317204.11
ENST00000263646.11
toll interacting protein
chr1_+_155689074 0.09 ENST00000343043.7
ENST00000421487.6
ENST00000535183.5
ENST00000368336.10
ENST00000465375.5
ENST00000470830.5
death associated protein 3
chr10_+_123154414 0.09 ENST00000368858.9
BUB3 mitotic checkpoint protein
chr10_+_123154768 0.09 ENST00000407911.2
BUB3 mitotic checkpoint protein
chr11_-_128867364 0.09 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr3_-_8963434 0.09 ENST00000418463.5
ENST00000421052.5
ENST00000264926.7
RAD18 E3 ubiquitin protein ligase
chr3_+_44976236 0.08 ENST00000265564.8
exosome component 7
chr5_+_171387757 0.08 ENST00000677297.1
ENST00000521672.6
ENST00000679190.1
ENST00000351986.10
ENST00000676589.1
ENST00000679233.1
ENST00000677357.1
ENST00000296930.10
ENST00000393820.2
ENST00000523622.1
nucleophosmin 1
chr15_+_32615501 0.08 ENST00000361627.8
ENST00000567348.5
ENST00000563864.5
ENST00000543522.5
Rho GTPase activating protein 11A
chr18_+_36544544 0.08 ENST00000591635.5
formin homology 2 domain containing 3
chr11_-_128867268 0.08 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr7_+_45888360 0.08 ENST00000457280.5
insulin like growth factor binding protein 1
chr2_-_164842140 0.08 ENST00000496396.1
ENST00000629362.2
ENST00000445474.2
ENST00000483743.6
cordon-bleu WH2 repeat protein like 1
chr1_-_92961440 0.08 ENST00000370310.5
ENST00000615519.4
ENST00000613902.4
ENST00000616709.4
divergent protein kinase domain 1A
chr18_+_63476927 0.08 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr3_-_53130405 0.08 ENST00000467048.1
ENST00000296292.8
ENST00000394738.7
RFT1 homolog
chrX_+_67543973 0.08 ENST00000374690.9
androgen receptor
chr7_+_45888479 0.08 ENST00000275525.8
ENST00000468955.1
insulin like growth factor binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1902908 regulation of melanosome transport(GO:1902908)
0.2 0.7 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 2.0 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 3.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.6 GO:2000755 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.2 0.6 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 1.0 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.9 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.7 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0036369 transcription factor catabolic process(GO:0036369) cellular response to actinomycin D(GO:0072717)
0.1 1.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 0.3 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0031627 telomeric loop formation(GO:0031627)
0.1 0.2 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:1902905 positive regulation of fibril organization(GO:1902905)
0.1 0.2 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.8 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1 0.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.0 0.2 GO:0043605 cellular amide catabolic process(GO:0043605) regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.1 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0070256 germinal center B cell differentiation(GO:0002314) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) xanthine metabolic process(GO:0046110) negative regulation of mucus secretion(GO:0070256)
0.0 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.5 GO:0014870 response to gravity(GO:0009629) response to muscle inactivity(GO:0014870)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.0 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0071874 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.1 GO:0060599 male genitalia morphogenesis(GO:0048808) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.4 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0031947 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) response to glycoside(GO:1903416)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.4 2.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.0 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.7 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.2 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.5 GO:0033643 host cell part(GO:0033643)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.0 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.6 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.2 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.1 0.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.3 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.8 GO:0035240 dopamine binding(GO:0035240)
0.0 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 3.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.6 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 4.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events