Inflammatory response time course, HUVEC (Wada, 2009)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
UBP1 Links Ensembl NCBI GeneCards UniProt	ENSG00000153560.12	UBP1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
UBP1	hg38_v1_chr3_-_33440343_33440413	0.33	1.0e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr2_+_227813834 Show fit	1.40	ENST00000358813.5 ENST00000409189.7	CCL20 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 20
chr4_+_155666718 Show fit	0.62	ENST00000621234.4 ENST00000511108.5	GUCY1A1 Links Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155666963 Show fit	0.62	ENST00000455639.6	GUCY1A1 Links Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr2_+_161231078 Show fit	0.43	ENST00000439442.1	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr2_-_162318613 Show fit	0.37	ENST00000649979.2 ENST00000421365.2	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr2_-_207769889 Show fit	0.33	ENST00000295417.4	FZD5 Links Ensembl NCBI GeneCards UniProt Show fit	frizzled class receptor 5
chr4_+_155666827 Show fit	0.33	ENST00000511507.5 ENST00000506455.6	GUCY1A1 Links Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr13_+_24270681 Show fit	0.32	ENST00000343003.10 ENST00000399949.6	SPATA13 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 13
chr11_+_7485492 Show fit	0.29	ENST00000534244.1 ENST00000329293.4	OLFML1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactomedin like 1
chr17_+_76385256 Show fit	0.29	ENST00000392496.3	SPHK1 Links Ensembl NCBI GeneCards UniProt Show fit	sphingosine kinase 1
chr14_-_91946989 Show fit	0.23	ENST00000556154.5	FBLN5 Links Ensembl NCBI GeneCards UniProt Show fit	fibulin 5
chr2_-_162318129 Show fit	0.22	ENST00000679938.1	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr19_-_49361475 Show fit	0.22	ENST00000598810.5	TEAD2 Links Ensembl NCBI GeneCards UniProt Show fit	TEA domain transcription factor 2
chr5_-_111757549 Show fit	0.21	ENST00000419114.6	NREP Links Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr5_-_111758061 Show fit	0.20	ENST00000509979.5 ENST00000513100.5 ENST00000508161.5 ENST00000455559.6	NREP Links Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr5_-_111757704 Show fit	0.18	ENST00000379671.7	NREP Links Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr5_-_111757643 Show fit	0.17	ENST00000508870.5	NREP Links Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr10_+_21524627 Show fit	0.16	ENST00000651097.1	MLLT10 Links Ensembl NCBI GeneCards UniProt Show fit	MLLT10 histone lysine methyltransferase DOT1L cofactor
chr3_+_111542134 Show fit	0.16	ENST00000438817.6	CD96 Links Ensembl NCBI GeneCards UniProt Show fit	CD96 molecule
chr4_-_176195563 Show fit	0.15	ENST00000280191.7	SPATA4 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 4
chr2_-_162318475 Show fit	0.15	ENST00000648433.1	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr1_-_150235943 Show fit	0.15	ENST00000533654.5	ANP32E Links Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chr1_-_150235972 Show fit	0.15	ENST00000534220.1	ANP32E Links Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chr12_+_99647749 Show fit	0.13	ENST00000324341.2	FAM71C Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 71 member C
chr3_-_98523013 Show fit	0.13	ENST00000394181.6 ENST00000508902.5 ENST00000394180.6	CLDND1 Links Ensembl NCBI GeneCards UniProt Show fit	claudin domain containing 1
chr3_-_150763093 Show fit	0.12	ENST00000312960.4	SIAH2 Links Ensembl NCBI GeneCards UniProt Show fit	siah E3 ubiquitin protein ligase 2
chr11_-_31803620 Show fit	0.11	ENST00000639006.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr14_-_91947383 Show fit	0.11	ENST00000267620.14	FBLN5 Links Ensembl NCBI GeneCards UniProt Show fit	fibulin 5
chr17_-_79009778 Show fit	0.11	ENST00000591773.5 ENST00000588611.5 ENST00000586916.6 ENST00000592033.5 ENST00000588075.5 ENST00000302345.6 ENST00000591811.1	CANT1 Links Ensembl NCBI GeneCards UniProt Show fit	calcium activated nucleotidase 1
chr11_-_31803663 Show fit	0.11	ENST00000638802.1 ENST00000638878.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr22_+_22375984 Show fit	0.10	ENST00000390296.2	IGLV5-45 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 5-45
chr1_-_150235995 Show fit	0.10	ENST00000436748.6	ANP32E Links Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chr5_-_131994225 Show fit	0.10	ENST00000543479.5 ENST00000431707.5	ACSL6 Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 6
chr12_-_14938508 Show fit	0.10	ENST00000266397.7	ERP27 Links Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum protein 27
chr1_-_150697128 Show fit	0.09	ENST00000427665.1 ENST00000271732.8	GOLPH3L Links Ensembl NCBI GeneCards UniProt Show fit	golgi phosphoprotein 3 like
chr2_-_227379297 Show fit	0.09	ENST00000304568.4	TM4SF20 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 20
chr19_-_4581755 Show fit	0.09	ENST00000676793.1	SEMA6B Links Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6B
chr10_-_49134021 Show fit	0.09	ENST00000311787.6	FAM170B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 170 member B
chr5_+_150671588 Show fit	0.08	ENST00000523553.1	MYOZ3 Links Ensembl NCBI GeneCards UniProt Show fit	myozenin 3
chr17_-_79009731 Show fit	0.08	ENST00000392446.10 ENST00000590370.5 ENST00000591625.5	CANT1 Links Ensembl NCBI GeneCards UniProt Show fit	calcium activated nucleotidase 1
chr5_+_80035341 Show fit	0.08	ENST00000350881.6	THBS4 Links Ensembl NCBI GeneCards UniProt Show fit	thrombospondin 4
chr7_+_133253064 Show fit	0.08	ENST00000393161.6 ENST00000253861.5	EXOC4 Links Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 4
chrX_+_71254781 Show fit	0.08	ENST00000677446.1	NONO Links Ensembl NCBI GeneCards UniProt Show fit	non-POU domain containing octamer binding
chr1_+_17580474 Show fit	0.07	ENST00000375415.5	ARHGEF10L Links Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 10 like
chrX_+_54920796 Show fit	0.07	ENST00000442098.5 ENST00000430420.5 ENST00000453081.5 ENST00000319167.12 ENST00000622017.4 ENST00000375022.8 ENST00000399736.5 ENST00000440072.5 ENST00000173898.12 ENST00000431115.5 ENST00000440759.5 ENST00000375041.6	TRO Links Ensembl NCBI GeneCards UniProt Show fit	trophinin
chr19_-_54100792 Show fit	0.07	ENST00000391761.5 ENST00000356532.7 ENST00000616447.4 ENST00000359649.8 ENST00000358375.8 ENST00000391760.1 ENST00000351806.8	OSCAR Links Ensembl NCBI GeneCards UniProt Show fit	osteoclast associated Ig-like receptor
chr3_-_142888896 Show fit	0.07	ENST00000485766.1	PCOLCE2 Links Ensembl NCBI GeneCards UniProt Show fit	procollagen C-endopeptidase enhancer 2
chr4_-_119300546 Show fit	0.07	ENST00000504110.2	C4orf3 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 4 open reading frame 3
chr1_+_45012691 Show fit	0.06	ENST00000469548.5	UROD Links Ensembl NCBI GeneCards UniProt Show fit	uroporphyrinogen decarboxylase
chr3_+_111998915 Show fit	0.06	ENST00000478951.6	TAGLN3 Links Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr1_-_150236064 Show fit	0.06	ENST00000532744.2 ENST00000369114.9 ENST00000369115.3 ENST00000583931.6	ANP32E Links Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chr5_-_94111627 Show fit	0.06	ENST00000505869.5 ENST00000395965.8 ENST00000509163.5	FAM172A Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 172 member A
chr2_-_89010515 Show fit	0.06	ENST00000493819.1	IGKV1-9 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr4_-_167234579 Show fit	0.05	ENST00000502330.5 ENST00000357154.7 ENST00000421836.6	SPOCK3 Links Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr4_-_167234426 Show fit	0.05	ENST00000541354.5 ENST00000509854.5 ENST00000512681.5 ENST00000357545.9 ENST00000510741.5 ENST00000510403.5	SPOCK3 Links Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr6_+_6588082 Show fit	0.05	ENST00000379953.6	LY86 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 86
chr22_+_22811737 Show fit	0.05	ENST00000390315.3	IGLV3-10 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-10
chr8_-_106770235 Show fit	0.05	ENST00000311955.4	ABRA Links Ensembl NCBI GeneCards UniProt Show fit	actin binding Rho activating protein
chr3_+_111999189 Show fit	0.05	ENST00000455401.6	TAGLN3 Links Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chrX_-_15664798 Show fit	0.05	ENST00000380342.4	CLTRN Links Ensembl NCBI GeneCards UniProt Show fit	collectrin, amino acid transport regulator
chr11_-_125592448 Show fit	0.05	ENST00000648911.1	FEZ1 Links Ensembl NCBI GeneCards UniProt Show fit	fasciculation and elongation protein zeta 1
chr1_+_155135807 Show fit	0.05	ENST00000368401.6 ENST00000622581.4	SLC50A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 50 member 1
chr2_-_178478541 Show fit	0.04	ENST00000424785.7	FKBP7 Links Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 7
chr21_+_42403874 Show fit	0.04	ENST00000319294.11 ENST00000398367.1	UBASH3A Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin associated and SH3 domain containing A
chr1_+_155135817 Show fit	0.04	ENST00000303343.12 ENST00000368404.9	SLC50A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 50 member 1
chr11_-_65084024 Show fit	0.04	ENST00000275517.8 ENST00000404147.3	CDCA5 Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle associated 5
chr17_+_42853232 Show fit	0.04	ENST00000617500.4	AOC3 Links Ensembl NCBI GeneCards UniProt Show fit	amine oxidase copper containing 3
chr17_-_50373173 Show fit	0.03	ENST00000225969.9 ENST00000503633.5 ENST00000442592.3	MRPL27 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L27
chr1_-_150236150 Show fit	0.03	ENST00000629042.2	ANP32E Links Ensembl NCBI GeneCards UniProt Show fit	acidic nuclear phosphoprotein 32 family member E
chrX_+_116436599 Show fit	0.03	ENST00000598581.3	SLC6A14 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 14
chr12_+_80716906 Show fit	0.03	ENST00000228644.4	MYF5 Links Ensembl NCBI GeneCards UniProt Show fit	myogenic factor 5
chr1_-_152360004 Show fit	0.03	ENST00000388718.5	FLG2 Links Ensembl NCBI GeneCards UniProt Show fit	filaggrin family member 2
chr6_-_47042260 Show fit	0.03	ENST00000371243.2	ADGRF1 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor F1
chr22_-_36817510 Show fit	0.03	ENST00000443735.1	PVALB Links Ensembl NCBI GeneCards UniProt Show fit	parvalbumin
chr1_+_48222685 Show fit	0.03	ENST00000533824.5 ENST00000236495.9 ENST00000438567.7	SLC5A9 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 5 member 9
chr2_+_186590022 Show fit	0.02	ENST00000261023.8 ENST00000374907.7	ITGAV Links Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha V
chr17_-_3292600 Show fit	0.02	ENST00000615105.1	OR3A1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 3 subfamily A member 1
chr1_-_155244684 Show fit	0.02	ENST00000428024.3	GBA Links Ensembl NCBI GeneCards UniProt Show fit	glucosylceramidase beta
chr1_-_182672882 Show fit	0.02	ENST00000367557.8 ENST00000258302.8	RGS8 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 8
chr1_-_168729187 Show fit	0.02	ENST00000367817.4	DPT Links Ensembl NCBI GeneCards UniProt Show fit	dermatopontin
chr4_-_82430192 Show fit	0.02	ENST00000621267.4 ENST00000614627.4	HNRNPDL Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein D like
chr10_+_103493931 Show fit	0.02	ENST00000369780.8	NEURL1 Links Ensembl NCBI GeneCards UniProt Show fit	neuralized E3 ubiquitin protein ligase 1
chr12_+_57583101 Show fit	0.01	ENST00000674858.1 ENST00000675433.1 ENST00000674980.1	KIF5A Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 5A
chr12_-_122422662 Show fit	0.01	ENST00000620786.5	CLIP1 Links Ensembl NCBI GeneCards UniProt Show fit	CAP-Gly domain containing linker protein 1
chr1_-_182672232 Show fit	0.01	ENST00000508450.5	RGS8 Links Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 8
chr9_-_35685462 Show fit	0.01	ENST00000607559.1	TPM2 Links Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 2
chr19_-_51034892 Show fit	0.01	ENST00000319590.8 ENST00000250351.4	KLK12 Links Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 12
chr19_+_49361783 Show fit	0.01	ENST00000594268.1	DKKL1 Links Ensembl NCBI GeneCards UniProt Show fit	dickkopf like acrosomal protein 1
chr3_-_98522869 Show fit	0.01	ENST00000502288.5 ENST00000512147.5 ENST00000341181.11 ENST00000510541.5 ENST00000503621.5 ENST00000511081.5 ENST00000507874.5 ENST00000502299.5 ENST00000508659.5 ENST00000510545.5 ENST00000511667.5 ENST00000394185.6	CLDND1 Links Ensembl NCBI GeneCards UniProt Show fit	claudin domain containing 1
chr5_-_151141631 Show fit	0.00	ENST00000523714.5 ENST00000521749.5	ANXA6 Links Ensembl NCBI GeneCards UniProt Show fit	annexin A6
chr2_+_169694434 Show fit	0.00	ENST00000616481.4 ENST00000616524.4 ENST00000617738.4 ENST00000359744.8 ENST00000438838.5 ENST00000438710.5 ENST00000449906.5 ENST00000498202.6 ENST00000272797.8	PHOSPHO2 Links Ensembl NCBI GeneCards UniProt Show fit KLHL23 Links Ensembl NCBI GeneCards UniProt Show fit	phosphatase, orphan 2 kelch like family member 23
chr16_+_31108294 Show fit	0.00	ENST00000287507.7 ENST00000394950.7 ENST00000219794.11 ENST00000561755.1	BCKDK Links Ensembl NCBI GeneCards UniProt Show fit	branched chain keto acid dehydrogenase kinase

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1	0.7	GO:0034343	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1	0.3	GO:0046521	sphingoid catabolic process(GO:0046521)
0.1	0.3	GO:1901382	Spemann organizer formation(GO:0060061) chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1	0.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0	0.1	GO:0002728	negative regulation of natural killer cell cytokine production(GO:0002728)
0.0	0.1	GO:0042946	glucoside transport(GO:0042946)
0.0	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
0.0	0.1	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.2	GO:0003322	pancreatic A cell development(GO:0003322)
0.0	0.2	GO:0048368	lateral mesoderm development(GO:0048368)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.0	0.3	GO:0071953	elastic fiber(GO:0071953)
0.0	0.5	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.1	GO:0002081	outer acrosomal membrane(GO:0002081)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.1	0.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.2	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.0	0.3	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0	0.1	GO:0042947	glucoside transmembrane transporter activity(GO:0042947)
0.0	0.1	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation