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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for UGGCACU

Z-value: 0.74

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miRNA associated with seed UGGCACU

NamemiRBASE accession
hsa-miR-183-5p.2

Activity profile of UGGCACU motif

Sorted Z-values of UGGCACU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UGGCACU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_23135452 3.68 ENST00000580153.5
ENST00000256925.12
CABLES1
Cdk5 and Abl enzyme substrate 1
chr3_+_39809602 3.36 ENST00000302541.11
ENST00000396217.7
MYRIP
myosin VIIA and Rab interacting protein
chr9_+_76459152 3.08 ENST00000444201.6
ENST00000376730.5
GCNT1
glucosaminyl (N-acetyl) transferase 1
chr4_-_16898619 2.88 ENST00000502640.5
ENST00000304523.10
ENST00000506732.1
LDB2
LIM domain binding 2
chr5_-_100903252 2.82 ENST00000231461.10
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr12_+_27244222 2.67 ENST00000545470.5
ENST00000389032.8
ENST00000540996.5
STK38L
serine/threonine kinase 38 like
chr1_-_209806124 2.66 ENST00000367021.8
ENST00000542854.5
IRF6
interferon regulatory factor 6
chr10_+_110871903 2.61 ENST00000280154.12
PDCD4
programmed cell death 4
chr6_-_16761447 2.06 ENST00000244769.8
ENST00000436367.6
ATXN1
ataxin 1
chr13_+_57631735 1.99 ENST00000377918.8
PCDH17
protocadherin 17
chr8_+_96493803 1.87 ENST00000518385.5
ENST00000302190.9
SDC2
syndecan 2
chr8_+_37796906 1.80 ENST00000315215.11
ADGRA2
adhesion G protein-coupled receptor A2
chr6_+_11537738 1.78 ENST00000379426.2
TMEM170B
transmembrane protein 170B
chr2_+_172735912 1.77 ENST00000409036.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr1_+_76074698 1.68 ENST00000328299.4
ST6GALNAC3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr2_+_158456939 1.62 ENST00000389759.8
ENST00000628904.2
ENST00000389757.7
PKP4
plakophilin 4
chr13_+_26557659 1.58 ENST00000335327.6
ENST00000361042.8
ENST00000671038.1
WASF3
WASP family member 3
chr9_+_112750722 1.28 ENST00000374232.8
SNX30
sorting nexin family member 30
chr19_+_32405789 1.27 ENST00000586987.5
DPY19L3
dpy-19 like C-mannosyltransferase 3
chr5_+_149581368 1.26 ENST00000333677.7
ARHGEF37
Rho guanine nucleotide exchange factor 37
chr1_-_54887161 1.22 ENST00000535035.6
ENST00000371269.9
ENST00000436604.2
DHCR24
24-dehydrocholesterol reductase
chr12_-_95790755 1.20 ENST00000343702.9
ENST00000344911.8
NTN4
netrin 4
chr4_-_113761927 1.18 ENST00000296402.9
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr20_+_38805686 1.16 ENST00000299824.6
ENST00000373331.2
PPP1R16B
protein phosphatase 1 regulatory subunit 16B
chr17_+_49788672 1.13 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
KAT7
lysine acetyltransferase 7
chr19_-_14206168 1.11 ENST00000361434.7
ENST00000340736.10
ADGRL1
adhesion G protein-coupled receptor L1
chr12_-_118103998 1.08 ENST00000359236.10
VSIG10
V-set and immunoglobulin domain containing 10
chr9_-_14314067 1.07 ENST00000397575.7
NFIB
nuclear factor I B
chr18_+_13218769 1.07 ENST00000677055.1
ENST00000399848.7
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr8_-_80874771 1.06 ENST00000327835.7
ZNF704
zinc finger protein 704
chr11_-_83071819 1.05 ENST00000524635.1
ENST00000526205.5
ENST00000533486.5
ENST00000533276.6
ENST00000527633.6
RAB30
RAB30, member RAS oncogene family
chr9_-_10612966 1.01 ENST00000381196.9
PTPRD
protein tyrosine phosphatase receptor type D
chr16_-_4116403 1.00 ENST00000294016.8
ADCY9
adenylate cyclase 9
chr9_+_2015335 0.95 ENST00000636559.1
ENST00000349721.8
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_+_11976709 0.95 ENST00000566228.6
SNX29
sorting nexin 29
chr4_+_77157189 0.95 ENST00000316355.10
ENST00000502280.5
CCNG2
cyclin G2
chr7_+_17298642 0.94 ENST00000242057.9
AHR
aryl hydrocarbon receptor
chr22_+_23180365 0.92 ENST00000359540.7
ENST00000305877.13
BCR
BCR activator of RhoGEF and GTPase
chr3_-_18425295 0.91 ENST00000338745.11
ENST00000450898.1
SATB1
SATB homeobox 1
chr17_+_50095331 0.85 ENST00000503176.6
PDK2
pyruvate dehydrogenase kinase 2
chr3_-_171460368 0.84 ENST00000436636.7
ENST00000465393.1
ENST00000341852.10
TNIK
TRAF2 and NCK interacting kinase
chr3_-_15859771 0.84 ENST00000399451.6
ANKRD28
ankyrin repeat domain 28
chr9_+_4490388 0.84 ENST00000262352.8
SLC1A1
solute carrier family 1 member 1
chr7_+_44606619 0.83 ENST00000222673.6
ENST00000444676.5
ENST00000631326.2
OGDH
oxoglutarate dehydrogenase
chr1_-_20486197 0.82 ENST00000375078.4
CAMK2N1
calcium/calmodulin dependent protein kinase II inhibitor 1
chr2_+_45651650 0.78 ENST00000306156.8
PRKCE
protein kinase C epsilon
chr11_-_45665578 0.76 ENST00000308064.7
CHST1
carbohydrate sulfotransferase 1
chr12_+_59689337 0.74 ENST00000261187.8
SLC16A7
solute carrier family 16 member 7
chr11_+_114059702 0.69 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
ZBTB16
zinc finger and BTB domain containing 16
chr12_+_93377883 0.69 ENST00000337179.9
ENST00000415493.7
NUDT4
nudix hydrolase 4
chr12_-_12267003 0.67 ENST00000535731.1
ENST00000261349.9
LRP6
LDL receptor related protein 6
chrX_-_54496212 0.67 ENST00000375135.4
FGD1
FYVE, RhoGEF and PH domain containing 1
chr2_-_196171565 0.66 ENST00000263955.9
STK17B
serine/threonine kinase 17b
chr14_-_74084393 0.62 ENST00000350259.8
ENST00000553458.6
ALDH6A1
aldehyde dehydrogenase 6 family member A1
chr5_+_58583068 0.61 ENST00000282878.6
RAB3C
RAB3C, member RAS oncogene family
chr7_+_143288215 0.61 ENST00000619992.4
ENST00000310447.10
CASP2
caspase 2
chr7_-_27143672 0.61 ENST00000222726.4
HOXA5
homeobox A5
chr20_+_11890723 0.59 ENST00000254977.7
BTBD3
BTB domain containing 3
chr10_+_70404129 0.57 ENST00000373218.5
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr8_-_123274255 0.57 ENST00000622816.2
ENST00000395571.8
ZHX1-C8orf76
ZHX1
ZHX1-C8orf76 readthrough
zinc fingers and homeoboxes 1
chr7_-_15686671 0.57 ENST00000262041.6
MEOX2
mesenchyme homeobox 2
chr9_-_104928139 0.56 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ABCA1
ATP binding cassette subfamily A member 1
chr10_+_61901678 0.55 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
ARID5B
AT-rich interaction domain 5B
chr1_-_67833448 0.54 ENST00000370982.4
GNG12
G protein subunit gamma 12
chr9_-_72364504 0.53 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
ZFAND5
zinc finger AN1-type containing 5
chr10_-_100185993 0.50 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ERLIN1
ER lipid raft associated 1
chr16_-_23510389 0.49 ENST00000562117.1
ENST00000567468.5
ENST00000562944.5
ENST00000309859.8
GGA2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr15_-_44194407 0.49 ENST00000484674.5
FRMD5
FERM domain containing 5
chr4_+_107824555 0.49 ENST00000394684.8
SGMS2
sphingomyelin synthase 2
chr11_+_117178728 0.48 ENST00000532960.5
ENST00000324225.9
SIDT2
SID1 transmembrane family member 2
chr1_+_203626775 0.47 ENST00000367218.7
ATP2B4
ATPase plasma membrane Ca2+ transporting 4
chr9_+_88388356 0.46 ENST00000375859.4
SPIN1
spindlin 1
chr11_+_120336357 0.46 ENST00000397843.7
ARHGEF12
Rho guanine nucleotide exchange factor 12
chr1_+_28369705 0.45 ENST00000373839.8
PHACTR4
phosphatase and actin regulator 4
chr2_-_44361754 0.45 ENST00000409272.5
ENST00000410081.5
ENST00000541738.5
PREPL
prolyl endopeptidase like
chr4_-_77819356 0.43 ENST00000649644.1
ENST00000504123.6
ENST00000515441.2
CNOT6L
CCR4-NOT transcription complex subunit 6 like
chr7_+_107168961 0.42 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HBP1
HMG-box transcription factor 1
chr11_+_74748831 0.41 ENST00000299563.5
RNF169
ring finger protein 169
chr14_+_57268963 0.41 ENST00000261558.8
AP5M1
adaptor related protein complex 5 subunit mu 1
chr3_-_56468346 0.41 ENST00000288221.11
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr2_+_202634960 0.41 ENST00000392238.3
FAM117B
family with sequence similarity 117 member B
chr1_-_221742074 0.40 ENST00000366899.4
DUSP10
dual specificity phosphatase 10
chr18_-_55588184 0.40 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
TCF4
transcription factor 4
chr9_-_109119915 0.40 ENST00000374586.8
TMEM245
transmembrane protein 245
chrX_+_16946650 0.39 ENST00000357277.8
REPS2
RALBP1 associated Eps domain containing 2
chrX_-_84188148 0.39 ENST00000262752.5
RPS6KA6
ribosomal protein S6 kinase A6
chr13_+_102596972 0.39 ENST00000376052.5
ENST00000376065.8
ENST00000652308.1
ENST00000651544.1
TPP2
tripeptidyl peptidase 2
chr3_+_57227714 0.38 ENST00000288266.8
APPL1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
chr8_+_73294594 0.38 ENST00000240285.10
RDH10
retinol dehydrogenase 10
chr9_-_4741176 0.38 ENST00000381809.8
AK3
adenylate kinase 3
chr6_-_158818225 0.37 ENST00000337147.11
EZR
ezrin
chr2_+_120252837 0.37 ENST00000272519.10
ENST00000631312.2
RALB
RAS like proto-oncogene B
chr1_-_52552994 0.36 ENST00000355809.4
ENST00000528642.5
ENST00000470626.1
ENST00000257177.9
ENST00000371544.7
TUT4
terminal uridylyl transferase 4
chr13_-_75482151 0.35 ENST00000377636.8
TBC1D4
TBC1 domain family member 4
chr6_-_89819699 0.35 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
MDN1
midasin AAA ATPase 1
chrX_-_19887585 0.34 ENST00000397821.8
SH3KBP1
SH3 domain containing kinase binding protein 1
chr6_+_160991727 0.34 ENST00000366919.6
ENST00000392142.9
ENST00000366920.6
ENST00000348824.11
MAP3K4
mitogen-activated protein kinase kinase kinase 4
chr12_-_109573482 0.34 ENST00000540016.5
ENST00000545712.7
MMAB
metabolism of cobalamin associated B
chr15_-_34336749 0.33 ENST00000397707.6
ENST00000560611.5
SLC12A6
solute carrier family 12 member 6
chr2_-_208025494 0.33 ENST00000457206.1
ENST00000427836.8
PLEKHM3
pleckstrin homology domain containing M3
chr8_-_123541197 0.32 ENST00000517956.5
ENST00000443022.2
FBXO32
F-box protein 32
chr5_+_102755269 0.32 ENST00000304400.12
ENST00000455264.7
ENST00000684529.1
ENST00000438793.8
ENST00000682882.1
ENST00000682972.1
ENST00000348126.7
ENST00000512073.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr6_-_34392627 0.32 ENST00000607016.2
NUDT3
nudix hydrolase 3
chr12_+_113185702 0.32 ENST00000548278.2
RITA1
RBPJ interacting and tubulin associated 1
chr1_+_201829132 0.31 ENST00000361565.9
IPO9
importin 9
chr19_+_18097763 0.31 ENST00000262811.10
MAST3
microtubule associated serine/threonine kinase 3
chr2_+_209579399 0.31 ENST00000360351.8
MAP2
microtubule associated protein 2
chr3_+_170222412 0.30 ENST00000295797.5
PRKCI
protein kinase C iota
chr9_-_123184233 0.29 ENST00000447404.6
STRBP
spermatid perinuclear RNA binding protein
chr11_-_95231046 0.29 ENST00000416495.6
ENST00000536441.7
SESN3
sestrin 3
chr14_-_91417805 0.29 ENST00000389857.11
ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr17_+_63622406 0.29 ENST00000579585.5
ENST00000361733.8
ENST00000584573.5
ENST00000361357.7
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr13_-_40666600 0.29 ENST00000379561.6
FOXO1
forkhead box O1
chr9_-_113299196 0.29 ENST00000441031.3
RNF183
ring finger protein 183
chr3_+_152299392 0.29 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
MBNL1
muscleblind like splicing regulator 1
chr19_+_1753499 0.28 ENST00000382349.5
ONECUT3
one cut homeobox 3
chr17_+_68512379 0.28 ENST00000392711.5
ENST00000585427.5
ENST00000589228.6
ENST00000536854.6
ENST00000588702.5
ENST00000589309.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr6_-_79078247 0.27 ENST00000275034.5
PHIP
pleckstrin homology domain interacting protein
chr12_+_12891554 0.27 ENST00000014914.6
GPRC5A
G protein-coupled receptor class C group 5 member A
chrX_-_115234088 0.27 ENST00000317135.13
LRCH2
leucine rich repeats and calponin homology domain containing 2
chr3_-_142000353 0.27 ENST00000499676.5
TFDP2
transcription factor Dp-2
chr15_-_52569197 0.26 ENST00000563277.5
ENST00000566423.5
ARPP19
cAMP regulated phosphoprotein 19
chr16_-_47143934 0.25 ENST00000562435.6
NETO2
neuropilin and tolloid like 2
chr19_-_33064872 0.25 ENST00000254260.8
RHPN2
rhophilin Rho GTPase binding protein 2
chr1_-_77682639 0.25 ENST00000370801.8
ENST00000433749.5
ZZZ3
zinc finger ZZ-type containing 3
chr9_+_128882119 0.24 ENST00000372600.9
ENST00000372599.7
LRRC8A
leucine rich repeat containing 8 VRAC subunit A
chr11_+_57753243 0.24 ENST00000524630.5
ENST00000529919.5
ENST00000533189.1
CTNND1
catenin delta 1
chr8_-_81842192 0.24 ENST00000353788.8
ENST00000520618.5
ENST00000518183.5
ENST00000396330.6
ENST00000519119.5
SNX16
sorting nexin 16
chr6_+_124962420 0.24 ENST00000521654.7
ENST00000560949.5
RNF217
ring finger protein 217
chr1_+_109249530 0.24 ENST00000271332.4
CELSR2
cadherin EGF LAG seven-pass G-type receptor 2
chr13_-_30464234 0.24 ENST00000399489.5
ENST00000339872.8
HMGB1
high mobility group box 1
chr3_+_169966764 0.23 ENST00000337002.9
ENST00000480708.5
SEC62
SEC62 homolog, preprotein translocation factor
chr7_+_5190196 0.23 ENST00000401525.7
ENST00000288828.9
ENST00000404704.7
WIPI2
WD repeat domain, phosphoinositide interacting 2
chr2_+_204545446 0.23 ENST00000406610.7
PARD3B
par-3 family cell polarity regulator beta
chr12_-_92145838 0.22 ENST00000256015.5
BTG1
BTG anti-proliferation factor 1
chr1_-_109397888 0.22 ENST00000256637.8
SORT1
sortilin 1
chr1_+_3069160 0.22 ENST00000511072.5
PRDM16
PR/SET domain 16
chr11_-_6655788 0.22 ENST00000299441.5
DCHS1
dachsous cadherin-related 1
chr1_+_109466527 0.22 ENST00000369872.4
SYPL2
synaptophysin like 2
chr2_+_190408324 0.21 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
MFSD6
major facilitator superfamily domain containing 6
chr16_-_20900319 0.21 ENST00000564349.5
ENST00000324344.9
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
defective in cullin neddylation 1 domain containing 3
chr3_-_72446623 0.21 ENST00000477973.4
RYBP
RING1 and YY1 binding protein
chr1_+_230067198 0.21 ENST00000366672.5
GALNT2
polypeptide N-acetylgalactosaminyltransferase 2
chr8_+_85177225 0.21 ENST00000418930.6
E2F5
E2F transcription factor 5
chr1_-_153922901 0.20 ENST00000634401.1
ENST00000368655.5
GATAD2B
GATA zinc finger domain containing 2B
chr2_-_99489955 0.20 ENST00000393445.7
ENST00000258428.8
REV1
REV1 DNA directed polymerase
chr10_+_101061973 0.20 ENST00000370200.6
KAZALD1
Kazal type serine peptidase inhibitor domain 1
chr12_-_57237090 0.20 ENST00000556732.1
NDUFA4L2
NDUFA4 mitochondrial complex associated like 2
chr4_-_176002332 0.19 ENST00000280187.11
ENST00000512509.5
GPM6A
glycoprotein M6A
chr21_-_38498415 0.19 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chr6_+_52362088 0.19 ENST00000635984.1
ENST00000635760.1
ENST00000442253.3
EFHC1
PAQR8
EF-hand domain containing 1
progestin and adipoQ receptor family member 8
chrX_-_24027186 0.19 ENST00000328046.8
KLHL15
kelch like family member 15
chr1_-_118989504 0.19 ENST00000207157.7
TBX15
T-box transcription factor 15
chr5_+_157743703 0.18 ENST00000286307.6
LSM11
LSM11, U7 small nuclear RNA associated
chr20_-_33674359 0.18 ENST00000606690.5
ENST00000439478.5
ENST00000246190.11
ENST00000375238.8
NECAB3
N-terminal EF-hand calcium binding protein 3
chr22_+_29883158 0.18 ENST00000333027.7
ENST00000401950.7
ENST00000445401.5
ENST00000323630.9
ENST00000351488.7
MTMR3
myotubularin related protein 3
chr1_+_113390495 0.18 ENST00000307546.14
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr6_+_87472925 0.18 ENST00000369556.7
ENST00000369557.9
ENST00000369552.9
SLC35A1
solute carrier family 35 member A1
chr12_-_40106026 0.18 ENST00000280871.9
ENST00000380858.1
SLC2A13
solute carrier family 2 member 13
chr12_-_48788995 0.17 ENST00000550422.5
ENST00000357869.8
ADCY6
adenylate cyclase 6
chr2_+_46617180 0.17 ENST00000238892.4
CRIPT
CXXC repeat containing interactor of PDZ3 domain
chr7_-_72336995 0.17 ENST00000329008.9
CALN1
calneuron 1
chr14_-_103057509 0.17 ENST00000361246.7
CDC42BPB
CDC42 binding protein kinase beta
chr2_+_20447065 0.16 ENST00000272233.6
RHOB
ras homolog family member B
chr22_-_46537593 0.16 ENST00000262738.9
ENST00000674500.2
CELSR1
cadherin EGF LAG seven-pass G-type receptor 1
chr17_-_76353851 0.16 ENST00000446526.8
PRPSAP1
phosphoribosyl pyrophosphate synthetase associated protein 1
chr7_+_98617275 0.15 ENST00000265634.4
NPTX2
neuronal pentraxin 2
chr3_+_98732236 0.15 ENST00000265261.10
ENST00000483910.5
ENST00000460774.5
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr22_-_28679865 0.15 ENST00000397906.6
TTC28
tetratricopeptide repeat domain 28
chr10_-_32056376 0.15 ENST00000302418.5
KIF5B
kinesin family member 5B
chr8_+_94823210 0.15 ENST00000521860.5
ENST00000523731.6
ENST00000519457.5
ENST00000519053.5
INTS8
integrator complex subunit 8
chr14_-_92106607 0.15 ENST00000340660.10
ENST00000393287.9
ENST00000429774.6
ENST00000545170.5
ENST00000620536.4
ENST00000621269.4
ATXN3
ataxin 3
chr10_+_110644306 0.14 ENST00000369519.4
RBM20
RNA binding motif protein 20
chr3_+_138347648 0.14 ENST00000614350.4
ENST00000289104.8
MRAS
muscle RAS oncogene homolog
chrX_+_71095838 0.14 ENST00000374259.8
FOXO4
forkhead box O4
chr3_-_197555950 0.13 ENST00000445160.2
ENST00000392379.6
ENST00000446746.5
ENST00000432819.5
ENST00000441275.5
ENST00000392378.6
BDH1
3-hydroxybutyrate dehydrogenase 1
chr1_-_154970735 0.13 ENST00000368445.9
ENST00000448116.7
ENST00000368449.8
SHC1
SHC adaptor protein 1
chr17_+_2796404 0.13 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chrX_-_10677720 0.13 ENST00000453318.6
MID1
midline 1
chr21_-_39313610 0.12 ENST00000342449.8
ENST00000341322.4
BRWD1
bromodomain and WD repeat domain containing 1
chrX_-_46759055 0.12 ENST00000328306.4
ENST00000616978.5
SLC9A7
solute carrier family 9 member A7
chr7_-_128031422 0.12 ENST00000249363.4
LRRC4
leucine rich repeat containing 4
chrX_+_12975083 0.12 ENST00000451311.7
ENST00000380636.1
TMSB4X
thymosin beta 4 X-linked
chr18_+_49562049 0.12 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
LIPG
lipase G, endothelial type
chr13_-_27620520 0.12 ENST00000316334.5
LNX2
ligand of numb-protein X 2
chr1_+_7771263 0.12 ENST00000054666.11
VAMP3
vesicle associated membrane protein 3
chr1_-_46668454 0.11 ENST00000576409.5
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr2_-_53970985 0.11 ENST00000404125.6
PSME4
proteasome activator subunit 4
chr9_-_137028223 0.11 ENST00000341511.11
ABCA2
ATP binding cassette subfamily A member 2
chr17_-_4366616 0.11 ENST00000572484.5
ENST00000396981.7
UBE2G1
ubiquitin conjugating enzyme E2 G1
chrX_+_71533095 0.11 ENST00000373719.8
ENST00000373701.7
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr1_+_27392612 0.11 ENST00000374024.4
GPR3
G protein-coupled receptor 3
chr20_-_51802509 0.11 ENST00000371539.7
ENST00000217086.9
SALL4
spalt like transcription factor 4
chr8_+_17156463 0.11 ENST00000262096.13
ZDHHC2
zinc finger DHHC-type palmitoyltransferase 2
chr6_-_107115493 0.11 ENST00000369042.6
BEND3
BEN domain containing 3
chr3_-_196503720 0.11 ENST00000318037.3
RNF168
ring finger protein 168
chr13_+_98142552 0.10 ENST00000595437.5
FARP1
FERM, ARH/RhoGEF and pleckstrin domain protein 1
chr1_-_44031446 0.10 ENST00000372310.8
ENST00000466926.1
SLC6A9
solute carrier family 6 member 9
chr14_-_53152371 0.10 ENST00000323669.10
DDHD1
DDHD domain containing 1
chrX_-_107716401 0.10 ENST00000486554.1
ENST00000372390.8
TSC22D3
TSC22 domain family member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.4 1.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.4 1.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.3 1.3 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.3 1.9 GO:0008218 bioluminescence(GO:0008218)
0.3 1.8 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.3 3.1 GO:0060352 cell adhesion molecule production(GO:0060352)
0.3 1.3 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.2 3.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 0.8 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 1.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 1.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.6 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 1.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 1.0 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.5 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 2.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.6 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.7 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 2.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.7 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.4 GO:0001927 exocyst assembly(GO:0001927)
0.1 2.7 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.6 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 2.9 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.8 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0018032 protein amidation(GO:0018032)
0.1 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:1902617 response to fluoride(GO:1902617)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.9 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1 0.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 1.8 GO:0097503 sialylation(GO:0097503)
0.1 1.2 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 1.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 0.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 1.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.9 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 1.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 1.1 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.4 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0048194 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) Golgi vesicle budding(GO:0048194)
0.0 1.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 1.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0046051 UTP metabolic process(GO:0046051)
0.0 0.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.4 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.6 GO:0016577 histone demethylation(GO:0016577)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.5 GO:0003016 respiratory system process(GO:0003016)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.3 0.9 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.2 0.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 3.4 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0098592 microspike(GO:0044393) cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.6 GO:0030057 desmosome(GO:0030057)
0.0 1.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 4.1 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0032116 SMC loading complex(GO:0032116)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.4 2.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 0.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 2.1 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.3 0.8 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 0.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 0.7 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 2.9 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 1.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.0 GO:0052846 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 0.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.8 GO:0035276 ethanol binding(GO:0035276)
0.1 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.1 1.2 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 1.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 4.0 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 1.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 3.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 4.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 5.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 3.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 3.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.8 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs