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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for VDR

Z-value: 0.80

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Transcription factors associated with VDR

Gene Symbol Gene ID Gene Info
ENSG00000111424.12 VDR

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VDRhg38_v1_chr12_-_47905003_479050430.491.2e-02Click!

Activity profile of VDR motif

Sorted Z-values of VDR motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VDR

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_74099187 2.10 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr1_+_61404076 1.69 ENST00000357977.5
nuclear factor I A
chr4_-_74038681 1.53 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr14_-_35404650 1.35 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr1_+_99646025 1.34 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr7_+_30911845 1.15 ENST00000652696.1
ENST00000311813.11
aquaporin 1 (Colton blood group)
chr16_-_30096170 1.13 ENST00000566134.5
ENST00000565110.5
ENST00000398841.6
ENST00000398838.8
yippee like 3
chr19_-_54189550 1.02 ENST00000338624.10
ENST00000245615.6
membrane bound O-acyltransferase domain containing 7
chr3_+_101849505 1.02 ENST00000326151.9
ENST00000326172.9
NFKB inhibitor zeta
chr7_+_155298561 0.98 ENST00000476756.1
insulin induced gene 1
chr3_+_37975773 0.97 ENST00000436654.1
CTD small phosphatase like
chr6_-_42048648 0.97 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr17_-_36264514 0.90 ENST00000618620.4
ENST00000621034.1
TBC1 domain family member 3I
chr10_+_30434176 0.86 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr17_-_38192555 0.85 ENST00000620215.3
TBC1 domain family member 3
chr6_+_142301926 0.85 ENST00000296932.13
ENST00000367609.8
adhesion G protein-coupled receptor G6
chr17_+_37924415 0.85 ENST00000620247.1
TBC1 domain family member 3K
chr17_-_38068634 0.85 ENST00000622206.2
TBC1 domain family member 3C
chr3_-_65622073 0.84 ENST00000621418.4
ENST00000611645.4
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr19_+_13150386 0.82 ENST00000292433.4
ENST00000587885.1
immediate early response 2
chr17_-_37989048 0.81 ENST00000617678.2
ENST00000612727.5
TBC1 domain family member 3L
chr10_+_35195843 0.80 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr17_+_36323884 0.80 ENST00000569055.2
TBC1 domain family member 3G
chr20_+_64063481 0.80 ENST00000415602.5
transcription elongation factor A2
chr17_+_38003976 0.80 ENST00000616101.4
TBC1 domain family member 3D
chr17_-_36439566 0.78 ENST00000620210.1
TBC1 domain family member 3F
chr3_-_27722699 0.74 ENST00000461503.2
eomesodermin
chrX_+_71910818 0.69 ENST00000633930.1
NHS like 2
chr7_+_155297776 0.68 ENST00000344756.8
ENST00000425172.1
ENST00000340368.9
ENST00000342407.5
insulin induced gene 1
chr13_-_52011337 0.67 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr18_+_44697118 0.67 ENST00000677077.1
SET binding protein 1
chr17_-_36388423 0.67 ENST00000610350.3
TBC1 domain family member 3H
chr10_-_102241502 0.64 ENST00000370002.8
paired like homeodomain 3
chr1_+_153778178 0.59 ENST00000532853.5
solute carrier family 27 member 3
chr14_+_100065400 0.59 ENST00000555706.5
ENST00000392920.8
ENST00000555048.5
Enah/Vasp-like
chr19_+_18419374 0.58 ENST00000270061.12
single stranded DNA binding protein 4
chr16_-_2720217 0.57 ENST00000302641.8
serine protease 27
chr8_-_92103217 0.54 ENST00000615601.4
ENST00000523629.5
RUNX1 partner transcriptional co-repressor 1
chr17_-_36176636 0.52 ENST00000611257.5
ENST00000616006.1
TBC1 domain family member 3B
chrX_-_135816265 0.52 ENST00000605791.7
cancer/testis antigen family 45 member A2
chr6_+_85449584 0.52 ENST00000369651.7
5'-nucleotidase ecto
chr1_+_92168915 0.52 ENST00000637221.2
BTB domain containing 8
chr10_-_33334625 0.52 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr5_+_134526100 0.51 ENST00000395003.5
jade family PHD finger 2
chr17_+_29568591 0.50 ENST00000581411.6
ENST00000301057.8
tumor protein p53 inducible protein 13
chr10_-_33334898 0.49 ENST00000395995.5
neuropilin 1
chr9_-_127854636 0.48 ENST00000344849.4
ENST00000373203.9
endoglin
chr12_-_25195074 0.47 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr19_+_57682019 0.45 ENST00000596085.1
ENST00000594684.1
zinc finger protein 551
novel protein
chr3_+_45030130 0.44 ENST00000428034.1
C-type lectin domain family 3 member B
chr17_+_38127951 0.44 ENST00000621587.2
TBC1 domain family member 3E
chr3_+_51977833 0.44 ENST00000637978.1
ABHD14A-ACY1 readthrough
chr12_+_79045625 0.42 ENST00000552744.5
synaptotagmin 1
chr1_+_33256479 0.41 ENST00000539719.6
ENST00000483388.5
zinc finger protein 362
chr1_-_221742074 0.39 ENST00000366899.4
dual specificity phosphatase 10
chr17_-_7261092 0.39 ENST00000574070.5
claudin 7
chr1_-_54053192 0.38 ENST00000371337.3
ENST00000234831.10
transmembrane protein 59
chr12_-_108827384 0.38 ENST00000326470.9
slingshot protein phosphatase 1
chr1_+_43991588 0.38 ENST00000372318.8
coiled-coil domain containing 24
chr9_+_128882502 0.38 ENST00000259324.5
leucine rich repeat containing 8 VRAC subunit A
chr3_-_27722316 0.37 ENST00000449599.4
eomesodermin
chr3_+_50155305 0.37 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr10_-_18651576 0.37 ENST00000377304.7
NOP2/Sun RNA methyltransferase 6
chr1_-_6490564 0.37 ENST00000377725.5
ENST00000340850.10
pleckstrin homology and RhoGEF domain containing G5
chr16_+_1078781 0.36 ENST00000293897.5
somatostatin receptor 5
chr6_+_35259703 0.36 ENST00000373953.8
ENST00000339411.5
zinc finger protein 76
chr11_+_925840 0.35 ENST00000448903.7
ENST00000525796.5
ENST00000534328.5
adaptor related protein complex 2 subunit alpha 2
chr2_+_176269406 0.35 ENST00000249442.11
ENST00000443241.5
metaxin 2
chr12_+_56128217 0.33 ENST00000267113.4
ENST00000394048.10
extended synaptotagmin 1
chr16_-_75248190 0.33 ENST00000542031.6
BCAR1 scaffold protein, Cas family member
chr3_+_50155024 0.33 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr3_+_48223325 0.33 ENST00000296435.2
cathelicidin antimicrobial peptide
chr19_+_49513353 0.33 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chrX_-_66033664 0.32 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr16_-_67183948 0.32 ENST00000561621.5
ENST00000563902.2
ENST00000290881.11
KIAA0895 like
chr11_+_7513966 0.31 ENST00000299492.9
PPFIA binding protein 2
chr8_-_143953845 0.31 ENST00000354958.6
plectin
chr10_-_33335074 0.30 ENST00000432372.6
neuropilin 1
chr18_-_48409292 0.30 ENST00000589194.5
ENST00000591279.5
ENST00000590855.5
ENST00000587107.5
ENST00000588970.5
ENST00000586525.5
ENST00000592387.5
ENST00000590800.6
zinc finger and BTB domain containing 7C
chr17_+_32927910 0.29 ENST00000394642.7
transmembrane protein 98
chr19_+_48619528 0.29 ENST00000598088.5
sphingosine kinase 2
chr11_+_124739927 0.29 ENST00000284292.11
ENST00000412681.2
neurogranin
chr16_+_15949549 0.28 ENST00000399408.7
ENST00000572882.3
ENST00000677164.1
ATP binding cassette subfamily C member 1
chr12_+_48482492 0.28 ENST00000548364.7
chromosome 12 open reading frame 54
chr19_+_48619489 0.28 ENST00000245222.9
sphingosine kinase 2
chr17_-_45410414 0.28 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr20_-_23568474 0.28 ENST00000376979.4
cystatin 9 like
chr16_+_590200 0.28 ENST00000563109.1
RAB40C, member RAS oncogene family
chr3_-_94062881 0.27 ENST00000619045.1
dihydrofolate reductase 2
chr11_-_61815106 0.27 ENST00000539419.5
ENST00000545245.5
ENST00000545405.5
ENST00000542506.5
fatty acid desaturase 1
chr11_-_790062 0.26 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr22_-_29267965 0.26 ENST00000216085.12
rhomboid domain containing 3
chr10_+_117542416 0.26 ENST00000442245.5
empty spiracles homeobox 2
chr6_+_125154189 0.25 ENST00000532429.5
ENST00000534199.5
TPD52 like 1
chr7_-_36724543 0.24 ENST00000612871.4
acyloxyacyl hydrolase
chr5_-_141673160 0.24 ENST00000513878.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr4_+_143513661 0.24 ENST00000283131.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_+_209653171 0.24 ENST00000447185.5
microtubule associated protein 2
chr17_-_7179544 0.23 ENST00000619926.4
asialoglycoprotein receptor 1
chr19_+_48619291 0.23 ENST00000340932.7
ENST00000601712.5
ENST00000600537.5
sphingosine kinase 2
chr1_-_54053394 0.23 ENST00000452421.5
ENST00000420738.5
ENST00000440019.5
transmembrane protein 59
chr7_-_36724457 0.23 ENST00000617537.5
ENST00000435386.1
acyloxyacyl hydrolase
chr7_-_36724380 0.22 ENST00000617267.4
acyloxyacyl hydrolase
chr6_+_29111560 0.22 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr2_+_38666059 0.22 ENST00000272252.10
ENST00000410063.5
galactose mutarotase
chr10_-_75235917 0.22 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr20_+_57329801 0.22 ENST00000371263.8
ENST00000345868.8
ENST00000371260.8
ENST00000418127.5
SPO11 initiator of meiotic double stranded breaks
chr17_-_76103690 0.22 ENST00000411744.6
ENST00000634349.1
ENST00000332065.9
ENST00000607838.5
exocyst complex component 7
chr19_+_13906255 0.22 ENST00000589606.5
coiled-coil and C2 domain containing 1A
chr15_+_41559189 0.22 ENST00000263798.8
TYRO3 protein tyrosine kinase
chr8_+_97887903 0.21 ENST00000520016.5
matrilin 2
chr2_+_229922482 0.21 ENST00000283946.8
ENST00000409992.1
F-box protein 36
chr6_+_38715288 0.21 ENST00000327475.11
dynein axonemal heavy chain 8
chr14_+_94581407 0.21 ENST00000553511.1
ENST00000329597.12
ENST00000554633.5
ENST00000555681.1
ENST00000554276.1
serpin family A member 5
chr19_+_7534711 0.21 ENST00000414982.7
ENST00000450331.7
patatin like phospholipase domain containing 6
chr17_-_76103714 0.20 ENST00000406660.4
ENST00000335146.11
ENST00000405575.8
ENST00000589210.6
exocyst complex component 7
chr20_+_31440626 0.20 ENST00000376309.4
defensin beta 123
chr16_+_67173971 0.19 ENST00000563258.1
ENST00000568146.1
nucleolar protein 3
chr3_-_94062906 0.19 ENST00000314636.3
ENST00000394221.3
dihydrofolate reductase 2
chr1_-_54053461 0.19 ENST00000371341.5
transmembrane protein 59
chr1_-_156082412 0.19 ENST00000532414.3
mex-3 RNA binding family member A
chr6_-_116765709 0.18 ENST00000368557.6
family with sequence similarity 162 member B
chr16_+_15949597 0.18 ENST00000399410.8
ATP binding cassette subfamily C member 1
chr2_+_108288639 0.18 ENST00000326853.9
sulfotransferase family 1C member 2
chrX_-_56995426 0.18 ENST00000640768.1
ENST00000638619.1
spindlin family member 3
chr2_+_169069537 0.18 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr1_+_154502207 0.18 ENST00000368482.8
tudor domain containing 10
chrX_+_154542194 0.17 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr6_-_30556477 0.17 ENST00000376621.8
G protein nucleolar 1 (putative)
chr3_+_10992175 0.17 ENST00000646702.1
solute carrier family 6 member 1
chr2_-_88861258 0.17 ENST00000390240.2
immunoglobulin kappa joining 3
chr6_+_30557287 0.17 ENST00000376560.8
proline rich 3
chr10_+_102394488 0.17 ENST00000369966.8
nuclear factor kappa B subunit 2
chr4_-_36244438 0.16 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_30557274 0.16 ENST00000376557.3
proline rich 3
chr19_+_54966343 0.16 ENST00000537859.5
ENST00000585500.5
ENST00000427260.6
ENST00000448584.7
ENST00000263437.10
NLR family pyrin domain containing 2
chr11_+_64230726 0.16 ENST00000321460.5
DnaJ heat shock protein family (Hsp40) member C4
chr19_+_36140967 0.16 ENST00000588780.5
ENST00000629983.2
calpain small subunit 1
chr16_-_87765899 0.16 ENST00000353170.9
ENST00000561825.1
ENST00000562261.1
ENST00000347925.9
ENST00000270583.10
ENST00000622456.4
kelch domain containing 4
chr19_-_54222978 0.16 ENST00000245620.13
ENST00000346401.10
ENST00000445347.1
leukocyte immunoglobulin like receptor B3
chr1_-_183590596 0.16 ENST00000418089.5
ENST00000413720.5
neutrophil cytosolic factor 2
chr19_-_47484176 0.16 ENST00000595554.1
ENST00000338134.8
ENST00000600271.5
kaptin, actin binding protein
chr1_-_205357033 0.16 ENST00000367156.7
ENST00000606887.5
ENST00000539253.5
ENST00000607173.5
kelch domain containing 8A
chr1_+_51617079 0.16 ENST00000447887.5
ENST00000428468.6
ENST00000453295.5
oxysterol binding protein like 9
chr1_-_183590439 0.15 ENST00000367535.8
neutrophil cytosolic factor 2
chr13_+_112968496 0.15 ENST00000397030.5
MCF.2 cell line derived transforming sequence like
chr19_-_5903703 0.15 ENST00000586349.5
ENST00000585661.1
ENST00000592634.5
ENST00000418389.6
ENST00000308961.5
novel protein
NADH:ubiquinone oxidoreductase subunit A11
chr22_+_22711689 0.15 ENST00000390308.2
immunoglobulin lambda variable 3-21
chr15_-_72271244 0.15 ENST00000287196.13
poly(ADP-ribose) polymerase family member 6
chr3_+_54123452 0.14 ENST00000620722.4
ENST00000490478.5
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr1_+_26021768 0.14 ENST00000374280.4
exostosin like glycosyltransferase 1
chr21_-_33931607 0.14 ENST00000429238.2
novel protein similar to ATP synthase delta (OSCP) subunit domain
chr10_-_5499544 0.14 ENST00000380332.5
calmodulin like 5
chr12_-_113966306 0.14 ENST00000545145.6
ENST00000392561.7
ENST00000261741.10
RNA binding motif protein 19
chr3_+_13480215 0.14 ENST00000446613.6
ENST00000402259.5
ENST00000402271.5
ENST00000295757.8
ENST00000404548.5
ENST00000404040.5
histone deacetylase 11
chr19_+_54190268 0.14 ENST00000429671.7
ENST00000302937.8
ENST00000667261.1
tRNA splicing endonuclease subunit 34
chr19_-_12723925 0.14 ENST00000425528.6
ENST00000589337.5
ENST00000588216.5
transportin 2
chrX_-_56995508 0.13 ENST00000374919.6
ENST00000639007.1
ENST00000639583.1
ENST00000638289.1
ENST00000639525.1
ENST00000638386.1
spindlin family member 3
chr1_-_175023408 0.13 ENST00000476371.1
mitochondrial ribosomal protein S14
chr16_+_31108294 0.13 ENST00000287507.7
ENST00000394950.7
ENST00000219794.11
ENST00000561755.1
branched chain keto acid dehydrogenase kinase
chr13_+_113001707 0.13 ENST00000375604.6
MCF.2 cell line derived transforming sequence like
chr16_-_67150951 0.13 ENST00000449549.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr13_+_113667213 0.13 ENST00000335678.7
G protein-coupled receptor kinase 1
chr5_-_179800540 0.13 ENST00000520875.5
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
chr16_-_50681206 0.13 ENST00000610485.1
sorting nexin 20
chr16_+_67173935 0.13 ENST00000566871.5
nucleolar protein 3
chr11_+_61102465 0.13 ENST00000347785.8
ENST00000544014.1
CD5 molecule
chr17_+_80415159 0.13 ENST00000520367.5
ENST00000518137.6
ENST00000523999.5
ENST00000323854.9
ENST00000522751.5
endonuclease V
chr2_+_108288869 0.13 ENST00000251481.11
ENST00000438339.5
ENST00000409880.5
ENST00000437390.6
sulfotransferase family 1C member 2
chr5_+_134526176 0.12 ENST00000681820.1
ENST00000512386.6
ENST00000612830.2
jade family PHD finger 2
chr8_+_74824526 0.12 ENST00000649643.1
ENST00000260113.7
peptidase inhibitor 15
chr16_-_68371005 0.12 ENST00000574662.1
sphingomyelin phosphodiesterase 3
chr12_+_52301833 0.12 ENST00000293525.5
keratin 86
chr7_+_100101657 0.12 ENST00000421755.5
adaptor related protein complex 4 subunit mu 1
chrX_+_151563662 0.12 ENST00000370357.5
PAS domain containing repressor 1
chr9_+_128276222 0.12 ENST00000608796.6
ENST00000419867.7
ENST00000418976.2
SWI5 homologous recombination repair protein
chr11_-_74170975 0.12 ENST00000539061.6
ENST00000680645.1
ENST00000334126.12
ENST00000680718.1
C2 domain containing 3 centriole elongation regulator
chr4_-_151760977 0.11 ENST00000512306.5
ENST00000508611.1
ENST00000515812.5
ENST00000263985.11
glutamyl-tRNA amidotransferase subunit B
chr12_+_53461015 0.11 ENST00000553064.6
ENST00000547859.2
poly(rC) binding protein 2
chr5_-_147831627 0.11 ENST00000510027.2
serine peptidase inhibitor Kazal type 1
chr15_+_75647877 0.11 ENST00000308527.6
sorting nexin 33
chr14_+_104745960 0.11 ENST00000556623.1
ENST00000555674.1
adenylosuccinate synthase 1
chr1_-_205356894 0.10 ENST00000367155.8
kelch domain containing 8A
chr6_+_13574227 0.10 ENST00000680432.1
ENST00000681012.1
ENST00000397350.7
sirtuin 5
chr12_+_54284258 0.10 ENST00000677666.1
heterogeneous nuclear ribonucleoprotein A1
chr7_-_100428657 0.10 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chrX_-_154516183 0.10 ENST00000442929.1
ENST00000426266.5
ENST00000447601.7
ENST00000359889.9
ENST00000369641.7
ENST00000322269.10
ENST00000419205.5
FAM3 metabolism regulating signaling molecule A
chr13_-_52739769 0.10 ENST00000448904.6
ENST00000377962.8
chondromodulin
chr16_-_31094727 0.10 ENST00000300851.10
ENST00000394975.3
vitamin K epoxide reductase complex subunit 1
chr16_-_67247460 0.10 ENST00000258201.9
formin homology 2 domain containing 1
chr17_-_78782257 0.10 ENST00000591455.5
ENST00000446868.7
ENST00000361101.8
ENST00000589296.5
cytohesin 1
chr19_+_1383891 0.10 ENST00000539480.5
ENST00000313408.11
ENST00000233627.14
ENST00000620479.4
ENST00000414651.3
NADH:ubiquinone oxidoreductase core subunit S7
chr14_+_94581388 0.10 ENST00000554866.5
ENST00000556775.5
serpin family A member 5
chr15_-_58933668 0.09 ENST00000380516.7
SAFB like transcription modulator
chr8_+_24440930 0.09 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM metallopeptidase domain 7
chr15_+_75201873 0.09 ENST00000394987.5
chromosome 15 open reading frame 39
chr9_+_136945234 0.09 ENST00000371634.7
complement C8 gamma chain
chr11_-_6603571 0.09 ENST00000534343.1
ENST00000254605.11
ribosomal RNA processing 8
chrY_-_6872608 0.09 ENST00000383036.1
amelogenin Y-linked
chrX_+_21374608 0.09 ENST00000644295.1
ENST00000645074.1
ENST00000645791.1
ENST00000643220.1
connector enhancer of kinase suppressor of Ras 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 1.2 GO:0071288 nitric oxide transport(GO:0030185) cerebrospinal fluid secretion(GO:0033326) cellular response to mercury ion(GO:0071288) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.4 1.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 1.3 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3 0.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.7 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.7 GO:0060003 copper ion export(GO:0060003)
0.2 0.6 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.2 0.8 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 1.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.5 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 3.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.3 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.1 0.5 GO:0046086 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.1 0.2 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.4 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 8.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.3 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.2 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.1 0.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.2 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 1.0 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.7 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.5 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0061699 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 1.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.2 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0035732 nitric oxide storage(GO:0035732)
0.0 0.1 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.0 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.3 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.0 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 1.2 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.2 0.5 GO:0072563 endothelial microparticle(GO:0072563)
0.1 1.3 GO:0097443 sorting endosome(GO:0097443)
0.1 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0036027 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 1.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.7 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.2 1.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.8 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.1 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 1.0 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0036055 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.0 8.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0089720 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.1 GO:0052831 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.0 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.0 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 3.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis