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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for XBP1

Z-value: 1.68

Motif logo

Transcription factors associated with XBP1

Gene Symbol Gene ID Gene Info
ENSG00000100219.16 XBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
XBP1hg38_v1_chr22_-_28800558_288005970.367.9e-02Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_128052166 9.52 ENST00000648300.1
monoglyceride lipase
chr5_-_122078249 6.27 ENST00000231004.5
lysyl oxidase
chr9_+_35732649 6.06 ENST00000353704.3
cAMP responsive element binding protein 3
chr19_+_49527988 4.94 ENST00000270645.8
reticulocalbin 3
chr8_+_103372388 4.16 ENST00000520337.1
collagen triple helix repeat containing 1
chr2_-_69387130 3.78 ENST00000674438.1
glutamine--fructose-6-phosphate transaminase 1
chr6_+_116370938 3.53 ENST00000644252.3
ENST00000646710.1
ENST00000359564.3
dermatan sulfate epimerase
chr5_+_127517611 3.48 ENST00000296666.13
ENST00000442138.6
ENST00000512635.2
proline rich coiled-coil 1
chr20_-_63568074 3.32 ENST00000427522.6
helicase with zinc finger 2
chr3_+_105367212 3.26 ENST00000472644.6
activated leukocyte cell adhesion molecule
chr2_-_69387188 3.03 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr22_-_31107517 3.00 ENST00000400299.6
ENST00000611680.1
selenoprotein M
chr2_-_69387241 2.84 ENST00000361060.5
glutamine--fructose-6-phosphate transaminase 1
chr21_-_17612842 2.82 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chr11_-_64878612 2.81 ENST00000320631.8
EH domain containing 1
chr1_-_11060000 2.78 ENST00000376957.7
spermidine synthase
chr6_-_83193207 2.52 ENST00000652468.1
ENST00000512866.5
ENST00000616566.5
ENST00000510258.1
ENST00000650642.1
ENST00000513973.6
ENST00000503094.1
ENST00000283977.9
ENST00000509219.2
ENST00000651425.1
ENST00000508748.5
phosphoglucomutase 3
chr8_-_63026179 2.43 ENST00000677919.1
gamma-glutamyl hydrolase
chrX_+_9463272 2.34 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr11_-_207221 2.29 ENST00000486280.1
ENST00000332865.10
ENST00000529614.6
ENST00000325147.13
ENST00000410108.5
ENST00000382762.7
Bet1 golgi vesicular membrane trafficking protein like
chr5_-_9546066 2.13 ENST00000382496.10
ENST00000652226.1
semaphorin 5A
chr6_+_83193331 2.00 ENST00000369724.5
RWD domain containing 2A
chr1_+_148952341 1.96 ENST00000529945.2
phosphodiesterase 4D interacting protein
chr1_+_148952120 1.95 ENST00000313431.13
phosphodiesterase 4D interacting protein
chr12_+_106955719 1.94 ENST00000548125.5
transmembrane protein 263
chr4_+_128061336 1.91 ENST00000432347.6
La ribonucleoprotein 1B
chr12_-_121274510 1.88 ENST00000392474.6
calcium/calmodulin dependent protein kinase kinase 2
chr6_+_33200860 1.85 ENST00000374677.8
solute carrier family 39 member 7
chr6_+_33200820 1.84 ENST00000374675.7
solute carrier family 39 member 7
chr19_-_10333512 1.84 ENST00000617231.5
ENST00000611074.4
ENST00000615032.4
ribonucleoprotein, PTB binding 1
chr13_+_45464901 1.84 ENST00000349995.10
component of oligomeric golgi complex 3
chr4_-_118836067 1.83 ENST00000280551.11
SEC24 homolog D, COPII coat complex component
chr19_+_17075767 1.79 ENST00000682292.1
ENST00000595618.5
ENST00000594824.5
myosin IXB
chr6_-_89352706 1.75 ENST00000435041.3
ubiquitin conjugating enzyme E2 J1
chr13_+_45464995 1.75 ENST00000617493.1
component of oligomeric golgi complex 3
chr15_-_83284645 1.74 ENST00000345382.7
basonuclin 1
chr3_+_128052390 1.72 ENST00000481210.5
ENST00000243253.8
SEC61 translocon subunit alpha 1
chr1_+_26432299 1.72 ENST00000427245.6
ENST00000236342.12
ENST00000525682.6
ENST00000526219.5
ENST00000374185.7
ENST00000360009.6
ENST00000533087.5
ENST00000531312.5
ENST00000525165.5
ENST00000525326.5
ENST00000525546.5
ENST00000436153.6
ENST00000530781.5
dehydrodolichyl diphosphate synthase subunit
chr20_+_34363241 1.70 ENST00000486883.5
ENST00000374864.10
ENST00000535650.7
ENST00000670516.1
ENST00000665484.1
ENST00000654846.1
ENST00000665428.1
ENST00000660337.1
ENST00000262650.10
ENST00000665346.1
itchy E3 ubiquitin protein ligase
chr11_+_207688 1.66 ENST00000526104.6
RIC8 guanine nucleotide exchange factor A
chr1_-_204494752 1.65 ENST00000684373.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr3_-_57597443 1.65 ENST00000463880.1
ADP ribosylation factor 4
chr20_-_17682060 1.63 ENST00000455029.3
ribosome binding protein 1
chr6_-_43629222 1.62 ENST00000307126.10
GTP binding protein 2
chr14_+_49620750 1.57 ENST00000305386.4
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr21_+_43719095 1.56 ENST00000468090.5
ENST00000291565.9
pyridoxal kinase
chr17_+_8435871 1.52 ENST00000334527.12
ENST00000585098.5
ENST00000380025.8
ENST00000402554.7
ENST00000584866.1
ENST00000582490.5
nudE neurodevelopment protein 1 like 1
chr3_-_156555083 1.51 ENST00000265044.7
ENST00000476217.5
signal sequence receptor subunit 3
chr11_-_62832033 1.44 ENST00000377897.8
ENST00000394690.5
ENST00000294179.8
syntaxin 5
chr5_+_177303768 1.43 ENST00000303204.9
ENST00000503216.5
PRELI domain containing 1
chr20_-_8019744 1.43 ENST00000246024.7
thioredoxin related transmembrane protein 4
chr2_+_27032938 1.42 ENST00000238788.14
ENST00000404032.7
transmembrane protein 214
chr2_-_33599269 1.40 ENST00000431950.1
ENST00000403368.1
ENST00000238823.13
family with sequence similarity 98 member A
chr11_-_59615673 1.39 ENST00000263847.6
oxysterol binding protein
chr19_-_48511793 1.39 ENST00000600059.6
lemur tyrosine kinase 3
chr17_-_15563428 1.34 ENST00000584811.5
ENST00000419890.3
ENST00000518321.6
ENST00000438826.7
ENST00000225576.7
ENST00000428082.6
ENST00000522212.6
trans-golgi network vesicle protein 23 homolog C
TVP23C-CDRT4 readthrough
chr6_+_138161932 1.33 ENST00000251691.5
ARFGEF family member 3
chr3_+_172040554 1.32 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr22_+_38468036 1.31 ENST00000409006.3
ENST00000216014.9
KDEL endoplasmic reticulum protein retention receptor 3
chr2_+_64454145 1.25 ENST00000238875.10
galectin like
chr2_+_170929198 1.24 ENST00000234160.5
golgi reassembly stacking protein 2
chr19_-_10315737 1.22 ENST00000492239.5
ferredoxin 2
chr10_+_87659839 1.22 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr3_+_133805789 1.19 ENST00000678299.1
SRP receptor subunit beta
chr9_+_111631300 1.18 ENST00000313525.4
DnaJ heat shock protein family (Hsp40) member C25
chr9_-_35072588 1.18 ENST00000677257.1
ENST00000679862.1
ENST00000679902.1
ENST00000358901.11
ENST00000681335.1
ENST00000681386.1
ENST00000679647.1
ENST00000448530.6
valosin containing protein
chr19_-_10315987 1.18 ENST00000393708.3
ENST00000494368.5
ferredoxin 2
chr9_-_35072561 1.16 ENST00000678650.1
valosin containing protein
chr22_-_42857194 1.16 ENST00000437119.6
ENST00000454099.5
ENST00000263245.10
ADP ribosylation factor GTPase activating protein 3
chr4_-_47914596 1.15 ENST00000381538.7
ENST00000329043.7
nuclear transcription factor, X-box binding like 1
chr7_+_73433761 1.14 ENST00000344575.5
frizzled class receptor 9
chr8_-_123042244 1.12 ENST00000259512.9
ENST00000419562.6
derlin 1
chr2_-_118014035 1.11 ENST00000376300.7
coiled-coil domain containing 93
chr3_-_57597325 1.10 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ADP ribosylation factor 4
chr4_-_47914569 1.10 ENST00000507489.2
nuclear transcription factor, X-box binding like 1
chr7_-_30026617 1.08 ENST00000222803.10
FKBP prolyl isomerase 14
chr11_-_66289125 1.06 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
Yip1 interacting factor homolog A, membrane trafficking protein
chr5_-_10761156 1.06 ENST00000432074.2
ENST00000230895.11
death associated protein
chr2_-_118014125 1.05 ENST00000319432.9
coiled-coil domain containing 93
chr1_+_109090726 0.98 ENST00000338272.9
ENST00000651489.1
transmembrane protein 167B
chr20_-_17682234 0.98 ENST00000377813.6
ENST00000377807.6
ENST00000360807.8
ENST00000398782.2
ribosome binding protein 1
chr5_+_112861188 0.98 ENST00000503445.5
ENST00000505459.6
ENST00000282999.7
ENST00000391338.3
ENST00000515463.1
ENST00000621420.5
ENST00000445150.3
signal recognition particle 19
chr3_-_128650800 0.95 ENST00000296255.8
ribophorin I
chr19_-_57947675 0.95 ENST00000598928.1
ENST00000282308.4
zinc finger protein 256
chr8_+_55102448 0.93 ENST00000622811.1
XK related 4
chr5_-_177303675 0.93 ENST00000393611.6
ENST00000303270.6
ENST00000303251.11
RAB24, member RAS oncogene family
chr11_+_66052331 0.92 ENST00000528302.5
ENST00000322535.11
ENST00000524627.5
ENST00000533595.5
ENST00000530322.5
splicing factor 3b subunit 2
chr13_-_52739769 0.91 ENST00000448904.6
ENST00000377962.8
chondromodulin
chr11_-_93543382 0.90 ENST00000298966.7
single-pass membrane protein with coiled-coil domains 4
chr11_-_66289007 0.90 ENST00000431556.6
ENST00000528575.1
Yip1 interacting factor homolog A, membrane trafficking protein
chr14_+_101964561 0.90 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
dynein cytoplasmic 1 heavy chain 1
chr19_-_4670331 0.90 ENST00000262947.8
ENST00000599630.1
myeloid derived growth factor
chr5_-_2751670 0.90 ENST00000302057.6
iroquois homeobox 2
chr2_-_99336306 0.86 ENST00000264255.8
ENST00000409434.5
ENST00000434323.5
thioredoxin domain containing 9
chr10_-_22003678 0.86 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr19_+_38930916 0.86 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
mitochondrial ribosomal protein S12
chr12_-_132828823 0.80 ENST00000545875.4
ENST00000456883.6
ENST00000450791.7
ENST00000204726.8
golgin A3
chr4_-_158723355 0.79 ENST00000307720.4
peptidylprolyl isomerase D
chr8_-_123042122 0.77 ENST00000405944.7
derlin 1
chr17_-_76072486 0.77 ENST00000629930.1
ENST00000539137.5
ENST00000307877.7
signal recognition particle 68
chr2_+_64453969 0.75 ENST00000464281.5
galectin like
chr19_-_18919348 0.74 ENST00000349893.8
ENST00000351079.8
ENST00000600932.5
ENST00000262812.9
COPI coat complex subunit epsilon
chr6_-_107958165 0.71 ENST00000369002.9
SEC63 homolog, protein translocation regulator
chr3_-_10321041 0.71 ENST00000397109.7
ENST00000428626.5
ENST00000445064.1
ENST00000431352.1
ENST00000397117.5
ENST00000337354.8
ENST00000383801.6
ENST00000432213.1
ENST00000350697.8
SEC13 homolog, nuclear pore and COPII coat complex component
chr19_-_8005590 0.71 ENST00000407627.7
ENST00000593807.1
ELAV like RNA binding protein 1
chr20_+_58891981 0.70 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS complex locus
chr14_-_24195570 0.69 ENST00000530468.5
ENST00000528010.1
ENST00000396854.8
ENST00000524835.5
ENST00000525592.1
transmembrane 9 superfamily member 1
chr9_-_34522968 0.69 ENST00000399775.3
energy homeostasis associated
chr16_+_2429427 0.69 ENST00000397066.9
cyclin F
chr16_-_66925526 0.68 ENST00000299759.11
ENST00000420652.5
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr2_-_241315652 0.65 ENST00000310931.10
ENST00000413241.5
ENST00000423693.5
ENST00000428482.5
ENST00000420451.5
ENST00000417540.5
high density lipoprotein binding protein
chr22_-_30326923 0.64 ENST00000215790.12
TBC1 domain family member 10A
chr22_-_30326877 0.63 ENST00000403477.7
TBC1 domain family member 10A
chr19_+_18919688 0.62 ENST00000247003.9
DEAD-box helicase 49
chr10_-_70170466 0.62 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
secretion associated Ras related GTPase 1A
chr20_+_50958805 0.62 ENST00000244051.3
molybdenum cofactor synthesis 3
chr4_-_75724386 0.62 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP stress granule assembly factor 2
chr11_-_119057218 0.60 ENST00000652093.1
hypoxia up-regulated 1
chr20_+_32819942 0.60 ENST00000375571.6
microtubule associated protein RP/EB family member 1
chr4_-_82429402 0.58 ENST00000602300.5
heterogeneous nuclear ribonucleoprotein D like
chr2_-_88627365 0.58 ENST00000303236.9
eukaryotic translation initiation factor 2 alpha kinase 3
chr16_-_67968553 0.58 ENST00000576616.5
ENST00000572037.5
ENST00000316341.8
ENST00000422611.6
solute carrier family 12 member 4
chr4_-_75724362 0.57 ENST00000677583.1
G3BP stress granule assembly factor 2
chr14_-_24195334 0.57 ENST00000530563.1
ENST00000528895.5
ENST00000528669.5
ENST00000532632.1
ENST00000261789.9
transmembrane 9 superfamily member 1
chr15_+_79311137 0.56 ENST00000424155.6
ENST00000536821.5
transmembrane p24 trafficking protein 3
chr19_+_32691783 0.56 ENST00000397061.4
nudix hydrolase 19
chr1_-_27914513 0.55 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr11_-_119057185 0.55 ENST00000614668.4
ENST00000617285.5
hypoxia up-regulated 1
chr15_+_79311084 0.54 ENST00000299705.10
transmembrane p24 trafficking protein 3
chr5_-_109409938 0.53 ENST00000361189.7
praja ring finger ubiquitin ligase 2
chr17_+_66302606 0.52 ENST00000413366.8
protein kinase C alpha
chr20_+_45791978 0.52 ENST00000449078.5
ENST00000456939.5
deoxynucleotidyltransferase terminal interacting protein 1
chr10_-_126388455 0.50 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM metallopeptidase domain 12
chr9_-_109498251 0.50 ENST00000374541.4
ENST00000262539.7
protein tyrosine phosphatase non-receptor type 3
chr12_-_106247950 0.49 ENST00000378026.5
cytoskeleton associated protein 4
chr4_+_128061500 0.49 ENST00000649983.1
ENST00000648358.1
ENST00000650359.1
La ribonucleoprotein 1B
chr20_-_46364385 0.49 ENST00000243896.6
ENST00000543605.5
ENST00000372230.10
ENST00000317734.12
solute carrier family 35 member C2
chr11_-_119057105 0.48 ENST00000534233.5
ENST00000614711.4
ENST00000530467.5
ENST00000621959.4
ENST00000532519.6
ENST00000532421.5
ENST00000610597.1
ENST00000612687.4
hypoxia up-regulated 1
chr3_+_50246888 0.48 ENST00000451956.1
G protein subunit alpha i2
chrX_+_1591590 0.48 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr7_-_128405930 0.46 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
inosine monophosphate dehydrogenase 1
chr2_+_219544002 0.46 ENST00000421791.1
ENST00000373883.4
ENST00000451952.1
transmembrane protein 198
chr19_-_4066892 0.46 ENST00000322357.9
zinc finger and BTB domain containing 7A
chr20_+_45791930 0.45 ENST00000372622.8
deoxynucleotidyltransferase terminal interacting protein 1
chr1_-_145859061 0.43 ENST00000393045.7
protein inhibitor of activated STAT 3
chr9_+_124015397 0.42 ENST00000488674.2
LIM homeobox 2
chr18_+_36829111 0.42 ENST00000280020.10
ENST00000592521.5
ENST00000587139.5
KIAA1328
chr5_+_115841878 0.41 ENST00000316788.12
adaptor related protein complex 3 subunit sigma 1
chr1_-_145859043 0.41 ENST00000369298.5
protein inhibitor of activated STAT 3
chr4_-_46390039 0.39 ENST00000540012.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr7_-_6484057 0.39 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr12_-_98644733 0.37 ENST00000299157.5
ENST00000393042.3
IKBKB interacting protein
chr9_+_99222258 0.37 ENST00000223641.5
SEC61 translocon subunit beta
chr15_-_74873310 0.36 ENST00000562363.5
ENST00000564529.1
ENST00000268099.13
secretory carrier membrane protein 2
chr2_-_241315180 0.36 ENST00000441124.5
ENST00000391976.6
high density lipoprotein binding protein
chr10_+_102918344 0.36 ENST00000433628.2
cyclin and CBS domain divalent metal cation transport mediator 2
chr19_+_16077006 0.35 ENST00000586833.7
ENST00000642221.1
tropomyosin 4
chr14_+_69484722 0.34 ENST00000322564.9
pleckstrin homology and coiled-coil domain containing D1
chr10_+_63133279 0.34 ENST00000277746.11
nuclear receptor binding factor 2
chr8_+_97644164 0.33 ENST00000336273.8
metadherin
chr12_-_27970047 0.33 ENST00000395868.7
parathyroid hormone like hormone
chr1_+_6785437 0.32 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
calmodulin binding transcription activator 1
chr1_+_109984756 0.32 ENST00000393614.8
ENST00000369799.10
adenosylhomocysteinase like 1
chr10_+_102918276 0.31 ENST00000369878.9
ENST00000369875.3
cyclin and CBS domain divalent metal cation transport mediator 2
chr1_+_207496268 0.31 ENST00000529814.1
complement C3b/C4b receptor 1 (Knops blood group)
chr6_+_131808011 0.31 ENST00000647893.1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr16_-_75536071 0.30 ENST00000336257.8
carbohydrate sulfotransferase 5
chr15_-_90102448 0.30 ENST00000330062.8
ENST00000559482.5
isocitrate dehydrogenase (NADP(+)) 2
chr11_+_118572373 0.30 ENST00000392859.7
ENST00000264028.5
ENST00000614498.4
ENST00000359415.8
ENST00000534182.2
archain 1
chr22_+_19131271 0.29 ENST00000399635.4
testis specific serine kinase 2
chr5_+_120464236 0.28 ENST00000407149.7
ENST00000379551.2
proline rich 16
chr11_+_47408582 0.26 ENST00000531974.5
ENST00000362021.9
ENST00000531419.5
ENST00000531865.5
ENST00000354884.8
solute carrier family 39 member 13
chr17_+_38870050 0.26 ENST00000318008.11
ENST00000435347.7
LIM and SH3 protein 1
chr8_-_113436883 0.23 ENST00000455883.2
ENST00000297405.10
CUB and Sushi multiple domains 3
chr3_-_156555135 0.23 ENST00000467789.5
signal sequence receptor subunit 3
chr12_-_27970273 0.23 ENST00000542963.1
ENST00000535992.5
parathyroid hormone like hormone
chr1_+_207496229 0.23 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
complement C3b/C4b receptor 1 (Knops blood group)
chr2_+_241315223 0.22 ENST00000428282.5
ENST00000360051.7
septin 2
chr11_-_68271896 0.22 ENST00000533310.5
ENST00000304271.11
ENST00000527280.1
chromosome 11 open reading frame 24
chr1_+_236686454 0.22 ENST00000542672.6
ENST00000366578.6
ENST00000682015.1
ENST00000651275.1
actinin alpha 2
chrX_-_153794356 0.21 ENST00000427365.6
ENST00000444450.5
ENST00000217901.10
ENST00000370093.5
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
chr4_+_75724569 0.21 ENST00000514213.7
ENST00000264904.8
USO1 vesicle transport factor
chr5_-_61162352 0.20 ENST00000339020.8
ENST00000507416.1
small integral membrane protein 15
chr7_+_128739292 0.20 ENST00000535011.6
ENST00000542996.6
ENST00000249364.9
ENST00000449187.6
calumenin
chr19_+_36115439 0.20 ENST00000629269.2
ENST00000221855.8
ENST00000651435.1
ENST00000589996.5
ENST00000591296.1
tubulin folding cofactor B
chr8_+_104223344 0.19 ENST00000523362.5
regulating synaptic membrane exocytosis 2
chr4_+_127730386 0.19 ENST00000281154.6
solute carrier family 25 member 31
chr14_+_39267055 0.19 ENST00000396158.6
ENST00000280083.7
ENST00000341502.9
MIA SH3 domain ER export factor 2
chr4_-_46390100 0.18 ENST00000381620.9
gamma-aminobutyric acid type A receptor subunit alpha2
chr3_-_177196451 0.18 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chr2_+_241315092 0.18 ENST00000391973.6
septin 2
chr8_-_38269157 0.17 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
phospholipid phosphatase 5
chrX_+_47190836 0.17 ENST00000377351.8
ubiquitin like modifier activating enzyme 1
chr19_+_49850687 0.17 ENST00000594151.5
ENST00000600603.5
ENST00000601638.5
PTOV1 extended AT-hook containing adaptor protein
chr6_-_106325616 0.15 ENST00000360666.6
autophagy related 5
chr3_+_184315347 0.15 ENST00000424196.5
eukaryotic translation initiation factor 4 gamma 1
chr16_-_11797208 0.14 ENST00000571198.5
ENST00000572781.5
ENST00000355758.9
zinc finger CCCH-type containing 7A
chr5_-_35230467 0.13 ENST00000515839.1
ENST00000618457.5
prolactin receptor
chr11_-_119101814 0.12 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr2_+_84905644 0.11 ENST00000233143.6
thymosin beta 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.9 6.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.8 2.3 GO:1903004 flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.7 12.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.6 0.6 GO:0018307 enzyme active site formation(GO:0018307)
0.6 2.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.6 4.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.6 1.7 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.5 6.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 1.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 1.6 GO:1903382 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.4 1.2 GO:0000103 sulfate assimilation(GO:0000103)
0.4 2.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.4 2.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.4 1.6 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.4 1.1 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.4 3.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 3.0 GO:0035934 corticosterone secretion(GO:0035934)
0.3 1.9 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 1.9 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.3 2.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 1.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2 1.4 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 0.9 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.2 0.6 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 1.4 GO:0090166 Golgi disassembly(GO:0090166)
0.2 0.5 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.2 2.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 0.9 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 3.3 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.8 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.5 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.6 GO:1990737 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 1.8 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 3.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.9 GO:0090235 minus-end-directed organelle transport along microtubule(GO:0072385) regulation of metaphase plate congression(GO:0090235)
0.1 1.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 1.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 3.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 8.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 2.4 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 1.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.4 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.0 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.8 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 4.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.7 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 1.3 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.7 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 2.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.4 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.6 GO:0002076 osteoblast development(GO:0002076) negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0007616 long-term memory(GO:0007616)
0.0 1.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.5 2.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4 1.9 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.3 4.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 3.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 1.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.5 GO:0043203 axon hillock(GO:0043203)
0.1 1.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 3.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 4.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 5.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 25.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 2.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.9 GO:0030016 myofibril(GO:0030016)
0.0 2.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0030658 transport vesicle membrane(GO:0030658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.7 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
1.0 6.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.9 2.8 GO:0004766 spermidine synthase activity(GO:0004766)
0.9 3.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.6 1.7 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.5 2.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.5 9.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 1.6 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.4 2.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 2.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 2.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 6.1 GO:0035497 cAMP response element binding(GO:0035497)
0.2 1.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.8 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.5 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.2 1.7 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.5 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 5.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.6 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.0 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 4.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 3.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.4 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 3.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 3.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 4.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 2.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.6 GO:0051087 chaperone binding(GO:0051087)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 1.4 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 4.9 GO:0005525 GTP binding(GO:0005525)
0.0 2.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 5.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 6.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 2.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 3.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 3.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 2.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis