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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZBTB18

Z-value: 0.61

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Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ZBTB18
ENSG00000179456.10 ZBTB18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB18hg38_v1_chr1_+_244051275_244051291-0.271.9e-01Click!

Activity profile of ZBTB18 motif

Sorted Z-values of ZBTB18 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_119354771 1.25 ENST00000503646.1
TNFAIP8
TNF alpha induced protein 8
chr17_+_34270213 1.04 ENST00000378569.2
ENST00000394627.5
ENST00000394630.3
CCL7
C-C motif chemokine ligand 7
chr2_+_151357583 0.88 ENST00000243347.5
TNFAIP6
TNF alpha induced protein 6
chr2_+_201129318 0.76 ENST00000417748.1
CFLAR
CASP8 and FADD like apoptosis regulator
chrX_+_150983350 0.68 ENST00000455596.5
ENST00000448905.6
HMGB3
high mobility group box 3
chr15_-_56918571 0.67 ENST00000559000.6
ENSG00000285253.1
novel protein
chr1_-_112618204 0.50 ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chrX_+_9912434 0.49 ENST00000418909.6
SHROOM2
shroom family member 2
chr13_+_97222296 0.48 ENST00000343600.8
ENST00000376673.7
ENST00000679496.1
ENST00000345429.10
MBNL2
muscleblind like splicing regulator 2
chr12_+_25973748 0.44 ENST00000542865.5
RASSF8
Ras association domain family member 8
chr12_-_104050112 0.39 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
GLT8D2
glycosyltransferase 8 domain containing 2
chr16_-_49664225 0.39 ENST00000535559.5
ZNF423
zinc finger protein 423
chr17_+_34255274 0.38 ENST00000580907.5
ENST00000225831.4
CCL2
C-C motif chemokine ligand 2
chr2_-_88992903 0.38 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr19_+_39412650 0.37 ENST00000425673.6
PLEKHG2
pleckstrin homology and RhoGEF domain containing G2
chr7_-_36985060 0.36 ENST00000396040.6
ELMO1
engulfment and cell motility 1
chr22_-_19881163 0.35 ENST00000485358.5
TXNRD2
thioredoxin reductase 2
chr19_+_40613416 0.35 ENST00000599724.5
ENST00000597071.5
LTBP4
latent transforming growth factor beta binding protein 4
chrX_-_112679919 0.34 ENST00000371968.8
LHFPL1
LHFPL tetraspan subfamily member 1
chr17_-_69141878 0.33 ENST00000590645.1
ENST00000284425.7
ABCA6
ATP binding cassette subfamily A member 6
chr16_+_24256313 0.33 ENST00000005284.4
CACNG3
calcium voltage-gated channel auxiliary subunit gamma 3
chr22_-_19881369 0.33 ENST00000462330.5
TXNRD2
thioredoxin reductase 2
chr9_-_13165442 0.32 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr14_-_23057530 0.29 ENST00000397359.7
ENST00000610348.1
CDH24
cadherin 24
chrX_+_65588368 0.29 ENST00000609672.5
MSN
moesin
chr3_+_30606574 0.28 ENST00000295754.10
ENST00000359013.4
TGFBR2
transforming growth factor beta receptor 2
chr2_-_88966767 0.28 ENST00000464162.1
IGKV1-6
immunoglobulin kappa variable 1-6
chr14_-_23057506 0.28 ENST00000487137.7
CDH24
cadherin 24
chr5_-_151924846 0.27 ENST00000274576.9
GLRA1
glycine receptor alpha 1
chr7_+_101127095 0.27 ENST00000223095.5
SERPINE1
serpin family E member 1
chr2_+_188974364 0.27 ENST00000304636.9
ENST00000317840.9
COL3A1
collagen type III alpha 1 chain
chr18_+_3448456 0.27 ENST00000549780.5
TGIF1
TGFB induced factor homeobox 1
chr19_+_11538844 0.26 ENST00000252456.7
CNN1
calponin 1
chr8_-_17697654 0.26 ENST00000297488.10
MTUS1
microtubule associated scaffold protein 1
chr17_+_34285734 0.26 ENST00000305869.4
CCL11
C-C motif chemokine ligand 11
chr5_-_151924824 0.26 ENST00000455880.2
GLRA1
glycine receptor alpha 1
chrX_+_150983299 0.25 ENST00000325307.12
HMGB3
high mobility group box 3
chr9_+_113501359 0.25 ENST00000343817.9
ENST00000394646.7
RGS3
regulator of G protein signaling 3
chr15_+_31326807 0.25 ENST00000307145.4
KLF13
Kruppel like factor 13
chr3_-_37174578 0.25 ENST00000336686.9
LRRFIP2
LRR binding FLII interacting protein 2
chr17_-_33293247 0.24 ENST00000225823.7
ASIC2
acid sensing ion channel subunit 2
chr2_+_33134620 0.24 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
LTBP1
latent transforming growth factor beta binding protein 1
chr16_-_29862890 0.23 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chrX_+_103776493 0.22 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
PLP1
proteolipid protein 1
chrX_+_103776831 0.22 ENST00000621218.5
ENST00000619236.1
PLP1
proteolipid protein 1
chr6_-_30556477 0.22 ENST00000376621.8
GNL1
G protein nucleolar 1 (putative)
chr5_+_132873660 0.22 ENST00000296877.3
LEAP2
liver enriched antimicrobial peptide 2
chr3_-_44510602 0.22 ENST00000436261.6
ZNF852
zinc finger protein 852
chr2_+_33134579 0.21 ENST00000418533.6
LTBP1
latent transforming growth factor beta binding protein 1
chr12_-_53727476 0.21 ENST00000549784.5
ENST00000262059.8
CALCOCO1
calcium binding and coiled-coil domain 1
chr2_-_229232039 0.19 ENST00000354069.6
PID1
phosphotyrosine interaction domain containing 1
chr10_-_93482194 0.19 ENST00000358334.9
ENST00000371488.3
MYOF
myoferlin
chr2_-_89117844 0.19 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr1_-_16980607 0.19 ENST00000375535.4
MFAP2
microfibril associated protein 2
chr12_-_47725483 0.18 ENST00000422538.8
ENDOU
endonuclease, poly(U) specific
chr5_-_149944744 0.18 ENST00000255266.10
ENST00000617647.4
ENST00000613228.1
PDE6A
phosphodiesterase 6A
chr22_+_20917398 0.18 ENST00000354336.8
CRKL
CRK like proto-oncogene, adaptor protein
chr12_-_47725558 0.18 ENST00000229003.7
ENDOU
endonuclease, poly(U) specific
chr11_+_65638085 0.18 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chr14_-_91244669 0.17 ENST00000650645.1
GPR68
G protein-coupled receptor 68
chr19_+_11538767 0.17 ENST00000592923.5
ENST00000535659.6
CNN1
calponin 1
chr15_-_55319107 0.16 ENST00000565225.1
ENST00000436697.3
ENST00000567948.1
ENST00000563262.5
PIGBOS1
RAB27A
PIGB opposite strand 1
RAB27A, member RAS oncogene family
chr17_-_15265230 0.16 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
PMP22
peripheral myelin protein 22
chr11_-_119381629 0.16 ENST00000260187.7
ENST00000455332.6
USP2
ubiquitin specific peptidase 2
chr15_-_31160954 0.16 ENST00000558445.5
ENST00000559177.5
TRPM1
transient receptor potential cation channel subfamily M member 1
chr10_+_103493931 0.16 ENST00000369780.8
NEURL1
neuralized E3 ubiquitin protein ligase 1
chr9_+_94726657 0.16 ENST00000375315.8
ENST00000277198.6
ENST00000297979.9
AOPEP
aminopeptidase O (putative)
chr11_-_62556230 0.15 ENST00000530285.5
AHNAK
AHNAK nucleoprotein
chr4_-_104494882 0.15 ENST00000394767.3
CXXC4
CXXC finger protein 4
chrX_+_150361559 0.15 ENST00000262858.8
MAMLD1
mastermind like domain containing 1
chr1_+_53062052 0.15 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
PODN
podocan
chr19_+_50432885 0.15 ENST00000357701.6
MYBPC2
myosin binding protein C2
chr6_+_112236806 0.15 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4-AS1
ENSG00000281613.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chr11_+_5389377 0.15 ENST00000328611.5
OR51M1
olfactory receptor family 51 subfamily M member 1
chr14_-_38256074 0.15 ENST00000342213.3
CLEC14A
C-type lectin domain containing 14A
chr12_+_52079700 0.14 ENST00000546390.2
SMIM41
small integral membrane protein 41
chr11_-_40294089 0.14 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_-_10231293 0.14 ENST00000646641.1
S1PR2
sphingosine-1-phosphate receptor 2
chr10_+_70052582 0.14 ENST00000676699.1
MACROH2A2
macroH2A.2 histone
chr6_-_165663170 0.14 ENST00000539869.4
PDE10A
phosphodiesterase 10A
chr1_-_153545793 0.13 ENST00000354332.8
ENST00000368716.9
S100A4
S100 calcium binding protein A4
chr12_+_43836043 0.13 ENST00000266534.8
ENST00000551577.5
TMEM117
transmembrane protein 117
chr3_+_49007062 0.13 ENST00000395474.7
ENST00000610967.4
ENST00000429900.6
WDR6
WD repeat domain 6
chr16_+_6019585 0.13 ENST00000547372.5
RBFOX1
RNA binding fox-1 homolog 1
chr4_+_15374541 0.13 ENST00000382383.7
ENST00000429690.5
C1QTNF7
C1q and TNF related 7
chrX_-_102516714 0.13 ENST00000289373.5
TMSB15A
thymosin beta 15A
chr19_+_9140377 0.13 ENST00000360385.7
ENST00000247956.11
ZNF317
zinc finger protein 317
chr7_-_120857124 0.12 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
TSPAN12
tetraspanin 12
chr20_+_59300703 0.12 ENST00000395654.3
EDN3
endothelin 3
chr19_-_42302292 0.12 ENST00000594989.5
PAFAH1B3
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr20_+_59300589 0.12 ENST00000337938.7
ENST00000371025.7
EDN3
endothelin 3
chr3_+_121593363 0.11 ENST00000338040.6
FBXO40
F-box protein 40
chr1_+_42153399 0.11 ENST00000372581.2
GUCA2B
guanylate cyclase activator 2B
chr9_+_97412062 0.11 ENST00000355295.5
TDRD7
tudor domain containing 7
chr14_+_64504743 0.11 ENST00000683701.1
ZBTB1
zinc finger and BTB domain containing 1
chr12_+_112125531 0.11 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr15_+_51377247 0.11 ENST00000396399.6
GLDN
gliomedin
chr17_+_49575828 0.10 ENST00000328741.6
NXPH3
neurexophilin 3
chrX_-_111270474 0.10 ENST00000324068.2
CAPN6
calpain 6
chr11_-_57322197 0.10 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1
chr19_-_15808126 0.10 ENST00000334920.3
OR10H1
olfactory receptor family 10 subfamily H member 1
chr17_-_19748341 0.10 ENST00000395555.7
ALDH3A1
aldehyde dehydrogenase 3 family member A1
chr17_-_19748285 0.09 ENST00000570414.1
ENST00000225740.11
ALDH3A1
aldehyde dehydrogenase 3 family member A1
chr3_+_124584625 0.09 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
KALRN
kalirin RhoGEF kinase
chr20_+_59300547 0.09 ENST00000644821.1
EDN3
endothelin 3
chr20_+_59300402 0.09 ENST00000311585.11
ENST00000371028.6
EDN3
endothelin 3
chr17_-_19748355 0.09 ENST00000494157.6
ALDH3A1
aldehyde dehydrogenase 3 family member A1
chr18_+_54828406 0.09 ENST00000262094.10
RAB27B
RAB27B, member RAS oncogene family
chr12_-_11022620 0.09 ENST00000390673.2
TAS2R19
taste 2 receptor member 19
chr11_-_69013233 0.09 ENST00000309099.7
ENST00000320913.6
MRGPRF
MAS related GPR family member F
chr11_+_73289403 0.09 ENST00000535931.2
ENST00000544437.6
P2RY6
pyrimidinergic receptor P2Y6
chr19_-_35510384 0.09 ENST00000602679.5
ENST00000492341.6
ENST00000472252.6
ENST00000602781.5
ENST00000402589.6
ENST00000458071.5
ENST00000436012.5
ENST00000443640.5
ENST00000450261.1
ENST00000467637.5
ENST00000480502.5
ENST00000474928.5
ENST00000414866.6
ENST00000392206.6
ENST00000488892.5
DMKN
dermokine
chr19_-_51645545 0.09 ENST00000534261.3
SIGLEC5
sialic acid binding Ig like lectin 5
chr19_+_42302098 0.09 ENST00000598490.1
ENST00000341747.8
PRR19
proline rich 19
chr14_+_67240713 0.09 ENST00000677382.1
MPP5
membrane palmitoylated protein 5
chr17_+_50560703 0.09 ENST00000359106.10
CACNA1G
calcium voltage-gated channel subunit alpha1 G
chr4_+_74445302 0.08 ENST00000502307.1
AREG
amphiregulin
chr3_-_160449530 0.08 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr14_+_64503943 0.08 ENST00000556965.1
ENST00000554015.5
ZBTB1
zinc finger and BTB domain containing 1
chr4_+_155903688 0.08 ENST00000536354.3
TDO2
tryptophan 2,3-dioxygenase
chr15_-_74208969 0.07 ENST00000423167.6
ENST00000432245.6
STRA6
signaling receptor and transporter of retinol STRA6
chr11_+_60056653 0.07 ENST00000278865.8
MS4A3
membrane spanning 4-domains A3
chrX_+_48383516 0.07 ENST00000620320.4
ENST00000595689.3
SSX4
SSX family member 4
chr12_+_53985783 0.07 ENST00000513209.1
ENSG00000273049.1
novel protein, readthrough between HOXC10 and HOXC5
chr20_+_58907981 0.07 ENST00000656419.1
GNAS
GNAS complex locus
chr17_+_38428456 0.07 ENST00000622683.5
ENST00000620417.4
ARHGAP23
Rho GTPase activating protein 23
chr14_+_67241278 0.07 ENST00000676464.1
MPP5
membrane palmitoylated protein 5
chr10_-_69573416 0.06 ENST00000242462.5
NEUROG3
neurogenin 3
chr12_-_55727828 0.06 ENST00000546939.5
CD63
CD63 molecule
chr18_+_24155938 0.06 ENST00000582229.1
CABYR
calcium binding tyrosine phosphorylation regulated
chr17_+_50561010 0.06 ENST00000360761.8
ENST00000354983.8
ENST00000352832.9
CACNA1G
calcium voltage-gated channel subunit alpha1 G
chr11_-_69013356 0.06 ENST00000441623.1
MRGPRF
MAS related GPR family member F
chr5_+_132673983 0.06 ENST00000622422.1
ENST00000231449.7
ENST00000350025.2
IL4
interleukin 4
chr18_+_6834473 0.05 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
ARHGAP28
Rho GTPase activating protein 28
chr17_+_44957907 0.05 ENST00000678938.1
NMT1
N-myristoyltransferase 1
chr17_+_62627628 0.05 ENST00000303375.10
MRC2
mannose receptor C type 2
chrX_+_100644183 0.05 ENST00000640889.1
ENST00000373004.5
SRPX2
sushi repeat containing protein X-linked 2
chr1_+_15684284 0.04 ENST00000375799.8
ENST00000375793.2
PLEKHM2
pleckstrin homology and RUN domain containing M2
chr17_-_63972918 0.04 ENST00000435607.3
SCN4A
sodium voltage-gated channel alpha subunit 4
chr2_-_224569782 0.03 ENST00000409096.5
CUL3
cullin 3
chr12_-_55727796 0.03 ENST00000550776.5
CD63
CD63 molecule
chr2_-_1744442 0.03 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
PXDN
peroxidasin
chr4_+_164877164 0.03 ENST00000507152.6
ENST00000515275.1
APELA
apelin receptor early endogenous ligand
chr9_+_84668485 0.03 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
NTRK2
neurotrophic receptor tyrosine kinase 2
chr11_+_60056587 0.03 ENST00000395032.6
ENST00000358152.6
MS4A3
membrane spanning 4-domains A3
chr4_-_151227881 0.03 ENST00000652233.1
ENST00000514152.5
SH3D19
SH3 domain containing 19
chr4_-_86934700 0.03 ENST00000473559.5
ENSG00000285458.1
novel protein
chr15_+_55319202 0.03 ENST00000164305.10
ENST00000566999.5
ENST00000539642.5
PIGB
phosphatidylinositol glycan anchor biosynthesis class B
chr9_+_273026 0.02 ENST00000682249.1
ENST00000453981.5
ENST00000487230.5
ENST00000469391.5
DOCK8
dedicator of cytokinesis 8
chr2_-_65432591 0.02 ENST00000356388.9
SPRED2
sprouty related EVH1 domain containing 2
chr8_-_48921419 0.02 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr1_-_16018005 0.02 ENST00000406363.2
ENST00000411503.5
ENST00000311890.14
ENST00000487046.1
HSPB7
heat shock protein family B (small) member 7
chr3_+_184176949 0.02 ENST00000432591.5
ENST00000431779.5
ENST00000621863.4
AP2M1
adaptor related protein complex 2 subunit mu 1
chr17_+_44349050 0.02 ENST00000639447.1
GRN
granulin precursor
chr3_+_184176778 0.02 ENST00000439647.5
AP2M1
adaptor related protein complex 2 subunit mu 1
chr7_-_135748712 0.02 ENST00000415751.1
FAM180A
family with sequence similarity 180 member A
chr20_+_58150896 0.02 ENST00000371168.4
C20orf85
chromosome 20 open reading frame 85
chr13_-_60013178 0.02 ENST00000498416.2
ENST00000465066.5
DIAPH3
diaphanous related formin 3
chr21_-_34511317 0.02 ENST00000611936.1
ENST00000337385.7
KCNE1
potassium voltage-gated channel subfamily E regulatory subunit 1
chr11_+_15114912 0.02 ENST00000379556.8
INSC
INSC spindle orientation adaptor protein
chrX_-_155334580 0.01 ENST00000369449.7
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr1_+_23743462 0.01 ENST00000609199.1
ELOA
elongin A
chr11_-_34357994 0.01 ENST00000435224.3
ABTB2
ankyrin repeat and BTB domain containing 2
chr1_-_168729187 0.01 ENST00000367817.4
DPT
dermatopontin
chr16_-_29899245 0.01 ENST00000537485.5
SEZ6L2
seizure related 6 homolog like 2
chr11_-_94493798 0.01 ENST00000538923.1
ENST00000540013.5
ENST00000407439.7
ENST00000323929.8
ENST00000393241.8
MRE11
MRE11 homolog, double strand break repair nuclease
chr3_+_159852933 0.01 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr12_+_1629197 0.01 ENST00000397196.7
WNT5B
Wnt family member 5B
chr10_+_7788162 0.00 ENST00000356708.12
ENST00000335698.4
ATP5F1C
ATP synthase F1 subunit gamma
chr1_-_156677400 0.00 ENST00000368223.4
NES
nestin
chr1_+_8945858 0.00 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
CA6
carbonic anhydrase 6
chr1_+_26410809 0.00 ENST00000254231.4
ENST00000326279.11
LIN28A
lin-28 homolog A
chr4_+_47485268 0.00 ENST00000273859.8
ENST00000504445.1
ATP10D
ATPase phospholipid transporting 10D (putative)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:2000502 regulation of natural killer cell chemotaxis(GO:2000501) negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.3 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.3 GO:0001300 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.8 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.3 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.2 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.9 GO:0030728 ovulation(GO:0030728)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.7 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.0 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.0 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0097229 sperm end piece(GO:0097229)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0043218 compact myelin(GO:0043218)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription