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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZFHX3

Z-value: 0.26

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Transcription factors associated with ZFHX3

Gene Symbol Gene ID Gene Info
ZFHX3
ENSG00000140836.17 ZFHX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZFHX3hg38_v1_chr16_-_73048104_730481360.462.1e-02Click!

Activity profile of ZFHX3 motif

Sorted Z-values of ZFHX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_148444674 0.38 ENST00000344721.8
NR3C2
nuclear receptor subfamily 3 group C member 2
chrX_-_32155462 0.26 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
DMD
dystrophin
chrM_-_14669 0.25 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
chr1_-_247758680 0.18 ENST00000408896.4
OR1C1
olfactory receptor family 1 subfamily C member 1
chr2_+_87748087 0.15 ENST00000359481.9
PLGLB2
plasminogen like B2
chr17_-_41098084 0.14 ENST00000318329.6
ENST00000333822.5
KRTAP4-8
keratin associated protein 4-8
chr2_-_87021844 0.14 ENST00000355705.4
ENST00000409310.6
PLGLB1
plasminogen like B1
chr7_+_100428782 0.14 ENST00000414441.5
MEPCE
methylphosphate capping enzyme
chr17_-_69244846 0.14 ENST00000269081.8
ABCA10
ATP binding cassette subfamily A member 10
chr6_+_157036315 0.13 ENST00000637904.1
ARID1B
AT-rich interaction domain 1B
chr2_-_60553558 0.13 ENST00000642439.1
ENST00000356842.9
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr22_+_31092447 0.13 ENST00000455608.5
SMTN
smoothelin
chr6_-_116060859 0.13 ENST00000606080.2
FRK
fyn related Src family tyrosine kinase
chr22_-_30246739 0.12 ENST00000403987.3
ENST00000249075.4
LIF
LIF interleukin 6 family cytokine
chr4_-_154590735 0.12 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
FGA
fibrinogen alpha chain
chr19_+_926001 0.12 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr12_-_2835018 0.11 ENST00000337508.9
NRIP2
nuclear receptor interacting protein 2
chr14_+_39233884 0.11 ENST00000553728.1
MIA2
MIA SH3 domain ER export factor 2
chr4_+_70592253 0.10 ENST00000322937.10
ENST00000613447.4
AMBN
ameloblastin
chr2_-_2324642 0.09 ENST00000650485.1
ENST00000649207.1
MYT1L
myelin transcription factor 1 like
chr2_-_2324323 0.09 ENST00000648339.1
ENST00000647694.1
MYT1L
myelin transcription factor 1 like
chr12_-_56741535 0.08 ENST00000647707.1
ENSG00000285625.1
novel protein
chr20_-_37178966 0.08 ENST00000422138.1
MROH8
maestro heat like repeat family member 8
chr11_+_74748831 0.08 ENST00000299563.5
RNF169
ring finger protein 169
chr7_-_44541318 0.07 ENST00000381160.8
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr2_+_184598520 0.07 ENST00000302277.7
ZNF804A
zinc finger protein 804A
chrM_+_9207 0.07 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr7_-_44541262 0.07 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr1_+_218285283 0.07 ENST00000366932.4
RRP15
ribosomal RNA processing 15 homolog
chr22_+_38705922 0.07 ENST00000216044.10
GTPBP1
GTP binding protein 1
chr2_-_60553409 0.07 ENST00000358510.6
ENST00000643004.1
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr20_+_43558968 0.06 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
SGK2
serum/glucocorticoid regulated kinase 2
chr4_+_73436198 0.06 ENST00000395792.7
AFP
alpha fetoprotein
chr4_+_73436244 0.06 ENST00000226359.2
AFP
alpha fetoprotein
chr14_+_39233908 0.05 ENST00000280082.4
MIA2
MIA SH3 domain ER export factor 2
chr1_-_66801276 0.05 ENST00000304526.3
INSL5
insulin like 5
chr3_-_157503375 0.05 ENST00000362010.7
VEPH1
ventricular zone expressed PH domain containing 1
chr3_-_157503339 0.05 ENST00000392833.6
VEPH1
ventricular zone expressed PH domain containing 1
chr7_-_7535863 0.05 ENST00000399429.8
COL28A1
collagen type XXVIII alpha 1 chain
chr19_-_35812838 0.05 ENST00000653904.2
PRODH2
proline dehydrogenase 2
chr8_-_18684093 0.05 ENST00000428502.6
PSD3
pleckstrin and Sec7 domain containing 3
chr8_-_18684033 0.05 ENST00000614430.3
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_197067234 0.04 ENST00000367412.2
F13B
coagulation factor XIII B chain
chrX_-_123623155 0.04 ENST00000618150.4
THOC2
THO complex 2
chrM_+_8489 0.04 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase membrane subunit 6
chr3_-_49029378 0.04 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
IMPDH2
inosine monophosphate dehydrogenase 2
chr15_+_58431985 0.04 ENST00000433326.2
ENST00000299022.10
LIPC
lipase C, hepatic type
chr1_-_46551647 0.04 ENST00000481882.7
KNCN
kinocilin
chr11_-_61920267 0.04 ENST00000531922.2
ENST00000301773.9
RAB3IL1
RAB3A interacting protein like 1
chr12_+_130953898 0.04 ENST00000261654.10
ADGRD1
adhesion G protein-coupled receptor D1
chr6_+_28349907 0.04 ENST00000252211.7
ENST00000341464.9
ENST00000377255.3
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr4_-_99435336 0.04 ENST00000437033.7
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_57324907 0.04 ENST00000358252.8
TNKS1BP1
tankyrase 1 binding protein 1
chr7_+_151028422 0.04 ENST00000542328.5
ENST00000461373.5
ENST00000297504.10
ENST00000358849.9
ENST00000498578.5
ENST00000477719.5
ENST00000477092.5
ABCB8
ATP binding cassette subfamily B member 8
chr1_-_159714581 0.04 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
CRP
C-reactive protein
chr17_+_7407838 0.04 ENST00000302926.7
NLGN2
neuroligin 2
chr9_-_97938157 0.04 ENST00000616898.2
HEMGN
hemogen
chr22_-_30574572 0.04 ENST00000402369.5
GAL3ST1
galactose-3-O-sulfotransferase 1
chr1_-_160579439 0.04 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84
CD84 molecule
chrX_-_18672101 0.03 ENST00000379984.4
RS1
retinoschisin 1
chr4_-_53591477 0.03 ENST00000263925.8
LNX1
ligand of numb-protein X 1
chr16_+_56191476 0.03 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr2_-_60553618 0.03 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr3_+_35680994 0.03 ENST00000441454.5
ARPP21
cAMP regulated phosphoprotein 21
chr12_-_55296569 0.03 ENST00000358433.3
OR6C6
olfactory receptor family 6 subfamily C member 6
chr6_+_25754699 0.03 ENST00000439485.6
ENST00000377905.9
SLC17A4
solute carrier family 17 member 4
chr6_+_160702238 0.03 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
PLG
plasminogen
chr19_+_53962925 0.03 ENST00000270458.4
CACNG8
calcium voltage-gated channel auxiliary subunit gamma 8
chrX_-_15601077 0.03 ENST00000680121.1
ACE2
angiotensin I converting enzyme 2
chr1_+_159587817 0.03 ENST00000255040.3
APCS
amyloid P component, serum
chrY_+_18546691 0.03 ENST00000309834.8
ENST00000307393.3
ENST00000382856.2
HSFY1
heat shock transcription factor Y-linked 1
chr6_-_30932147 0.02 ENST00000359086.4
SFTA2
surfactant associated 2
chr19_-_45730861 0.02 ENST00000317683.4
FBXO46
F-box protein 46
chr18_+_34976928 0.02 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
MAPRE2
microtubule associated protein RP/EB family member 2
chr5_-_35195236 0.02 ENST00000509839.5
PRLR
prolactin receptor
chr2_+_132416795 0.02 ENST00000329321.4
GPR39
G protein-coupled receptor 39
chr6_-_116126120 0.02 ENST00000452729.1
ENST00000651968.1
ENST00000243222.8
COL10A1
collagen type X alpha 1 chain
chr12_-_130716264 0.02 ENST00000643940.1
RIMBP2
RIMS binding protein 2
chr7_+_48171451 0.02 ENST00000435803.6
ABCA13
ATP binding cassette subfamily A member 13
chr3_-_165078480 0.02 ENST00000264382.8
SI
sucrase-isomaltase
chr6_+_47781982 0.02 ENST00000489301.6
ENST00000638973.1
ENST00000371211.6
ENST00000393699.2
OPN5
opsin 5
chr3_-_167474026 0.02 ENST00000466903.1
ENST00000264677.8
SERPINI2
serpin family I member 2
chr12_+_53954870 0.01 ENST00000243103.4
HOXC12
homeobox C12
chr2_-_40453438 0.01 ENST00000455476.5
SLC8A1
solute carrier family 8 member A1
chr2_+_233729042 0.01 ENST00000482026.6
UGT1A3
UDP glucuronosyltransferase family 1 member A3
chr7_+_48924559 0.01 ENST00000650262.1
CDC14C
cell division cycle 14C
chr3_+_35680932 0.01 ENST00000396481.6
ARPP21
cAMP regulated phosphoprotein 21
chr2_+_233718734 0.01 ENST00000373409.8
UGT1A4
UDP glucuronosyltransferase family 1 member A4
chr6_-_29045175 0.01 ENST00000377175.2
OR2W1
olfactory receptor family 2 subfamily W member 1
chr4_-_52020332 0.01 ENST00000682860.1
LRRC66
leucine rich repeat containing 66
chr8_-_69833338 0.01 ENST00000524945.5
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr2_+_233712905 0.01 ENST00000373414.4
UGT1A5
UDP glucuronosyltransferase family 1 member A5
chr12_-_68159732 0.01 ENST00000229135.4
IFNG
interferon gamma
chr11_+_8019193 0.01 ENST00000534099.5
TUB
TUB bipartite transcription factor
chr6_-_32407123 0.01 ENST00000374993.4
ENST00000544175.2
ENST00000454136.7
ENST00000446536.2
BTNL2
butyrophilin like 2
chr12_+_64497968 0.01 ENST00000676593.1
ENST00000677093.1
TBK1
ENSG00000288665.1
TANK binding kinase 1
novel transcript
chrX_+_85003863 0.00 ENST00000373173.7
APOOL
apolipoprotein O like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)