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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZIC1

Z-value: 0.79

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Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ZIC1
ENSG00000152977.10 ZIC1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg38_v1_chr3_+_147409357_147409381-0.271.9e-01Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr21_+_44600597 6.09 ENST00000609664.2
KRTAP10-7
keratin associated protein 10-7
chr21_+_44697427 5.12 ENST00000618832.1
KRTAP10-12
keratin associated protein 10-12
chr17_+_41226648 2.61 ENST00000377721.3
KRTAP9-2
keratin associated protein 9-2
chr21_-_44592505 2.48 ENST00000400368.1
KRTAP10-6
keratin associated protein 10-6
chr1_+_61404076 2.44 ENST00000357977.5
NFIA
nuclear factor I A
chr4_-_185812209 2.28 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
SORBS2
sorbin and SH3 domain containing 2
chr14_+_38207893 1.87 ENST00000267377.3
SSTR1
somatostatin receptor 1
chr4_+_6269831 1.71 ENST00000503569.5
ENST00000673991.1
ENST00000682275.1
ENST00000226760.5
WFS1
wolframin ER transmembrane glycoprotein
chr17_-_41027198 1.50 ENST00000361883.6
KRTAP1-5
keratin associated protein 1-5
chr4_+_6269869 1.49 ENST00000506362.2
WFS1
wolframin ER transmembrane glycoprotein
chr11_-_134253248 1.36 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
THYN1
thymocyte nuclear protein 1
chr10_-_33334898 1.34 ENST00000395995.5
NRP1
neuropilin 1
chr6_+_132570322 1.34 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr11_+_7576975 1.31 ENST00000684215.1
ENST00000650027.1
PPFIBP2
PPFIA binding protein 2
chr10_-_33334625 1.25 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
NRP1
neuropilin 1
chr11_+_67056875 1.12 ENST00000532559.1
RHOD
ras homolog family member D
chr13_-_44474296 1.07 ENST00000611198.4
TSC22D1
TSC22 domain family member 1
chr14_+_57268963 1.07 ENST00000261558.8
AP5M1
adaptor related protein complex 5 subunit mu 1
chr17_-_55732074 1.04 ENST00000575734.5
TMEM100
transmembrane protein 100
chr22_+_29306582 1.03 ENST00000616432.4
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest specific 2 like 1
chr6_-_145964084 1.00 ENST00000438092.6
ENST00000629427.2
SHPRH
SNF2 histone linker PHD RING helicase
chr13_-_28495079 0.98 ENST00000615840.4
ENST00000282397.9
ENST00000541932.5
ENST00000539099.1
ENST00000639477.1
FLT1
fms related receptor tyrosine kinase 1
chr7_+_150567347 0.97 ENST00000461940.5
GIMAP4
GTPase, IMAP family member 4
chr17_-_19042485 0.91 ENST00000395635.5
GRAP
GRB2 related adaptor protein
chr7_+_150567382 0.90 ENST00000255945.4
ENST00000479232.1
GIMAP4
GTPase, IMAP family member 4
chrX_+_24693879 0.90 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
POLA1
DNA polymerase alpha 1, catalytic subunit
chr9_-_124500986 0.89 ENST00000373587.3
NR5A1
nuclear receptor subfamily 5 group A member 1
chr1_-_94121105 0.86 ENST00000649773.1
ENST00000370225.4
ABCA4
ATP binding cassette subfamily A member 4
chr19_-_42255119 0.83 ENST00000222329.9
ENST00000594664.1
ERF
ENSG00000268643.2
ETS2 repressor factor
novel protein
chr19_+_33796846 0.83 ENST00000590771.5
ENST00000589786.5
ENST00000284006.10
ENST00000683859.1
ENST00000588881.5
KCTD15
potassium channel tetramerization domain containing 15
chr17_+_62627628 0.81 ENST00000303375.10
MRC2
mannose receptor C type 2
chr3_+_50155024 0.77 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
SEMA3F
semaphorin 3F
chr16_+_3135121 0.77 ENST00000576416.5
ENST00000416391.6
ZNF213
zinc finger protein 213
chr8_-_119673368 0.72 ENST00000427067.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_-_33335074 0.68 ENST00000432372.6
NRP1
neuropilin 1
chr3_+_149129610 0.68 ENST00000460120.5
ENST00000296051.7
HPS3
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1
chr11_+_67056805 0.67 ENST00000308831.7
RHOD
ras homolog family member D
chr2_-_98936155 0.65 ENST00000428096.5
ENST00000397899.7
ENST00000420294.1
CRACDL
CRACD like
chr21_+_44697172 0.64 ENST00000400365.3
KRTAP10-12
keratin associated protein 10-12
chr17_-_69060906 0.64 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ABCA9
ATP binding cassette subfamily A member 9
chr12_+_13044371 0.63 ENST00000197268.13
FAM234B
family with sequence similarity 234 member B
chr9_-_16870662 0.60 ENST00000380672.9
BNC2
basonuclin 2
chr2_+_230878139 0.59 ENST00000620962.1
ITM2C
integral membrane protein 2C
chr14_+_64504574 0.59 ENST00000358738.3
ZBTB1
zinc finger and BTB domain containing 1
chr12_-_58920465 0.58 ENST00000320743.8
LRIG3
leucine rich repeats and immunoglobulin like domains 3
chr14_-_68979436 0.54 ENST00000193403.10
ACTN1
actinin alpha 1
chr21_-_38498415 0.53 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chrX_-_154805386 0.52 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
MPP1
membrane palmitoylated protein 1
chr1_+_99850485 0.51 ENST00000370165.7
ENST00000370163.7
ENST00000294724.8
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr8_-_81842192 0.51 ENST00000353788.8
ENST00000520618.5
ENST00000518183.5
ENST00000396330.6
ENST00000519119.5
SNX16
sorting nexin 16
chrX_-_154751017 0.51 ENST00000369575.7
ENST00000369568.8
ENST00000424127.3
GAB3
GRB2 associated binding protein 3
chr8_-_81841958 0.51 ENST00000519817.5
ENST00000521773.5
ENST00000523757.5
ENST00000345957.9
SNX16
sorting nexin 16
chr14_+_32934383 0.50 ENST00000551634.6
NPAS3
neuronal PAS domain protein 3
chr1_-_59926724 0.50 ENST00000371204.4
CYP2J2
cytochrome P450 family 2 subfamily J member 2
chr16_+_28846674 0.50 ENST00000322610.12
SH2B1
SH2B adaptor protein 1
chr1_+_99850348 0.50 ENST00000361915.8
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr15_+_80059568 0.49 ENST00000613266.4
ENST00000561060.5
ZFAND6
zinc finger AN1-type containing 6
chr7_-_103149182 0.49 ENST00000417955.5
ENST00000341533.8
ENST00000425379.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chrX_-_154805516 0.49 ENST00000413259.7
MPP1
membrane palmitoylated protein 1
chrX_-_130165825 0.47 ENST00000675240.1
ENST00000319908.8
ENST00000674546.1
ENST00000287295.8
AIFM1
apoptosis inducing factor mitochondria associated 1
chr15_+_80059635 0.46 ENST00000559157.5
ZFAND6
zinc finger AN1-type containing 6
chr1_+_16043736 0.45 ENST00000619181.4
CLCNKB
chloride voltage-gated channel Kb
chr7_-_35695120 0.45 ENST00000311350.8
ENST00000396081.5
HERPUD2
HERPUD family member 2
chr19_-_58098203 0.43 ENST00000600845.1
ENST00000240727.10
ENST00000600897.5
ENST00000421612.6
ENST00000601063.1
ENST00000601144.6
ZSCAN18
zinc finger and SCAN domain containing 18
chr15_+_80060113 0.42 ENST00000618205.4
ZFAND6
zinc finger AN1-type containing 6
chrX_-_130165873 0.42 ENST00000676229.1
AIFM1
apoptosis inducing factor mitochondria associated 1
chr19_+_44809089 0.42 ENST00000270233.12
ENST00000591520.6
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr19_-_45639104 0.41 ENST00000586770.5
ENST00000591721.5
ENST00000245925.8
ENST00000590043.5
ENST00000589876.5
EML2
EMAP like 2
chr11_-_73598067 0.41 ENST00000450446.6
ENST00000356467.5
FAM168A
family with sequence similarity 168 member A
chr11_-_73598183 0.40 ENST00000064778.8
FAM168A
family with sequence similarity 168 member A
chr19_+_44809053 0.40 ENST00000611077.5
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr5_+_141135199 0.40 ENST00000231134.8
ENST00000623915.1
PCDHB5
protocadherin beta 5
chr3_-_195442977 0.40 ENST00000326793.11
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr21_+_30396030 0.38 ENST00000355459.4
KRTAP13-1
keratin associated protein 13-1
chr17_+_18377769 0.38 ENST00000399134.5
EVPLL
envoplakin like
chrX_-_130165699 0.38 ENST00000676328.1
ENST00000675857.1
ENST00000675427.1
ENST00000675092.1
AIFM1
apoptosis inducing factor mitochondria associated 1
chr19_+_44905785 0.38 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
APOE
apolipoprotein E
chrX_-_130165664 0.37 ENST00000535724.6
ENST00000346424.6
ENST00000676436.1
AIFM1
apoptosis inducing factor mitochondria associated 1
chr17_-_41034871 0.37 ENST00000344363.7
KRTAP1-3
keratin associated protein 1-3
chr5_-_141673160 0.37 ENST00000513878.5
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chrX_-_79367307 0.36 ENST00000373298.7
ITM2A
integral membrane protein 2A
chr1_-_153616289 0.36 ENST00000368701.5
ENST00000344616.4
S100A14
S100 calcium binding protein A14
chr1_+_161118083 0.35 ENST00000368009.7
ENST00000368007.8
ENST00000392190.9
ENST00000368008.5
NIT1
nitrilase 1
chr12_-_10884244 0.35 ENST00000543626.4
PRH1
proline rich protein HaeIII subfamily 1
chr19_+_13024917 0.35 ENST00000587260.1
NFIX
nuclear factor I X
chr7_-_103149056 0.35 ENST00000465647.6
ENST00000418294.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr8_+_25184668 0.34 ENST00000276440.12
ENST00000410074.5
DOCK5
dedicator of cytokinesis 5
chrX_+_46912276 0.33 ENST00000424392.5
ENST00000611250.4
JADE3
jade family PHD finger 3
chrX_+_46912412 0.33 ENST00000614628.5
JADE3
jade family PHD finger 3
chr19_+_35449584 0.33 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr3_-_86991135 0.32 ENST00000398399.7
VGLL3
vestigial like family member 3
chr16_+_788614 0.31 ENST00000262315.14
ENST00000455171.6
ENST00000317063.10
CHTF18
chromosome transmission fidelity factor 18
chr16_+_721596 0.31 ENST00000568916.1
ANTKMT
adenine nucleotide translocase lysine methyltransferase
chr12_-_25648544 0.29 ENST00000540106.5
ENST00000445693.5
ENST00000545543.1
LMNTD1
lamin tail domain containing 1
chr16_-_2329687 0.29 ENST00000567910.1
ABCA3
ATP binding cassette subfamily A member 3
chr13_-_99971739 0.28 ENST00000267294.4
ZIC5
Zic family member 5
chr9_-_16870702 0.27 ENST00000380667.6
ENST00000545497.5
ENST00000486514.5
BNC2
basonuclin 2
chr12_+_26938454 0.27 ENST00000229395.8
ENST00000544111.5
ENST00000546072.5
ENST00000327214.5
FGFR1OP2
FGFR1 oncogene partner 2
chr16_+_30985181 0.27 ENST00000262520.10
ENST00000297679.10
ENST00000562932.5
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_-_2171805 0.27 ENST00000381178.5
ENST00000381175.5
ENST00000333684.9
ENST00000352909.8
TH
tyrosine hydroxylase
chr19_+_36604817 0.27 ENST00000423582.5
ZNF382
zinc finger protein 382
chr11_-_40294089 0.27 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr4_+_88523810 0.27 ENST00000512194.2
ENST00000598772.1
ENST00000597259.2
ENSG00000287542.1
PIGY-DT
HECT and RLD domain containing E3 ubiquitin protein ligase 3
PIGY divergent transcript
chr4_-_55636259 0.26 ENST00000505262.5
ENST00000507338.1
NMU
neuromedin U
chr1_+_22636577 0.26 ENST00000374642.8
ENST00000438241.1
C1QA
complement C1q A chain
chr4_-_88523740 0.25 ENST00000273968.5
ENST00000527353.2
PYURF
PIGY
PIGY upstream reading frame
phosphatidylinositol glycan anchor biosynthesis class Y
chr5_+_157743703 0.24 ENST00000286307.6
LSM11
LSM11, U7 small nuclear RNA associated
chr16_+_55479188 0.24 ENST00000219070.9
MMP2
matrix metallopeptidase 2
chr19_-_49665603 0.23 ENST00000596756.5
IRF3
interferon regulatory factor 3
chr6_-_34248989 0.23 ENST00000481533.5
ENST00000468145.1
ENST00000476320.6
ENST00000394990.8
SMIM29
small integral membrane protein 29
chr2_+_11539833 0.23 ENST00000263834.9
GREB1
growth regulating estrogen receptor binding 1
chr2_+_119431846 0.22 ENST00000306406.5
TMEM37
transmembrane protein 37
chr17_-_17206264 0.22 ENST00000321560.4
PLD6
phospholipase D family member 6
chr1_-_211133945 0.22 ENST00000640044.1
ENST00000640566.1
KCNH1
potassium voltage-gated channel subfamily H member 1
chr19_-_6433754 0.21 ENST00000321510.7
SLC25A41
solute carrier family 25 member 41
chr15_+_41621134 0.21 ENST00000566718.6
MGA
MAX dimerization protein MGA
chr15_+_77420880 0.21 ENST00000336216.9
ENST00000558176.1
HMG20A
high mobility group 20A
chr14_+_35826298 0.21 ENST00000216807.12
BRMS1L
BRMS1 like transcriptional repressor
chr6_-_34249102 0.20 ENST00000636500.1
SMIM29
small integral membrane protein 29
chr12_-_102478539 0.19 ENST00000424202.6
IGF1
insulin like growth factor 1
chr15_+_77420668 0.19 ENST00000381714.7
ENST00000558651.5
HMG20A
high mobility group 20A
chr4_-_65669935 0.19 ENST00000354839.8
ENST00000432638.6
EPHA5
EPH receptor A5
chr1_+_15438435 0.18 ENST00000375943.6
ENST00000375949.5
CTRC
chymotrypsin C
chr17_-_41047267 0.18 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr10_+_96043394 0.17 ENST00000403870.7
ENST00000265992.9
ENST00000465148.3
CCNJ
cyclin J
chr4_-_40515967 0.17 ENST00000381795.10
RBM47
RNA binding motif protein 47
chr19_-_3063101 0.17 ENST00000221561.12
TLE5
TLE family member 5, transcriptional modulator
chrX_+_91779367 0.17 ENST00000682573.1
PCDH11X
protocadherin 11 X-linked
chr14_+_22271921 0.17 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr1_+_16043776 0.16 ENST00000375679.9
CLCNKB
chloride voltage-gated channel Kb
chr6_-_168319762 0.15 ENST00000366795.4
DACT2
dishevelled binding antagonist of beta catenin 2
chr4_+_678189 0.15 ENST00000507804.1
MYL5
myosin light chain 5
chr8_+_84184875 0.15 ENST00000517638.5
ENST00000522647.1
RALYL
RALY RNA binding protein like
chr2_+_169069537 0.15 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
DHRS9
dehydrogenase/reductase 9
chr1_+_61952036 0.15 ENST00000646453.1
ENST00000635137.1
PATJ
PATJ crumbs cell polarity complex component
chr14_-_68979314 0.15 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
ACTN1
actinin alpha 1
chr6_+_31572279 0.15 ENST00000418386.3
LTA
lymphotoxin alpha
chr6_+_31762996 0.14 ENST00000415669.3
ENST00000425424.4
SAPCD1
suppressor APC domain containing 1
chr14_+_64504743 0.14 ENST00000683701.1
ZBTB1
zinc finger and BTB domain containing 1
chr1_-_43368039 0.14 ENST00000413844.3
ELOVL1
ELOVL fatty acid elongase 1
chr12_+_4809176 0.14 ENST00000280684.3
KCNA6
potassium voltage-gated channel subfamily A member 6
chr4_+_118685373 0.13 ENST00000388822.10
ENST00000508801.1
METTL14
methyltransferase like 14
chr6_-_168319691 0.12 ENST00000610183.1
ENST00000607983.1
DACT2
dishevelled binding antagonist of beta catenin 2
chr11_-_62921339 0.12 ENST00000306960.4
CHRM1
cholinergic receptor muscarinic 1
chr1_-_211134135 0.12 ENST00000638983.1
ENST00000271751.10
ENST00000639952.1
ENSG00000284299.1
KCNH1
novel protein
potassium voltage-gated channel subfamily H member 1
chr15_-_83067199 0.11 ENST00000261721.9
BTBD1
BTB domain containing 1
chr14_-_64504570 0.11 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr12_-_52520371 0.11 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
KRT5
keratin 5
chr16_-_31088963 0.11 ENST00000280606.6
PRSS53
serine protease 53
chrX_-_47574738 0.11 ENST00000640721.1
SYN1
synapsin I
chr22_+_49960760 0.10 ENST00000360612.5
PIM3
Pim-3 proto-oncogene, serine/threonine kinase
chr2_-_142131004 0.10 ENST00000434794.1
ENST00000389484.8
LRP1B
LDL receptor related protein 1B
chr6_-_168075831 0.10 ENST00000440994.6
FRMD1
FERM domain containing 1
chr19_-_3062464 0.10 ENST00000327141.9
TLE5
TLE family member 5, transcriptional modulator
chr22_-_23580223 0.09 ENST00000249053.3
ENST00000330377.3
ENST00000438703.1
IGLL1
immunoglobulin lambda like polypeptide 1
chr9_-_35103108 0.09 ENST00000356493.10
STOML2
stomatin like 2
chr4_-_65670478 0.09 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPHA5
EPH receptor A5
chr17_+_38428456 0.09 ENST00000622683.5
ENST00000620417.4
ARHGAP23
Rho GTPase activating protein 23
chr5_+_112976757 0.09 ENST00000389063.3
DCP2
decapping mRNA 2
chr4_-_65670339 0.09 ENST00000273854.7
EPHA5
EPH receptor A5
chrX_-_135893410 0.08 ENST00000682849.1
CT45A10
cancer/testis antigen family 45 member A10
chr14_-_68979274 0.07 ENST00000394419.9
ACTN1
actinin alpha 1
chr17_-_17836997 0.07 ENST00000395757.6
SREBF1
sterol regulatory element binding transcription factor 1
chr19_-_14475307 0.07 ENST00000292513.4
PTGER1
prostaglandin E receptor 1
chr1_+_111449442 0.07 ENST00000369722.8
ENST00000483994.1
ATP5PB
ATP synthase peripheral stalk-membrane subunit b
chr2_-_29074515 0.07 ENST00000331664.6
PCARE
photoreceptor cilium actin regulator
chr2_-_74553049 0.06 ENST00000409549.5
LOXL3
lysyl oxidase like 3
chr9_-_35103178 0.06 ENST00000452248.6
ENST00000619795.4
STOML2
stomatin like 2
chr19_-_16660104 0.06 ENST00000593459.5
ENST00000627144.2
ENST00000358726.6
ENST00000487416.7
ENST00000597711.5
ENSG00000268790.5
SMIM7
novel protein
small integral membrane protein 7
chr1_+_16022004 0.05 ENST00000439316.6
CLCNKA
chloride voltage-gated channel Ka
chr13_+_42138042 0.05 ENST00000628433.2
ENST00000536612.3
DGKH
diacylglycerol kinase eta
chr7_-_124929801 0.05 ENST00000653241.1
ENST00000664366.1
ENST00000446993.6
ENST00000654766.1
ENST00000357628.8
ENST00000609702.5
POT1
protection of telomeres 1
chr14_+_22871732 0.04 ENST00000359591.9
LRP10
LDL receptor related protein 10
chr11_-_110712392 0.04 ENST00000683387.1
ARHGAP20
Rho GTPase activating protein 20
chr19_-_3062772 0.04 ENST00000586742.5
TLE5
TLE family member 5, transcriptional modulator
chr1_-_43367956 0.04 ENST00000372458.8
ELOVL1
ELOVL fatty acid elongase 1
chr6_+_31571957 0.03 ENST00000454783.5
LTA
lymphotoxin alpha
chr1_-_211134061 0.03 ENST00000639602.1
ENST00000638498.1
ENST00000367007.5
ENSG00000284299.1
KCNH1
novel protein
potassium voltage-gated channel subfamily H member 1
chr7_-_124929938 0.03 ENST00000668382.1
ENST00000655761.1
ENST00000393329.5
POT1
protection of telomeres 1
chr3_+_52420955 0.03 ENST00000465863.1
PHF7
PHD finger protein 7
chr12_+_5432101 0.02 ENST00000423158.4
NTF3
neurotrophin 3
chr1_-_43367689 0.02 ENST00000621943.4
ELOVL1
ELOVL fatty acid elongase 1
chr11_+_15073562 0.02 ENST00000533448.1
ENST00000324229.11
CALCB
calcitonin related polypeptide beta
chr2_+_79120474 0.02 ENST00000233735.2
REG1A
regenerating family member 1 alpha
chr18_+_63752935 0.02 ENST00000425392.5
ENST00000336429.6
SERPINB7
serpin family B member 7
chr17_-_41041447 0.02 ENST00000306271.5
KRTAP1-1
keratin associated protein 1-1
chr20_-_32743406 0.01 ENST00000474815.2
ENST00000446419.6
ENST00000278980.11
ENST00000642484.1
ENST00000646357.1
COMMD7
ENSG00000285382.1
COMM domain containing 7
novel protein
chr2_+_233760265 0.01 ENST00000305208.10
ENST00000360418.4
UGT1A1
UDP glucuronosyltransferase family 1 member A1
chr17_-_58544315 0.01 ENST00000671766.1
ENST00000672673.2
ENST00000321691.3
SEPTIN4
septin 4
chr3_+_141386862 0.01 ENST00000513258.5
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_51977833 0.01 ENST00000637978.1
ABHD14A-ACY1
ABHD14A-ACY1 readthrough
chr7_+_38977904 0.00 ENST00000518318.7
ENST00000403058.6
POU6F2
POU class 6 homeobox 2
chr6_+_41787651 0.00 ENST00000398884.7
ENST00000398881.4
TOMM6
translocase of outer mitochondrial membrane 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.8 3.3 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4 1.6 GO:1904045 cellular response to aldosterone(GO:1904045)
0.4 1.9 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.3 0.8 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 0.8 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.7 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.2 0.9 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.9 GO:0007538 primary sex determination(GO:0007538)
0.2 1.1 GO:0035900 response to isolation stress(GO:0035900)
0.1 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.4 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.4 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.1 18.0 GO:0031424 keratinization(GO:0031424)
0.1 0.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 1.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 2.4 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 0.3 GO:1900108 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 2.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 1.0 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 1.4 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 1.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.7 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.0 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.9 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.5 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 GO:0097443 sorting endosome(GO:0097443)
0.2 0.7 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 17.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.3 GO:0005602 complement component C1 complex(GO:0005602)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 3.2 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.4 1.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 0.9 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.3 0.8 GO:0005055 laminin receptor activity(GO:0005055)
0.2 1.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 0.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 2.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0034617 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) tetrahydrobiopterin binding(GO:0034617)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.0 3.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.7 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.9 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 3.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway