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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZIC3_ZIC4

Z-value: 0.87

Motif logo

Transcription factors associated with ZIC3_ZIC4

Gene Symbol Gene ID Gene Info
ENSG00000156925.12 ZIC3
ENSG00000174963.18 ZIC4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC3hg38_v1_chrX_+_137566119_137566167-0.386.2e-02Click!
ZIC4hg38_v1_chr3_-_147406520_147406549-0.116.0e-01Click!

Activity profile of ZIC3_ZIC4 motif

Sorted Z-values of ZIC3_ZIC4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_1763832 7.43 ENST00000520991.3
CLN8 transmembrane ER and ERGIC protein
chr8_+_1763752 7.31 ENST00000519254.2
CLN8 transmembrane ER and ERGIC protein
chr19_-_12881460 1.36 ENST00000592506.1
deoxyribonuclease 2, lysosomal
chr3_-_64268161 1.29 ENST00000564377.6
prickle planar cell polarity protein 2
chr16_-_30021288 0.96 ENST00000574405.5
double C2 domain alpha
chr16_-_49856105 0.79 ENST00000563137.7
zinc finger protein 423
chr19_+_13024917 0.75 ENST00000587260.1
nuclear factor I X
chrX_+_24693879 0.74 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
DNA polymerase alpha 1, catalytic subunit
chr6_+_143536811 0.70 ENST00000367584.8
phosphatase and actin regulator 2
chr2_+_20447065 0.68 ENST00000272233.6
ras homolog family member B
chr7_+_150991005 0.68 ENST00000297494.8
nitric oxide synthase 3
chr3_-_149086488 0.65 ENST00000392912.6
ENST00000465259.5
ENST00000310053.10
ENST00000494055.5
helicase like transcription factor
chr19_+_44748673 0.61 ENST00000164227.10
BCL3 transcription coactivator
chr12_-_51026141 0.58 ENST00000541174.6
solute carrier family 11 member 2
chr17_-_41027198 0.54 ENST00000361883.6
keratin associated protein 1-5
chr20_+_36573458 0.54 ENST00000373874.6
TGFB induced factor homeobox 2
chr10_+_79706328 0.52 ENST00000342531.2
NUT family member 2B
chr2_-_110115811 0.50 ENST00000272462.3
mal, T cell differentiation protein like
chr3_-_17742498 0.49 ENST00000429383.8
ENST00000446863.5
ENST00000414349.5
ENST00000428355.5
ENST00000425944.5
ENST00000445294.5
ENST00000444471.5
ENST00000415814.6
TBC1 domain family member 5
chr19_-_12881429 0.47 ENST00000222219.8
deoxyribonuclease 2, lysosomal
chr3_+_149129610 0.45 ENST00000460120.5
ENST00000296051.7
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1
chr19_+_1908258 0.45 ENST00000411971.5
ENST00000588907.2
secretory carrier membrane protein 4
chr12_+_93572664 0.44 ENST00000551556.2
suppressor of cytokine signaling 2
chr1_+_32292067 0.44 ENST00000373548.8
ENST00000428704.1
histone deacetylase 1
chr12_-_58920465 0.43 ENST00000320743.8
leucine rich repeats and immunoglobulin like domains 3
chr17_+_40062810 0.43 ENST00000584985.5
ENST00000264637.8
thyroid hormone receptor alpha
chr6_+_15248855 0.43 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr10_+_110497898 0.42 ENST00000369583.4
dual specificity phosphatase 5
chr4_+_77158418 0.42 ENST00000509972.1
cyclin G2
chr9_+_137077467 0.42 ENST00000409858.8
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
chr7_-_50450324 0.42 ENST00000356889.8
ENST00000420829.5
ENST00000448788.1
ENST00000395556.6
ENST00000433017.6
ENST00000422854.5
ENST00000435566.5
ENST00000617389.4
ENST00000611938.4
ENST00000615084.4
fidgetin like 1
chrX_+_10015226 0.42 ENST00000380861.9
WWC family member 3
chr9_-_137188540 0.40 ENST00000323927.3
anaphase promoting complex subunit 2
chrX_+_41333342 0.40 ENST00000629496.3
ENST00000625837.2
ENST00000626301.2
DEAD-box helicase 3 X-linked
chr22_+_19479826 0.39 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chr20_+_36573589 0.39 ENST00000373872.9
ENST00000650844.1
TGFB induced factor homeobox 2
chr5_-_177496845 0.38 ENST00000506537.1
PDZ and LIM domain 7
chr7_+_155458129 0.38 ENST00000297375.4
engrailed homeobox 2
chr21_+_44600597 0.38 ENST00000609664.2
keratin associated protein 10-7
chr4_-_148442342 0.38 ENST00000358102.8
nuclear receptor subfamily 3 group C member 2
chr22_+_19479457 0.38 ENST00000407835.6
ENST00000455750.6
cell division cycle 45
chr10_+_28677487 0.37 ENST00000375533.6
BMP and activin membrane bound inhibitor
chr6_+_144583198 0.37 ENST00000367526.8
utrophin
chr22_-_21867368 0.37 ENST00000544786.1
mitogen-activated protein kinase 1
chr1_-_150579530 0.36 ENST00000307940.3
ENST00000678610.1
ENST00000678770.1
ENST00000369026.3
MCL1 apoptosis regulator, BCL2 family member
chr14_-_105168753 0.36 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr8_-_80080816 0.36 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr4_-_148442508 0.36 ENST00000625323.2
nuclear receptor subfamily 3 group C member 2
chr2_+_241687059 0.36 ENST00000636051.1
inhibitor of growth family member 5
chr9_-_137302264 0.35 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr17_+_47253817 0.35 ENST00000559488.7
ENST00000571680.1
integrin subunit beta 3
chr7_-_101165114 0.35 ENST00000445482.2
VGF nerve growth factor inducible
chr5_-_177496802 0.35 ENST00000506161.5
PDZ and LIM domain 7
chr16_+_29455105 0.35 ENST00000567248.1
SLX1 homolog B, structure-specific endonuclease subunit
chr7_-_140478975 0.34 ENST00000474576.5
ENST00000473444.1
ENST00000471104.5
makorin ring finger protein 1
chr11_-_86068743 0.34 ENST00000356360.9
phosphatidylinositol binding clathrin assembly protein
chr14_+_95876385 0.34 ENST00000504119.1
TCL1 upstream neural differentiation-associated RNA
chr8_+_89757789 0.34 ENST00000220751.5
receptor interacting serine/threonine kinase 2
chr13_+_34942263 0.34 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr21_-_43427131 0.33 ENST00000270162.8
salt inducible kinase 1
chr17_-_44199206 0.33 ENST00000589805.1
ataxin 7 like 3
chr19_-_14206168 0.33 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr1_-_44843240 0.33 ENST00000372192.4
patched 2
chr21_+_44697427 0.33 ENST00000618832.1
keratin associated protein 10-12
chr16_-_800705 0.33 ENST00000248150.5
G protein subunit gamma 13
chr22_+_19718390 0.32 ENST00000383045.7
ENST00000438754.6
septin 5
chr1_-_154956086 0.32 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBX homeobox interacting protein 1
chr17_-_5500997 0.31 ENST00000568641.2
novel protein
chr16_+_30985181 0.31 ENST00000262520.10
ENST00000297679.10
ENST00000562932.5
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr8_+_43140405 0.30 ENST00000379644.9
heparan-alpha-glucosaminide N-acetyltransferase
chr22_+_29306582 0.30 ENST00000616432.4
ENST00000416823.1
ENST00000428622.1
growth arrest specific 2 like 1
chr14_+_95876430 0.30 ENST00000678517.1
TCL1 upstream neural differentiation-associated RNA
chr7_-_101165558 0.30 ENST00000611537.1
ENST00000249330.3
VGF nerve growth factor inducible
chr22_+_19760714 0.29 ENST00000649276.2
T-box transcription factor 1
chr1_-_21176836 0.29 ENST00000634879.2
ENST00000400422.6
ENST00000602326.5
ENST00000411888.5
ENST00000438975.5
ENST00000374935.7
eukaryotic translation initiation factor 4 gamma 3
chr2_-_27119012 0.29 ENST00000312734.8
cell growth regulator with EF-hand domain 1
chr8_-_79767843 0.29 ENST00000337919.9
hes related family bHLH transcription factor with YRPW motif 1
chr19_+_49114324 0.29 ENST00000391864.7
lin-7 homolog B, crumbs cell polarity complex component
chr16_-_90019414 0.29 ENST00000002501.11
dysbindin domain containing 1
chr14_-_100375333 0.29 ENST00000557297.5
ENST00000555813.5
ENST00000392882.7
ENST00000557135.5
ENST00000556698.5
ENST00000554509.5
ENST00000555410.5
tryptophanyl-tRNA synthetase 1
chr17_+_41237998 0.28 ENST00000254072.7
keratin associated protein 9-8
chr11_+_87037820 0.28 ENST00000340353.11
transmembrane protein 135
chr8_-_79767462 0.28 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
hes related family bHLH transcription factor with YRPW motif 1
chr9_-_34662654 0.28 ENST00000259631.5
C-C motif chemokine ligand 27
chr21_+_44573724 0.28 ENST00000622352.3
ENST00000400374.4
ENST00000616689.2
keratin associated protein 10-4
chrX_+_107628428 0.28 ENST00000643795.2
ENST00000372418.4
ENST00000646815.1
ENST00000372435.10
ENST00000372419.3
ENST00000676092.1
phosphoribosyl pyrophosphate synthetase 1
chr7_-_106284524 0.28 ENST00000681936.1
ENST00000680786.1
ENST00000681550.1
nicotinamide phosphoribosyltransferase
chr15_+_73683938 0.27 ENST00000567189.5
CD276 molecule
chr12_-_124863902 0.27 ENST00000339570.9
ENST00000680556.1
scavenger receptor class B member 1
chr5_-_111756245 0.27 ENST00000447165.6
neuronal regeneration related protein
chr12_-_124863783 0.27 ENST00000546215.5
ENST00000415380.6
ENST00000545493.1
ENST00000261693.11
ENST00000680596.1
scavenger receptor class B member 1
chr7_+_107168961 0.27 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HMG-box transcription factor 1
chr16_-_57284654 0.27 ENST00000613167.4
ENST00000219207.10
ENST00000569059.5
plasmolipin
chr10_+_47322450 0.27 ENST00000581492.3
growth differentiation factor 2
chr7_-_106284934 0.27 ENST00000680468.1
ENST00000489358.5
ENST00000491027.6
ENST00000441045.6
ENST00000417537.2
nicotinamide phosphoribosyltransferase
chr4_-_148444674 0.27 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr15_+_31326807 0.27 ENST00000307145.4
Kruppel like factor 13
chr19_+_50358571 0.27 ENST00000652203.1
nuclear receptor subfamily 1 group H member 2
chr3_-_129316276 0.26 ENST00000333762.6
H1.10 linker histone
chr7_-_712437 0.26 ENST00000360274.8
protein kinase cAMP-dependent type I regulatory subunit beta
chr7_+_75882044 0.26 ENST00000428119.1
rhomboid domain containing 2
chr12_-_51026325 0.26 ENST00000547198.5
ENST00000643884.1
solute carrier family 11 member 2
chr19_-_12722547 0.25 ENST00000592287.5
transportin 2
chr19_-_1174227 0.25 ENST00000587024.5
ENST00000361757.8
strawberry notch homolog 2
chr2_-_27263034 0.24 ENST00000233535.9
solute carrier family 30 member 3
chr21_+_44697172 0.24 ENST00000400365.3
keratin associated protein 10-12
chr21_+_32412648 0.24 ENST00000401402.7
ENST00000382699.7
ENST00000300255.7
eva-1 homolog C
chr3_+_50155024 0.24 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr17_-_41489907 0.23 ENST00000328119.11
keratin 36
chr3_-_112638097 0.23 ENST00000461431.1
coiled-coil domain containing 80
chr10_-_125161019 0.23 ENST00000411419.6
C-terminal binding protein 2
chr5_-_177497561 0.23 ENST00000359895.6
ENST00000355572.6
ENST00000393551.5
ENST00000505074.5
ENST00000393546.8
ENST00000355841.7
PDZ and LIM domain 7
chr6_+_15246054 0.23 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr10_-_13099652 0.23 ENST00000378839.1
coiled-coil domain containing 3
chr5_+_141373878 0.23 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr5_+_77210881 0.23 ENST00000340978.7
ENST00000346042.7
ENST00000342343.8
ENST00000333194.8
phosphodiesterase 8B
chr4_-_105473709 0.23 ENST00000502596.5
inorganic pyrophosphatase 2
chr2_+_79512993 0.23 ENST00000496558.5
ENST00000451966.5
ENST00000402739.9
ENST00000629316.2
catenin alpha 2
chr11_-_65900413 0.23 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr3_+_111732474 0.22 ENST00000393923.7
pleckstrin homology like domain family B member 2
chr19_-_49362376 0.22 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEA domain transcription factor 2
chr11_-_78417788 0.22 ENST00000361507.5
GRB2 associated binding protein 2
chr1_+_155323911 0.22 ENST00000368347.8
RUN and SH3 domain containing 1
chr7_-_712940 0.22 ENST00000544935.5
ENST00000430040.5
ENST00000456696.2
ENST00000406797.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr19_-_58558871 0.22 ENST00000595957.5
ubiquitin conjugating enzyme E2 M
chr5_-_180591488 0.22 ENST00000292641.4
secretoglobin family 3A member 1
chr17_+_80220406 0.22 ENST00000573809.5
ENST00000361193.8
ENST00000574967.5
ENST00000576126.5
ENST00000411502.7
ENST00000546047.6
ENST00000572725.5
solute carrier family 26 member 11
chr1_+_28887166 0.22 ENST00000347529.7
erythrocyte membrane protein band 4.1
chr2_-_27119099 0.21 ENST00000402550.5
ENST00000402394.6
cell growth regulator with EF-hand domain 1
chr17_+_76737387 0.21 ENST00000590393.1
ENST00000355954.7
ENST00000586689.5
ENST00000587661.5
ENST00000593181.5
ENST00000336509.8
major facilitator superfamily domain containing 11
chr3_+_37861926 0.21 ENST00000443503.6
CTD small phosphatase like
chr14_+_104138578 0.21 ENST00000423312.7
kinesin family member 26A
chr22_+_46335768 0.21 ENST00000642923.1
tRNA mitochondrial 2-thiouridylase
chr2_+_11133119 0.21 ENST00000381585.8
ENST00000405022.3
chromosome 2 open reading frame 50
chr8_+_21919648 0.21 ENST00000252512.14
exportin 7
chr20_+_35615812 0.21 ENST00000679710.1
ENST00000374273.8
sperm associated antigen 4
chr4_+_1011595 0.21 ENST00000510644.6
fibroblast growth factor receptor like 1
chr14_-_100375602 0.20 ENST00000553395.5
ENST00000553545.5
ENST00000344102.9
ENST00000556338.5
ENST00000553934.1
tryptophanyl-tRNA synthetase 1
chr20_-_57711536 0.20 ENST00000265626.8
prostate transmembrane protein, androgen induced 1
chr19_+_676385 0.20 ENST00000166139.9
follistatin like 3
chr17_-_75182536 0.20 ENST00000578238.2
small ubiquitin like modifier 2
chr16_-_8868343 0.20 ENST00000562843.5
ENST00000561530.5
ENST00000396593.6
calcium regulated heat stable protein 1
chr7_+_80133830 0.20 ENST00000648098.1
ENST00000648476.1
ENST00000648412.1
ENST00000648953.1
ENST00000648306.1
ENST00000648832.1
ENST00000648877.1
ENST00000442586.2
ENST00000649487.1
ENST00000649267.1
G protein subunit alpha i1
chr6_-_110815152 0.19 ENST00000413605.6
cyclin dependent kinase 19
chr17_+_50548041 0.19 ENST00000634597.1
spermatogenesis associated 20
chr20_+_43514492 0.19 ENST00000373135.8
ENST00000373134.5
L3MBTL histone methyl-lysine binding protein 1
chr15_-_82709823 0.19 ENST00000666973.1
ENST00000664460.1
ENST00000669930.1
adaptor related protein complex 3 subunit beta 2
chr3_-_123585013 0.19 ENST00000383657.10
3-hydroxyacyl-CoA dehydratase 2
chr7_-_149773548 0.19 ENST00000302017.4
zinc finger protein 467
chr3_-_71753582 0.19 ENST00000295612.7
eukaryotic translation initiation factor 4E family member 3
chr7_-_151187212 0.19 ENST00000420175.3
ENST00000275838.5
ankyrin repeat and SOCS box containing 10
chr11_+_64234569 0.18 ENST00000309422.7
ENST00000426086.3
vascular endothelial growth factor B
chr14_+_95876762 0.18 ENST00000503525.2
TCL1 upstream neural differentiation-associated RNA
chrX_+_154585120 0.18 ENST00000593606.3
ENST00000599837.3
cancer/testis antigen 1A
chr21_+_36135071 0.18 ENST00000290354.6
carbonyl reductase 3
chr14_+_100381974 0.18 ENST00000542471.2
WD repeat domain 25
chr5_+_41925223 0.18 ENST00000296812.6
ENST00000281623.8
ENST00000509134.1
F-box protein 4
chr17_-_15999634 0.18 ENST00000472495.5
zinc finger SWIM-type containing 7
chr6_-_36839434 0.18 ENST00000244751.7
ENST00000633280.1
copine 5
chr11_-_6320494 0.18 ENST00000303927.4
ENST00000530979.1
caveolae associated protein 3
chr10_-_77637633 0.18 ENST00000638223.1
ENST00000639544.1
ENST00000640807.1
ENST00000434208.6
ENST00000626620.3
ENST00000638575.1
ENST00000638759.1
potassium calcium-activated channel subfamily M alpha 1
chr1_-_205680486 0.18 ENST00000367145.4
solute carrier family 45 member 3
chr16_-_8868687 0.18 ENST00000618335.4
ENST00000570125.5
calcium regulated heat stable protein 1
chr5_+_127290785 0.18 ENST00000503335.7
multiple EGF like domains 10
chr19_+_1266653 0.18 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr11_-_119340816 0.18 ENST00000528368.3
C1q and TNF related 5
chr20_-_64049631 0.17 ENST00000340356.9
SRY-box transcription factor 18
chr6_-_89412219 0.17 ENST00000369415.9
Ras related GTP binding D
chr1_+_32741779 0.17 ENST00000401073.7
KIAA1522
chr11_+_87037915 0.17 ENST00000526733.5
ENST00000305494.6
ENST00000532959.5
transmembrane protein 135
chr7_+_150405146 0.17 ENST00000498682.3
ENST00000641717.1
novel zinc finger protein
chr22_+_43110741 0.17 ENST00000216115.3
BCL2 interacting killer
chrX_+_71283577 0.17 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
non-POU domain containing octamer binding
chr15_-_70096260 0.16 ENST00000558201.5
TLE family member 3, transcriptional corepressor
chr3_-_133895753 0.16 ENST00000460865.3
RAB6B, member RAS oncogene family
chr14_+_91114431 0.16 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr19_-_3062464 0.16 ENST00000327141.9
TLE family member 5, transcriptional modulator
chr6_-_89412069 0.16 ENST00000359203.3
Ras related GTP binding D
chr19_-_291365 0.16 ENST00000591572.2
ENST00000269812.7
ENST00000633125.1
ENST00000434325.7
phospholipid phosphatase 2
chr21_+_41168142 0.16 ENST00000330333.11
beta-secretase 2
chr17_-_15999589 0.16 ENST00000486655.5
zinc finger SWIM-type containing 7
chr16_+_3012915 0.16 ENST00000445369.3
claudin 9
chr6_-_693070 0.16 ENST00000443083.5
ENST00000230449.9
exocyst complex component 2
chrX_+_136497079 0.16 ENST00000535601.5
ENST00000448450.5
ENST00000425695.5
HIV-1 Tat specific factor 1
chr17_-_78128778 0.16 ENST00000589553.5
transmembrane channel like 6
chr7_-_150323489 0.16 ENST00000683684.1
ENST00000478393.5
actin related protein 3C
chr19_-_42302766 0.16 ENST00000595530.5
ENST00000538771.5
ENST00000601865.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr19_-_291132 0.16 ENST00000327790.7
phospholipid phosphatase 2
chr3_-_177197248 0.16 ENST00000427349.5
ENST00000352800.10
TBL1X receptor 1
chr10_+_133087883 0.16 ENST00000392607.8
adhesion G protein-coupled receptor A1
chr2_+_42568510 0.16 ENST00000407270.7
metastasis associated 1 family member 3
chr1_-_182672232 0.16 ENST00000508450.5
regulator of G protein signaling 8
chr18_+_48539112 0.15 ENST00000382998.8
cap binding complex dependent translation initiation factor
chr9_+_113150991 0.15 ENST00000259392.8
solute carrier family 31 member 2
chr17_+_40443441 0.15 ENST00000269593.5
insulin like growth factor binding protein 4
chr14_+_91114364 0.15 ENST00000518868.5
D-glutamate cyclase
chr2_+_233729042 0.15 ENST00000482026.6
UDP glucuronosyltransferase family 1 member A3
chr11_-_65900375 0.15 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr10_-_87094761 0.15 ENST00000684338.1
ENST00000684201.1
ENST00000277865.5
glutamate dehydrogenase 1
chr16_+_1078781 0.14 ENST00000293897.5
somatostatin receptor 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.7 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 0.6 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 0.6 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.2 0.7 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.2 14.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.7 GO:0015692 lead ion transport(GO:0015692)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.3 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.3 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.2 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.3 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868) negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0006113 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 1.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.4 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 0.7 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.2 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.4 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:0048865 stem cell fate commitment(GO:0048865)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.2 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.8 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.4 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 1.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0061011 hepatic duct development(GO:0061011)
0.0 0.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 1.3 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:1902996 regulation of neuronal signal transduction(GO:1902847) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.7 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0052205 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0030167 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.0 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.0 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.1 GO:0010044 response to aluminum ion(GO:0010044)
0.0 0.8 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 0.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 14.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.4 GO:0097196 Shu complex(GO:0097196)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 0.8 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0043273 CTPase activity(GO:0043273)
0.1 0.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.1 0.2 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.1 0.3 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions