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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZNF274

Z-value: 0.37

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Transcription factors associated with ZNF274

Gene Symbol Gene ID Gene Info
ZNF274
ENSG00000171606.18 ZNF274

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF274hg38_v1_chr19_+_58183029_581831310.116.0e-01Click!

Activity profile of ZNF274 motif

Sorted Z-values of ZNF274 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF274

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_4752565 3.28 ENST00000588099.1
ENST00000588942.1
ENSG00000266994.1
ZNF500
novel transcript
zinc finger protein 500
chr2_+_236569817 1.20 ENST00000272928.4
ACKR3
atypical chemokine receptor 3
chr6_+_31586124 0.53 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
LST1
leukocyte specific transcript 1
chr1_-_15944348 0.48 ENST00000444358.1
ZBTB17
zinc finger and BTB domain containing 17
chr19_+_39704461 0.43 ENST00000360675.7
ENST00000392052.8
ENST00000601802.1
LGALS14
galectin 14
chr6_+_31586269 0.40 ENST00000438075.7
LST1
leukocyte specific transcript 1
chr20_-_1657762 0.37 ENST00000303415.7
ENST00000381583.6
SIRPG
signal regulatory protein gamma
chr15_+_88621290 0.33 ENST00000332810.4
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr20_-_1657714 0.32 ENST00000216927.4
ENST00000344103.8
SIRPG
signal regulatory protein gamma
chr11_+_55885920 0.28 ENST00000244891.3
TRIM51
tripartite motif-containing 51
chr19_+_6135635 0.28 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr22_+_23696400 0.24 ENST00000452208.1
RGL4
ral guanine nucleotide dissociation stimulator like 4
chr6_-_83431038 0.21 ENST00000369705.4
ME1
malic enzyme 1
chr18_+_9103959 0.19 ENST00000400033.1
NDUFV2
NADH:ubiquinone oxidoreductase core subunit V2
chr3_+_50246888 0.19 ENST00000451956.1
GNAI2
G protein subunit alpha i2
chr10_+_69278492 0.18 ENST00000643399.2
HK1
hexokinase 1
chr14_-_23578756 0.17 ENST00000397118.7
ENST00000356300.9
JPH4
junctophilin 4
chr6_+_36197356 0.17 ENST00000446974.1
ENST00000454960.1
BRPF3
bromodomain and PHD finger containing 3
chr6_+_125153649 0.16 ENST00000304877.17
ENST00000368402.9
ENST00000368388.6
ENST00000534000.6
TPD52L1
TPD52 like 1
chr1_+_44739825 0.16 ENST00000372224.9
KIF2C
kinesin family member 2C
chr11_+_89926762 0.15 ENST00000526396.3
TRIM49D2
tripartite motif containing 49D2
chr21_+_39451963 0.14 ENST00000333634.10
SH3BGR
SH3 domain binding glutamate rich protein
chr19_+_15793951 0.14 ENST00000308940.8
OR10H5
olfactory receptor family 10 subfamily H member 5
chr21_+_39452077 0.14 ENST00000452550.5
SH3BGR
SH3 domain binding glutamate rich protein
chr5_-_173616588 0.14 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
BOD1
biorientation of chromosomes in cell division 1
chr6_-_127459364 0.12 ENST00000487331.2
ENST00000483725.8
KIAA0408
KIAA0408
chr12_-_54259531 0.11 ENST00000550411.5
ENST00000439541.6
CBX5
chromobox 5
chr6_+_30720335 0.10 ENST00000327892.13
TUBB
tubulin beta class I
chr1_-_156282799 0.10 ENST00000361813.5
SMG5
SMG5 nonsense mediated mRNA decay factor
chr12_-_49187369 0.10 ENST00000547939.6
TUBA1A
tubulin alpha 1a
chr19_+_45995445 0.09 ENST00000536603.5
ENST00000595358.5
ENST00000594672.5
CCDC61
coiled-coil domain containing 61
chr11_-_41459592 0.08 ENST00000528697.6
ENST00000530763.5
LRRC4C
leucine rich repeat containing 4C
chr5_+_122129533 0.08 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
ZNF474
zinc finger protein 474
chr14_+_21941122 0.08 ENST00000390441.2
TRAV9-2
T cell receptor alpha variable 9-2
chr9_-_33473884 0.07 ENST00000297990.9
ENST00000353159.6
ENST00000379471.3
NOL6
nucleolar protein 6
chr19_-_19663664 0.06 ENST00000357324.11
ATP13A1
ATPase 13A1
chr3_+_128153422 0.06 ENST00000254730.11
ENST00000483457.1
EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA specific
chr12_+_49741544 0.06 ENST00000549966.5
ENST00000547832.5
ENST00000547187.5
ENST00000548894.5
ENST00000546914.5
ENST00000552699.5
ENST00000267115.10
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr7_+_30752127 0.06 ENST00000013222.5
ENST00000409539.1
INMT
indolethylamine N-methyltransferase
chr16_+_29807536 0.04 ENST00000567444.5
MAZ
MYC associated zinc finger protein
chrX_+_120604199 0.04 ENST00000371315.3
MCTS1
MCTS1 re-initiation and release factor
chrX_-_70260199 0.03 ENST00000374519.4
P2RY4
pyrimidinergic receptor P2Y4
chr18_+_9885964 0.03 ENST00000357775.6
ENST00000306084.6
TXNDC2
thioredoxin domain containing 2
chr1_-_113871665 0.02 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
PTPN22
protein tyrosine phosphatase non-receptor type 22
chr16_+_29808125 0.02 ENST00000568282.1
MAZ
MYC associated zinc finger protein
chr3_+_102435015 0.02 ENST00000306176.5
ENST00000466937.2
ZPLD1
zona pellucida like domain containing 1
chr7_-_87600873 0.01 ENST00000622132.5
ABCB1
ATP binding cassette subfamily B member 1
chr11_-_10568571 0.00 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr16_+_29808051 0.00 ENST00000568544.5
ENST00000569978.1
MAZ
MYC associated zinc finger protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741) regulation of NADP metabolic process(GO:1902031)
0.0 0.4 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 1.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.5 GO:0007398 ectoderm development(GO:0007398)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions