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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZNF423

Z-value: 0.99

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Transcription factors associated with ZNF423

Gene Symbol Gene ID Gene Info
ZNF423
ENSG00000102935.12 ZNF423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF423hg38_v1_chr16_-_49856105_49856119-0.663.0e-04Click!

Activity profile of ZNF423 motif

Sorted Z-values of ZNF423 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF423

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_11587162 4.96 ENST00000570904.5
ENST00000574701.5
LITAF
lipopolysaccharide induced TNF factor
chr17_+_79024142 4.00 ENST00000579760.6
ENST00000339142.6
C1QTNF1
C1q and TNF related 1
chr17_+_79024243 3.97 ENST00000311661.4
C1QTNF1
C1q and TNF related 1
chr16_-_11587450 3.41 ENST00000571688.5
LITAF
lipopolysaccharide induced TNF factor
chr12_-_49707368 3.29 ENST00000352151.9
ENST00000335154.10
FMNL3
formin like 3
chr12_-_57129001 2.85 ENST00000556155.5
STAT6
signal transducer and activator of transcription 6
chr12_-_49707220 2.62 ENST00000550488.5
FMNL3
formin like 3
chr4_-_119628007 2.50 ENST00000420633.1
ENST00000394439.5
PDE5A
phosphodiesterase 5A
chr8_-_79767843 2.40 ENST00000337919.9
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr8_-_79767462 2.37 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr5_+_136049513 2.08 ENST00000514554.5
TGFBI
transforming growth factor beta induced
chr7_-_19145306 1.94 ENST00000275461.3
FERD3L
Fer3 like bHLH transcription factor
chr1_-_203086001 1.93 ENST00000241651.5
MYOG
myogenin
chr16_+_2988256 1.82 ENST00000573315.2
LINC00514
long intergenic non-protein coding RNA 514
chr5_-_139482341 1.79 ENST00000651699.1
STING1
stimulator of interferon response cGAMP interactor 1
chr21_-_17612842 1.64 ENST00000339775.10
ENST00000348354.7
BTG3
BTG anti-proliferation factor 3
chr10_-_119536533 1.60 ENST00000392865.5
RGS10
regulator of G protein signaling 10
chr16_+_30664334 1.51 ENST00000287468.5
FBRS
fibrosin
chr2_+_27496830 1.49 ENST00000264717.7
GCKR
glucokinase regulator
chr10_-_98268186 1.43 ENST00000260702.4
LOXL4
lysyl oxidase like 4
chr19_+_45079195 1.40 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
GEMIN7
MARK4
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr11_-_61891381 1.34 ENST00000525588.5
FADS3
fatty acid desaturase 3
chr22_-_37427433 1.30 ENST00000452946.1
ENST00000402918.7
ELFN2
ELFN2
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr7_-_23014074 1.27 ENST00000409763.1
ENST00000679826.1
ENST00000409923.5
ENST00000681766.1
FAM126A
family with sequence similarity 126 member A
chr19_+_14433284 1.24 ENST00000242783.11
PKN1
protein kinase N1
chr4_-_119627631 1.22 ENST00000264805.9
PDE5A
phosphodiesterase 5A
chr5_+_53480619 1.15 ENST00000396947.7
ENST00000256759.8
FST
follistatin
chr11_-_61891534 1.13 ENST00000278829.7
FADS3
fatty acid desaturase 3
chr6_+_11093753 1.13 ENST00000416247.4
SMIM13
small integral membrane protein 13
chr7_-_23014099 1.12 ENST00000432176.7
ENST00000440481.6
FAM126A
family with sequence similarity 126 member A
chr16_+_27313879 1.05 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
IL4R
interleukin 4 receptor
chrX_+_30247139 0.99 ENST00000397548.4
MAGEB1
MAGE family member B1
chr20_+_33993904 0.98 ENST00000246194.8
RALY
RALY heterogeneous nuclear ribonucleoprotein
chr1_+_1512137 0.97 ENST00000378756.8
ENST00000378755.9
ATAD3A
ATPase family AAA domain containing 3A
chr22_-_38088915 0.96 ENST00000428572.1
BAIAP2L2
BAR/IMD domain containing adaptor protein 2 like 2
chr6_+_109440695 0.94 ENST00000258052.8
SMPD2
sphingomyelin phosphodiesterase 2
chr9_+_109780292 0.93 ENST00000374530.7
PALM2AKAP2
PALM2 and AKAP2 fusion
chr15_-_75368578 0.91 ENST00000569482.5
ENST00000565683.5
ENST00000561615.1
ENST00000563622.5
ENST00000568374.5
ENST00000267978.10
ENST00000566256.5
MAN2C1
mannosidase alpha class 2C member 1
chr19_-_49867251 0.86 ENST00000631020.2
ENST00000596014.5
ENST00000636994.1
PNKP
polynucleotide kinase 3'-phosphatase
chr1_+_1471751 0.84 ENST00000673477.1
ENST00000308647.8
ATAD3B
ATPase family AAA domain containing 3B
chr5_+_171309239 0.81 ENST00000296921.6
TLX3
T cell leukemia homeobox 3
chr12_+_52079700 0.80 ENST00000546390.2
SMIM41
small integral membrane protein 41
chr19_+_35533436 0.79 ENST00000222286.9
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr9_+_132162045 0.77 ENST00000393229.4
NTNG2
netrin G2
chr1_+_26993684 0.76 ENST00000522111.3
TRNP1
TMF1 regulated nuclear protein 1
chr11_-_61295289 0.76 ENST00000335613.10
VWCE
von Willebrand factor C and EGF domains
chr8_+_30384511 0.76 ENST00000339877.8
ENST00000320203.8
ENST00000287771.9
ENST00000397323.9
RBPMS
RNA binding protein, mRNA processing factor
chr7_-_100894233 0.71 ENST00000426415.5
ENST00000430554.1
ENST00000412389.5
ACHE
acetylcholinesterase (Cartwright blood group)
chr19_-_10339610 0.69 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr7_-_103989649 0.68 ENST00000428762.6
RELN
reelin
chr22_-_42649332 0.67 ENST00000352397.10
CYB5R3
cytochrome b5 reductase 3
chr8_+_22165358 0.67 ENST00000306349.13
ENST00000306385.10
BMP1
bone morphogenetic protein 1
chr11_-_30586866 0.66 ENST00000528686.2
MPPED2
metallophosphoesterase domain containing 2
chr1_-_6180265 0.64 ENST00000262450.8
CHD5
chromodomain helicase DNA binding protein 5
chrX_+_137566119 0.64 ENST00000287538.10
ZIC3
Zic family member 3
chr16_-_70685791 0.60 ENST00000616026.4
MTSS2
MTSS I-BAR domain containing 2
chr17_+_7438267 0.58 ENST00000575235.5
FGF11
fibroblast growth factor 11
chr10_+_84173793 0.56 ENST00000372126.4
C10orf99
chromosome 10 open reading frame 99
chr8_+_22565655 0.55 ENST00000523965.5
SORBS3
sorbin and SH3 domain containing 3
chr22_+_35257452 0.54 ENST00000420166.5
ENST00000216106.6
ENST00000455359.5
HMGXB4
HMG-box containing 4
chr5_+_169583636 0.54 ENST00000506574.5
ENST00000515224.5
ENST00000629457.2
ENST00000508247.5
ENST00000265295.9
ENST00000513941.5
SPDL1
spindle apparatus coiled-coil protein 1
chr6_+_33621313 0.53 ENST00000605930.3
ITPR3
inositol 1,4,5-trisphosphate receptor type 3
chr8_+_22165140 0.52 ENST00000397814.7
ENST00000354870.5
BMP1
bone morphogenetic protein 1
chr9_+_113876282 0.52 ENST00000374126.9
ENST00000615615.4
ENST00000288466.11
ZNF618
zinc finger protein 618
chr6_-_35512882 0.51 ENST00000229771.11
TULP1
TUB like protein 1
chr12_+_57128656 0.51 ENST00000338962.8
LRP1
LDL receptor related protein 1
chr19_+_4279247 0.50 ENST00000543264.7
SHD
Src homology 2 domain containing transforming protein D
chr18_-_5543988 0.50 ENST00000341928.7
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr6_-_35512863 0.49 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TULP1
TUB like protein 1
chr3_-_196082078 0.49 ENST00000360110.9
ENST00000392396.7
ENST00000420415.5
TFRC
transferrin receptor
chr6_-_31112566 0.48 ENST00000259870.4
C6orf15
chromosome 6 open reading frame 15
chr20_+_44885679 0.48 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chr10_+_123154768 0.47 ENST00000407911.2
BUB3
BUB3 mitotic checkpoint protein
chr12_-_54385727 0.46 ENST00000551109.5
ENST00000546970.5
ZNF385A
zinc finger protein 385A
chr2_-_120223371 0.42 ENST00000426077.3
TMEM185B
transmembrane protein 185B
chr20_+_33993646 0.42 ENST00000375114.7
ENST00000448364.5
RALY
RALY heterogeneous nuclear ribonucleoprotein
chr19_-_11481044 0.42 ENST00000359227.8
ELAVL3
ELAV like RNA binding protein 3
chr16_+_3046552 0.41 ENST00000336577.9
MMP25
matrix metallopeptidase 25
chr19_-_42242526 0.41 ENST00000222330.8
ENST00000676537.1
GSK3A
glycogen synthase kinase 3 alpha
chr4_-_20984011 0.40 ENST00000382149.9
KCNIP4
potassium voltage-gated channel interacting protein 4
chr7_+_20330893 0.39 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr20_+_31475278 0.39 ENST00000201979.3
REM1
RRAD and GEM like GTPase 1
chr10_+_123154414 0.39 ENST00000368858.9
BUB3
BUB3 mitotic checkpoint protein
chr11_-_30586344 0.38 ENST00000358117.10
MPPED2
metallophosphoesterase domain containing 2
chr19_-_55599493 0.37 ENST00000221665.5
ENST00000592585.1
FIZ1
FLT3 interacting zinc finger 1
chr10_+_123154364 0.36 ENST00000368859.6
ENST00000368865.9
BUB3
BUB3 mitotic checkpoint protein
chr20_+_23035312 0.36 ENST00000255008.5
SSTR4
somatostatin receptor 4
chr17_-_44376169 0.36 ENST00000587295.5
ITGA2B
integrin subunit alpha 2b
chr10_+_133527355 0.35 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
CYP2E1
cytochrome P450 family 2 subfamily E member 1
chr5_-_176630517 0.35 ENST00000393693.7
ENST00000614675.4
SNCB
synuclein beta
chr11_-_107858777 0.35 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr19_-_15200902 0.34 ENST00000601011.1
ENST00000263388.7
NOTCH3
notch receptor 3
chr2_+_170929198 0.34 ENST00000234160.5
GORASP2
golgi reassembly stacking protein 2
chr2_+_227616998 0.34 ENST00000641801.1
SCYGR4
small cysteine and glycine repeat containing 4
chr6_-_90586883 0.34 ENST00000369325.7
ENST00000369327.7
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr16_+_283157 0.33 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
PDIA2
protein disulfide isomerase family A member 2
chr19_-_38224215 0.33 ENST00000355526.10
ENST00000420980.7
ENST00000614244.4
DPF1
double PHD fingers 1
chr5_-_176630364 0.32 ENST00000310112.7
SNCB
synuclein beta
chr1_-_228109255 0.32 ENST00000483159.1
ENST00000366744.5
ENST00000348259.9
ENST00000495434.1
ENST00000295008.8
ENST00000366731.9
ENST00000366746.7
ENST00000366747.7
ENST00000336520.8
ENST00000391867.8
ENST00000457264.5
ENST00000464148.2
ENST00000336300.9
ENST00000430433.5
MRPL55
mitochondrial ribosomal protein L55
chr19_+_4279285 0.31 ENST00000599689.1
SHD
Src homology 2 domain containing transforming protein D
chr9_+_98807619 0.31 ENST00000375011.4
GALNT12
polypeptide N-acetylgalactosaminyltransferase 12
chr6_+_30163188 0.31 ENST00000619857.4
TRIM15
tripartite motif containing 15
chr11_-_44950151 0.30 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr7_-_5530581 0.30 ENST00000676397.1
ENST00000645576.1
ENST00000674681.1
ENST00000646664.1
ENST00000493945.6
ENST00000676319.1
ENST00000473257.3
ENST00000647275.1
ENST00000432588.6
ACTB
actin beta
chr10_-_73495966 0.28 ENST00000342558.3
ENST00000360663.10
ENST00000394828.6
ENST00000394829.6
PPP3CB
protein phosphatase 3 catalytic subunit beta
chr19_-_4066892 0.28 ENST00000322357.9
ZBTB7A
zinc finger and BTB domain containing 7A
chr19_+_48393657 0.28 ENST00000263269.4
GRIN2D
glutamate ionotropic receptor NMDA type subunit 2D
chr6_-_90587018 0.26 ENST00000369332.7
ENST00000369329.8
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr7_+_29194757 0.25 ENST00000222792.11
CHN2
chimerin 2
chr9_+_128787331 0.25 ENST00000223865.8
TBC1D13
TBC1 domain family member 13
chr7_+_151051201 0.25 ENST00000490540.1
ASIC3
acid sensing ion channel subunit 3
chr8_+_22565236 0.24 ENST00000523900.5
SORBS3
sorbin and SH3 domain containing 3
chr20_-_31475125 0.23 ENST00000317676.3
DEFB124
defensin beta 124
chr2_-_206086057 0.23 ENST00000403263.6
INO80D
INO80 complex subunit D
chr6_+_30163541 0.23 ENST00000376694.9
TRIM15
tripartite motif containing 15
chr1_+_26317950 0.22 ENST00000374213.3
CD52
CD52 molecule
chr1_-_101996919 0.22 ENST00000370103.9
OLFM3
olfactomedin 3
chr17_+_6444441 0.22 ENST00000250056.12
ENST00000571373.5
ENST00000570337.6
ENST00000572595.6
ENST00000572447.6
ENST00000576056.5
PIMREG
PICALM interacting mitotic regulator
chrX_+_49171889 0.22 ENST00000376327.6
PLP2
proteolipid protein 2
chr1_-_32901330 0.21 ENST00000329151.5
ENST00000373463.8
TMEM54
transmembrane protein 54
chr7_-_100158679 0.21 ENST00000456769.5
ENST00000316937.8
TRAPPC14
trafficking protein particle complex 14
chr12_+_109713817 0.20 ENST00000538780.2
FAM222A
family with sequence similarity 222 member A
chr9_-_128724088 0.20 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
ZDHHC12
zinc finger DHHC-type palmitoyltransferase 12
chr11_-_1036706 0.20 ENST00000421673.7
MUC6
mucin 6, oligomeric mucus/gel-forming
chr9_-_37904085 0.20 ENST00000377716.6
ENST00000242275.7
SLC25A51
solute carrier family 25 member 51
chr16_+_2964216 0.19 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
KREMEN2
kringle containing transmembrane protein 2
chr11_-_44950867 0.18 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
TP53I11
tumor protein p53 inducible protein 11
chr11_-_63015831 0.17 ENST00000430500.6
ENST00000336232.7
SLC22A8
solute carrier family 22 member 8
chr1_-_165445220 0.17 ENST00000619224.1
RXRG
retinoid X receptor gamma
chrX_+_49171918 0.15 ENST00000376322.7
PLP2
proteolipid protein 2
chr19_+_45251363 0.14 ENST00000620044.4
MARK4
microtubule affinity regulating kinase 4
chr9_-_127980976 0.14 ENST00000373095.6
FAM102A
family with sequence similarity 102 member A
chr13_+_51222391 0.14 ENST00000322475.13
FAM124A
family with sequence similarity 124 member A
chr11_-_44950839 0.14 ENST00000395648.7
ENST00000531928.6
TP53I11
tumor protein p53 inducible protein 11
chr19_+_45251249 0.14 ENST00000262891.9
ENST00000300843.8
MARK4
microtubule affinity regulating kinase 4
chr1_-_165445088 0.13 ENST00000359842.10
RXRG
retinoid X receptor gamma
chr10_+_125896549 0.11 ENST00000368693.6
FANK1
fibronectin type III and ankyrin repeat domains 1
chr1_-_155207886 0.10 ENST00000368378.7
ENST00000541990.5
ENST00000457183.6
ENST00000541576.5
THBS3
thrombospondin 3
chr17_-_81239025 0.09 ENST00000637944.2
TEPSIN
TEPSIN adaptor related protein complex 4 accessory protein
chr6_-_109440504 0.09 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
PPIL6
peptidylprolyl isomerase like 6
chr3_+_184338826 0.09 ENST00000453072.5
FAM131A
family with sequence similarity 131 member A
chr3_+_138349209 0.08 ENST00000474559.1
MRAS
muscle RAS oncogene homolog
chr7_+_20330678 0.07 ENST00000537992.5
ITGB8
integrin subunit beta 8
chr20_-_25082131 0.04 ENST00000429762.7
ENST00000444511.6
ENST00000376707.4
ENST00000376709.9
VSX1
visual system homeobox 1
chr14_-_93115812 0.03 ENST00000553452.5
ITPK1
inositol-tetrakisphosphate 1-kinase
chr9_+_136982993 0.02 ENST00000408973.3
LCNL1
lipocalin like 1
chr17_+_2337622 0.02 ENST00000574563.5
SGSM2
small G protein signaling modulator 2
chr9_-_127897399 0.02 ENST00000542456.5
ENST00000373141.5
ST6GALNAC6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr15_-_41230697 0.02 ENST00000314992.9
ENST00000558396.1
ENST00000458580.7
EXD1
exonuclease 3'-5' domain containing 1
chr9_-_96619378 0.01 ENST00000375240.7
ENST00000463569.5
CDC14B
cell division cycle 14B
chrX_+_106920393 0.00 ENST00000336803.2
CLDN2
claudin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0061027 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
1.1 8.0 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 2.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.6 1.9 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.5 3.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 1.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 1.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.2 1.9 GO:0033504 floor plate development(GO:0033504)
0.2 0.7 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 0.7 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.2 8.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 1.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.5 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.9 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.9 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.4 GO:0006258 UDP-glucose catabolic process(GO:0006258) negative regulation of type B pancreatic cell development(GO:2000077)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.4 GO:0010193 response to ozone(GO:0010193)
0.1 1.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926) positive regulation of hair follicle development(GO:0051798)
0.1 1.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.9 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 1.2 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.8 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 1.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.7 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.5 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 2.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.4 GO:0060022 hard palate development(GO:0060022)
0.0 5.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 2.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.2 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.7 GO:0042417 dopamine metabolic process(GO:0042417)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.4 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.4 1.2 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.2 0.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 8.0 GO:0005581 collagen trimer(GO:0005581)
0.1 1.0 GO:0071439 clathrin complex(GO:0071439)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0035939 microsatellite binding(GO:0035939)
0.4 1.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.3 1.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.9 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 5.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.5 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.2 0.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 8.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.1 3.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.5 GO:0050815 phosphoserine binding(GO:0050815)
0.1 8.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.9 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.2 GO:0048185 activin binding(GO:0048185)
0.1 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:1903136 cuprous ion binding(GO:1903136)
0.0 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 1.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 4.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 9.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.9 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 4.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.2 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix