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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZNF691

Z-value: 0.36

Motif logo

Transcription factors associated with ZNF691

Gene Symbol Gene ID Gene Info
ENSG00000164011.18 ZNF691

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF691hg38_v1_chr1_+_42846573_42846640-0.311.3e-01Click!

Activity profile of ZNF691 motif

Sorted Z-values of ZNF691 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF691

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_5389377 0.48 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr16_+_56336805 0.36 ENST00000564727.2
G protein subunit alpha o1
chr19_+_49581304 0.31 ENST00000246794.10
proline rich and Gla domain 2
chr16_+_56336727 0.29 ENST00000568375.2
G protein subunit alpha o1
chr9_+_137077467 0.28 ENST00000409858.8
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
chr16_+_56336767 0.27 ENST00000640469.1
G protein subunit alpha o1
chrX_-_63351308 0.26 ENST00000374884.3
spindlin family member 4
chr17_+_77405070 0.25 ENST00000585930.5
septin 9
chr2_-_74441882 0.21 ENST00000272430.10
rhotekin
chr11_+_44726811 0.19 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chr10_+_127907036 0.18 ENST00000254667.8
ENST00000442830.5
protein tyrosine phosphatase receptor type E
chr2_-_109613835 0.18 ENST00000415095.5
ENST00000437928.5
ENST00000493445.5
ENST00000397714.6
ENST00000461295.1
ENST00000397712.7
septin 10
chr9_+_136658854 0.17 ENST00000371699.5
EGF like domain multiple 7
chr17_+_45844875 0.17 ENST00000329196.7
signal peptide peptidase like 2C
chr12_-_51324091 0.17 ENST00000604560.6
bridging integrator 2
chr2_-_127642131 0.17 ENST00000426981.5
LIM zinc finger domain containing 2
chr14_-_20802402 0.17 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr6_-_89819699 0.16 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
midasin AAA ATPase 1
chr14_-_20802836 0.16 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr12_+_100503352 0.16 ENST00000551379.5
ENST00000188403.7
nuclear receptor subfamily 1 group H member 4
chr3_-_49869886 0.16 ENST00000296471.11
ENST00000488336.5
ENST00000477224.6
ENST00000467248.5
ENST00000466940.5
ENST00000463537.5
ENST00000480398.2
CaM kinase like vesicle associated
chr12_-_51324164 0.16 ENST00000615107.6
bridging integrator 2
chr3_+_129974712 0.16 ENST00000302649.4
thyrotropin releasing hormone
chr12_-_51324138 0.16 ENST00000452142.7
bridging integrator 2
chr22_+_22880706 0.16 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr20_-_35147285 0.15 ENST00000374491.3
ENST00000374492.8
ER degradation enhancing alpha-mannosidase like protein 2
chr6_-_119149124 0.15 ENST00000368475.8
family with sequence similarity 184 member A
chr3_+_129974680 0.15 ENST00000507066.1
thyrotropin releasing hormone
chr12_-_132687307 0.14 ENST00000535270.5
ENST00000320574.10
DNA polymerase epsilon, catalytic subunit
chr5_-_132556809 0.13 ENST00000450655.1
interleukin 5
chr15_-_25863304 0.13 ENST00000555815.6
ENST00000673716.1
ATPase phospholipid transporting 10A (putative)
chr11_-_36598221 0.13 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chrX_+_103710907 0.12 ENST00000319560.7
transmembrane protein 31
chr2_-_109614143 0.12 ENST00000356688.8
septin 10
chr6_+_28525877 0.12 ENST00000412168.7
glutathione peroxidase 5
chr7_+_134891400 0.12 ENST00000393118.6
caldesmon 1
chr19_+_49877660 0.12 ENST00000535102.6
TBC1 domain family member 17
chr16_+_760728 0.12 ENST00000545450.7
ENST00000563941.5
ENST00000566549.5
mesothelin
chr16_+_84294823 0.12 ENST00000568638.1
WAP four-disulfide core domain 1
chr4_+_157076119 0.12 ENST00000541722.5
ENST00000264428.9
ENST00000512619.5
glycine receptor beta
chr21_-_46155567 0.12 ENST00000291670.9
ENST00000397748.5
ENST00000397743.1
ENST00000397746.8
formimidoyltransferase cyclodeaminase
chr16_+_84294853 0.11 ENST00000219454.10
WAP four-disulfide core domain 1
chr12_-_51324652 0.11 ENST00000544402.5
bridging integrator 2
chr10_-_89251768 0.11 ENST00000336233.10
lipase A, lysosomal acid type
chr2_-_85561513 0.11 ENST00000430215.7
gamma-glutamyl carboxylase
chrX_-_104013708 0.10 ENST00000217926.7
H2B.W histone 1
chr12_-_23584600 0.10 ENST00000396007.6
SRY-box transcription factor 5
chr6_-_158819355 0.10 ENST00000367075.4
ezrin
chr13_-_52129051 0.10 ENST00000652119.1
ENST00000647945.1
ENST00000355568.8
NIMA related kinase 5
chr11_-_57381146 0.10 ENST00000287143.2
proteoglycan 3, pro eosinophil major basic protein 2
chr12_+_94262521 0.10 ENST00000545312.1
plexin C1
chr18_+_11751467 0.09 ENST00000535121.5
G protein subunit alpha L
chr21_+_14216145 0.09 ENST00000400577.4
RNA binding motif protein 11
chr6_-_144008396 0.09 ENST00000354765.6
ENST00000416623.5
ENST00000649211.1
PLAG1 like zinc finger 1
chr14_+_102922639 0.09 ENST00000299155.10
amnion associated transmembrane protein
chr15_-_49620747 0.09 ENST00000559905.5
ENST00000560246.1
ENST00000299338.11
ENST00000558594.5
family with sequence similarity 227 member B
chr5_-_39074377 0.09 ENST00000514735.1
ENST00000357387.8
ENST00000296782.9
RPTOR independent companion of MTOR complex 2
chr20_+_64255728 0.08 ENST00000369758.8
ENST00000308824.11
ENST00000609372.1
ENST00000610196.1
ENST00000609764.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr18_+_11751494 0.08 ENST00000269162.9
G protein subunit alpha L
chr1_-_233295712 0.08 ENST00000258229.14
pecanex 2
chr16_+_53703963 0.08 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO alpha-ketoglutarate dependent dioxygenase
chr3_-_172523460 0.08 ENST00000420541.6
TNF superfamily member 10
chr19_-_49808639 0.08 ENST00000529634.2
fuzzy planar cell polarity protein
chr2_+_201260496 0.07 ENST00000323492.11
caspase 8
chr19_-_17821505 0.06 ENST00000598577.1
ENST00000317306.8
ENST00000379695.5
insulin like 3
chr20_-_1588632 0.06 ENST00000262929.9
ENST00000567028.5
signal regulatory protein beta 1
novel protein, SIRPB1-SIRPD readthrough
chr9_+_132878873 0.06 ENST00000356311.10
ENST00000350499.6
sperm acrosome associated 9
chr11_-_65888435 0.06 ENST00000357519.9
ENST00000533045.5
ENST00000338369.6
FGF1 intracellular binding protein
chr3_+_46370854 0.06 ENST00000292303.4
C-C motif chemokine receptor 5
chr12_-_108827384 0.06 ENST00000326470.9
slingshot protein phosphatase 1
chr16_+_85654386 0.06 ENST00000412692.5
Gse1 coiled-coil protein
chr11_+_121590388 0.06 ENST00000527934.1
sortilin related receptor 1
chr2_+_201233443 0.05 ENST00000392263.6
ENST00000264274.13
ENST00000432109.6
ENST00000264275.9
ENST00000450491.5
ENST00000440732.5
ENST00000392258.7
caspase 8
chr7_+_134891566 0.05 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chr3_+_37452121 0.05 ENST00000264741.10
integrin subunit alpha 9
chr3_-_172523423 0.05 ENST00000241261.7
TNF superfamily member 10
chr5_-_177462379 0.05 ENST00000512501.1
drebrin 1
chr9_+_132978651 0.04 ENST00000636137.1
growth factor independent 1B transcriptional repressor
chr22_-_31662180 0.04 ENST00000435900.5
phosphatidylserine decarboxylase
chrX_-_152769677 0.04 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGE family member A6
chr17_-_3513768 0.04 ENST00000570318.1
ENST00000541913.5
spermatogenesis associated 22
chr4_-_82798735 0.04 ENST00000273908.4
ENST00000319540.9
stearoyl-CoA desaturase 5
chr17_+_38752731 0.04 ENST00000619426.5
ENST00000610434.4
proteasome 20S subunit beta 3
chr17_-_28365244 0.03 ENST00000536498.5
SEBOX homeobox
chr6_-_144008364 0.03 ENST00000625622.2
PLAG1 like zinc finger 1
chr5_+_135834641 0.03 ENST00000425402.5
ENST00000681962.1
ENST00000650267.1
ENST00000510147.2
ENST00000274513.9
ENST00000433282.6
ENST00000412661.3
solute carrier family 25 member 48
chr17_-_40665121 0.03 ENST00000394052.5
keratin 222
chr3_+_37452099 0.03 ENST00000422441.5
integrin subunit alpha 9
chr9_+_132978687 0.03 ENST00000372122.4
ENST00000372123.5
growth factor independent 1B transcriptional repressor
chr14_-_91867529 0.03 ENST00000435962.7
tandem C2 domains, nuclear
chr6_+_28525986 0.03 ENST00000469384.1
glutathione peroxidase 5
chr17_+_82458733 0.03 ENST00000309794.16
ENST00000577410.2
nuclear prelamin A recognition factor
chr8_-_120445092 0.03 ENST00000518918.1
mitochondrial ribosomal protein L13
chr1_+_33472622 0.03 ENST00000361328.7
ENST00000684572.1
ENST00000373413.2
zinc finger and SCAN domain containing 20
chr1_-_147760592 0.03 ENST00000579774.3
gap junction protein alpha 5
chrX_+_78104229 0.03 ENST00000373316.5
phosphoglycerate kinase 1
chr10_+_102918344 0.03 ENST00000433628.2
cyclin and CBS domain divalent metal cation transport mediator 2
chr2_-_85668172 0.03 ENST00000428225.5
ENST00000519937.7
surfactant protein B
chr5_-_179618032 0.03 ENST00000519033.5
heterogeneous nuclear ribonucleoprotein H1
chr15_-_82349437 0.03 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
golgin A6 family like 10
chr8_+_98426943 0.03 ENST00000287042.5
potassium voltage-gated channel modifier subfamily S member 2
chr5_-_132011794 0.02 ENST00000650697.1
acyl-CoA synthetase long chain family member 6
chr11_+_102317542 0.02 ENST00000532808.5
baculoviral IAP repeat containing 3
chr10_-_73168052 0.02 ENST00000430082.6
ENST00000454759.6
ENST00000413026.1
ENST00000453402.5
ecdysoneless cell cycle regulator
chr2_-_85561481 0.02 ENST00000233838.9
gamma-glutamyl carboxylase
chr10_-_49970203 0.02 ENST00000402038.7
poly(ADP-ribose) glycohydrolase
chr8_+_141416141 0.02 ENST00000680615.1
protein tyrosine phosphatase 4A3
chr20_-_2664186 0.02 ENST00000474315.5
ENST00000380843.9
ENST00000380851.9
ENST00000613370.1
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
chr1_+_11934651 0.02 ENST00000449038.5
ENST00000196061.5
ENST00000429000.6
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
chr3_-_167734510 0.02 ENST00000475915.6
ENST00000462725.6
ENST00000461494.5
programmed cell death 10
chr14_+_49893055 0.02 ENST00000298316.7
ADP ribosylation factor 6
chr11_+_65122301 0.02 ENST00000534078.1
ENST00000526171.5
ENST00000279242.7
ENST00000531705.1
ENST00000533943.1
mitochondrial ribosomal protein L49
chr8_+_141416078 0.02 ENST00000349124.3
protein tyrosine phosphatase 4A3
chr9_+_81988772 0.02 ENST00000344803.3
SPATA31 subfamily D member 1
chr12_+_53461015 0.02 ENST00000553064.6
ENST00000547859.2
poly(rC) binding protein 2
chr10_-_73167961 0.02 ENST00000372979.9
ecdysoneless cell cycle regulator
chr2_-_202871747 0.02 ENST00000358299.7
islet cell autoantigen 1 like
chr5_-_132011811 0.01 ENST00000379255.5
ENST00000430403.5
ENST00000357096.5
acyl-CoA synthetase long chain family member 6
chr8_-_120445140 0.01 ENST00000306185.8
mitochondrial ribosomal protein L13
chr17_+_32444379 0.01 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
proteasome 26S subunit, non-ATPase 11
chr9_+_136952256 0.01 ENST00000371633.8
lipocalin 12
chr5_-_175968280 0.01 ENST00000513482.1
ENST00000265097.9
ENST00000628318.2
THO complex 3
chr19_-_5903703 0.01 ENST00000586349.5
ENST00000585661.1
ENST00000592634.5
ENST00000418389.6
ENST00000308961.5
novel protein
NADH:ubiquinone oxidoreductase subunit A11
chr17_+_82458174 0.01 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr19_-_45973986 0.01 ENST00000676183.1
NOVA alternative splicing regulator 2
chr17_+_75610690 0.01 ENST00000642007.1
myosin XVB
chr19_-_50968775 0.01 ENST00000391808.5
kallikrein related peptidase 6
chr10_+_102918276 0.01 ENST00000369878.9
ENST00000369875.3
cyclin and CBS domain divalent metal cation transport mediator 2
chr17_+_82458649 0.01 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
nuclear prelamin A recognition factor
chr11_+_126405582 0.01 ENST00000526727.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr5_-_179617581 0.01 ENST00000523449.5
heterogeneous nuclear ribonucleoprotein H1
chr16_+_31214088 0.01 ENST00000613872.1
tripartite motif containing 72
chr9_+_136952896 0.01 ENST00000371632.7
lipocalin 12
chr1_+_144592868 0.00 ENST00000581138.3
peptidylprolyl isomerase A like 4F
chr2_-_202871611 0.00 ENST00000392237.6
ENST00000416760.5
ENST00000412210.5
islet cell autoantigen 1 like
chr1_-_144373659 0.00 ENST00000581164.1
peptidylprolyl isomerase A like 4E
chr5_+_3595820 0.00 ENST00000302006.4
iroquois homeobox 1
chr1_+_26317950 0.00 ENST00000374213.3
CD52 molecule
chr1_+_154993581 0.00 ENST00000392487.1
lens epithelial protein
chr17_-_63931354 0.00 ENST00000647774.1
novel protein
chr11_+_60455839 0.00 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr17_-_82840010 0.00 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.2 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.1 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.9 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0098592 microspike(GO:0044393) cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0030478 actin cap(GO:0030478)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle