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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for ZNF8

Z-value: 0.19

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Transcription factors associated with ZNF8

Gene Symbol Gene ID Gene Info
ENSG00000278129.2 ZNF8
ENSG00000278129.2 ZNF8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF8hg38_v1_chr19_+_58278948_582789920.077.4e-01Click!

Activity profile of ZNF8 motif

Sorted Z-values of ZNF8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_13668702 0.28 ENST00000532701.1
fatty acyl-CoA reductase 1
chr3_-_9952337 0.14 ENST00000411976.2
ENST00000412055.6
proline rich transmembrane protein 3
chr1_-_186375671 0.10 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr3_+_113838772 0.09 ENST00000358160.9
GRAM domain containing 1C
chr6_+_29723340 0.09 ENST00000334668.8
major histocompatibility complex, class I, F
chr19_+_37507129 0.09 ENST00000586138.5
ENST00000588578.5
ENST00000587986.5
zinc finger protein 793
chr6_-_18155053 0.08 ENST00000309983.5
thiopurine S-methyltransferase
chr4_-_185425941 0.08 ENST00000264689.11
ENST00000505357.1
UFM1 specific peptidase 2
chr17_+_77185210 0.08 ENST00000431431.6
SEC14 like lipid binding 1
chr6_+_29723421 0.08 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr6_-_81752671 0.08 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr2_-_171433950 0.07 ENST00000375258.9
ENST00000442541.1
ENST00000392599.6
methyltransferase like 8
chr2_+_171434196 0.07 ENST00000375255.8
ENST00000539783.5
DDB1 and CUL4 associated factor 17
chr6_-_107459504 0.06 ENST00000369037.9
ENST00000369031.4
decaprenyl diphosphate synthase subunit 2
chr12_-_122266425 0.06 ENST00000643696.1
ENST00000267199.9
VPS33A core subunit of CORVET and HOPS complexes
chr1_-_100249815 0.06 ENST00000370131.3
ENST00000681617.1
ENST00000681780.1
ENST00000370132.8
dihydrolipoamide branched chain transacylase E2
chr6_+_18155399 0.05 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
lysine demethylase 1B
chr16_-_53503192 0.05 ENST00000568596.5
ENST00000394657.12
ENST00000570004.5
ENST00000564497.1
ENST00000300245.8
AKT interacting protein
chr13_-_21176540 0.05 ENST00000400018.7
ENST00000314759.6
spindle and kinetochore associated complex subunit 3
chr9_-_37576365 0.05 ENST00000432825.7
F-box protein 10
chr17_+_35809474 0.05 ENST00000604879.5
ENST00000603427.5
ENST00000603777.5
ENST00000605844.6
ENST00000604841.5
TATA-box binding protein associated factor 15
chr11_-_46617170 0.05 ENST00000326737.3
harbinger transposase derived 1
chr12_-_46268989 0.04 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
solute carrier family 38 member 1
chr1_+_70205708 0.04 ENST00000370950.7
serine and arginine rich splicing factor 11
chr4_-_76148382 0.04 ENST00000264883.8
ENST00000514987.5
ENST00000514901.5
nucleoporin 54
chr13_-_25287457 0.04 ENST00000381801.6
myotubularin related protein 6
chr11_+_13668653 0.04 ENST00000354817.8
fatty acyl-CoA reductase 1
chr13_+_52652828 0.04 ENST00000310528.9
ENST00000343788.10
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr5_+_103120264 0.03 ENST00000358359.8
diphosphoinositol pentakisphosphate kinase 2
chr19_-_55140922 0.03 ENST00000589745.5
troponin T1, slow skeletal type
chr16_+_29962049 0.03 ENST00000279396.11
ENST00000575829.6
ENST00000561899.6
transmembrane protein 219
chr2_+_119431846 0.03 ENST00000306406.5
transmembrane protein 37
chr10_+_988425 0.03 ENST00000360803.9
GTP binding protein 4
chr1_+_186375813 0.03 ENST00000419367.8
ENST00000287859.11
ENST00000367470.8
odr-4 GPCR localization factor homolog
chr3_-_46717855 0.03 ENST00000315170.13
serine protease 50
chr19_+_35248879 0.03 ENST00000347609.8
lipolysis stimulated lipoprotein receptor
chr4_+_169620509 0.03 ENST00000347613.8
chloride voltage-gated channel 3
chr19_+_35248994 0.03 ENST00000427250.5
ENST00000605618.6
lipolysis stimulated lipoprotein receptor
chr17_+_50508384 0.03 ENST00000436259.6
ENST00000652471.1
ENST00000323776.11
ENST00000419930.2
MYCBP associated protein
chr2_-_105329685 0.03 ENST00000393359.7
transforming growth factor beta receptor associated protein 1
chr8_+_26291758 0.03 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr4_+_185426234 0.03 ENST00000511138.5
ENST00000511581.5
ENST00000378850.5
chromosome 4 open reading frame 47
chr1_-_54801290 0.03 ENST00000371276.9
tetratricopeptide repeat domain 22
chr16_+_21953341 0.02 ENST00000268379.9
ENST00000561553.5
ENST00000565331.5
ubiquinol-cytochrome c reductase core protein 2
chr17_-_58514617 0.02 ENST00000682306.1
myotubularin related protein 4
chr2_+_197500371 0.02 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr2_+_32357009 0.02 ENST00000421745.6
baculoviral IAP repeat containing 6
chr13_+_21176629 0.02 ENST00000309594.5
mitochondrial ribosomal protein L57
chr4_-_52038260 0.02 ENST00000381431.10
sarcoglycan beta
chr13_+_36819214 0.02 ENST00000255476.3
regulatory factor X associated protein
chrX_+_130401962 0.01 ENST00000305536.11
ENST00000370947.1
RNA binding motif protein X-linked 2
chr2_+_197500398 0.01 ENST00000604458.1
HSPE1-MOB4 readthrough
chr22_-_38656353 0.01 ENST00000535113.7
family with sequence similarity 227 member A
chr1_-_70205531 0.01 ENST00000370952.4
leucine rich repeat containing 40
chr6_-_116279837 0.01 ENST00000368608.4
TSPY like 1
chr12_-_122266410 0.01 ENST00000451053.3
VPS33A core subunit of CORVET and HOPS complexes
chrX_-_93673558 0.01 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chr4_+_169620527 0.01 ENST00000360642.7
ENST00000512813.5
ENST00000513761.6
chloride voltage-gated channel 3
chr8_-_108248700 0.01 ENST00000220849.10
ENST00000678937.1
ENST00000678901.1
ENST00000678243.1
ENST00000677674.1
ENST00000521297.2
ENST00000677272.1
ENST00000522352.6
ENST00000678042.1
ENST00000519627.2
ENST00000521440.6
ENST00000678773.1
ENST00000676698.1
ENST00000518345.2
ENST00000677447.1
ENST00000676548.1
ENST00000519030.6
ENST00000518442.5
eukaryotic translation initiation factor 3 subunit E
chr6_+_44246166 0.00 ENST00000620073.4
heat shock protein 90 alpha family class B member 1
chr1_+_25338294 0.00 ENST00000374358.5
transmembrane protein 50A
chr9_+_1050330 0.00 ENST00000382255.7
ENST00000382251.7
ENST00000412350.6
ENST00000358146.7
doublesex and mab-3 related transcription factor 2
chr7_+_100706061 0.00 ENST00000303151.5
POP7 homolog, ribonuclease P/MRP subunit

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0031453 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway