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Illumina Body Map 2 (GSE30611)
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Results for AAGGCAC
Z-value: 1.95
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miRNA associated with seed AAGGCAC
| Name | miRBASE accession |
|---|---|
|
hsa-miR-124-3p.1
|
MIMAT0000422 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AAGGCAC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 12.5 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.1 | 7.9 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.4 | 6.1 | GO:0060056 | mammary gland involution(GO:0060056) |
| 1.2 | 6.0 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.1 | 5.4 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 5.1 | GO:1901998 | toxin transport(GO:1901998) |
| 0.7 | 5.0 | GO:1903923 | protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923) |
| 0.4 | 5.0 | GO:0000050 | urea cycle(GO:0000050) |
| 0.1 | 4.9 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 4.9 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.2 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 11.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 11.4 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 9.8 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 9.0 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 8.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 8.0 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 7.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 7.7 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 7.4 | GO:0031526 | brush border membrane(GO:0031526) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.0 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 11.8 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 10.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 9.8 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.4 | 9.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 7.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 7.3 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 7.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.2 | 6.0 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 5.5 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.2 | 11.0 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 10.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 9.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.2 | 9.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 8.8 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 8.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 8.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 7.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.2 | 6.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 7.3 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.3 | 6.8 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.4 | 6.6 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 5.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 5.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 5.1 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 5.0 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.3 | 4.9 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 4.9 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |