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Illumina Body Map 2 (GSE30611)

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Results for ALX1_ARX

Z-value: 0.62

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Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ALX1
ENSG00000180318.4 ALX homeobox 1
ARX
ENSG00000004848.8 aristaless related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARXhg38_v1_chrX_-_25015924_25016002-0.241.8e-01Click!
ALX1hg38_v1_chr12_+_85280199_85280237-0.029.2e-01Click!

Activity profile of ALX1_ARX motif

Sorted Z-values of ALX1_ARX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_195583931 4.85 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
APOD
apolipoprotein D
chr14_-_94770102 3.39 ENST00000238558.5
GSC
goosecoid homeobox
chr2_-_218010202 3.30 ENST00000646520.1
TNS1
tensin 1
chr10_-_29634964 3.17 ENST00000375398.6
ENST00000355867.8
SVIL
supervillin
chr1_-_151175966 2.71 ENST00000441701.1
ENST00000295314.9
TMOD4
tropomodulin 4
chr6_+_121437378 2.38 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr1_-_91906280 2.28 ENST00000370399.6
TGFBR3
transforming growth factor beta receptor 3
chr1_+_170663134 2.23 ENST00000367760.7
PRRX1
paired related homeobox 1
chr1_-_178869272 2.21 ENST00000444255.1
ANGPTL1
angiopoietin like 1
chr1_-_178871022 2.00 ENST00000367629.1
ANGPTL1
angiopoietin like 1
chr1_-_178871060 1.91 ENST00000234816.7
ANGPTL1
angiopoietin like 1
chr12_-_91153149 1.72 ENST00000550758.1
DCN
decorin
chr1_-_93681829 1.58 ENST00000260502.11
BCAR3
BCAR3 adaptor protein, NSP family member
chr10_+_68106109 1.49 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr3_-_158106408 1.44 ENST00000483851.7
SHOX2
short stature homeobox 2
chr2_+_176129680 1.40 ENST00000429017.2
ENST00000313173.6
HOXD8
homeobox D8
chr6_-_65707214 1.36 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
EYS
eyes shut homolog
chr14_+_22163226 1.35 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5
chr10_-_49188380 1.16 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
TMEM273
transmembrane protein 273
chr6_-_75363003 1.15 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr8_-_6563409 1.12 ENST00000325203.9
ANGPT2
angiopoietin 2
chr12_+_12725897 1.06 ENST00000326765.10
APOLD1
apolipoprotein L domain containing 1
chr3_+_138621207 1.02 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr12_-_21775581 0.99 ENST00000537950.1
ENST00000665145.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chrX_-_11265975 0.95 ENST00000303025.10
ENST00000657361.1
ARHGAP6
Rho GTPase activating protein 6
chr6_+_34236865 0.94 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
HMGA1
high mobility group AT-hook 1
chr7_-_111392915 0.90 ENST00000450877.5
IMMP2L
inner mitochondrial membrane peptidase subunit 2
chr2_+_36696790 0.88 ENST00000497382.5
ENST00000404084.5
ENST00000379241.7
ENST00000401530.5
VIT
vitrin
chr2_+_36696686 0.86 ENST00000379242.7
ENST00000389975.7
VIT
vitrin
chr6_-_169250825 0.86 ENST00000676869.1
ENST00000676760.1
THBS2
thrombospondin 2
chr11_-_96343170 0.84 ENST00000524717.6
MAML2
mastermind like transcriptional coactivator 2
chr3_+_138621225 0.84 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr12_+_54016879 0.83 ENST00000303406.4
HOXC4
homeobox C4
chr1_+_186828941 0.83 ENST00000367466.4
PLA2G4A
phospholipase A2 group IVA
chr19_+_49513353 0.82 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr12_-_15662692 0.82 ENST00000540613.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr5_+_40909490 0.80 ENST00000313164.10
C7
complement C7
chr12_+_14419136 0.79 ENST00000545769.1
ENST00000428217.6
ENST00000396279.2
ENST00000542514.5
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr21_+_46635595 0.79 ENST00000451211.6
ENST00000458387.6
ENST00000397638.6
ENST00000291705.11
ENST00000397637.5
ENST00000334494.8
ENST00000397628.5
ENST00000355680.8
ENST00000440086.5
PRMT2
protein arginine methyltransferase 2
chr6_-_32941018 0.77 ENST00000418107.3
HLA-DMB
major histocompatibility complex, class II, DM beta
chr14_-_21098848 0.77 ENST00000556174.5
ENST00000554478.5
ENST00000553980.1
ENST00000421093.6
ZNF219
zinc finger protein 219
chr3_+_12287859 0.74 ENST00000309576.11
ENST00000397015.7
PPARG
peroxisome proliferator activated receptor gamma
chr18_-_24311495 0.73 ENST00000357041.8
OSBPL1A
oxysterol binding protein like 1A
chr1_+_207325629 0.73 ENST00000618707.2
CD55
CD55 molecule (Cromer blood group)
chr9_-_92536067 0.72 ENST00000444490.6
ECM2
extracellular matrix protein 2
chr3_+_12287899 0.72 ENST00000643888.2
PPARG
peroxisome proliferator activated receptor gamma
chr5_+_137867868 0.71 ENST00000515645.1
MYOT
myotilin
chr3_-_125055987 0.70 ENST00000311127.9
HEG1
heart development protein with EGF like domains 1
chr5_-_135399863 0.68 ENST00000510038.1
ENST00000304332.8
MACROH2A1
macroH2A.1 histone
chr9_-_92536031 0.66 ENST00000344604.9
ENST00000375540.5
ECM2
extracellular matrix protein 2
chr3_+_69936583 0.66 ENST00000314557.10
ENST00000394351.9
MITF
melanocyte inducing transcription factor
chr2_+_36696758 0.65 ENST00000457137.6
VIT
vitrin
chr12_-_118359639 0.65 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr8_-_61689768 0.61 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
ASPH
aspartate beta-hydroxylase
chr16_+_68085420 0.60 ENST00000349223.9
NFATC3
nuclear factor of activated T cells 3
chr17_+_46511511 0.59 ENST00000576629.5
LRRC37A2
leucine rich repeat containing 37 member A2
chr16_+_68085552 0.58 ENST00000329524.8
NFATC3
nuclear factor of activated T cells 3
chr9_-_92536645 0.58 ENST00000395534.2
ECM2
extracellular matrix protein 2
chr18_-_55322334 0.57 ENST00000630720.3
TCF4
transcription factor 4
chr3_+_151873634 0.56 ENST00000362032.6
SUCNR1
succinate receptor 1
chr3_-_27722316 0.55 ENST00000449599.4
EOMES
eomesodermin
chr3_-_3109980 0.55 ENST00000256452.7
ENST00000311981.12
ENST00000430514.6
ENST00000456302.5
IL5RA
interleukin 5 receptor subunit alpha
chr8_-_121641424 0.54 ENST00000303924.5
HAS2
hyaluronan synthase 2
chr16_+_68085344 0.54 ENST00000575270.5
ENST00000346183.8
NFATC3
nuclear factor of activated T cells 3
chr1_-_79188467 0.53 ENST00000656300.1
ADGRL4
adhesion G protein-coupled receptor L4
chr2_+_118942188 0.53 ENST00000327097.5
MARCO
macrophage receptor with collagenous structure
chr21_-_41926680 0.53 ENST00000329623.11
C2CD2
C2 calcium dependent domain containing 2
chr6_-_110358313 0.53 ENST00000338882.5
METTL24
methyltransferase like 24
chr2_+_54456311 0.52 ENST00000615901.4
ENST00000356805.9
SPTBN1
spectrin beta, non-erythrocytic 1
chr10_-_49188312 0.52 ENST00000453436.5
ENST00000474718.5
TMEM273
transmembrane protein 273
chr18_-_55321986 0.51 ENST00000570287.6
TCF4
transcription factor 4
chr6_+_54099565 0.51 ENST00000511678.5
MLIP
muscular LMNA interacting protein
chr4_+_94455245 0.50 ENST00000508216.5
ENST00000514743.5
PDLIM5
PDZ and LIM domain 5
chr4_-_67963441 0.50 ENST00000508048.6
TMPRSS11A
transmembrane serine protease 11A
chr11_-_16397521 0.49 ENST00000533411.5
SOX6
SRY-box transcription factor 6
chr2_-_88861920 0.49 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chrX_-_15314543 0.49 ENST00000344384.8
ASB11
ankyrin repeat and SOCS box containing 11
chr19_-_43465596 0.46 ENST00000244333.4
LYPD3
LY6/PLAUR domain containing 3
chr16_-_21431553 0.46 ENST00000534903.1
NPIPB3
nuclear pore complex interacting protein family member B3
chr12_-_89352395 0.46 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr1_+_159008978 0.46 ENST00000447473.6
IFI16
interferon gamma inducible protein 16
chr15_+_100877714 0.45 ENST00000561338.5
ALDH1A3
aldehyde dehydrogenase 1 family member A3
chr22_-_28306645 0.44 ENST00000612946.4
TTC28
tetratricopeptide repeat domain 28
chr3_+_69936629 0.44 ENST00000394348.2
ENST00000531774.1
MITF
melanocyte inducing transcription factor
chr4_+_68447453 0.43 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr18_-_55322215 0.42 ENST00000457482.7
TCF4
transcription factor 4
chrX_-_15600953 0.42 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
ACE2
angiotensin I converting enzyme 2
chr7_-_93148345 0.41 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
SAMD9L
sterile alpha motif domain containing 9 like
chr3_-_196515315 0.40 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chrX_-_19799751 0.39 ENST00000379698.8
SH3KBP1
SH3 domain containing kinase binding protein 1
chr12_-_89352487 0.38 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr15_+_41774459 0.38 ENST00000457542.7
ENST00000456763.6
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr1_-_79188390 0.37 ENST00000662530.1
ADGRL4
adhesion G protein-coupled receptor L4
chr8_+_85987287 0.36 ENST00000521564.1
ATP6V0D2
ATPase H+ transporting V0 subunit d2
chr2_+_161136901 0.35 ENST00000259075.6
ENST00000432002.5
TANK
TRAF family member associated NFKB activator
chrX_+_108044967 0.35 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr6_+_54099538 0.34 ENST00000447836.6
MLIP
muscular LMNA interacting protein
chr5_+_141364153 0.32 ENST00000518069.2
PCDHGA5
protocadherin gamma subfamily A, 5
chr1_+_24556087 0.31 ENST00000374392.3
NCMAP
non-compact myelin associated protein
chr12_+_57610150 0.31 ENST00000333972.11
ARHGEF25
Rho guanine nucleotide exchange factor 25
chr6_-_132659178 0.30 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr16_-_21864103 0.29 ENST00000541674.5
NPIPB4
nuclear pore complex interacting protein family member B4
chr8_-_85341659 0.29 ENST00000522389.5
CA1
carbonic anhydrase 1
chr2_+_28778848 0.29 ENST00000418910.1
PPP1CB
protein phosphatase 1 catalytic subunit beta
chrX_-_55182442 0.29 ENST00000545075.3
MTRNR2L10
MT-RNR2 like 10
chr22_-_30246739 0.28 ENST00000403987.3
ENST00000249075.4
LIF
LIF interleukin 6 family cytokine
chr10_-_101229449 0.28 ENST00000370193.4
LBX1
ladybird homeobox 1
chr2_+_118942290 0.28 ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr11_-_13496018 0.27 ENST00000529816.1
PTH
parathyroid hormone
chr1_-_110391041 0.27 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
SLC16A4
solute carrier family 16 member 4
chr7_-_7535863 0.27 ENST00000399429.8
COL28A1
collagen type XXVIII alpha 1 chain
chr6_+_3258914 0.27 ENST00000438998.7
ENST00000419065.6
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome assembly chaperone 4
chr11_+_66011994 0.26 ENST00000312134.3
CST6
cystatin E/M
chr12_-_68225806 0.26 ENST00000229134.5
IL26
interleukin 26
chr7_-_55552741 0.26 ENST00000418904.5
VOPP1
VOPP1 WW domain binding protein
chr16_-_3372666 0.26 ENST00000399974.5
MTRNR2L4
MT-RNR2 like 4
chr11_-_102705737 0.25 ENST00000260229.5
MMP27
matrix metallopeptidase 27
chr8_+_38820332 0.25 ENST00000518809.5
ENST00000520611.1
TACC1
transforming acidic coiled-coil containing protein 1
chr12_-_118359105 0.25 ENST00000541186.5
ENST00000539872.5
TAOK3
TAO kinase 3
chr16_+_53435612 0.25 ENST00000544405.6
RBL2
RB transcriptional corepressor like 2
chr5_+_146447304 0.24 ENST00000296702.9
ENST00000394421.7
ENST00000679501.2
TCERG1
transcription elongation regulator 1
chr14_+_23240346 0.24 ENST00000430154.6
RNF212B
ring finger protein 212B
chr7_+_107583919 0.24 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr6_+_112236806 0.24 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4-AS1
ENSG00000281613.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chr8_-_85341705 0.23 ENST00000517618.5
CA1
carbonic anhydrase 1
chr16_+_24537693 0.23 ENST00000564314.5
ENST00000567686.5
RBBP6
RB binding protein 6, ubiquitin ligase
chr15_-_43800132 0.23 ENST00000299969.10
ENST00000319327.7
SERINC4
serine incorporator 4
chrX_+_1591590 0.23 ENST00000313871.9
ENST00000381261.8
AKAP17A
A-kinase anchoring protein 17A
chr6_+_30914329 0.23 ENST00000541562.6
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr6_+_30914205 0.23 ENST00000672801.1
ENST00000321897.9
ENST00000625423.2
ENST00000676266.1
ENST00000428017.5
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr1_+_186296267 0.22 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
PRG4
proteoglycan 4
chr3_+_130850585 0.22 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr4_-_89029881 0.21 ENST00000506913.1
FAM13A
family with sequence similarity 13 member A
chr19_-_6393131 0.21 ENST00000394456.10
GTF2F1
general transcription factor IIF subunit 1
chr7_+_20615653 0.21 ENST00000404938.7
ABCB5
ATP binding cassette subfamily B member 5
chr9_-_135639540 0.21 ENST00000371763.6
ENST00000613244.1
GLT6D1
glycosyltransferase 6 domain containing 1
chr1_-_21050952 0.21 ENST00000264211.12
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
chrX_+_108045050 0.21 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr3_+_140941792 0.21 ENST00000446041.6
ENST00000324194.12
ENST00000507429.5
SLC25A36
solute carrier family 25 member 36
chr5_-_60488055 0.21 ENST00000505507.6
ENST00000515835.2
ENST00000502484.6
PDE4D
phosphodiesterase 4D
chr4_-_82848843 0.20 ENST00000511338.1
SEC31A
SEC31 homolog A, COPII coat complex component
chr11_-_58268260 0.20 ENST00000395079.2
OR10W1
olfactory receptor family 10 subfamily W member 1
chr13_+_53028806 0.19 ENST00000219022.3
OLFM4
olfactomedin 4
chr9_+_121567057 0.19 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr10_-_110304894 0.19 ENST00000369603.10
SMNDC1
survival motor neuron domain containing 1
chr6_+_3258888 0.19 ENST00000380305.4
PSMG4
proteasome assembly chaperone 4
chr6_-_154430495 0.19 ENST00000424998.3
CNKSR3
CNKSR family member 3
chr19_-_6393205 0.18 ENST00000595047.5
GTF2F1
general transcription factor IIF subunit 1
chr2_-_144520315 0.18 ENST00000465070.5
ENST00000465308.5
ENST00000636471.1
ENST00000629520.2
ENST00000675069.1
ENST00000636026.2
ENST00000444559.5
ZEB2
zinc finger E-box binding homeobox 2
chr6_-_111483700 0.18 ENST00000435970.5
ENST00000358835.7
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chrX_-_32412220 0.18 ENST00000619831.5
DMD
dystrophin
chr18_+_68798065 0.18 ENST00000360242.9
CCDC102B
coiled-coil domain containing 102B
chr12_+_59689337 0.17 ENST00000261187.8
SLC16A7
solute carrier family 16 member 7
chr3_-_27722699 0.16 ENST00000461503.2
EOMES
eomesodermin
chr15_+_63529142 0.16 ENST00000268049.11
USP3
ubiquitin specific peptidase 3
chrX_+_16650155 0.16 ENST00000380200.3
S100G
S100 calcium binding protein G
chr17_-_41118369 0.16 ENST00000391413.4
KRTAP4-11
keratin associated protein 4-11
chr11_-_111876567 0.16 ENST00000526587.2
ENSG00000258529.5
novel protein
chr4_+_75724569 0.16 ENST00000514213.7
ENST00000264904.8
USO1
USO1 vesicle transport factor
chr15_-_52678560 0.16 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
FAM214A
family with sequence similarity 214 member A
chr15_-_43106022 0.15 ENST00000627960.1
ENST00000290650.9
UBR1
ubiquitin protein ligase E3 component n-recognin 1
chr12_-_52553139 0.15 ENST00000267119.6
KRT71
keratin 71
chr12_-_118190510 0.15 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr6_+_27824084 0.15 ENST00000355057.3
H4C11
H4 clustered histone 11
chr7_+_142384328 0.15 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr17_-_62808339 0.15 ENST00000583600.5
MARCHF10
membrane associated ring-CH-type finger 10
chr15_+_57219411 0.14 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
TCF12
transcription factor 12
chr4_-_142305935 0.14 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr17_-_62808299 0.14 ENST00000311269.10
MARCHF10
membrane associated ring-CH-type finger 10
chr12_-_57479552 0.13 ENST00000424809.6
ARHGAP9
Rho GTPase activating protein 9
chr5_+_141364231 0.13 ENST00000611914.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr17_+_44957907 0.13 ENST00000678938.1
NMT1
N-myristoyltransferase 1
chr5_+_141338753 0.13 ENST00000528330.2
ENST00000394576.3
PCDHGA2
protocadherin gamma subfamily A, 2
chr5_+_69565122 0.13 ENST00000507595.1
GTF2H2C
GTF2H2 family member C
chr4_+_185204237 0.12 ENST00000618785.4
ENST00000504273.5
SNX25
sorting nexin 25
chr14_+_21098819 0.12 ENST00000418511.6
ENST00000554329.6
TMEM253
transmembrane protein 253
chr21_-_30598902 0.12 ENST00000334897.4
KRTAP6-2
keratin associated protein 6-2
chrX_-_41665766 0.12 ENST00000643043.2
ENST00000486402.1
ENST00000646087.2
CASK
calcium/calmodulin dependent serine protein kinase
chr17_-_40799939 0.12 ENST00000306658.8
KRT28
keratin 28
chr20_+_31547367 0.11 ENST00000394552.3
MCTS2P
MCTS family member 2, pseudogene
chr17_-_62808283 0.11 ENST00000544856.6
MARCHF10
membrane associated ring-CH-type finger 10
chr6_-_26199272 0.11 ENST00000650491.1
ENST00000635200.1
ENST00000341023.2
ENSG00000282988.2
H2AC7
novel protein
H2A clustered histone 7
chr3_-_151278359 0.11 ENST00000494668.1
P2RY14
purinergic receptor P2Y14
chr8_-_16567362 0.11 ENST00000518026.5
MSR1
macrophage scavenger receptor 1
chr3_-_47892743 0.11 ENST00000420772.6
MAP4
microtubule associated protein 4
chr12_+_53461015 0.11 ENST00000553064.6
ENST00000547859.2
PCBP2
poly(rC) binding protein 2
chrX_+_38352573 0.11 ENST00000039007.5
OTC
ornithine transcarbamylase
chr4_-_185657520 0.11 ENST00000438278.5
SORBS2
sorbin and SH3 domain containing 2
chr17_+_73232400 0.11 ENST00000535032.7
ENST00000577615.5
ENST00000585109.5
C17orf80
chromosome 17 open reading frame 80
chr2_+_43774033 0.11 ENST00000260605.12
ENST00000406852.7
ENST00000398823.6
ENST00000605786.5
DYNC2LI1
dynein cytoplasmic 2 light intermediate chain 1
chr4_-_142305826 0.10 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr9_+_72577369 0.10 ENST00000651183.1
TMC1
transmembrane channel like 1
chr3_-_165078480 0.10 ENST00000264382.8
SI
sucrase-isomaltase
chrX_-_77634229 0.10 ENST00000675732.1
ATRX
ATRX chromatin remodeler
chr4_+_94207596 0.10 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_-_110499546 0.10 ENST00000552130.6
VPS29
VPS29 retromer complex component
chr14_+_67364849 0.10 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2 subunit alpha
chr3_-_12545499 0.10 ENST00000564146.4
MKRN2OS
MKRN2 opposite strand
chr7_-_116159886 0.09 ENST00000484212.5
TFEC
transcription factor EC
chr17_-_73232218 0.09 ENST00000583024.1
ENST00000403627.7
ENST00000405159.7
ENST00000581110.1
FAM104A
family with sequence similarity 104 member A

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.1 3.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.6 2.4 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.5 2.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.4 1.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.3 0.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 0.8 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.3 2.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 0.8 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 1.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 0.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 2.5 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.5 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.7 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 1.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.5 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 1.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.8 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.2 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 1.7 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 1.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.4 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 3.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 1.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 3.3 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 1.0 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.9 GO:2000142 regulation of DNA-templated transcription, initiation(GO:2000142)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 2.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 0.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 3.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 4.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 2.4 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 2.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0044207 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 4.4 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 6.3 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.4 2.0 GO:0070052 collagen V binding(GO:0070052)
0.3 2.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 0.8 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 0.8 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 1.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.5 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 3.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 3.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 4.8 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.5 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 1.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.8 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 5.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 4.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 6.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation