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Illumina Body Map 2 (GSE30611)
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Results for ALX3
Z-value: 1.27
Motif logo
Transcription factors associated with ALX3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ALX3
|
ENSG00000156150.9 | ALX homeobox 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ALX3 | hg38_v1_chr1_-_110064916_110064927 | -0.16 | 3.8e-01 | Click! |
Activity profile of ALX3 motif
Sorted Z-values of ALX3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_88861563 | 5.81 |
ENST00000624935.3
ENST00000390241.3 |
ENSG00000240040.6
IGKJ2
|
novel transcript immunoglobulin kappa joining 2 |
| chr16_+_72054477 | 5.57 |
ENST00000355906.10
ENST00000570083.5 ENST00000228226.12 ENST00000398131.6 ENST00000569639.5 ENST00000564499.5 ENST00000357763.8 ENST00000613898.1 ENST00000562526.5 ENST00000565574.5 ENST00000568417.6 |
HP
|
haptoglobin |
| chr4_-_25863537 | 5.04 |
ENST00000502949.5
ENST00000264868.9 ENST00000513691.1 ENST00000514872.1 |
SEL1L3
|
SEL1L family member 3 |
| chr2_-_89177160 | 4.34 |
ENST00000484817.1
|
IGKV2-24
|
immunoglobulin kappa variable 2-24 |
| chr14_-_106038355 | 4.28 |
ENST00000390597.3
|
IGHV2-5
|
immunoglobulin heavy variable 2-5 |
| chr2_-_89085787 | 4.18 |
ENST00000390252.2
|
IGKV3-15
|
immunoglobulin kappa variable 3-15 |
| chr13_-_46168495 | 4.13 |
ENST00000416500.5
|
LCP1
|
lymphocyte cytosolic protein 1 |
| chr7_-_87713287 | 3.81 |
ENST00000416177.1
ENST00000265724.8 ENST00000543898.5 |
ABCB1
|
ATP binding cassette subfamily B member 1 |
| chr16_+_72063226 | 3.62 |
ENST00000540303.7
ENST00000356967.6 ENST00000561690.1 |
HPR
|
haptoglobin-related protein |
| chr2_+_90172802 | 3.58 |
ENST00000390277.3
|
IGKV3D-11
|
immunoglobulin kappa variable 3D-11 |
| chr18_+_31591869 | 3.51 |
ENST00000237014.8
|
TTR
|
transthyretin |
| chr20_+_59019397 | 3.45 |
ENST00000217133.2
|
TUBB1
|
tubulin beta 1 class VI |
| chr2_+_90234809 | 3.41 |
ENST00000443397.5
|
IGKV3D-7
|
immunoglobulin kappa variable 3D-7 |
| chr12_-_10130143 | 3.35 |
ENST00000298523.9
ENST00000396484.6 ENST00000310002.4 ENST00000304084.13 |
CLEC7A
|
C-type lectin domain containing 7A |
| chr19_+_17527250 | 3.18 |
ENST00000599164.6
ENST00000449408.6 ENST00000600871.5 ENST00000599124.1 |
NIBAN3
|
niban apoptosis regulator 3 |
| chr16_+_11965193 | 3.01 |
ENST00000053243.6
ENST00000396495.3 |
TNFRSF17
|
TNF receptor superfamily member 17 |
| chr2_+_90038848 | 3.00 |
ENST00000390270.2
|
IGKV3D-20
|
immunoglobulin kappa variable 3D-20 |
| chr1_-_92486916 | 2.88 |
ENST00000294702.6
|
GFI1
|
growth factor independent 1 transcriptional repressor |
| chr2_+_87338511 | 2.69 |
ENST00000421835.2
|
IGKV3OR2-268
|
immunoglobulin kappa variable 3/OR2-268 (non-functional) |
| chr14_-_106593319 | 2.68 |
ENST00000390627.3
|
IGHV3-53
|
immunoglobulin heavy variable 3-53 |
| chr13_+_77741160 | 2.67 |
ENST00000314070.9
ENST00000351546.7 |
SLAIN1
|
SLAIN motif family member 1 |
| chr12_-_10130241 | 2.65 |
ENST00000353231.9
ENST00000525605.1 |
CLEC7A
|
C-type lectin domain containing 7A |
| chr7_+_37683733 | 2.61 |
ENST00000334425.2
ENST00000450180.5 |
GPR141
|
G protein-coupled receptor 141 |
| chr1_-_113871665 | 2.59 |
ENST00000528414.5
ENST00000460620.5 ENST00000359785.10 ENST00000420377.6 ENST00000525799.1 ENST00000538253.5 |
PTPN22
|
protein tyrosine phosphatase non-receptor type 22 |
| chr14_-_106470788 | 2.43 |
ENST00000434710.1
|
IGHV3-43
|
immunoglobulin heavy variable 3-43 |
| chr14_+_21997531 | 2.38 |
ENST00000390445.2
|
TRAV17
|
T cell receptor alpha variable 17 |
| chr9_-_114348966 | 2.35 |
ENST00000374079.8
|
AKNA
|
AT-hook transcription factor |
| chr19_-_51417791 | 2.26 |
ENST00000353836.9
|
SIGLEC10
|
sialic acid binding Ig like lectin 10 |
| chr2_+_68734861 | 2.24 |
ENST00000467265.5
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr2_+_68734773 | 2.23 |
ENST00000409202.8
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr17_-_66229380 | 2.22 |
ENST00000205948.11
|
APOH
|
apolipoprotein H |
| chr3_+_186974957 | 2.17 |
ENST00000438590.5
|
ST6GAL1
|
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
| chr2_+_134838610 | 2.13 |
ENST00000356140.10
ENST00000392928.5 |
ACMSD
|
aminocarboxymuconate semialdehyde decarboxylase |
| chr2_+_90004792 | 2.12 |
ENST00000462693.1
|
IGKV2D-24
|
immunoglobulin kappa variable 2D-24 (non-functional) |
| chr7_+_142300924 | 2.12 |
ENST00000455382.2
|
TRBV2
|
T cell receptor beta variable 2 |
| chr21_-_14546297 | 2.08 |
ENST00000400566.6
ENST00000400564.5 |
SAMSN1
|
SAM domain, SH3 domain and nuclear localization signals 1 |
| chr16_-_28623560 | 2.05 |
ENST00000350842.8
|
SULT1A1
|
sulfotransferase family 1A member 1 |
| chr6_+_160121809 | 1.98 |
ENST00000366963.9
|
SLC22A1
|
solute carrier family 22 member 1 |
| chr14_+_21621801 | 1.98 |
ENST00000542354.1
|
TRAV1-1
|
T cell receptor alpha variable 1-1 |
| chr7_+_142450941 | 1.97 |
ENST00000390368.2
|
TRBV6-5
|
T cell receptor beta variable 6-5 |
| chr2_-_224947030 | 1.97 |
ENST00000409592.7
|
DOCK10
|
dedicator of cytokinesis 10 |
| chr12_+_8513499 | 1.96 |
ENST00000299665.3
|
CLEC4D
|
C-type lectin domain family 4 member D |
| chr19_-_51417700 | 1.94 |
ENST00000529627.1
ENST00000439889.6 |
SIGLEC10
|
sialic acid binding Ig like lectin 10 |
| chr3_+_122055355 | 1.91 |
ENST00000330540.7
ENST00000469710.5 ENST00000493101.5 |
CD86
|
CD86 molecule |
| chr14_-_106211453 | 1.89 |
ENST00000390606.3
|
IGHV3-20
|
immunoglobulin heavy variable 3-20 |
| chr4_-_36243939 | 1.86 |
ENST00000506189.1
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| chr6_+_160121859 | 1.83 |
ENST00000324965.8
ENST00000457470.6 |
SLC22A1
|
solute carrier family 22 member 1 |
| chr16_+_11965234 | 1.80 |
ENST00000562385.1
|
TNFRSF17
|
TNF receptor superfamily member 17 |
| chr2_-_101308681 | 1.78 |
ENST00000295317.4
|
RNF149
|
ring finger protein 149 |
| chr2_+_218129277 | 1.75 |
ENST00000428565.1
|
CXCR2
|
C-X-C motif chemokine receptor 2 |
| chr19_-_58353482 | 1.73 |
ENST00000263100.8
|
A1BG
|
alpha-1-B glycoprotein |
| chr13_+_77741212 | 1.73 |
ENST00000441784.5
|
SLAIN1
|
SLAIN motif family member 1 |
| chr9_+_92947516 | 1.71 |
ENST00000375482.8
|
FGD3
|
FYVE, RhoGEF and PH domain containing 3 |
| chr2_+_165239432 | 1.69 |
ENST00000636071.2
ENST00000636985.2 |
SCN2A
|
sodium voltage-gated channel alpha subunit 2 |
| chr4_-_163613505 | 1.67 |
ENST00000339875.9
|
MARCHF1
|
membrane associated ring-CH-type finger 1 |
| chr3_-_191282383 | 1.67 |
ENST00000427544.6
|
UTS2B
|
urotensin 2B |
| chr14_+_22202561 | 1.58 |
ENST00000390460.1
|
TRAV26-2
|
T cell receptor alpha variable 26-2 |
| chr2_+_165239388 | 1.57 |
ENST00000424833.5
ENST00000375437.7 ENST00000631182.3 |
SCN2A
|
sodium voltage-gated channel alpha subunit 2 |
| chr18_-_69956924 | 1.56 |
ENST00000581982.5
ENST00000280200.8 |
CD226
|
CD226 molecule |
| chr16_+_31259922 | 1.54 |
ENST00000648685.1
ENST00000544665.9 |
ITGAM
|
integrin subunit alpha M |
| chr2_-_88979016 | 1.48 |
ENST00000390247.2
|
IGKV3-7
|
immunoglobulin kappa variable 3-7 (non-functional) |
| chr19_+_17527232 | 1.47 |
ENST00000601861.5
|
NIBAN3
|
niban apoptosis regulator 3 |
| chr20_-_35147285 | 1.45 |
ENST00000374491.3
ENST00000374492.8 |
EDEM2
|
ER degradation enhancing alpha-mannosidase like protein 2 |
| chr15_+_58410543 | 1.42 |
ENST00000356113.10
ENST00000414170.7 |
LIPC
|
lipase C, hepatic type |
| chr1_-_150765785 | 1.41 |
ENST00000680311.1
ENST00000681728.1 ENST00000680288.1 |
CTSS
|
cathepsin S |
| chr7_+_37683847 | 1.36 |
ENST00000447769.1
|
GPR141
|
G protein-coupled receptor 141 |
| chr19_-_51804104 | 1.31 |
ENST00000594900.1
|
FPR1
|
formyl peptide receptor 1 |
| chr6_+_26402237 | 1.29 |
ENST00000476549.6
ENST00000450085.6 ENST00000425234.6 ENST00000427334.5 ENST00000506698.1 ENST00000289361.11 |
BTN3A1
|
butyrophilin subfamily 3 member A1 |
| chrX_+_108045050 | 1.28 |
ENST00000458383.1
ENST00000217957.10 |
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr4_+_70993542 | 1.28 |
ENST00000504730.5
ENST00000504952.1 ENST00000286648.10 |
DCK
|
deoxycytidine kinase |
| chr16_+_31873772 | 1.26 |
ENST00000394846.7
ENST00000300870.15 |
ZNF267
|
zinc finger protein 267 |
| chr4_-_48114523 | 1.26 |
ENST00000506073.1
|
TXK
|
TXK tyrosine kinase |
| chr16_-_28597042 | 1.25 |
ENST00000533150.5
ENST00000335715.9 |
SULT1A2
|
sulfotransferase family 1A member 2 |
| chr19_-_3557563 | 1.23 |
ENST00000389395.7
ENST00000355415.7 |
MFSD12
|
major facilitator superfamily domain containing 12 |
| chr16_-_28623330 | 1.21 |
ENST00000677940.1
|
ENSG00000288656.1
|
novel protein |
| chr1_-_111488795 | 1.20 |
ENST00000472933.2
|
TMIGD3
|
transmembrane and immunoglobulin domain containing 3 |
| chr7_+_8433602 | 1.20 |
ENST00000405863.6
|
NXPH1
|
neurexophilin 1 |
| chr11_+_35180279 | 1.16 |
ENST00000531873.5
|
CD44
|
CD44 molecule (Indian blood group) |
| chr6_-_49964160 | 1.15 |
ENST00000322066.4
|
DEFB114
|
defensin beta 114 |
| chr1_+_66354375 | 1.13 |
ENST00000480109.2
|
PDE4B
|
phosphodiesterase 4B |
| chr1_+_117001744 | 1.12 |
ENST00000256652.8
ENST00000682167.1 ENST00000369470.1 |
CD101
|
CD101 molecule |
| chr5_-_20575850 | 1.11 |
ENST00000507958.5
|
CDH18
|
cadherin 18 |
| chr2_+_209653171 | 1.11 |
ENST00000447185.5
|
MAP2
|
microtubule associated protein 2 |
| chr2_-_88861920 | 1.10 |
ENST00000390242.2
|
IGKJ1
|
immunoglobulin kappa joining 1 |
| chr10_-_97270638 | 1.07 |
ENST00000371027.5
|
ARHGAP19
|
Rho GTPase activating protein 19 |
| chr3_-_146528750 | 1.07 |
ENST00000483300.5
|
PLSCR1
|
phospholipid scramblase 1 |
| chr2_+_102337148 | 1.05 |
ENST00000311734.6
ENST00000409584.5 |
IL1RL1
|
interleukin 1 receptor like 1 |
| chr6_+_157981826 | 1.04 |
ENST00000355585.9
ENST00000640338.1 ENST00000367113.5 |
SYNJ2
|
synaptojanin 2 |
| chr12_+_56041893 | 1.04 |
ENST00000552361.1
ENST00000646449.2 |
RPS26
|
ribosomal protein S26 |
| chr19_-_54339146 | 1.04 |
ENST00000291759.5
|
LILRA4
|
leukocyte immunoglobulin like receptor A4 |
| chr12_-_10130082 | 1.02 |
ENST00000533022.5
|
CLEC7A
|
C-type lectin domain containing 7A |
| chrX_+_77910656 | 1.02 |
ENST00000343533.9
ENST00000341514.11 ENST00000645454.1 ENST00000642651.1 ENST00000644362.1 |
ATP7A
PGK1
|
ATPase copper transporting alpha phosphoglycerate kinase 1 |
| chr2_-_169031317 | 1.01 |
ENST00000650372.1
|
ABCB11
|
ATP binding cassette subfamily B member 11 |
| chr6_+_127577168 | 0.99 |
ENST00000329722.8
|
C6orf58
|
chromosome 6 open reading frame 58 |
| chr4_-_175812236 | 0.98 |
ENST00000505375.5
|
GPM6A
|
glycoprotein M6A |
| chr6_-_138512493 | 0.97 |
ENST00000533765.1
|
NHSL1
|
NHS like 1 |
| chr14_+_34993240 | 0.97 |
ENST00000677647.1
|
SRP54
|
signal recognition particle 54 |
| chr9_-_112332962 | 0.96 |
ENST00000458258.5
ENST00000210227.4 |
PTBP3
|
polypyrimidine tract binding protein 3 |
| chr6_+_29550407 | 0.95 |
ENST00000641137.1
|
OR2I1P
|
olfactory receptor family 2 subfamily I member 1 pseudogene |
| chr2_+_102418642 | 0.95 |
ENST00000264260.6
|
IL18RAP
|
interleukin 18 receptor accessory protein |
| chr9_+_87497675 | 0.95 |
ENST00000472284.5
ENST00000469640.6 |
DAPK1
|
death associated protein kinase 1 |
| chr1_-_74634855 | 0.94 |
ENST00000420661.6
|
ERICH3
|
glutamate rich 3 |
| chr17_-_40665121 | 0.93 |
ENST00000394052.5
|
KRT222
|
keratin 222 |
| chr4_-_46124046 | 0.93 |
ENST00000295452.5
|
GABRG1
|
gamma-aminobutyric acid type A receptor subunit gamma1 |
| chr6_+_26402289 | 0.92 |
ENST00000414912.2
|
BTN3A1
|
butyrophilin subfamily 3 member A1 |
| chr7_-_111784448 | 0.91 |
ENST00000450156.6
|
DOCK4
|
dedicator of cytokinesis 4 |
| chr12_-_9869345 | 0.90 |
ENST00000228438.3
|
CLEC2B
|
C-type lectin domain family 2 member B |
| chr3_+_158801926 | 0.90 |
ENST00000622669.4
ENST00000392813.8 ENST00000415822.8 ENST00000651862.1 ENST00000264266.12 |
MFSD1
|
major facilitator superfamily domain containing 1 |
| chr5_-_95081482 | 0.90 |
ENST00000312216.12
ENST00000512425.5 ENST00000505208.5 ENST00000429576.6 ENST00000508509.5 ENST00000510732.5 |
MCTP1
|
multiple C2 and transmembrane domain containing 1 |
| chr15_+_94355956 | 0.88 |
ENST00000557742.1
|
MCTP2
|
multiple C2 and transmembrane domain containing 2 |
| chr11_-_62754141 | 0.88 |
ENST00000527994.1
ENST00000394807.5 ENST00000673933.1 |
ZBTB3
|
zinc finger and BTB domain containing 3 |
| chr12_-_8066331 | 0.88 |
ENST00000546241.1
ENST00000307637.5 |
C3AR1
|
complement C3a receptor 1 |
| chrX_-_13817027 | 0.87 |
ENST00000493677.5
ENST00000355135.6 ENST00000316715.9 |
GPM6B
|
glycoprotein M6B |
| chr19_-_35812838 | 0.87 |
ENST00000653904.2
|
PRODH2
|
proline dehydrogenase 2 |
| chr6_+_26440472 | 0.86 |
ENST00000494393.5
ENST00000482451.5 ENST00000471353.5 ENST00000361232.7 ENST00000487627.5 ENST00000496719.1 ENST00000244519.7 ENST00000490254.5 ENST00000487272.1 |
BTN3A3
|
butyrophilin subfamily 3 member A3 |
| chr7_-_111784406 | 0.85 |
ENST00000664131.1
ENST00000437129.5 |
DOCK4
|
dedicator of cytokinesis 4 |
| chr1_+_186296267 | 0.85 |
ENST00000533951.5
ENST00000367482.8 ENST00000635041.1 ENST00000367483.8 ENST00000367485.4 ENST00000445192.7 |
PRG4
|
proteoglycan 4 |
| chr9_+_87497852 | 0.84 |
ENST00000408954.8
|
DAPK1
|
death associated protein kinase 1 |
| chrX_-_18672101 | 0.83 |
ENST00000379984.4
|
RS1
|
retinoschisin 1 |
| chr20_+_9514562 | 0.81 |
ENST00000246070.3
|
LAMP5
|
lysosomal associated membrane protein family member 5 |
| chr17_-_59151794 | 0.81 |
ENST00000584089.1
|
SKA2
|
spindle and kinetochore associated complex subunit 2 |
| chr12_+_15546344 | 0.81 |
ENST00000674388.1
ENST00000542557.5 ENST00000445537.6 ENST00000544244.5 ENST00000442921.7 |
PTPRO
|
protein tyrosine phosphatase receptor type O |
| chr6_+_130018565 | 0.81 |
ENST00000361794.7
ENST00000526087.5 ENST00000533560.5 |
L3MBTL3
|
L3MBTL histone methyl-lysine binding protein 3 |
| chr8_+_106726115 | 0.79 |
ENST00000521592.5
|
OXR1
|
oxidation resistance 1 |
| chr18_-_69956670 | 0.78 |
ENST00000583955.5
|
CD226
|
CD226 molecule |
| chrX_+_108044967 | 0.77 |
ENST00000415430.7
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr9_-_6605338 | 0.76 |
ENST00000638654.1
|
GLDC
|
glycine decarboxylase |
| chr2_-_55296361 | 0.76 |
ENST00000647547.1
|
CCDC88A
|
coiled-coil domain containing 88A |
| chr18_-_50819982 | 0.75 |
ENST00000398439.8
ENST00000431965.6 ENST00000436348.6 |
MRO
|
maestro |
| chr4_-_121765104 | 0.72 |
ENST00000643802.2
ENST00000643663.2 |
SMIM43
|
small integral membrane protein 43 |
| chr1_+_84181630 | 0.68 |
ENST00000610457.1
|
PRKACB
|
protein kinase cAMP-activated catalytic subunit beta |
| chr6_-_7313146 | 0.67 |
ENST00000489567.5
ENST00000479365.5 ENST00000462112.1 ENST00000397511.6 ENST00000244763.9 ENST00000474597.5 ENST00000650389.1 |
SSR1
|
signal sequence receptor subunit 1 |
| chr12_-_118359105 | 0.67 |
ENST00000541186.5
ENST00000539872.5 |
TAOK3
|
TAO kinase 3 |
| chr19_+_49513353 | 0.66 |
ENST00000596975.5
|
FCGRT
|
Fc fragment of IgG receptor and transporter |
| chr8_-_109974688 | 0.66 |
ENST00000297404.1
|
KCNV1
|
potassium voltage-gated channel modifier subfamily V member 1 |
| chr17_-_445939 | 0.64 |
ENST00000329099.4
|
RFLNB
|
refilin B |
| chr2_+_206159580 | 0.64 |
ENST00000236957.9
ENST00000392221.5 ENST00000445505.5 |
EEF1B2
|
eukaryotic translation elongation factor 1 beta 2 |
| chr18_-_69957176 | 0.63 |
ENST00000580335.1
|
CD226
|
CD226 molecule |
| chr11_+_72189659 | 0.61 |
ENST00000393681.6
|
FOLR1
|
folate receptor alpha |
| chr14_+_39267377 | 0.61 |
ENST00000556148.5
ENST00000348007.7 |
MIA2
|
MIA SH3 domain ER export factor 2 |
| chr1_-_67134964 | 0.61 |
ENST00000684719.1
ENST00000603691.1 |
C1orf141
|
chromosome 1 open reading frame 141 |
| chr12_+_8092881 | 0.61 |
ENST00000638334.1
|
NECAP1
|
NECAP endocytosis associated 1 |
| chr15_-_19988117 | 0.59 |
ENST00000558565.2
|
IGHV3OR15-7
|
immunoglobulin heavy variable 3/OR15-7 (pseudogene) |
| chr5_+_140821598 | 0.59 |
ENST00000614258.1
ENST00000529859.2 ENST00000529619.5 |
PCDHA5
|
protocadherin alpha 5 |
| chr1_+_224183197 | 0.59 |
ENST00000323699.9
|
DEGS1
|
delta 4-desaturase, sphingolipid 1 |
| chr4_+_26322850 | 0.59 |
ENST00000514675.5
|
RBPJ
|
recombination signal binding protein for immunoglobulin kappa J region |
| chr7_+_150323239 | 0.58 |
ENST00000323078.7
ENST00000493307.1 ENST00000359623.9 |
LRRC61
|
leucine rich repeat containing 61 |
| chr2_-_165203870 | 0.58 |
ENST00000639244.1
ENST00000409101.7 ENST00000668657.1 |
SCN3A
|
sodium voltage-gated channel alpha subunit 3 |
| chr10_-_72523936 | 0.54 |
ENST00000398763.8
ENST00000418483.6 ENST00000489666.2 |
MICU1
|
mitochondrial calcium uptake 1 |
| chr19_+_49513154 | 0.54 |
ENST00000426395.7
ENST00000600273.5 ENST00000599988.5 |
FCGRT
|
Fc fragment of IgG receptor and transporter |
| chr4_-_65670478 | 0.54 |
ENST00000613740.5
ENST00000622150.4 ENST00000511294.1 |
EPHA5
|
EPH receptor A5 |
| chr7_-_83162857 | 0.53 |
ENST00000333891.14
|
PCLO
|
piccolo presynaptic cytomatrix protein |
| chr8_-_90082871 | 0.53 |
ENST00000265431.7
|
CALB1
|
calbindin 1 |
| chr12_-_25195074 | 0.52 |
ENST00000354189.9
ENST00000676236.1 ENST00000545133.5 ENST00000554347.1 ENST00000674567.1 ENST00000395987.8 ENST00000320267.13 ENST00000395990.6 |
CFAP94
|
cilia and flagella associated protein 94 |
| chr11_+_72189528 | 0.52 |
ENST00000312293.9
|
FOLR1
|
folate receptor alpha |
| chr3_+_42979281 | 0.51 |
ENST00000488863.5
ENST00000430121.3 |
GASK1A
|
golgi associated kinase 1A |
| chr4_+_37453914 | 0.51 |
ENST00000381980.9
ENST00000508175.5 |
C4orf19
|
chromosome 4 open reading frame 19 |
| chr9_-_4666347 | 0.51 |
ENST00000381890.9
ENST00000682582.1 |
SPATA6L
|
spermatogenesis associated 6 like |
| chr8_+_49911604 | 0.50 |
ENST00000642164.1
ENST00000644093.1 ENST00000643999.1 ENST00000647073.1 ENST00000646880.1 |
SNTG1
|
syntrophin gamma 1 |
| chr8_+_106726012 | 0.49 |
ENST00000449762.6
ENST00000297447.10 |
OXR1
|
oxidation resistance 1 |
| chr14_+_55027576 | 0.49 |
ENST00000339298.2
|
SOCS4
|
suppressor of cytokine signaling 4 |
| chr6_-_36547400 | 0.49 |
ENST00000229812.8
|
STK38
|
serine/threonine kinase 38 |
| chr3_-_101320558 | 0.48 |
ENST00000193391.8
|
IMPG2
|
interphotoreceptor matrix proteoglycan 2 |
| chr10_+_47300174 | 0.48 |
ENST00000580279.2
|
GDF10
|
growth differentiation factor 10 |
| chr2_-_240557957 | 0.48 |
ENST00000373318.6
ENST00000406958.5 ENST00000272972.7 ENST00000401804.5 ENST00000361678.8 ENST00000391987.5 ENST00000405523.7 |
ANKMY1
|
ankyrin repeat and MYND domain containing 1 |
| chr1_+_177170916 | 0.47 |
ENST00000361539.5
|
BRINP2
|
BMP/retinoic acid inducible neural specific 2 |
| chrX_+_109535775 | 0.47 |
ENST00000218004.5
|
NXT2
|
nuclear transport factor 2 like export factor 2 |
| chr5_-_95081858 | 0.47 |
ENST00000505465.1
|
MCTP1
|
multiple C2 and transmembrane domain containing 1 |
| chr9_-_4666495 | 0.46 |
ENST00000475086.5
|
SPATA6L
|
spermatogenesis associated 6 like |
| chr2_-_88861258 | 0.45 |
ENST00000390240.2
|
IGKJ3
|
immunoglobulin kappa joining 3 |
| chr5_+_151259793 | 0.45 |
ENST00000523004.1
|
GM2A
|
GM2 ganglioside activator |
| chr1_-_207052980 | 0.45 |
ENST00000367084.1
|
YOD1
|
YOD1 deubiquitinase |
| chr7_+_142554828 | 0.45 |
ENST00000611787.1
|
TRBV11-3
|
T cell receptor beta variable 11-3 |
| chr2_+_206159884 | 0.45 |
ENST00000392222.7
|
EEF1B2
|
eukaryotic translation elongation factor 1 beta 2 |
| chr5_+_140806929 | 0.44 |
ENST00000378125.4
ENST00000618834.1 ENST00000530339.2 ENST00000512229.6 ENST00000672575.1 |
PCDHA4
|
protocadherin alpha 4 |
| chr2_+_209653324 | 0.44 |
ENST00000452717.1
|
MAP2
|
microtubule associated protein 2 |
| chr10_+_27532521 | 0.44 |
ENST00000683924.1
|
RAB18
|
RAB18, member RAS oncogene family |
| chr3_-_142029108 | 0.43 |
ENST00000497579.5
|
TFDP2
|
transcription factor Dp-2 |
| chr10_+_89392546 | 0.41 |
ENST00000546318.2
ENST00000371804.4 |
IFIT1
|
interferon induced protein with tetratricopeptide repeats 1 |
| chr12_+_12357418 | 0.41 |
ENST00000298571.6
|
BORCS5
|
BLOC-1 related complex subunit 5 |
| chr8_-_101790934 | 0.40 |
ENST00000523645.5
ENST00000520346.1 ENST00000220931.11 ENST00000522448.5 ENST00000522951.5 ENST00000522252.5 ENST00000519098.5 |
NCALD
|
neurocalcin delta |
| chr1_-_23799561 | 0.40 |
ENST00000445705.1
|
GALE
|
UDP-galactose-4-epimerase |
| chr1_-_23799533 | 0.39 |
ENST00000429356.5
|
GALE
|
UDP-galactose-4-epimerase |
| chr10_-_114144599 | 0.39 |
ENST00000428953.1
|
CCDC186
|
coiled-coil domain containing 186 |
| chr12_+_64405046 | 0.38 |
ENST00000540203.5
|
XPOT
|
exportin for tRNA |
| chr4_-_65670339 | 0.37 |
ENST00000273854.7
|
EPHA5
|
EPH receptor A5 |
| chr6_+_158312459 | 0.36 |
ENST00000367097.8
|
TULP4
|
TUB like protein 4 |
| chr6_+_154039102 | 0.35 |
ENST00000360422.8
ENST00000330432.12 |
OPRM1
|
opioid receptor mu 1 |
| chr7_-_150323725 | 0.35 |
ENST00000477871.1
|
ACTR3C
|
actin related protein 3C |
| chr15_+_44427591 | 0.34 |
ENST00000558791.5
ENST00000260327.9 |
CTDSPL2
|
CTD small phosphatase like 2 |
| chr12_-_118359166 | 0.34 |
ENST00000542902.5
|
TAOK3
|
TAO kinase 3 |
| chr4_+_87799546 | 0.34 |
ENST00000226284.7
|
IBSP
|
integrin binding sialoprotein |
| chrX_+_154304923 | 0.34 |
ENST00000426989.5
ENST00000426203.5 ENST00000369912.2 |
TKTL1
|
transketolase like 1 |
| chr7_+_156640879 | 0.33 |
ENST00000311822.12
|
RNF32
|
ring finger protein 32 |
| chr4_-_67963441 | 0.32 |
ENST00000508048.6
|
TMPRSS11A
|
transmembrane serine protease 11A |
| chr5_+_127649018 | 0.32 |
ENST00000379445.7
|
CTXN3
|
cortexin 3 |
| chr7_-_83162899 | 0.32 |
ENST00000423517.6
|
PCLO
|
piccolo presynaptic cytomatrix protein |
| chr20_-_52105644 | 0.31 |
ENST00000371523.8
|
ZFP64
|
ZFP64 zinc finger protein |
| chr8_-_673547 | 0.31 |
ENST00000522893.1
|
ERICH1
|
glutamate rich 1 |
| chr7_-_150323489 | 0.31 |
ENST00000683684.1
ENST00000478393.5 |
ACTR3C
|
actin related protein 3C |
Network of associatons between targets according to the STRING database.
First level regulatory network of ALX3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.6 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 1.0 | 2.9 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.7 | 2.1 | GO:1902688 | regulation of NAD metabolic process(GO:1902688) |
| 0.6 | 1.9 | GO:0002665 | negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017) |
| 0.5 | 3.8 | GO:0048241 | epinephrine transport(GO:0048241) |
| 0.5 | 2.6 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.5 | 3.0 | GO:0002729 | positive regulation of natural killer cell cytokine production(GO:0002729) |
| 0.5 | 1.5 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 0.5 | 1.4 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 0.4 | 1.2 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.4 | 1.1 | GO:0061713 | neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) |
| 0.3 | 3.8 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.3 | 1.0 | GO:0060003 | copper ion export(GO:0060003) |
| 0.3 | 1.7 | GO:0038112 | interleukin-8-mediated signaling pathway(GO:0038112) |
| 0.3 | 0.8 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.3 | 7.0 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.3 | 0.8 | GO:1903442 | response to methylamine(GO:0036255) response to lipoic acid(GO:1903442) |
| 0.3 | 1.8 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.2 | 1.0 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.2 | 3.5 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.2 | 0.9 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.2 | 0.6 | GO:0061182 | negative regulation of chondrocyte development(GO:0061182) |
| 0.2 | 0.8 | GO:0016062 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
| 0.2 | 0.8 | GO:0036060 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.2 | 1.0 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.2 | 1.2 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 0.2 | 3.3 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.2 | 2.2 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.2 | 1.3 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.2 | 4.1 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 1.0 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.1 | 2.2 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.1 | 3.3 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.1 | 1.8 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.8 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.1 | 1.1 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.1 | 0.5 | GO:1990168 | protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168) |
| 0.1 | 18.7 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 0.4 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 0.1 | 1.6 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 1.5 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.1 | 2.0 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.1 | 2.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 2.1 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 17.6 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.1 | 1.1 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 2.5 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 0.7 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.1 | 0.9 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 0.5 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
| 0.1 | 1.3 | GO:0009157 | deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) |
| 0.1 | 1.0 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.1 | 2.2 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.1 | 2.1 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.1 | 0.3 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.1 | 4.8 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
| 0.0 | 0.7 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.0 | 0.6 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.0 | 0.8 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.0 | 0.5 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.9 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 0.2 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.0 | 0.3 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731) |
| 0.0 | 0.2 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
| 0.0 | 0.5 | GO:0098856 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.0 | 0.4 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.3 | GO:1901189 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.0 | 0.1 | GO:0061358 | negative regulation of Wnt protein secretion(GO:0061358) |
| 0.0 | 0.6 | GO:0090266 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.2 | GO:0043570 | maintenance of DNA repeat elements(GO:0043570) |
| 0.0 | 0.6 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.3 | GO:0014717 | regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901) |
| 0.0 | 1.0 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.0 | 0.1 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.0 | 0.6 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 1.2 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 0.2 | GO:2000773 | negative regulation of cellular senescence(GO:2000773) |
| 0.0 | 2.7 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 3.4 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 2.0 | GO:0002292 | T cell differentiation involved in immune response(GO:0002292) |
| 0.0 | 0.9 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.4 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.0 | 0.9 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.2 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 0.0 | 0.5 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 0.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 1.5 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 0.3 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 1.6 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 1.0 | GO:0002763 | positive regulation of myeloid leukocyte differentiation(GO:0002763) |
| 0.0 | 0.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 5.6 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.3 | 0.8 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 0.2 | 1.4 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.2 | 1.5 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 0.2 | 3.6 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.2 | 0.8 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 0.1 | 1.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 3.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 3.8 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.5 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.1 | 4.1 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 0.8 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 1.0 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.1 | 4.9 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 1.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 0.5 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.1 | 0.4 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.1 | 1.0 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.5 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
| 0.1 | 0.7 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.0 | 0.8 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 0.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.3 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 1.7 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 1.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 1.5 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 1.1 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.7 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 1.4 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.3 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 4.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 1.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 3.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 0.6 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 3.4 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.2 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.0 | 2.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 1.1 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 4.4 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 9.2 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 1.3 | 3.8 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
| 1.0 | 3.8 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 0.6 | 3.3 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.4 | 2.2 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.3 | 1.0 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 0.3 | 1.0 | GO:0004008 | copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682) |
| 0.3 | 1.0 | GO:0015432 | bile acid-exporting ATPase activity(GO:0015432) |
| 0.3 | 1.2 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.3 | 1.7 | GO:0004918 | interleukin-8 receptor activity(GO:0004918) |
| 0.3 | 1.1 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 0.3 | 0.8 | GO:0016642 | glycine dehydrogenase (decarboxylating) activity(GO:0004375) oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor(GO:0016642) vitamin B6 binding(GO:0070279) pyridoxal binding(GO:0070280) |
| 0.2 | 2.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.2 | 0.8 | GO:0003974 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 0.2 | 0.6 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
| 0.2 | 1.3 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.2 | 7.0 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 1.5 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.2 | 1.3 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) |
| 0.2 | 0.5 | GO:0032428 | sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428) |
| 0.1 | 3.1 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 0.9 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.1 | 2.0 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 1.0 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 1.5 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 0.1 | 0.5 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.1 | 1.1 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 29.1 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 1.0 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 0.1 | 3.8 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 1.6 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 0.9 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.3 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.1 | 0.5 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 1.5 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 1.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 1.2 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 0.8 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.0 | 0.8 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 2.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.2 | GO:0052829 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) |
| 0.0 | 0.2 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.0 | 1.4 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 1.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.1 | GO:0038047 | beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047) |
| 0.0 | 0.8 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.0 | 1.9 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 0.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 2.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 1.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.8 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.9 | GO:0071949 | FAD binding(GO:0071949) |
| 0.0 | 1.9 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.8 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 0.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.3 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.0 | 1.1 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 1.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.1 | GO:0052795 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.0 | 2.1 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 3.3 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.3 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 0.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 1.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 3.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 1.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.1 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 3.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.7 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 8.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.5 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 3.3 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.0 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 1.9 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 1.3 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.5 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 2.9 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 1.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 1.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.7 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 7.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.2 | 2.1 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 1.4 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.1 | 3.3 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 2.0 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 3.4 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.1 | 1.5 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.1 | 3.5 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 1.9 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.1 | 1.0 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 3.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 2.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 1.3 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 9.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.7 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 3.0 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 1.7 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.8 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 1.1 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 3.7 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 1.9 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 2.5 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 0.2 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 0.3 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 0.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.3 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |