Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for ATF4

Z-value: 1.24

Motif logo

Transcription factors associated with ATF4

Gene Symbol Gene ID Gene Info
ENSG00000128272.17 activating transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF4hg38_v1_chr22_+_39520553_395206040.232.1e-01Click!

Activity profile of ATF4 motif

Sorted Z-values of ATF4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_40953463 9.01 ENST00000617768.5
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr8_-_38150943 4.25 ENST00000276449.9
steroidogenic acute regulatory protein
chr15_+_40952962 4.16 ENST00000444189.7
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr10_-_14838561 3.94 ENST00000378442.5
cerebral dopamine neurotrophic factor
chr17_+_48055945 3.73 ENST00000580037.1
nuclear factor, erythroid 2 like 1
chr17_+_1762012 3.58 ENST00000571360.5
serpin family F member 1
chr10_+_49299159 3.55 ENST00000374144.8
chromosome 10 open reading frame 71
chr16_-_28539004 3.18 ENST00000395641.2
nuclear protein 1, transcriptional regulator
chr16_-_70289480 3.05 ENST00000261772.13
ENST00000675953.1
ENST00000675691.1
ENST00000675133.1
ENST00000674512.1
ENST00000675045.1
ENST00000675853.1
ENST00000565361.3
ENST00000674963.1
ENST00000674691.1
alanyl-tRNA synthetase 1
chr10_-_14838003 2.88 ENST00000465530.2
cerebral dopamine neurotrophic factor
chr10_-_99430617 2.81 ENST00000370508.7
glutamic-oxaloacetic transaminase 1
chr17_-_81937320 2.68 ENST00000577624.5
ENST00000403172.8
ENST00000619204.4
ENST00000629768.2
pyrroline-5-carboxylate reductase 1
chr17_-_81937221 2.54 ENST00000402252.6
ENST00000583564.5
ENST00000585244.1
ENST00000337943.9
ENST00000579698.5
pyrroline-5-carboxylate reductase 1
chr17_+_1762052 2.49 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
serpin family F member 1
chr16_+_46884323 2.47 ENST00000340124.9
glutamic--pyruvic transaminase 2
chr21_-_30492008 2.46 ENST00000334063.6
keratin associated protein 19-3
chr17_-_81937277 2.39 ENST00000405481.8
ENST00000329875.13
ENST00000585215.5
pyrroline-5-carboxylate reductase 1
chr9_-_92293674 2.37 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
isoleucyl-tRNA synthetase 1
chr1_-_178871060 2.27 ENST00000234816.7
angiopoietin like 1
chr19_+_33374312 2.25 ENST00000585933.2
CCAAT enhancer binding protein gamma
chrX_-_81201886 2.11 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr16_-_28538951 2.06 ENST00000324873.8
nuclear protein 1, transcriptional regulator
chr12_-_49903853 2.05 ENST00000320634.8
Fas apoptotic inhibitory molecule 2
chr11_-_57324907 2.05 ENST00000358252.8
tankyrase 1 binding protein 1
chr1_-_178871022 2.01 ENST00000367629.1
angiopoietin like 1
chr3_-_48088824 1.87 ENST00000439356.2
ENST00000395734.7
ENST00000426837.6
microtubule associated protein 4
chr11_-_3057386 1.85 ENST00000529772.5
ENST00000278224.13
ENST00000380525.9
cysteinyl-tRNA synthetase 1
chr10_+_94089034 1.79 ENST00000676102.1
ENST00000371385.8
phospholipase C epsilon 1
chr10_+_94089067 1.76 ENST00000371375.1
ENST00000675218.1
phospholipase C epsilon 1
chr3_-_48089203 1.69 ENST00000468075.2
ENST00000360240.10
microtubule associated protein 4
chr7_+_30594823 1.66 ENST00000675810.1
ENST00000674815.1
ENST00000454308.6
ENST00000389266.8
ENST00000675693.1
ENST00000675651.1
ENST00000674851.1
glycyl-tRNA synthetase 1
chr8_+_30638562 1.59 ENST00000517349.2
small integral membrane protein 18
chr17_-_42676980 1.55 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chr7_-_56034133 1.55 ENST00000421626.5
phosphoserine phosphatase
chr5_+_33440696 1.51 ENST00000502553.5
ENST00000514259.5
threonyl-tRNA synthetase 1
chr2_-_240820945 1.50 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chr12_-_49904217 1.49 ENST00000550635.6
Fas apoptotic inhibitory molecule 2
chr12_-_46268989 1.48 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
solute carrier family 38 member 1
chr3_-_48088800 1.48 ENST00000423088.5
microtubule associated protein 4
chr1_+_162632454 1.42 ENST00000367921.8
ENST00000367922.7
discoidin domain receptor tyrosine kinase 2
chr2_-_240820205 1.39 ENST00000647731.1
ENST00000648680.1
ENST00000649306.1
ENST00000648129.1
ENST00000498729.9
ENST00000320389.12
ENST00000648364.1
ENST00000647885.1
ENST00000404283.9
ENST00000649096.1
kinesin family member 1A
chr19_+_33373694 1.39 ENST00000284000.9
CCAAT enhancer binding protein gamma
chr21_-_43075831 1.36 ENST00000398158.5
ENST00000398165.8
cystathionine beta-synthase
chr5_+_174724549 1.35 ENST00000239243.7
ENST00000507785.2
msh homeobox 2
chr5_+_33440947 1.34 ENST00000455217.6
ENST00000265112.8
threonyl-tRNA synthetase 1
chr1_+_154272589 1.34 ENST00000457918.6
ENST00000483970.6
ENST00000328703.12
ENST00000435087.1
ENST00000532105.1
HCLS1 associated protein X-1
chr9_-_34665985 1.31 ENST00000416454.5
ENST00000544078.2
ENST00000421828.7
ENST00000423809.5
novel protein
chr21_-_6467509 1.27 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
cystathionine beta-synthase like
chr11_+_62881686 1.27 ENST00000536981.6
ENST00000539891.6
solute carrier family 3 member 2
chr1_-_220046432 1.14 ENST00000609181.5
ENST00000366923.8
glutamyl-prolyl-tRNA synthetase 1
chr12_-_57520480 1.12 ENST00000642841.1
ENST00000547303.5
ENST00000552740.5
ENST00000547526.1
ENST00000346473.8
ENST00000551116.5
novel protein
DNA damage inducible transcript 3
chr11_+_22666604 1.10 ENST00000454584.6
growth arrest specific 2
chr11_-_128867364 1.09 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chrX_-_15314543 1.07 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr5_-_146182591 1.07 ENST00000510191.5
ENST00000674277.1
ENST00000674447.1
ENST00000674270.1
ENST00000394434.7
ENST00000674290.1
ENST00000674398.1
ENST00000674174.1
leucyl-tRNA synthetase 1
chr22_-_29061831 1.06 ENST00000216071.5
chromosome 22 open reading frame 31
chr11_-_128867268 1.06 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr5_-_146182475 1.05 ENST00000674158.1
ENST00000674191.1
ENST00000274562.13
leucyl-tRNA synthetase 1
chr16_+_67660946 1.01 ENST00000602551.5
ENST00000219255.3
ENST00000458121.7
par-6 family cell polarity regulator alpha
chr9_+_78297117 0.98 ENST00000376588.4
phosphoserine aminotransferase 1
chr9_+_78297143 0.97 ENST00000347159.6
phosphoserine aminotransferase 1
chr12_-_46269105 0.97 ENST00000546893.5
solute carrier family 38 member 1
chr18_-_57621741 0.97 ENST00000587194.1
ENST00000591599.5
ENST00000588661.5
ENST00000256854.10
asparaginyl-tRNA synthetase 1
chr7_-_99408548 0.97 ENST00000626285.1
ENST00000350498.8
PDGFA associated protein 1
chr3_-_33645433 0.96 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr10_-_21517825 0.92 ENST00000444772.3
SKI/DACH domain containing 1
chr1_-_216805367 0.86 ENST00000360012.7
estrogen related receptor gamma
chr10_+_61901678 0.84 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr8_-_126557691 0.84 ENST00000652209.1
LRAT domain containing 2
chr10_-_112183698 0.83 ENST00000369425.5
ENST00000348367.9
glycerol-3-phosphate acyltransferase, mitochondrial
chr12_+_10212867 0.80 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr20_+_23362144 0.80 ENST00000338121.10
ENST00000424216.1
GDNF inducible zinc finger protein 1
chr17_+_58238694 0.78 ENST00000581008.1
lactoperoxidase
chr5_+_140547632 0.76 ENST00000310331.3
eukaryotic translation initiation factor 4E binding protein 3
chr5_+_33441062 0.74 ENST00000626210.1
ENST00000627006.2
threonyl-tRNA synthetase 1
chr19_+_11239602 0.74 ENST00000252453.12
angiopoietin like 8
chr3_-_33645253 0.70 ENST00000333778.10
cytoplasmic linker associated protein 2
chr1_-_206970457 0.65 ENST00000324852.9
ENST00000450945.3
ENST00000400962.8
Fc fragment of IgA and IgM receptor
chr6_+_72366730 0.64 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr10_+_14838365 0.63 ENST00000441647.1
heat shock protein family A (Hsp70) member 14
chr7_-_138701352 0.62 ENST00000421622.5
ENST00000674285.1
SVOP like
chr11_-_17533869 0.60 ENST00000526181.1
USH1 protein network component harmonin
chr12_-_24949026 0.60 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
branched chain amino acid transaminase 1
chr1_-_32817311 0.59 ENST00000373477.9
ENST00000675785.1
tyrosyl-tRNA synthetase 1
chr5_+_144205250 0.58 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr12_+_57520698 0.58 ENST00000548887.5
methyl-CpG binding domain protein 6
chrX_+_24054931 0.55 ENST00000253039.9
ENST00000423068.1
eukaryotic translation initiation factor 2 subunit gamma
chr4_-_152536045 0.55 ENST00000603548.6
ENST00000281708.10
F-box and WD repeat domain containing 7
chr12_+_57230336 0.54 ENST00000555773.5
ENST00000554975.5
ENST00000449049.7
serine hydroxymethyltransferase 2
chr10_+_14838288 0.51 ENST00000640019.3
ENST00000493178.1
ENST00000378372.8
novel protein
heat shock protein family A (Hsp70) member 14
chr1_+_52056255 0.47 ENST00000489308.6
basic transcription factor 3 like 4
chr11_+_22667069 0.44 ENST00000533363.5
growth arrest specific 2
chr12_+_10212836 0.43 ENST00000421801.6
ENST00000544284.5
GABA type A receptor associated protein like 1
chr5_+_44808930 0.43 ENST00000507110.6
mitochondrial ribosomal protein S30
chrX_-_33339525 0.42 ENST00000288447.9
dystrophin
chr12_+_106601137 0.41 ENST00000357881.8
regulatory factor X4
chr19_-_54081365 0.40 ENST00000432826.2
T cell-interacting, activating receptor on myeloid cells 1
chr10_+_100347225 0.38 ENST00000370355.3
stearoyl-CoA desaturase
chr12_+_57230301 0.38 ENST00000553474.5
serine hydroxymethyltransferase 2
chr17_-_79993634 0.37 ENST00000571872.1
TBC1 domain family member 16
chr3_+_148697784 0.37 ENST00000497524.5
ENST00000418473.7
ENST00000349243.8
ENST00000404754.2
angiotensin II receptor type 1
chr12_+_57230274 0.35 ENST00000557427.5
serine hydroxymethyltransferase 2
chr19_+_48755512 0.34 ENST00000593756.6
fibroblast growth factor 21
chr2_+_6978624 0.30 ENST00000433456.1
ring finger protein 144A
chr19_+_48756067 0.28 ENST00000222157.5
fibroblast growth factor 21
chr1_+_233904656 0.28 ENST00000366618.8
solute carrier family 35 member F3
chr19_-_8698789 0.24 ENST00000324436.5
actin like 9
chr19_-_8698705 0.24 ENST00000612068.1
actin like 9
chr2_-_215436061 0.24 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr12_+_57229694 0.24 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
serine hydroxymethyltransferase 2
chr12_+_57230124 0.23 ENST00000553529.5
ENST00000554310.5
serine hydroxymethyltransferase 2
chr7_-_48029102 0.23 ENST00000297325.9
ENST00000412142.5
ENST00000395572.6
Sad1 and UNC84 domain containing 3
chr7_+_48171451 0.23 ENST00000435803.6
ATP binding cassette subfamily A member 13
chr1_+_239719542 0.23 ENST00000448020.1
cholinergic receptor muscarinic 3
chr1_-_44031352 0.21 ENST00000372306.7
ENST00000475075.6
solute carrier family 6 member 9
chr7_-_18027839 0.20 ENST00000506618.5
phosphoribosyl pyrophosphate synthetase 1 like 1
chr11_+_119084873 0.18 ENST00000652429.1
ENST00000442944.7
ENST00000537841.5
ENST00000542729.5
ENST00000546302.6
ENST00000536813.6
ENST00000544387.5
ENST00000543090.5
hydroxymethylbilane synthase
chr12_+_10212483 0.18 ENST00000545859.5
GABA type A receptor associated protein like 1
chr14_-_91947383 0.17 ENST00000267620.14
fibulin 5
chr11_+_119085200 0.16 ENST00000650101.1
hydroxymethylbilane synthase
chr16_-_705726 0.16 ENST00000397621.6
ENST00000324361.9
F-box and leucine rich repeat protein 16
chr19_+_1450113 0.15 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC regulator of WNT signaling pathway 2
chr1_-_167914089 0.14 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
adenylate cyclase 10
chr11_-_77474087 0.13 ENST00000356341.8
p21 (RAC1) activated kinase 1
chr12_+_56468561 0.13 ENST00000338146.7
SPRY domain containing 4
chr1_-_19923617 0.13 ENST00000375116.3
phospholipase A2 group IIE
chr22_+_41833079 0.11 ENST00000612482.4
ENST00000361204.9
sterol regulatory element binding transcription factor 2
chr12_+_57230086 0.10 ENST00000414700.7
ENST00000557703.5
serine hydroxymethyltransferase 2
chr9_+_36169382 0.05 ENST00000335119.4
calicin
chr1_+_162631984 0.04 ENST00000415555.5
discoidin domain receptor tyrosine kinase 2
chr2_+_46542474 0.04 ENST00000238738.9
ras homolog family member Q
chr5_+_154755272 0.02 ENST00000518297.6
La ribonucleoprotein 1, translational regulator
chr6_+_159890964 0.01 ENST00000434562.2
ENST00000674077.2
novel transcript
MAS1 proto-oncogene, G protein-coupled receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0018963 phthalate metabolic process(GO:0018963)
0.9 2.8 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.7 6.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.7 5.0 GO:0051012 microtubule sliding(GO:0051012)
0.7 6.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.6 13.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.5 3.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.5 2.5 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.4 1.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.4 2.6 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.4 3.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.3 1.4 GO:0051795 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795)
0.3 5.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 5.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.2 0.6 GO:1904106 protein localization to microvillus(GO:1904106)
0.2 3.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 1.3 GO:0060356 leucine import(GO:0060356)
0.2 1.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 3.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.5 GO:2000639 negative regulation of triglyceride biosynthetic process(GO:0010868) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.6 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 0.6 GO:1904640 response to methionine(GO:1904640)
0.1 1.0 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 6.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 3.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.2 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 2.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 2.9 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 2.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 2.5 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0015888 thiamine transport(GO:0015888)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 2.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.7 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 2.5 GO:0031424 keratinization(GO:0031424)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990617 CHOP-ATF4 complex(GO:1990617)
0.4 4.3 GO:0030061 mitochondrial crista(GO:0030061)
0.3 6.1 GO:0043203 axon hillock(GO:0043203)
0.1 1.8 GO:0070552 BRISC complex(GO:0070552)
0.1 1.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 13.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.9 GO:1904115 axon cytoplasm(GO:1904115)
0.0 5.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 4.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 2.8 GO:0043679 axon terminus(GO:0043679)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 7.6 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 13.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.0 7.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.9 2.8 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.8 2.5 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.4 2.6 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.3 1.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 1.8 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 2.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 2.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 4.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.6 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 3.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 3.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.0 GO:0008483 transaminase activity(GO:0008483)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.6 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 1.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 2.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140) leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 1.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 3.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 6.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 6.0 GO:0008083 growth factor activity(GO:0008083)
0.0 1.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.0 GO:0032427 GBD domain binding(GO:0032427)
0.0 6.4 GO:0008017 microtubule binding(GO:0008017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 3.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 4.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine