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Illumina Body Map 2 (GSE30611)

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Results for ATF5

Z-value: 1.16

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ENSG00000169136.12 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg38_v1_chr19_+_49928702_49928769-0.163.7e-01Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_53995929 8.20 ENST00000422805.1
brain enriched myelin associated protein 1
chr14_+_23377001 4.91 ENST00000342473.8
ENST00000397227.7
ENST00000339180.9
ENST00000555731.5
CKLF like MARVEL transmembrane domain containing 5
chr14_+_23376765 3.84 ENST00000649278.1
CKLF like MARVEL transmembrane domain containing 5
chr14_+_23376786 3.60 ENST00000359320.7
CKLF like MARVEL transmembrane domain containing 5
chr5_-_39219555 3.56 ENST00000512982.4
ENST00000351578.12
ENST00000509072.5
ENST00000504542.1
ENST00000506557.5
FYN binding protein 1
chr22_-_36819479 3.38 ENST00000216200.9
parvalbumin
chrX_-_13817346 3.36 ENST00000356942.9
glycoprotein M6B
chr8_-_130016622 3.31 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr4_-_175812236 3.30 ENST00000505375.5
glycoprotein M6A
chr8_-_130016414 3.28 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B
chr10_-_102419693 3.07 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr8_-_130016395 2.99 ENST00000523509.5
CYFIP related Rac1 interactor B
chr14_+_23377136 2.98 ENST00000382809.2
CKLF like MARVEL transmembrane domain containing 5
chr2_-_86790900 2.97 ENST00000283635.8
CD8a molecule
chr1_+_177170916 2.93 ENST00000361539.5
BMP/retinoic acid inducible neural specific 2
chr10_-_102419934 2.93 ENST00000406432.5
pleckstrin and Sec7 domain containing
chrX_-_13817027 2.76 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr14_+_92323154 2.65 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chrX_-_13817279 2.63 ENST00000475307.1
glycoprotein M6B
chr12_+_9971402 2.62 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
C-type lectin domain family 12 member A
chr6_-_31546552 2.62 ENST00000303892.10
ENST00000376151.4
ATPase H+ transporting V1 subunit G2
chr18_-_3845321 2.58 ENST00000539435.5
ENST00000400147.6
DLG associated protein 1
chr6_+_71886900 2.56 ENST00000517960.5
ENST00000518273.5
ENST00000522291.5
ENST00000521978.5
ENST00000520567.5
ENST00000264839.11
regulating synaptic membrane exocytosis 1
chr2_+_190469486 2.54 ENST00000444317.1
major facilitator superfamily domain containing 6
chr4_+_158521714 2.35 ENST00000613319.4
ENST00000423548.5
ENST00000448688.6
relaxin family peptide receptor 1
chr12_+_9971512 2.35 ENST00000350667.4
C-type lectin domain family 12 member A
chr11_-_125481585 2.30 ENST00000577924.1
fasciculation and elongation protein zeta 1
chr5_-_149063089 2.28 ENST00000512049.5
SH3 domain and tetratricopeptide repeats 2
chrX_+_123184260 2.27 ENST00000620443.2
ENST00000622768.5
ENST00000611689.4
glutamate ionotropic receptor AMPA type subunit 3
chr5_-_149063021 2.27 ENST00000515425.6
SH3 domain and tetratricopeptide repeats 2
chr1_+_202122910 2.26 ENST00000682545.1
ENST00000367282.6
ENST00000682887.1
G protein-coupled receptor 37 like 1
chr2_-_25982681 2.20 ENST00000405914.1
kinesin family member 3C
chr1_+_202122881 2.20 ENST00000683302.1
ENST00000683557.1
G protein-coupled receptor 37 like 1
chr17_+_46713149 2.20 ENST00000576346.5
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr5_+_111223905 2.16 ENST00000512453.5
calcium/calmodulin dependent protein kinase IV
chr2_-_25982471 2.14 ENST00000264712.8
kinesin family member 3C
chr7_-_3043838 2.13 ENST00000356408.3
ENST00000396946.9
caspase recruitment domain family member 11
chr10_+_110005804 2.12 ENST00000360162.7
adducin 3
chr8_-_130016536 2.11 ENST00000519020.5
CYFIP related Rac1 interactor B
chr8_+_20197369 2.05 ENST00000276390.7
ENST00000519667.1
ATPase H+ transporting V1 subunit B2
chr4_-_82798735 2.00 ENST00000273908.4
ENST00000319540.9
stearoyl-CoA desaturase 5
chr14_+_79280263 1.88 ENST00000555387.1
neurexin 3
chr17_-_7205116 1.81 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr2_+_172860038 1.81 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr1_+_35557435 1.81 ENST00000373253.7
neurochondrin
chr11_-_84720876 1.76 ENST00000648622.1
discs large MAGUK scaffold protein 2
chr14_+_41606865 1.74 ENST00000298119.9
leucine rich repeat and fibronectin type III domain containing 5
chr18_-_3845292 1.73 ENST00000400145.6
DLG associated protein 1
chr1_+_35557768 1.72 ENST00000356090.8
ENST00000373243.7
neurochondrin
chr14_+_79279906 1.71 ENST00000428277.6
neurexin 3
chr15_+_80441229 1.70 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
aryl hydrocarbon receptor nuclear translocator 2
chr3_-_183427977 1.70 ENST00000473233.5
MCF.2 cell line derived transforming sequence-like 2
chr5_+_83471764 1.69 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr1_-_183418364 1.65 ENST00000287713.7
nicotinamide nucleotide adenylyltransferase 2
chr11_+_63681483 1.59 ENST00000339997.8
ENST00000540798.5
ENST00000545432.5
ENST00000543552.5
ENST00000377819.10
ENST00000537981.5
reticulon 3
chr11_+_63681444 1.56 ENST00000341307.6
ENST00000356000.7
ENST00000542238.5
reticulon 3
chr11_+_92224801 1.54 ENST00000525166.6
FAT atypical cadherin 3
chr16_-_30029429 1.54 ENST00000564806.1
TLC domain containing 3B
chr11_+_63681573 1.54 ENST00000354497.4
reticulon 3
chr18_-_34224871 1.50 ENST00000261592.10
nucleolar protein 4
chr12_-_54384460 1.48 ENST00000549937.5
zinc finger protein 385A
chr4_+_133149278 1.48 ENST00000264360.7
protocadherin 10
chr14_-_39432414 1.48 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr12_-_54384687 1.45 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr11_-_129192291 1.44 ENST00000682385.1
Rho GTPase activating protein 32
chr4_+_133149307 1.44 ENST00000618019.1
protocadherin 10
chr4_+_158521872 1.44 ENST00000307765.10
relaxin family peptide receptor 1
chr20_+_59604527 1.43 ENST00000371015.6
phosphatase and actin regulator 3
chr5_+_83471668 1.43 ENST00000342785.8
ENST00000343200.9
versican
chr12_-_54384659 1.42 ENST00000551771.5
zinc finger protein 385A
chr5_+_83471925 1.42 ENST00000502527.2
versican
chr5_-_20575850 1.42 ENST00000507958.5
cadherin 18
chr11_-_129192198 1.40 ENST00000310343.13
Rho GTPase activating protein 32
chr2_-_144521042 1.40 ENST00000637267.2
zinc finger E-box binding homeobox 2
chr1_+_66534107 1.39 ENST00000371037.9
ENST00000684651.1
SH3GL interacting endocytic adaptor 1
chr5_+_83471736 1.36 ENST00000265077.8
versican
chrX_+_12137409 1.35 ENST00000672010.1
FERM and PDZ domain containing 4
chr12_-_16608073 1.35 ENST00000441439.6
LIM domain only 3
chr4_+_158521937 1.34 ENST00000343542.9
ENST00000470033.2
relaxin family peptide receptor 1
chr16_-_30012294 1.33 ENST00000564979.5
ENST00000563378.5
double C2 domain alpha
chr19_-_38426195 1.33 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr14_-_23578756 1.33 ENST00000397118.7
ENST00000356300.9
junctophilin 4
chr6_-_62286161 1.31 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr8_+_35235467 1.30 ENST00000404895.7
unc-5 netrin receptor D
chr9_-_23826231 1.29 ENST00000397312.7
ELAV like RNA binding protein 2
chr1_+_66534014 1.29 ENST00000684664.1
ENST00000682416.1
ENST00000683499.1
SH3GL interacting endocytic adaptor 1
chr1_+_66534082 1.27 ENST00000683257.1
ENST00000684083.1
ENST00000682938.1
ENST00000683581.1
ENST00000682293.1
SH3GL interacting endocytic adaptor 1
chr9_+_79573162 1.27 ENST00000425506.5
TLE family member 4, transcriptional corepressor
chr9_+_101185029 1.27 ENST00000395056.2
phospholipid phosphatase related 1
chr19_-_14979676 1.25 ENST00000598504.5
ENST00000597262.1
solute carrier family 1 member 6
chr17_+_49210699 1.19 ENST00000225941.6
ABI family member 3
chr14_+_79280056 1.18 ENST00000676811.1
neurexin 3
chr2_-_213151590 1.16 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr16_+_31259922 1.15 ENST00000648685.1
ENST00000544665.9
integrin subunit alpha M
chr22_+_37282464 1.13 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
cytohesin 4
chr16_+_28931942 1.13 ENST00000324662.8
ENST00000538922.8
CD19 molecule
chr3_-_183428085 1.12 ENST00000447025.6
ENST00000414362.6
MCF.2 cell line derived transforming sequence-like 2
chr22_-_30266839 1.08 ENST00000403463.1
ENST00000215781.3
oncostatin M
chr11_-_40294089 1.07 ENST00000278198.2
leucine rich repeat containing 4C
chr1_+_206406377 1.03 ENST00000605476.5
SLIT-ROBO Rho GTPase activating protein 2
chr19_-_14979848 1.00 ENST00000594383.2
solute carrier family 1 member 6
chrX_+_56563569 0.98 ENST00000338222.7
ubiquilin 2
chr2_-_100142575 0.96 ENST00000317233.8
ENST00000672204.1
ENST00000416492.5
ENST00000672857.1
ENST00000672756.2
AF4/FMR2 family member 3
chr14_+_79279403 0.95 ENST00000281127.11
neurexin 3
chrX_+_132023580 0.93 ENST00000496850.1
serine/threonine kinase 26
chrX_-_44542833 0.90 ENST00000378045.5
FUN14 domain containing 1
chr15_+_74826603 0.89 ENST00000395018.6
complexin 3
chr1_-_54406385 0.89 ENST00000610401.5
single stranded DNA binding protein 3
chr10_-_7411451 0.86 ENST00000683762.1
ENST00000379713.8
ENST00000682180.1
Scm like with four mbt domains 2
chr7_-_78771058 0.86 ENST00000628781.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_106726012 0.84 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr8_-_21788159 0.84 ENST00000517892.5
ENST00000518077.5
GDNF family receptor alpha 2
chr10_-_7410973 0.84 ENST00000684547.1
ENST00000673876.1
ENST00000397167.6
Scm like with four mbt domains 2
chr12_-_16608183 0.83 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr14_+_79279681 0.83 ENST00000679122.1
neurexin 3
chr6_+_101181254 0.82 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr17_+_18858068 0.82 ENST00000536323.5
ENST00000419284.6
ENST00000412418.5
ENST00000575228.5
ENST00000268835.7
ENST00000575102.5
phosphoribosyl pyrophosphate synthetase associated protein 2
chr1_+_121184964 0.81 ENST00000367123.8
SLIT-ROBO Rho GTPase activating protein 2C
chr17_+_49210387 0.80 ENST00000419580.6
ABI family member 3
chr7_+_142580911 0.80 ENST00000621184.1
T cell receptor beta variable 12-5
chr9_+_124261427 0.80 ENST00000373596.5
ENST00000425237.5
NIMA related kinase 6
chr7_-_116030750 0.79 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr14_+_32078228 0.78 ENST00000556191.5
ENST00000554090.1
Rho GTPase activating protein 5
chr17_+_35587239 0.77 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr1_+_66533948 0.76 ENST00000684178.1
SH3GL interacting endocytic adaptor 1
chr7_-_78771108 0.76 ENST00000626691.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_+_123525822 0.75 ENST00000322282.11
ENST00000529750.5
GRAM domain containing 1B
chr7_-_78770859 0.75 ENST00000636717.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_106726115 0.75 ENST00000521592.5
oxidation resistance 1
chr20_+_59163810 0.72 ENST00000371030.4
zinc finger protein 831
chr11_+_67375985 0.71 ENST00000621995.1
RAD9 checkpoint clamp component A
chr8_-_21788853 0.70 ENST00000524240.6
GDNF family receptor alpha 2
chr11_+_27055215 0.70 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr6_+_113857333 0.69 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr17_-_49210567 0.69 ENST00000507680.6
G protein subunit gamma transducin 2
chr10_+_102419189 0.69 ENST00000432590.5
F-box and leucine rich repeat protein 15
chr7_-_78771265 0.68 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_139293660 0.67 ENST00000512876.5
ENST00000513678.5
matrin 3
chrX_-_47629845 0.67 ENST00000469388.1
ENST00000396992.8
ENST00000377005.6
complement factor properdin
chr2_+_72916183 0.66 ENST00000394111.6
empty spiracles homeobox 1
chr16_+_50279515 0.65 ENST00000569265.1
adenylate cyclase 7
chr15_-_75579248 0.64 ENST00000306726.6
ENST00000618819.5
protein tyrosine phosphatase non-receptor type 9
chrX_+_132023294 0.62 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chrX_+_123962010 0.61 ENST00000428941.5
stromal antigen 2
chr1_+_66534171 0.60 ENST00000682762.1
ENST00000424320.6
SH3GL interacting endocytic adaptor 1
chr1_+_206203541 0.60 ENST00000573034.8
SLIT-ROBO Rho GTPase activating protein 2
chr16_-_72094371 0.60 ENST00000426362.6
thioredoxin like 4B
chr11_+_63888515 0.59 ENST00000509502.6
ENST00000512060.1
microtubule affinity regulating kinase 2
chr15_+_63189554 0.58 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr5_+_111223614 0.57 ENST00000508074.5
calcium/calmodulin dependent protein kinase IV
chrX_+_123184153 0.57 ENST00000616590.4
glutamate ionotropic receptor AMPA type subunit 3
chr1_-_151346846 0.56 ENST00000436271.5
ENST00000450506.5
ENST00000422595.5
regulatory factor X5
chr8_-_109680812 0.56 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
syntabulin
chr5_+_139293939 0.55 ENST00000508689.1
ENST00000514528.5
matrin 3
chr5_+_139293700 0.55 ENST00000504045.5
ENST00000504311.5
ENST00000502499.5
matrin 3
chrX_+_147943245 0.54 ENST00000463120.2
FMRP translational regulator 1
chr19_+_32405758 0.54 ENST00000392250.7
dpy-19 like C-mannosyltransferase 3
chrX_+_123961304 0.53 ENST00000371160.5
ENST00000435103.5
stromal antigen 2
chr8_+_38820332 0.53 ENST00000518809.5
ENST00000520611.1
transforming acidic coiled-coil containing protein 1
chr7_-_102592444 0.53 ENST00000514917.3
novel protein
chr20_+_56412249 0.51 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr12_-_12338674 0.51 ENST00000545735.1
MANSC domain containing 1
chr6_-_87702221 0.50 ENST00000257787.6
akirin 2
chr1_-_156490599 0.49 ENST00000360595.7
myocyte enhancer factor 2D
chr22_+_19131271 0.48 ENST00000399635.4
testis specific serine kinase 2
chr16_-_72093598 0.47 ENST00000268483.8
thioredoxin like 4B
chr17_+_34579576 0.46 ENST00000631683.2
transmembrane protein 132E
chr5_+_139293728 0.46 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr19_-_38426162 0.46 ENST00000587738.2
ENST00000586305.5
RAS guanyl releasing protein 4
chr19_-_43781249 0.44 ENST00000615047.4
potassium calcium-activated channel subfamily N member 4
chr1_-_145095528 0.44 ENST00000612199.4
ENST00000641863.1
SLIT-ROBO Rho GTPase activating protein 2B
chr1_+_215005847 0.43 ENST00000391895.6
potassium two pore domain channel subfamily K member 2
chr17_+_35587478 0.42 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr19_-_43780957 0.41 ENST00000648319.1
potassium calcium-activated channel subfamily N member 4
chr2_-_40512361 0.41 ENST00000403092.5
solute carrier family 8 member A1
chr6_-_31897675 0.41 ENST00000375530.8
ENST00000375537.8
euchromatic histone lysine methyltransferase 2
chr8_+_78516329 0.40 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr17_-_75153826 0.40 ENST00000481647.5
ENST00000470924.5
Jupiter microtubule associated homolog 1
chr14_-_65102383 0.39 ENST00000341653.6
MYC associated factor X
chrX_+_123961696 0.38 ENST00000371145.8
ENST00000371157.7
ENST00000371144.7
stromal antigen 2
chr7_-_100464248 0.38 ENST00000332375.4
chromosome 7 open reading frame 61
chr11_+_62728642 0.38 ENST00000532583.1
tetratricopeptide repeat domain 9C
chr7_+_133253064 0.38 ENST00000393161.6
ENST00000253861.5
exocyst complex component 4
chr5_-_135452318 0.37 ENST00000537858.2
TIFA inhibitor
chr2_-_55050518 0.37 ENST00000317610.11
ENST00000357732.8
reticulon 4
chrX_-_136780925 0.37 ENST00000250617.7
Rac/Cdc42 guanine nucleotide exchange factor 6
chr1_-_153946652 0.36 ENST00000361217.9
DENN domain containing 4B
chr3_+_19947316 0.36 ENST00000422242.1
RAB5A, member RAS oncogene family
chr19_-_54360949 0.36 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr16_-_72093557 0.36 ENST00000562153.5
thioredoxin like 4B
chr8_+_99013247 0.35 ENST00000441350.2
ENST00000357162.7
ENST00000358544.7
vacuolar protein sorting 13 homolog B
chr6_+_87155537 0.34 ENST00000369577.8
ENST00000518845.1
ENST00000339907.8
ENST00000496806.2
zinc finger protein 292
chr1_-_205084460 0.34 ENST00000367167.4
transmembrane protein 81
chr22_-_26479664 0.34 ENST00000402105.7
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2
chr1_-_151346806 0.34 ENST00000392746.7
regulatory factor X5
chr2_-_196171565 0.33 ENST00000263955.9
serine/threonine kinase 17b
chr6_-_30686624 0.33 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr10_+_101354028 0.33 ENST00000393441.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chrX_-_119852948 0.33 ENST00000276201.7
ENST00000345865.6
UPF3B regulator of nonsense mediated mRNA decay
chr20_+_56412112 0.33 ENST00000360314.7
Cas scaffold protein family member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.7 3.0 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.7 4.4 GO:0070889 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.7 8.7 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 0.9 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.4 5.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.4 1.7 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.4 4.5 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.4 2.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.3 5.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 2.4 GO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.2 1.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.2 4.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 5.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 2.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 3.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 1.6 GO:0035494 SNARE complex disassembly(GO:0035494)
0.2 7.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 6.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 7.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.6 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 1.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 2.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 1.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 2.1 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 0.4 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.3 GO:0015847 putrescine transport(GO:0015847)
0.1 0.5 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 1.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 1.8 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 4.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.3 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.1 0.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 2.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 1.6 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 2.6 GO:0097186 amelogenesis(GO:0097186)
0.1 1.3 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.1 1.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 4.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.5 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.7 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 3.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 1.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 3.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 3.5 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 1.8 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:0007512 adult heart development(GO:0007512)
0.0 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 2.0 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 5.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 1.0 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 4.9 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 1.1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.0 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 1.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 6.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 3.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 5.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 2.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.5 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 1.6 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 1.3 GO:0030314 junctional membrane complex(GO:0030314)
0.1 3.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 2.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.6 GO:0051286 cell tip(GO:0051286)
0.1 6.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.5 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 2.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 2.6 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 2.7 GO:0097542 ciliary tip(GO:0097542)
0.0 5.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 5.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 3.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 11.4 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 2.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 15.5 GO:0030425 dendrite(GO:0030425)
0.0 8.2 GO:0098793 presynapse(GO:0098793)
0.0 4.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 1.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.9 GO:0045121 membrane raft(GO:0045121)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0036505 prosaposin receptor activity(GO:0036505)
0.4 1.7 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.4 2.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 2.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 8.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 3.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 2.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 0.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 1.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 7.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 2.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 5.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 1.1 GO:0001851 complement component C3b binding(GO:0001851)
0.1 1.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 3.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 2.0 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.2 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.6 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 2.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 5.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.8 GO:0030552 cAMP binding(GO:0030552)
0.0 4.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0050421 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 7.0 GO:0005125 cytokine activity(GO:0005125)
0.0 0.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 5.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 2.6 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 3.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 2.8 GO:0035091 phosphatidylinositol binding(GO:0035091)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 5.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 5.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 5.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.1 REACTOME KINESINS Genes involved in Kinesins
0.1 3.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 3.4 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 4.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 5.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 3.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions