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Illumina Body Map 2 (GSE30611)
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Results for AUGGCUU
Z-value: 1.48
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miRNA associated with seed AUGGCUU
Network of associatons between targets according to the STRING database.
First level regulatory network of AUGGCUU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 15.4 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.6 | 8.8 | GO:0046549 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 2.1 | 8.6 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.3 | 8.1 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.2 | 7.5 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.1 | 7.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.1 | 6.8 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 6.4 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 6.1 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.2 | 5.8 | GO:0060384 | innervation(GO:0060384) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 13.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 1.7 | 13.3 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.2 | 8.9 | GO:0033268 | node of Ranvier(GO:0033268) |
| 2.2 | 8.8 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.5 | 8.6 | GO:0005883 | neurofilament(GO:0005883) |
| 0.3 | 8.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 7.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 6.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 6.0 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.6 | 5.9 | GO:0044305 | calyx of Held(GO:0044305) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 20.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 9.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.3 | 9.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 1.1 | 8.8 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.0 | 8.6 | GO:0008017 | microtubule binding(GO:0008017) |
| 1.1 | 7.5 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 6.3 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.6 | 5.7 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 5.6 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.5 | 5.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.9 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 7.8 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.2 | 7.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 5.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 3.7 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 3.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 2.6 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.1 | 2.5 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.8 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 1.4 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 17.1 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.3 | 13.8 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.2 | 12.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 12.2 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.1 | 10.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 7.3 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 5.0 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 3.8 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 2.7 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 2.4 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |