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Illumina Body Map 2 (GSE30611)

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Results for BBX

Z-value: 0.89

Motif logo

Transcription factors associated with BBX

Gene Symbol Gene ID Gene Info
ENSG00000114439.19 BBX high mobility group box domain containing

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BBXhg38_v1_chr3_+_107524357_1075243760.115.5e-01Click!

Activity profile of BBX motif

Sorted Z-values of BBX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_154563003 5.60 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr7_-_16881967 3.47 ENST00000402239.7
ENST00000310398.7
ENST00000414935.1
anterior gradient 3, protein disulphide isomerase family member
chr16_+_56638659 3.18 ENST00000290705.12
metallothionein 1A
chr11_+_60699605 3.18 ENST00000300226.7
membrane spanning 4-domains A8
chr2_-_215393126 2.53 ENST00000456923.5
fibronectin 1
chr9_-_92404559 2.49 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr7_-_16833411 2.41 ENST00000412973.1
anterior gradient 2, protein disulphide isomerase family member
chr11_+_60699669 2.27 ENST00000529752.5
membrane spanning 4-domains A8
chr3_-_58666765 2.27 ENST00000358781.7
FAM3 metabolism regulating signaling molecule D
chr2_+_102311546 2.20 ENST00000233954.6
ENST00000447231.5
interleukin 1 receptor like 1
chr9_-_92404690 2.06 ENST00000447356.1
osteoglycin
chr3_+_151814102 1.98 ENST00000232892.12
arylacetamide deacetylase
chr1_-_58577244 1.91 ENST00000371225.4
tumor associated calcium signal transducer 2
chr7_+_117480052 1.65 ENST00000426809.5
ENST00000649781.1
CF transmembrane conductance regulator
chr2_+_102311502 1.63 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr6_-_25874212 1.56 ENST00000361703.10
ENST00000397060.8
solute carrier family 17 member 3
chr7_+_117480011 1.52 ENST00000649406.1
ENST00000648260.1
ENST00000003084.11
CF transmembrane conductance regulator
chr9_+_35161951 1.51 ENST00000617908.4
ENST00000619578.4
unc-13 homolog B
chr3_+_148865288 1.35 ENST00000296046.4
carboxypeptidase A3
chr6_+_31927486 1.33 ENST00000442278.6
complement C2
chr3_-_169147734 1.30 ENST00000464456.5
MDS1 and EVI1 complex locus
chr4_-_185775271 1.29 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr6_-_49744434 1.25 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr6_+_121437378 1.19 ENST00000650427.1
ENST00000647564.1
gap junction protein alpha 1
chr6_-_49744378 1.18 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr4_-_103099811 1.14 ENST00000504285.5
ENST00000296424.9
3-hydroxybutyrate dehydrogenase 2
chr3_+_151814069 1.13 ENST00000488869.1
arylacetamide deacetylase
chr4_-_185775890 1.11 ENST00000437304.6
sorbin and SH3 domain containing 2
chr3_-_146528750 1.07 ENST00000483300.5
phospholipid scramblase 1
chr9_+_35162000 1.06 ENST00000396787.5
ENST00000378495.7
ENST00000635942.1
ENST00000378496.8
unc-13 homolog B
chr15_+_49423233 1.05 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr15_+_40351026 0.99 ENST00000448599.2
proline, histidine and glycine rich 1
chr4_-_103099852 0.99 ENST00000509245.1
3-hydroxybutyrate dehydrogenase 2
chr9_-_92482499 0.99 ENST00000375544.7
asporin
chr6_+_31927510 0.97 ENST00000447952.6
complement C2
chr1_+_192575765 0.95 ENST00000469578.2
ENST00000367459.8
regulator of G protein signaling 1
chr4_-_185812209 0.95 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr19_+_48606732 0.94 ENST00000321762.3
sperm acrosome associated 4
chr20_-_7940444 0.92 ENST00000378789.4
hydroxyacid oxidase 1
chr20_-_46684467 0.92 ENST00000372121.5
solute carrier family 13 member 3
chr5_+_141135199 0.89 ENST00000231134.8
ENST00000623915.1
protocadherin beta 5
chr4_-_185775484 0.88 ENST00000444771.5
sorbin and SH3 domain containing 2
chr7_+_66075876 0.87 ENST00000395332.8
argininosuccinate lyase
chr9_-_92482350 0.87 ENST00000375543.2
asporin
chr4_-_185775432 0.84 ENST00000457247.5
ENST00000435480.5
ENST00000425679.5
ENST00000457934.5
sorbin and SH3 domain containing 2
chr1_+_36084079 0.84 ENST00000207457.8
tektin 2
chr7_+_32979445 0.83 ENST00000418354.5
ENST00000490776.3
FKBP prolyl isomerase 9
chr4_-_185775411 0.79 ENST00000445115.5
ENST00000451701.5
sorbin and SH3 domain containing 2
chr8_-_28490220 0.78 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
F-box protein 16
chr4_-_185775376 0.62 ENST00000456596.5
ENST00000414724.5
sorbin and SH3 domain containing 2
chr6_+_52420107 0.60 ENST00000636489.1
ENST00000637089.1
ENST00000637353.1
ENST00000637263.1
EF-hand domain containing 1
chr12_+_18262730 0.60 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr6_+_151036912 0.57 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr12_-_39340963 0.55 ENST00000552961.5
kinesin family member 21A
chr4_+_107824555 0.54 ENST00000394684.8
sphingomyelin synthase 2
chr9_-_2844058 0.53 ENST00000397885.3
pumilio RNA binding family member 3
chr5_+_141430565 0.52 ENST00000613314.1
protocadherin gamma subfamily A, 12
chr3_+_130440510 0.51 ENST00000373157.8
collagen type VI alpha 5 chain
chr8_-_144605699 0.51 ENST00000377307.6
ENST00000276826.5
Rho GTPase activating protein 39
chr2_+_200440649 0.49 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr2_+_100821025 0.47 ENST00000427413.5
neuronal PAS domain protein 2
chr8_-_6926066 0.47 ENST00000297436.3
defensin alpha 6
chr17_+_42798881 0.45 ENST00000588527.5
cyclin N-terminal domain containing 1
chr1_+_54998927 0.44 ENST00000651561.1
barttin CLCNK type accessory subunit beta
chr6_-_87291988 0.41 ENST00000369576.2
gap junction protein beta 7
chr5_+_141430499 0.40 ENST00000252085.4
protocadherin gamma subfamily A, 12
chr3_-_185821092 0.39 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr5_+_102864505 0.37 ENST00000511839.5
peptidylglycine alpha-amidating monooxygenase
chr3_+_122680802 0.35 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr1_-_161367872 0.35 ENST00000367974.2
cilia and flagella associated protein 126
chrX_-_126166273 0.34 ENST00000360028.4
DDB1 and CUL4 associated factor 12 like 2
chr6_+_54308429 0.32 ENST00000259782.9
ENST00000370864.3
tubulointerstitial nephritis antigen
chr4_+_87650277 0.32 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr4_-_185761562 0.31 ENST00000445343.5
sorbin and SH3 domain containing 2
chr7_+_128709052 0.31 ENST00000485070.5
family with sequence similarity 71 member F1
chr9_-_13175824 0.29 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr16_-_58734299 0.28 ENST00000245206.10
ENST00000434819.2
glutamic-oxaloacetic transaminase 2
chr6_+_117482634 0.28 ENST00000296955.12
ENST00000338728.10
discoidin, CUB and LCCL domain containing 1
chr9_+_101185029 0.27 ENST00000395056.2
phospholipid phosphatase related 1
chr15_+_72118392 0.26 ENST00000340912.6
SUMO peptidase family member, NEDD8 specific
chr5_+_141182369 0.25 ENST00000609684.3
ENST00000625044.1
ENST00000623407.1
ENST00000623884.1
protocadherin beta 16
novel transcript
chr5_+_126423122 0.24 ENST00000515200.5
GRAM domain containing 2B
chr20_-_31722854 0.24 ENST00000307677.5
BCL2 like 1
chr14_+_67189393 0.23 ENST00000524532.5
ENST00000612183.4
ENST00000530728.5
family with sequence similarity 71 member D
chr16_+_56191476 0.23 ENST00000262493.12
G protein subunit alpha o1
chr9_-_5833014 0.22 ENST00000339450.10
endoplasmic reticulum metallopeptidase 1
chr14_+_20110739 0.20 ENST00000641386.2
ENST00000641633.2
olfactory receptor family 4 subfamily K member 17
chr4_+_68447453 0.20 ENST00000305363.9
transmembrane serine protease 11E
chr6_+_24356903 0.19 ENST00000274766.2
kidney associated antigen 1
chr6_-_135497230 0.19 ENST00000681365.1
Abelson helper integration site 1
chr8_-_92019156 0.19 ENST00000521054.5
RUNX1 partner transcriptional co-repressor 1
chr14_+_37795308 0.19 ENST00000267368.11
ENST00000382320.4
tetratricopeptide repeat domain 6
chr12_-_100262356 0.19 ENST00000548313.5
DEP domain containing 4
chr20_-_31722949 0.18 ENST00000376055.9
BCL2 like 1
chr11_-_14520429 0.18 ENST00000533068.5
proteasome 20S subunit alpha 1
chr2_-_61854013 0.17 ENST00000404929.6
FAM161 centrosomal protein A
chr11_-_63229652 0.17 ENST00000306494.10
solute carrier family 22 member 25
chrX_-_141698739 0.17 ENST00000370515.3
SPANX family member D
chrX_+_54807599 0.17 ENST00000375053.6
ENST00000627068.2
ENST00000375068.6
ENST00000347546.8
MAGE family member D2
chr2_-_61854119 0.17 ENST00000405894.3
FAM161 centrosomal protein A
chr4_-_993430 0.16 ENST00000361661.6
ENST00000622731.4
solute carrier family 26 member 1
chr9_-_104599413 0.16 ENST00000374779.3
olfactory receptor family 13 subfamily C member 5
chr4_-_185813121 0.15 ENST00000456060.5
sorbin and SH3 domain containing 2
chr21_+_30396030 0.15 ENST00000355459.4
keratin associated protein 13-1
chr6_+_132538290 0.14 ENST00000434551.2
trace amine associated receptor 9
chr6_-_160664270 0.14 ENST00000316300.10
lipoprotein(a)
chr1_+_51102221 0.13 ENST00000648827.1
ENST00000371759.7
chromosome 1 open reading frame 185
chr8_-_107497909 0.13 ENST00000517746.6
angiopoietin 1
chr8_-_107498041 0.12 ENST00000297450.7
angiopoietin 1
chr4_+_94489030 0.11 ENST00000510099.5
PDZ and LIM domain 5
chr18_-_13915531 0.10 ENST00000327606.4
melanocortin 2 receptor
chr1_+_51102238 0.10 ENST00000467127.5
chromosome 1 open reading frame 185
chr9_+_65700287 0.10 ENST00000489273.1
COBW domain containing 5
chr2_-_119366682 0.10 ENST00000409877.5
ENST00000409523.1
ENST00000409466.6
chromosome 2 open reading frame 76
chr19_+_7763210 0.10 ENST00000359059.10
ENST00000596363.5
ENST00000394122.7
ENST00000327325.10
C-type lectin domain family 4 member M
chr2_+_196713117 0.09 ENST00000409270.5
coiled-coil domain containing 150
chr1_-_153150884 0.09 ENST00000368748.5
small proline rich protein 2G
chr4_+_69280472 0.09 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr4_+_158315309 0.09 ENST00000460056.6
relaxin family peptide receptor 1
chr13_+_27919993 0.08 ENST00000381033.5
pancreatic and duodenal homeobox 1
chr1_-_686673 0.07 ENST00000332831.4
olfactory receptor family 4 subfamily F member 16
chr1_+_170145959 0.07 ENST00000439373.3
methyltransferase like 11B
chr3_+_51817596 0.07 ENST00000456080.5
novel protein
chr19_-_14848922 0.07 ENST00000641129.1
olfactory receptor family 7 subfamily A member 10
chr14_+_94026314 0.07 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr1_+_51617079 0.06 ENST00000447887.5
ENST00000428468.6
ENST00000453295.5
oxysterol binding protein like 9
chr12_-_16600703 0.06 ENST00000616247.4
LIM domain only 3
chr6_+_29457155 0.06 ENST00000377133.6
ENST00000377136.5
olfactory receptor family 2 subfamily H member 1
chr3_+_130850585 0.06 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr4_+_70592253 0.06 ENST00000322937.10
ENST00000613447.4
ameloblastin
chr4_-_993376 0.05 ENST00000398520.6
ENST00000398516.3
solute carrier family 26 member 1
chr4_+_113145608 0.05 ENST00000511380.1
ankyrin 2
chr18_-_23437927 0.05 ENST00000578520.5
ENST00000383233.8
transmembrane protein 241
chr3_+_128051610 0.04 ENST00000464451.5
SEC61 translocon subunit alpha 1
chr20_-_31722533 0.04 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2 like 1
chr10_-_84225537 0.03 ENST00000372113.7
ENST00000538192.5
leucine rich repeat, Ig-like and transmembrane domains 2
chr3_+_141262614 0.03 ENST00000504264.5
2-phosphoxylose phosphatase 1
chrX_+_11293411 0.02 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
amelogenin X-linked
chr4_+_26576670 0.02 ENST00000512840.5
TBC1 domain family member 19
chr1_-_13285154 0.01 ENST00000357367.6
ENST00000614831.1
PRAME family member 8
chr14_+_63761836 0.01 ENST00000674003.1
spectrin repeat containing nuclear envelope protein 2
chr15_-_33119365 0.01 ENST00000672206.1
formin 1
chr1_+_95151377 0.01 ENST00000604203.1
TLCD4-RWDD3 readthrough
chr5_+_171785817 0.01 ENST00000523047.4
ENST00000330910.7
small integral membrane protein 23
chr15_-_72118114 0.00 ENST00000356056.10
ENST00000569314.1
myosin IXA

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.8 2.5 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.8 3.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.5 2.4 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.5 3.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 5.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 1.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 0.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 1.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 1.9 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.9 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.2 4.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 3.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 0.9 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.2 1.9 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2 1.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 2.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 7.1 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.6 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 3.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.4 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.2 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.5 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 2.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0010260 organ senescence(GO:0010260)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.0 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.6 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.1 GO:0005577 fibrinogen complex(GO:0005577)
0.5 3.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.3 2.6 GO:0044305 calyx of Held(GO:0044305)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 5.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 5.2 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 6.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.8 3.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.5 2.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 0.9 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.3 0.9 GO:0004056 argininosuccinate lyase activity(GO:0004056)
0.2 0.9 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.2 1.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 5.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 6.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 3.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 2.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.9 GO:0003796 lysozyme activity(GO:0003796)
0.0 8.1 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 4.1 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 8.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA