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Illumina Body Map 2 (GSE30611)

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Results for BBX

Z-value: 0.89

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Transcription factors associated with BBX

Gene Symbol Gene ID Gene Info
BBX
ENSG00000114439.19 BBX high mobility group box domain containing

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BBXhg38_v1_chr3_+_107524357_1075243760.115.5e-01Click!

Activity profile of BBX motif

Sorted Z-values of BBX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_154563003 5.60 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr7_-_16881967 3.47 ENST00000402239.7
ENST00000310398.7
ENST00000414935.1
AGR3
anterior gradient 3, protein disulphide isomerase family member
chr16_+_56638659 3.18 ENST00000290705.12
MT1A
metallothionein 1A
chr11_+_60699605 3.18 ENST00000300226.7
MS4A8
membrane spanning 4-domains A8
chr2_-_215393126 2.53 ENST00000456923.5
FN1
fibronectin 1
chr9_-_92404559 2.49 ENST00000262551.8
ENST00000375561.10
OGN
osteoglycin
chr7_-_16833411 2.41 ENST00000412973.1
AGR2
anterior gradient 2, protein disulphide isomerase family member
chr11_+_60699669 2.27 ENST00000529752.5
MS4A8
membrane spanning 4-domains A8
chr3_-_58666765 2.27 ENST00000358781.7
FAM3D
FAM3 metabolism regulating signaling molecule D
chr2_+_102311546 2.20 ENST00000233954.6
ENST00000447231.5
IL1RL1
interleukin 1 receptor like 1
chr9_-_92404690 2.06 ENST00000447356.1
OGN
osteoglycin
chr3_+_151814102 1.98 ENST00000232892.12
AADAC
arylacetamide deacetylase
chr1_-_58577244 1.91 ENST00000371225.4
TACSTD2
tumor associated calcium signal transducer 2
chr7_+_117480052 1.65 ENST00000426809.5
ENST00000649781.1
CFTR
CF transmembrane conductance regulator
chr2_+_102311502 1.63 ENST00000404917.6
ENST00000410040.5
IL1RL1
IL18R1
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr6_-_25874212 1.56 ENST00000361703.10
ENST00000397060.8
SLC17A3
solute carrier family 17 member 3
chr7_+_117480011 1.52 ENST00000649406.1
ENST00000648260.1
ENST00000003084.11
CFTR
CF transmembrane conductance regulator
chr9_+_35161951 1.51 ENST00000617908.4
ENST00000619578.4
UNC13B
unc-13 homolog B
chr3_+_148865288 1.35 ENST00000296046.4
CPA3
carboxypeptidase A3
chr6_+_31927486 1.33 ENST00000442278.6
C2
complement C2
chr3_-_169147734 1.30 ENST00000464456.5
MECOM
MDS1 and EVI1 complex locus
chr4_-_185775271 1.29 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
SORBS2
sorbin and SH3 domain containing 2
chr6_-_49744434 1.25 ENST00000433368.6
ENST00000354620.4
CRISP3
cysteine rich secretory protein 3
chr6_+_121437378 1.19 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr6_-_49744378 1.18 ENST00000371159.8
ENST00000263045.9
CRISP3
cysteine rich secretory protein 3
chr4_-_103099811 1.14 ENST00000504285.5
ENST00000296424.9
BDH2
3-hydroxybutyrate dehydrogenase 2
chr3_+_151814069 1.13 ENST00000488869.1
AADAC
arylacetamide deacetylase
chr4_-_185775890 1.11 ENST00000437304.6
SORBS2
sorbin and SH3 domain containing 2
chr3_-_146528750 1.07 ENST00000483300.5
PLSCR1
phospholipid scramblase 1
chr9_+_35162000 1.06 ENST00000396787.5
ENST00000378495.7
ENST00000635942.1
ENST00000378496.8
UNC13B
unc-13 homolog B
chr15_+_49423233 1.05 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
FGF7
fibroblast growth factor 7
chr15_+_40351026 0.99 ENST00000448599.2
PHGR1
proline, histidine and glycine rich 1
chr4_-_103099852 0.99 ENST00000509245.1
BDH2
3-hydroxybutyrate dehydrogenase 2
chr9_-_92482499 0.99 ENST00000375544.7
ASPN
asporin
chr6_+_31927510 0.97 ENST00000447952.6
C2
complement C2
chr1_+_192575765 0.95 ENST00000469578.2
ENST00000367459.8
RGS1
regulator of G protein signaling 1
chr4_-_185812209 0.95 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
SORBS2
sorbin and SH3 domain containing 2
chr19_+_48606732 0.94 ENST00000321762.3
SPACA4
sperm acrosome associated 4
chr20_-_7940444 0.92 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr20_-_46684467 0.92 ENST00000372121.5
SLC13A3
solute carrier family 13 member 3
chr5_+_141135199 0.89 ENST00000231134.8
ENST00000623915.1
PCDHB5
protocadherin beta 5
chr4_-_185775484 0.88 ENST00000444771.5
SORBS2
sorbin and SH3 domain containing 2
chr7_+_66075876 0.87 ENST00000395332.8
ASL
argininosuccinate lyase
chr9_-_92482350 0.87 ENST00000375543.2
ASPN
asporin
chr4_-_185775432 0.84 ENST00000457247.5
ENST00000435480.5
ENST00000425679.5
ENST00000457934.5
SORBS2
sorbin and SH3 domain containing 2
chr1_+_36084079 0.84 ENST00000207457.8
TEKT2
tektin 2
chr7_+_32979445 0.83 ENST00000418354.5
ENST00000490776.3
FKBP9
FKBP prolyl isomerase 9
chr4_-_185775411 0.79 ENST00000445115.5
ENST00000451701.5
SORBS2
sorbin and SH3 domain containing 2
chr8_-_28490220 0.78 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
FBXO16
F-box protein 16
chr4_-_185775376 0.62 ENST00000456596.5
ENST00000414724.5
SORBS2
sorbin and SH3 domain containing 2
chr6_+_52420107 0.60 ENST00000636489.1
ENST00000637089.1
ENST00000637353.1
ENST00000637263.1
EFHC1
EF-hand domain containing 1
chr12_+_18262730 0.60 ENST00000675017.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr6_+_151036912 0.57 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr12_-_39340963 0.55 ENST00000552961.5
KIF21A
kinesin family member 21A
chr4_+_107824555 0.54 ENST00000394684.8
SGMS2
sphingomyelin synthase 2
chr9_-_2844058 0.53 ENST00000397885.3
PUM3
pumilio RNA binding family member 3
chr5_+_141430565 0.52 ENST00000613314.1
PCDHGA12
protocadherin gamma subfamily A, 12
chr3_+_130440510 0.51 ENST00000373157.8
COL6A5
collagen type VI alpha 5 chain
chr8_-_144605699 0.51 ENST00000377307.6
ENST00000276826.5
ARHGAP39
Rho GTPase activating protein 39
chr2_+_200440649 0.49 ENST00000366118.2
SPATS2L
spermatogenesis associated serine rich 2 like
chr2_+_100821025 0.47 ENST00000427413.5
NPAS2
neuronal PAS domain protein 2
chr8_-_6926066 0.47 ENST00000297436.3
DEFA6
defensin alpha 6
chr17_+_42798881 0.45 ENST00000588527.5
CNTD1
cyclin N-terminal domain containing 1
chr1_+_54998927 0.44 ENST00000651561.1
BSND
barttin CLCNK type accessory subunit beta
chr6_-_87291988 0.41 ENST00000369576.2
GJB7
gap junction protein beta 7
chr5_+_141430499 0.40 ENST00000252085.4
PCDHGA12
protocadherin gamma subfamily A, 12
chr3_-_185821092 0.39 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr5_+_102864505 0.37 ENST00000511839.5
PAM
peptidylglycine alpha-amidating monooxygenase
chr3_+_122680802 0.35 ENST00000474629.7
PARP14
poly(ADP-ribose) polymerase family member 14
chr1_-_161367872 0.35 ENST00000367974.2
CFAP126
cilia and flagella associated protein 126
chrX_-_126166273 0.34 ENST00000360028.4
DCAF12L2
DDB1 and CUL4 associated factor 12 like 2
chr6_+_54308429 0.32 ENST00000259782.9
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr4_+_87650277 0.32 ENST00000339673.11
ENST00000282479.8
DMP1
dentin matrix acidic phosphoprotein 1
chr4_-_185761562 0.31 ENST00000445343.5
SORBS2
sorbin and SH3 domain containing 2
chr7_+_128709052 0.31 ENST00000485070.5
FAM71F1
family with sequence similarity 71 member F1
chr9_-_13175824 0.29 ENST00000545857.5
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr16_-_58734299 0.28 ENST00000245206.10
ENST00000434819.2
GOT2
glutamic-oxaloacetic transaminase 2
chr6_+_117482634 0.28 ENST00000296955.12
ENST00000338728.10
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr9_+_101185029 0.27 ENST00000395056.2
PLPPR1
phospholipid phosphatase related 1
chr15_+_72118392 0.26 ENST00000340912.6
SENP8
SUMO peptidase family member, NEDD8 specific
chr5_+_141182369 0.25 ENST00000609684.3
ENST00000625044.1
ENST00000623407.1
ENST00000623884.1
PCDHB16
ENSG00000279068.1
protocadherin beta 16
novel transcript
chr5_+_126423122 0.24 ENST00000515200.5
GRAMD2B
GRAM domain containing 2B
chr20_-_31722854 0.24 ENST00000307677.5
BCL2L1
BCL2 like 1
chr14_+_67189393 0.23 ENST00000524532.5
ENST00000612183.4
ENST00000530728.5
FAM71D
family with sequence similarity 71 member D
chr16_+_56191476 0.23 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr9_-_5833014 0.22 ENST00000339450.10
ERMP1
endoplasmic reticulum metallopeptidase 1
chr14_+_20110739 0.20 ENST00000641386.2
ENST00000641633.2
OR4K17
olfactory receptor family 4 subfamily K member 17
chr4_+_68447453 0.20 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr6_+_24356903 0.19 ENST00000274766.2
KAAG1
kidney associated antigen 1
chr6_-_135497230 0.19 ENST00000681365.1
AHI1
Abelson helper integration site 1
chr8_-_92019156 0.19 ENST00000521054.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr14_+_37795308 0.19 ENST00000267368.11
ENST00000382320.4
TTC6
tetratricopeptide repeat domain 6
chr12_-_100262356 0.19 ENST00000548313.5
DEPDC4
DEP domain containing 4
chr20_-_31722949 0.18 ENST00000376055.9
BCL2L1
BCL2 like 1
chr11_-_14520429 0.18 ENST00000533068.5
PSMA1
proteasome 20S subunit alpha 1
chr2_-_61854013 0.17 ENST00000404929.6
FAM161A
FAM161 centrosomal protein A
chr11_-_63229652 0.17 ENST00000306494.10
SLC22A25
solute carrier family 22 member 25
chrX_-_141698739 0.17 ENST00000370515.3
SPANXD
SPANX family member D
chrX_+_54807599 0.17 ENST00000375053.6
ENST00000627068.2
ENST00000375068.6
ENST00000347546.8
MAGED2
MAGE family member D2
chr2_-_61854119 0.17 ENST00000405894.3
FAM161A
FAM161 centrosomal protein A
chr4_-_993430 0.16 ENST00000361661.6
ENST00000622731.4
SLC26A1
solute carrier family 26 member 1
chr9_-_104599413 0.16 ENST00000374779.3
OR13C5
olfactory receptor family 13 subfamily C member 5
chr4_-_185813121 0.15 ENST00000456060.5
SORBS2
sorbin and SH3 domain containing 2
chr21_+_30396030 0.15 ENST00000355459.4
KRTAP13-1
keratin associated protein 13-1
chr6_+_132538290 0.14 ENST00000434551.2
TAAR9
trace amine associated receptor 9
chr6_-_160664270 0.14 ENST00000316300.10
LPA
lipoprotein(a)
chr1_+_51102221 0.13 ENST00000648827.1
ENST00000371759.7
C1orf185
chromosome 1 open reading frame 185
chr8_-_107497909 0.13 ENST00000517746.6
ANGPT1
angiopoietin 1
chr8_-_107498041 0.12 ENST00000297450.7
ANGPT1
angiopoietin 1
chr4_+_94489030 0.11 ENST00000510099.5
PDLIM5
PDZ and LIM domain 5
chr18_-_13915531 0.10 ENST00000327606.4
MC2R
melanocortin 2 receptor
chr1_+_51102238 0.10 ENST00000467127.5
C1orf185
chromosome 1 open reading frame 185
chr9_+_65700287 0.10 ENST00000489273.1
CBWD5
COBW domain containing 5
chr2_-_119366682 0.10 ENST00000409877.5
ENST00000409523.1
ENST00000409466.6
C2orf76
chromosome 2 open reading frame 76
chr19_+_7763210 0.10 ENST00000359059.10
ENST00000596363.5
ENST00000394122.7
ENST00000327325.10
CLEC4M
C-type lectin domain family 4 member M
chr2_+_196713117 0.09 ENST00000409270.5
CCDC150
coiled-coil domain containing 150
chr1_-_153150884 0.09 ENST00000368748.5
SPRR2G
small proline rich protein 2G
chr4_+_69280472 0.09 ENST00000335568.10
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase family 2 member B28
chr4_+_158315309 0.09 ENST00000460056.6
RXFP1
relaxin family peptide receptor 1
chr13_+_27919993 0.08 ENST00000381033.5
PDX1
pancreatic and duodenal homeobox 1
chr1_-_686673 0.07 ENST00000332831.4
OR4F16
olfactory receptor family 4 subfamily F member 16
chr1_+_170145959 0.07 ENST00000439373.3
METTL11B
methyltransferase like 11B
chr3_+_51817596 0.07 ENST00000456080.5
ENSG00000285749.2
novel protein
chr19_-_14848922 0.07 ENST00000641129.1
OR7A10
olfactory receptor family 7 subfamily A member 10
chr14_+_94026314 0.07 ENST00000203664.10
ENST00000553723.1
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr1_+_51617079 0.06 ENST00000447887.5
ENST00000428468.6
ENST00000453295.5
OSBPL9
oxysterol binding protein like 9
chr12_-_16600703 0.06 ENST00000616247.4
LMO3
LIM domain only 3
chr6_+_29457155 0.06 ENST00000377133.6
ENST00000377136.5
OR2H1
olfactory receptor family 2 subfamily H member 1
chr3_+_130850585 0.06 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr4_+_70592253 0.06 ENST00000322937.10
ENST00000613447.4
AMBN
ameloblastin
chr4_-_993376 0.05 ENST00000398520.6
ENST00000398516.3
SLC26A1
solute carrier family 26 member 1
chr4_+_113145608 0.05 ENST00000511380.1
ANK2
ankyrin 2
chr18_-_23437927 0.05 ENST00000578520.5
ENST00000383233.8
TMEM241
transmembrane protein 241
chr3_+_128051610 0.04 ENST00000464451.5
SEC61A1
SEC61 translocon subunit alpha 1
chr20_-_31722533 0.04 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2L1
BCL2 like 1
chr10_-_84225537 0.03 ENST00000372113.7
ENST00000538192.5
LRIT2
leucine rich repeat, Ig-like and transmembrane domains 2
chr3_+_141262614 0.03 ENST00000504264.5
PXYLP1
2-phosphoxylose phosphatase 1
chrX_+_11293411 0.02 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
AMELX
amelogenin X-linked
chr4_+_26576670 0.02 ENST00000512840.5
TBC1D19
TBC1 domain family member 19
chr1_-_13285154 0.01 ENST00000357367.6
ENST00000614831.1
PRAMEF8
PRAME family member 8
chr14_+_63761836 0.01 ENST00000674003.1
SYNE2
spectrin repeat containing nuclear envelope protein 2
chr15_-_33119365 0.01 ENST00000672206.1
FMN1
formin 1
chr1_+_95151377 0.01 ENST00000604203.1
TLCD4-RWDD3
TLCD4-RWDD3 readthrough
chr5_+_171785817 0.01 ENST00000523047.4
ENST00000330910.7
SMIM23
small integral membrane protein 23
chr15_-_72118114 0.00 ENST00000356056.10
ENST00000569314.1
MYO9A
myosin IXA

Network of associatons between targets according to the STRING database.

First level regulatory network of BBX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.8 2.5 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.8 3.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.5 2.4 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.5 3.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 5.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 1.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 0.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 1.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 1.9 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.9 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.2 4.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 3.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 0.9 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.2 1.9 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2 1.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 2.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 7.1 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.6 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 3.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.4 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.2 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.5 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 2.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0010260 organ senescence(GO:0010260)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.0 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.6 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.1 GO:0005577 fibrinogen complex(GO:0005577)
0.5 3.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.3 2.6 GO:0044305 calyx of Held(GO:0044305)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 5.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 5.2 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 6.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.8 3.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.5 2.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 0.9 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.3 0.9 GO:0004056 argininosuccinate lyase activity(GO:0004056)
0.2 0.9 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.2 1.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 5.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 6.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 3.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 2.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.9 GO:0003796 lysozyme activity(GO:0003796)
0.0 8.1 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 4.1 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 8.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA