Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 0.87

Motif logo

logo of logo of logo of

Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
BHLHE22
ENSG00000180828.3 basic helix-loop-helix family member e22
BHLHA15
ENSG00000180535.4 basic helix-loop-helix family member a15
BHLHE23
ENSG00000125533.6 basic helix-loop-helix family member e23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHA15hg38_v1_chr7_+_98211431_982114740.476.3e-03Click!
BHLHE23hg38_v1_chr20_-_63006961_630070350.076.9e-01Click!
BHLHE22hg38_v1_chr8_+_64580357_645803740.038.7e-01Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_157439403 7.61 ENST00000418920.5
CYTIP
cytohesin 1 interacting protein
chrX_+_129779930 6.59 ENST00000356892.4
SASH3
SAM and SH3 domain containing 3
chr19_-_11339573 4.83 ENST00000222120.8
RAB3D
RAB3D, member RAS oncogene family
chr7_-_27165517 4.67 ENST00000396345.1
ENST00000343483.7
HOXA9
homeobox A9
chr2_-_181680490 4.66 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
CERKL
NEUROD1
ceramide kinase like
neuronal differentiation 1
chr11_+_65638085 4.25 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chr8_-_100712761 3.79 ENST00000517403.5
PABPC1
poly(A) binding protein cytoplasmic 1
chr6_+_135181361 3.06 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB
MYB proto-oncogene, transcription factor
chr3_-_121660892 3.01 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_-_27165457 2.73 ENST00000673744.1
ENST00000673917.1
HOXA9
homeobox A9
chr5_-_170297746 2.46 ENST00000046794.10
LCP2
lymphocyte cytosolic protein 2
chr12_-_14938508 2.43 ENST00000266397.7
ERP27
endoplasmic reticulum protein 27
chr19_-_54364983 2.29 ENST00000434277.6
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr14_+_22207502 2.19 ENST00000390461.2
TRAV34
T cell receptor alpha variable 34
chrX_-_19799751 2.05 ENST00000379698.8
SH3KBP1
SH3 domain containing kinase binding protein 1
chr14_-_68978240 1.91 ENST00000556571.1
ENST00000553659.1
ENST00000555616.5
ACTN1
actinin alpha 1
chr1_+_244051275 1.87 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chrX_+_108045050 1.73 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr14_-_106025628 1.71 ENST00000631943.1
IGHV7-4-1
immunoglobulin heavy variable 7-4-1
chr7_+_114922854 1.66 ENST00000423503.1
ENST00000427207.5
MDFIC
MyoD family inhibitor domain containing
chr12_+_64610458 1.64 ENST00000542104.6
RASSF3
Ras association domain family member 3
chr2_-_32265732 1.58 ENST00000360906.9
ENST00000342905.10
NLRC4
NLR family CARD domain containing 4
chr12_+_64610511 1.58 ENST00000336061.2
RASSF3
Ras association domain family member 3
chr5_+_157180816 1.55 ENST00000422843.8
ITK
IL2 inducible T cell kinase
chrX_+_108044967 1.48 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr16_-_69351778 1.47 ENST00000288025.4
TMED6
transmembrane p24 trafficking protein 6
chr1_+_159302321 1.45 ENST00000368114.1
FCER1A
Fc fragment of IgE receptor Ia
chr1_+_100345018 1.45 ENST00000635056.2
ENST00000647005.1
CDC14A
cell division cycle 14A
chr3_+_113532508 1.28 ENST00000264852.9
SIDT1
SID1 transmembrane family member 1
chr9_+_18474100 1.27 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTSL1
ADAMTS like 1
chr8_-_38382146 1.27 ENST00000534155.1
ENST00000433384.6
ENST00000317025.13
ENST00000316985.7
NSD3
nuclear receptor binding SET domain protein 3
chr6_-_111793871 1.03 ENST00000368667.6
FYN
FYN proto-oncogene, Src family tyrosine kinase
chr17_-_49209367 1.02 ENST00000300406.6
ENST00000511277.5
ENST00000511673.1
GNGT2
G protein subunit gamma transducin 2
chr19_+_18097763 0.91 ENST00000262811.10
MAST3
microtubule associated serine/threonine kinase 3
chr4_-_140154176 0.90 ENST00000509479.6
MAML3
mastermind like transcriptional coactivator 3
chr4_-_158173004 0.88 ENST00000585682.6
GASK1B
golgi associated kinase 1B
chr6_-_111793900 0.83 ENST00000462598.7
FYN
FYN proto-oncogene, Src family tyrosine kinase
chr5_+_138338256 0.82 ENST00000513056.5
ENST00000239906.10
ENST00000511276.1
FAM53C
family with sequence similarity 53 member C
chr3_-_179266971 0.82 ENST00000349697.2
ENST00000497599.5
KCNMB3
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr12_-_39619782 0.75 ENST00000308666.4
ABCD2
ATP binding cassette subfamily D member 2
chr15_-_55408018 0.73 ENST00000569205.5
CCPG1
cell cycle progression 1
chr4_-_158173042 0.71 ENST00000592057.1
ENST00000393807.9
GASK1B
golgi associated kinase 1B
chr9_-_73865 0.70 ENST00000642633.1
WASHC1
WASH complex subunit 1
chr1_+_50103903 0.70 ENST00000371827.5
ELAVL4
ELAV like RNA binding protein 4
chr5_-_111976925 0.67 ENST00000395634.7
NREP
neuronal regeneration related protein
chr7_-_24918080 0.67 ENST00000441059.5
ENST00000415162.5
OSBPL3
oxysterol binding protein like 3
chr17_+_41689862 0.65 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr6_-_65707214 0.64 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
EYS
eyes shut homolog
chr5_-_138338325 0.63 ENST00000510119.1
ENST00000513970.5
CDC25C
cell division cycle 25C
chr18_-_5521373 0.62 ENST00000580989.5
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr9_+_18474165 0.61 ENST00000380566.8
ADAMTSL1
ADAMTS like 1
chr2_-_181680636 0.58 ENST00000479558.5
CERKL
ceramide kinase like
chr12_-_108320635 0.57 ENST00000412676.5
ENST00000550573.5
CMKLR1
chemerin chemokine-like receptor 1
chr14_-_50831046 0.54 ENST00000476352.5
ENST00000324330.13
ENST00000382041.7
ENST00000453401.6
ENST00000530997.7
NIN
ninein
chr2_+_218245426 0.54 ENST00000456575.1
ARPC2
actin related protein 2/3 complex subunit 2
chr11_+_124566660 0.54 ENST00000641670.1
OR8A1
olfactory receptor family 8 subfamily A member 1
chr17_-_181640 0.53 ENST00000613549.3
DOC2B
double C2 domain beta
chr10_+_5094405 0.53 ENST00000380554.5
AKR1C3
aldo-keto reductase family 1 member C3
chr5_-_115296610 0.53 ENST00000379611.10
ENST00000506442.5
CCDC112
coiled-coil domain containing 112
chr4_-_112285892 0.51 ENST00000361717.4
TIFA
TRAF interacting protein with forkhead associated domain
chr17_-_75878542 0.49 ENST00000254816.6
TRIM47
tripartite motif containing 47
chr18_+_13277351 0.48 ENST00000679091.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr15_+_67067780 0.48 ENST00000679624.1
SMAD3
SMAD family member 3
chr11_-_44950867 0.48 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
TP53I11
tumor protein p53 inducible protein 11
chr11_+_18602969 0.47 ENST00000636011.1
ENST00000542172.1
SPTY2D1OS
SPTY2D1 opposite strand
chr17_-_39607876 0.47 ENST00000302584.5
NEUROD2
neuronal differentiation 2
chr1_-_152159227 0.45 ENST00000316073.3
RPTN
repetin
chr3_+_46883337 0.44 ENST00000313049.9
PTH1R
parathyroid hormone 1 receptor
chr14_-_106875069 0.44 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr5_-_115296261 0.44 ENST00000395557.4
CCDC112
coiled-coil domain containing 112
chr4_+_159267737 0.44 ENST00000264431.8
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr17_+_77320252 0.42 ENST00000591934.1
SEPTIN9
septin 9
chr3_-_108953870 0.42 ENST00000261047.8
GUCA1C
guanylate cyclase activator 1C
chr2_-_144516154 0.40 ENST00000637304.1
ZEB2
zinc finger E-box binding homeobox 2
chr14_-_50830479 0.39 ENST00000382043.8
NIN
ninein
chr5_-_59430600 0.39 ENST00000636120.1
PDE4D
phosphodiesterase 4D
chr14_-_50830641 0.39 ENST00000453196.6
ENST00000496749.1
NIN
ninein
chr8_-_23457618 0.36 ENST00000358689.9
ENST00000518718.1
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr17_-_49208882 0.36 ENST00000503070.5
GNGT2
G protein subunit gamma transducin 2
chr15_-_55408245 0.35 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
CCPG1
cell cycle progression 1
chr5_+_180909564 0.35 ENST00000505126.5
ENST00000533815.2
BTNL8
butyrophilin like 8
chr7_-_93226449 0.35 ENST00000394468.7
ENST00000453812.2
HEPACAM2
HEPACAM family member 2
chr7_-_55862750 0.34 ENST00000388975.4
SEPTIN14
septin 14
chrX_+_106611930 0.34 ENST00000372544.6
ENST00000372548.9
RADX
RPA1 related single stranded DNA binding protein, X-linked
chr8_+_21966215 0.33 ENST00000433566.8
XPO7
exportin 7
chr17_+_7308339 0.33 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr3_-_53130405 0.32 ENST00000467048.1
ENST00000296292.8
ENST00000394738.7
RFT1
RFT1 homolog
chr7_-_98252117 0.32 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
TECPR1
tectonin beta-propeller repeat containing 1
chr8_-_23457677 0.31 ENST00000356206.10
ENST00000417069.6
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr12_+_57772587 0.30 ENST00000300209.13
EEF1AKMT3
EEF1A lysine methyltransferase 3
chr3_+_113211525 0.30 ENST00000498710.1
BOC
BOC cell adhesion associated, oncogene regulated
chr3_-_108953762 0.30 ENST00000393963.7
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr3_-_52685531 0.29 ENST00000439181.5
ENST00000449505.5
PBRM1
polybromo 1
chr3_-_50350710 0.29 ENST00000232501.8
NPRL2
NPR2 like, GATOR1 complex subunit
chr1_-_205121986 0.28 ENST00000367164.1
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit
chr4_+_68447453 0.27 ENST00000305363.9
TMPRSS11E
transmembrane serine protease 11E
chr4_-_107283746 0.27 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr11_+_66241227 0.26 ENST00000531597.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr12_+_57772648 0.26 ENST00000333012.5
EEF1AKMT3
EEF1A lysine methyltransferase 3
chr14_-_52695652 0.26 ENST00000629528.2
ERO1A
endoplasmic reticulum oxidoreductase 1 alpha
chr8_-_134510182 0.24 ENST00000521673.5
ZFAT
zinc finger and AT-hook domain containing
chr10_+_17752185 0.24 ENST00000377495.2
TMEM236
transmembrane protein 236
chr4_+_2812259 0.23 ENST00000502260.5
ENST00000435136.8
SH3BP2
SH3 domain binding protein 2
chr1_+_20290869 0.23 ENST00000289815.13
ENST00000375079.6
VWA5B1
von Willebrand factor A domain containing 5B1
chr7_+_116862552 0.23 ENST00000361183.8
ENST00000639546.1
ENST00000490693.5
CAPZA2
capping actin protein of muscle Z-line subunit alpha 2
chr4_-_73223082 0.22 ENST00000509867.6
ANKRD17
ankyrin repeat domain 17
chr1_+_180928427 0.20 ENST00000483705.6
KIAA1614
KIAA1614
chr12_+_50401108 0.20 ENST00000517559.5
ENST00000552445.1
LARP4
La ribonucleoprotein 4
chr1_+_103750406 0.19 ENST00000370079.3
AMY1C
amylase alpha 1C
chr10_-_72354895 0.19 ENST00000444643.8
ENST00000338820.7
ENST00000394903.6
DNAJB12
DnaJ heat shock protein family (Hsp40) member B12
chr3_-_18438767 0.19 ENST00000454909.6
SATB1
SATB homeobox 1
chr3_+_137998735 0.19 ENST00000343735.8
CLDN18
claudin 18
chr1_+_110339323 0.18 ENST00000602849.1
ENST00000487146.8
ENST00000618772.4
ENST00000369784.9
ENST00000650953.2
ENST00000652342.2
ENST00000654015.1
RBM15
RNA binding motif protein 15
chr16_+_21704963 0.17 ENST00000388957.3
OTOA
otoancorin
chr3_+_62318983 0.17 ENST00000232519.9
ENST00000462069.6
ENST00000465142.5
C3orf14
chromosome 3 open reading frame 14
chr16_-_4846196 0.16 ENST00000589389.5
GLYR1
glyoxylate reductase 1 homolog
chr17_-_676348 0.16 ENST00000681510.1
ENST00000679680.1
VPS53
VPS53 subunit of GARP complex
chr18_-_25224689 0.15 ENST00000577775.1
ZNF521
zinc finger protein 521
chr7_+_50095841 0.15 ENST00000297001.7
SPATA48
spermatogenesis associated 48
chr15_+_57219411 0.15 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
TCF12
transcription factor 12
chr7_-_48029102 0.14 ENST00000297325.9
ENST00000412142.5
ENST00000395572.6
SUN3
Sad1 and UNC84 domain containing 3
chr3_+_172040554 0.14 ENST00000336824.8
ENST00000423424.5
FNDC3B
fibronectin type III domain containing 3B
chr11_-_26722051 0.14 ENST00000396005.8
SLC5A12
solute carrier family 5 member 12
chr11_-_26721999 0.13 ENST00000280467.10
SLC5A12
solute carrier family 5 member 12
chr3_+_113211459 0.13 ENST00000495514.5
BOC
BOC cell adhesion associated, oncogene regulated
chr10_-_46030585 0.13 ENST00000580070.5
ENST00000578454.5
ENST00000585056.5
ENST00000579039.2
ENST00000581486.6
NCOA4
nuclear receptor coactivator 4
chr17_+_7307961 0.12 ENST00000419711.6
ENST00000571955.5
ENST00000573714.5
EIF5A
eukaryotic translation initiation factor 5A
chr3_-_18438678 0.12 ENST00000414509.5
SATB1
SATB homeobox 1
chr12_-_30735014 0.12 ENST00000433722.6
CAPRIN2
caprin family member 2
chr8_-_16567362 0.11 ENST00000518026.5
MSR1
macrophage scavenger receptor 1
chr12_-_102478539 0.11 ENST00000424202.6
IGF1
insulin like growth factor 1
chr15_+_84600986 0.11 ENST00000540936.1
ENST00000448803.6
ENST00000546275.1
ENST00000546148.6
ENST00000442073.3
ENST00000334141.7
ENST00000358472.3
ENST00000502939.2
ENST00000379358.7
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chrX_-_130268883 0.10 ENST00000447817.1
ENST00000370978.9
ZNF280C
zinc finger protein 280C
chr6_-_116829037 0.10 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
GPRC6A
G protein-coupled receptor class C group 6 member A
chr4_+_54229261 0.09 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
PDGFRA
platelet derived growth factor receptor alpha
chr9_+_12775012 0.09 ENST00000319264.4
LURAP1L
leucine rich adaptor protein 1 like
chr7_-_41703062 0.09 ENST00000242208.5
INHBA
inhibin subunit beta A
chr3_-_33659441 0.09 ENST00000650653.1
ENST00000480013.6
CLASP2
cytoplasmic linker associated protein 2
chr11_+_22672577 0.08 ENST00000534801.5
GAS2
growth arrest specific 2
chr3_+_113211539 0.08 ENST00000682979.1
ENST00000485230.5
BOC
BOC cell adhesion associated, oncogene regulated
chr1_+_110339462 0.08 ENST00000617047.1
RBM15
RNA binding motif protein 15
chr17_-_58415628 0.08 ENST00000583753.5
RNF43
ring finger protein 43
chrX_+_108091665 0.07 ENST00000345734.7
ATG4A
autophagy related 4A cysteine peptidase
chr1_+_180928133 0.07 ENST00000367587.1
KIAA1614
KIAA1614
chr15_-_63156774 0.07 ENST00000462430.5
RPS27L
ribosomal protein S27 like
chr6_+_31919984 0.06 ENST00000413154.5
C2
complement C2
chrX_+_108091752 0.06 ENST00000457035.5
ENST00000372232.8
ATG4A
autophagy related 4A cysteine peptidase
chr16_+_72108296 0.04 ENST00000563819.5
ENST00000567142.2
DHX38
DEAH-box helicase 38
chr11_-_8774241 0.04 ENST00000528196.5
ENST00000533681.5
DENND2B
DENN domain containing 2B
chr14_-_76826229 0.03 ENST00000557497.1
ANGEL1
angel homolog 1
chr14_+_69398683 0.02 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
SLC39A9
solute carrier family 39 member 9
chrX_+_70290077 0.02 ENST00000374403.4
KIF4A
kinesin family member 4A
chr11_-_89063631 0.02 ENST00000455756.6
GRM5
glutamate metabotropic receptor 5
chr3_-_33659097 0.02 ENST00000461133.8
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr17_-_9822071 0.01 ENST00000399363.4
GSG1L2
GSG1 like 2
chr17_+_82900542 0.01 ENST00000574422.1
TBCD
tubulin folding cofactor D
chr9_+_2158487 0.01 ENST00000634706.1
ENST00000634338.1
ENST00000635688.1
ENST00000634435.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_-_113118544 0.00 ENST00000397764.8
ENST00000441359.1
SMIM30
small integral membrane protein 30

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
1.2 4.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
1.1 4.2 GO:0042631 cellular response to water deprivation(GO:0042631)
1.0 3.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.5 1.5 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.4 1.3 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.3 3.8 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 7.4 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.6 GO:0070269 pyroptosis(GO:0070269)
0.2 6.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.2 0.5 GO:0016488 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.2 3.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 3.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.9 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 1.9 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 1.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.7 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.8 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 1.3 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0010260 organ senescence(GO:0010260)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.7 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.6 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 1.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.1 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 2.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 1.4 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 1.8 GO:0045576 mast cell activation(GO:0045576)
0.0 0.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.8 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 2.1 GO:0018022 peptidyl-lysine methylation(GO:0018022)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0036398 TCR signalosome(GO:0036398)
0.3 1.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.2 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 4.8 GO:0042588 zymogen granule(GO:0042588)
0.2 0.7 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 1.4 GO:0060091 kinocilium(GO:0060091)
0.1 3.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 5.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.3 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.9 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.7 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 3.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 8.1 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 GO:0046625 sphingolipid binding(GO:0046625)
0.2 1.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 3.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 0.5 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.2 1.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 4.8 GO:0031489 myosin V binding(GO:0031489)
0.1 3.9 GO:0008494 translation activator activity(GO:0008494)
0.1 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.7 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 1.7 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 2.1 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 5.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 7.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.1 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 4.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 2.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 4.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL