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Illumina Body Map 2 (GSE30611)

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Results for CACAGUG

Z-value: 0.70

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miRNA associated with seed CACAGUG

NamemiRBASE accession
hsa-miR-128-3p
MIMAT0000424
hsa-miR-216a-3p
MIMAT0022844
hsa-miR-3681-3p
MIMAT0018109

Activity profile of CACAGUG motif

Sorted Z-values of CACAGUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_34621065 3.22 ENST00000257831.8
EHF
ETS homologous factor
chr18_+_22169580 2.13 ENST00000269216.10
GATA6
GATA binding protein 6
chrX_+_105822531 2.03 ENST00000243300.14
ENST00000536164.5
NRK
Nik related kinase
chr1_-_56579555 2.03 ENST00000371250.4
PLPP3
phospholipid phosphatase 3
chr17_+_49495286 1.93 ENST00000172229.8
NGFR
nerve growth factor receptor
chr1_-_67833448 1.79 ENST00000370982.4
GNG12
G protein subunit gamma 12
chr5_+_172641241 1.79 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr1_+_116909869 1.75 ENST00000393203.3
PTGFRN
prostaglandin F2 receptor inhibitor
chr9_+_130172343 1.71 ENST00000372398.6
NCS1
neuronal calcium sensor 1
chr20_+_10218808 1.67 ENST00000254976.7
ENST00000304886.6
SNAP25
synaptosome associated protein 25
chr8_+_40153475 1.63 ENST00000315792.5
TCIM
transcriptional and immune response regulator
chr14_-_29927801 1.61 ENST00000331968.11
PRKD1
protein kinase D1
chr15_+_96330691 1.58 ENST00000394166.8
NR2F2
nuclear receptor subfamily 2 group F member 2
chr9_+_114155526 1.55 ENST00000356083.8
COL27A1
collagen type XXVII alpha 1 chain
chr17_+_12665882 1.53 ENST00000425538.6
MYOCD
myocardin
chr1_-_94927079 1.51 ENST00000370206.9
ENST00000394202.8
CNN3
calponin 3
chr5_-_58460076 1.49 ENST00000274289.8
ENST00000617412.1
PLK2
polo like kinase 2
chr22_+_41560973 1.48 ENST00000306149.12
CSDC2
cold shock domain containing C2
chr7_-_27143672 1.45 ENST00000222726.4
HOXA5
homeobox A5
chr10_-_88952763 1.43 ENST00000224784.10
ACTA2
actin alpha 2, smooth muscle
chr1_-_205356894 1.40 ENST00000367155.8
KLHDC8A
kelch domain containing 8A
chr15_-_63381835 1.40 ENST00000344366.7
ENST00000178638.8
ENST00000422263.2
CA12
carbonic anhydrase 12
chr20_+_2692736 1.40 ENST00000380648.9
ENST00000497450.5
EBF4
EBF family member 4
chr1_-_225653045 1.39 ENST00000366843.6
ENST00000366844.7
ENAH
ENAH actin regulator
chr8_-_41309434 1.39 ENST00000220772.8
SFRP1
secreted frizzled related protein 1
chr2_-_27495185 1.38 ENST00000264703.4
FNDC4
fibronectin type III domain containing 4
chr3_+_139935176 1.36 ENST00000458420.7
CLSTN2
calsyntenin 2
chr19_+_15107369 1.36 ENST00000342784.7
ENST00000597977.5
ENST00000600440.5
SYDE1
synapse defective Rho GTPase homolog 1
chr5_-_38595396 1.33 ENST00000263409.8
LIFR
LIF receptor subunit alpha
chr1_+_65147514 1.32 ENST00000545314.5
AK4
adenylate kinase 4
chr15_-_37098281 1.30 ENST00000559085.5
ENST00000397624.7
MEIS2
Meis homeobox 2
chr4_+_84583037 1.25 ENST00000295887.6
CDS1
CDP-diacylglycerol synthase 1
chr4_+_54229261 1.17 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
PDGFRA
platelet derived growth factor receptor alpha
chr6_+_135851681 1.10 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr15_+_32717994 1.10 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
GREM1
gremlin 1, DAN family BMP antagonist
chr4_-_110198650 1.10 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr14_+_99793375 1.10 ENST00000262233.11
ENST00000556714.5
EML1
EMAP like 1
chr5_-_180353317 1.09 ENST00000253778.13
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr4_-_173530219 1.08 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr6_+_127118657 1.07 ENST00000356698.9
RSPO3
R-spondin 3
chr8_-_80874771 1.07 ENST00000327835.7
ZNF704
zinc finger protein 704
chr9_+_113876282 1.07 ENST00000374126.9
ENST00000615615.4
ENST00000288466.11
ZNF618
zinc finger protein 618
chrX_+_103376488 1.07 ENST00000361298.9
BEX3
brain expressed X-linked 3
chr7_+_94656325 1.05 ENST00000482108.1
ENST00000488574.5
ENST00000612748.1
ENST00000613043.1
PEG10
paternally expressed 10
chr1_+_109910840 1.05 ENST00000329608.11
ENST00000488198.5
CSF1
colony stimulating factor 1
chr20_+_36092698 1.05 ENST00000430276.5
ENST00000373950.6
ENST00000373946.7
ENST00000441639.5
ENST00000628415.2
ENST00000452261.5
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr17_-_8630713 1.02 ENST00000411957.1
ENST00000360416.8
MYH10
myosin heavy chain 10
chr2_+_188974364 1.00 ENST00000304636.9
ENST00000317840.9
COL3A1
collagen type III alpha 1 chain
chr10_-_15719885 1.00 ENST00000378076.4
ITGA8
integrin subunit alpha 8
chr1_-_154502402 1.00 ENST00000304760.3
SHE
Src homology 2 domain containing E
chr14_-_91947383 1.00 ENST00000267620.14
FBLN5
fibulin 5
chr1_-_51297990 0.99 ENST00000530004.5
TTC39A
tetratricopeptide repeat domain 39A
chr16_-_65121930 0.99 ENST00000566827.5
ENST00000394156.7
ENST00000268603.9
ENST00000562998.1
CDH11
cadherin 11
chr12_+_54028433 0.99 ENST00000243108.5
HOXC6
homeobox C6
chr12_-_76878985 0.98 ENST00000547435.1
ENST00000552330.5
ENST00000311083.10
ENST00000546966.5
CSRP2
cysteine and glycine rich protein 2
chr10_+_58512864 0.97 ENST00000373886.8
BICC1
BicC family RNA binding protein 1
chr1_+_160400543 0.96 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr9_+_116153783 0.94 ENST00000328252.4
PAPPA
pappalysin 1
chr14_+_37197921 0.93 ENST00000684589.1
ENST00000327441.11
MIPOL1
mirror-image polydactyly 1
chr21_-_38498415 0.93 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chr12_-_48788995 0.93 ENST00000550422.5
ENST00000357869.8
ADCY6
adenylate cyclase 6
chr17_-_48615261 0.93 ENST00000239144.5
HOXB8
homeobox B8
chr9_-_137302264 0.92 ENST00000356628.4
NRARP
NOTCH regulated ankyrin repeat protein
chr16_-_70685975 0.90 ENST00000338779.11
MTSS2
MTSS I-BAR domain containing 2
chr10_-_89643870 0.89 ENST00000322191.10
ENST00000342512.3
PANK1
pantothenate kinase 1
chr6_+_41638438 0.89 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr1_-_116667668 0.88 ENST00000369486.8
ENST00000369483.5
IGSF3
immunoglobulin superfamily member 3
chr11_+_120210991 0.87 ENST00000328965.9
OAF
out at first homolog
chr8_+_133191060 0.87 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
CCN4
cellular communication network factor 4
chr4_+_183905266 0.84 ENST00000308497.9
STOX2
storkhead box 2
chr4_-_22516001 0.83 ENST00000334304.10
ADGRA3
adhesion G protein-coupled receptor A3
chr1_-_94541746 0.83 ENST00000334047.12
F3
coagulation factor III, tissue factor
chr5_-_122078249 0.83 ENST00000231004.5
LOX
lysyl oxidase
chrX_-_54357993 0.82 ENST00000375169.7
ENST00000354646.6
WNK3
WNK lysine deficient protein kinase 3
chr19_-_2721332 0.81 ENST00000588128.1
ENST00000323469.5
DIRAS1
DIRAS family GTPase 1
chr7_+_116672187 0.80 ENST00000318493.11
ENST00000397752.8
MET
MET proto-oncogene, receptor tyrosine kinase
chr2_+_43637247 0.80 ENST00000282406.9
PLEKHH2
pleckstrin homology, MyTH4 and FERM domain containing H2
chr5_+_34656288 0.80 ENST00000265109.8
RAI14
retinoic acid induced 14
chr17_+_9021501 0.79 ENST00000173229.7
NTN1
netrin 1
chr4_+_81030700 0.79 ENST00000282701.4
BMP3
bone morphogenetic protein 3
chr1_+_115641945 0.79 ENST00000355485.7
ENST00000369510.8
VANGL1
VANGL planar cell polarity protein 1
chr17_+_74987581 0.78 ENST00000337231.5
CDR2L
cerebellar degeneration related protein 2 like
chr15_+_73052449 0.76 ENST00000261908.11
NEO1
neogenin 1
chr14_-_59465327 0.76 ENST00000395116.1
GPR135
G protein-coupled receptor 135
chr12_-_120369156 0.73 ENST00000257552.7
MSI1
musashi RNA binding protein 1
chr3_+_36380477 0.72 ENST00000457375.6
ENST00000273183.8
ENST00000434649.1
STAC
SH3 and cysteine rich domain
chr2_+_205682491 0.71 ENST00000360409.7
ENST00000450507.5
ENST00000357785.10
ENST00000417189.5
NRP2
neuropilin 2
chr6_-_46325641 0.71 ENST00000330430.10
ENST00000405162.2
RCAN2
regulator of calcineurin 2
chr12_+_20368495 0.71 ENST00000359062.4
PDE3A
phosphodiesterase 3A
chr3_-_31981228 0.70 ENST00000396556.7
ENST00000438237.6
OSBPL10
oxysterol binding protein like 10
chr8_-_90985198 0.69 ENST00000517562.3
C8orf88
chromosome 8 open reading frame 88
chr16_+_66366675 0.68 ENST00000341529.8
ENST00000649567.1
CDH5
cadherin 5
chr1_-_37034492 0.67 ENST00000373091.8
GRIK3
glutamate ionotropic receptor kainate type subunit 3
chr3_+_123067016 0.67 ENST00000316218.12
PDIA5
protein disulfide isomerase family A member 5
chr6_-_119078642 0.67 ENST00000621231.4
ENST00000338891.12
FAM184A
family with sequence similarity 184 member A
chr1_+_205504592 0.67 ENST00000506784.5
ENST00000360066.6
CDK18
cyclin dependent kinase 18
chr15_+_40929338 0.67 ENST00000249749.7
DLL4
delta like canonical Notch ligand 4
chr20_-_10673987 0.66 ENST00000254958.10
JAG1
jagged canonical Notch ligand 1
chr21_-_41926680 0.66 ENST00000329623.11
C2CD2
C2 calcium dependent domain containing 2
chr2_-_9003657 0.66 ENST00000462696.1
ENST00000305997.8
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr12_+_78864768 0.65 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr20_-_14337602 0.65 ENST00000378053.3
ENST00000341420.5
FLRT3
fibronectin leucine rich transmembrane protein 3
chr12_-_12267003 0.65 ENST00000535731.1
ENST00000261349.9
LRP6
LDL receptor related protein 6
chr4_+_20251896 0.64 ENST00000504154.6
SLIT2
slit guidance ligand 2
chr2_-_150487658 0.63 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
RND3
Rho family GTPase 3
chr6_-_56247525 0.62 ENST00000244728.10
COL21A1
collagen type XXI alpha 1 chain
chr9_+_106863121 0.62 ENST00000472574.1
ENST00000277225.10
ZNF462
zinc finger protein 462
chr8_+_28494190 0.62 ENST00000537916.2
ENST00000240093.8
ENST00000523546.1
FZD3
frizzled class receptor 3
chr2_-_165794190 0.62 ENST00000392701.8
ENST00000422973.1
GALNT3
polypeptide N-acetylgalactosaminyltransferase 3
chr16_+_77788554 0.61 ENST00000302536.3
VAT1L
vesicle amine transport 1 like
chr10_-_79445617 0.60 ENST00000372336.4
ZCCHC24
zinc finger CCHC-type containing 24
chr11_-_115504389 0.60 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
CADM1
cell adhesion molecule 1
chr6_+_1312090 0.60 ENST00000296839.5
FOXQ1
forkhead box Q1
chrX_+_17375230 0.60 ENST00000380060.7
NHS
NHS actin remodeling regulator
chr14_+_100726883 0.59 ENST00000341267.9
ENST00000331224.10
ENST00000556051.1
DLK1
delta like non-canonical Notch ligand 1
chr1_-_23559490 0.59 ENST00000374561.6
ID3
inhibitor of DNA binding 3, HLH protein
chr5_-_116574802 0.59 ENST00000343348.11
SEMA6A
semaphorin 6A
chr2_+_42494547 0.58 ENST00000405592.5
MTA3
metastasis associated 1 family member 3
chr5_+_132813283 0.58 ENST00000378693.4
SOWAHA
sosondowah ankyrin repeat domain family member A
chr9_+_121651594 0.58 ENST00000408936.7
DAB2IP
DAB2 interacting protein
chr8_-_90646074 0.58 ENST00000458549.7
TMEM64
transmembrane protein 64
chr8_+_75539862 0.57 ENST00000396423.4
HNF4G
hepatocyte nuclear factor 4 gamma
chr22_-_28679865 0.56 ENST00000397906.6
TTC28
tetratricopeptide repeat domain 28
chr12_+_109713817 0.56 ENST00000538780.2
FAM222A
family with sequence similarity 222 member A
chr1_+_200027702 0.55 ENST00000367362.8
NR5A2
nuclear receptor subfamily 5 group A member 2
chr10_+_102714595 0.55 ENST00000602647.5
ENST00000602439.5
ENST00000602764.5
ENST00000369893.10
SFXN2
sideroflexin 2
chr1_+_113390495 0.55 ENST00000307546.14
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr1_+_162561504 0.54 ENST00000271469.7
ENST00000367926.8
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1
chrX_+_23334841 0.54 ENST00000379361.5
PTCHD1
patched domain containing 1
chr4_+_51843063 0.54 ENST00000381441.7
ENST00000334635.10
DCUN1D4
defective in cullin neddylation 1 domain containing 4
chr12_-_105084439 0.53 ENST00000258494.14
ALDH1L2
aldehyde dehydrogenase 1 family member L2
chr18_-_26090584 0.52 ENST00000415083.7
SS18
SS18 subunit of BAF chromatin remodeling complex
chr7_-_30026617 0.52 ENST00000222803.10
FKBP14
FKBP prolyl isomerase 14
chr17_+_58755821 0.51 ENST00000308249.4
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent 1E
chr4_+_5051471 0.51 ENST00000282908.10
STK32B
serine/threonine kinase 32B
chr8_+_17027230 0.51 ENST00000318063.10
MICU3
mitochondrial calcium uptake family member 3
chr12_-_120469655 0.50 ENST00000229390.8
SRSF9
serine and arginine rich splicing factor 9
chr6_+_142301854 0.50 ENST00000230173.10
ENST00000367608.6
ADGRG6
adhesion G protein-coupled receptor G6
chr19_-_17245889 0.50 ENST00000291442.4
NR2F6
nuclear receptor subfamily 2 group F member 6
chr3_+_10992717 0.49 ENST00000642767.1
ENST00000425938.6
ENST00000642515.1
ENST00000643498.1
ENST00000646072.1
ENST00000646570.1
ENST00000287766.10
ENST00000645281.1
ENST00000642820.1
ENST00000645054.1
ENST00000642735.1
ENST00000646022.1
ENST00000645776.1
ENST00000645592.1
ENST00000646924.1
ENST00000645974.1
ENST00000644314.1
ENST00000642639.1
ENST00000646060.1
ENST00000642201.1
ENST00000646487.1
ENST00000647194.1
ENST00000646088.1
SLC6A1
solute carrier family 6 member 1
chr8_-_12755457 0.47 ENST00000398246.8
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr21_+_17513119 0.47 ENST00000356275.10
ENST00000400165.5
ENST00000400169.1
CXADR
CXADR Ig-like cell adhesion molecule
chr2_-_197499826 0.47 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
HSPD1
heat shock protein family D (Hsp60) member 1
chr21_+_31873010 0.46 ENST00000270112.7
HUNK
hormonally up-regulated Neu-associated kinase
chr11_+_112961402 0.46 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
NCAM1
neural cell adhesion molecule 1
chr1_+_70411180 0.45 ENST00000411986.6
CTH
cystathionine gamma-lyase
chr1_-_71047803 0.45 ENST00000370932.6
ENST00000628037.2
ENST00000351052.9
ENST00000354608.9
ENST00000370924.4
PTGER3
prostaglandin E receptor 3
chr17_+_2055094 0.45 ENST00000399849.4
ENST00000619757.5
HIC1
HIC ZBTB transcriptional repressor 1
chr15_+_97960692 0.45 ENST00000268042.7
ARRDC4
arrestin domain containing 4
chr12_+_70366277 0.45 ENST00000258111.5
KCNMB4
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr5_+_149581368 0.44 ENST00000333677.7
ARHGEF37
Rho guanine nucleotide exchange factor 37
chr17_+_40287861 0.44 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
CDC6
cell division cycle 6
chr18_+_70288991 0.44 ENST00000397942.4
SOCS6
suppressor of cytokine signaling 6
chrX_+_65488735 0.44 ENST00000338957.4
ZC3H12B
zinc finger CCCH-type containing 12B
chr3_-_165196369 0.44 ENST00000475390.2
SLITRK3
SLIT and NTRK like family member 3
chr15_+_84235773 0.44 ENST00000510439.7
ENST00000422563.6
GOLGA6L4
golgin A6 family like 4
chr2_-_163735989 0.43 ENST00000333129.4
ENST00000409634.5
FIGN
fidgetin, microtubule severing factor
chr6_-_165662100 0.43 ENST00000366882.6
PDE10A
phosphodiesterase 10A
chr6_+_41546340 0.43 ENST00000307972.10
ENST00000373063.7
FOXP4
forkhead box P4
chr6_+_117907226 0.43 ENST00000360388.9
SLC35F1
solute carrier family 35 member F1
chr6_-_99425269 0.43 ENST00000647811.1
ENST00000481229.2
ENST00000369239.10
ENST00000681611.1
ENST00000681615.1
ENST00000438806.5
PNISR
PNN interacting serine and arginine rich protein
chr9_+_100442271 0.43 ENST00000502978.1
MSANTD3-TMEFF1
MSANTD3-TMEFF1 readthrough
chrX_-_25015924 0.43 ENST00000379044.5
ARX
aristaless related homeobox
chr18_+_23135452 0.42 ENST00000580153.5
ENST00000256925.12
CABLES1
Cdk5 and Abl enzyme substrate 1
chr22_-_38844020 0.42 ENST00000333039.4
NPTXR
neuronal pentraxin receptor
chr7_-_27174274 0.42 ENST00000283921.5
HOXA10
homeobox A10
chr3_+_37861926 0.41 ENST00000443503.6
CTDSPL
CTD small phosphatase like
chr21_-_43427131 0.41 ENST00000270162.8
SIK1
salt inducible kinase 1
chr22_+_45671798 0.41 ENST00000381061.8
ENST00000252934.10
ATXN10
ataxin 10
chr4_+_114598738 0.41 ENST00000507710.1
ENST00000310836.11
UGT8
UDP glycosyltransferase 8
chr19_+_32405789 0.40 ENST00000586987.5
DPY19L3
dpy-19 like C-mannosyltransferase 3
chr17_-_52159983 0.40 ENST00000575181.1
ENST00000570565.5
ENST00000442502.6
CA10
carbonic anhydrase 10
chr5_+_52989314 0.40 ENST00000296585.10
ITGA2
integrin subunit alpha 2
chr4_-_13544506 0.39 ENST00000382438.6
NKX3-2
NK3 homeobox 2
chr5_+_51383394 0.39 ENST00000230658.12
ISL1
ISL LIM homeobox 1
chr12_-_70637405 0.39 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
PTPRB
protein tyrosine phosphatase receptor type B
chr9_-_14314067 0.39 ENST00000397575.7
NFIB
nuclear factor I B
chr21_-_26967057 0.39 ENST00000284987.6
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr2_+_46698909 0.38 ENST00000650611.1
ENST00000306503.5
LINC01118
SOCS5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr7_+_100612522 0.38 ENST00000393950.7
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr4_-_39638846 0.38 ENST00000295958.10
SMIM14
small integral membrane protein 14
chr13_-_110561668 0.38 ENST00000267328.5
RAB20
RAB20, member RAS oncogene family
chr11_+_59172116 0.38 ENST00000227451.4
DTX4
deltex E3 ubiquitin ligase 4
chr19_+_51311638 0.38 ENST00000270642.9
IGLON5
IgLON family member 5
chr2_+_231395702 0.38 ENST00000287590.6
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr5_-_177554545 0.37 ENST00000514747.6
FAM193B
family with sequence similarity 193 member B
chr2_+_147845020 0.37 ENST00000241416.12
ACVR2A
activin A receptor type 2A
chr10_-_112183698 0.37 ENST00000369425.5
ENST00000348367.9
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_-_86991135 0.37 ENST00000398399.7
VGLL3
vestigial like family member 3
chr11_-_30586344 0.36 ENST00000358117.10
MPPED2
metallophosphoesterase domain containing 2
chr1_+_1020068 0.36 ENST00000379370.7
ENST00000620552.4
AGRN
agrin
chr19_-_14518383 0.36 ENST00000254322.3
ENST00000595139.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr3_-_142000353 0.36 ENST00000499676.5
TFDP2
transcription factor Dp-2
chr3_-_116445458 0.36 ENST00000490035.7
LSAMP
limbic system associated membrane protein
chr3_-_21751189 0.36 ENST00000281523.8
ZNF385D
zinc finger protein 385D
chr20_-_51768327 0.36 ENST00000311637.9
ENST00000338821.6
ATP9A
ATPase phospholipid transporting 9A (putative)
chr6_+_148747016 0.36 ENST00000367463.5
UST
uronyl 2-sulfotransferase
chr3_-_98901656 0.35 ENST00000326840.11
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr1_+_63773966 0.35 ENST00000371079.6
ENST00000371080.5
ROR1
receptor tyrosine kinase like orphan receptor 1
chr7_-_155812454 0.35 ENST00000297261.7
SHH
sonic hedgehog signaling molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of CACAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.5 2.1 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.5 2.6 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.5 2.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.4 2.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 1.7 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.4 1.6 GO:0009956 radial pattern formation(GO:0009956)
0.4 1.4 GO:0060535 bronchiole development(GO:0060435) trachea cartilage morphogenesis(GO:0060535)
0.3 1.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 1.8 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.3 1.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 1.4 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.3 1.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.3 1.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 1.4 GO:0072144 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.2 1.2 GO:0072275 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 1.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.6 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.2 1.0 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.2 0.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.3 GO:0060458 right lung development(GO:0060458)
0.2 0.7 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
0.2 0.5 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.2 0.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 0.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 0.5 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 2.1 GO:0008354 germ cell migration(GO:0008354)
0.1 1.6 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700)
0.1 1.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.4 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.4 GO:0071657 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.1 1.0 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.6 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 1.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 1.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.3 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 0.4 GO:0044691 tooth eruption(GO:0044691)
0.1 0.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.3 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 1.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.9 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.6 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.3 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 1.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 1.5 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.3 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.6 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.4 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.9 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.2 GO:1904782 negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782)
0.1 1.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.7 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.3 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 0.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.4 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.5 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 1.0 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.6 GO:0021794 thalamus development(GO:0021794)
0.0 0.4 GO:2000791 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.0 0.3 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0006549 allantoin metabolic process(GO:0000255) isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.5 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.6 GO:0030903 notochord development(GO:0030903)
0.0 0.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 1.1 GO:0007625 grooming behavior(GO:0007625)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.5 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 1.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.0 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.2 1.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.0 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 0.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 2.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.0 GO:0097513 myosin II filament(GO:0097513)
0.1 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.0 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.6 GO:1990032 parallel fiber(GO:1990032)
0.1 0.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 2.4 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 1.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 0.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 3.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0071757 hexameric IgM immunoglobulin complex(GO:0071757)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.3 1.3 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.3 1.9 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.3 1.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 1.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.2 1.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.6 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 1.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 1.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.4 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.8 GO:0042301 phosphate ion binding(GO:0042301)
0.1 1.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 0.7 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 1.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711) BMP receptor activity(GO:0098821)
0.0 1.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 8.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 3.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 1.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 2.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 3.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis