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Illumina Body Map 2 (GSE30611)

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Results for CDX2

Z-value: 0.61

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Transcription factors associated with CDX2

Gene Symbol Gene ID Gene Info
ENSG00000165556.10 caudal type homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX2hg38_v1_chr13_-_27969295_27969350-0.057.9e-01Click!

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_71784046 2.23 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr16_+_66579448 1.98 ENST00000379486.6
ENST00000268595.3
CKLF like MARVEL transmembrane domain containing 2
chr16_+_72056153 1.67 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
haptoglobin
chr9_-_101442403 1.60 ENST00000648758.1
aldolase, fructose-bisphosphate B
chr4_+_154563003 1.43 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr7_+_80646305 1.39 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr18_+_3252267 1.34 ENST00000536605.1
ENST00000580887.5
myosin light chain 12A
chr7_+_80646436 1.28 ENST00000419819.2
CD36 molecule
chr7_+_80646347 1.15 ENST00000413265.5
CD36 molecule
chr22_+_32059165 1.06 ENST00000543737.2
solute carrier family 5 member 1
chr1_+_154429315 1.04 ENST00000476006.5
interleukin 6 receptor
chr7_+_129144691 0.99 ENST00000486685.3
tetraspanin 33
chr20_-_7940444 0.94 ENST00000378789.4
hydroxyacid oxidase 1
chr1_+_192158448 0.93 ENST00000367460.4
regulator of G protein signaling 18
chr18_+_3252208 0.91 ENST00000578562.6
myosin light chain 12A
chr3_+_125969172 0.90 ENST00000514116.6
ENST00000513830.5
rhophilin associated tail protein 1B
chr17_+_47209338 0.89 ENST00000393450.5
myosin light chain 4
chr17_+_59940908 0.87 ENST00000591035.1
novel protein
chr1_+_74235377 0.86 ENST00000326637.8
TNNI3 interacting kinase
chr19_+_926001 0.84 ENST00000263620.8
AT-rich interaction domain 3A
chr11_+_111245725 0.82 ENST00000280325.7
chromosome 11 open reading frame 53
chr6_+_25754699 0.82 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr11_-_93537903 0.79 ENST00000527149.5
single-pass membrane protein with coiled-coil domains 4
chr3_-_123991352 0.79 ENST00000184183.8
rhophilin associated tail protein 1
chr2_-_210303608 0.76 ENST00000341685.8
myosin light chain 1
chr17_-_48613468 0.76 ENST00000498634.2
homeobox B8
chr1_+_151766655 0.76 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr19_+_47994625 0.75 ENST00000339841.7
epididymal sperm binding protein 1
chr19_+_47994696 0.74 ENST00000596043.5
ENST00000597519.5
epididymal sperm binding protein 1
chr12_+_54284258 0.73 ENST00000677666.1
heterogeneous nuclear ribonucleoprotein A1
chr16_+_68085861 0.71 ENST00000570212.5
ENST00000562926.5
nuclear factor of activated T cells 3
chrX_-_15600953 0.71 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
angiotensin I converting enzyme 2
chr3_+_63967738 0.67 ENST00000484332.1
ataxin 7
chr3_-_123992046 0.67 ENST00000467907.5
ENST00000459660.5
ENST00000495093.1
ENST00000460743.5
ENST00000405845.7
ENST00000484329.1
ENST00000479867.1
ENST00000496145.5
rhophilin associated tail protein 1
chr6_+_111087495 0.66 ENST00000612036.4
ENST00000368851.10
solute carrier family 16 member 10
chrX_+_106693751 0.66 ENST00000418562.5
ring finger protein 128
chr15_-_55249029 0.66 ENST00000566877.5
RAB27A, member RAS oncogene family
chr17_+_47209375 0.65 ENST00000572303.1
myosin light chain 4
chr13_+_108269880 0.64 ENST00000542136.1
TNF superfamily member 13b
chr19_+_14031746 0.63 ENST00000263379.4
interleukin 27 receptor subunit alpha
chr20_+_44355692 0.62 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr1_+_241532121 0.61 ENST00000366558.7
kynurenine 3-monooxygenase
chr12_-_112006024 0.61 ENST00000550800.6
ENST00000550037.5
ENST00000549425.5
transmembrane protein 116
chr7_-_130441136 0.61 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr17_-_40799939 0.61 ENST00000306658.8
keratin 28
chr12_+_45292674 0.60 ENST00000679426.1
ENST00000441606.2
anoctamin 6
chrM_+_10464 0.59 ENST00000361335.1
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L
chr14_+_21825453 0.59 ENST00000390432.2
T cell receptor alpha variable 10
chr10_+_92691813 0.59 ENST00000472590.6
hematopoietically expressed homeobox
chr3_+_125969214 0.56 ENST00000508088.1
rhophilin associated tail protein 1B
chr17_-_41489907 0.56 ENST00000328119.11
keratin 36
chr12_-_112005963 0.56 ENST00000550233.1
transmembrane protein 116
chr1_+_51102238 0.56 ENST00000467127.5
chromosome 1 open reading frame 185
chr3_+_125969152 0.56 ENST00000251776.8
ENST00000504401.1
rhophilin associated tail protein 1B
chr3_+_172039556 0.55 ENST00000415807.7
ENST00000421757.5
fibronectin type III domain containing 3B
chr9_-_130939205 0.54 ENST00000372338.9
fibrinogen C domain containing 1
chr3_-_51779187 0.54 ENST00000398780.5
ENST00000668964.1
ENST00000667863.2
ENST00000647442.1
IQ motif containing F6
chr1_+_51102221 0.54 ENST00000648827.1
ENST00000371759.7
chromosome 1 open reading frame 185
chr4_+_168711416 0.54 ENST00000649826.1
palladin, cytoskeletal associated protein
chr2_+_149118169 0.54 ENST00000450639.5
LY6/PLAUR domain containing 6B
chr3_-_172523423 0.53 ENST00000241261.7
TNF superfamily member 10
chr12_-_52434363 0.53 ENST00000252245.6
keratin 75
chr4_-_39977836 0.53 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr6_+_89081787 0.53 ENST00000354922.3
proline rich nuclear receptor coactivator 1
chr14_-_60486021 0.53 ENST00000555476.5
ENST00000321731.8
chromosome 14 open reading frame 39
chr7_-_80512041 0.52 ENST00000398291.4
G protein subunit alpha transducin 3
chr4_+_70397931 0.52 ENST00000399575.7
opiorphin prepropeptide
chr12_+_1691011 0.52 ENST00000357103.5
adiponectin receptor 2
chr8_-_20183127 0.51 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr7_+_142111739 0.51 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr17_-_48728705 0.49 ENST00000290295.8
homeobox B13
chr3_-_46812558 0.49 ENST00000641183.1
ENST00000460241.2
novel transcript
novel protein identical to PRSS50
chr3_-_172523460 0.49 ENST00000420541.6
TNF superfamily member 10
chr20_-_31406207 0.48 ENST00000376314.3
defensin beta 121
chr1_-_53889766 0.48 ENST00000371399.5
ENST00000072644.7
Yip1 domain family member 1
chr12_+_14408482 0.48 ENST00000541056.1
activating transcription factor 7 interacting protein
chr10_+_102226293 0.48 ENST00000370005.4
ELOVL fatty acid elongase 3
chr7_-_143408848 0.47 ENST00000275815.4
EPH receptor A1
chr2_-_169031317 0.47 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr16_-_66873233 0.47 ENST00000561579.6
NEDD8 activating enzyme E1 subunit 1
chr2_-_51032151 0.46 ENST00000628515.2
neurexin 1
chr14_-_56805648 0.44 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chr6_+_143450797 0.44 ENST00000367591.5
ENST00000367592.5
peroxisomal biogenesis factor 3
chr3_-_18438678 0.43 ENST00000414509.5
SATB homeobox 1
chr17_-_29761415 0.43 ENST00000649863.1
slingshot protein phosphatase 2
chr9_-_83956677 0.43 ENST00000376344.8
chromosome 9 open reading frame 64
chr3_-_185821092 0.42 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr11_+_60378494 0.42 ENST00000534016.5
membrane spanning 4-domains A7
chr7_+_130344810 0.42 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
carboxypeptidase A5
chr11_+_60280531 0.39 ENST00000532114.6
membrane spanning 4-domains A4A
chr10_-_127892930 0.39 ENST00000368671.4
clarin 3
chr15_+_40594001 0.38 ENST00000346991.9
ENST00000528975.5
kinetochore scaffold 1
chr16_-_21652598 0.38 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr16_-_1884231 0.36 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr3_-_18438767 0.36 ENST00000454909.6
SATB homeobox 1
chr6_-_166168645 0.36 ENST00000461348.2
T-box transcription factor T
chr4_-_139301204 0.36 ENST00000505036.5
ENST00000539002.5
ENST00000544855.5
NADH:ubiquinone oxidoreductase subunit C1
chr8_+_75539862 0.36 ENST00000396423.4
hepatocyte nuclear factor 4 gamma
chr4_+_186227501 0.36 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr12_+_32534287 0.35 ENST00000525053.6
FYVE, RhoGEF and PH domain containing 4
chr11_+_60378475 0.35 ENST00000358246.5
membrane spanning 4-domains A7
chr6_-_166168612 0.35 ENST00000296946.6
T-box transcription factor T
chr16_+_56748206 0.35 ENST00000566678.1
nucleoporin 93
chr3_+_57890011 0.35 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chrX_+_106693838 0.35 ENST00000324342.7
ring finger protein 128
chr20_+_31514410 0.35 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr10_+_46286997 0.34 ENST00000620264.5
ANTXR like
chr20_+_4721901 0.34 ENST00000305817.3
prion like protein doppel
chr4_+_70518583 0.34 ENST00000504451.1
amelotin
chr12_-_112005999 0.34 ENST00000546962.5
transmembrane protein 116
chr8_-_20183090 0.34 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr8_+_75539893 0.34 ENST00000674002.1
hepatocyte nuclear factor 4 gamma
chr3_-_108953870 0.34 ENST00000261047.8
guanylate cyclase activator 1C
chr9_+_131190119 0.33 ENST00000483497.6
nucleoporin 214
chr6_-_27814757 0.33 ENST00000333151.5
H2A clustered histone 14
chr1_+_26472405 0.33 ENST00000361427.6
high mobility group nucleosomal binding domain 2
chr7_+_64249118 0.33 ENST00000255746.7
zinc finger protein 679
chr5_-_36001006 0.33 ENST00000625798.2
UDP glycosyltransferase family 3 member A1
chr9_+_120792403 0.33 ENST00000464488.3
beta-1,3-galactosyltransferase 9
chr11_+_60280577 0.32 ENST00000679988.1
membrane spanning 4-domains A4A
chr1_+_178725147 0.31 ENST00000367634.6
Ral GEF with PH domain and SH3 binding motif 2
chr6_-_22302797 0.31 ENST00000651757.1
prolactin
chr4_+_70518563 0.31 ENST00000339336.9
amelotin
chr9_+_97412062 0.31 ENST00000355295.5
tudor domain containing 7
chr6_+_133953210 0.30 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr6_-_166168700 0.30 ENST00000366871.7
T-box transcription factor T
chr6_+_104940866 0.30 ENST00000637759.1
lin-28 homolog B
chr13_+_108269629 0.30 ENST00000430559.5
ENST00000375887.9
TNF superfamily member 13b
chr4_+_145680146 0.30 ENST00000438731.7
chromosome 4 open reading frame 51
chr1_+_26472459 0.30 ENST00000619352.4
high mobility group nucleosomal binding domain 2
chr5_+_148221641 0.29 ENST00000638059.1
MARCO like
chr4_-_77076288 0.29 ENST00000507788.2
cyclin I
chr1_-_237004440 0.29 ENST00000464121.3
metallothionein 1H like 1
chr11_+_112176364 0.29 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr12_-_10810168 0.29 ENST00000240691.4
taste 2 receptor member 9
chrX_-_15601077 0.27 ENST00000680121.1
angiotensin I converting enzyme 2
chr3_-_108953762 0.26 ENST00000393963.7
ENST00000471108.1
guanylate cyclase activator 1C
chr7_+_70766172 0.26 ENST00000644949.1
activator of transcription and developmental regulator AUTS2
chr11_-_5783355 0.26 ENST00000641181.1
olfactory receptor family 52 subfamily N member 5
chr17_-_29761390 0.26 ENST00000324677.12
slingshot protein phosphatase 2
chr6_-_22302826 0.26 ENST00000651245.1
prolactin
chr2_+_37950432 0.25 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chr4_-_155866277 0.25 ENST00000537611.3
acid sensing ion channel subunit family member 5
chr1_-_28058087 0.25 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr7_-_47539591 0.25 ENST00000442536.6
ENST00000458317.6
tensin 3
chr11_-_118342691 0.25 ENST00000300692.9
CD3d molecule
chr5_+_72848161 0.24 ENST00000506351.6
transportin 1
chr7_-_93148345 0.24 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chrX_-_13319952 0.24 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr19_+_20923222 0.24 ENST00000597314.5
ENST00000328178.13
ENST00000601924.5
zinc finger protein 85
chr7_-_144410227 0.24 ENST00000467773.1
ENST00000483238.5
NOBOX oogenesis homeobox
chr1_+_53014926 0.23 ENST00000430330.6
ENST00000408941.7
ENST00000478274.6
ENST00000484100.5
ENST00000435345.6
ENST00000488965.1
sterol carrier protein 2
chr19_-_45424364 0.23 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr10_+_46286345 0.23 ENST00000619553.4
ANTXR like
chr14_+_19930917 0.23 ENST00000641172.1
ENST00000641429.1
olfactory receptor family 4 subfamily K member 1
chr2_+_218782138 0.23 ENST00000258415.9
cytochrome P450 family 27 subfamily A member 1
chr19_+_48393657 0.23 ENST00000263269.4
glutamate ionotropic receptor NMDA type subunit 2D
chr5_-_148654130 0.23 ENST00000360693.7
5-hydroxytryptamine receptor 4
chr6_-_138512493 0.23 ENST00000533765.1
NHS like 1
chrM_+_10055 0.22 ENST00000361227.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
chr3_-_13022546 0.22 ENST00000646269.1
IQ motif and Sec7 domain ArfGEF 1
chr3_+_112990956 0.21 ENST00000383678.8
ENST00000383677.7
ENST00000619116.4
GTP binding protein 8 (putative)
chr1_+_248038172 0.20 ENST00000366479.4
olfactory receptor family 2 subfamily L member 2
chr1_+_12464912 0.20 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr4_-_68670648 0.19 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr10_-_113854368 0.19 ENST00000369305.1
DNA cross-link repair 1A
chr6_+_143126183 0.19 ENST00000458219.1
androgen induced 1
chr1_+_65419 0.19 ENST00000641515.2
olfactory receptor family 4 subfamily F member 5
chr3_-_9880250 0.18 ENST00000423850.5
ENST00000336832.7
ENST00000675828.1
ENST00000618572.4
ENST00000455015.6
cell death inducing DFFA like effector c
chr5_+_122129597 0.18 ENST00000514925.1
novel zinc finger protein
chr11_+_22666604 0.17 ENST00000454584.6
growth arrest specific 2
chr14_+_56117702 0.17 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr4_-_76023489 0.17 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr6_+_47698538 0.17 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr14_+_51989609 0.17 ENST00000556760.5
RNA transcription, translation and transport factor
chr6_+_47698574 0.17 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr12_-_76486061 0.17 ENST00000548341.5
oxysterol binding protein like 8
chr2_-_240821363 0.16 ENST00000675940.1
kinesin family member 1A
chr20_+_2295994 0.16 ENST00000381458.6
transglutaminase 3
chr8_+_7768977 0.16 ENST00000533716.2
family with sequence similarity 90 member A10, pseudogene
chr2_+_32165841 0.16 ENST00000357055.7
ENST00000435660.5
ENST00000440718.5
ENST00000379343.6
ENST00000282587.9
ENST00000406369.2
solute carrier family 30 member 6
chr12_-_21774688 0.16 ENST00000240662.3
potassium inwardly rectifying channel subfamily J member 8
chr1_+_220094086 0.16 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr8_+_7730739 0.16 ENST00000648174.1
family with sequence similarity 90 member A16, pseudogene
chr7_+_64207090 0.15 ENST00000429565.4
zinc finger protein 735
chr1_+_151762899 0.15 ENST00000635322.1
ENST00000321531.10
ornithine decarboxylase antizyme 3
chr4_-_168318770 0.15 ENST00000680771.1
ENST00000514995.2
DExD/H-box helicase 60
chr11_+_63838902 0.15 ENST00000377810.8
microtubule affinity regulating kinase 2
chr17_-_82840010 0.15 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr10_+_19048788 0.15 ENST00000454679.7
MAM and LDL receptor class A domain containing 1
chr16_+_4474690 0.14 ENST00000575051.5
ENST00000406590.6
heme oxygenase 2
chr6_+_27815010 0.14 ENST00000621112.2
H2B clustered histone 14
chr1_+_34176900 0.14 ENST00000488417.2
chromosome 1 open reading frame 94
chr3_+_148827800 0.14 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr4_+_70383123 0.14 ENST00000304915.8
submaxillary gland androgen regulated protein 3B
chr4_-_163613505 0.14 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr10_+_113854610 0.14 ENST00000369301.3
NHL repeat containing 2
chr8_+_12104389 0.13 ENST00000400085.7
zinc finger protein 705D
chr10_+_84173793 0.13 ENST00000372126.4
chromosome 10 open reading frame 99
chr9_-_83063135 0.13 ENST00000376447.4
RAS and EF-hand domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3 0.9 GO:0015847 putrescine transport(GO:0015847)
0.3 3.8 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.9 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 0.6 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 1.0 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.6 GO:0061011 hepatic duct development(GO:0061011)
0.2 1.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.6 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 1.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.2 0.6 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.8 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.7 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.1 1.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0016122 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 2.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 2.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.7 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 1.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.9 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.7 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0072560 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.0 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 1.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.4 GO:0007144 female meiosis I(GO:0007144)
0.0 0.6 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 2.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.7 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.7 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 1.7 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 3.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 3.1 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.4 1.6 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.3 3.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 0.9 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.3 0.9 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.3 1.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.3 1.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.8 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 0.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.2 0.5 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.2 1.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.7 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 0.5 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.6 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.5 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 2.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 2.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.5 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.6 GO:0017128 voltage-gated chloride channel activity(GO:0005247) phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 4.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells