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Illumina Body Map 2 (GSE30611)

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Results for CEBPE_CEBPD

Z-value: 2.34

Motif logo

Transcription factors associated with CEBPE_CEBPD

Gene Symbol Gene ID Gene Info
ENSG00000092067.6 CCAAT enhancer binding protein epsilon
ENSG00000221869.5 CCAAT enhancer binding protein delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPEhg38_v1_chr14_-_23119248_231192650.421.7e-02Click!
CEBPDhg38_v1_chr8_-_47738153_477381730.134.9e-01Click!

Activity profile of CEBPE_CEBPD motif

Sorted Z-values of CEBPE_CEBPD motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_18248662 20.45 ENST00000256733.9
serum amyloid A2
chr11_+_18266254 20.29 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr11_-_18248632 19.88 ENST00000524555.3
ENST00000528349.5
ENST00000526900.1
ENST00000529528.5
ENST00000414546.6
SAA2-SAA4 readthrough
serum amyloid A2
chr12_-_95996302 19.45 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr6_-_132734692 18.93 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr16_+_72054477 17.36 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr3_+_186613052 16.94 ENST00000411641.7
ENST00000273784.5
alpha 2-HS glycoprotein
chr15_+_58138368 15.68 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr3_+_186666003 15.50 ENST00000232003.5
histidine rich glycoprotein
chr6_+_131573219 15.11 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr10_-_93601228 13.63 ENST00000371464.8
retinol binding protein 4
chr10_-_80289647 13.50 ENST00000372213.8
methionine adenosyltransferase 1A
chr15_+_58138169 13.03 ENST00000558772.5
aquaporin 9
chr3_+_186717348 11.11 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr16_+_72063226 10.92 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
haptoglobin-related protein
chr12_-_95995920 10.42 ENST00000552509.5
histidine ammonia-lyase
chrX_+_139530730 10.37 ENST00000218099.7
coagulation factor IX
chr5_+_50667405 8.40 ENST00000505554.5
poly(ADP-ribose) polymerase family member 8
chr3_-_58214671 8.31 ENST00000460422.1
ENST00000483681.5
deoxyribonuclease 1 like 3
chr2_+_113127588 8.23 ENST00000409930.4
interleukin 1 receptor antagonist
chr1_+_154405326 8.10 ENST00000368485.8
interleukin 6 receptor
chrX_+_139530752 8.09 ENST00000394090.2
coagulation factor IX
chr1_+_196774813 8.07 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr3_-_149221811 7.91 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr17_-_7114648 7.91 ENST00000355035.9
asialoglycoprotein receptor 2
chr17_-_7114813 7.75 ENST00000254850.11
asialoglycoprotein receptor 2
chr4_-_154590735 7.49 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr14_-_69797232 7.45 ENST00000216540.5
solute carrier family 10 member 1
chr6_+_31927510 7.19 ENST00000447952.6
complement C2
chr3_+_46354072 7.02 ENST00000445132.3
ENST00000421659.1
C-C motif chemokine receptor 2
chr16_-_84618067 6.99 ENST00000262428.5
coactosin like F-actin binding protein 1
chr6_+_31927486 6.93 ENST00000442278.6
complement C2
chr1_+_192158448 6.92 ENST00000367460.4
regulator of G protein signaling 18
chrX_-_106038721 6.81 ENST00000372563.2
serpin family A member 7
chr4_-_184826030 6.61 ENST00000507295.5
ENST00000504900.5
ENST00000454703.6
acyl-CoA synthetase long chain family member 1
chr16_-_84618041 6.55 ENST00000564057.1
coactosin like F-actin binding protein 1
chr6_+_31927703 6.55 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr4_-_184825960 6.55 ENST00000281455.7
acyl-CoA synthetase long chain family member 1
chr14_-_22815421 6.53 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chr6_+_31927683 5.97 ENST00000456570.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr1_+_196888014 5.87 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr21_-_44914271 5.76 ENST00000522931.5
integrin subunit beta 2
chr13_-_46105009 5.69 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr20_+_57561103 5.64 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr19_+_11239602 5.62 ENST00000252453.12
angiopoietin like 8
chr10_-_112183698 5.51 ENST00000369425.5
ENST00000348367.9
glycerol-3-phosphate acyltransferase, mitochondrial
chr19_+_6887560 5.23 ENST00000250572.12
ENST00000381407.9
ENST00000450315.7
ENST00000312053.9
ENST00000381404.8
adhesion G protein-coupled receptor E1
chr19_-_40850442 5.20 ENST00000301141.10
cytochrome P450 family 2 subfamily A member 6
chrX_-_132413597 5.14 ENST00000394311.6
muscleblind like splicing regulator 3
chr16_-_30445865 5.14 ENST00000478753.5
selenophosphate synthetase 2
chr12_-_122716790 5.03 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chrX_-_132413567 5.00 ENST00000538204.5
ENST00000370849.7
muscleblind like splicing regulator 3
chr2_+_218382265 4.90 ENST00000233202.11
solute carrier family 11 member 1
chr1_-_1779976 4.82 ENST00000378625.5
NAD kinase
chr4_+_155854758 4.81 ENST00000506072.5
ENST00000507590.5
tryptophan 2,3-dioxygenase
chr5_-_39364484 4.78 ENST00000263408.5
complement C9
chr15_+_45635017 4.75 ENST00000260324.12
sulfide quinone oxidoreductase
chr20_-_22585451 4.71 ENST00000377115.4
forkhead box A2
chr12_-_122703346 4.67 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr1_+_154405193 4.63 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr11_-_59212869 4.62 ENST00000361050.4
macrophage expressed 1
chr5_-_140633167 4.32 ENST00000302014.11
CD14 molecule
chr14_-_22815493 4.29 ENST00000555911.1
solute carrier family 7 member 7
chr1_-_204213943 4.25 ENST00000308302.4
golgi transport 1A
chr3_-_120682215 4.18 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr14_-_22815856 4.14 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr15_+_45634721 4.12 ENST00000561735.5
sulfide quinone oxidoreductase
chr19_+_40991274 4.07 ENST00000324071.10
cytochrome P450 family 2 subfamily B member 6
chr14_-_22815801 4.03 ENST00000397532.9
solute carrier family 7 member 7
chr2_-_31414694 3.97 ENST00000379416.4
xanthine dehydrogenase
chr14_+_20469399 3.89 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr11_-_116792386 3.88 ENST00000433069.2
ENST00000542499.5
apolipoprotein A5
chr20_-_17682234 3.74 ENST00000377813.6
ENST00000377807.6
ENST00000360807.8
ENST00000398782.2
ribosome binding protein 1
chr1_+_40396766 3.68 ENST00000539317.2
small ArfGAP2
chr1_-_156751654 3.65 ENST00000357325.10
heparin binding growth factor
chr7_+_128241272 3.53 ENST00000308868.5
leptin
chr19_-_40465736 3.52 ENST00000263368.9
ENST00000595483.5
biliverdin reductase B
chr2_-_61018228 3.49 ENST00000316752.11
pseudouridine synthase 10
chr1_-_47231715 3.45 ENST00000371884.6
TAL bHLH transcription factor 1, erythroid differentiation factor
chr14_-_45253402 3.36 ENST00000627697.1
MIS18 binding protein 1
chr7_-_88306880 3.33 ENST00000414498.1
ENST00000301959.9
ENST00000380079.9
STEAP4 metalloreductase
chr8_-_6877928 3.23 ENST00000297439.4
defensin beta 1
chr20_-_3712564 3.23 ENST00000344754.6
sialic acid binding Ig like lectin 1
chr1_-_156751597 3.19 ENST00000537739.5
heparin binding growth factor
chr19_-_40465760 3.10 ENST00000643519.1
biliverdin reductase B
chr2_-_169031317 3.10 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr3_-_120682113 3.02 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr12_+_66189254 2.97 ENST00000457197.2
interleukin 1 receptor associated kinase 3
chr1_+_207088825 2.93 ENST00000367078.8
complement component 4 binding protein beta
chr17_+_7573722 2.93 ENST00000581384.5
ENST00000577929.1
eukaryotic translation initiation factor 4A1
chr1_+_154405573 2.92 ENST00000512471.1
interleukin 6 receptor
chr5_+_50666917 2.89 ENST00000514342.6
poly(ADP-ribose) polymerase family member 8
chr17_-_36090133 2.84 ENST00000613922.2
C-C motif chemokine ligand 3
chr19_-_40882226 2.84 ENST00000301146.9
cytochrome P450 family 2 subfamily A member 7
chr1_-_111200633 2.78 ENST00000357640.9
DENN domain containing 2D
chr19_+_50418930 2.77 ENST00000439922.6
ENST00000595883.6
ENST00000597855.5
ENST00000596074.5
ENST00000594685.1
ENST00000270632.7
Spi-B transcription factor
chr12_-_7109176 2.77 ENST00000545280.5
ENST00000543933.5
ENST00000545337.1
ENST00000266542.9
ENST00000544702.5
complement C1r subcomponent like
chr11_-_14972273 2.65 ENST00000396372.2
ENST00000361010.7
ENST00000331587.9
calcitonin related polypeptide alpha
chr3_+_16265160 2.64 ENST00000627468.2
ENST00000605932.5
ENST00000435829.6
ENST00000285083.10
oxidoreductase NAD binding domain containing 1
chr7_-_36724380 2.63 ENST00000617267.4
acyloxyacyl hydrolase
chr1_+_209768597 2.60 ENST00000487271.5
ENST00000477431.1
TRAF3 interacting protein 3
chr3_+_108822778 2.59 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr5_+_50666950 2.59 ENST00000513738.5
ENST00000503665.5
ENST00000514067.6
ENST00000503046.5
poly(ADP-ribose) polymerase family member 8
chr5_-_10761156 2.57 ENST00000432074.2
ENST00000230895.11
death associated protein
chr5_-_140633639 2.57 ENST00000498971.6
CD14 molecule
chr14_-_45253161 2.52 ENST00000451174.1
ENST00000310806.9
MIS18 binding protein 1
chr5_-_140633690 2.50 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr3_-_190862688 2.49 ENST00000442080.6
geminin coiled-coil domain containing
chr19_-_35528221 2.48 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr20_+_56412249 2.47 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr5_-_139383284 2.46 ENST00000353963.7
ENST00000348729.8
solute carrier family 23 member 1
chr12_+_66189208 2.43 ENST00000261233.9
interleukin 1 receptor associated kinase 3
chr19_-_6670151 2.43 ENST00000675206.1
TNF superfamily member 14
chr3_+_16265330 2.40 ENST00000606098.1
oxidoreductase NAD binding domain containing 1
chr1_-_67054100 2.35 ENST00000235345.6
solute carrier family 35 member D1
chr3_+_108822759 2.34 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr16_-_21652598 2.32 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr19_-_6670117 2.30 ENST00000245912.7
TNF superfamily member 14
chr22_+_39901075 2.29 ENST00000344138.9
GRB2 related adaptor protein 2
chr17_+_29043124 2.25 ENST00000323372.9
pipecolic acid and sarcosine oxidase
chr4_+_22692906 2.24 ENST00000613293.4
ENST00000610628.4
glucosylceramidase beta 3 (gene/pseudogene)
chr10_+_30434116 2.21 ENST00000415139.5
mitogen-activated protein kinase kinase kinase 8
chr22_+_17084920 2.19 ENST00000612619.1
ENST00000319363.11
interleukin 17 receptor A
chr3_+_133746385 2.19 ENST00000482271.5
ENST00000402696.9
transferrin
chr2_-_208254232 2.17 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr3_-_10505508 2.15 ENST00000643662.1
ENST00000397077.6
ENST00000360273.7
ATPase plasma membrane Ca2+ transporting 2
chr10_+_30434176 2.14 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr12_-_16277685 2.12 ENST00000344941.3
solute carrier family 15 member 5
chr14_+_20955484 2.12 ENST00000304625.3
ribonuclease A family member 2
chr17_-_79839387 2.11 ENST00000448310.1
ENST00000269397.9
chromobox 4
chr9_-_91423819 2.06 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr7_+_129144691 2.06 ENST00000486685.3
tetraspanin 33
chr5_-_140633656 2.05 ENST00000519715.1
CD14 molecule
chr9_+_107283137 2.05 ENST00000419616.5
RAD23 homolog B, nucleotide excision repair protein
chr10_+_30434602 1.98 ENST00000413724.5
mitogen-activated protein kinase kinase kinase 8
chr1_+_209768482 1.96 ENST00000367023.5
TRAF3 interacting protein 3
chr17_-_36196748 1.93 ENST00000619989.1
C-C motif chemokine ligand 3 like 1
chr20_+_56412393 1.77 ENST00000679529.1
Cas scaffold protein family member 4
chr12_+_103930600 1.76 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr9_+_107283256 1.76 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr20_+_841238 1.76 ENST00000541082.2
family with sequence similarity 110 member A
chr11_-_64742937 1.71 ENST00000394428.5
ENST00000394429.5
RAS guanyl releasing protein 2
chr2_-_68467272 1.69 ENST00000377957.4
F-box protein 48
chr11_+_94021346 1.68 ENST00000315765.10
hephaestin like 1
chrX_-_40647509 1.64 ENST00000378421.1
ENST00000378426.5
ENST00000327877.10
chromosome X open reading frame 38
chr1_-_154627576 1.62 ENST00000648311.1
adenosine deaminase RNA specific
chr20_-_1619996 1.60 ENST00000381603.7
ENST00000381605.9
ENST00000279477.11
ENST00000568365.1
ENST00000564763.1
signal regulatory protein beta 1
novel protein, SIRPB1-SIRPD readthrough
chr15_+_81000913 1.59 ENST00000267984.4
talin rod domain containing 1
chr8_+_8701891 1.57 ENST00000519106.2
claudin 23
chr2_-_101308681 1.55 ENST00000295317.4
ring finger protein 149
chr1_-_151059561 1.52 ENST00000357235.6
ENST00000540998.5
CDC42 small effector 1
chr1_+_162561504 1.51 ENST00000271469.7
ENST00000367926.8
UDP-N-acetylglucosamine pyrophosphorylase 1
chr7_+_150368189 1.50 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr19_-_51645545 1.49 ENST00000534261.3
sialic acid binding Ig like lectin 5
chr4_-_185811088 1.49 ENST00000421639.5
sorbin and SH3 domain containing 2
chr12_+_66189178 1.48 ENST00000545837.1
interleukin 1 receptor associated kinase 3
chr14_+_51847145 1.44 ENST00000615906.4
G protein subunit gamma 2
chr14_+_51847116 1.42 ENST00000553560.5
G protein subunit gamma 2
chr11_+_83156988 1.42 ENST00000298281.8
ENST00000530660.5
PCF11 cleavage and polyadenylation factor subunit
chr10_-_95656643 1.40 ENST00000371221.3
ENST00000371224.7
aldehyde dehydrogenase 18 family member A1
chr9_-_127950716 1.37 ENST00000373084.8
family with sequence similarity 102 member A
chr19_-_6720641 1.31 ENST00000245907.11
complement C3
chr20_-_45254556 1.30 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr12_-_88029385 1.27 ENST00000298699.7
ENST00000550553.5
chromosome 12 open reading frame 50
chr3_-_151384741 1.23 ENST00000302632.4
purinergic receptor P2Y12
chr1_+_222737283 1.21 ENST00000360827.6
family with sequence similarity 177 member B
chr20_-_59007807 1.16 ENST00000680386.1
cathepsin Z
chr11_+_83157143 1.16 ENST00000530304.5
ENST00000533018.1
PCF11 cleavage and polyadenylation factor subunit
chr3_+_136930469 1.15 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr14_+_103121457 1.14 ENST00000333007.8
TNF alpha induced protein 2
chr11_-_105035113 1.11 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr1_-_54801290 1.10 ENST00000371276.9
tetratricopeptide repeat domain 22
chr7_-_141702151 1.08 ENST00000536163.6
DENN domain containing 11
chr14_+_67241627 1.07 ENST00000557237.1
membrane palmitoylated protein 5
chr1_-_154608705 1.07 ENST00000649749.1
ENST00000648871.1
adenosine deaminase RNA specific
chr10_+_88990531 1.06 ENST00000355740.7
Fas cell surface death receptor
chr19_+_1030819 1.05 ENST00000566695.5
calponin 2
chr2_-_46542555 1.03 ENST00000522587.6
ATPase H+ transporting V1 subunit E2
chr9_+_92964272 1.02 ENST00000468206.6
FYVE, RhoGEF and PH domain containing 3
chr15_-_82952683 1.01 ENST00000450735.7
ENST00000304231.12
homer scaffold protein 2
chr2_+_183124428 1.01 ENST00000295119.9
nucleoporin 35
chr4_-_112285892 1.00 ENST00000361717.4
TRAF interacting protein with forkhead associated domain
chr22_-_20377251 1.00 ENST00000292729.12
ubiquitin specific peptidase 41
chr1_+_32292067 0.99 ENST00000373548.8
ENST00000428704.1
histone deacetylase 1
chr1_+_93179883 0.98 ENST00000343253.11
coiled-coil domain containing 18
chr20_+_56412112 0.97 ENST00000360314.7
Cas scaffold protein family member 4
chr19_+_48445961 0.96 ENST00000253237.10
glutamate rich WD repeat containing 1
chr1_-_92486049 0.96 ENST00000427103.5
growth factor independent 1 transcriptional repressor
chr3_+_11272413 0.95 ENST00000446450.6
ENST00000354956.9
ENST00000354449.7
ENST00000419112.5
autophagy related 7
chr10_+_88990621 0.95 ENST00000352159.8
Fas cell surface death receptor
chr11_-_102724945 0.95 ENST00000236826.8
matrix metallopeptidase 8
chr10_-_102837406 0.91 ENST00000369887.4
ENST00000638272.1
ENST00000639393.1
ENST00000638971.1
ENST00000638190.1
cytochrome P450 family 17 subfamily A member 1
chr10_+_75431605 0.90 ENST00000611255.5
leucine rich melanocyte differentiation associated
chr1_+_161118083 0.88 ENST00000368009.7
ENST00000368007.8
ENST00000392190.9
ENST00000368008.5
nitrilase 1
chr21_-_30561314 0.86 ENST00000334849.2
keratin associated protein 19-7
chr10_-_97270638 0.84 ENST00000371027.5
Rho GTPase activating protein 19
chr12_-_52680398 0.80 ENST00000252244.3
keratin 1
chr4_+_70518563 0.79 ENST00000339336.9
amelotin
chr7_+_90403506 0.75 ENST00000427904.1
claudin 12
chr10_+_88990736 0.73 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPE_CEBPD

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.4 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
5.7 28.7 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
5.0 20.0 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
4.3 29.9 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
4.0 16.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
3.4 13.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
2.3 7.0 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
2.3 11.6 GO:0002384 hepatic immune response(GO:0002384)
2.3 6.9 GO:0010933 macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933)
2.3 9.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
2.0 19.7 GO:0000821 regulation of arginine metabolic process(GO:0000821)
1.9 13.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.8 18.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
1.7 5.2 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
1.6 4.8 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
1.6 4.8 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.6 22.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.4 11.4 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.4 5.7 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.3 4.0 GO:0046110 xanthine metabolic process(GO:0046110)
1.3 5.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
1.3 8.9 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.2 4.7 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.2 8.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.2 3.5 GO:0030221 basophil differentiation(GO:0030221)
1.1 13.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.1 2.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.1 18.2 GO:0015939 pantothenate metabolic process(GO:0015939)
1.0 3.9 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.9 4.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.9 77.5 GO:0006953 acute-phase response(GO:0006953)
0.9 4.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.9 2.7 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.8 2.5 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.8 3.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.7 2.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.7 7.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.7 4.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.7 4.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 9.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 3.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6 5.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.6 1.8 GO:0031247 actin rod assembly(GO:0031247)
0.6 3.9 GO:0072526 inosine metabolic process(GO:0046102) pyridine-containing compound catabolic process(GO:0072526)
0.5 1.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.5 6.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 3.3 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 2.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.5 1.4 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.5 2.7 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.5 5.4 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4 2.7 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.4 11.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 2.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.4 8.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.4 1.2 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.4 2.3 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.4 1.1 GO:0050717 regulation of interleukin-1 alpha secretion(GO:0050705) positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 10.3 GO:0006825 copper ion transport(GO:0006825)
0.3 2.9 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 1.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.3 2.9 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.3 6.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 13.8 GO:0050832 defense response to fungus(GO:0050832)
0.3 3.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.3 1.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.3 5.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.3 10.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 5.6 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.2 2.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.2 1.1 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 0.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.2 0.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 1.2 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 15.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 1.4 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.2 7.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 6.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.5 GO:1903611 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.1 0.5 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.1 0.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 1.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 1.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 3.8 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 2.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.0 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 6.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 0.2 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 2.6 GO:0006379 mRNA cleavage(GO:0006379)
0.1 6.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.0 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.9 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 1.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 2.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 1.0 GO:0006999 nuclear pore organization(GO:0006999)
0.0 1.9 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 1.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 5.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.3 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 2.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 2.1 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 2.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.1 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
2.0 15.6 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
1.2 64.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
1.0 11.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.7 5.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.7 5.8 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.7 8.5 GO:0005577 fibrinogen complex(GO:0005577)
0.6 3.2 GO:1990742 microvesicle(GO:1990742)
0.5 3.8 GO:0071942 XPC complex(GO:0071942)
0.4 2.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.4 15.5 GO:0036019 endolysosome(GO:0036019)
0.4 5.9 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.3 2.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 28.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 1.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 3.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 17.1 GO:0035580 specific granule lumen(GO:0035580)
0.2 4.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 2.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.1 GO:0043219 lateral loop(GO:0043219)
0.1 1.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 2.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 56.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 13.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 20.0 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 2.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 10.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 1.0 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 14.2 GO:0072562 blood microparticle(GO:0072562)
0.1 7.2 GO:0043195 terminal bouton(GO:0043195)
0.1 1.0 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 8.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 5.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 5.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.3 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.0 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 7.0 GO:0043204 perikaryon(GO:0043204)
0.0 2.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 6.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 51.3 GO:0005615 extracellular space(GO:0005615)
0.0 2.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.0 GO:0043596 nuclear replication fork(GO:0043596)
0.0 3.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 28.7 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
4.7 18.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
4.3 29.9 GO:0016841 ammonia-lyase activity(GO:0016841)
4.0 28.3 GO:0030492 hemoglobin binding(GO:0030492)
3.9 15.6 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
2.7 8.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
2.4 7.2 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
2.2 8.9 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
2.0 15.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.9 5.6 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.8 7.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.4 11.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.4 5.4 GO:0004074 biliverdin reductase activity(GO:0004074)
1.2 63.5 GO:0042056 chemoattractant activity(GO:0042056)
1.1 7.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.0 3.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
1.0 3.9 GO:0002060 purine nucleobase binding(GO:0002060)
1.0 9.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.9 15.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.9 2.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.8 2.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.8 19.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.8 3.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.8 4.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.8 5.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.7 2.2 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.7 2.7 GO:0031716 calcitonin receptor binding(GO:0031716)
0.7 4.0 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.6 3.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.6 13.6 GO:0019841 retinol binding(GO:0019841)
0.6 12.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.6 3.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 5.8 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.5 15.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 1.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.5 13.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.5 2.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.4 2.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.4 4.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.4 1.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.4 2.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 2.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 0.7 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 2.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.3 1.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 13.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 6.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 25.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 2.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 2.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 1.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 3.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 4.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.0 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 2.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 2.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 6.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 13.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.5 GO:0004341 gluconolactonase activity(GO:0004341)
0.1 2.6 GO:0070513 death domain binding(GO:0070513)
0.1 0.5 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 42.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0070052 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.1 0.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 4.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 7.8 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 2.9 GO:0000339 RNA cap binding(GO:0000339)
0.1 2.1 GO:0032183 SUMO binding(GO:0032183)
0.1 1.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 3.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.0 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 1.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 8.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 3.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 5.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 3.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 4.8 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 4.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 31.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 11.6 ST STAT3 PATHWAY STAT3 Pathway
0.4 25.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 8.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 16.5 PID BMP PATHWAY BMP receptor signaling
0.2 13.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 15.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 10.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 33.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 8.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 8.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 28.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.2 33.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.1 29.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 20.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 11.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.6 10.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.6 11.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.5 9.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.5 7.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 13.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.4 7.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 5.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 4.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 13.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 12.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 19.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.3 9.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 14.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 5.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 5.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 46.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 3.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 3.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 5.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 4.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 2.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 4.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 2.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 4.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 6.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 14.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 5.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 7.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.7 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.2 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 2.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity