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Illumina Body Map 2 (GSE30611)

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Results for CENPB

Z-value: 0.71

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Transcription factors associated with CENPB

Gene Symbol Gene ID Gene Info
ENSG00000125817.8 centromere protein B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CENPBhg38_v1_chr20_-_3786677_3786797-0.281.2e-01Click!

Activity profile of CENPB motif

Sorted Z-values of CENPB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_34795541 1.69 ENST00000290378.6
actin alpha cardiac muscle 1
chr16_+_56669807 1.59 ENST00000332374.5
metallothionein 1H
chr16_+_66934439 1.37 ENST00000417689.6
ENST00000561697.5
carboxylesterase 2
chrX_-_21658324 1.29 ENST00000379499.3
kelch like family member 34
chr3_-_142963663 1.28 ENST00000340634.6
progestin and adipoQ receptor family member 9
chr16_+_56669832 1.25 ENST00000569155.1
metallothionein 1H
chr1_-_18902520 0.99 ENST00000538839.5
ENST00000290597.9
ENST00000375341.8
aldehyde dehydrogenase 4 family member A1
chr17_-_48722510 0.99 ENST00000290294.5
PRAC1 small nuclear protein
chr6_-_105179952 0.99 ENST00000254765.4
popeye domain containing 3
chr14_-_50312212 0.96 ENST00000555423.5
ENST00000267436.9
ENST00000421284.7
L-2-hydroxyglutarate dehydrogenase
chr14_-_50312154 0.93 ENST00000555610.1
ENST00000261699.8
L-2-hydroxyglutarate dehydrogenase
chr19_-_48363914 0.91 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chr16_-_81096163 0.90 ENST00000566566.2
ENST00000569885.6
ENST00000561801.2
ENST00000639689.1
ENST00000638948.1
ENST00000564536.2
ENST00000638192.1
ENST00000640345.1
glycine cleavage system protein H
novel protein
novel protein
chr1_-_18902724 0.90 ENST00000432718.1
aldehyde dehydrogenase 4 family member A1
chr2_+_102736903 0.89 ENST00000639249.1
ENST00000454536.5
ENST00000409528.5
ENST00000409173.5
ENST00000488134.5
transmembrane protein 182
chr19_-_48364034 0.81 ENST00000435956.7
transmembrane protein 143
chr17_+_36942198 0.80 ENST00000621767.1
LIM homeobox 1
chr3_+_131381671 0.77 ENST00000537561.5
ENST00000521288.2
ENST00000502852.1
nudix hydrolase 16
chr3_-_122383218 0.74 ENST00000479899.5
ENST00000291458.9
ENST00000497726.5
mitochondrial matrix import factor 23
chr11_+_126283059 0.73 ENST00000392679.6
ENST00000392678.7
ENST00000392680.6
TIR domain containing adaptor protein
chr20_-_57266342 0.71 ENST00000395864.7
bone morphogenetic protein 7
chr19_-_40714641 0.70 ENST00000678467.1
coenzyme Q8B
chr6_+_26124161 0.70 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr3_+_52198086 0.67 ENST00000469224.5
ENST00000394965.6
5'-aminolevulinate synthase 1
chr19_-_45493208 0.66 ENST00000430715.6
reticulon 2
chr18_-_56651122 0.65 ENST00000590954.5
thioredoxin like 1
chr8_-_23706756 0.65 ENST00000325017.4
NK2 homeobox 6
chr1_-_167935987 0.65 ENST00000367846.8
mitochondrial pyruvate carrier 2
chr1_+_212791828 0.56 ENST00000532324.5
ENST00000530441.5
ENST00000526641.5
ENST00000531963.5
ENST00000366973.8
ENST00000366974.9
ENST00000526997.5
ENST00000488246.6
TatD DNase domain containing 3
chr9_+_706841 0.56 ENST00000382293.7
KN motif and ankyrin repeat domains 1
chr15_+_67823557 0.56 ENST00000554240.5
SKI family transcriptional corepressor 1
chr19_+_41376692 0.55 ENST00000447302.6
ENST00000544232.5
ENST00000542945.5
ENST00000540732.3
transmembrane protein 91
novel protein
chr19_-_16472003 0.54 ENST00000248070.10
ENST00000594975.5
epidermal growth factor receptor pathway substrate 15 like 1
chr20_-_54173976 0.53 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr5_-_59768631 0.52 ENST00000502575.1
ENST00000507116.5
phosphodiesterase 4D
chr14_+_50312311 0.52 ENST00000426751.7
ENST00000311459.12
ENST00000672419.1
ENST00000672910.1
ENST00000557421.7
ENST00000245448.11
ENST00000554204.7
distal membrane arm assembly complex 2 like
chr6_-_26123910 0.51 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr8_+_27311620 0.48 ENST00000522338.5
protein tyrosine kinase 2 beta
chr17_+_74431338 0.48 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chr16_-_81096336 0.48 ENST00000639169.1
ENST00000315467.9
glycine cleavage system protein H
chr12_-_110468222 0.47 ENST00000228827.8
ENST00000537466.6
ENST00000550974.1
GPN-loop GTPase 3
chr3_+_57890011 0.47 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr15_+_49155750 0.46 ENST00000327171.7
ENST00000560654.5
galactokinase 2
chr19_-_16471943 0.46 ENST00000602151.1
ENST00000597937.5
ENST00000455140.7
ENST00000535753.6
epidermal growth factor receptor pathway substrate 15 like 1
chr17_-_28902930 0.45 ENST00000426464.2
dehydrogenase/reductase 13
chr1_+_151399557 0.45 ENST00000290541.7
proteasome 20S subunit beta 4
chr10_+_22316445 0.44 ENST00000448361.5
COMM domain containing 3
chr20_+_21303303 0.42 ENST00000377191.5
5'-3' exoribonuclease 2
chr3_-_42804429 0.42 ENST00000452906.3
HIG1 hypoxia inducible domain family member 1A
chr4_-_113761563 0.42 ENST00000394522.7
calcium/calmodulin dependent protein kinase II delta
chr11_-_82901507 0.40 ENST00000533126.1
prolylcarboxypeptidase
chr11_+_59755398 0.39 ENST00000633708.1
syntaxin 3
chr15_+_90184912 0.39 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr9_-_136205122 0.38 ENST00000371748.10
LIM homeobox 3
chr7_+_983175 0.38 ENST00000308919.12
cytochrome P450 family 2 subfamily W member 1
chr4_+_6909444 0.38 ENST00000448507.5
TBC1 domain family member 14
chr20_+_5126886 0.37 ENST00000450570.1
CDP-diacylglycerol synthase 2
chr10_+_38010617 0.37 ENST00000307441.13
ENST00000374618.7
ENST00000628825.2
ENST00000458705.6
ENST00000432900.7
ENST00000469037.2
zinc finger protein 33A
chr1_-_28176665 0.35 ENST00000373857.8
platelet activating factor receptor
chr4_-_83010709 0.35 ENST00000506560.5
ENST00000442461.6
ENST00000340417.8
ENST00000446851.6
lin-54 DREAM MuvB core complex component
chr7_-_128409946 0.34 ENST00000489263.1
inosine monophosphate dehydrogenase 1
chr19_+_11965029 0.34 ENST00000592625.5
ENST00000358987.8
ENST00000586494.1
ENST00000343949.9
zinc finger protein 763
chr8_-_143609547 0.34 ENST00000433751.5
ENST00000495276.6
ENST00000220966.10
pyrroline-5-carboxylate reductase 3
chr3_+_149813806 0.33 ENST00000468648.5
ENST00000459632.5
ring finger protein 13
chr5_+_72816643 0.33 ENST00000337273.10
ENST00000523768.5
transportin 1
chr9_-_120580125 0.33 ENST00000360190.8
ENST00000349780.9
ENST00000360822.7
CDK5 regulatory subunit associated protein 2
chr15_-_43330537 0.33 ENST00000305641.7
ENST00000567039.1
leucine carboxyl methyltransferase 2
chr10_+_129467178 0.33 ENST00000306010.8
ENST00000651593.1
O-6-methylguanine-DNA methyltransferase
chr19_+_51927435 0.32 ENST00000391794.8
ENST00000599683.5
ENST00000293471.11
ENST00000600853.1
zinc finger protein 613
chr10_+_22316375 0.32 ENST00000376836.8
ENST00000456711.5
ENST00000444869.5
ENST00000475460.6
ENST00000602390.5
ENST00000489125.2
COMM domain containing 3
COMMD3-BMI1 readthrough
chr11_-_119057185 0.32 ENST00000614668.4
ENST00000617285.5
hypoxia up-regulated 1
chr5_-_151087660 0.31 ENST00000522226.5
TNFAIP3 interacting protein 1
chr11_+_59755427 0.31 ENST00000529177.5
syntaxin 3
chr20_-_57266606 0.31 ENST00000450594.6
ENST00000395863.8
bone morphogenetic protein 7
chr16_-_66934144 0.31 ENST00000568572.5
cytosolic iron-sulfur assembly component 2B
chr15_+_45587336 0.30 ENST00000564080.1
ENST00000562384.5
ENST00000569076.5
novel protein
biogenesis of lysosomal organelles complex 1 subunit 6
chr3_+_147393718 0.29 ENST00000488404.5
Zic family member 1
chr4_-_164383986 0.29 ENST00000507270.5
ENST00000514618.5
ENST00000503008.5
membrane associated ring-CH-type finger 1
chr7_+_50308672 0.29 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKAROS family zinc finger 1
chr3_-_42804451 0.28 ENST00000418900.6
ENST00000321331.12
ENST00000430190.5
ENST00000648550.1
HIG1 hypoxia inducible domain family member 1A
novel protein
chr9_+_101028721 0.28 ENST00000374874.8
phospholipid phosphatase related 1
chr5_+_151447576 0.28 ENST00000243389.8
ENST00000616007.4
ENST00000517945.5
ENST00000521925.5
solute carrier family 36 member 1
chr13_-_41061373 0.28 ENST00000405737.2
E74 like ETS transcription factor 1
chr11_-_62546826 0.27 ENST00000531324.1
AHNAK nucleoprotein
chr6_-_166168700 0.27 ENST00000366871.7
T-box transcription factor T
chr11_-_119057218 0.27 ENST00000652093.1
hypoxia up-regulated 1
chr6_-_166168645 0.27 ENST00000461348.2
T-box transcription factor T
chr16_-_30558263 0.27 ENST00000252797.6
zinc finger protein 764
chr16_-_30558356 0.26 ENST00000395091.3
zinc finger protein 764
chr18_+_33578213 0.26 ENST00000681521.1
ENST00000269197.12
ASXL transcriptional regulator 3
chr6_-_166168612 0.26 ENST00000296946.6
T-box transcription factor T
chr16_-_87936529 0.26 ENST00000649794.3
ENST00000649158.1
ENST00000648177.1
carbonic anhydrase 5A
chr3_+_38138478 0.26 ENST00000396334.8
ENST00000417037.8
ENST00000652213.1
ENST00000650112.2
ENST00000651800.2
ENST00000421516.3
ENST00000650905.2
MYD88 innate immune signal transduction adaptor
chr3_-_142448060 0.26 ENST00000264951.8
5'-3' exoribonuclease 1
chr18_+_56651335 0.26 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chrX_-_136880715 0.26 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr11_-_119057169 0.25 ENST00000527038.6
hypoxia up-regulated 1
chr11_-_119057024 0.25 ENST00000526656.5
hypoxia up-regulated 1
chr11_+_61430036 0.25 ENST00000541135.5
novel transcript
chr11_-_119057105 0.25 ENST00000534233.5
ENST00000614711.4
ENST00000530467.5
ENST00000621959.4
ENST00000532519.6
ENST00000532421.5
ENST00000610597.1
ENST00000612687.4
hypoxia up-regulated 1
chr3_+_149813049 0.24 ENST00000466478.5
ENST00000491086.5
ENST00000467977.5
ENST00000392894.8
ring finger protein 13
chr16_-_11636357 0.24 ENST00000576334.1
ENST00000574848.5
lipopolysaccharide induced TNF factor
chr9_-_37025733 0.24 ENST00000651550.1
paired box 5
chr3_-_142448028 0.24 ENST00000392981.7
5'-3' exoribonuclease 1
chr6_+_24667026 0.24 ENST00000537591.5
ENST00000230048.5
acyl-CoA thioesterase 13
chr1_+_11664191 0.23 ENST00000376753.9
F-box protein 6
chr7_+_100706061 0.23 ENST00000303151.5
POP7 homolog, ribonuclease P/MRP subunit
chr6_-_166587594 0.23 ENST00000444122.2
RNA guanine-7 methyltransferase activating subunit like (pseudogene)
chr1_-_51345105 0.22 ENST00000413473.6
ENST00000401051.7
ENST00000527205.1
tetratricopeptide repeat domain 39A
chr22_+_18633984 0.22 ENST00000652395.1
family with sequence similarity 246 member B
chr5_+_81301634 0.22 ENST00000438268.2
zinc finger CCHC-type containing 9
chr11_+_61430100 0.22 ENST00000542074.1
ENST00000534878.5
ENST00000301761.7
ENST00000537782.5
ENST00000543265.1
succinate dehydrogenase complex assembly factor 2
chr6_-_46652786 0.22 ENST00000275016.3
ENST00000619708.4
cytochrome P450 family 39 subfamily A member 1
chr4_-_113761441 0.22 ENST00000394524.7
calcium/calmodulin dependent protein kinase II delta
chr16_-_66934362 0.22 ENST00000567511.1
ENST00000422424.7
cytosolic iron-sulfur assembly component 2B
chrX_-_136880754 0.21 ENST00000565438.1
RNA binding motif protein X-linked
chr7_+_2354078 0.21 ENST00000431643.5
eukaryotic translation initiation factor 3 subunit B
chr11_-_119056850 0.20 ENST00000530473.5
hypoxia up-regulated 1
chr5_+_81301570 0.20 ENST00000407610.8
ENST00000254037.6
ENST00000380199.9
zinc finger CCHC-type containing 9
chr1_+_7961894 0.19 ENST00000377491.5
ENST00000377488.5
Parkinsonism associated deglycase
chr5_+_137889437 0.19 ENST00000508638.5
ENST00000508883.6
ENST00000502810.5
polycystin 2 like 2, transient receptor potential cation channel
chr1_-_7940825 0.18 ENST00000377507.8
TNF receptor superfamily member 9
chr3_+_15427551 0.18 ENST00000396842.7
ELL associated factor 1
chr10_+_1056776 0.18 ENST00000650072.1
WD repeat domain 37
chr2_+_73202570 0.18 ENST00000398468.4
notochord homeobox
chr6_-_24666591 0.18 ENST00000341060.3
tyrosyl-DNA phosphodiesterase 2
chr1_+_155323473 0.17 ENST00000497930.5
RUN and SH3 domain containing 1
chr11_-_72244166 0.17 ENST00000298231.5
paired like homeobox 2A
chr20_+_5126988 0.17 ENST00000460006.6
CDP-diacylglycerol synthase 2
chr3_+_173398438 0.17 ENST00000457714.5
neuroligin 1
chr1_-_6235945 0.15 ENST00000343813.10
isoprenylcysteine carboxyl methyltransferase
chr20_+_408030 0.15 ENST00000640614.1
ENST00000475269.5
RANBP2-type and C3HC4-type zinc finger containing 1
chr19_+_36100593 0.15 ENST00000680211.1
WD repeat domain 62
chr20_+_408147 0.14 ENST00000441733.5
ENST00000353660.7
RANBP2-type and C3HC4-type zinc finger containing 1
chr19_-_5719849 0.14 ENST00000590729.5
lon peptidase 1, mitochondrial
chr15_-_55588337 0.14 ENST00000563719.4
pygopus family PHD finger 1
chr8_-_144336451 0.14 ENST00000569446.3
scratch family transcriptional repressor 1
chr10_-_87818153 0.14 ENST00000308448.11
ENST00000680024.1
ATPase family AAA domain containing 1
chr19_+_41376560 0.14 ENST00000436170.6
transmembrane protein 91
chr1_-_151346806 0.13 ENST00000392746.7
regulatory factor X5
chr1_-_221742074 0.13 ENST00000366899.4
dual specificity phosphatase 10
chr17_+_31487995 0.13 ENST00000394744.6
RAB11 family interacting protein 4
chr3_-_15427497 0.12 ENST00000443029.5
ENST00000383789.9
ENST00000450816.6
ENST00000383790.8
methyltransferase like 6
chr18_+_56651385 0.12 ENST00000615645.4
WD repeat domain 7
chr3_+_26622800 0.12 ENST00000396641.6
leucine rich repeat containing 3B
chr5_+_139795795 0.12 ENST00000274710.4
pleckstrin and Sec7 domain containing 2
chr6_+_4772971 0.12 ENST00000440139.5
chromodomain Y like
chr1_-_151347178 0.11 ENST00000430227.5
ENST00000412774.5
regulatory factor X5
chr4_-_169757873 0.10 ENST00000393381.3
histone PARylation factor 1
chr6_-_109382397 0.10 ENST00000512821.5
CD164 molecule
chr1_-_113812448 0.10 ENST00000612242.4
ENST00000261441.9
round spermatid basic protein 1
chr19_+_11848717 0.09 ENST00000682736.1
zinc finger protein 439
chr18_-_268019 0.09 ENST00000631280.2
ENST00000616322.4
ENST00000261600.11
THO complex 1
chr15_-_49155574 0.09 ENST00000558843.5
ENST00000388901.10
ENST00000542928.5
ENST00000561248.1
ENST00000299259.10
COP9 signalosome subunit 2
chrX_-_119791620 0.09 ENST00000361575.4
ribosomal protein L39
chr2_+_74513441 0.09 ENST00000621092.1
T cell leukemia homeobox 2
chr19_-_14090695 0.07 ENST00000533683.7
sterile alpha motif domain containing 1
chr19_+_11848740 0.07 ENST00000455282.1
zinc finger protein 439
chr9_+_32552305 0.07 ENST00000451672.2
ENST00000644531.1
small integral membrane protein 27
chrX_-_140505058 0.07 ENST00000370536.5
SRY-box transcription factor 3
chr11_+_58579052 0.06 ENST00000316059.7
ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
chr16_+_569931 0.06 ENST00000439574.1
ENST00000321878.10
ENST00000422307.6
ENST00000026218.9
ENST00000470411.2
phosphatidylinositol glycan anchor biosynthesis class Q
chr18_+_56651661 0.06 ENST00000593058.1
WD repeat domain 7
chr4_-_81214960 0.06 ENST00000395578.3
ENST00000628926.1
protein kinase cGMP-dependent 2
chr1_-_64966284 0.06 ENST00000671929.1
ENST00000673046.1
ENST00000672247.1
Janus kinase 1
chr13_+_48233171 0.06 ENST00000378549.5
ENST00000647800.2
integral membrane protein 2B
chr2_-_102736819 0.06 ENST00000258436.10
major facilitator superfamily domain containing 9
chr3_+_182793478 0.06 ENST00000493826.1
ENST00000323116.10
ATPase phospholipid transporting 11B (putative)
chr8_-_27311220 0.06 ENST00000521253.1
ENST00000305364.9
tripartite motif containing 35
chr6_-_24666854 0.05 ENST00000378198.9
tyrosyl-DNA phosphodiesterase 2
chr14_-_100306430 0.05 ENST00000392908.7
ENST00000359232.8
solute carrier family 25 member 29
chr6_-_28443463 0.05 ENST00000289788.4
zinc finger and SCAN domain containing 23
chr19_+_41376499 0.05 ENST00000392002.7
transmembrane protein 91
chr1_-_151346846 0.04 ENST00000436271.5
ENST00000450506.5
ENST00000422595.5
regulatory factor X5
chr11_+_59755365 0.03 ENST00000337979.9
syntaxin 3
chr13_+_23579346 0.03 ENST00000382258.8
ENST00000382263.3
TNF receptor superfamily member 19
chr1_-_151347234 0.03 ENST00000290524.8
ENST00000452671.7
ENST00000437327.5
ENST00000368870.6
regulatory factor X5
chr4_-_169612571 0.03 ENST00000507142.6
ENST00000510533.5
ENST00000439128.6
ENST00000511633.5
ENST00000512193.5
NIMA related kinase 1
chr5_+_137889469 0.03 ENST00000290431.5
polycystin 2 like 2, transient receptor potential cation channel
chr20_-_43189896 0.03 ENST00000373193.7
ENST00000373198.8
ENST00000373201.5
protein tyrosine phosphatase receptor type T
chr2_+_206275002 0.02 ENST00000650097.1
ENST00000649525.1
ENST00000649998.1
zinc finger DBF-type containing 2
chr9_+_135479655 0.02 ENST00000604351.5
protein phosphatase 1 regulatory subunit 26
chr17_-_7043906 0.01 ENST00000308009.5
ENST00000447225.1
solute carrier family 16 member 11
chr8_-_55773295 0.01 ENST00000523423.5
ENST00000523073.5
ENST00000519784.5
ENST00000519780.5
ENST00000521229.5
ENST00000434581.7
ENST00000522576.5
ENST00000523180.5
ENST00000522090.5
transmembrane protein 68
chr15_+_45587230 0.00 ENST00000567461.5
biogenesis of lysosomal organelles complex 1 subunit 6
chr20_-_43189733 0.00 ENST00000373187.5
ENST00000356100.6
ENST00000373184.5
ENST00000373190.5
protein tyrosine phosphatase receptor type T
chr6_-_109382460 0.00 ENST00000310786.10
CD164 molecule
chr4_+_56436233 0.00 ENST00000512576.3
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

Network of associatons between targets according to the STRING database.

First level regulatory network of CENPB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.7 GO:0090131 mesenchyme migration(GO:0090131)
0.3 0.8 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.3 0.8 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.3 1.0 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069)
0.2 1.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 1.5 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1 0.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.6 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.5 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.5 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 2.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.6 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.3 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.5 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.7 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.2 GO:1903181 detoxification of copper ion(GO:0010273) enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) stress response to copper ion(GO:1990169) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 1.9 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.2 GO:0097032 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.4 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.2 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.6 GO:1901725 regulation of histone deacetylase activity(GO:1901725) regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.7 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0089709 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 1.4 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0042643 actomyosin, actin portion(GO:0042643)
0.3 1.4 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.7 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.3 1.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 0.7 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 0.8 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 0.5 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.9 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.5 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.7 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.5 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.4 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 2.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.3 GO:0022858 hydrogen:amino acid symporter activity(GO:0005280) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.9 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis