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Illumina Body Map 2 (GSE30611)

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Results for CREB5_CREM_JUNB

Z-value: 2.12

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
ENSG00000146592.17 cAMP responsive element binding protein 5
ENSG00000095794.19 cAMP responsive element modulator
ENSG00000171223.6 JunB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB5hg38_v1_chr7_+_28409344_284093920.522.1e-03Click!
JUNBhg38_v1_chr19_+_12791470_12791494-0.441.2e-02Click!
CREMhg38_v1_chr10_+_35195124_351951480.431.4e-02Click!

Activity profile of CREB5_CREM_JUNB motif

Sorted Z-values of CREB5_CREM_JUNB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_43862480 27.14 ENST00000330884.9
sulfotransferase family 4A member 1
chr20_+_34558706 20.15 ENST00000360668.8
ENST00000397709.1
microtubule associated protein 1 light chain 3 alpha
chr11_+_12674397 15.51 ENST00000527636.7
TEA domain transcription factor 1
chr20_+_5911501 13.07 ENST00000378961.9
ENST00000455042.1
chromogranin B
chr14_-_103522696 12.00 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr2_-_223602284 11.76 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr8_-_27258386 11.60 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chr7_+_30134956 11.34 ENST00000324453.13
ENST00000409688.1
maturin, neural progenitor differentiation regulator homolog
chr20_+_17227020 10.96 ENST00000262545.7
ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr6_-_127459364 10.51 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr20_+_10218808 10.48 ENST00000254976.7
ENST00000304886.6
synaptosome associated protein 25
chr4_-_185535498 10.11 ENST00000284767.12
ENST00000284771.7
ENST00000284770.10
ENST00000620787.5
ENST00000629667.2
PDZ and LIM domain 3
chrX_-_13938618 9.90 ENST00000454189.6
glycoprotein M6B
chr6_-_46325641 9.41 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chr2_+_148875214 9.32 ENST00000435030.6
ENST00000677891.1
ENST00000677843.1
ENST00000678056.1
ENST00000677280.1
kinesin family member 5C
chr19_+_18612848 9.02 ENST00000262817.8
transmembrane protein 59 like
chr20_-_3173516 8.98 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
leucine zipper tumor suppressor family member 3
chr16_+_29900474 8.55 ENST00000308748.10
aspartate beta-hydroxylase domain containing 1
chr11_+_66291887 8.41 ENST00000327259.5
transmembrane protein 151A
chr2_-_240820205 8.31 ENST00000647731.1
ENST00000648680.1
ENST00000649306.1
ENST00000648129.1
ENST00000498729.9
ENST00000320389.12
ENST00000648364.1
ENST00000647885.1
ENST00000404283.9
ENST00000649096.1
kinesin family member 1A
chr14_+_92923143 8.20 ENST00000216492.10
ENST00000334654.4
chromogranin A
chr11_-_1572261 7.97 ENST00000397374.8
dual specificity phosphatase 8
chrX_-_13938378 7.78 ENST00000398361.7
glycoprotein M6B
chrX_+_153687918 7.58 ENST00000253122.10
solute carrier family 6 member 8
chrX_-_47619850 7.58 ENST00000295987.13
ENST00000340666.5
synapsin I
chr13_-_28495079 7.42 ENST00000615840.4
ENST00000282397.9
ENST00000541932.5
ENST00000539099.1
ENST00000639477.1
fms related receptor tyrosine kinase 1
chr20_+_10218948 7.39 ENST00000430336.1
synaptosome associated protein 25
chr11_-_119317119 7.30 ENST00000264036.6
melanoma cell adhesion molecule
chr16_+_56191728 7.28 ENST00000638705.1
ENST00000262494.12
G protein subunit alpha o1
chr6_+_56955097 7.19 ENST00000370746.8
ENST00000370748.7
BEN domain containing 6
chr2_-_215436061 6.87 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr19_-_56840661 6.74 ENST00000649735.1
ENST00000593695.5
ENST00000599577.5
ENST00000594389.1
ENST00000648694.1
ENST00000326441.15
ENST00000649680.1
ENST00000649876.1
ENST00000650632.1
ENST00000650102.1
ENST00000647621.1
ENST00000598410.5
ENST00000649233.1
ENST00000593711.6
ENST00000629319.2
ENST00000599935.5
paternally expressed 3
zinc finger imprinted 2
chr8_-_27258414 6.66 ENST00000523048.5
stathmin 4
chr6_-_3157536 6.51 ENST00000333628.4
tubulin beta 2A class IIa
chr7_-_45088888 6.45 ENST00000490531.3
NAC alpha domain containing
chr17_+_44308573 6.35 ENST00000590941.5
ENST00000225441.11
ENST00000426726.8
RUN domain containing 3A
chr16_+_29900345 6.31 ENST00000563177.5
ENST00000483405.5
aspartate beta-hydroxylase domain containing 1
chr3_-_187670385 6.26 ENST00000287641.4
somatostatin
chr19_-_46428869 6.18 ENST00000617053.3
PNMA family member 8C
chr4_+_84583037 6.18 ENST00000295887.6
CDP-diacylglycerol synthase 1
chr10_+_22345445 6.11 ENST00000376603.6
ENST00000456231.6
ENST00000376624.8
ENST00000313311.10
ENST00000435326.5
sperm associated antigen 6
chr8_-_94262308 5.86 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr19_+_55283982 5.83 ENST00000309383.6
BR serine/threonine kinase 1
chr12_+_10212483 5.82 ENST00000545859.5
GABA type A receptor associated protein like 1
chr3_+_159273235 5.80 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr2_-_219543537 5.76 ENST00000373891.2
chondroitin polymerizing factor
chr14_+_103629177 5.72 ENST00000348520.10
ENST00000380038.7
ENST00000389744.8
ENST00000557575.5
ENST00000553286.5
ENST00000347839.10
ENST00000555836.5
ENST00000334553.10
ENST00000246489.11
ENST00000634686.1
ENST00000557450.5
ENST00000452929.6
ENST00000554280.5
ENST00000445352.8
kinesin light chain 1
chr3_+_139935176 5.57 ENST00000458420.7
calsyntenin 2
chr3_+_159852933 5.43 ENST00000482804.1
schwannomin interacting protein 1
chr11_+_109422174 5.40 ENST00000327419.7
chromosome 11 open reading frame 87
chr5_-_138875290 5.38 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chr17_-_58544315 5.33 ENST00000671766.1
ENST00000672673.2
ENST00000321691.3
septin 4
chr2_+_219418369 5.31 ENST00000373960.4
desmin
chr17_-_45132505 5.27 ENST00000619929.5
phospholipase C delta 3
chr16_+_56191476 5.22 ENST00000262493.12
G protein subunit alpha o1
chr8_-_42207557 5.18 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr10_-_96357155 5.11 ENST00000536387.5
oligodendrocytic myelin paranodal and inner loop protein
chr12_+_10212867 5.09 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr4_+_144646145 5.01 ENST00000296575.8
ENST00000434550.2
hedgehog interacting protein
chr9_+_17579059 4.91 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr10_+_62374361 4.91 ENST00000395254.8
zinc finger protein 365
chr1_+_99264275 4.91 ENST00000457765.6
phospholipid phosphatase related 4
chr4_-_155376797 4.91 ENST00000650955.1
ENST00000515654.5
microtubule associated protein 9
chr10_-_89207306 4.87 ENST00000371852.4
cholesterol 25-hydroxylase
chr8_-_42207667 4.76 ENST00000352041.7
ENST00000679151.1
ENST00000679300.1
plasminogen activator, tissue type
chr11_+_117199363 4.72 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr6_-_99349647 4.70 ENST00000389677.6
failed axon connections homolog, metaxin like GST domain containing
chr3_+_99817849 4.68 ENST00000421999.8
cms1 ribosomal small subunit homolog
chr4_+_112818088 4.67 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ankyrin 2
chr6_-_56954747 4.62 ENST00000680361.1
dystonin
chr12_+_10212836 4.57 ENST00000421801.6
ENST00000544284.5
GABA type A receptor associated protein like 1
chr12_+_112418976 4.54 ENST00000635625.1
protein tyrosine phosphatase non-receptor type 11
chr17_+_55264952 4.44 ENST00000226067.10
HLF transcription factor, PAR bZIP family member
chr22_+_38201932 4.42 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAF bZIP transcription factor F
chr1_+_8318088 4.41 ENST00000471889.7
solute carrier family 45 member 1
chr22_+_31122923 4.38 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
inositol polyphosphate-5-phosphatase J
chr6_+_56955353 4.37 ENST00000370745.1
BEN domain containing 6
chr12_+_12785652 4.35 ENST00000356591.5
apolipoprotein L domain containing 1
chr6_+_26204552 4.24 ENST00000615164.2
H4 clustered histone 5
chr17_+_43025203 4.22 ENST00000587250.4
Rho family GTPase 2
chr2_-_219309484 4.21 ENST00000409251.7
ENST00000451506.5
ENST00000446182.5
protein tyrosine phosphatase receptor type N
chr15_+_74995520 4.21 ENST00000562327.5
ENST00000568018.5
ENST00000425597.8
ENST00000562212.5
ENST00000567920.5
ENST00000566872.5
ENST00000361900.10
secretory carrier membrane protein 5
chr11_+_62707668 4.20 ENST00000294117.6
G protein subunit gamma 3
chr15_-_48178144 4.19 ENST00000616409.4
ENST00000324324.12
ENST00000610570.4
myelin expression factor 2
chr7_-_31340678 4.16 ENST00000297142.4
neuronal differentiation 6
chr9_+_135075422 4.12 ENST00000371799.8
ENST00000277415.15
olfactomedin 1
chr6_-_30556477 4.10 ENST00000376621.8
G protein nucleolar 1 (putative)
chr12_+_19236880 4.08 ENST00000536974.5
pleckstrin homology domain containing A5
chr1_+_99264473 4.08 ENST00000370185.9
phospholipid phosphatase related 4
chr10_+_122163672 4.02 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chr12_+_112418889 4.01 ENST00000392597.5
protein tyrosine phosphatase non-receptor type 11
chr16_+_58501468 4.01 ENST00000566656.5
ENST00000566618.5
NDRG family member 4
chr6_-_29628038 3.99 ENST00000355973.7
ENST00000377012.8
gamma-aminobutyric acid type B receptor subunit 1
chr14_+_63204436 3.97 ENST00000316754.8
ras homolog family member J
chr8_+_97775829 3.96 ENST00000517924.5
lysosomal protein transmembrane 4 beta
chr22_+_41560973 3.96 ENST00000306149.12
cold shock domain containing C2
chr2_-_24972032 3.96 ENST00000534855.5
DnaJ heat shock protein family (Hsp40) member C27
chr5_+_72107453 3.96 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr16_+_22814154 3.91 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr8_+_97775775 3.91 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr3_+_8501807 3.87 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr4_-_155376935 3.87 ENST00000311277.9
microtubule associated protein 9
chrX_-_13817027 3.85 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr16_+_1989949 3.82 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr3_-_33718049 3.78 ENST00000468888.6
cytoplasmic linker associated protein 2
chrX_-_13817346 3.73 ENST00000356942.9
glycoprotein M6B
chr2_-_217842154 3.70 ENST00000446688.5
tensin 1
chr4_-_86360039 3.69 ENST00000515650.2
ENST00000641724.1
ENST00000641607.1
ENST00000641324.1
ENST00000641903.1
ENST00000395157.9
ENST00000641823.1
ENST00000641873.1
ENST00000641102.1
ENST00000641462.2
ENST00000641217.1
ENST00000642006.1
ENST00000641020.1
ENST00000641110.1
ENST00000639175.1
ENST00000641485.1
ENST00000641864.1
ENST00000641954.1
ENST00000641647.1
ENST00000641459.1
ENST00000641762.1
ENST00000641777.1
ENST00000641208.1
ENST00000642015.1
ENST00000641493.1
ENST00000642032.1
ENST00000641010.1
ENST00000641287.1
ENST00000641943.1
ENST00000642103.1
ENST00000641047.1
ENST00000641166.1
ENST00000641207.1
mitogen-activated protein kinase 10
chr11_-_119364166 3.68 ENST00000525735.1
ubiquitin specific peptidase 2
chr11_-_123654939 3.68 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr2_+_10911924 3.67 ENST00000295082.3
potassium voltage-gated channel modifier subfamily F member 1
chr20_-_45791865 3.65 ENST00000243938.9
WAP four-disulfide core domain 3
chrX_+_43654888 3.64 ENST00000542639.5
monoamine oxidase A
chr7_-_129952631 3.59 ENST00000473814.6
ENST00000490974.1
ubiquitin conjugating enzyme E2 H
chr15_-_29821473 3.57 ENST00000400011.6
tight junction protein 1
chrX_+_10158448 3.56 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr3_+_158571171 3.54 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr2_+_219544002 3.54 ENST00000421791.1
ENST00000373883.4
ENST00000451952.1
transmembrane protein 198
chrX_+_111096136 3.52 ENST00000372007.10
p21 (RAC1) activated kinase 3
chr18_-_5540515 3.52 ENST00000544123.5
ENST00000585142.5
erythrocyte membrane protein band 4.1 like 3
chr11_-_111911759 3.47 ENST00000650687.2
crystallin alpha B
chr13_+_111320634 3.46 ENST00000283547.2
testis expressed 29
chr2_-_219309350 3.45 ENST00000295718.7
protein tyrosine phosphatase receptor type N
chr3_+_62318983 3.41 ENST00000232519.9
ENST00000462069.6
ENST00000465142.5
chromosome 3 open reading frame 14
chr1_+_92168915 3.38 ENST00000637221.2
BTB domain containing 8
chr20_+_59604527 3.34 ENST00000371015.6
phosphatase and actin regulator 3
chr15_+_68578970 3.31 ENST00000261861.10
coronin 2B
chr10_+_132537778 3.31 ENST00000368594.8
inositol polyphosphate-5-phosphatase A
chr16_-_10580577 3.29 ENST00000359543.8
epithelial membrane protein 2
chr4_+_74445126 3.28 ENST00000395748.8
amphiregulin
chr2_-_182242031 3.28 ENST00000358139.6
phosphodiesterase 1A
chr12_+_112418928 3.27 ENST00000351677.7
ENST00000639857.1
protein tyrosine phosphatase non-receptor type 11
chr10_+_35195124 3.25 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr17_-_7205116 3.25 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr6_+_43243468 3.24 ENST00000259750.9
tau tubulin kinase 1
chr11_-_62689523 3.24 ENST00000317449.5
LRRN4 C-terminal like
chr3_+_99817818 3.21 ENST00000463526.1
cms1 ribosomal small subunit homolog
chr5_-_133612524 3.20 ENST00000265342.12
follistatin like 4
chr10_+_132537814 3.16 ENST00000368593.7
inositol polyphosphate-5-phosphatase A
chr5_+_174724549 3.14 ENST00000239243.7
ENST00000507785.2
msh homeobox 2
chr3_-_100993507 3.13 ENST00000284322.10
ABI family member 3 binding protein
chr19_-_50476725 3.12 ENST00000595790.5
family with sequence similarity 71 member E1
chr5_-_138875362 3.11 ENST00000518785.1
leucine rich repeat transmembrane neuronal 2
chr10_+_122163590 3.08 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr6_+_118548289 3.06 ENST00000357525.6
phospholamban
chr18_+_80109236 3.05 ENST00000262198.9
ENST00000560752.5
ADNP homeobox 2
chr3_-_100993448 3.05 ENST00000495063.6
ENST00000486770.7
ENST00000530539.2
ABI family member 3 binding protein
chr3_-_33718207 3.04 ENST00000359576.9
ENST00000682230.1
ENST00000399362.8
cytoplasmic linker associated protein 2
chr11_-_123654581 3.02 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr9_+_135075520 2.99 ENST00000252854.8
olfactomedin 1
chr1_-_241999091 2.99 ENST00000357246.4
microtubule associated protein 1 light chain 3 gamma
chr3_-_47892743 2.99 ENST00000420772.6
microtubule associated protein 4
chr7_+_5592805 2.97 ENST00000382361.8
fascin actin-bundling protein 1
chr9_+_131289685 2.96 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr19_+_11538767 2.96 ENST00000592923.5
ENST00000535659.6
calponin 1
chr10_+_122163426 2.94 ENST00000360561.7
transforming acidic coiled-coil containing protein 2
chr3_-_100993409 2.92 ENST00000471714.6
ABI family member 3 binding protein
chr3_+_184335906 2.91 ENST00000450976.5
ENST00000418281.5
ENST00000340957.9
ENST00000433578.5
family with sequence similarity 131 member A
chr19_+_12945839 2.90 ENST00000586534.6
ENST00000316856.7
ENST00000592268.5
RAD23 homolog A, nucleotide excision repair protein
chr1_+_109984756 2.88 ENST00000393614.8
ENST00000369799.10
adenosylhomocysteinase like 1
chr12_+_5043873 2.88 ENST00000252321.5
potassium voltage-gated channel subfamily A member 5
chr1_+_66533575 2.86 ENST00000684751.1
ENST00000683291.1
ENST00000682054.1
ENST00000435165.3
ENST00000684539.1
ENST00000681971.1
ENST00000682476.1
ENST00000684168.1
ENST00000371039.5
SH3GL interacting endocytic adaptor 1
chr11_-_31817937 2.85 ENST00000638965.1
ENST00000241001.13
ENST00000638914.3
ENST00000379132.8
ENST00000379129.7
paired box 6
chr16_+_19067989 2.84 ENST00000569127.1
coenzyme Q7, hydroxylase
chr6_-_119078642 2.81 ENST00000621231.4
ENST00000338891.12
family with sequence similarity 184 member A
chr17_-_45133213 2.80 ENST00000538093.1
ENST00000590644.5
phospholipase C delta 3
chr8_-_140764386 2.79 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr1_-_243851066 2.75 ENST00000263826.12
AKT serine/threonine kinase 3
chr6_+_39792298 2.75 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr1_+_156061142 2.74 ENST00000361084.10
RAB25, member RAS oncogene family
chr12_+_56083308 2.74 ENST00000683164.1
ENST00000415288.6
ENST00000683018.1
erb-b2 receptor tyrosine kinase 3
chr19_+_11538844 2.70 ENST00000252456.7
calponin 1
chr14_+_35046334 2.70 ENST00000382406.7
family with sequence similarity 177 member A1
chr2_-_219543793 2.69 ENST00000243776.11
chondroitin polymerizing factor
chr6_+_44247087 2.69 ENST00000353801.7
ENST00000371646.10
heat shock protein 90 alpha family class B member 1
chr2_+_206274643 2.66 ENST00000374423.9
ENST00000649650.1
zinc finger DBF-type containing 2
chr11_-_8810635 2.66 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr5_+_71719267 2.66 ENST00000296777.5
CART prepropeptide
chr6_-_169253835 2.64 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr17_+_7932101 2.63 ENST00000576538.5
ENST00000380262.7
ENST00000563694.6
ENST00000570782.1
centrobin, centriole duplication and spindle assembly protein
chr7_-_37916807 2.62 ENST00000436072.7
secreted frizzled related protein 4
chr8_-_101790934 2.61 ENST00000523645.5
ENST00000520346.1
ENST00000220931.11
ENST00000522448.5
ENST00000522951.5
ENST00000522252.5
ENST00000519098.5
neurocalcin delta
chr4_-_86360071 2.60 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
mitogen-activated protein kinase 10
chr14_+_32329341 2.60 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr1_+_85062304 2.60 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr18_-_34224871 2.58 ENST00000261592.10
nucleolar protein 4
chr11_-_35419542 2.57 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
solute carrier family 1 member 2
chr3_+_62319037 2.56 ENST00000494481.5
chromosome 3 open reading frame 14
chr8_+_26383102 2.56 ENST00000523949.5
BCL2 interacting protein 3 like
chr16_+_19067893 2.54 ENST00000544894.6
ENST00000561858.5
coenzyme Q7, hydroxylase
chr4_+_74445302 2.52 ENST00000502307.1
amphiregulin
chr9_-_127122623 2.51 ENST00000373417.1
ENST00000373425.8
angiopoietin like 2
chr17_-_73311980 2.50 ENST00000439510.2
ENST00000581014.1
ENST00000335793.4
ENST00000579611.1
CDC42 effector protein 4
chr19_+_49119531 2.50 ENST00000334186.9
PTPRF interacting protein alpha 3
chr8_+_40153475 2.50 ENST00000315792.5
transcriptional and immune response regulator
chr4_-_44448796 2.49 ENST00000360029.4
potassium channel tetramerization domain containing 8
chr14_+_35046238 2.49 ENST00000280987.9
family with sequence similarity 177 member A1
chr9_+_34990250 2.49 ENST00000454002.6
ENST00000545841.5
DnaJ heat shock protein family (Hsp40) member B5
chr17_-_80476597 2.48 ENST00000306773.5
neuronal pentraxin 1
chr8_-_140800535 2.47 ENST00000521986.5
ENST00000523539.5
protein tyrosine kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 17.9 GO:1990926 short-term synaptic potentiation(GO:1990926)
4.1 20.4 GO:0010040 response to iron(II) ion(GO:0010040)
3.9 11.8 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
3.2 9.6 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
2.7 8.2 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
2.5 7.6 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
2.5 7.4 GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
2.4 7.3 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
2.2 11.0 GO:0030070 insulin processing(GO:0030070)
2.1 27.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.6 14.5 GO:0055064 chloride ion homeostasis(GO:0055064)
1.5 4.6 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
1.1 4.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.1 7.5 GO:0051012 microtubule sliding(GO:0051012)
1.1 21.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.0 4.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.0 5.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.0 3.0 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.0 3.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
1.0 11.9 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.0 5.7 GO:0035617 stress granule disassembly(GO:0035617)
0.9 3.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.9 2.7 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.9 2.6 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.8 3.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.8 2.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.8 3.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795)
0.8 11.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.7 6.7 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.7 10.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.7 2.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.7 2.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.7 10.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.7 3.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.6 1.9 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.6 27.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.6 4.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.6 6.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.6 0.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.6 2.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.6 1.7 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6 6.8 GO:0003190 atrioventricular valve formation(GO:0003190)
0.6 6.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.5 4.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 7.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 5.8 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.5 2.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.5 2.0 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.5 2.0 GO:2000724 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.5 7.3 GO:0061042 vascular wound healing(GO:0061042)
0.5 2.9 GO:0086018 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018)
0.5 1.4 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.4 1.8 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.4 2.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.4 1.7 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 6.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.4 3.0 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.4 1.7 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 1.7 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.4 4.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.4 4.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4 3.9 GO:0002329 pre-B cell differentiation(GO:0002329)
0.4 6.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.4 1.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.4 3.8 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.4 4.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.4 2.6 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.4 1.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 6.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.4 3.0 GO:0030035 microspike assembly(GO:0030035)
0.4 1.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.4 4.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 2.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 19.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 11.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.4 3.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.4 5.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 4.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 1.7 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.3 6.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.3 4.4 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.3 1.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 18.8 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.3 9.9 GO:0031639 plasminogen activation(GO:0031639)
0.3 0.9 GO:1901491 axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
0.3 4.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.3 5.7 GO:0045475 locomotor rhythm(GO:0045475)
0.3 3.3 GO:0070836 caveola assembly(GO:0070836)
0.3 12.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.3 7.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.3 6.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 2.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 2.6 GO:0010265 SCF complex assembly(GO:0010265)
0.3 1.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.3 2.6 GO:2000322 regulation of glucocorticoid receptor signaling pathway(GO:2000322) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.3 5.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.3 17.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.3 3.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.3 3.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 0.8 GO:1904106 protein localization to microvillus(GO:1904106)
0.3 0.8 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.3 1.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 1.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 1.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 1.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3 8.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 7.9 GO:0045109 intermediate filament organization(GO:0045109)
0.2 5.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.2 2.0 GO:0061709 reticulophagy(GO:0061709)
0.2 1.2 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 2.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2 6.2 GO:0071420 cellular response to histamine(GO:0071420)
0.2 10.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 2.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 6.8 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.3 GO:0051414 response to cortisol(GO:0051414)
0.2 0.7 GO:1903537 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 1.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 10.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 3.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 13.4 GO:0035329 hippo signaling(GO:0035329)
0.2 2.8 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 3.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 0.6 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.4 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.2 1.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.2 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 1.3 GO:0018032 protein amidation(GO:0018032)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.5 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.2 1.8 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 1.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 1.0 GO:0038016 insulin receptor internalization(GO:0038016)
0.2 2.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 3.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.8 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.2 0.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 1.3 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.2 1.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 8.7 GO:0008089 anterograde axonal transport(GO:0008089)
0.2 7.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 1.4 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.2 8.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.8 GO:0060283 growth plate cartilage chondrocyte proliferation(GO:0003419) negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.2 0.9 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.2 2.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 1.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 3.3 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 3.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.9 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 3.9 GO:0060973 cell migration involved in heart development(GO:0060973)
0.1 0.6 GO:0060734 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 4.4 GO:0007567 parturition(GO:0007567)
0.1 2.5 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.1 1.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.5 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 1.0 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.3 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 5.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.9 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 2.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 2.2 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 3.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 2.9 GO:0031268 pseudopodium organization(GO:0031268)
0.1 0.8 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 2.9 GO:0021542 dentate gyrus development(GO:0021542)
0.1 5.0 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1 0.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.5 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 4.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.9 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 4.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.8 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 1.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 2.7 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 3.4 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 2.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.8 GO:0007000 nucleolus organization(GO:0007000)
0.1 6.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.9 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.6 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 1.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 1.8 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.1 0.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.9 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 3.3 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.1 1.4 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.4 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.1 1.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 4.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 5.6 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 3.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 7.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.3 GO:0006828 manganese ion transport(GO:0006828)
0.1 3.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.5 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.1 2.9 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 0.4 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 2.5 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 0.9 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.9 GO:0015820 leucine transport(GO:0015820)
0.1 1.2 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.7 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 1.0 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 1.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.5 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.8 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.8 GO:0006983 ER overload response(GO:0006983)
0.1 0.3 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.3 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.6 GO:0015793 glycerol transport(GO:0015793)
0.1 0.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 9.9 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 3.7 GO:0021762 substantia nigra development(GO:0021762)
0.1 1.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.2 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1 3.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514) spinal cord association neuron differentiation(GO:0021527) regulation of cell fate specification(GO:0042659)
0.0 1.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 4.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 1.5 GO:0061436 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0 0.6 GO:0015871 choline transport(GO:0015871)
0.0 5.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 1.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 7.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.7 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 1.1 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.8 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 3.1 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.9 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 3.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 2.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 1.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.4 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:1902963 modulation of age-related behavioral decline(GO:0090647) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465) smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.5 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 3.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0035058 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 5.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.9 GO:0006379 mRNA cleavage(GO:0006379)
0.0 3.0 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.3 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.8 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.1 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 1.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 2.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.9 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 11.5 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0022028 tangential migration from the subventricular zone to the olfactory bulb(GO:0022028)
0.0 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.2 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 0.2 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.0 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.7 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0000022 mitotic spindle elongation(GO:0000022)
0.0 2.4 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.8 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.8 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 16.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.6 17.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.3 6.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.1 20.2 GO:0044754 autolysosome(GO:0044754)
0.9 2.7 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.8 4.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.8 10.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.6 5.8 GO:0031673 H zone(GO:0031673)
0.6 12.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.6 2.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.6 1.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.6 7.3 GO:0005577 fibrinogen complex(GO:0005577)
0.5 8.8 GO:0097512 cardiac myofibril(GO:0097512)
0.5 2.5 GO:1990742 microvesicle(GO:1990742)
0.5 3.0 GO:0044393 microspike(GO:0044393)
0.5 9.3 GO:0035253 ciliary rootlet(GO:0035253)
0.5 8.2 GO:0042583 chromaffin granule(GO:0042583)
0.5 1.4 GO:0033150 cytoskeletal calyx(GO:0033150)
0.4 11.8 GO:0031045 dense core granule(GO:0031045)
0.4 18.5 GO:0000421 autophagosome membrane(GO:0000421)
0.3 1.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.3 3.3 GO:0000439 core TFIIH complex(GO:0000439)
0.3 10.4 GO:0005614 interstitial matrix(GO:0005614)
0.3 9.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 1.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 22.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 4.9 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3 18.0 GO:0030673 axolemma(GO:0030673)
0.2 6.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 2.7 GO:0031143 pseudopodium(GO:0031143)
0.2 0.4 GO:0043159 acrosomal matrix(GO:0043159)
0.2 9.3 GO:0044295 axonal growth cone(GO:0044295)
0.2 7.9 GO:0030686 90S preribosome(GO:0030686)
0.2 2.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 4.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 3.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 3.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.2 3.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.2 2.8 GO:0016013 syntrophin complex(GO:0016013)
0.2 1.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 2.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 2.4 GO:0034464 BBSome(GO:0034464)
0.2 1.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 5.0 GO:0051233 spindle midzone(GO:0051233)
0.1 2.2 GO:0030478 actin cap(GO:0030478)
0.1 9.6 GO:0043034 costamere(GO:0043034)
0.1 19.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 13.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 12.1 GO:0005871 kinesin complex(GO:0005871)
0.1 6.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 7.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 2.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 9.2 GO:0005776 autophagosome(GO:0005776)
0.1 1.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.7 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 5.1 GO:0005921 gap junction(GO:0005921)
0.1 0.9 GO:0032021 NELF complex(GO:0032021)
0.1 22.4 GO:0043204 perikaryon(GO:0043204)
0.1 5.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 22.9 GO:0030426 growth cone(GO:0030426)
0.1 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 13.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 4.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.5 GO:0071203 WASH complex(GO:0071203)
0.1 9.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 36.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.7 GO:0043194 axon initial segment(GO:0043194)
0.1 6.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 6.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 16.8 GO:0030018 Z disc(GO:0030018)
0.1 7.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.0 GO:0005605 basal lamina(GO:0005605)
0.1 0.9 GO:0070449 elongin complex(GO:0070449)
0.1 4.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 6.4 GO:0042641 actomyosin(GO:0042641)
0.1 2.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.7 GO:0070938 contractile ring(GO:0070938)
0.1 5.9 GO:0005875 microtubule associated complex(GO:0005875)
0.1 4.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 6.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.8 GO:0034709 methylosome(GO:0034709)
0.0 12.1 GO:0043209 myelin sheath(GO:0043209)
0.0 5.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 6.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 7.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 16.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 3.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 5.0 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 2.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 3.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.7 GO:0030017 sarcomere(GO:0030017)
0.0 5.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.8 GO:0034702 ion channel complex(GO:0034702)
0.0 2.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 14.1 GO:0005815 microtubule organizing center(GO:0005815)
0.0 1.6 GO:0015030 Cajal body(GO:0015030)
0.0 6.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.9 GO:0030133 transport vesicle(GO:0030133)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 2.5 GO:0031253 cell projection membrane(GO:0031253)
0.0 10.2 GO:0005768 endosome(GO:0005768)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 5.3 GO:0045177 apical part of cell(GO:0045177)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
2.5 7.4 GO:0036332 VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
1.7 8.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.5 6.2 GO:0004605 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
1.5 12.0 GO:0004111 creatine kinase activity(GO:0004111)
1.3 11.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3 5.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
1.2 21.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.1 27.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.0 3.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
1.0 18.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.9 2.7 GO:0002135 CTP binding(GO:0002135)
0.8 10.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.7 5.0 GO:0097108 hedgehog family protein binding(GO:0097108)
0.7 10.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 6.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.7 4.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.7 2.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.6 9.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.6 3.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.6 6.3 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.6 16.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.6 2.5 GO:0097677 STAT family protein binding(GO:0097677)
0.6 7.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 2.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.6 14.5 GO:0030957 Tat protein binding(GO:0030957)
0.5 3.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 3.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.5 1.5 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.4 1.3 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.4 3.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 2.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 2.9 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.4 2.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 13.6 GO:0002162 dystroglycan binding(GO:0002162)
0.4 15.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.3 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 3.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 10.9 GO:0031489 myosin V binding(GO:0031489)
0.3 0.7 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.3 1.3 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804) L-phenylalanine aminotransferase activity(GO:0070546)
0.3 17.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 4.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 2.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 2.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 3.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 8.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 5.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 4.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 9.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 13.2 GO:0042056 chemoattractant activity(GO:0042056)
0.2 2.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 2.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 3.0 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.9 GO:0010465 neurotrophin receptor activity(GO:0005030) nerve growth factor receptor activity(GO:0010465) neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.2 2.7 GO:0038132 neuregulin binding(GO:0038132)
0.2 4.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 1.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 4.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 4.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 1.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 1.6 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 4.6 GO:0008432 JUN kinase binding(GO:0008432)
0.2 8.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 6.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 10.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 12.8 GO:0030507 spectrin binding(GO:0030507)
0.2 0.8 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 3.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 0.9 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 0.9 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 5.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 7.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.1 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 5.7 GO:0030332 cyclin binding(GO:0030332)
0.1 0.8 GO:0050436 microfibril binding(GO:0050436)
0.1 1.0 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 3.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 7.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 2.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 6.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 12.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 4.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 21.3 GO:0005518 collagen binding(GO:0005518)
0.1 1.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.4 GO:0016015 morphogen activity(GO:0016015)
0.1 0.4 GO:0004040 amidase activity(GO:0004040)
0.1 3.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 4.1 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 16.1 GO:0005179 hormone activity(GO:0005179)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0051373 FATZ binding(GO:0051373)
0.1 4.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 18.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 31.6 GO:0008017 microtubule binding(GO:0008017)
0.1 0.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 1.8 GO:0048156 tau protein binding(GO:0048156)
0.1 2.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.1 5.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 6.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 8.9 GO:0015631 tubulin binding(GO:0015631)
0.1 8.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 13.3 GO:0051213 dioxygenase activity(GO:0051213)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 7.2 GO:0004497 monooxygenase activity(GO:0004497)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.8 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 3.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 2.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 23.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.2 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.1 3.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 4.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348) beta-glucosidase activity(GO:0008422)
0.1 0.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.0 GO:0003796 lysozyme activity(GO:0003796)
0.1 2.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 9.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 1.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 13.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.0 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 3.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 3.6 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 7.7 GO:0051015 actin filament binding(GO:0051015)
0.0 5.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 5.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 2.6 GO:0020037 heme binding(GO:0020037)
0.0 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 3.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.2 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.5 GO:0008137 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 3.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 7.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 4.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0001132 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 17.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.4 7.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 11.8 PID IL5 PATHWAY IL5-mediated signaling events
0.3 4.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 15.7 ST GA12 PATHWAY G alpha 12 Pathway
0.2 2.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 7.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 14.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 15.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 8.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 8.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 5.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 3.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 6.7 PID AURORA B PATHWAY Aurora B signaling
0.1 4.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 4.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 6.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.1 PID AURORA A PATHWAY Aurora A signaling
0.1 4.6 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.1 PID SHP2 PATHWAY SHP2 signaling
0.0 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 11.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 4.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 2.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.1 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.0 27.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.9 31.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 23.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4 4.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 7.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 14.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 7.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.3 8.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 7.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 11.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 8.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 3.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 2.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 5.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 5.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 8.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 6.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 4.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 4.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.1 2.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 6.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 5.9 REACTOME KINESINS Genes involved in Kinesins
0.1 1.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 11.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 6.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 6.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 3.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 3.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 2.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 2.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 4.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 2.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 9.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 3.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 8.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 4.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 14.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 5.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 4.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi