Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for DDIT3

Z-value: 0.85

Motif logo

logo of

Transcription factors associated with DDIT3

Gene Symbol Gene ID Gene Info
DDIT3
ENSG00000175197.13 DNA damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DDIT3hg38_v1_chr12_-_57520480_57520521-0.309.5e-02Click!

Activity profile of DDIT3 motif

Sorted Z-values of DDIT3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_90921079 7.30 ENST00000371697.4
ANKRD1
ankyrin repeat domain 1
chr2_-_178807415 5.04 ENST00000342992.10
ENST00000460472.6
ENST00000589042.5
ENST00000591111.5
ENST00000360870.10
TTN
titin
chr10_-_114685000 2.56 ENST00000369256.6
ABLIM1
actin binding LIM protein 1
chr10_-_114684612 2.41 ENST00000533213.6
ENST00000369252.8
ABLIM1
actin binding LIM protein 1
chr10_-_114684457 2.29 ENST00000392955.7
ABLIM1
actin binding LIM protein 1
chr17_+_4951758 2.10 ENST00000518175.1
ENO3
enolase 3
chr15_+_85380672 1.97 ENST00000361243.6
ENST00000560256.1
AKAP13
A-kinase anchoring protein 13
chr15_+_85380565 1.83 ENST00000559362.5
ENST00000394518.7
AKAP13
A-kinase anchoring protein 13
chr14_+_32329341 1.68 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr5_-_178590367 1.59 ENST00000390654.8
COL23A1
collagen type XXIII alpha 1 chain
chr14_+_32329256 1.56 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chr10_-_17617326 1.56 ENST00000326961.6
ENST00000361271.8
HACD1
3-hydroxyacyl-CoA dehydratase 1
chr10_-_17617235 1.48 ENST00000466335.1
HACD1
3-hydroxyacyl-CoA dehydratase 1
chr2_+_63588992 1.41 ENST00000454035.5
MDH1
malate dehydrogenase 1
chr6_+_144285681 1.23 ENST00000433557.1
UTRN
utrophin
chr22_+_31122923 1.23 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_+_63588953 1.14 ENST00000409908.5
ENST00000442225.5
ENST00000233114.13
ENST00000539945.7
ENST00000409476.5
ENST00000436321.5
MDH1
malate dehydrogenase 1
chr2_+_63589135 1.13 ENST00000432309.6
MDH1
malate dehydrogenase 1
chr7_+_80626148 1.09 ENST00000428497.5
CD36
CD36 molecule
chr15_-_63833911 1.08 ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
ENST00000443617.7
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr6_+_12716760 0.95 ENST00000332995.12
PHACTR1
phosphatase and actin regulator 1
chr15_+_85380625 0.94 ENST00000560302.5
AKAP13
A-kinase anchoring protein 13
chr2_-_40453438 0.93 ENST00000455476.5
SLC8A1
solute carrier family 8 member A1
chr6_+_12716554 0.92 ENST00000676159.1
PHACTR1
phosphatase and actin regulator 1
chr12_+_32485963 0.85 ENST00000531134.7
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_174875505 0.85 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr2_-_63588725 0.64 ENST00000431065.1
WDPCP
WD repeat containing planar cell polarity effector
chr19_+_48755512 0.64 ENST00000593756.6
FGF21
fibroblast growth factor 21
chr14_+_101809795 0.63 ENST00000350249.7
ENST00000557621.5
ENST00000556946.1
PPP2R5C
protein phosphatase 2 regulatory subunit B'gamma
chr13_+_32031706 0.59 ENST00000542859.6
FRY
FRY microtubule binding protein
chr14_+_101809855 0.56 ENST00000557714.1
ENST00000445439.7
ENST00000334743.9
ENST00000557095.5
PPP2R5C
protein phosphatase 2 regulatory subunit B'gamma
chr6_+_12716801 0.56 ENST00000674595.1
PHACTR1
phosphatase and actin regulator 1
chr8_-_18887018 0.55 ENST00000523619.5
PSD3
pleckstrin and Sec7 domain containing 3
chr5_+_112738331 0.53 ENST00000512211.6
APC
APC regulator of WNT signaling pathway
chr1_+_89843421 0.53 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 VRAC subunit D
chr11_+_18602969 0.53 ENST00000636011.1
ENST00000542172.1
SPTY2D1OS
SPTY2D1 opposite strand
chr18_-_57621741 0.50 ENST00000587194.1
ENST00000591599.5
ENST00000588661.5
ENST00000256854.10
NARS1
asparaginyl-tRNA synthetase 1
chr1_+_61203496 0.48 ENST00000663597.1
NFIA
nuclear factor I A
chr17_+_58238694 0.47 ENST00000581008.1
LPO
lactoperoxidase
chr20_+_56412112 0.46 ENST00000360314.7
CASS4
Cas scaffold protein family member 4
chr14_+_21797272 0.44 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr5_+_146203544 0.42 ENST00000506502.2
ENSG00000275740.1
novel readthrough transcript
chr1_-_149861210 0.42 ENST00000579512.2
H4C15
H4 clustered histone 15
chr21_-_30492008 0.41 ENST00000334063.6
KRTAP19-3
keratin associated protein 19-3
chr20_+_56412393 0.40 ENST00000679529.1
CASS4
Cas scaffold protein family member 4
chr3_-_122993232 0.40 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
SEMA5B
semaphorin 5B
chr9_-_92293674 0.40 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
IARS1
isoleucyl-tRNA synthetase 1
chr12_-_7747339 0.38 ENST00000543765.1
ENST00000360345.8
ENST00000540085.5
CLEC4C
C-type lectin domain family 4 member C
chr7_-_44490609 0.38 ENST00000355451.8
NUDCD3
NudC domain containing 3
chr8_-_21812320 0.37 ENST00000517328.5
GFRA2
GDNF family receptor alpha 2
chr5_+_72848161 0.37 ENST00000506351.6
TNPO1
transportin 1
chr3_+_1093002 0.37 ENST00000446702.7
CNTN6
contactin 6
chr12_-_52680398 0.35 ENST00000252244.3
KRT1
keratin 1
chr3_-_56468346 0.35 ENST00000288221.11
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr19_-_6459735 0.35 ENST00000334510.9
ENST00000301454.9
SLC25A23
solute carrier family 25 member 23
chr14_-_22976812 0.32 ENST00000553592.5
AJUBA
ajuba LIM protein
chr1_+_113905156 0.31 ENST00000650596.1
DCLRE1B
DNA cross-link repair 1B
chr9_+_109780312 0.31 ENST00000483909.5
ENST00000413420.5
ENST00000302798.7
PALM2AKAP2
PALM2 and AKAP2 fusion
chr17_-_49848017 0.29 ENST00000326219.5
ENST00000334568.8
ENST00000352793.6
ENST00000398154.5
ENST00000436235.5
TAC4
tachykinin precursor 4
chr1_-_152224193 0.29 ENST00000368801.4
HRNR
hornerin
chr1_+_111227672 0.29 ENST00000474304.6
CHI3L2
chitinase 3 like 2
chr2_-_63588390 0.28 ENST00000272321.12
ENST00000409562.7
WDPCP
WD repeat containing planar cell polarity effector
chr1_+_149832647 0.27 ENST00000578186.2
H4C14
H4 clustered histone 14
chr4_+_183659267 0.27 ENST00000357207.8
ENST00000334690.11
TRAPPC11
trafficking protein particle complex 11
chr14_-_22976793 0.27 ENST00000553911.1
AJUBA
ajuba LIM protein
chr18_-_63158208 0.26 ENST00000678301.1
BCL2
BCL2 apoptosis regulator
chr21_-_44914271 0.26 ENST00000522931.5
ITGB2
integrin subunit beta 2
chr10_-_102114935 0.24 ENST00000361198.9
LDB1
LIM domain binding 1
chr10_-_24706622 0.22 ENST00000680286.1
ARHGAP21
Rho GTPase activating protein 21
chr5_+_119476530 0.22 ENST00000645099.1
ENST00000513628.5
HSD17B4
hydroxysteroid 17-beta dehydrogenase 4
chr11_-_10294194 0.22 ENST00000676387.1
ENST00000256190.13
ENST00000675281.1
SBF2
SET binding factor 2
chr1_-_19923617 0.22 ENST00000375116.3
PLA2G2E
phospholipase A2 group IIE
chr4_-_98657635 0.21 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
TSPAN5
tetraspanin 5
chrX_-_52517213 0.21 ENST00000375616.5
XAGE1B
X antigen family member 1B
chrX_+_52495791 0.21 ENST00000375602.2
ENST00000375600.5
XAGE1A
X antigen family member 1A
chr15_+_40952962 0.20 ENST00000444189.7
CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr2_+_226835936 0.19 ENST00000341329.7
ENST00000437454.5
ENST00000443477.5
ENST00000423616.1
ENST00000392062.7
ENST00000448992.5
RHBDD1
rhomboid domain containing 1
chr7_+_44000889 0.18 ENST00000258704.3
SPDYE1
speedy/RINGO cell cycle regulator family member E1
chr5_-_132295236 0.18 ENST00000431054.5
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr6_-_157323498 0.18 ENST00000400788.9
ENST00000367144.4
TMEM242
transmembrane protein 242
chr19_+_1450113 0.18 ENST00000590469.6
ENST00000590877.5
ENST00000233607.6
APC2
APC regulator of WNT signaling pathway 2
chr7_-_99408548 0.17 ENST00000626285.1
ENST00000350498.8
PDAP1
PDGFA associated protein 1
chr3_-_9553796 0.15 ENST00000287585.8
LHFPL4
LHFPL tetraspan subfamily member 4
chr9_+_122723990 0.15 ENST00000259466.1
OR1L4
olfactory receptor family 1 subfamily L member 4
chr19_-_35501878 0.15 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
DMKN
dermokine
chr2_+_6978624 0.15 ENST00000433456.1
RNF144A
ring finger protein 144A
chr3_+_37975773 0.15 ENST00000436654.1
CTDSPL
CTD small phosphatase like
chr12_+_64405046 0.15 ENST00000540203.5
XPOT
exportin for tRNA
chr20_+_56412249 0.15 ENST00000679887.1
ENST00000434344.2
CASS4
Cas scaffold protein family member 4
chr13_+_24270841 0.14 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr9_+_107283137 0.14 ENST00000419616.5
RAD23B
RAD23 homolog B, nucleotide excision repair protein
chr4_+_140257286 0.14 ENST00000394205.7
SCOC
short coiled-coil protein
chr8_-_92017292 0.13 ENST00000521553.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr9_+_109780292 0.12 ENST00000374530.7
PALM2AKAP2
PALM2 and AKAP2 fusion
chr3_+_44799187 0.12 ENST00000425755.5
KIF15
kinesin family member 15
chr3_+_9423108 0.12 ENST00000468208.2
SETD5
SET domain containing 5
chr12_+_106601137 0.11 ENST00000357881.8
RFX4
regulatory factor X4
chr5_+_146203593 0.11 ENST00000265271.7
RBM27
RNA binding motif protein 27
chr14_+_21894433 0.11 ENST00000390438.2
TRAV8-4
T cell receptor alpha variable 8-4
chr15_-_63833875 0.11 ENST00000560316.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr7_-_56034133 0.10 ENST00000421626.5
PSPH
phosphoserine phosphatase
chr17_+_58238426 0.10 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
LPO
lactoperoxidase
chr9_+_109780179 0.10 ENST00000314527.9
PALM2AKAP2
PALM2 and AKAP2 fusion
chr1_-_113905020 0.10 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
AP4B1
adaptor related protein complex 4 subunit beta 1
chr12_-_109309218 0.10 ENST00000355216.5
FOXN4
forkhead box N4
chr10_+_100997040 0.10 ENST00000370223.7
LZTS2
leucine zipper tumor suppressor 2
chr1_+_111227610 0.10 ENST00000369744.6
CHI3L2
chitinase 3 like 2
chr19_+_10625507 0.09 ENST00000590857.5
ENST00000588688.5
ENST00000586078.5
ENST00000335757.10
SLC44A2
solute carrier family 44 member 2
chr11_-_69704013 0.09 ENST00000294312.4
FGF19
fibroblast growth factor 19
chr1_+_111227699 0.09 ENST00000369748.9
CHI3L2
chitinase 3 like 2
chr20_+_6007245 0.08 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr17_+_4433904 0.08 ENST00000355530.7
SPNS3
sphingolipid transporter 3 (putative)
chr11_+_4586791 0.08 ENST00000641486.1
OR52I2
olfactory receptor family 52 subfamily I member 2
chr11_+_20022550 0.08 ENST00000533917.5
NAV2
neuron navigator 2
chr5_+_154755272 0.08 ENST00000518297.6
LARP1
La ribonucleoprotein 1, translational regulator
chr7_+_18290089 0.08 ENST00000433709.6
HDAC9
histone deacetylase 9
chr2_-_182242031 0.07 ENST00000358139.6
PDE1A
phosphodiesterase 1A
chr1_+_222737283 0.07 ENST00000360827.6
FAM177B
family with sequence similarity 177 member B
chrX_+_30235894 0.07 ENST00000620842.1
MAGEB3
MAGE family member B3
chr8_+_27771942 0.07 ENST00000523566.5
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_-_121579638 0.06 ENST00000446152.6
KDM2B
lysine demethylase 2B
chr4_+_157076119 0.05 ENST00000541722.5
ENST00000264428.9
ENST00000512619.5
GLRB
glycine receptor beta
chr3_+_136957948 0.05 ENST00000329582.9
IL20RB
interleukin 20 receptor subunit beta
chr1_+_152842851 0.05 ENST00000431011.3
LCE6A
late cornified envelope 6A
chrX_-_134658450 0.04 ENST00000359237.9
PLAC1
placenta enriched 1
chr2_-_227724757 0.04 ENST00000641918.1
SCYGR6
small cysteine and glycine repeat containing 6
chr9_-_74887720 0.04 ENST00000449912.6
TRPM6
transient receptor potential cation channel subfamily M member 6
chr14_-_55191534 0.03 ENST00000395425.6
ENST00000247191.7
DLGAP5
DLG associated protein 5
chr5_+_141364231 0.03 ENST00000611914.1
PCDHGA5
protocadherin gamma subfamily A, 5
chrX_-_139642835 0.03 ENST00000536274.5
MCF2
MCF.2 cell line derived transforming sequence
chr1_+_33081145 0.03 ENST00000294517.11
ENST00000373443.7
AZIN2
antizyme inhibitor 2
chr15_+_40953463 0.03 ENST00000617768.5
CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chrX_-_139642518 0.02 ENST00000370573.8
ENST00000338585.6
MCF2
MCF.2 cell line derived transforming sequence
chr1_-_113904789 0.02 ENST00000369569.6
ENST00000369567.5
AP4B1
adaptor related protein complex 4 subunit beta 1
chr17_-_79993634 0.02 ENST00000571872.1
TBC1D16
TBC1 domain family member 16
chr2_-_158456702 0.02 ENST00000409889.1
ENST00000283233.10
CCDC148
coiled-coil domain containing 148
chrX_-_139642889 0.01 ENST00000370576.9
MCF2
MCF.2 cell line derived transforming sequence
chr8_+_26577843 0.01 ENST00000311151.9
DPYSL2
dihydropyrimidinase like 2
chr7_-_138679045 0.01 ENST00000419765.4
SVOPL
SVOP like
chrX_-_100874209 0.00 ENST00000372964.5
ENST00000217885.5
NOX1
NADPH oxidase 1
chr12_-_109309278 0.00 ENST00000299162.10
FOXN4
forkhead box N4

Network of associatons between targets according to the STRING database.

First level regulatory network of DDIT3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.5 4.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.4 3.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 7.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2 3.7 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.9 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 2.9 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.6 GO:1904640 response to methionine(GO:1904640)
0.1 1.1 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 1.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.5 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.3 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 8.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0031627 telomeric loop formation(GO:0031627)
0.0 1.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 2.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.0 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 2.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.0 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 3.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 5.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.3 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.2 GO:0070938 contractile ring(GO:0070938)
0.1 7.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 4.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 7.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0044447 axoneme part(GO:0044447)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.8 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.2 3.7 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
1.0 3.0 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.3 5.0 GO:0031433 telethonin binding(GO:0031433)
0.3 4.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 3.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.9 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.2 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 2.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 5.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 5.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 7.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins