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Illumina Body Map 2 (GSE30611)

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Results for DMBX1

Z-value: 0.59

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Transcription factors associated with DMBX1

Gene Symbol Gene ID Gene Info
ENSG00000197587.11 diencephalon/mesencephalon homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DMBX1hg38_v1_chr1_+_46489800_464898420.531.8e-03Click!

Activity profile of DMBX1 motif

Sorted Z-values of DMBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_3372666 2.25 ENST00000399974.5
MT-RNR2 like 4
chr2_-_174846405 2.00 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr5_+_170232912 1.25 ENST00000524171.5
ENST00000517575.4
ENST00000518395.2
ENST00000593851.5
chromosome 5 open reading frame 58
chr12_-_21334858 1.19 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
solute carrier organic anion transporter family member 1A2
chr14_-_106511856 1.11 ENST00000390622.2
immunoglobulin heavy variable 1-46
chr12_-_54981838 1.06 ENST00000316577.12
thymocyte expressed, positive selection associated 1
chr7_+_148339452 0.98 ENST00000463592.3
contactin associated protein 2
chr20_-_45101112 0.86 ENST00000306117.5
ENST00000537075.3
potassium voltage-gated channel modifier subfamily S member 1
chr12_-_62192762 0.85 ENST00000416284.8
TAFA chemokine like family member 2
chr5_-_55692731 0.79 ENST00000502247.1
solute carrier family 38 member 9
chr7_-_135728177 0.77 ENST00000682651.1
ENST00000354042.8
solute carrier family 13 member 4
chr18_-_37565765 0.77 ENST00000361795.9
ENST00000420428.7
CUGBP Elav-like family member 4
chr11_+_61481110 0.76 ENST00000338608.7
ENST00000432063.6
protein phosphatase 1 regulatory subunit 32
chr12_-_49187369 0.74 ENST00000547939.6
tubulin alpha 1a
chr14_+_21736136 0.71 ENST00000390426.2
T cell receptor alpha variable 4
chr20_+_33217325 0.69 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chrX_-_103311004 0.68 ENST00000372674.5
brain expressed X-linked 2
chr18_+_54591159 0.67 ENST00000321600.1
ENST00000648945.2
dynactin associated protein
chr14_+_21797272 0.66 ENST00000390430.2
T cell receptor alpha variable 8-1
chr5_-_55692620 0.63 ENST00000503817.5
ENST00000512595.5
solute carrier family 38 member 9
chr12_+_57578238 0.62 ENST00000675907.1
kinesin family member 5A
chr14_+_96797304 0.61 ENST00000553683.2
ENST00000680538.1
ENST00000681195.1
ENST00000679727.1
ENST00000680509.1
ENST00000557222.6
ENST00000680683.1
ENST00000680335.1
ENST00000216639.8
ENST00000679736.1
ENST00000681176.1
ENST00000557352.2
ENST00000679903.1
ENST00000681419.1
ENST00000680849.1
ENST00000681493.1
ENST00000679770.1
ENST00000681355.1
ENST00000681344.1
VRK serine/threonine kinase 1
chr18_-_37565628 0.60 ENST00000334919.9
ENST00000591282.5
ENST00000588597.5
CUGBP Elav-like family member 4
chr7_+_142450941 0.57 ENST00000390368.2
T cell receptor beta variable 6-5
chr18_-_37565714 0.57 ENST00000591287.5
ENST00000601019.5
ENST00000601392.5
CUGBP Elav-like family member 4
chr16_-_31065011 0.56 ENST00000539836.3
ENST00000535577.5
ENST00000442862.2
zinc finger protein 668
chr1_+_19882374 0.52 ENST00000375120.4
OTU deubiquitinase 3
chr10_-_97270638 0.51 ENST00000371027.5
Rho GTPase activating protein 19
chr17_+_50834581 0.50 ENST00000426127.1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr2_+_130755531 0.49 ENST00000321420.5
APC membrane recruitment protein 3
chr19_+_40778216 0.48 ENST00000594800.5
ENST00000357052.8
ENST00000602173.5
RAB4B, member RAS oncogene family
chr2_-_27264083 0.48 ENST00000432351.5
solute carrier family 30 member 3
chr7_-_100177336 0.48 ENST00000292377.4
glypican 2
chr4_+_625555 0.48 ENST00000496514.6
ENST00000255622.10
phosphodiesterase 6B
chr19_-_42412347 0.47 ENST00000601189.1
ENST00000599211.1
lipase E, hormone sensitive type
chr17_-_50129792 0.47 ENST00000503131.1
sterile alpha motif domain containing 14
chr1_+_206214723 0.47 ENST00000572793.2
SLIT-ROBO Rho GTPase activating protein 2
chr3_+_188947199 0.46 ENST00000433971.5
tumor protein p63 regulated 1
chr11_+_121576760 0.46 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr18_-_37565825 0.44 ENST00000603232.6
CUGBP Elav-like family member 4
chr11_+_44565627 0.44 ENST00000532544.5
ENST00000525210.5
ENST00000227155.9
ENST00000527737.5
ENST00000524704.5
CD82 molecule
chr3_-_19934189 0.43 ENST00000295824.14
EF-hand domain family member B
chr12_-_118190510 0.42 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr6_+_130018565 0.41 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr5_+_176313080 0.39 ENST00000332772.4
SUMO interacting motifs containing 1
chrX_-_15854743 0.39 ENST00000450644.2
adaptor related protein complex 1 subunit sigma 2
chr3_-_49021045 0.37 ENST00000440857.5
DALR anticodon binding domain containing 3
chr8_-_124565699 0.36 ENST00000519168.5
MTSS I-BAR domain containing 1
chr7_+_142469521 0.34 ENST00000390371.3
T cell receptor beta variable 6-6
chr17_-_4739866 0.34 ENST00000574412.6
ENST00000293778.12
C-X-C motif chemokine ligand 16
chr16_-_31064952 0.34 ENST00000426488.6
zinc finger protein 668
chr12_-_76067469 0.33 ENST00000551524.5
nucleosome assembly protein 1 like 1
chr14_-_106875069 0.33 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr19_+_45498439 0.33 ENST00000451287.7
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr15_+_81182579 0.32 ENST00000302987.9
interleukin 16
chr3_-_56977354 0.32 ENST00000473779.5
Rho guanine nucleotide exchange factor 3
chr11_+_44565591 0.32 ENST00000342935.7
CD82 molecule
chr3_+_49020443 0.31 ENST00000326912.8
NADH:ubiquinone oxidoreductase complex assembly factor 3
chrX_-_15854791 0.31 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
adaptor related protein complex 1 subunit sigma 2
chr12_+_53300027 0.31 ENST00000549488.5
MYG1 exonuclease
chr6_+_42746958 0.31 ENST00000614467.4
BRD4 interacting chromatin remodeling complex associated protein like
chr3_-_151203201 0.30 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr15_+_73873604 0.26 ENST00000535547.6
ENST00000562056.1
TBC1 domain family member 21
chr17_+_4740005 0.26 ENST00000269289.10
zinc finger MYND-type containing 15
chr20_+_35968566 0.26 ENST00000373973.7
ENST00000349339.5
ENST00000489667.1
ENST00000538900.1
cyclic nucleotide binding domain containing 2
chr17_+_4740042 0.26 ENST00000592813.5
zinc finger MYND-type containing 15
chr18_-_72865680 0.26 ENST00000397929.5
neuropilin and tolloid like 1
chr15_+_73873557 0.25 ENST00000300504.7
TBC1 domain family member 21
chr10_+_84245038 0.25 ENST00000650682.1
ENST00000358110.7
ENST00000651237.1
ENST00000652122.1
ENST00000652092.2
ENST00000359452.9
ENST00000483744.6
retinal G protein coupled receptor
chr1_-_47314089 0.25 ENST00000360380.7
ENST00000371877.8
ENST00000447475.7
STIL centriolar assembly protein
chr1_-_28058087 0.25 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr19_-_17075038 0.24 ENST00000593360.1
HAUS augmin like complex subunit 8
chr5_+_72107453 0.22 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr19_-_17075418 0.20 ENST00000253669.10
HAUS augmin like complex subunit 8
chr12_+_7789393 0.20 ENST00000229307.9
Nanog homeobox
chr1_-_121184292 0.19 ENST00000452190.2
ENST00000619376.4
ENST00000369390.7
family with sequence similarity 72 member B
chr1_+_206203541 0.18 ENST00000573034.8
SLIT-ROBO Rho GTPase activating protein 2
chr17_-_40703744 0.18 ENST00000264651.3
keratin 24
chrX_-_65534721 0.18 ENST00000677969.1
ENST00000374807.9
ENST00000374804.9
ENST00000677087.1
ENST00000374811.8
ENST00000676986.1
ENST00000678823.1
ENST00000678570.1
LAS1 like ribosome biogenesis factor
chr11_-_45918789 0.17 ENST00000532681.5
peroxisomal biogenesis factor 16
chr4_-_75990919 0.17 ENST00000395711.8
ENST00000356260.10
SDA1 domain containing 1
chr1_-_143971965 0.17 ENST00000369175.4
ENST00000584486.6
family with sequence similarity 72 member C
chr8_+_85987287 0.17 ENST00000521564.1
ATPase H+ transporting V0 subunit d2
chr19_-_50637939 0.17 ENST00000338916.8
synaptotagmin 3
chr8_-_100145802 0.17 ENST00000428847.3
F-box protein 43
chr15_-_48810583 0.17 ENST00000558591.1
centrosomal protein 152
chr21_-_33643926 0.16 ENST00000438788.1
crystallin zeta like 1
chr1_+_121184964 0.16 ENST00000367123.8
SLIT-ROBO Rho GTPase activating protein 2C
chr15_+_92900189 0.15 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr3_-_149752443 0.14 ENST00000473414.6
COMM domain containing 2
chr3_+_136930469 0.14 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr1_-_206202827 0.13 ENST00000431655.2
ENST00000367128.8
family with sequence similarity 72 member A
chr2_-_70553638 0.12 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr19_+_17337539 0.10 ENST00000324894.13
ENST00000358792.11
ENST00000600625.5
GTP binding protein 3, mitochondrial
chr4_-_53365976 0.10 ENST00000401642.8
ENST00000388940.8
ENST00000503450.1
sec1 family domain containing 2
chr2_-_207624983 0.08 ENST00000448007.6
ENST00000432416.5
ENST00000411432.5
ENST00000458426.5
ENST00000406927.6
ENST00000425132.5
methyltransferase like 21A
chr15_-_60391127 0.07 ENST00000559350.5
ENST00000558986.5
ENST00000560389.5
annexin A2
chr18_+_31447732 0.06 ENST00000257189.5
desmoglein 3
chr10_+_102226293 0.06 ENST00000370005.4
ELOVL fatty acid elongase 3
chr5_-_140564245 0.06 ENST00000412920.7
ENST00000511201.2
ENST00000354402.9
ENST00000356738.6
amyloid beta precursor protein binding family B member 3
chr2_-_70553440 0.05 ENST00000450929.5
transforming growth factor alpha
chr18_-_55587335 0.05 ENST00000638154.3
transcription factor 4
chr10_+_102132994 0.05 ENST00000413464.6
ENST00000278070.7
PPARG related coactivator 1
chr17_-_7239279 0.05 ENST00000613632.4
ENST00000571362.5
ENST00000576955.5
ENST00000320316.8
PHD finger protein 23
chr1_-_145095528 0.04 ENST00000612199.4
ENST00000641863.1
SLIT-ROBO Rho GTPase activating protein 2B
chr1_+_145095967 0.04 ENST00000400889.3
family with sequence similarity 72 member D
chr17_-_41309253 0.04 ENST00000391352.1
keratin associated protein 16-1
chr9_-_21994345 0.04 ENST00000579755.2
ENST00000530628.2
cyclin dependent kinase inhibitor 2A
chr4_-_169757873 0.02 ENST00000393381.3
histone PARylation factor 1
chr1_-_45499931 0.02 ENST00000626657.2
coiled-coil domain containing 163
chr11_-_101907934 0.01 ENST00000534527.1
angiopoietin like 5
chr19_-_5286163 0.01 ENST00000592099.5
ENST00000588012.5
ENST00000262963.10
ENST00000587303.5
ENST00000590509.5
protein tyrosine phosphatase receptor type S

Network of associatons between targets according to the STRING database.

First level regulatory network of DMBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 2.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.2 0.6 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 0.5 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.5 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.1 1.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.8 GO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.6 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 0.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.8 GO:0008272 sulfate transport(GO:0008272)
0.0 2.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.9 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 1.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.0 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0042835 BRE binding(GO:0042835)
0.2 0.5 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.2 0.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.6 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 2.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels