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Illumina Body Map 2 (GSE30611)
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Results for DUXA
Z-value: 1.26
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Transcription factors associated with DUXA
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| DUXA | hg38_v1_chr19_-_57167485_57167485 | -0.38 | 3.1e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of DUXA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.9 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 6.6 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.5 | 4.9 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.1 | 4.9 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.2 | 3.8 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 2.9 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
| 0.1 | 2.3 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.3 | 2.2 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 0.2 | 2.0 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.1 | 2.0 | GO:0016540 | protein autoprocessing(GO:0016540) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 7.2 | GO:0030018 | Z disc(GO:0030018) |
| 0.2 | 4.9 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.2 | 3.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 2.9 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 2.4 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 2.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 2.2 | GO:0043034 | costamere(GO:0043034) |
| 0.5 | 1.9 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.1 | 1.7 | GO:0060077 | inhibitory synapse(GO:0060077) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.8 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 5.7 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 5.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 4.9 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 4.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 2.8 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 2.5 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 2.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 2.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 2.0 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.9 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 3.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 2.3 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 2.0 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.0 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.0 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.7 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.9 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 4.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 2.2 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 2.0 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.5 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 1.4 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 1.3 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.2 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.1 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |