Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for DUXA

Z-value: 1.26

Motif logo

logo of

Transcription factors associated with DUXA

Gene Symbol Gene ID Gene Info
DUXA
ENSG00000258873.3 double homeobox A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DUXAhg38_v1_chr19_-_57167485_57167485-0.383.1e-02Click!

Activity profile of DUXA motif

Sorted Z-values of DUXA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_6483728 3.52 ENST00000675459.1
ENST00000551752.5
RBFOX1
RNA binding fox-1 homolog 1
chr2_-_174764436 3.33 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
chr16_+_6483813 2.30 ENST00000675653.1
RBFOX1
RNA binding fox-1 homolog 1
chr10_+_68106109 2.28 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr6_+_54018910 2.12 ENST00000514921.5
ENST00000274897.9
ENST00000370877.6
MLIP
muscular LMNA interacting protein
chr3_-_196515315 2.07 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr10_-_67665642 1.99 ENST00000682945.1
ENST00000330298.6
ENST00000682758.1
CTNNA3
catenin alpha 3
chr10_-_29522527 1.99 ENST00000632315.1
SVIL
supervillin
chr15_-_42457556 1.88 ENST00000565948.1
ZNF106
zinc finger protein 106
chr5_+_142770367 1.84 ENST00000645722.2
ENST00000274498.9
ARHGAP26
Rho GTPase activating protein 26
chr3_+_160225409 1.73 ENST00000326474.5
C3orf80
chromosome 3 open reading frame 80
chr8_-_106770235 1.69 ENST00000311955.4
ABRA
actin binding Rho activating protein
chr2_-_174764407 1.55 ENST00000409219.5
ENST00000409542.5
CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
chr1_+_77918128 1.51 ENST00000342754.5
NEXN
nexilin F-actin binding protein
chr5_+_68239815 1.48 ENST00000520675.1
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr4_-_46124046 1.42 ENST00000295452.5
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
chr2_-_223602284 1.42 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
SCG2
secretogranin II
chr6_+_54018992 1.41 ENST00000509997.5
MLIP
muscular LMNA interacting protein
chr5_+_174045673 1.41 ENST00000303177.8
ENST00000519867.5
NSG2
neuronal vesicle trafficking associated 2
chr10_-_29634964 1.38 ENST00000375398.6
ENST00000355867.8
SVIL
supervillin
chr8_-_7056729 1.36 ENST00000330590.4
DEFA5
defensin alpha 5
chr5_+_98773651 1.36 ENST00000513185.3
RGMB
repulsive guidance molecule BMP co-receptor b
chr5_-_79514127 1.32 ENST00000334082.11
HOMER1
homer scaffold protein 1
chr18_-_77127935 1.29 ENST00000581878.5
MBP
myelin basic protein
chr3_-_39280021 1.29 ENST00000399220.3
CX3CR1
C-X3-C motif chemokine receptor 1
chr16_+_6483379 1.24 ENST00000552089.5
RBFOX1
RNA binding fox-1 homolog 1
chr7_+_80646436 1.24 ENST00000419819.2
CD36
CD36 molecule
chr1_-_13285154 1.22 ENST00000357367.6
ENST00000614831.1
PRAMEF8
PRAME family member 8
chrX_+_155216452 1.14 ENST00000286428.7
VBP1
VHL binding protein 1
chr10_-_60141004 1.12 ENST00000355288.6
ANK3
ankyrin 3
chr19_-_50968125 1.10 ENST00000594641.1
KLK6
kallikrein related peptidase 6
chr6_+_12717660 1.09 ENST00000674637.1
PHACTR1
phosphatase and actin regulator 1
chr11_+_49028823 1.08 ENST00000332682.9
TRIM49B
tripartite motif containing 49B
chr11_-_133956957 1.07 ENST00000533871.8
IGSF9B
immunoglobulin superfamily member 9B
chr11_-_89807220 1.07 ENST00000532501.2
TRIM49
tripartite motif containing 49
chr22_+_31122923 1.02 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_-_40453438 1.02 ENST00000455476.5
SLC8A1
solute carrier family 8 member A1
chr19_-_3061403 1.01 ENST00000586839.1
TLE5
TLE family member 5, transcriptional modulator
chr17_-_59081162 1.01 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr2_+_54115437 1.00 ENST00000303536.8
ENST00000394666.7
ACYP2
acylphosphatase 2
chr1_+_12857086 0.99 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr1_-_42335869 0.98 ENST00000372573.5
FOXJ3
forkhead box J3
chr2_+_148875214 0.97 ENST00000435030.6
ENST00000677891.1
ENST00000677843.1
ENST00000678056.1
ENST00000677280.1
KIF5C
kinesin family member 5C
chr18_-_3219849 0.95 ENST00000261606.11
MYOM1
myomesin 1
chr4_-_175907143 0.93 ENST00000513365.1
ENST00000513667.5
ENST00000503563.1
GPM6A
glycoprotein M6A
chr1_+_12916610 0.93 ENST00000616979.4
PRAMEF7
PRAME family member 7
chr18_-_3219961 0.92 ENST00000356443.9
MYOM1
myomesin 1
chr5_+_36606355 0.92 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
SLC1A3
solute carrier family 1 member 3
chr19_-_50968775 0.91 ENST00000391808.5
KLK6
kallikrein related peptidase 6
chr12_-_44921842 0.91 ENST00000552993.5
NELL2
neural EGFL like 2
chr21_+_33025927 0.88 ENST00000430860.1
ENST00000382357.4
ENST00000333337.3
OLIG2
oligodendrocyte transcription factor 2
chr16_-_21303036 0.87 ENST00000219599.8
ENST00000576703.5
CRYM
crystallin mu
chr4_+_48483324 0.87 ENST00000273861.5
SLC10A4
solute carrier family 10 member 4
chr20_-_10420737 0.87 ENST00000649912.1
ENSG00000285723.1
novel protein
chr4_-_6555609 0.85 ENST00000507294.1
PPP2R2C
protein phosphatase 2 regulatory subunit Bgamma
chr12_-_10909562 0.82 ENST00000390677.2
TAS2R13
taste 2 receptor member 13
chr1_+_13070853 0.81 ENST00000619661.2
PRAMEF25
PRAME family member 25
chr1_+_12773738 0.80 ENST00000357726.5
PRAMEF12
PRAME family member 12
chr5_-_17655843 0.80 ENST00000598383.3
H3Y1
H3.Y histone 1
chr11_-_89920428 0.80 ENST00000605881.5
TRIM49D1
tripartite motif containing 49D1
chr4_+_75724569 0.80 ENST00000514213.7
ENST00000264904.8
USO1
USO1 vesicle transport factor
chr5_+_17604177 0.79 ENST00000510838.2
TAF11L11
TATA-box binding protein associated factor 11 like 11
chr14_-_80231052 0.79 ENST00000557010.5
DIO2
iodothyronine deiodinase 2
chr1_+_13068677 0.78 ENST00000614839.4
PRAMEF25
PRAME family member 25
chr16_-_57186014 0.78 ENST00000566584.5
ENST00000566481.5
ENST00000566077.5
ENST00000564108.5
ENST00000309137.13
ENST00000565458.5
ENST00000566681.1
ENST00000567439.5
PSME3IP1
proteasome activator subunit 3 interacting protein 1
chrX_+_86714623 0.76 ENST00000484479.1
DACH2
dachshund family transcription factor 2
chr7_-_14902743 0.76 ENST00000402815.6
DGKB
diacylglycerol kinase beta
chr4_-_141212877 0.75 ENST00000420921.6
RNF150
ring finger protein 150
chr7_-_14902842 0.74 ENST00000407950.5
DGKB
diacylglycerol kinase beta
chr16_-_57185808 0.73 ENST00000562406.5
ENST00000568671.5
ENST00000567044.5
PSME3IP1
proteasome activator subunit 3 interacting protein 1
chr6_-_70957029 0.71 ENST00000230053.11
B3GAT2
beta-1,3-glucuronyltransferase 2
chr3_+_108602776 0.71 ENST00000497905.5
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr11_+_28108248 0.69 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
METTL15
methyltransferase like 15
chr19_+_52429181 0.69 ENST00000301085.8
ZNF534
zinc finger protein 534
chr17_+_68515399 0.69 ENST00000588188.6
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr1_+_248095184 0.68 ENST00000358120.3
ENST00000641893.1
OR2L13
olfactory receptor family 2 subfamily L member 13
chr9_-_104599413 0.68 ENST00000374779.3
OR13C5
olfactory receptor family 13 subfamily C member 5
chr1_-_12898270 0.68 ENST00000235347.4
PRAMEF10
PRAME family member 10
chr18_-_36798482 0.68 ENST00000590258.2
TPGS2
tubulin polyglutamylase complex subunit 2
chr7_-_14903319 0.68 ENST00000403951.6
DGKB
diacylglycerol kinase beta
chr11_-_4288083 0.67 ENST00000638166.1
SSU72P4
SSU72 pseudogene 4
chr4_-_185810894 0.65 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
SORBS2
sorbin and SH3 domain containing 2
chr11_-_41459592 0.65 ENST00000528697.6
ENST00000530763.5
LRRC4C
leucine rich repeat containing 4C
chr11_-_133956754 0.65 ENST00000321016.12
IGSF9B
immunoglobulin superfamily member 9B
chr2_+_86106217 0.64 ENST00000409783.6
ENST00000254630.12
ENST00000627371.1
PTCD3
pentatricopeptide repeat domain 3
chr2_-_68871382 0.64 ENST00000295379.2
BMP10
bone morphogenetic protein 10
chr12_-_89656051 0.64 ENST00000261173.6
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr5_+_69217721 0.63 ENST00000256441.5
MRPS36
mitochondrial ribosomal protein S36
chr19_-_7021431 0.63 ENST00000636986.2
ENST00000637800.1
MBD3L2B
methyl-CpG binding domain protein 3 like 2B
chr15_-_26629083 0.63 ENST00000400188.7
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
chr2_+_165572329 0.62 ENST00000342316.8
CSRNP3
cysteine and serine rich nuclear protein 3
chr11_-_48983826 0.62 ENST00000649162.1
TRIM51GP
tripartite motif-containing 51G, pseudogene
chr1_-_165445088 0.61 ENST00000359842.10
RXRG
retinoid X receptor gamma
chr8_-_17002327 0.61 ENST00000180166.6
FGF20
fibroblast growth factor 20
chr6_+_72366730 0.60 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr21_+_42199686 0.60 ENST00000398457.6
ABCG1
ATP binding cassette subfamily G member 1
chr1_-_220046432 0.60 ENST00000609181.5
ENST00000366923.8
EPRS1
glutamyl-prolyl-tRNA synthetase 1
chr2_-_88861258 0.60 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr19_+_7030578 0.60 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3 like 5
chr4_-_69787955 0.59 ENST00000512870.1
SULT1B1
sulfotransferase family 1B member 1
chr11_+_89924064 0.59 ENST00000623787.3
TRIM49D2
tripartite motif containing 49D2
chr11_-_123654581 0.58 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
SCN3B
sodium voltage-gated channel beta subunit 3
chr15_+_62561361 0.58 ENST00000561311.5
TLN2
talin 2
chr16_-_57946602 0.57 ENST00000564654.1
CNGB1
cyclic nucleotide gated channel subunit beta 1
chr19_+_7049321 0.57 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3 like 2
chr5_+_31532277 0.57 ENST00000507818.6
ENST00000325366.14
C5orf22
chromosome 5 open reading frame 22
chr1_+_74198310 0.55 ENST00000472069.1
FPGT
fucose-1-phosphate guanylyltransferase
chr19_-_6393205 0.55 ENST00000595047.5
GTF2F1
general transcription factor IIF subunit 1
chr11_+_99021066 0.54 ENST00000527185.5
ENST00000528682.5
CNTN5
contactin 5
chr7_+_142462882 0.54 ENST00000454561.2
TRBV5-4
T cell receptor beta variable 5-4
chr5_-_111976925 0.54 ENST00000395634.7
NREP
neuronal regeneration related protein
chr5_+_17610496 0.53 ENST00000503184.2
TAF11L12
TATA-box binding protein associated factor 11 like 12
chr5_-_88731827 0.53 ENST00000627170.2
MEF2C
myocyte enhancer factor 2C
chr11_-_123654939 0.53 ENST00000657191.1
SCN3B
sodium voltage-gated channel beta subunit 3
chr4_-_75724386 0.53 ENST00000677606.1
ENST00000678798.1
ENST00000677970.1
ENST00000677620.1
ENST00000679281.1
ENST00000677333.1
ENST00000676470.1
ENST00000499709.3
ENST00000511868.6
ENST00000678971.1
ENST00000677265.1
ENST00000677952.1
ENST00000678122.1
ENST00000678100.1
ENST00000678062.1
ENST00000676666.1
G3BP2
G3BP stress granule assembly factor 2
chr6_-_55579178 0.53 ENST00000308161.8
ENST00000398661.6
ENST00000274901.9
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1
chr1_-_12947580 0.52 ENST00000376189.5
PRAMEF6
PRAME family member 6
chr11_+_5351508 0.52 ENST00000380219.1
OR51B6
olfactory receptor family 51 subfamily B member 6
chr11_+_55262152 0.52 ENST00000417545.5
TRIM48
tripartite motif containing 48
chr3_-_165196689 0.52 ENST00000241274.3
SLITRK3
SLIT and NTRK like family member 3
chr3_+_45886501 0.52 ENST00000395963.2
CCR9
C-C motif chemokine receptor 9
chr4_-_185813121 0.52 ENST00000456060.5
SORBS2
sorbin and SH3 domain containing 2
chr15_+_70936487 0.52 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr8_-_12134099 0.51 ENST00000530447.5
USP17L7
ubiquitin specific peptidase 17 like family member 7
chr2_+_1484663 0.51 ENST00000446278.5
ENST00000469607.3
TPO
thyroid peroxidase
chr11_-_4242640 0.51 ENST00000640805.1
SSU72P2
SSU72 pseudogene 2
chr11_-_13496018 0.50 ENST00000529816.1
PTH
parathyroid hormone
chr1_-_13201409 0.50 ENST00000625019.3
PRAMEF13
PRAME family member 13
chr1_+_13303539 0.50 ENST00000437300.2
PRAMEF33
PRAME family member 33
chr12_+_120302316 0.50 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr1_-_12886201 0.50 ENST00000235349.6
PRAMEF4
PRAME family member 4
chr16_-_21211566 0.49 ENST00000574091.6
ZP2
zona pellucida glycoprotein 2
chr10_-_49188312 0.49 ENST00000453436.5
ENST00000474718.5
TMEM273
transmembrane protein 273
chr1_-_12831410 0.48 ENST00000619922.1
PRAMEF11
PRAME family member 11
chr11_-_4339244 0.48 ENST00000524542.2
SSU72P7
SSU72 pseudogene 7
chr17_+_68525795 0.48 ENST00000592800.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr19_-_7058640 0.48 ENST00000333843.8
MBD3L3
methyl-CpG binding domain protein 3 like 3
chr8_+_91101832 0.48 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr19_-_2090132 0.47 ENST00000591326.5
MOB3A
MOB kinase activator 3A
chr12_-_89656093 0.47 ENST00000359142.7
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr4_+_107989880 0.47 ENST00000309522.8
ENST00000403312.6
ENST00000638559.1
ENST00000682373.1
HADH
hydroxyacyl-CoA dehydrogenase
chr12_+_12725897 0.46 ENST00000326765.10
APOLD1
apolipoprotein L domain containing 1
chr1_-_12945416 0.46 ENST00000415464.6
PRAMEF6
PRAME family member 6
chr1_-_207052980 0.46 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr2_+_197516039 0.46 ENST00000448447.6
ENST00000323303.9
ENST00000409360.1
MOB4
MOB family member 4, phocein
chr18_-_72865680 0.46 ENST00000397929.5
NETO1
neuropilin and tolloid like 1
chr11_+_99020940 0.45 ENST00000524871.6
CNTN5
contactin 5
chr8_-_81695045 0.45 ENST00000518568.3
SLC10A5
solute carrier family 10 member 5
chr17_-_4263847 0.45 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr9_+_136982993 0.45 ENST00000408973.3
LCNL1
lipocalin like 1
chr4_+_653171 0.45 ENST00000488061.5
ENST00000429163.6
PDE6B
phosphodiesterase 6B
chr13_+_57147488 0.44 ENST00000377930.1
PRR20B
proline rich 20B
chr12_-_6635938 0.44 ENST00000329858.9
LPAR5
lysophosphatidic acid receptor 5
chr7_+_124476371 0.44 ENST00000473520.1
SSU72P8
SSU72 pseudogene 8
chr9_-_6008469 0.44 ENST00000399933.8
KIAA2026
KIAA2026
chr6_-_55579160 0.44 ENST00000370850.6
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1
chr2_-_196809352 0.44 ENST00000342506.4
C2orf66
chromosome 2 open reading frame 66
chr11_-_55607645 0.44 ENST00000641580.1
OR4C11
olfactory receptor family 4 subfamily C member 11
chr16_-_57186053 0.44 ENST00000565760.5
ENST00000570184.1
ENST00000562324.5
PSME3IP1
proteasome activator subunit 3 interacting protein 1
chr12_-_109996216 0.43 ENST00000551209.5
ENST00000550186.5
GIT2
GIT ArfGAP 2
chr11_+_4233288 0.43 ENST00000639584.1
SSU72P5
SSU72 pseudogene 5
chr9_-_28670285 0.43 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr1_+_74198230 0.43 ENST00000557284.7
ENST00000370899.7
ENST00000370895.5
ENST00000534632.5
ENST00000370893.1
ENST00000467578.7
ENST00000370894.9
ENST00000482102.2
ENST00000370898.9
ENST00000534056.5
FPGT-TNNI3K
FPGT
FPGT-TNNI3K readthrough
fucose-1-phosphate guanylyltransferase
chr10_+_70093626 0.43 ENST00000678195.1
MACROH2A2
macroH2A.2 histone
chrX_+_150699208 0.43 ENST00000436701.5
ENST00000438018.5
MTMR1
myotubularin related protein 1
chr15_-_92809798 0.42 ENST00000557398.2
FAM174B
family with sequence similarity 174 member B
chr11_-_117817500 0.42 ENST00000525836.1
DSCAML1
DS cell adhesion molecule like 1
chr5_-_31532039 0.42 ENST00000511367.6
ENST00000344624.8
ENST00000513349.5
DROSHA
drosha ribonuclease III
chr1_-_165445220 0.42 ENST00000619224.1
RXRG
retinoid X receptor gamma
chr2_-_212124901 0.41 ENST00000402597.6
ERBB4
erb-b2 receptor tyrosine kinase 4
chr12_-_119877300 0.41 ENST00000392521.7
CIT
citron rho-interacting serine/threonine kinase
chr7_-_126533850 0.41 ENST00000444921.3
GRM8
glutamate metabotropic receptor 8
chr2_-_88861920 0.41 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr19_-_6393131 0.41 ENST00000394456.10
GTF2F1
general transcription factor IIF subunit 1
chr14_+_22147988 0.41 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr11_+_123902167 0.40 ENST00000641687.1
OR8D4
olfactory receptor family 8 subfamily D member 4
chr2_+_108607140 0.40 ENST00000410093.5
LIMS1
LIM zinc finger domain containing 1
chrX_+_53094133 0.40 ENST00000604062.6
KANTR
KDM5C adjacent transcript
chr2_-_197198034 0.40 ENST00000328737.6
ANKRD44
ankyrin repeat domain 44
chr15_+_43330646 0.40 ENST00000562188.7
ENST00000428046.7
ENST00000389651.8
ADAL
adenosine deaminase like
chr6_+_121437378 0.40 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chrX_+_65488735 0.40 ENST00000338957.4
ZC3H12B
zinc finger CCCH-type containing 12B
chr8_-_12138845 0.39 ENST00000333796.4
USP17L2
ubiquitin specific peptidase 17 like family member 2
chr1_-_248559516 0.39 ENST00000328570.6
OR2T29
olfactory receptor family 2 subfamily T member 29
chr16_-_70289480 0.39 ENST00000261772.13
ENST00000675953.1
ENST00000675691.1
ENST00000675133.1
ENST00000674512.1
ENST00000675045.1
ENST00000675853.1
ENST00000565361.3
ENST00000674963.1
ENST00000674691.1
AARS1
alanyl-tRNA synthetase 1
chr17_-_41397600 0.39 ENST00000251645.3
KRT31
keratin 31
chr16_-_29995601 0.39 ENST00000279392.8
ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chr6_-_73225465 0.39 ENST00000370388.4
KHDC1L
KH domain containing 1 like
chr7_+_142535763 0.38 ENST00000614171.1
TRBV13
T cell receptor beta variable 13
chr12_-_118359639 0.38 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr1_+_13254212 0.38 ENST00000622421.2
PRAMEF5
PRAME family member 5
chr11_+_118359572 0.37 ENST00000252108.8
ENST00000431736.6
UBE4A
ubiquitination factor E4A
chr11_+_55883297 0.37 ENST00000449290.6
TRIM51
tripartite motif-containing 51
chr11_+_24496988 0.37 ENST00000336930.11
LUZP2
leucine zipper protein 2
chr19_-_14674829 0.37 ENST00000443157.6
ENST00000253673.6
ADGRE3
adhesion G protein-coupled receptor E3
chr20_-_35411963 0.37 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
UQCC1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr8_-_53251412 0.36 ENST00000520287.5
OPRK1
opioid receptor kappa 1
chr9_+_105662457 0.36 ENST00000334077.6
TAL2
TAL bHLH transcription factor 2
chr4_-_75724362 0.36 ENST00000677583.1
G3BP2
G3BP stress granule assembly factor 2
chr1_+_50103903 0.36 ENST00000371827.5
ELAVL4
ELAV like RNA binding protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of DUXA

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.3 1.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 1.3 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.3 0.9 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 2.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 1.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.3 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 0.6 GO:0009720 detection of hormone stimulus(GO:0009720)
0.2 0.4 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 2.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 0.5 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 3.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 0.5 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.5 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.4 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 1.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 1.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.4 GO:1903937 response to acrylamide(GO:1903937)
0.1 0.4 GO:0060003 copper ion export(GO:0060003)
0.1 0.4 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.5 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 0.9 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 2.0 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.3 GO:0048561 establishment of organ orientation(GO:0048561)
0.1 1.2 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.3 GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation(GO:0070145)
0.1 1.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.3 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.6 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.4 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 2.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.3 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 4.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.4 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.5 GO:0007343 egg activation(GO:0007343) negative regulation of fertilization(GO:0060467)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 6.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.9 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.4 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.6 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 1.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 2.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.4 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 1.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.1 0.2 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.2 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:1990172 CVT pathway(GO:0032258) G-protein coupled receptor catabolic process(GO:1990172)
0.0 0.5 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.6 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.2 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.7 GO:2000628 production of siRNA involved in RNA interference(GO:0030422) regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 1.0 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.3 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 1.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 1.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 6.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 1.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 1.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 1.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.6 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0034505 tooth mineralization(GO:0034505)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 0.7 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 1.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 3.4 GO:0036449 microtubule minus-end(GO:0036449)
0.2 4.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.1 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.3 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.1 2.4 GO:0005916 fascia adherens(GO:0005916)
0.1 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.7 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 1.0 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.4 GO:0031045 dense core granule(GO:0031045)
0.0 2.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.0 1.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0031417 NatC complex(GO:0031417)
0.0 2.2 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 7.2 GO:0030018 Z disc(GO:0030018)
0.0 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 7.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0030017 sarcomere(GO:0030017)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.2 1.0 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.2 1.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 1.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 2.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 1.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 4.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.5 GO:0047708 biotinidase activity(GO:0047708)
0.1 1.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0004008 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.1 0.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 1.0 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 4.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0050560 aspartate-tRNA ligase activity(GO:0004815) aspartate-tRNA(Asn) ligase activity(GO:0050560)
0.1 0.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.7 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.4 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 2.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 1.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.6 GO:0005223 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0031433 telethonin binding(GO:0031433)
0.1 1.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0032190 acrosin binding(GO:0032190)
0.0 1.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 1.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104) heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 5.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 5.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 6.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 2.8 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 2.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 1.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 4.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport