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Illumina Body Map 2 (GSE30611)

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Results for E2F2_E2F5

Z-value: 1.46

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Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.7 E2F transcription factor 2
ENSG00000133740.11 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F2hg38_v1_chr1_-_23531206_235312410.551.2e-03Click!
E2F5hg38_v1_chr8_+_85209213_852092700.421.7e-02Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_4909430 4.08 ENST00000620565.4
ENST00000613817.4
ENST00000624301.3
ENST00000650932.1
ubiquitin like with PHD and ring finger domains 1
chr2_+_173354820 3.83 ENST00000347703.7
ENST00000410101.7
ENST00000410019.3
ENST00000306721.8
cell division cycle associated 7
chr1_-_25905989 3.16 ENST00000399728.5
stathmin 1
chr1_-_25906411 3.06 ENST00000455785.7
stathmin 1
chr20_-_33686371 3.02 ENST00000343380.6
E2F transcription factor 1
chr1_-_23531206 2.78 ENST00000361729.3
E2F transcription factor 2
chr1_-_25906931 2.63 ENST00000357865.6
stathmin 1
chr10_+_110567666 2.56 ENST00000361804.5
structural maintenance of chromosomes 3
chr15_+_32615501 2.49 ENST00000361627.8
ENST00000567348.5
ENST00000563864.5
ENST00000543522.5
Rho GTPase activating protein 11A
chr20_-_37095985 2.47 ENST00000344359.7
ENST00000373664.8
RB transcriptional corepressor like 1
chr3_+_127598400 2.47 ENST00000265056.12
minichromosome maintenance complex component 2
chr22_+_35400115 2.39 ENST00000382011.9
ENST00000216122.9
ENST00000416905.1
minichromosome maintenance complex component 5
chr1_-_25906457 2.36 ENST00000426559.6
stathmin 1
chr10_-_73874568 2.01 ENST00000322635.7
ENST00000322680.7
ENST00000394762.7
ENST00000680035.1
calcium/calmodulin dependent protein kinase II gamma
chr9_-_111038037 1.95 ENST00000374431.7
lysophosphatidic acid receptor 1
chr10_-_73874502 1.93 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
calcium/calmodulin dependent protein kinase II gamma
chr1_-_35769928 1.85 ENST00000373220.7
ENST00000520551.1
claspin
chr7_+_94656325 1.83 ENST00000482108.1
ENST00000488574.5
ENST00000612748.1
ENST00000613043.1
paternally expressed 10
chr9_-_111038425 1.82 ENST00000441240.1
ENST00000683809.1
lysophosphatidic acid receptor 1
chr10_-_73874461 1.78 ENST00000305762.11
calcium/calmodulin dependent protein kinase II gamma
chr1_-_120069616 1.73 ENST00000652302.1
ENST00000652737.1
ENST00000256646.7
notch receptor 2
chr20_+_25407657 1.72 ENST00000262460.5
GINS complex subunit 1
chr8_+_93916882 1.70 ENST00000297598.5
ENST00000520728.5
ENST00000518107.5
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr12_-_44876294 1.69 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr2_+_15940537 1.65 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr16_-_2980406 1.64 ENST00000431515.6
ENST00000574385.5
ENST00000576268.1
ENST00000574730.5
ENST00000262300.13
ENST00000575632.5
ENST00000573944.5
protein kinase, membrane associated tyrosine/threonine 1
chr15_+_40695129 1.57 ENST00000423169.6
ENST00000557850.5
ENST00000382643.7
ENST00000267868.8
ENST00000645673.2
RAD51 recombinase
chr22_+_41699492 1.57 ENST00000401548.8
ENST00000540833.1
meiotic double-stranded break formation protein 1
chr3_-_48188356 1.55 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
cell division cycle 25A
chr2_-_17753792 1.53 ENST00000448223.7
ENST00000621152.4
ENST00000351948.8
structural maintenance of chromosomes 6
chr9_-_111038061 1.51 ENST00000358883.8
lysophosphatidic acid receptor 1
chr2_+_27275466 1.47 ENST00000404433.5
ENST00000406962.1
DnaJ heat shock protein family (Hsp40) member C5 gamma
chr8_-_97277890 1.45 ENST00000322128.5
TSPY like 5
chr20_+_2101807 1.43 ENST00000381482.8
serine/threonine kinase 35
chr2_-_234497035 1.42 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr1_-_35769958 1.42 ENST00000251195.9
ENST00000318121.8
claspin
chr2_-_27275340 1.39 ENST00000424577.5
ENST00000426569.1
solute carrier family 30 member 3
chr5_-_80654956 1.32 ENST00000439211.7
dihydrofolate reductase
chr22_-_38570167 1.29 ENST00000216024.7
ENST00000616615.4
DNA meiotic recombinase 1
chr5_-_80654552 1.29 ENST00000511032.5
ENST00000504396.1
ENST00000505337.5
dihydrofolate reductase
chr10_+_94545852 1.29 ENST00000394036.5
ENST00000394045.5
helicase, lymphoid specific
chr19_-_56840661 1.29 ENST00000649735.1
ENST00000593695.5
ENST00000599577.5
ENST00000594389.1
ENST00000648694.1
ENST00000326441.15
ENST00000649680.1
ENST00000649876.1
ENST00000650632.1
ENST00000650102.1
ENST00000647621.1
ENST00000598410.5
ENST00000649233.1
ENST00000593711.6
ENST00000629319.2
ENST00000599935.5
paternally expressed 3
zinc finger imprinted 2
chr11_+_65041203 1.29 ENST00000652489.1
ENST00000674184.1
SAC3 domain containing 1
chr3_+_16884942 1.27 ENST00000615277.5
phospholipase C like 2
chr13_-_41194485 1.26 ENST00000379483.4
kelch repeat and BTB domain containing 7
chr10_+_94545777 1.25 ENST00000348459.10
ENST00000419900.5
ENST00000630929.2
helicase, lymphoid specific
chr2_+_27275429 1.22 ENST00000420191.5
ENST00000296097.8
DnaJ heat shock protein family (Hsp40) member C5 gamma
chr16_-_2980282 1.22 ENST00000572619.1
ENST00000574415.5
ENST00000440027.6
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr2_-_27263034 1.22 ENST00000233535.9
solute carrier family 30 member 3
chr11_+_65040895 1.20 ENST00000531072.1
ENST00000398846.6
SAC3 domain containing 1
chr20_-_5950463 1.17 ENST00000203001.7
ENST00000453074.6
tRNA methyltransferase 6
chr15_-_66356672 1.16 ENST00000261881.9
TIMELESS interacting protein
chr3_+_44761765 1.16 ENST00000326047.9
kinesin family member 15
chr22_+_41998780 1.15 ENST00000328823.13
WBP2 N-terminal like
chr12_-_132687307 1.14 ENST00000535270.5
ENST00000320574.10
DNA polymerase epsilon, catalytic subunit
chrX_+_102651366 1.13 ENST00000415986.5
ENST00000444152.5
ENST00000361600.9
G protein-coupled receptor associated sorting protein 1
chr15_+_40695423 1.13 ENST00000526763.6
ENST00000532743.6
RAD51 recombinase
chr2_-_96034916 1.11 ENST00000359548.8
ENST00000439254.1
ENST00000453542.5
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr2_-_17753757 1.11 ENST00000446852.5
structural maintenance of chromosomes 6
chr6_+_89829931 1.06 ENST00000551025.4
caspase 8 associated protein 2
chr6_+_89829888 1.06 ENST00000552401.5
ENST00000419040.6
caspase 8 associated protein 2
chr7_-_100101333 1.06 ENST00000303887.10
minichromosome maintenance complex component 7
chr14_-_49688201 1.06 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chr1_+_120723939 1.05 ENST00000624419.2
ENST00000652763.1
ENST00000620612.5
notch 2 N-terminal like R (pseudogene)
NBPF member 26
chr10_-_73247241 1.04 ENST00000372950.6
DnaJ heat shock protein family (Hsp40) member C9
chr9_-_120877167 1.03 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr4_+_153344671 1.02 ENST00000240488.8
meiotic nuclear divisions 1
chr11_-_74731385 1.02 ENST00000622063.4
ENST00000376332.8
chordin like 2
chr4_+_70993542 1.02 ENST00000504730.5
ENST00000504952.1
ENST00000286648.10
deoxycytidine kinase
chr3_-_56683218 1.00 ENST00000355628.9
ENST00000683822.1
transcription activation suppressor
chr12_-_44875647 0.98 ENST00000395487.6
neural EGFL like 2
chr19_-_36214645 0.98 ENST00000304116.10
zinc finger protein 565
chr7_+_120950763 0.98 ENST00000339121.9
ENST00000315870.10
ENST00000445699.5
inhibitor of growth family member 3
chr22_-_38570118 0.98 ENST00000439567.5
DNA meiotic recombinase 1
chr7_-_158704740 0.98 ENST00000409339.3
ENST00000356309.8
ENST00000409423.5
non-SMC condensin II complex subunit G2
chr3_-_133661896 0.97 ENST00000260810.10
DNA topoisomerase II binding protein 1
chr2_-_218568291 0.97 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr7_-_148884159 0.94 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr19_-_10194898 0.92 ENST00000359526.9
ENST00000679103.1
ENST00000676610.1
ENST00000678804.1
ENST00000679313.1
ENST00000677946.1
DNA methyltransferase 1
chr9_+_79571767 0.91 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr20_-_62407274 0.91 ENST00000279101.9
Cdk5 and Abl enzyme substrate 2
chr12_+_27780224 0.89 ENST00000381271.7
kelch like family member 42
chr5_+_43120883 0.88 ENST00000515326.5
ENST00000682664.1
zinc finger protein 131
chr2_-_135876382 0.87 ENST00000264156.3
minichromosome maintenance complex component 6
chr5_-_11904417 0.85 ENST00000304623.13
catenin delta 2
chr1_+_151070740 0.84 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr2_+_27275461 0.83 ENST00000402462.5
DnaJ heat shock protein family (Hsp40) member C5 gamma
chr2_+_46941199 0.82 ENST00000319190.11
ENST00000394850.6
tetratricopeptide repeat domain 7A
chr10_-_56361235 0.81 ENST00000373944.8
ENST00000361148.6
ENST00000395405.5
ZW10 interacting kinetochore protein
chrX_+_24693879 0.81 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
DNA polymerase alpha 1, catalytic subunit
chr8_-_119855838 0.81 ENST00000313655.5
DNA replication and sister chromatid cohesion 1
chr17_-_7294592 0.80 ENST00000007699.10
Y-box binding protein 2
chr8_+_47961028 0.80 ENST00000650216.1
minichromosome maintenance complex component 4
chr17_-_59106801 0.80 ENST00000393065.6
ENST00000262294.12
ENST00000393066.7
tripartite motif containing 37
chr4_-_129093454 0.78 ENST00000281142.10
ENST00000511426.5
sodium channel and clathrin linker 1
chr3_+_10026409 0.78 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chrX_+_102651476 0.77 ENST00000537097.2
G protein-coupled receptor associated sorting protein 1
chr9_-_35079923 0.77 ENST00000378643.8
ENST00000448890.1
FA complementation group G
chr2_+_17754116 0.77 ENST00000381254.7
ENST00000524465.5
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr11_-_74731148 0.77 ENST00000263671.9
ENST00000528789.1
chordin like 2
chr16_+_88803776 0.76 ENST00000301019.9
chromatin licensing and DNA replication factor 1
chr8_+_47960883 0.76 ENST00000648407.1
ENST00000649838.1
ENST00000649919.1
ENST00000262105.6
ENST00000649973.1
minichromosome maintenance complex component 4
chrX_+_76427666 0.75 ENST00000361470.4
MAGE family member E1
chr2_+_10123171 0.73 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr17_+_30831944 0.73 ENST00000321990.5
ATPase family AAA domain containing 5
chr7_-_6009019 0.73 ENST00000382321.5
ENST00000265849.12
PMS1 homolog 2, mismatch repair system component
chr19_+_49361783 0.70 ENST00000594268.1
dickkopf like acrosomal protein 1
chr19_-_10568968 0.70 ENST00000393599.3
cyclin dependent kinase inhibitor 2D
chr19_-_13906062 0.70 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr7_-_148884266 0.70 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr5_+_43121504 0.70 ENST00000509156.5
ENST00000508259.5
ENST00000306938.8
zinc finger protein 131
chr3_+_14947680 0.69 ENST00000435454.5
ENST00000323373.10
nuclear receptor subfamily 2 group C member 2
chr1_-_146229000 0.69 ENST00000612520.2
ENST00000579793.6
ENST00000362074.7
NBPF member 10
notch 2 N-terminal like A
chr19_-_10569022 0.69 ENST00000335766.2
cyclin dependent kinase inhibitor 2D
chr1_+_53459391 0.69 ENST00000371445.3
DMRT like family B with proline rich C-terminal 1
chr10_+_100912955 0.69 ENST00000370271.7
ENST00000238961.9
ENST00000370269.3
ENST00000609386.1
SMC5-SMC6 complex localization factor 2
chr1_-_180502536 0.68 ENST00000367595.4
acyl-CoA binding domain containing 6
chr1_-_202710428 0.68 ENST00000367268.5
synaptotagmin 2
chr15_+_44427793 0.67 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTD small phosphatase like 2
chr6_+_31739948 0.67 ENST00000375755.8
ENST00000425703.5
ENST00000375750.9
ENST00000375703.7
ENST00000375740.7
mutS homolog 5
chr17_+_44656429 0.67 ENST00000409122.7
meiosis specific with coiled-coil domain
chr2_+_47783172 0.66 ENST00000540021.6
mutS homolog 6
chr7_-_100428657 0.66 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr20_+_5950630 0.65 ENST00000378883.5
ENST00000378896.7
ENST00000378886.6
ENST00000610722.4
minichromosome maintenance 8 homologous recombination repair factor
chr6_+_24775413 0.65 ENST00000378054.6
ENST00000620958.4
ENST00000476555.5
geminin DNA replication inhibitor
chr7_-_6009072 0.65 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS1 homolog 2, mismatch repair system component
chr7_-_105876575 0.64 ENST00000318724.8
ENST00000419735.8
ataxin 7 like 1
chr12_-_44875980 0.64 ENST00000548826.5
neural EGFL like 2
chr5_+_94618653 0.63 ENST00000265140.10
ENST00000504099.5
SMC5-SMC6 complex localization factor 1
chr12_+_80707625 0.63 ENST00000228641.4
myogenic factor 6
chr6_-_27132750 0.62 ENST00000607124.1
ENST00000339812.3
H2B clustered histone 11
chr9_+_97983332 0.62 ENST00000339399.5
acidic nuclear phosphoprotein 32 family member B
chr12_-_48105808 0.62 ENST00000448372.5
SUMO specific peptidase 1
chrX_-_63755032 0.62 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr19_-_10333512 0.62 ENST00000617231.5
ENST00000611074.4
ENST00000615032.4
ribonucleoprotein, PTB binding 1
chr5_+_134526100 0.62 ENST00000395003.5
jade family PHD finger 2
chrX_+_47232866 0.61 ENST00000218348.7
ENST00000377107.7
ubiquitin specific peptidase 11
chr4_-_129093377 0.60 ENST00000506368.5
ENST00000439369.6
ENST00000503215.5
sodium channel and clathrin linker 1
chr1_-_151146611 0.60 ENST00000341697.7
ENST00000368914.8
semaphorin 6C
chr16_-_85688912 0.59 ENST00000253462.8
GINS complex subunit 2
chr5_+_43121596 0.59 ENST00000505606.6
ENST00000509634.5
ENST00000509341.5
zinc finger protein 131
chr2_+_218568558 0.58 ENST00000627282.2
ENST00000542068.5
CCR4-NOT transcription complex subunit 9
chr12_-_12696171 0.58 ENST00000651487.1
ENST00000332427.6
ENST00000540796.5
G protein-coupled receptor 19
chr7_+_120951116 0.58 ENST00000431467.1
inhibitor of growth family member 3
chrX_-_136767322 0.57 ENST00000370620.5
Rac/Cdc42 guanine nucleotide exchange factor 6
chr22_-_28741783 0.56 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr3_-_14178615 0.56 ENST00000511155.1
XPC complex subunit, DNA damage recognition and repair factor
chr6_+_27133032 0.55 ENST00000359193.3
H2A clustered histone 11
chr15_-_70096604 0.55 ENST00000559048.5
ENST00000560939.5
ENST00000440567.7
ENST00000557907.5
ENST00000558379.5
ENST00000559929.5
TLE family member 3, transcriptional corepressor
chr2_+_47403116 0.55 ENST00000645506.1
ENST00000406134.5
ENST00000233146.7
mutS homolog 2
chr2_+_218568865 0.55 ENST00000295701.9
CCR4-NOT transcription complex subunit 9
chr2_-_144517506 0.54 ENST00000431672.4
ENST00000558170.6
zinc finger E-box binding homeobox 2
chr12_-_48106042 0.53 ENST00000551798.1
ENST00000549518.6
SUMO specific peptidase 1
chr3_+_134795248 0.53 ENST00000398015.8
EPH receptor B1
chr16_+_1989949 0.53 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr17_-_42745025 0.53 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr13_+_45120493 0.53 ENST00000340473.8
general transcription factor IIF subunit 2
chr1_+_35573308 0.52 ENST00000373235.4
transcription factor AP-2 epsilon
chr1_-_27914513 0.52 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr1_+_149390612 0.52 ENST00000650865.1
ENST00000652191.1
ENST00000621744.4
notch 2 N-terminal like C
novel protein, identical to neuroblastoma breakpoint family, member 19 NBPF19
chr16_+_2969548 0.51 ENST00000572687.1
progestin and adipoQ receptor family member 4
chr1_-_47314089 0.51 ENST00000360380.7
ENST00000371877.8
ENST00000447475.7
STIL centriolar assembly protein
chr9_+_104094260 0.51 ENST00000286398.11
ENST00000440179.5
ENST00000374793.8
structural maintenance of chromosomes 2
chrX_+_132023294 0.51 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr8_-_94553444 0.51 ENST00000297591.10
ENST00000421249.2
vir like m6A methyltransferase associated
chr1_-_91021996 0.51 ENST00000337393.10
zinc finger protein 644
chr15_-_40108861 0.50 ENST00000354670.9
ENST00000559701.5
ENST00000557870.1
ENST00000558774.5
Bcl2 modifying factor
chr2_+_237798764 0.50 ENST00000316997.9
RNA binding motif protein 44
chrX_+_123962040 0.50 ENST00000435215.5
stromal antigen 2
chr2_+_47783082 0.50 ENST00000614496.4
ENST00000622629.4
ENST00000234420.11
ENST00000616033.4
ENST00000673637.1
mutS homolog 6
chr3_+_44761831 0.49 ENST00000481166.6
kinesin family member 15
chr6_+_24774925 0.49 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chr4_-_129093548 0.49 ENST00000503401.1
sodium channel and clathrin linker 1
chr2_-_144517663 0.49 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr3_-_53046031 0.49 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr9_+_104094557 0.48 ENST00000374787.7
structural maintenance of chromosomes 2
chr13_-_41132728 0.47 ENST00000379485.2
kelch repeat and BTB domain containing 6
chr10_+_60778331 0.47 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
cyclin dependent kinase 1
chr5_+_36876731 0.47 ENST00000282516.13
ENST00000448238.2
NIPBL cohesin loading factor
chr19_+_2236816 0.46 ENST00000221494.10
splicing factor 3a subunit 2
chr6_+_83859640 0.46 ENST00000369679.4
ENST00000369681.10
cytochrome b5 reductase 4
chr17_+_29390326 0.46 ENST00000261716.8
TAO kinase 1
chr4_+_153344633 0.46 ENST00000622785.4
meiotic nuclear divisions 1
chr1_-_151146643 0.46 ENST00000613223.1
semaphorin 6C
chr12_-_48852133 0.46 ENST00000552512.5
ENST00000551468.1
DEAD-box helicase 23
chr19_-_12919256 0.45 ENST00000293695.8
synaptonemal complex central element protein 2
chr8_-_131040890 0.45 ENST00000286355.10
adenylate cyclase 8
chr15_+_44427591 0.45 ENST00000558791.5
ENST00000260327.9
CTD small phosphatase like 2
chr11_-_64972023 0.45 ENST00000530444.5
membrane anchored junction protein
chr16_+_30395400 0.44 ENST00000320159.2
ENST00000613509.2
zinc finger protein 48
chr10_+_59176600 0.44 ENST00000373880.9
phytanoyl-CoA 2-hydroxylase interacting protein like
chr13_+_97976632 0.43 ENST00000490680.5
ENST00000403772.8
importin 5
chr1_+_65992389 0.43 ENST00000423207.6
phosphodiesterase 4B
chr8_+_93916849 0.43 ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_+_25272502 0.43 ENST00000328664.9
Rh blood group D antigen
chr17_-_44503369 0.43 ENST00000585614.1
ENST00000591680.6
G-patch domain containing 8
chr3_+_14947568 0.42 ENST00000413118.5
ENST00000425241.5
nuclear receptor subfamily 2 group C member 2
chr1_-_42335189 0.42 ENST00000361776.5
ENST00000445886.5
ENST00000361346.6
forkhead box J3
chr13_-_78603539 0.42 ENST00000377208.7
POU class 4 homeobox 1
chr7_-_100101915 0.42 ENST00000621318.4
ENST00000343023.10
minichromosome maintenance complex component 7

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.1 5.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.9 2.6 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.8 2.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.8 11.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.6 9.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 1.9 GO:1990172 G-protein coupled receptor catabolic process(GO:1990172)
0.6 2.2 GO:0006272 leading strand elongation(GO:0006272)
0.5 1.6 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4 1.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.4 2.6 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.4 0.4 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 4.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.3 1.3 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.3 1.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.3 1.9 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.3 3.8 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 1.5 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.3 0.8 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.3 0.8 GO:0009386 translational attenuation(GO:0009386)
0.3 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 0.9 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.2 2.3 GO:0042148 strand invasion(GO:0042148)
0.2 0.9 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.2 0.6 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.2 6.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 2.9 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 2.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 3.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 1.5 GO:0048478 replication fork protection(GO:0048478)
0.2 0.6 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.2 GO:0000076 DNA replication checkpoint(GO:0000076)
0.2 1.0 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.2 2.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.2 2.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 2.8 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 2.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 1.4 GO:0048102 autophagic cell death(GO:0048102)
0.1 1.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.4 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 1.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.9 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 2.3 GO:0090220 meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 1.0 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 2.5 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 0.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 1.0 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.7 GO:0051026 chiasma assembly(GO:0051026)
0.1 1.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.7 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.5 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 1.0 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 4.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.8 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.6 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.2 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.4 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.8 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.9 GO:0015695 organic cation transport(GO:0015695)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0000732 strand displacement(GO:0000732)
0.0 0.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.7 GO:0031577 spindle checkpoint(GO:0031577)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 1.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.0 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.2 GO:2000828 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.8 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 2.3 GO:0000811 GINS complex(GO:0000811)
0.4 2.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.4 2.1 GO:0032301 MutSalpha complex(GO:0032301)
0.4 6.6 GO:0042555 MCM complex(GO:0042555)
0.4 0.4 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
0.4 2.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 1.8 GO:0035061 interchromatin granule(GO:0035061)
0.3 1.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.3 1.1 GO:0033011 perinuclear theca(GO:0033011)
0.3 0.9 GO:0032116 SMC loading complex(GO:0032116)
0.3 1.7 GO:0005873 plus-end kinesin complex(GO:0005873)
0.2 0.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 1.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.0 GO:0000796 condensin complex(GO:0000796)
0.1 5.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.0 GO:0071942 XPC complex(GO:0071942)
0.1 1.4 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 3.0 GO:0000800 lateral element(GO:0000800)
0.1 1.3 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.1 1.9 GO:0071439 clathrin complex(GO:0071439)
0.1 2.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.4 GO:0072534 perineuronal net(GO:0072534)
0.1 4.2 GO:0005657 replication fork(GO:0005657)
0.1 0.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 5.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 5.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 9.7 GO:0005874 microtubule(GO:0005874)
0.0 2.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 2.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.7 2.6 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.6 3.8 GO:0031493 nucleosomal histone binding(GO:0031493)
0.6 5.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.5 3.0 GO:0036033 mediator complex binding(GO:0036033)
0.4 2.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.4 2.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 3.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 5.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.3 5.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 0.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 2.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 2.0 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.2 5.0 GO:0000150 recombinase activity(GO:0000150)
0.2 2.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 2.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 1.7 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.4 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.0 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.1 0.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 1.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.8 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 3.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 3.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 11.5 GO:0015631 tubulin binding(GO:0015631)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 1.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 5.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 15.8 PID ATR PATHWAY ATR signaling pathway
0.1 5.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 7.2 PID E2F PATHWAY E2F transcription factor network
0.1 2.7 PID ATM PATHWAY ATM pathway
0.0 5.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 5.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.5 2.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 6.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 4.9 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 4.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 7.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 1.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 2.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.7 REACTOME KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 2.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 5.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis