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Illumina Body Map 2 (GSE30611)

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Results for E2F4

Z-value: 0.82

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Transcription factors associated with E2F4

Gene Symbol Gene ID Gene Info
ENSG00000205250.9 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F4hg38_v1_chr16_+_67192116_671922250.451.0e-02Click!

Activity profile of E2F4 motif

Sorted Z-values of E2F4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_23821275 2.31 ENST00000380110.8
ELAV like RNA binding protein 2
chr4_+_1712821 2.16 ENST00000458173.4
transforming acidic coiled-coil containing protein 3
chr1_-_182953132 1.89 ENST00000367547.8
SHC binding and spindle associated 1 like
chr5_+_134115563 1.60 ENST00000517851.5
ENST00000521639.5
ENST00000522375.5
ENST00000378560.8
ENST00000520958.5
ENST00000518915.5
ENST00000395023.5
transcription factor 7
chr17_-_45262084 1.50 ENST00000331780.5
spermatogenesis associated 32
chr9_-_23821809 1.43 ENST00000544538.5
ELAV like RNA binding protein 2
chr12_+_94148553 1.40 ENST00000258526.9
plexin C1
chr22_+_19479826 1.37 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chr20_-_57525123 1.36 ENST00000243914.8
CCCTC-binding factor like
chr17_-_7294592 1.33 ENST00000007699.10
Y-box binding protein 2
chr7_-_100428657 1.31 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr1_-_25859352 1.21 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr20_-_53593829 1.20 ENST00000371471.7
zinc finger protein 217
chr17_+_47733228 1.16 ENST00000177694.2
T-box transcription factor 21
chrY_+_20575716 1.11 ENST00000361365.7
eukaryotic translation initiation factor 1A Y-linked
chr2_-_218568291 1.09 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr11_+_82901698 1.08 ENST00000524921.5
ENST00000528759.5
ENST00000525361.5
ENST00000532764.5
ENST00000532589.5
ENST00000533655.6
ENST00000525388.5
DNA damage induced apoptosis suppressor
chr15_+_44956683 1.07 ENST00000340827.4
telomere repeat binding bouquet formation protein 2
chr8_+_47960883 1.06 ENST00000648407.1
ENST00000649838.1
ENST00000649919.1
ENST00000262105.6
ENST00000649973.1
minichromosome maintenance complex component 4
chr11_-_32435529 1.04 ENST00000448076.9
ENST00000452863.10
WT1 transcription factor
chrY_+_20575792 1.03 ENST00000382772.3
eukaryotic translation initiation factor 1A Y-linked
chr9_+_121074944 1.03 ENST00000373855.7
centriolin
chr12_+_49323236 1.02 ENST00000549275.5
ENST00000551245.5
ENST00000380327.9
ENST00000548311.5
ENST00000257909.8
ENST00000550346.5
ENST00000550709.5
ENST00000549534.1
ENST00000547807.5
ENST00000551567.1
trophinin associated protein
chr15_+_90717321 1.00 ENST00000355112.8
ENST00000681142.1
ENST00000648453.1
ENST00000560509.5
BLM RecQ like helicase
chr2_+_27051637 0.99 ENST00000451003.5
ENST00000360131.5
ENST00000323064.12
ATP/GTP binding protein like 5
chr11_-_32435557 0.95 ENST00000332351.9
WT1 transcription factor
chr3_+_141051339 0.89 ENST00000310546.3
splA/ryanodine receptor domain and SOCS box containing 4
chrX_+_105822531 0.87 ENST00000243300.14
ENST00000536164.5
Nik related kinase
chr2_+_28810816 0.87 ENST00000379579.8
ENST00000334056.10
ENST00000449210.1
speedy/RINGO cell cycle regulator family member A
chr17_+_40287861 0.84 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr22_+_41092585 0.81 ENST00000263253.9
E1A binding protein p300
chr1_+_178725277 0.80 ENST00000324778.5
Ral GEF with PH domain and SH3 binding motif 2
chr9_-_107489754 0.80 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr2_+_71276553 0.80 ENST00000494621.5
ENST00000466975.5
ENST00000410075.5
ENST00000466330.5
zinc finger protein 638
chr6_-_27132750 0.79 ENST00000607124.1
ENST00000339812.3
H2B clustered histone 11
chr10_-_29735787 0.78 ENST00000375400.7
supervillin
chr3_-_51499950 0.78 ENST00000423656.5
ENST00000504652.5
ENST00000684031.1
DDB1 and CUL4 associated factor 1
chr8_+_47961028 0.77 ENST00000650216.1
minichromosome maintenance complex component 4
chr14_+_56118404 0.77 ENST00000267460.9
pellino E3 ubiquitin protein ligase family member 2
chr4_-_173333672 0.76 ENST00000438704.6
high mobility group box 2
chr9_+_128947687 0.76 ENST00000372577.2
nucleoporin 188
chr12_-_48105808 0.76 ENST00000448372.5
SUMO specific peptidase 1
chr2_+_218710821 0.76 ENST00000392102.6
ENST00000457313.5
ENST00000415717.5
tubulin tyrosine ligase like 4
chrX_-_126166273 0.75 ENST00000360028.4
DDB1 and CUL4 associated factor 12 like 2
chr19_-_13906062 0.75 ENST00000591586.5
ENST00000346736.6
break repair meiotic recombinase recruitment factor 1
chr7_-_21945866 0.74 ENST00000356195.9
ENST00000447180.5
ENST00000373934.4
ENST00000406877.8
ENST00000457951.5
cell division cycle associated 7 like
chr2_+_218710931 0.72 ENST00000442769.5
ENST00000424644.1
tubulin tyrosine ligase like 4
chr3_+_155870623 0.71 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr4_+_153344671 0.71 ENST00000240488.8
meiotic nuclear divisions 1
chr7_-_124033042 0.70 ENST00000455783.3
transmembrane protein 229A
chr12_-_48106042 0.70 ENST00000551798.1
ENST00000549518.6
SUMO specific peptidase 1
chr17_+_45161070 0.70 ENST00000593138.6
ENST00000586681.6
HEXIM P-TEFb complex subunit 2
chr9_-_85741874 0.69 ENST00000357081.8
ENST00000337006.8
ENST00000628899.1
ATP/GTP binding protein 1
chr18_+_50375037 0.69 ENST00000398452.6
ENST00000417656.6
ENST00000488454.5
ENST00000285116.8
ENST00000494518.1
spindle and kinetochore associated complex subunit 1
chr19_-_19628197 0.69 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr12_-_133235877 0.68 ENST00000419717.3
ENST00000545940.6
anomalous homeobox
chr21_-_32279012 0.68 ENST00000290130.4
MIS18 kinetochore protein A
chr15_-_40108861 0.67 ENST00000354670.9
ENST00000559701.5
ENST00000557870.1
ENST00000558774.5
Bcl2 modifying factor
chr16_-_66801578 0.66 ENST00000433154.6
ENST00000673664.1
ENST00000559050.1
ENST00000558713.6
telomere repeat binding bouquet formation protein 1
chr11_-_74731385 0.66 ENST00000622063.4
ENST00000376332.8
chordin like 2
chr5_+_119268689 0.66 ENST00000274456.6
TNF alpha induced protein 8
chr1_-_197146620 0.66 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chrX_+_14873399 0.65 ENST00000380492.8
ENST00000482354.5
motile sperm domain containing 2
chr3_+_10026409 0.65 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr15_+_89243945 0.64 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FA complementation group I
chr6_+_160991727 0.64 ENST00000366919.6
ENST00000392142.9
ENST00000366920.6
ENST00000348824.11
mitogen-activated protein kinase kinase kinase 4
chr4_-_119628007 0.64 ENST00000420633.1
ENST00000394439.5
phosphodiesterase 5A
chr16_+_788614 0.64 ENST00000262315.14
ENST00000455171.6
ENST00000317063.10
chromosome transmission fidelity factor 18
chr1_+_32651485 0.63 ENST00000490500.5
ENST00000445722.2
RB binding protein 4, chromatin remodeling factor
chr19_-_47113756 0.63 ENST00000253048.10
zinc finger CCCH-type containing 4
chr7_-_100100716 0.62 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr20_-_59933346 0.62 ENST00000446834.5
synaptonemal complex protein 2
chr1_-_35769928 0.61 ENST00000373220.7
ENST00000520551.1
claspin
chr4_-_1712310 0.61 ENST00000488267.5
ENST00000429429.6
ENST00000489418.6
ENST00000480936.1
stem-loop binding protein
chr1_+_112674649 0.61 ENST00000369644.5
Mov10 RISC complex RNA helicase
chr12_+_109999422 0.61 ENST00000261739.9
ankyrin repeat domain 13A
chrX_-_48356688 0.60 ENST00000298396.7
ENST00000376893.7
SSX family member 3
chr1_-_37554277 0.60 ENST00000296215.8
Smad nuclear interacting protein 1
chr20_-_64079906 0.60 ENST00000332298.9
regulator of G protein signaling 19
chr19_-_6424772 0.60 ENST00000619396.4
ENST00000398148.7
KH-type splicing regulatory protein
chr8_+_123072667 0.60 ENST00000519418.5
ENST00000287380.6
ENST00000327098.9
ENST00000522420.5
ENST00000521676.5
TBC1 domain family member 31
chr6_+_52362088 0.60 ENST00000635984.1
ENST00000635760.1
ENST00000442253.3
EF-hand domain containing 1
progestin and adipoQ receptor family member 8
chr16_-_74607088 0.59 ENST00000565260.1
ENST00000447066.6
ENST00000205061.9
ENST00000422840.7
ENST00000627032.2
golgi glycoprotein 1
chr12_+_459925 0.59 ENST00000266383.10
beta-1,4-N-acetyl-galactosaminyltransferase 3
chr19_-_10517921 0.59 ENST00000439028.3
sphingosine-1-phosphate receptor 5
chr1_+_15409858 0.59 ENST00000375980.9
EF-hand domain family member D2
chr1_+_178725227 0.59 ENST00000367635.8
Ral GEF with PH domain and SH3 binding motif 2
chr11_-_74731148 0.59 ENST00000263671.9
ENST00000528789.1
chordin like 2
chr14_+_49598910 0.58 ENST00000298288.11
leucine rich repeat protein 1
chr1_+_59814786 0.58 ENST00000455990.5
hook microtubule tethering protein 1
chr14_+_63852951 0.57 ENST00000357395.7
ENST00000358025.7
ENST00000344113.8
ENST00000341472.9
ENST00000555002.6
spectrin repeat containing nuclear envelope protein 2
chr22_+_37051731 0.57 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
potassium channel tetramerization domain containing 17
chr5_+_892844 0.56 ENST00000166345.8
thyroid hormone receptor interactor 13
chr2_+_218568558 0.56 ENST00000627282.2
ENST00000542068.5
CCR4-NOT transcription complex subunit 9
chr11_-_72434330 0.56 ENST00000542555.2
ENST00000535990.5
ENST00000294053.9
ENST00000538039.6
ENST00000340729.9
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chr7_-_77798359 0.55 ENST00000257663.4
transmembrane protein 60
chr8_-_17246390 0.55 ENST00000520178.3
CCR4-NOT transcription complex subunit 7
chr17_+_79778135 0.55 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr7_-_149461056 0.55 ENST00000247930.5
zinc finger protein 777
chr20_-_37095985 0.54 ENST00000344359.7
ENST00000373664.8
RB transcriptional corepressor like 1
chr16_-_788329 0.54 ENST00000563560.1
ENST00000569601.5
ENST00000565809.5
ENST00000007264.7
ENST00000565377.1
ENST00000567114.5
RNA pseudouridine synthase domain containing 1
chr6_+_27133032 0.53 ENST00000359193.3
H2A clustered histone 11
chr20_-_59933623 0.53 ENST00000357552.8
ENST00000425931.1
synaptonemal complex protein 2
chr8_-_144517785 0.53 ENST00000617875.6
ENST00000621189.4
RecQ like helicase 4
chr1_-_226309071 0.53 ENST00000359525.2
ENST00000681046.1
ENST00000460719.5
lin-9 DREAM MuvB core complex component
chr19_-_31349408 0.52 ENST00000240587.5
teashirt zinc finger homeobox 3
chr4_+_177309866 0.52 ENST00000264596.4
nei like DNA glycosylase 3
chr11_-_116772972 0.52 ENST00000375445.7
ENST00000260210.5
BUD13 homolog
chr18_-_51197671 0.51 ENST00000406189.4
mex-3 RNA binding family member C
chr17_-_65056659 0.51 ENST00000439174.7
G protein subunit alpha 13
chr2_+_46941199 0.50 ENST00000319190.11
ENST00000394850.6
tetratricopeptide repeat domain 7A
chr2_-_37324696 0.50 ENST00000443187.1
protein kinase D3
chr14_+_88562952 0.50 ENST00000302216.12
ENST00000554602.5
ENST00000556945.5
ENST00000556158.5
ENST00000557607.5
ENST00000555799.5
ENST00000251038.10
ENST00000555755.5
zinc finger CCCH-type containing 14
chr1_+_178725147 0.50 ENST00000367634.6
Ral GEF with PH domain and SH3 binding motif 2
chr2_+_10122315 0.50 ENST00000360566.6
ribonucleotide reductase regulatory subunit M2
chr6_-_30690968 0.50 ENST00000376420.9
ENST00000376421.7
nurim
chr22_-_38455199 0.50 ENST00000303592.3
potassium inwardly rectifying channel subfamily J member 4
chr11_-_73141913 0.49 ENST00000458644.6
FCH and double SH3 domains 2
chr16_+_10944547 0.48 ENST00000409790.6
ENST00000409552.4
C-type lectin domain containing 16A
chr7_+_77798750 0.48 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
putative homeodomain transcription factor 2
chr1_+_112674722 0.48 ENST00000357443.2
Mov10 RISC complex RNA helicase
chr4_+_153344633 0.48 ENST00000622785.4
meiotic nuclear divisions 1
chr15_+_40695129 0.48 ENST00000423169.6
ENST00000557850.5
ENST00000382643.7
ENST00000267868.8
ENST00000645673.2
RAD51 recombinase
chr6_-_136792466 0.48 ENST00000359015.5
mitogen-activated protein kinase kinase kinase 5
chr15_+_36579604 0.48 ENST00000566621.6
ENST00000570265.6
ENST00000564586.5
ENST00000569302.6
CDAN1 interacting nuclease 1
chr1_+_173868350 0.48 ENST00000427304.5
ENST00000367702.1
zinc finger and BTB domain containing 37
chr1_+_229626170 0.48 ENST00000258243.7
URB2 ribosome biogenesis homolog
chr20_+_2101807 0.48 ENST00000381482.8
serine/threonine kinase 35
chr22_+_37051787 0.47 ENST00000456470.1
potassium channel tetramerization domain containing 17
chr1_+_185045515 0.47 ENST00000367509.8
ENST00000367510.8
ring finger protein 2
chr16_+_2460086 0.47 ENST00000569496.5
ENST00000567489.5
ENST00000361837.9
ENST00000563531.5
ENST00000483320.5
tubulin epsilon and delta complex 2
chr4_-_112636858 0.47 ENST00000503172.5
ENST00000505019.6
ENST00000309071.9
zinc finger GRF-type containing 1
chr17_-_81222949 0.46 ENST00000450824.7
ENST00000269392.8
centrosomal protein 131
chr2_+_10123171 0.46 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr19_-_48170323 0.46 ENST00000263274.12
ENST00000427526.6
DNA ligase 1
chr16_-_58629816 0.45 ENST00000564557.1
ENST00000317147.10
ENST00000569240.5
ENST00000441024.6
CCR4-NOT transcription complex subunit 1
chr17_+_36545504 0.45 ENST00000616019.1
gametogenetin binding protein 2
chr12_+_109900518 0.45 ENST00000312777.9
ENST00000536408.2
trichoplein keratin filament binding
chr8_-_66962563 0.45 ENST00000563496.2
transcription factor 24
chr14_+_93207229 0.44 ENST00000554232.5
ENST00000556871.5
ENST00000013070.11
ENST00000555113.5
ubiquitin protein ligase E3 component n-recognin 7
chr7_+_77798832 0.44 ENST00000415251.6
ENST00000275575.11
putative homeodomain transcription factor 2
chr2_+_218710904 0.44 ENST00000437755.1
tubulin tyrosine ligase like 4
chr7_-_103344588 0.44 ENST00000426036.6
ENST00000249270.11
ENST00000379263.8
ENST00000454277.5
ENST00000412522.1
DnaJ heat shock protein family (Hsp40) member C2
chr5_+_14664653 0.44 ENST00000284274.5
OTU deubiquitinase with linear linkage specificity
chr4_-_119627631 0.43 ENST00000264805.9
phosphodiesterase 5A
chr1_+_32651164 0.43 ENST00000373493.10
ENST00000373485.5
ENST00000458695.6
RB binding protein 4, chromatin remodeling factor
chr11_-_65084024 0.43 ENST00000275517.8
ENST00000404147.3
cell division cycle associated 5
chr6_+_135181361 0.43 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chrX_-_140505058 0.43 ENST00000370536.5
SRY-box transcription factor 3
chr15_+_40695423 0.42 ENST00000526763.6
ENST00000532743.6
RAD51 recombinase
chr17_-_48101087 0.42 ENST00000393408.7
chromobox 1
chr17_+_36544896 0.42 ENST00000611219.1
ENST00000613102.5
gametogenetin binding protein 2
chr14_+_102592611 0.42 ENST00000262241.7
REST corepressor 1
chr8_-_131040890 0.42 ENST00000286355.10
adenylate cyclase 8
chr6_+_57317602 0.41 ENST00000274891.10
ENST00000671770.1
ENST00000672107.1
ENST00000615550.5
DNA primase subunit 2
chr8_-_94895195 0.41 ENST00000308108.9
ENST00000396133.7
cyclin E2
chr5_+_119268744 0.41 ENST00000388882.5
TNF alpha induced protein 8
chr9_-_93955347 0.41 ENST00000253968.11
BARX homeobox 1
chr20_-_62475983 0.41 ENST00000252997.3
GATA binding protein 5
chr4_-_1712250 0.41 ENST00000318386.8
stem-loop binding protein
chr19_-_47471886 0.41 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chr10_+_110871941 0.41 ENST00000444997.1
programmed cell death 4
chr7_-_100436425 0.40 ENST00000292330.3
protein phosphatase 1 regulatory subunit 35
chr2_+_47403116 0.40 ENST00000645506.1
ENST00000406134.5
ENST00000233146.7
mutS homolog 2
chr19_-_10569022 0.40 ENST00000335766.2
cyclin dependent kinase inhibitor 2D
chr9_-_111794926 0.40 ENST00000682961.1
ENST00000374283.5
shortage in chiasmata 1
chr10_+_59176600 0.40 ENST00000373880.9
phytanoyl-CoA 2-hydroxylase interacting protein like
chr9_+_128552558 0.39 ENST00000372731.8
ENST00000630804.2
ENST00000372739.7
ENST00000627441.2
ENST00000358161.9
ENST00000636257.1
spectrin alpha, non-erythrocytic 1
chr10_-_86521737 0.39 ENST00000298767.10
WAPL cohesin release factor
chr10_-_29735873 0.39 ENST00000674490.1
supervillin
chr2_+_218568865 0.39 ENST00000295701.9
CCR4-NOT transcription complex subunit 9
chr20_+_38472811 0.39 ENST00000397042.7
ENST00000262879.11
ENST00000397040.5
Ral GTPase activating protein non-catalytic subunit beta
chr17_-_48101287 0.39 ENST00000495350.5
ENST00000402583.5
chromobox 1
chr6_-_70957029 0.39 ENST00000230053.11
beta-1,3-glucuronyltransferase 2
chr12_+_109900258 0.39 ENST00000405876.9
trichoplein keratin filament binding
chr7_-_100573865 0.39 ENST00000622764.3
Sin3A associated protein 25
chr19_-_48170295 0.39 ENST00000596549.5
DNA ligase 1
chr19_-_42390268 0.39 ENST00000597255.1
ENST00000222032.10
cornifelin
chr6_+_391743 0.39 ENST00000380956.9
interferon regulatory factor 4
chrX_-_14873027 0.38 ENST00000452869.1
ENST00000398334.5
ENST00000650831.1
ENST00000324138.7
FA complementation group B
chr15_-_74695936 0.38 ENST00000647659.1
ENST00000566828.5
enhancer of mRNA decapping 3
chr5_+_150357629 0.38 ENST00000650162.1
ENST00000377797.7
ENST00000445265.6
ENST00000323668.11
ENST00000643257.2
ENST00000646961.1
ENST00000513538.2
ENST00000439160.6
ENST00000394269.7
ENST00000427724.7
ENST00000504761.6
ENST00000513346.5
ENST00000515516.1
treacle ribosome biogenesis factor 1
chr1_-_1273815 0.38 ENST00000509720.5
ENST00000400930.8
ENST00000422076.5
ENST00000435198.5
ENST00000349431.11
ENST00000347370.6
ENST00000502382.1
ENST00000400929.6
ubiquitin conjugating enzyme E2 J2
chr19_-_10568968 0.38 ENST00000393599.3
cyclin dependent kinase inhibitor 2D
chr1_+_227728587 0.38 ENST00000679575.1
ENST00000475930.1
ENST00000680854.1
ENST00000681006.1
ENST00000366760.5
synaptosome associated protein 47
chr6_+_109691249 0.38 ENST00000675726.1
ENST00000674933.1
ENST00000676442.1
ENST00000674744.1
ENST00000675606.1
ENST00000675523.1
ENST00000675714.1
ENST00000368941.2
ENST00000454215.6
ENST00000676435.1
ENST00000674644.1
ENST00000675284.1
ENST00000674641.1
ENST00000230124.8
ENST00000675772.1
ENST00000675973.1
ENST00000675681.1
ENST00000675096.1
ENST00000675831.1
ENST00000674884.1
ENST00000415980.2
FIG4 phosphoinositide 5-phosphatase
chr4_+_127880876 0.38 ENST00000270861.10
ENST00000515069.5
ENST00000513090.5
ENST00000507249.5
polo like kinase 4
chr3_+_23945271 0.38 ENST00000312521.9
nuclear receptor subfamily 1 group D member 2
chr1_+_63367619 0.38 ENST00000263440.6
ALG6 alpha-1,3-glucosyltransferase
chr8_-_123396412 0.37 ENST00000287394.10
ATPase family AAA domain containing 2
chr10_+_110871903 0.37 ENST00000280154.12
programmed cell death 4
chr1_-_235866916 0.37 ENST00000389794.7
lysosomal trafficking regulator
chr17_+_68205453 0.37 ENST00000674770.2
archaelysin family metallopeptidase 2
chr1_-_35769958 0.37 ENST00000251195.9
ENST00000318121.8
claspin
chr11_+_67266437 0.37 ENST00000308595.10
ENST00000526285.1
G protein-coupled receptor kinase 2
chr15_-_29269750 0.37 ENST00000332303.6
NSE3 homolog, SMC5-SMC6 complex component
chr6_+_63636481 0.37 ENST00000509330.5
PHD finger protein 3
chrX_-_120985760 0.37 ENST00000433030.4
cancer/testis antigen family 47 member A1
chr16_+_30065777 0.37 ENST00000395240.7
ENST00000566846.5
aldolase, fructose-bisphosphate A
chr2_-_128028114 0.37 ENST00000259234.10
Sin3A associated protein 130

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.5 1.4 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 1.3 GO:0009386 translational attenuation(GO:0009386)
0.3 0.3 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.3 0.9 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 0.9 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.3 1.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.3 1.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.3 1.9 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.3 3.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.3 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.5 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 0.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 0.6 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.8 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.2 1.6 GO:0030538 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.2 0.7 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.2 0.4 GO:0040031 snRNA modification(GO:0040031)
0.2 0.8 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 1.0 GO:0072757 cellular response to camptothecin(GO:0072757)
0.2 0.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 2.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 0.6 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 1.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.4 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1 1.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.7 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.6 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 0.4 GO:0045082 interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.6 GO:0060718 primary sex determination(GO:0007538) chorionic trophoblast cell differentiation(GO:0060718)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.6 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.1 1.0 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.8 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.6 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1 1.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 1.4 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.3 GO:0031453 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.8 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.5 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 1.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.8 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.3 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.5 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.8 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.2 GO:0030718 inner cell mass cell fate commitment(GO:0001827) germ-line stem cell population maintenance(GO:0030718)
0.1 0.1 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.1 0.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.7 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.2 GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation(GO:0070145)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.2 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.8 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.9 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.6 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.1 0.6 GO:0007144 female meiosis I(GO:0007144)
0.0 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 1.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.7 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.8 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.6 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 1.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 1.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.4 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 2.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.7 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.9 GO:0007140 male meiosis(GO:0007140)
0.0 1.1 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0010266 response to vitamin B1(GO:0010266)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 1.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.6 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.2 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 1.0 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.4 GO:0007129 synapsis(GO:0007129)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.2 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.5 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.6 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4 1.1 GO:0075341 host cell PML body(GO:0075341)
0.3 0.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 2.8 GO:0072687 meiotic spindle(GO:0072687)
0.2 1.4 GO:0033186 CAF-1 complex(GO:0033186)
0.2 1.1 GO:0032301 MutSalpha complex(GO:0032301)
0.2 1.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 2.6 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 4.0 GO:0000800 lateral element(GO:0000800)
0.1 0.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 1.6 GO:0001940 male pronucleus(GO:0001940)
0.1 1.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.7 GO:0042025 host cell nucleus(GO:0042025)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 1.2 GO:0070187 telosome(GO:0070187)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0008278 cohesin complex(GO:0008278)
0.1 3.7 GO:0000791 euchromatin(GO:0000791)
0.1 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0098536 deuterosome(GO:0098536)
0.0 0.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 3.7 GO:0000922 spindle pole(GO:0000922)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.0 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 2.0 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.0 GO:0005956 protein kinase CK2 complex(GO:0005956)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 1.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 2.0 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 0.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 1.8 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 1.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.2 0.6 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 1.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.8 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 1.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.6 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 2.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.4 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 1.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.4 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.4 GO:0003896 DNA primase activity(GO:0003896)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.3 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815) aspartate-tRNA(Asn) ligase activity(GO:0050560)
0.1 0.5 GO:0000405 bubble DNA binding(GO:0000405)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.6 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.8 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0052629 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 2.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID ATR PATHWAY ATR signaling pathway
0.1 2.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 4.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 3.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 1.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 4.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 4.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.1 0.4 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.1 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 1.4 REACTOME MEIOSIS Genes involved in Meiosis
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis