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Illumina Body Map 2 (GSE30611)

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Results for E4F1

Z-value: 0.62

Motif logo

Transcription factors associated with E4F1

Gene Symbol Gene ID Gene Info
ENSG00000167967.16 E4F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E4F1hg38_v1_chr16_+_2223693_2223716-0.261.5e-01Click!

Activity profile of E4F1 motif

Sorted Z-values of E4F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_63572472 1.45 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chr1_+_26169891 1.40 ENST00000374266.7
ENST00000270812.6
zinc finger protein 593
chr6_+_139135063 1.36 ENST00000367658.3
hdc homolog, cell cycle regulator
chr12_+_53985138 1.21 ENST00000303460.5
homeobox C10
chr19_+_45001430 1.20 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr19_-_45584769 1.08 ENST00000263275.5
outer mitochondrial membrane lipid metabolism regulator OPA3
chr14_-_49586325 1.08 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
ribosomal protein S29
chr12_+_53985065 1.06 ENST00000515593.1
homeobox C10
chr17_+_28744002 1.04 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TNF receptor associated factor 4
chr6_-_32844643 1.03 ENST00000374881.3
proteasome 20S subunit beta 8
chr2_+_218880844 1.02 ENST00000258411.8
Wnt family member 10A
chr14_-_22919124 0.91 ENST00000555209.5
ENST00000554256.5
ENST00000557403.5
ENST00000359890.8
ENST00000557549.5
ENST00000555676.5
ENST00000557571.5
ENST00000557464.5
ENST00000554618.5
ENST00000556862.5
ENST00000555722.5
ENST00000346528.9
ENST00000542016.6
ENST00000399922.6
ENST00000557227.5
RNA binding motif protein 23
chr12_+_121712740 0.89 ENST00000449592.7
transmembrane protein 120B
chr17_+_28744034 0.87 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr11_+_809961 0.84 ENST00000321153.9
ENST00000530797.5
ribosomal protein lateral stalk subunit P2
chr7_-_140924900 0.84 ENST00000646891.1
ENST00000644969.2
B-Raf proto-oncogene, serine/threonine kinase
chr12_+_122078740 0.82 ENST00000319080.12
MLX interacting protein
chr11_+_810227 0.82 ENST00000530398.1
ribosomal protein lateral stalk subunit P2
chr17_+_45132600 0.75 ENST00000619916.4
ENST00000431281.5
ENST00000591859.5
acyl-CoA binding domain containing 4
chr22_-_38506295 0.75 ENST00000403230.3
DEAD-box helicase 17
chr8_-_65842051 0.74 ENST00000401827.8
phosphodiesterase 7A
chr6_+_30061231 0.72 ENST00000376782.6
ENST00000359374.8
ENST00000376785.2
ENST00000332435.10
RNA polymerase I subunit H
chr19_+_1941118 0.70 ENST00000255641.13
casein kinase 1 gamma 2
chr16_-_68023201 0.66 ENST00000332395.7
DEAD-box helicase 28
chr6_+_32844789 0.65 ENST00000414474.5
proteasome 20S subunit beta 9
chr16_-_3717505 0.63 ENST00000538171.5
ENST00000246957.10
TNF receptor associated protein 1
chr14_+_100239121 0.62 ENST00000262238.10
YY1 transcription factor
chr3_+_38165484 0.62 ENST00000446845.5
ENST00000311806.8
oxidative stress responsive kinase 1
chr4_-_110636963 0.61 ENST00000394595.8
paired like homeodomain 2
chr6_-_34696733 0.60 ENST00000374023.8
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr22_-_38506320 0.58 ENST00000396821.8
DEAD-box helicase 17
chr10_+_133308874 0.58 ENST00000361518.10
ENST00000359035.4
zinc finger protein 511
chr6_-_34696839 0.58 ENST00000374026.7
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr7_-_129952901 0.56 ENST00000472396.5
ENST00000355621.8
ubiquitin conjugating enzyme E2 H
chr6_-_27473058 0.56 ENST00000683788.1
ENST00000211936.10
zinc finger protein 184
chr17_-_42388360 0.53 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr6_-_27472681 0.53 ENST00000377419.1
zinc finger protein 184
chr7_-_140924699 0.53 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
B-Raf proto-oncogene, serine/threonine kinase
chr16_+_31459950 0.51 ENST00000564900.1
armadillo repeat containing 5
chr2_-_156332694 0.51 ENST00000424077.1
ENST00000426264.5
ENST00000421709.1
ENST00000339562.9
nuclear receptor subfamily 4 group A member 2
chr17_-_42388467 0.51 ENST00000678792.1
ENST00000679166.1
ENST00000677442.1
ENST00000677723.1
ENST00000678905.1
ENST00000677479.1
ENST00000678043.1
ENST00000677152.1
ENST00000677603.1
ENST00000588969.5
ENST00000678535.1
ENST00000679185.1
ENST00000677030.1
ENST00000679014.1
ENST00000678044.1
ENST00000678827.1
signal transducer and activator of transcription 3
chr22_+_40857076 0.51 ENST00000614001.1
ENST00000357137.9
X-prolyl aminopeptidase 3
chr1_-_228103235 0.50 ENST00000272139.5
chromosome 1 open reading frame 35
chr2_+_10044175 0.50 ENST00000440320.5
ENST00000535335.1
Kruppel like factor 11
chr20_+_45791978 0.50 ENST00000449078.5
ENST00000456939.5
deoxynucleotidyltransferase terminal interacting protein 1
chr20_+_45791930 0.50 ENST00000372622.8
deoxynucleotidyltransferase terminal interacting protein 1
chr11_-_6612141 0.49 ENST00000527248.2
ENST00000299424.9
TATA-box binding protein associated factor 10
chr2_-_60553409 0.49 ENST00000358510.6
ENST00000643004.1
BAF chromatin remodeling complex subunit BCL11A
chr2_+_10043524 0.48 ENST00000305883.6
Kruppel like factor 11
chr12_+_56118396 0.47 ENST00000546903.1
zinc finger CCCH-type containing 10
chr17_+_7572818 0.46 ENST00000293831.13
ENST00000582169.5
ENST00000578754.5
ENST00000578495.5
ENST00000585024.5
ENST00000583802.5
ENST00000577269.5
ENST00000584784.5
ENST00000582746.5
ENST00000581621.1
eukaryotic translation initiation factor 4A1
novel transcript
chr10_+_117241107 0.46 ENST00000644641.2
solute carrier family 18 member A2
chr6_-_162727686 0.44 ENST00000647006.2
parkin RBR E3 ubiquitin protein ligase
chr19_-_10231293 0.44 ENST00000646641.1
sphingosine-1-phosphate receptor 2
chr11_+_12674555 0.44 ENST00000527376.3
TEA domain transcription factor 1
chr20_-_5610980 0.44 ENST00000379019.7
glycerophosphocholine phosphodiesterase 1
chr9_+_122264857 0.41 ENST00000344641.8
ENST00000441707.5
ENST00000373723.9
ENST00000373729.5
mitochondrial ribosome recycling factor
chr5_-_95961830 0.41 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr2_+_74958635 0.39 ENST00000483063.2
DNA polymerase epsilon 4, accessory subunit
chr6_+_47477731 0.39 ENST00000359314.5
CD2 associated protein
chr22_+_38705922 0.39 ENST00000216044.10
GTP binding protein 1
chr12_-_109573482 0.38 ENST00000540016.5
ENST00000545712.7
metabolism of cobalamin associated B
chr6_+_109978297 0.38 ENST00000275169.5
G protein-coupled receptor 6
chr22_-_40856565 0.38 ENST00000620312.4
ENST00000216218.8
ST13 Hsp70 interacting protein
chr7_-_87220520 0.38 ENST00000455575.1
transmembrane protein 243
chr1_-_70354673 0.37 ENST00000370944.9
ENST00000262346.6
ankyrin repeat domain 13C
chr6_+_33208488 0.37 ENST00000374656.5
ring finger protein 1
chr20_-_45972171 0.36 ENST00000322927.3
zinc finger protein 335
chr1_+_180230257 0.36 ENST00000263726.4
LIM homeobox 4
chr11_+_18698768 0.36 ENST00000280734.3
transmembrane protein 86A
chrX_-_153971810 0.36 ENST00000310441.12
host cell factor C1
chr1_-_31644866 0.35 ENST00000373703.5
penta-EF-hand domain containing 1
chr6_-_144095556 0.35 ENST00000367569.4
splicing factor 3b subunit 5
chr19_+_54201122 0.34 ENST00000391753.6
ENST00000441429.1
ribosomal protein S9
chr6_+_109978256 0.34 ENST00000414000.3
G protein-coupled receptor 6
chr8_-_29350666 0.34 ENST00000240100.7
dual specificity phosphatase 4
chr12_-_109573547 0.33 ENST00000537236.2
metabolism of cobalamin associated B
chr1_-_16156059 0.33 ENST00000358432.8
EPH receptor A2
chr9_-_128881922 0.32 ENST00000320665.10
ENST00000436267.7
ENST00000302586.8
ENST00000651925.1
kynurenine aminotransferase 1
kynurenine aminotransferase 1
chr11_-_31817904 0.32 ENST00000423822.7
paired box 6
chr10_+_97737115 0.32 ENST00000337540.11
ENST00000370613.7
ENST00000370610.7
ENST00000357540.8
ENST00000393677.8
ENST00000423811.3
ENST00000684270.1
ENST00000359980.5
zinc finger FYVE-type containing 27
chr2_-_60553474 0.31 ENST00000409351.5
BAF chromatin remodeling complex subunit BCL11A
chr16_+_68023249 0.30 ENST00000358896.10
ENST00000568099.6
dihydrouridine synthase 2
chr11_+_66421004 0.30 ENST00000639555.1
ENST00000311034.7
neuronal PAS domain protein 4
chr10_+_63133247 0.30 ENST00000435510.6
nuclear receptor binding factor 2
chr9_+_122264603 0.30 ENST00000297908.7
mitochondrial ribosome recycling factor
chr19_+_54200849 0.30 ENST00000626547.2
ENST00000302907.9
ENST00000391752.5
ENST00000402367.5
ENST00000391751.7
ribosomal protein S9
chr3_-_185938006 0.29 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
transformer 2 beta homolog
chr11_-_3797490 0.29 ENST00000397004.8
ENST00000397007.8
ENST00000532475.1
ENST00000324932.12
nucleoporin 98 and 96 precursor
chr16_+_81444799 0.28 ENST00000537098.8
c-Maf inducing protein
chr17_+_57256514 0.28 ENST00000284073.7
ENST00000674964.1
musashi RNA binding protein 2
chr11_-_3797458 0.27 ENST00000355260.7
nucleoporin 98 and 96 precursor
chr10_+_63133279 0.27 ENST00000277746.11
nuclear receptor binding factor 2
chr1_-_8026283 0.26 ENST00000474874.5
ENST00000469499.5
ENST00000377482.10
ERBB receptor feedback inhibitor 1
chr15_-_40755223 0.26 ENST00000560460.5
ENST00000338376.8
ENST00000560905.1
regulator of microtubule dynamics 3
chrX_-_84502442 0.26 ENST00000297977.9
ENST00000506585.6
ENST00000373177.3
ENST00000449553.2
highly divergent homeobox
chr1_+_63322558 0.26 ENST00000371116.4
forkhead box D3
chr16_+_68023276 0.26 ENST00000567100.5
ENST00000565263.6
ENST00000432752.5
ENST00000569289.5
ENST00000564781.1
dihydrouridine synthase 2
chr10_-_133308844 0.25 ENST00000682905.1
ENST00000682515.1
ENST00000683612.1
ENST00000252936.8
ENST00000417178.7
ENST00000682161.1
ENST00000683014.1
ENST00000683060.1
ENST00000683383.1
tubulin gamma complex associated protein 2
chr19_-_10231271 0.25 ENST00000592342.5
ENST00000588952.5
DNA methyltransferase 1
chr18_+_26226417 0.24 ENST00000269142.10
TATA-box binding protein associated factor 4b
chr5_+_138875230 0.24 ENST00000522013.5
ENST00000520260.5
ENST00000523298.5
ENST00000520865.5
ENST00000519634.5
ENST00000517533.5
ENST00000523685.5
ENST00000519768.5
ENST00000517656.5
ENST00000521683.5
ENST00000521640.5
ENST00000519116.5
catenin alpha 1
chr17_+_41688879 0.23 ENST00000469257.2
ENST00000591776.5
eukaryotic translation initiation factor 1
chr3_-_101677092 0.22 ENST00000461821.1
zinc finger and BTB domain containing 11
chr6_-_31806937 0.22 ENST00000375661.6
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr22_+_17638796 0.21 ENST00000355028.4
BCL2 like 13
chr19_-_58554960 0.21 ENST00000596708.1
ENST00000601220.5
ENST00000597848.1
charged multivesicular body protein 2A
chr1_-_212035513 0.21 ENST00000366992.7
ENST00000366993.7
ENST00000440600.6
ENST00000366994.8
integrator complex subunit 7
chr11_-_3797746 0.21 ENST00000359171.8
nucleoporin 98 and 96 precursor
chr5_+_134371561 0.21 ENST00000265339.7
ENST00000506787.5
ENST00000507277.1
ubiquitin conjugating enzyme E2 B
chr19_+_13747887 0.19 ENST00000221554.13
ENST00000586666.5
coiled-coil domain containing 130
chr4_+_74445302 0.18 ENST00000502307.1
amphiregulin
chr18_+_26226472 0.18 ENST00000578121.5
TATA-box binding protein associated factor 4b
chr19_-_45584810 0.17 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr20_+_35615812 0.17 ENST00000679710.1
ENST00000374273.8
sperm associated antigen 4
chr3_-_101677119 0.17 ENST00000312938.5
zinc finger and BTB domain containing 11
chr2_-_240025380 0.16 ENST00000676782.1
ENST00000677407.1
ENST00000678914.1
ENST00000677294.1
ENST00000676491.1
ENST00000677567.1
ENST00000679158.1
ENST00000448880.6
ENST00000677263.1
ENST00000678289.1
ENST00000678737.1
NADH:ubiquinone oxidoreductase subunit A10
chr2_-_60553618 0.16 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BAF chromatin remodeling complex subunit BCL11A
chr17_+_782340 0.15 ENST00000304478.9
mitochondrial rRNA methyltransferase 3
chr12_-_51173067 0.15 ENST00000549867.5
ENST00000257915.10
transcription factor CP2
chr16_+_29962049 0.15 ENST00000279396.11
ENST00000575829.6
ENST00000561899.6
transmembrane protein 219
chr17_-_782253 0.15 ENST00000628529.2
ENST00000625892.1
ENST00000301328.9
ENST00000576419.1
glyoxalase domain containing 4
chr1_-_46719074 0.15 ENST00000371933.8
ENST00000672422.2
ENST00000674263.1
ENST00000674415.1
ENST00000674435.1
EF-hand calcium binding domain 14
chr10_-_133308817 0.15 ENST00000543663.6
tubulin gamma complex associated protein 2
chr5_+_113513674 0.14 ENST00000161863.9
ENST00000515883.5
YTH domain containing 2
chr21_-_39349048 0.14 ENST00000380748.5
ENST00000380749.10
high mobility group nucleosome binding domain 1
chr17_-_782317 0.14 ENST00000301329.10
glyoxalase domain containing 4
chr6_+_15248855 0.14 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr6_+_44387686 0.13 ENST00000371477.4
cell division cycle 5 like
chr19_-_58555085 0.13 ENST00000312547.7
charged multivesicular body protein 2A
chr22_+_17638584 0.12 ENST00000337612.9
ENST00000418951.6
ENST00000538149.5
ENST00000543133.5
ENST00000611738.4
ENST00000616863.4
ENST00000618481.4
ENST00000317582.10
ENST00000493680.5
BCL2 like 13
chr11_-_1572261 0.12 ENST00000397374.8
dual specificity phosphatase 8
chr2_-_219543793 0.12 ENST00000243776.11
chondroitin polymerizing factor
chr19_-_29213110 0.11 ENST00000304863.6
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr4_+_74445126 0.10 ENST00000395748.8
amphiregulin
chr2_-_60553558 0.10 ENST00000642439.1
ENST00000356842.9
BAF chromatin remodeling complex subunit BCL11A
chr4_-_67701113 0.10 ENST00000420827.2
ENST00000322244.10
ubiquitin like modifier activating enzyme 6
chr17_-_4739866 0.10 ENST00000574412.6
ENST00000293778.12
C-X-C motif chemokine ligand 16
chr19_-_42255119 0.09 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr7_-_87220567 0.09 ENST00000433078.5
transmembrane protein 243
chr17_+_18183803 0.09 ENST00000399138.5
alkB homolog 5, RNA demethylase
chr5_+_57174016 0.09 ENST00000514387.6
ENST00000506184.7
GC-rich promoter binding protein 1
chr18_+_48539198 0.09 ENST00000591412.5
cap binding complex dependent translation initiation factor
chr14_+_60249191 0.08 ENST00000395076.9
protein phosphatase, Mg2+/Mn2+ dependent 1A
chr10_-_62816309 0.08 ENST00000411732.3
early growth response 2
chr14_+_60249387 0.08 ENST00000325658.3
protein phosphatase, Mg2+/Mn2+ dependent 1A
chr6_-_53348902 0.08 ENST00000370913.5
ENST00000304434.11
ELOVL fatty acid elongase 5
chr2_-_240025299 0.07 ENST00000404554.5
ENST00000407129.3
ENST00000307300.8
ENST00000678455.1
ENST00000444548.6
ENST00000252711.7
ENST00000620965.5
ENST00000443626.5
NADH:ubiquinone oxidoreductase subunit A10
chr19_+_42076129 0.07 ENST00000359044.5
zinc finger protein 574
chr5_+_57173948 0.07 ENST00000424459.7
GC-rich promoter binding protein 1
chr2_-_61888570 0.07 ENST00000394440.8
ENST00000544079.2
chaperonin containing TCP1 subunit 4
chr19_+_33796268 0.07 ENST00000587559.5
ENST00000588637.5
potassium channel tetramerization domain containing 15
chr1_+_13700176 0.06 ENST00000484063.6
PR/SET domain 2
chr22_+_38705737 0.06 ENST00000484657.5
GTP binding protein 1
chr12_-_51172779 0.06 ENST00000548108.1
ENST00000548115.5
transcription factor CP2
chr17_+_27294076 0.06 ENST00000581440.5
ENST00000583742.1
ENST00000579733.5
ENST00000583193.5
ENST00000581185.5
ENST00000427287.6
ENST00000262394.7
ENST00000348811.6
WD repeat and SOCS box containing 1
chr2_-_75199511 0.05 ENST00000305249.10
tachykinin receptor 1
chr1_-_1349368 0.05 ENST00000378888.10
dishevelled segment polarity protein 1
chr16_-_27549887 0.04 ENST00000561623.5
ENST00000356183.9
general transcription factor IIIC subunit 1
chr17_+_57256727 0.03 ENST00000675656.1
musashi RNA binding protein 2
chr5_-_138875362 0.03 ENST00000518785.1
leucine rich repeat transmembrane neuronal 2
chr9_-_122264798 0.03 ENST00000417201.4
RNA binding motif protein 18
chr2_-_215436061 0.02 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr20_+_59604527 0.02 ENST00000371015.6
phosphatase and actin regulator 3
chr3_+_150408314 0.02 ENST00000361875.7
TSC22 domain family member 2
chr19_-_9913819 0.01 ENST00000593091.2
olfactomedin 2
chr19_+_3506355 0.01 ENST00000652521.1
fizzy and cell division cycle 20 related 1
chr4_+_1871373 0.00 ENST00000508803.6
ENST00000507820.5
ENST00000514045.5
nuclear receptor binding SET domain protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of E4F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.3 1.0 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.6 GO:0009386 translational attenuation(GO:0009386)
0.2 0.6 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.2 1.1 GO:2000173 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 1.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 1.4 GO:2000301 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.7 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 0.6 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 0.5 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.7 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.8 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.5 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 2.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.3 GO:1901491 axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 1.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.4 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.3 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.1 1.0 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.7 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.4 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:0060903 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.0 0.4 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.3 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 1.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.3 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.3 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 1.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0090309 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.5 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 2.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 1.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) convergent extension involved in organogenesis(GO:0060029)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 1.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.5 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.3 GO:0070546 cysteine-S-conjugate beta-lyase activity(GO:0047804) L-phenylalanine aminotransferase activity(GO:0070546)
0.1 0.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.0 1.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.1 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening